EP2782543B1 - Flacon de collecte de plasma sanguin - Google Patents
Flacon de collecte de plasma sanguin Download PDFInfo
- Publication number
- EP2782543B1 EP2782543B1 EP12790854.9A EP12790854A EP2782543B1 EP 2782543 B1 EP2782543 B1 EP 2782543B1 EP 12790854 A EP12790854 A EP 12790854A EP 2782543 B1 EP2782543 B1 EP 2782543B1
- Authority
- EP
- European Patent Office
- Prior art keywords
- lid
- flask
- blood plasma
- neck
- plasma collecting
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Not-in-force
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/1443—Containers with means for dispensing liquid medicaments in a filtered or sterile way, e.g. with bacterial filters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
- A61J1/10—Bag-type containers
- A61J1/12—Bag-type containers with means for holding samples of contents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/1412—Containers with closing means, e.g. caps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/1475—Inlet or outlet ports
- A61J1/1487—Inlet or outlet ports with friction fit, e.g. connecting tubes directly to a protruding port
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/1443—Containers with means for dispensing liquid medicaments in a filtered or sterile way, e.g. with bacterial filters
- A61J1/145—Containers with means for dispensing liquid medicaments in a filtered or sterile way, e.g. with bacterial filters using air filters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/1443—Containers with means for dispensing liquid medicaments in a filtered or sterile way, e.g. with bacterial filters
- A61J1/1456—Containers with means for dispensing liquid medicaments in a filtered or sterile way, e.g. with bacterial filters using liquid filters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/2068—Venting means
Definitions
- the present invention relates to a blood plasma collection bottle made of plastic for storing blood plasma in the frozen state with a bottle body having a bottleneck on its upper side.
- Blood plasma collection containers have been known in the form of plastic bags for many years and have proven themselves through the use of materials such as ethylene-vinyl acetate (EVA) and polyethylene (PE) during freezing.
- EVA ethylene-vinyl acetate
- PE polyethylene
- the disadvantage of blood plasma collection containers in the form of blood bags is the poor handling, as they can not be set up without tools or special designs and also there is a risk that they will be damaged in the frozen state when dropped. In addition, they bulge out unchecked, so that the amount is difficult to control.
- the bottle body in horizontal section has a cross-section rectangular basic shape and has on its upper side a closed by a cover bottle neck.
- two connection points are provided, one of which is provided a connection point for filling the bottle body with blood plasma and the other connection point of the venting and sampling is used.
- a lid can be fastened to protect the connection points. This has two slots, which serve the implementation of fixed at the connection points hoses.
- the lid is in a position where the tubing passes unhindered through the slots. After completion of the plasma donation, the tubes are cut off and welded. To fix the free ends of the cut tubes, the lid is rotated, pulling the free ends into the lid.
- EP 2 433 608 also describes a plastic blood plasma collection bottle for storing blood plasma in the frozen state.
- Object of the present invention is therefore to design a blood plasma collection bottle made of plastic for the storage of plasma in the frozen state of the type mentioned so that their handling is improved.
- the operability is simplified and the dimensional stability can be increased.
- connection points are provided on the upper side of the bottle body on opposite sides of the bottle neck and laterally spaced from this connection points with connecting pieces, wherein the one connection point filling the bottle body with blood plasma and the sampling is used and to the connecting piece this connection point is provided with an L-shaped connector, whose one connector leg is connected to the connection piece and whose other connector leg is directed towards the bottle neck and carries a hose, and wherein the other connection point serves for aeration or venting of the bottle body and at the connecting piece of this connection point a preferably hydrophilic sterile filter is provided.
- connection point is designed such that it serves to fill the bottle body with blood plasma and to take the sample.
- an L-shaped connector is provided, whose one connector leg is directed towards the bottleneck.
- the other connection piece is used only for venting when filling with blood plasma or the ventilation during sampling, so that both processes can be carried out easily.
- This connection piece is equipped with a preferably hydrophilic sterile filter. This can be inserted in the connection piece.
- the L-shaped connectors are permanently attached to the connecting piece.
- the connectors may be glued or welded to the spigot.
- they are non-detachable and self-sealingly fixed to the connecting piece by means of a latching connection.
- corresponding sealing surfaces can be formed on the connecting piece and the L-shaped connectors, which come into contact with each other in particular under pressure when the L-shaped connectors are fixed to the connecting piece.
- the sealing surfaces may be provided, for example, at the upper edge of the connecting piece and a corresponding annular surface on the inside of the connector.
- a sample tube or pilot tube is usually used for sampling.
- the hose carries at least one pilot bag at its end, the pilot bag having a vent in which a hydrophilic frit is provided.
- the sampling takes place in a simple manner in that the blood plasma collection container is tilted so that liquid flows from the container into the pilot bag. Subsequently, the pilot bag is sealed by its container-side end is welded. Furthermore, the vent is closed. This is preferably formed in a tubular Absch spaende the pilot bag, in which also the hydrophilic frit is positioned, so that the vent opening can be closed by welding the Absch spaendes.
- pilot bags are connected to the hose of the connection point for the venting and sampling via a corresponding, in particular Y-shaped connecting hose.
- a connection site serves both to fill the bottle body with blood plasma and to take the sample
- the tube connected to the corresponding connector must branch, with one free end to be connected to the blood plasma apparatus and to the other free one End the pilot tubes or pilot bags are attached.
- a lid can be fixed or fixable to the bottleneck and in particular to a cover flap closing the top of the bottle. This is designed such that it engages over the bottle neck protruding portions of the tubes in the fixed state and so positioned.
- the cover can be designed so that it overlaps in the fixed state, the connection points and also protects from access from the outside.
- the cover has the connectors / hoses associated and open towards the lid bottom recesses, which engage with the projecting over the bottle neck tube sections and are penetrated by these, when the lid is fixed to the neck of the bottle.
- the lid may have on the inside holding webs, which engage over the long connector legs / hose sections and position when the lid is fixed to the bottle neck.
- a latching mechanism is provided, via which the lid is fixed to the bottle neck and in particular the cover plate when the lid is pressed onto the bottleneck from above.
- the latching mechanism according to a further aspect of the invention, a first detent position, in which the lid can be released again from the bottle neck, and a second detent position, in which the lid is further pressed onto the bottle neck than in the first detent position and in the a release of the lid is prevented from the bottleneck on.
- the cover is releasably attached to the bottleneck as delivered, i. he is locked in the upper, first resting point. This makes it possible to detach the lid for filling the blood plasma collection bottle and then welding off the connectors from the bottleneck. After welding off the lid can then be finally fixed to the bottle neck by being brought into the second detent position in which a release is no longer possible.
- latching noses are formed on the lower, open edge of the lid, which engage when pressing the lid on the bottleneck with a retaining web formed on the bottleneck and in particular the outer edge region of the cover, are elastically expanded and at resiliently spring back further impressions and engage behind the retaining web to produce the first detent position.
- a latching opening may be formed in the web, in which engages a receiving side provided latching element in the second detent position.
- retaining elements in particular holding clips for the detachable attachment of sample tubes, are provided on the lid and in particular on the top side of the lid. This embodiment offers the possibility to deliver the sample tubes as a unit with the blood plasma collection bottle.
- the side surfaces of the bottle body can each define a flat or slightly inwardly curved region, followed by rounded areas to the end surfaces. It has been shown that bottle bodies shaped in this way are particularly dimensionally stable. This is especially true when the areas are slightly curved inward, with the dome having a maximum depth of 2mm, especially 1.5mm from the edges of the dome. The inward curvature a kind of bias is achieved, which counteracts buckling of the bottle body during filling.
- the stability of the bottle is further increased when the flat or slightly inwardly curved portions have a hexagonal shape whose bases are at the transitional areas of the side surfaces lie to the top and bottom of the bottle body and are preferably configured such hexagonal evenly that the lying between the bases corners are positioned approximately at the central height of the bottle body.
- the bottle body then has a shape obtained by flattening an oval or round body, in which case the sides of the hexagonal faces lying between the bases are slightly rounded.
- the bottle body may include a plurality of stiffening beads that extend around the bottle body and are preferably positioned to function, at least in part, as a level indicator.
- a total of four stiffening beads may be formed on the bottle body, wherein in particular two stiffening beads are provided on the upper bottle body half and two stiffening beads in the lower bottle body half.
- the blood plasma collection bottle is made of plastic, in particular polyethylene (PE) and has a bottle body 1, which has a cross-section rectangular basic shape in horizontal section and carries on its upper side a bottle neck 2 with a top provided cover plate 2a.
- PE polyethylene
- the side surfaces of the bottle body 1 each define a flat portion 3 of hexagonal shape
- the bases 3a, 3b lie at the transition areas of the side surfaces to the top and bottom of the bottle body 1, wherein between the bases 3a, 3b lying corners E are positioned approximately at the central height of the bottle body 1.
- the sides 3c, 3d, 3e, 3f of the hexagonal surface 3 lying between the base sides 3a, 3b are slightly rounded off.
- the bottle body 1 close to the end faces, which have a rounded shape.
- the bottle body 1 has a shape that is obtained when flattening a base round or oval shape.
- the flat areas 3 can also be slightly curved inwards, the curvature in the center of the hexagonal area 3 having a depth of about 1.5 mm with respect to the edges of the hexagonal area 3.
- the bottle body 1 has a total of four stiffening beads 5, which extend around the bottle body 1, wherein two stiffening beads 5 are provided in the upper bottle body half and two stiffening beads 5 in the lower bottle body half.
- the upper two stiffening beads 5 act as a level indicator.
- three adjustable feet 4 are provided, by which it is ensured that the flat blood plasma collection bottle can be stably placed.
- connection points 7a, 7b are provided on opposite sides of the bottle neck 2 and laterally spaced therefrom, one of which 7a serves to fill the bottle body 1 with blood plasma and the other connection point 7b serves for venting and sampling.
- connection points 7a, 7b firmly connected to the bottle body 1 connecting piece 8 are provided, on which L-shaped connectors 9 are held insoluble.
- the bottle body 1 may have two connection points 7c, 7d, of which one connection point 7a serves both for filling the bottle body 1 with blood plasma and for sampling.
- one connection point 7a serves both for filling the bottle body 1 with blood plasma and for sampling.
- an attachment piece 8 of the connection point 7c serving for filling and sampling is provided with an L-shaped connector 9.
- the connecting piece 8 of the other connection point 7d is used only for loading and bleeding the bottle body 1.
- a non-illustrated hydrophilic sterile filter is housed.
- the L-shaped connectors 9 are fixed to the connecting piece 8 by a latching mechanism.
- a latching mechanism for this purpose, in the lower end region of the connecting piece 8 an outwardly projecting latching shoulder 8a and the inside of the connectors 9 a corresponding latching lug 9a is formed, which engages the latching shoulder 8a latching when a connector 9 pressed onto a connecting piece 8 becomes.
- FIG. 11 shown that on the inside of the connectors 9 each have a sealing surface 9a is formed, which comes to a sealing surface 8b at the upper edge of the corresponding connecting piece 8 sealingly and under pressure into contact when the connector 9 is fixed to the connecting piece 8.
- hoses 10 are attached at the points away from the connecting piece 8 at the points away from the connecting piece 8 at the points away from the connecting piece 8 connector legs hoses 10 are attached.
- the arrangement is made such that the connector legs pointing away from the connecting piece 8 are directed to the bottle neck 2, so that the tubes 10 held thereon extend over the cover plate 2a of the bottle neck 2.
- the hoses 10 are shown in the welded state, in which the hose ends are located directly above the cover plate 2a. In unabgesch spatem state, the tubes 10 are significantly longer.
- a lid 11 is fixed on the cover plate 2a of the bottle neck 2, a lid 11 is fixed. This is designed such that it overlaps in the fixed state over the bottle neck 2 projecting portions of the tubes 10 and protects against access from the outside. Specifically, the lid 11 the hoses 10 associated and the lid bottom side open, slot-shaped recesses 12, which come into engagement with the projecting over the bottle neck 2 tube sections and are penetrated by these when the lid 11 is fixed to the bottle neck 2. Like in the FIG. 12 is shown, the lid 11 may also be formed so wide that it surrounds the L-shaped connectors 9.
- the latching mechanism comprises a first detent position, in which the lid 11 are released again from the bottle neck 2 can, and a second detent position in which a release of the lid 11 of the bottle neck 2 is substantially no longer possible.
- latching lugs 13 are formed on the lower, open lid edge, which come when depressing the lid 11 on the bottle neck 2 with the outer edge region of the cover plate 2 engage, are elastically expanded and elastically spring back on further depression of the lid 11 and to produce the first Detent position engage behind the cover plate 2a.
- an upright projecting web 14 is formed on the upper side of the cover plate 2a and a receptacle 15 corresponding to the web 14 is formed on the inner side of the cover, which engage with one another when the cover 11 is pressed onto the bottle neck 2.
- 14 resting latching opening 16 is formed on the web, with which a receiving side provided latching tooth 12 engages when the lid 11 is pushed beyond the first detent position on the bottle neck 2 in the second detent position.
- the engagement region between the latching opening 16 and the latching tooth 17 is not accessible from the outside, so that a release of this connection is prevented.
- the lid 11 carries at its top retaining clips 18 for releasably attaching sample tube 19.
- the lid 11 is fixed on the bottleneck 2 via the upper, first latching point.
- the lid 11 is removed, and then the tubes 10 are welded so that they fit under the lid 11.
- the lid 11 is again attached to the bottle neck 2 and thereby depressed so far that a fixation on the second detent position takes place, so that a renewed removal of the lid 11 is prevented.
- the hoses 10 are inaccessible for subsequent manipulation.
- FIG. 13 an embodiment is shown in which instead of sampling tube two pilot bags 20 are connected to the sampler serving connector 9.
- the hose 10 which is connected to the free end of the L-shaped connector 9 at the sampling point serving connection 7 b, connected at its free end via a Y-shaped connecting hose 21 with the two pilot bags 20.
- the pilot bags 20 have a hose-like Absch doende 22 with a vent opening 23, wherein in the Absch bulkende 22, a hydrophilic frit 24 is housed.
- the sampling is carried out in a simple manner in that the blood plasma collection container is tilted so that liquid flows from the bottle body 1 into the two pilot bags 20 until the hydrophilic frit 24 closes. Subsequently, the pilot bags 20 are welded at their two Absch doenden 22.
- Y-shaped connecting tube 21 may also be provided a connecting tube with three or more ports, the other ports then form ventilation openings in which hydrophilic sterile filter or frits are provided, via which air can escape from the bottle body 1 during the filling of the blood plasma collection container ,
- the hose 10 has a further branch, via which then the filling of the bottle takes place.
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- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Hematology (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Sampling And Sample Adjustment (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
Claims (13)
- Bouteille de collecte de plasma sanguin en plastique pour la conservation de plasma sanguin à l'état congelé avec un corps de bouteille (1) qui présente un goulot (2) sur sa face supérieure, la face supérieure du corps de bouteille (1) comportant, sur deux côtés du goulot opposés l'un à l'autre et latéralement éloignés de ce dernier, des points de raccordement (7c, 7d) avec des tubulures de raccordement (8), ledit point de raccordement (7c) servant au remplissage du corps de bouteille (1) avec du plasma sanguin ainsi qu'à la prise d'échantillons, et la tubulure de raccordement (8) de ce point de raccordement (7c) comportant un connecteur en L (9) dont l'une des broches est reliée à la tubulure de raccordement (8) et l'autre est dirigée vers le goulot (2) et comporte un tube (10), l'autre point de raccordement (7d) servant à l'aération/la purge du corps de bouteille (1), caractérisée en ce que en ce que la tubulure de raccordement (8) de ce point de raccordement (7d) présente un filtre stérile idéalement hydrophile.
- Bouteille de collecte de plasma sanguin selon la revendication 1, caractérisée en ce qu'au moins un connecteur en L (9) est maintenu sur la tubulure de raccordement (8) de façon amovible et autoétanche à l'aide d'une connexion par encliquetage, les tubulures de raccordement (8) et le connecteur en L (9) présentant notamment des surfaces d'étanchéité correspondantes (8b, 9b) venant notamment s'appuyer de façon réciproque sous l'effet de la pression lorsque le connecteur en L (9) est fixé à la tubulure de raccordement (8).
- Bouteille de collecte de plasma sanguin selon les revendications 1 ou 2. caractérisée en ce que le tube (10) relié au connecteur en L (9) au point de raccordement servant à la prise d' échantillons (7b, 7c) comporte sur son extrémité libre un sac pilote (20) avec lequel il est relié, le sac pilote (20) présentant une ouverture de purge (23) dans laquelle est configurée une fritte hydrophile (24).
- Bouteille de collecte de plasma sanguin selon la revendication 3, caractérisée en ce que le sac pilote (20) présente une extrémité de dessoudure (22) en forme de tube sur l'extrémité libre de laquelle est formée une ouverture de purge (23) et dans laquelle la fritte hydrophile (24) est positionnée.
- Bouteille de collecte de plasma sanguin selon les revendications 3 ou 4, caractérisée en ce que deux sacs pilotes (20) sont reliés au tube (10) relié au connecteur (9) du point de raccordement (7b, 7c) servant à la prise d'échantillons par un tube de raccordement (21) correspondant et notamment en forme de V.
- Bouteille de collecte de plasma sanguin selon l'une des revendications précédentes, caractérisée en ce qu'un couvercle (11) est fixé ou peut être fixé au goulot (2) et notamment à l'une des plaques de recouvrement (2a) refermant le goulot (2) sur sa face supérieure, et que le couvercle (11) est configuré de telle sorte que, à l'état monté, il enveloppe des sections du tube (10) ou des tubes (10) en saillie par rapport au goulot (2), le protégeant ainsi d'un accès depuis l'extérieur, le couvercle (11) étant notamment configuré de sorte que, à l'état monté, il enveloppe les points de raccordement (7a, 7b ; 7c, 7d) en les protégeant d'un accès depuis l'extérieur.
- Bouteille de collecte de plasma sanguin selon la revendication 6, caractérisée en ce que le bouchon (11) est pourvu d'encoches affectées au tube (10) ou aux tubes (10) et ouvertes en direction du dessous du bouchon, qui est/sont enveloppée(s) par le tube (10) ou les tubes (10) lorsque le bouchon (11) est fixé au goulot, que la face intérieure du bouchon (11) comporte des barres de maintien qui enveloppent et positionnent le tube (10) dépassant du goulot (2) ou les tubes (10) dépassants du goulot (2) lorsque le bouchon (11) est fixé au goulot (2).
- Bouteille de collecte de plasma sanguin selon l'une des revendications 6 à 7, caractérisée en ce qu'un mécanisme d'enclenchement sert à fixer le bouchon (11) au goulot (2) et notamment à la plaque de recouvrement (2a) lorsque le bouchon (11) est enfoncé sur le goulot (2) à partir du haut, le mécanisme d'enclenchement présentant une première position d'encliquetage, dans laquelle le bouchon (11) peut être dévissé du goulot (2), ainsi qu'une deuxième position d'encliquetage, dans laquelle le bouchon (11) est enfoncé plus profondément sur le goulot (2) que dans la première position d'encliquetage et le bouchon (11) ne peut être retiré du goulot (2), le rebord inférieur et ouvert du bouchon présentant des becs d'encliquetage (13) qui, lorsque est enfoncé le bouchon (11) sur le goulot (2), s'engagent dans les barres de maintien formés sur le goulot (2) ainsi que notamment sur le rebord externe de la plaque de recouvrement (2a), sont écartées de façon élastique, puis retournent à leur forme originale en s'accrochant à l'arrière des barres de maintien et en prenant la première position d'encliquetage.
- Bouteille de collecte de plasma sanguin selon la revendication 8 ou 7, caractérisée en ce qu'une barre (14) en saillie verticale est disposée sur le dessus du goulot (2), et notamment de la plaque de recouvrement (2a), et qu'une prise (15) correspondant à la barre (14) est disposée à l'intérieur du bouchon, la première s'engageant dans la seconde lorsque le bouchon (11) est enfoncé sur le goulot (2), et que la barre (14) et la prise (15) présentent des éléments d'encliquetage (16, 17) du mécanisme d'encliquetage qui s'engagent l'un dans l'autre lorsque la deuxième position d'encliquetage est atteinte, la barre (14) étant pourvue d'une ouverture d'arrêt (16) dans laquelle s'engage un élément d'encliquetage (17) prévu du côté réception lorsque la deuxième position d'encliquetage est atteinte.
- Bouteille de collecte de plasma sanguin selon l'une des revendications précédentes, caractérisée en ce que les surfaces latérales du corps de bouteille (2) définissent chacune une zone (3) plate ou légèrement convexe à laquelle se raccordent des zones arrondies vers les surfaces frontales.
- Bouteille de collecte de plasma sanguin selon l'une des revendications précédentes, caractérisée en ce que les surfaces latérales du corps de bouteille (2) définissent chacune une zone (3) plate ou légèrement convexe, la courbure ayant une profondeur maximale de 2 mm, plus précisément de 1,5 mm.
- Bouteille de collecte de plasma sanguin selon les revendications 10 ou 11, caractérisée en ce que les zones plates ou légèrement convexes (3) ont une forme hexagonale dont les faces de base (3a, 3b) sont situées dans les zones de transition entre les surfaces latérales ainsi que le dessus et le dessous du corps de bouteille (1), les zones plates ou légèrement convexes (3) ayant notamment une forme hexagonale régulière de sorte que les coins (E) situés entre les faces de base (3a, 3b) soient positionnés environ à la hauteur centrale du corps de bouteille (1).
- Bouteille de collecte de plasma sanguin selon la revendication 12, caractérisée en ce que les côtés situés entre les faces de base (3a, 3b) des zones hexagonales (3) sont légèrement arrondis.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE201120052056 DE202011052056U1 (de) | 2011-11-22 | 2011-11-22 | Blutplasmasammelflasche |
PCT/EP2012/072764 WO2013076007A1 (fr) | 2011-11-22 | 2012-11-15 | Flacon de collecte de plasma sanguin |
Publications (2)
Publication Number | Publication Date |
---|---|
EP2782543A1 EP2782543A1 (fr) | 2014-10-01 |
EP2782543B1 true EP2782543B1 (fr) | 2015-07-15 |
Family
ID=45557602
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP12790854.9A Not-in-force EP2782543B1 (fr) | 2011-11-22 | 2012-11-15 | Flacon de collecte de plasma sanguin |
Country Status (5)
Country | Link |
---|---|
US (1) | US9381134B2 (fr) |
EP (1) | EP2782543B1 (fr) |
CN (1) | CN203263807U (fr) |
DE (1) | DE202011052056U1 (fr) |
WO (1) | WO2013076007A1 (fr) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TWD168034S (zh) * | 2014-01-14 | 2015-05-21 | Jms股份有限公司 | 凍結保存容器 |
US10959423B2 (en) | 2014-03-31 | 2021-03-30 | Cytiva Sweden Ab | Product and method for cell preservation |
DE202015102323U1 (de) * | 2015-05-06 | 2016-08-09 | Octapharma Plasma Gmbh | Blutplasmasammelflasche |
NL2015473B1 (en) * | 2015-09-21 | 2017-04-19 | Scholle Ipn Ip Bv | A spouted pouch adapted to be filled with a flowable product. |
CN109152698B (zh) | 2016-05-16 | 2022-07-01 | 美国血液技术公司 | 无密封件的血浆瓶及其顶盖 |
US11648179B2 (en) | 2016-05-16 | 2023-05-16 | Haemonetics Corporation | Sealer-less plasma bottle and top for same |
DE202016104900U1 (de) * | 2016-09-06 | 2016-10-07 | Heinz Meise Gmbh | Blutplasma-Flasche |
EP3796884B1 (fr) * | 2018-05-22 | 2024-04-17 | Haemonetics Corporation | Flacon de plasma sans scellement et sa partie supérieure |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4568345A (en) | 1982-09-13 | 1986-02-04 | Baxter Travenol Laboratories, Inc. | Container and associated cap assembly for plasma collection and the like |
US5132026A (en) * | 1991-03-21 | 1992-07-21 | Alpha Therapeutic Corporation | Blood plasma collection system |
US5728086A (en) * | 1996-07-30 | 1998-03-17 | Bracco Diagnostics, Inc. | Universal flexible plastic container with multiple access ports |
EP1002512A3 (fr) * | 1998-11-19 | 2001-01-24 | Bracco International B.V. | Récipient souple pour conserver et distribuer des liquides |
US20100030181A1 (en) * | 2006-11-30 | 2010-02-04 | Kevin Helle | Dual-lumen needle |
DE202007012912U1 (de) | 2007-09-14 | 2007-12-06 | Heinz Meise Gmbh | Blutplasma-Behälter |
DE202009001068U1 (de) * | 2009-01-28 | 2009-04-09 | Heinz Meise Gmbh | Blutplasma-Behälter |
DE202010012728U1 (de) * | 2010-09-22 | 2011-11-29 | Deutsche Gesellschaft für Humanplasma mbH | Blutplasmasammelflasche |
-
2011
- 2011-11-22 DE DE201120052056 patent/DE202011052056U1/de not_active Expired - Lifetime
-
2012
- 2012-11-15 EP EP12790854.9A patent/EP2782543B1/fr not_active Not-in-force
- 2012-11-15 WO PCT/EP2012/072764 patent/WO2013076007A1/fr active Application Filing
- 2012-11-15 US US14/360,146 patent/US9381134B2/en active Active
- 2012-11-22 CN CN2012207573284U patent/CN203263807U/zh not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP2782543A1 (fr) | 2014-10-01 |
CN203263807U (zh) | 2013-11-06 |
US9381134B2 (en) | 2016-07-05 |
WO2013076007A1 (fr) | 2013-05-30 |
DE202011052056U1 (de) | 2011-12-30 |
US20140324011A1 (en) | 2014-10-30 |
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