EP2861557A1 - A method for the preparation of 3-amino-n-cyclopropyl-2-hydroxyl-hexanamide - Google Patents

A method for the preparation of 3-amino-n-cyclopropyl-2-hydroxyl-hexanamide

Info

Publication number
EP2861557A1
EP2861557A1 EP13727945.1A EP13727945A EP2861557A1 EP 2861557 A1 EP2861557 A1 EP 2861557A1 EP 13727945 A EP13727945 A EP 13727945A EP 2861557 A1 EP2861557 A1 EP 2861557A1
Authority
EP
European Patent Office
Prior art keywords
amino
hydroxyl
acid
carboxylic acid
alkyl ester
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP13727945.1A
Other languages
German (de)
English (en)
French (fr)
Inventor
Bangping LIN
Zhongmei WANG
Bin Guo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Pharmaceutica NV
Original Assignee
Janssen Pharmaceutica NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CN2012101939234A external-priority patent/CN102702016A/zh
Application filed by Janssen Pharmaceutica NV filed Critical Janssen Pharmaceutica NV
Publication of EP2861557A1 publication Critical patent/EP2861557A1/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
EP13727945.1A 2012-06-13 2013-06-12 A method for the preparation of 3-amino-n-cyclopropyl-2-hydroxyl-hexanamide Withdrawn EP2861557A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN2012101939234A CN102702016A (zh) 2012-06-13 2012-06-13 一种3-氨基-n-环丙基-2-羟基己酰胺的制备方法
CN2012082591 2012-10-08
PCT/EP2013/062121 WO2013186248A1 (en) 2012-06-13 2013-06-12 A method for the preparation of 3-amino-n-cyclopropyl-2-hydroxyl-hexanamide

Publications (1)

Publication Number Publication Date
EP2861557A1 true EP2861557A1 (en) 2015-04-22

Family

ID=48579124

Family Applications (1)

Application Number Title Priority Date Filing Date
EP13727945.1A Withdrawn EP2861557A1 (en) 2012-06-13 2013-06-12 A method for the preparation of 3-amino-n-cyclopropyl-2-hydroxyl-hexanamide

Country Status (5)

Country Link
EP (1) EP2861557A1 (pt)
CN (1) CN104812733A (pt)
BR (1) BR112014030870A2 (pt)
IN (1) IN2014MN02533A (pt)
WO (1) WO2013186248A1 (pt)

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2004298498B2 (en) 2003-12-11 2008-09-11 Schering Corporation Inhibitors of hepatitis C virus NS3/NS4a serine protease
US8399615B2 (en) * 2005-08-19 2013-03-19 Vertex Pharmaceuticals Incorporated Processes and intermediates
EP1993993A1 (en) 2006-03-16 2008-11-26 Vertex Pharmaceuticals Incorporated Processes and intermediates for preparing steric compounds
WO2007138928A1 (ja) * 2006-05-26 2007-12-06 Kaneka Corporation 光学活性３－アミノ－２－ヒドロキシプロピオン酸シクロプロピルアミド誘導体およびその塩の製造方法
US20080108632A1 (en) * 2006-11-02 2008-05-08 Taigen Biotechnology Co., Ltd. Hcv protease inhibitors
CN101186587B (zh) * 2006-11-16 2010-04-21 凯莱英医药化学（阜新）技术有限公司 一种β-氨基酸的衍生物合成方法及其中间产物
CN101691338B (zh) * 2009-08-26 2013-08-14 凯莱英生命科学技术(天津)有限公司 一种手性环氧化合物的合成方法及其中间产物与最终产物

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See references of WO2013186248A1 *

Also Published As

Publication number Publication date
IN2014MN02533A (pt) 2015-07-24
WO2013186248A1 (en) 2013-12-19
CN104812733A (zh) 2015-07-29
BR112014030870A2 (pt) 2017-06-27

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