EP2703335A1 - Vorrichtung zur entstaubung durch luftvorhangsisolierung und selbstzirkulationsreinigung - Google Patents

Vorrichtung zur entstaubung durch luftvorhangsisolierung und selbstzirkulationsreinigung Download PDF

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Publication number
EP2703335A1
EP2703335A1 EP12781974.6A EP12781974A EP2703335A1 EP 2703335 A1 EP2703335 A1 EP 2703335A1 EP 12781974 A EP12781974 A EP 12781974A EP 2703335 A1 EP2703335 A1 EP 2703335A1
Authority
EP
European Patent Office
Prior art keywords
cabin
main isolation
wall
isolation cabin
inlet
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP12781974.6A
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English (en)
French (fr)
Other versions
EP2703335A4 (de
Inventor
Dandou FAN
Xiaoyong Yu
Qiang Li
Wenqing XIAO
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zhejiang Vacin Bio-pharmaceutical Ltd
Zhejiang Vacin Bio Pharmaceutical Ltd
Original Assignee
Zhejiang Vacin Bio-pharmaceutical Ltd
Zhejiang Vacin Bio Pharmaceutical Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zhejiang Vacin Bio-pharmaceutical Ltd, Zhejiang Vacin Bio Pharmaceutical Ltd filed Critical Zhejiang Vacin Bio-pharmaceutical Ltd
Publication of EP2703335A1 publication Critical patent/EP2703335A1/de
Publication of EP2703335A4 publication Critical patent/EP2703335A4/de
Withdrawn legal-status Critical Current

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    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F24—HEATING; RANGES; VENTILATING
    • F24F—AIR-CONDITIONING; AIR-HUMIDIFICATION; VENTILATION; USE OF AIR CURRENTS FOR SCREENING
    • F24F9/00—Use of air currents for screening, e.g. air curtains
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F24—HEATING; RANGES; VENTILATING
    • F24F—AIR-CONDITIONING; AIR-HUMIDIFICATION; VENTILATION; USE OF AIR CURRENTS FOR SCREENING
    • F24F3/00—Air-conditioning systems in which conditioned primary air is supplied from one or more central stations to distributing units in the rooms or spaces where it may receive secondary treatment; Apparatus specially designed for such systems
    • F24F3/12—Air-conditioning systems in which conditioned primary air is supplied from one or more central stations to distributing units in the rooms or spaces where it may receive secondary treatment; Apparatus specially designed for such systems characterised by the treatment of the air otherwise than by heating and cooling
    • F24F3/16—Air-conditioning systems in which conditioned primary air is supplied from one or more central stations to distributing units in the rooms or spaces where it may receive secondary treatment; Apparatus specially designed for such systems characterised by the treatment of the air otherwise than by heating and cooling by purification, e.g. by filtering; by sterilisation; by ozonisation
    • F24F3/163—Clean air work stations, i.e. selected areas within a space which filtered air is passed

Definitions

  • the invention relates to a cleaning and isolation facility for pharmaceutical processing equipment, in particular to a device for dust removal through air curtain isolation and self-circulation purification, applied in a pharmaceutical clean area (i.e., pharmaceutical clean room) to be able to guarantee sterile unidirectional flow inside the isolation facility and also prevent dust and aerosol produced by the pharmaceutical processing equipment during running from resulting in pollution and interference to the environment of both the processing area and the whole clean area.
  • a pharmaceutical clean area i.e., pharmaceutical clean room
  • the capping machine is equipment for sealing drug containers, which have been filled and stoppered or have been freeze-dried and corked, by an aluminum cap and aluminum plastics. After a drug container has been filled and stoppered but before capped and sealed, the connection between the rubber stopper and the bottleneck is in an Incomplete Seal status, there is a possibility of loosing even bouncing of the stopper.
  • the capping machine in a capping workshop during capping will produce a lot of suspended aluminum scraps, glass chips, aerosol and other kinds of dust, which are difficult to detect.
  • Such dust produced by the capping machine constitutes a serious pollution threat to the sterile status of the capping workshop area. Meanwhile, such dust will spread around through the purification and air-conditioning system of the whole clean area, thereby resulting in extensive pollution to the environment of the whole clean area for pharmaceutical manufacturing and interference to the purification and air-conditioning system of the clean area.
  • the Minimum Requirement on capping of non-terminally sterilized products in Chinese GMP (Good Manufacturing Practice) Version 1998 is Grade 100,000 (Grade D).
  • the GMP Version 2010 revised by the State Food and Drug Administration specifies that capping of non-terminally sterilized products must be done in a Grade A environment under Grade B background.
  • the requirements in the new version of GMP cannot be met due to the pollution of aluminum scraps, glass chips and aerosol to the capping workshop.
  • most pharmaceutical enterprises place the capping machine in a Grade 100 laminar hood in a Grade 100,000 capping workshop for running, as a result, the cleanness of the capping area is difficult to meet the standard requirements.
  • Dust, particles and aerosol may also be produced during other procedures of pharmaceutical manufacturing, for example, during the processing and sub-packaging of bacterial and virus species, contraceptives, antineoplastic drugs, radiochemicals and highly toxic products, in addition to the foregoing capping and sealing procedures of pharmaceutical manufacturing, thereby resulting in pollution and interference to operators and the environment of the whole clean area. Therefore, the prior art has problems and deficiencies that the cleanness of the environment of the pharmaceutical processing area is difficult to meet the standard requirements.
  • a device for dust removal through air curtain isolation and self-circulation purification, comprises a material input transferring cabin;
  • a main isolation cabin having a front wall, a back wall, a left wall, and a right wall, for placing and isolating a processing equipment which is placed inside the main isolation cabin, each wall has a top and a bottom, the main isolation cabin being connected to the material input transferring cabin through a material inlet that is formed on a wall between the main input transferring cabin and the main isolation cabin; a material output transferring cabin connected to the main isolation cabin through a material outlet that is formed on a wall between the main isolation cabin and the material output transferring cabin; and
  • control cabinet containing an automatic control device for adjusting, displaying, and recording air volume, pressure differential, and a number of suspended particles in the main isolation cabin, the material input transferring cabin, and the material output transferring cabin;
  • the main isolation cabin is a sealed cabin surrounded by walls, the material input transferring cabin and the material output transferring cabin are respectively disposed on left side and right side of the main isolation cabin, a material input hole is formed on a left wall of the material input transferring cabin, a material output hole is formed on a right wall of the material output transferring cabin; a first laminar flow filtering hood, a second laminar flow filtering hood and a third laminar flow filtering hood connect to and seal respectively a top of the main isolation cabin, a top of the material input transferring cabin, and a top of the material output transferring cabin, the first laminar flow filtering hood has an air supply surface, a first air inlet is formed on a sidewall of the second laminar flow filtering hood and a second air inlet is formed on a sidewall of the third laminar flow filtering hood, a first air passage is formed between a bottom of the material input transferring cabin and the ground, a second air passage is formed
  • a self-circulation air pipe with a lower end and an upper end is vertically attached to the front wall of the main isolation cabin, a waste container with an open top and a lower interface is placed inside the main isolation cabin below the processing equipment, the lower interface of the waste container enables the main isolation cabin to communicate with the lower end of the self-circulation air pipe;
  • a plurality of filters and a fan are placed inside the self circulation air pipe, the upper end of the self-circulation air pipe connects to the first laminar flow filtering hood, and the lower end of the self-circulation air pipe connects to the lower interface of the waste container;
  • an inlet reduction spreader plate with a top portion and a lower portion and an outlet reduction spreader plate with a top portion are installed inside the main isolation cabin in parallel with left and right walls of the main isolation cabin respectively, a first gap interlayer is placed between the inlet reduction spreader plate and the left wall of the main isolation cabin forming an inlet spreader air curtain passage, a second gap interlayer is placed between the outlet reduction spreader plate and the right wall of the main isolation cabin forming an outlet spreader air curtain passage, the top portions of the inlet reduction spreader plate and the outlet reduction spreader plate are close to the air supply surface of the laminar flow filtering hood, the lower portions of the inlet reduction spreader plate and the outlet reduction spreader plate are respectively provided with a reduction plate inlet and a reduction plate outlet at positions corresponding to the material inlet and the material outlet.
  • each wall of the main isolation cabin has a bottom and a plastic plate sealing off the bottom of the four walls to isolate the main isolation cabin from the ground, and, the air passages are formed between the lower portions of the walls of the material input transferring cabin and the material output transferring cabin, excepting the wall adjacent to the main isolation cabin, and the ground.
  • the filters in the self-circulation air pipe comprise a plug-board coarse-efficiency filter and a plug-board medium-efficiency filter.
  • the waste container has a funnel shape and a lower portion for collecting dust of large particles.
  • a sealed door and a glove box are disposed on the back wall of the main isolation cabin.
  • each of the front wall, back wall, left wall, and right wall of the main isolation cabin are sealingly attached to the first laminar flow filtering hood, and only the bottom of the front wall and back wall of the main isolation cabin are sealingly attached to a workbench.
  • edges of the inlet reduction spreader plate and the outlet reduction spreader plate are respectively sealingly attached to the front wall and back wall of the main isolation cabin.
  • all the walls are made from transparent glass or transparent organic glass sheets, and the edge of each wall comprises a metal frame.
  • another device for dust removal through air curtain isolation and self-circulation purification, comprising a material input transferring cabin with a bottom, a main isolation cabin, with a center, a front wall, a back wall, a left wall, and a right wall, each wall has a top and a bottom, attached to the material input transferring cabin and containing an processing equipment, a material output transferring cabin, with a bottom, attached to the main isolation cabin, and a control cabinet attached to the material output transferring cabin;
  • the main isolation cabin is a sealed cabin surrounded by walls
  • the material input transferring cabin is disposed on the left side of the main isolation cabin
  • a material input hole is formed on a left wall of the material input transferring cabin
  • a material inlet is formed on a wall between the main isolation cabin and the material input transferring cabin and enables communication between the main isolation cabin and the material input transferring cabin;
  • the material output transferring cabin is disposed on right side of the main isolation cabin, a material output hole is formed on a right wall of the material output transferring cabin, and a material outlet is formed on a wall between the main isolation cabin and the material output transferring cabin and enables communication between the main isolation cabin and the material output transferring cabin;
  • control cabinet is an automatic control device for adjusting, displaying, and recording air volume, pressure difference and a number of suspended particles in the main isolation cabin, the material input transferring cabin, and the material output transferring cabin;
  • all the walls are made from transparent glass or transparent organic glass sheets, and the edge of each wall comprises a metal frame;
  • a first laminar flow filtering hood, a second high-efficiency laminar flow filtering hood and a third high-efficiency laminar flow filtering hood are respectively sealingly attached to top of the main isolation cabin, the material input transferring cabin and the material output transferring cabin, an air inlet is formed on each of the second filtering laminar high-efficiency flow hood and the third high-efficiency laminar flow filtering hood, and a first air passage is formed between the bottom of the material input transferring cabin and the ground, a second air passage is formed between the bottom of the material output transferring cabin and the ground;
  • the main isolation cabin has four walls, each wall has a bottom, and a plastic plate sealing off the bottoms of the four walls to isolate the main isolation cabin from the ground, and, the air passages are formed between the lower portions of the walls of the material input transferring cabin and the material output transferring cabin, excepting the wall adjacent to the main isolation cabin, and the ground;
  • the processing equipment is disposed in the center of the main isolation cabin, a self-circulation air pipe, with a middle, a lower end, and an upper end, is vertically attached to the front wall of the main isolation cabin, a waste container with a top opening is disposed inside the main isolation cabin and below the processing equipment, the waste container, having a caisson shape lower portion for collecting dust of large particles, is provided with a lower interface facing the front wall of the main isolation cabin and allowing communication with a lower end of the self-circulation air pipe;
  • the self-circulation air pipe is provided with a plurality of filters and a fan placed respectively at the middle and the upper end of the self-circulation air pipe, the self-circulation air pipe communicates with the first high-efficiency laminar flow filtering hood, and the lower end of the self-circulation air pipe is in communication with the lower interface of the waste container, a sealed door and a glove box are disposed on the back wall of the main isolation cabin;
  • the top of each wall of the main isolation cabin is sealing attached to the first high-efficiency laminar flow filtering hood, and the bottoms of the front wall and back wall of the main isolation cabin are stealing attached to a workbench, the top of each of the walls adjacent to the main isolation cabin, the material input transferring cabin and the material output transferring cabin is sealing attached to the first high-efficiency laminar flow filtering hood, but the bottoms of the walls are not sealing attached to a workbench and without providing with the material inlet and the material outlet;
  • an inlet reduction spreader plate and an outlet reduction spreader plate are disposed inside the main isolation cabin in parallel, respectively, with the left wall and the right wall of the main isolation cabin, a first gap interlayer is formed between the inlet reduction spreader plate and the left wall of the main isolation cabin and a second gap interlayer is formed between the outlet reduction spreader plate and the right wall of the main isolation cabin, the first gap interlayer and the second gap interlayer form an inlet spreader air curtain passage and an outlet spreader air curtain passage, edges of the inlet reduction spreader plate and the outlet reduction spreader plate are respectively sealing attached to the front wall and back wall of the main isolation cabin, top portions of the inlet reduction spreader plate and the outlet reduction spreader plate are adjacent to an air supply surface on the high-efficiency laminar flow filtering hood, and lower portions of the inlet reduction spreader plate and the outlet reduction spreader plate are respectively provided with a reduction plate inlet and a reduction plate outlet at positions corresponding to the material inlet and the material outlet;
  • the processing equipment is placed inside the main isolation cabin; and the material is fed into the main isolation cabin through the material input hole, the material input transferring cabin, the material input hole, the inlet spreader air curtain passage and the reduction plate inlet, processed by the processing equipment, and then output from the reduction plate outlet, the outlet spreader air curtain passage and the material outlet through the material output transferring cabin and the material output hole.
  • Dust-contained air inside the main isolation cabin is pumped into the self-circulation air pipe by the fan in the first laminar flow filtering hood, and then filtered by the coarse-efficiency, medium-efficiency and high-efficiency filters to form a vertical laminar flow below the first laminar flow filtering hood, most air enters into the working area of the processing equipment inside the main isolation cabin, a small amount of air forms a vertically downwards laminar flow in the inlet spreader air curtain passage and the outlet spreader air curtain passage due to the spreading of the inlet reduction spreader plate and the outlet reduction spreader plate to form a spreader air curtain, and, the clean air from the spreader air curtain flows downward and is pumped into the main isolation cabin from the reduction plate inlet and a reduction plate outlet, to compensate the spreading loss of the total air supply amount from the first laminar flow filtering hood on the top of the main isolation cabin.
  • the glove box and the sealed door are arranged such that, when the processing equipment needs manual intervention, the operator may perform intervention to the processing equipment in the main isolation cabin through rubber gloves in the glove box; and at the end of processing, the operator may open the sealed door to clean, sterilize and maintain the main isolation cabin and the equipment therein.
  • capping may be done in a Grade A air supply environment under Grade C or D background, and the Grade A air supply environment should at least be in accordance with the static requirement of the Grade A area".
  • the number of the material input transferring cabins and the material output transferring cabins in the invention may be increased or decrease; or even, the material input transferring cabins and the material output transferring cabins may be integrated, depending on the process requirement.
  • a self-circulation purification device formed of self-circulation air pipes with a plug-board coarse-efficiency filter and a plug-board medium-efficiency filter is disposed in the main isolation cabin, and an airflow cleaning air curtain formed of an inlet airflow air curtain passage and an outlet airflow air curtain passage is respectively disposed between the main isolation cabin and the material input transferring cabin and also between the main isolation cabin and the material output transferring cabin, the invention overcomes the problems and deficiencies in the prior art that the cleanness of the environment of the pharmaceutical processing area is difficult to meet the standard requirements.
  • the device for dust removal through air curtain isolation and self-circulation purification isolates dust produced by the processing equipment in the area where it is produced and removes it at the moment when it is produced by means of air curtain isolation and self-circulation purification, thereby avoiding the spreading of dust resulting in pollution and interference to the environment of both the processing area and the whole clean area and facilitating the cleanness of the pharmaceutical processing environment to meet the standard requirements in the Chinese GMP Version 2010.
  • the device for dust removal through air curtain isolation and self-circulation purification comprises a material input transferring cabin 1, a main isolation cabin 2 for placing and isolating a processing equipment 6, a material output transferring cabin 3 and a control cabinet 7.
  • the main isolation cabin 2 is a sealed cabin surrounded by walls, the material input transferring cabin 1 and the material output transferring cabin 3 are respectively disposed on left side and right side of the main isolation cabin 2, the main isolation cabin 2 is connected to the material input transferring cabin 1 through a material inlet 11 that is formed on a wall between the main input transferring cabin 1 and the main isolation cabin 2, and the main isolation cabin 2 is connected to the material output transferring cabin 3 through a material outlet 31 that is formed on a wall between the main isolation cabin and the material output transferring cabin.
  • the material input transferring cabin 1 is connected to other external facilities through a material input hole 111 formed on a left wall of the material input transferring cabin 1, and the material output transferring cabin 3 is connected to outside through a material output hole 311 formed on a right wall of the material output transferring cabin 3.
  • the control cabinet 7 contains an automatic control device for adjusting, displaying, and recording air volume, pressure differential, and a number of suspended particles in the main isolation cabin 2, the material input transferring cabin 1 and the material output transferring cabin 3.
  • All the walls are made from transparent glass or transparent organic glass sheets, and the edge of each wall comprises a metal frame.
  • a first laminar flow filtering hood 5, a second laminar flow filtering hood 51 and a third laminar flow filtering hood 52 connect to and seal respectively a top of the main isolation cabin 2, a top of the material input transferring cabin 1 and a top of the material output transferring cabin 3,
  • the first laminar flow filtering hood has an air supply surface
  • a first air inlet is formed on a sidewall of the second laminar flow filtering hood 51
  • a second air inlet is formed on a sidewall of the third laminar flow filtering hood 52
  • each wall of the main isolation cabin 2 has a bottom and a plastic plate sealing off the bottom of the four walls to isolate the main isolation cabin 2 from the ground, and, the air passages are formed between the lower portions of the walls of the material input transferring cabin 1 and the material output transferring cabin 3, excepting the wall adjacent to the main isolation cabin 2, and the ground.
  • the processing equipment 6 is placed inside the main isolation cabin 2, a waste container 23 with an open top and a lower interface is placed inside the main isolation cabin 2 below the processing equipment 6, the waste container 23 has a funnel shape and a lower portion for collecting dust of large particles, the lower interface 23a of the waste container enables the main isolation cabin 2 to communicate with the lower end of the self-circulation air pipe 21, and the lower interface 23a of the waste container 23 is enabled to pass through the front wall of the main isolation cabin 2 to communicate with the lower end of the self-circulation air pipe 21.
  • a plurality of filters and a fan are placed inside the self circulation air pipe 21, the filters in the self-circulation air pipe 21 comprise a plug-board coarse-efficiency filter 24 and a plug-board medium-efficiency filter 25, the upper end of the self-circulation air pipe 21 connects to the first laminar flow filtering hood 5, and the lower end of the self-circulation air pipe 21 connects to the lower interface 23a of the waste container 23; and a sealed door 42 and a glove box 41 are disposed on the back wall of the main isolation cabin 2.
  • each of the front wall and back wall of the main isolation cabin 2 is sealingly attached to the first laminar flow filtering hood 5, and only the bottom of the front wall and back wall of the main isolation cabin 2 are sealingly attached to a workbench; the top of each of the walls of the main isolation cabin 2 adjacent to the material input transferring cabin 1 and the material output transferring cabin 3 is sealingly attached to the first laminar flow filtering hood 5, the bottom of the walls of the main isolation cabin 2 are not sealingly attached to a workbench, and the material inlet 11 and the material outlet 31 are respectively formed on the walls.
  • An inlet reduction spreader plate 12 with a top portion and a lower portion and an outlet reduction spreader plate 32 with a top portion are installed inside the main isolation cabin 2 in parallel with left and right walls of the main isolation cabin 2 respectively, a first gap interlayer is placed between the inlet reduction spreader plate 12 and the left wall of the main isolation cabin 2 forming an inlet spreader air curtain passage, and a second gap interlayer is placed between the outlet reduction spreader plate 32 and the right wall of the main isolation cabin 2 forming an outlet spreader air curtain passage; the vertical edge of the inlet reduction spreader plate 12 and the outlet reduction spreader plate 32 is sealingly connected to the front wall and back wall of the main isolation cabin 2, respectively; the top portions of the inlet reduction spreader plate 12 and the outlet reduction spreader plate 32 are close to the air supply surface of the laminar flow filtering hood 5, and the lower portions of the inlet reduction spreader plate 12 and the outlet reduction spreader plate 32 are respectively provided with a reduction plate inlet 112 and a reduction plate outlet 312 at positions corresponding to the material
  • the processing equipment 6 is placed inside the main isolation cabin 2; and the material is fed into the main isolation cabin 2 through the material input hole 111, the material input transferring cabin 1, the material input hole 11, the inlet spreader air curtain passage 26 and the reduction plate inlet 112, processed by the processing equipment 6, and then output from the reduction plate outlet 312, the outlet spreader air curtain passage 27 and the material outlet 31 through the material output transferring cabin 3 and the material output hole 311.
  • Dust-contained air inside the main isolation cabin 2 is pumped into the self-circulation air pipe 21 by the fan in the first laminar flow filtering hood 5, and then filtered by the coarse-efficiency, medium-efficiency and high-efficiency filters to form a vertical laminar flow below the first laminar flow filtering hood 5, most air enters into the working area of the processing equipment 6 inside the main isolation cabin 2, a small amount of air forms a vertically downwards laminar flow in the inlet spreader air curtain passage 26 and the outlet spreader air curtain passage 27 due to the spreading of the inlet reduction spreader plate 12 and the outlet reduction spreader plate 32 to form a spreader air curtain, and, the clean air from the spreader air curtain flows downward and is pumped into the main isolation cabin from the reduction plate inlet 112 and a reduction plate outlet 312, to compensate the spreading loss of the total air supply amount from the first laminar flow filtering hood 5 on the top of the main isolation cabin 2.
  • the glove box 41 and the sealed door 42 are arranged such that, when the processing equipment 6 needs manual intervention, the operator may perform intervention to the processing equipment 6 in the main isolation cabin 2 through rubber gloves in the glove box 41; and at the end of processing, the operator may open the sealed door 42 to clean, sterilize and maintain the main isolation cabin 2 and the equipment therein.

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  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Combustion & Propulsion (AREA)
  • Mechanical Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Ventilation (AREA)
EP12781974.6A 2011-05-10 2012-05-07 Vorrichtung zur entstaubung durch luftvorhangsisolierung und selbstzirkulationsreinigung Withdrawn EP2703335A4 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201110132849A CN102219174B (zh) 2011-05-10 2011-05-10 风幕隔离和自循环净化的消除尘屑装置
PCT/CN2012/000603 WO2012152062A1 (zh) 2011-05-10 2012-05-07 风幕隔离和自循环净化的消除尘屑装置

Publications (2)

Publication Number Publication Date
EP2703335A1 true EP2703335A1 (de) 2014-03-05
EP2703335A4 EP2703335A4 (de) 2015-03-11

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EP12781974.6A Withdrawn EP2703335A4 (de) 2011-05-10 2012-05-07 Vorrichtung zur entstaubung durch luftvorhangsisolierung und selbstzirkulationsreinigung

Country Status (4)

Country Link
US (1) US20130284028A1 (de)
EP (1) EP2703335A4 (de)
CN (1) CN102219174B (de)
WO (1) WO2012152062A1 (de)

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KR20180052820A (ko) * 2016-11-10 2018-05-21 엘지전자 주식회사 에어 워시 장치

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CN102530324A (zh) * 2011-11-25 2012-07-04 杭州泰林生物技术设备有限公司 一种无菌粉针分装生产线的净化隔离装置
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CN111573604B (zh) * 2019-09-05 2024-04-16 深圳艾欣达伟医药科技有限公司 Ast-3424注射液的配制灌注加塞压盖系统及方法
CN111805785B (zh) * 2020-07-29 2021-11-30 泉州市英花建筑物清洁服务有限公司 改善除尘率的水幕除尘柜
CN112283839A (zh) * 2020-11-27 2021-01-29 伍海峰 移动式生物医疗隔离舱
CN115143572B (zh) * 2022-08-31 2022-11-22 苏州斐森尔净化科技有限公司 一种用于vhp传递舱的无菌送风装置
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CN107255904A (zh) * 2017-07-24 2017-10-17 亚翔系统集成科技（苏州）股份有限公司 一种开放式光罩存储装置

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WO2012152062A1 (zh) 2012-11-15
CN102219174A (zh) 2011-10-19
CN102219174B (zh) 2012-10-17
EP2703335A4 (de) 2015-03-11

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