EP2637684A4 - Gepufferte ophthalmische zusammensetzungen und verwendungsverfahren dafür - Google Patents

Gepufferte ophthalmische zusammensetzungen und verwendungsverfahren dafür

Info

Publication number
EP2637684A4
EP2637684A4 EP11840613.1A EP11840613A EP2637684A4 EP 2637684 A4 EP2637684 A4 EP 2637684A4 EP 11840613 A EP11840613 A EP 11840613A EP 2637684 A4 EP2637684 A4 EP 2637684A4
Authority
EP
European Patent Office
Prior art keywords
methods
ophthalmic compositions
buffered ophthalmic
buffered
compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP11840613.1A
Other languages
English (en)
French (fr)
Other versions
EP2637684A2 (de
Inventor
Tamar Tennenbaum
Liora Braiman-Wiksman
Yuval Sagiv
Ofra Levy-Hacham
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ARAVA BIO-TECH LTD.
Original Assignee
Healor Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Healor Ltd filed Critical Healor Ltd
Priority to EP15167715.0A priority Critical patent/EP2944319A1/de
Publication of EP2637684A2 publication Critical patent/EP2637684A2/de
Publication of EP2637684A4 publication Critical patent/EP2637684A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Organic Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
EP11840613.1A 2010-11-08 2011-11-08 Gepufferte ophthalmische zusammensetzungen und verwendungsverfahren dafür Withdrawn EP2637684A4 (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP15167715.0A EP2944319A1 (de) 2010-11-08 2011-11-08 Ophthalmische gepufferte zusammensetzungen und verwendung davon

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US41146410P 2010-11-08 2010-11-08
US41146610P 2010-11-08 2010-11-08
PCT/IL2011/000866 WO2012063237A2 (en) 2010-11-08 2011-11-08 Buffered ophthalmic compositions and methods of use thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
EP15167715.0A Division EP2944319A1 (de) 2010-11-08 2011-11-08 Ophthalmische gepufferte zusammensetzungen und verwendung davon

Publications (2)

Publication Number Publication Date
EP2637684A2 EP2637684A2 (de) 2013-09-18
EP2637684A4 true EP2637684A4 (de) 2014-05-07

Family

ID=46051349

Family Applications (2)

Application Number Title Priority Date Filing Date
EP11840613.1A Withdrawn EP2637684A4 (de) 2010-11-08 2011-11-08 Gepufferte ophthalmische zusammensetzungen und verwendungsverfahren dafür
EP15167715.0A Withdrawn EP2944319A1 (de) 2010-11-08 2011-11-08 Ophthalmische gepufferte zusammensetzungen und verwendung davon

Family Applications After (1)

Application Number Title Priority Date Filing Date
EP15167715.0A Withdrawn EP2944319A1 (de) 2010-11-08 2011-11-08 Ophthalmische gepufferte zusammensetzungen und verwendung davon

Country Status (8)

Country Link
US (2) US20120264681A1 (de)
EP (2) EP2637684A4 (de)
JP (1) JP2013543862A (de)
CN (2) CN103249429A (de)
AU (1) AU2011327785A1 (de)
CA (1) CA2812164A1 (de)
RU (1) RU2013117209A (de)
WO (1) WO2012063237A2 (de)

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US8450344B2 (en) 2008-07-25 2013-05-28 Aerie Pharmaceuticals, Inc. Beta- and gamma-amino-isoquinoline amide compounds and substituted benzamide compounds
ES2834451T3 (es) 2009-05-01 2021-06-17 Aerie Pharmaceuticals Inc Inhibidores de mecanismo doble para el tratamiento de enfermedades
SG187770A1 (en) 2010-08-12 2013-03-28 Univ Nanyang Tech A liposomal formulation for ocular drug delivery
EP2637684A4 (de) 2010-11-08 2014-05-07 Healor Ltd Gepufferte ophthalmische zusammensetzungen und verwendungsverfahren dafür
US20130296250A1 (en) * 2011-01-11 2013-11-07 Healor Ltd. Method for treatment of psoriasis
PL2968468T3 (pl) 2013-03-13 2021-12-20 Buzzard Pharmaceuticals AB Preparaty chimerycznej cytokiny do dostarczania do oka
EP2976080B1 (de) 2013-03-15 2019-12-25 Aerie Pharmaceuticals, Inc. Konjugate von isoquinolinverbindungen und prostaglandinen
CN105377285B (zh) * 2013-04-30 2020-04-21 南加利福尼亚大学 通过血管紧缩素肽的加速的眼睛损伤的治愈
US20150141328A1 (en) * 2013-11-18 2015-05-21 The Schepens Eye Research Institute Stimulation of human meibomian gland function
US9956195B2 (en) 2014-01-07 2018-05-01 Nanyang Technological University Stable liposomal formulations for ocular drug delivery
US9463201B2 (en) 2014-10-19 2016-10-11 M.G. Therapeutics Ltd Compositions and methods for the treatment of meibomian gland dysfunction
US10406208B2 (en) 2014-10-22 2019-09-10 G-Treebnt Co., Ltd. Composition containing thymosin beta 4, and pharmaceutical formulation comprising same
EP3011959A1 (de) 2014-10-23 2016-04-27 Santen SAS Quaternäre Ammoniumverbindung zur Verwendung als Proteinkinase-C-Alpha-Hemmer
CN104940904A (zh) * 2015-05-27 2015-09-30 北京爱特普科技有限公司 一种腔体粘膜微生态调节剂及其制备方法
US9867868B2 (en) * 2015-08-18 2018-01-16 G-Treebnt Co., Ltd. Pharmaceutical composition for treating or preventing corneal wound comprising thymosin β4 and citric acid
KR20170021667A (ko) * 2015-08-18 2017-02-28 주식회사 지트리비앤티 티모신 β4를 유효성분으로 포함하는 신경영양성각막염 치료용 조성물
CN108472312A (zh) 2015-09-28 2018-08-31 阿祖拉眼科有限公司 用于增加睑板腺脂质分泌物的含硫醇及二硫化物的药剂
MA44676A (fr) 2016-04-14 2019-02-20 Azura Ophthalmics Ltd Compositions de disulfure de sélénium destinées à être utilisées dans le traitement du dysfonctionnement de la glande de meibomius
JP6943707B2 (ja) * 2016-08-23 2021-10-06 積水化学工業株式会社 水溶性樹脂組成物及び水溶性樹脂フィルム
MX2019002396A (es) 2016-08-31 2019-07-08 Aerie Pharmaceuticals Inc Composiciones oftalmicas.
US10918699B2 (en) * 2017-03-22 2021-02-16 Michael C. Struck Therapeutic treatment for neurotrophic keratopathy
JP2020515583A (ja) 2017-03-31 2020-05-28 アエリエ ファーマシューティカルズ インコーポレイテッド アリールシクロプロピル−アミノ−イソキノリニルアミド化合物
MA50414A (fr) 2017-10-19 2020-08-26 Mona E Buice Composition à usage topique pour la cicatrisation améliorée des plaies ouvertes
AU2019337703B2 (en) 2018-09-14 2023-02-02 Aerie Pharmaceuticals, Inc. Aryl cyclopropyl-amino-isoquinolinyl amide compounds
JP2020075918A (ja) * 2018-11-02 2020-05-21 千寿製薬株式会社 角膜上皮創傷治癒促進用の眼科用組成物
US20210379161A1 (en) * 2019-02-20 2021-12-09 Eleos Pharmaceuticals, Llc Topical composition for improved healing of ocular ailments
US10814001B1 (en) * 2019-05-06 2020-10-27 Rvl Pharmaceuticals, Inc. Oxymetazoline compositions
EP4087655A4 (de) 2020-01-10 2024-02-21 Azura Ophthalmics Ltd Anweisungen für zusammensetzung und empfindlichkeit
CN111610334A (zh) * 2020-05-18 2020-09-01 山东省肿瘤防治研究院（山东省肿瘤医院） 一种基于细胞大小过滤识别肿瘤患者外周血循环肿瘤细胞的方法
CN118340775A (zh) * 2023-01-09 2024-07-16 维眸生物科技(浙江)有限公司 一种含vvn539的眼用组合物及其用途
WO2025175150A1 (en) * 2024-02-16 2025-08-21 Allergan, Inc. Enhanced artificial tear formulations

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EP2637684A4 (de) 2010-11-08 2014-05-07 Healor Ltd Gepufferte ophthalmische zusammensetzungen und verwendungsverfahren dafür

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Publication number Priority date Publication date Assignee Title
WO2008048675A2 (en) * 2006-10-20 2008-04-24 Celldex Therapeutics, Inc. Treatment for age-related macular degeneration and other diseases of the eye

Also Published As

Publication number Publication date
WO2012063237A3 (en) 2012-11-22
RU2013117209A (ru) 2014-10-27
JP2013543862A (ja) 2013-12-09
CA2812164A1 (en) 2012-05-18
EP2944319A1 (de) 2015-11-18
WO2012063237A2 (en) 2012-05-18
CN103249429A (zh) 2013-08-14
US20120264681A1 (en) 2012-10-18
CN104758921A (zh) 2015-07-08
EP2637684A2 (de) 2013-09-18
US20150094260A1 (en) 2015-04-02
AU2011327785A1 (en) 2013-03-07

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