EP2532426A3 - Cartridge, centrifuge and method - Google Patents

Cartridge, centrifuge and method Download PDF

Info

Publication number
EP2532426A3
EP2532426A3 EP20120163519 EP12163519A EP2532426A3 EP 2532426 A3 EP2532426 A3 EP 2532426A3 EP 20120163519 EP20120163519 EP 20120163519 EP 12163519 A EP12163519 A EP 12163519A EP 2532426 A3 EP2532426 A3 EP 2532426A3
Authority
EP
European Patent Office
Prior art keywords
chamber
drum
centrifuge
cartridge
central axis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP20120163519
Other languages
German (de)
French (fr)
Other versions
EP2532426A2 (en
EP2532426B1 (en
Inventor
Martina Daub
Juergen Steigert
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Robert Bosch GmbH
Original Assignee
Robert Bosch GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Robert Bosch GmbH filed Critical Robert Bosch GmbH
Publication of EP2532426A2 publication Critical patent/EP2532426A2/en
Publication of EP2532426A3 publication Critical patent/EP2532426A3/en
Application granted granted Critical
Publication of EP2532426B1 publication Critical patent/EP2532426B1/en
Not-in-force legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5021—Test tubes specially adapted for centrifugation purposes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F29/00—Mixers with rotating receptacles
    • B01F29/15—Use of centrifuges for mixing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F29/00—Mixers with rotating receptacles
    • B01F29/30—Mixing the contents of individual packages or containers, e.g. by rotating tins or bottles
    • B01F29/32—Containers specially adapted for coupling to rotating frames or the like; Coupling means therefor
    • B01F29/321—Containers specially adapted for coupling to rotating frames or the like; Coupling means therefor of test-tubes or the like
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F31/00—Mixers with shaking, oscillating, or vibrating mechanisms
    • B01F31/42—Mixers with shaking, oscillating, or vibrating mechanisms with pendulum stirrers, i.e. with stirrers suspended so as to oscillate about fixed points or axes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/45—Magnetic mixers; Mixers with magnetically driven stirrers
    • B01F33/453—Magnetic mixers; Mixers with magnetically driven stirrers using supported or suspended stirring elements
    • B01F33/4533—Magnetic mixers; Mixers with magnetically driven stirrers using supported or suspended stirring elements supporting the stirring element in one point
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/71—Feed mechanisms
    • B01F35/713—Feed mechanisms comprising breaking packages or parts thereof, e.g. piercing or opening sealing elements between compartments or cartridges
    • B01F35/7137—Piercing, perforating or melting membranes or closures which seal the compartments
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/71—Feed mechanisms
    • B01F35/716—Feed mechanisms characterised by the relative arrangement of the containers for feeding or mixing the components
    • B01F35/7161—Feed mechanisms characterised by the relative arrangement of the containers for feeding or mixing the components the containers being connected coaxially before contacting the contents
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/71—Feed mechanisms
    • B01F35/717—Feed mechanisms characterised by the means for feeding the components to the mixer
    • B01F35/71725—Feed mechanisms characterised by the means for feeding the components to the mixer using centrifugal forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/16—Reagents, handling or storing thereof
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0672—Integrated piercing tool
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0832—Geometry, shape and general structure cylindrical, tube shaped
    • B01L2300/0841—Drums
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0409—Moving fluids with specific forces or mechanical means specific forces centrifugal forces

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Centrifugal Separators (AREA)
  • Mixers With Rotating Receptacles And Mixers With Vibration Mechanisms (AREA)

Abstract

Die vorliegende Erfindung schafft eine Kartusche (100) zum Einsetzen in eine Zentrifuge (1200) und Zentrifugieren derselben, aufweisend eine erste Trommel (108), welche eine erste Kammer (124) aufweist, und eine Verstelleinrichtung (300), welche dazu eingerichtet ist, die erste Trommel (108) um deren Mittelachse (104) zu drehen, um dadurch die erste Kammer (124) wahlweise mit einer zweiten oder einer dritten Kammer (120, 122, 132, 136) leitend zu verbinden, oder eine erste Trommel (108), welche eine erste und eine zweite Kammer (124, 126) aufweist, und eine Verstelleinrichtung (300), welche dazu eingerichtet ist, die erste Trommel (108) um deren Mittelachse (104) zu drehen, um dadurch wahlweise die erste Kammer (124) mit einer dritten Kammer (120) oder die zweite Kammer (122) mit der dritten Kammer (120) leitend zu verbinden, wobei die Verstelleinrichtung (300) einen Aktor (139) aufweist, welcher die erste Trommel (108) um die Mittelachse (104) direkt oder indirekt bewegt.

Figure imgaf001
The present invention provides a cartridge (100) for insertion into a centrifuge (1200) and centrifuging thereof, comprising a first drum (108) having a first chamber (124) and an adjustment device (300) adapted to rotating the first drum (108) about its central axis (104) to thereby conductively connect the first chamber (124) to a second or a third chamber (120, 122, 132, 136) or a first drum (108 ) having a first and a second chamber (124, 126), and an adjusting device (300) which is adapted to rotate the first drum (108) about its central axis (104), thereby selectively the first chamber ( 124) with a third chamber (120) or the second chamber (122) with the third chamber (120) to conductively connect, wherein the adjusting device (300) comprises an actuator (139) which surrounds the first drum (108) about the central axis (104) moved directly or indirectly.
Figure imgaf001
EP12163519.7A 2011-06-07 2012-04-10 Cartridge for insertion into a centrifuge, centrifuge and method Not-in-force EP2532426B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE102011077124A DE102011077124A1 (en) 2011-06-07 2011-06-07 Cartridge, centrifuge and process

Publications (3)

Publication Number Publication Date
EP2532426A2 EP2532426A2 (en) 2012-12-12
EP2532426A3 true EP2532426A3 (en) 2013-03-27
EP2532426B1 EP2532426B1 (en) 2015-11-18

Family

ID=46027604

Family Applications (1)

Application Number Title Priority Date Filing Date
EP12163519.7A Not-in-force EP2532426B1 (en) 2011-06-07 2012-04-10 Cartridge for insertion into a centrifuge, centrifuge and method

Country Status (4)

Country Link
US (1) US9272278B2 (en)
EP (1) EP2532426B1 (en)
CN (1) CN102814242A (en)
DE (1) DE102011077124A1 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102011077134A1 (en) 2011-06-07 2012-12-13 Robert Bosch Gmbh Cartridge, centrifuge and method for mixing a first and second component
DE102011077115A1 (en) * 2011-06-07 2012-12-13 Robert Bosch Gmbh Cartridge, centrifuge and process
DE102013200352A1 (en) * 2013-01-14 2014-07-17 Robert Bosch Gmbh Cartridge, centrifuge for this cartridge and procedures
US9308508B2 (en) * 2013-07-22 2016-04-12 Kianoosh Peyvan Sequential delivery device and method
US10112199B2 (en) 2014-12-03 2018-10-30 Fiberlite Centrifuge, Llc Centrifuge sample container and closure therefore
US9987634B2 (en) 2014-12-03 2018-06-05 Fiberlite Centrifuge, Llc Centrifuge sample container and closure therefor
USD777941S1 (en) * 2015-07-17 2017-01-31 Fiberlite Centrifuge, Llc Centrifuge bottle
DE102017115191A1 (en) * 2017-07-06 2019-01-10 A. u. K. Müller GmbH & Co. KG Valve, in particular servo valve
KR102028953B1 (en) * 2019-02-01 2019-10-07 비아로지스 주식회사 Biological Material Manufacturing Device and Driving Method Thereof

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102006003532A1 (en) * 2006-01-24 2007-07-26 INSTITUT FüR MIKROTECHNIK MAINZ GMBH Centrifugal separation of microlitre liquid quantities of biochemical or medical samples uses rotor and stator chip modules in a 'lab on chip' arrangement
US20090023610A1 (en) * 2004-03-26 2009-01-22 Regis Peytavi Removable microfluidic cell
EP2514515A1 (en) * 2011-04-20 2012-10-24 Robert Bosch GmbH Mixing chamber, cartridge and related method for mixing a first and a second component
EP2532427A2 (en) * 2011-06-07 2012-12-12 Robert Bosch Gmbh Cartridge, centrifuge and method
EP2532428A2 (en) * 2011-06-07 2012-12-12 Robert Bosch Gmbh Cartridge, centrifuge and method for mixing a first and a second component
EP2535108A1 (en) * 2011-06-07 2012-12-19 Robert Bosch Gmbh Microfluidic System and method of operating the system

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4806019A (en) * 1985-09-03 1989-02-21 Nova Scotia Research Foundation Corporation Method and apparatus for mixing two or more components such as immiscible liquids
FR2665378B1 (en) * 1990-08-03 1992-10-09 Guigan Jean DEVICE FOR SEPARATING BY CENTRIFUGATION TWO PHASES FROM A SAMPLE OF A HETEROGENEOUS LIQUID, USABLE IN PARTICULAR FOR THE SEPARATION OF TOTAL BLOOD PLASMA.
CA2206516C (en) * 1994-12-02 2007-04-17 Bristol-Myers Squibb Company Centrifuge reagent delivery system
US5733446A (en) * 1994-12-02 1998-03-31 Bristol-Myers Squibb Company Centrifuge with annular filter
US5707331A (en) * 1995-05-05 1998-01-13 John R. Wells Automatic multiple-decanting centrifuge
DE102004023427A1 (en) 2004-05-09 2005-12-22 Microfluidic Chipshop Gmbh Connector-distributor for chip systems, used e.g. in transport or analysis of fluids, includes luer connector and penetrations for multiple fluid channels in chip component
JP2008224383A (en) 2007-03-12 2008-09-25 Olympus Corp Reagent storage and autoanalyzer
US9075030B2 (en) 2008-05-22 2015-07-07 Hitachi High-Technologies Corporation Automatic analyzer
EP2532458B1 (en) 2011-06-06 2017-03-29 HILTI Aktiengesellschaft Threaded bar deburrer

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090023610A1 (en) * 2004-03-26 2009-01-22 Regis Peytavi Removable microfluidic cell
DE102006003532A1 (en) * 2006-01-24 2007-07-26 INSTITUT FüR MIKROTECHNIK MAINZ GMBH Centrifugal separation of microlitre liquid quantities of biochemical or medical samples uses rotor and stator chip modules in a 'lab on chip' arrangement
EP2514515A1 (en) * 2011-04-20 2012-10-24 Robert Bosch GmbH Mixing chamber, cartridge and related method for mixing a first and a second component
EP2532427A2 (en) * 2011-06-07 2012-12-12 Robert Bosch Gmbh Cartridge, centrifuge and method
EP2532428A2 (en) * 2011-06-07 2012-12-12 Robert Bosch Gmbh Cartridge, centrifuge and method for mixing a first and a second component
EP2535108A1 (en) * 2011-06-07 2012-12-19 Robert Bosch Gmbh Microfluidic System and method of operating the system

Also Published As

Publication number Publication date
EP2532426A2 (en) 2012-12-12
US9272278B2 (en) 2016-03-01
US20120316050A1 (en) 2012-12-13
DE102011077124A1 (en) 2012-12-13
CN102814242A (en) 2012-12-12
EP2532426B1 (en) 2015-11-18

Similar Documents

Publication Publication Date Title
EP2532426A3 (en) Cartridge, centrifuge and method
EP2532427A3 (en) Cartridge, centrifuge and method
EP2532428A3 (en) Cartridge, centrifuge and method for mixing a first and a second component
DE102015121004B4 (en) Gear holding device and method for holding a gear
EP2642326A3 (en) Automatic calibration of a microscope scanning system
EP2060346A3 (en) Densification tool, press comprising such tool and process for the densification of a sintered part or powder
EP1863093A3 (en) Organic light-emitting component, device with an organic light-emitting component and illumination device and method for manufacturing an organic light-emitting component
DE102014119470A1 (en) Structured surface with gradual switchable adhesion
EP2693079A3 (en) Planetary gear mechanism and a handling device equipped with such a planetary gear
EP2262018A3 (en) Thermoelectric device and method for producing same
EP2371462A3 (en) Hand-held cleaning device for cleaning conduits
EP2546124A3 (en) Sub-assembly and method for connecting components with different thermal expansion coefficients
EP2354768A3 (en) Device for reading consumer values and communication method
EP2503795A3 (en) Hearing aid with feedback suppression device and method for operating a hearing aid
EP3415270A3 (en) Processing machine for the production of dental workpieces
EP3261223A3 (en) Electrical machine and method for manufacturing an electrical machine
EP3064076A3 (en) Method and apparatus for inserting oriented objects into a filter rod
EP2730338A3 (en) Device for shredding a substrate and housing wall for such a device
EP2565463A3 (en) Vacuum pump
EP2953216A3 (en) Spark gap with a cooling and/or damping device
EP2787284A3 (en) Device for a domestic appliance with a variable position first rail of an extraction device and domestic appliance with such a device and method for operating a device
EP2727692A3 (en) Method for producing a sinter composite component and sinter composite component
EP2270947A3 (en) Method and device for energy distribution
EP2071183A3 (en) Clockwork motor
EP3296750A3 (en) Device and method for measuring a rotational movement of a rotatable component, in particular a direction of rotation

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

AK Designated contracting states

Kind code of ref document: A2

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

AX Request for extension of the european patent

Extension state: BA ME

PUAL Search report despatched

Free format text: ORIGINAL CODE: 0009013

AK Designated contracting states

Kind code of ref document: A3

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

AX Request for extension of the european patent

Extension state: BA ME

RIC1 Information provided on ipc code assigned before grant

Ipc: B01F 9/00 20060101ALI20130218BHEP

Ipc: B01L 3/14 20060101AFI20130218BHEP

17P Request for examination filed

Effective date: 20130927

RBV Designated contracting states (corrected)

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

17Q First examination report despatched

Effective date: 20140320

REG Reference to a national code

Ref country code: DE

Ref legal event code: R079

Ref document number: 502012005228

Country of ref document: DE

Free format text: PREVIOUS MAIN CLASS: B01L0003140000

Ipc: B01F0009000000

GRAP Despatch of communication of intention to grant a patent

Free format text: ORIGINAL CODE: EPIDOSNIGR1

INTG Intention to grant announced

Effective date: 20150520

RIC1 Information provided on ipc code assigned before grant

Ipc: B01F 13/08 20060101ALI20150508BHEP

Ipc: B01L 3/00 20060101ALI20150508BHEP

Ipc: B01F 11/04 20060101ALI20150508BHEP

Ipc: B01F 15/02 20060101ALI20150508BHEP

Ipc: B01F 9/00 20060101AFI20150508BHEP

GRAS Grant fee paid

Free format text: ORIGINAL CODE: EPIDOSNIGR3

GRAA (expected) grant

Free format text: ORIGINAL CODE: 0009210

AK Designated contracting states

Kind code of ref document: B1

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

REG Reference to a national code

Ref country code: GB

Ref legal event code: FG4D

Free format text: NOT ENGLISH

REG Reference to a national code

Ref country code: CH

Ref legal event code: EP

REG Reference to a national code

Ref country code: AT

Ref legal event code: REF

Ref document number: 761231

Country of ref document: AT

Kind code of ref document: T

Effective date: 20151215

REG Reference to a national code

Ref country code: IE

Ref legal event code: FG4D

Free format text: LANGUAGE OF EP DOCUMENT: GERMAN

REG Reference to a national code

Ref country code: DE

Ref legal event code: R096

Ref document number: 502012005228

Country of ref document: DE

REG Reference to a national code

Ref country code: LT

Ref legal event code: MG4D

REG Reference to a national code

Ref country code: NL

Ref legal event code: FP

REG Reference to a national code

Ref country code: FR

Ref legal event code: PLFP

Year of fee payment: 5

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: ES

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20151118

Ref country code: NO

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20160218

Ref country code: LT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20151118

Ref country code: IS

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20160318

Ref country code: HR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20151118

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: LV

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20151118

Ref country code: RS

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20151118

Ref country code: PT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20160318

Ref country code: PL

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20151118

Ref country code: SE

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20151118

Ref country code: FI

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20151118

Ref country code: GR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20160219

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: CZ

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20151118

REG Reference to a national code

Ref country code: DE

Ref legal event code: R097

Ref document number: 502012005228

Country of ref document: DE

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: DK

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20151118

Ref country code: EE

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20151118

Ref country code: BE

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20160430

Ref country code: SK

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20151118

Ref country code: SM

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20151118

Ref country code: RO

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20151118

PLBE No opposition filed within time limit

Free format text: ORIGINAL CODE: 0009261

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: NO OPPOSITION FILED WITHIN TIME LIMIT

26N No opposition filed

Effective date: 20160819

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: SI

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20151118

REG Reference to a national code

Ref country code: CH

Ref legal event code: PL

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: LU

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20160410

REG Reference to a national code

Ref country code: IE

Ref legal event code: MM4A

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: CH

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20160430

Ref country code: LI

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20160430

REG Reference to a national code

Ref country code: FR

Ref legal event code: PLFP

Year of fee payment: 6

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: IE

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20160410

REG Reference to a national code

Ref country code: FR

Ref legal event code: PLFP

Year of fee payment: 7

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: CY

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20151118

Ref country code: HU

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT; INVALID AB INITIO

Effective date: 20120410

REG Reference to a national code

Ref country code: AT

Ref legal event code: MM01

Ref document number: 761231

Country of ref document: AT

Kind code of ref document: T

Effective date: 20170410

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: MK

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20151118

Ref country code: TR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20151118

Ref country code: MC

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20151118

Ref country code: MT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20151118

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: BG

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20151118

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: AT

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20170410

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: AL

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20151118

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: NL

Payment date: 20190418

Year of fee payment: 8

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: IT

Payment date: 20190419

Year of fee payment: 8

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: FR

Payment date: 20200421

Year of fee payment: 9

Ref country code: DE

Payment date: 20200623

Year of fee payment: 9

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: GB

Payment date: 20200423

Year of fee payment: 9

REG Reference to a national code

Ref country code: NL

Ref legal event code: MM

Effective date: 20200501

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: NL

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20200501

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: IT

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20200410

REG Reference to a national code

Ref country code: DE

Ref legal event code: R119

Ref document number: 502012005228

Country of ref document: DE

REG Reference to a national code

Ref country code: DE

Ref legal event code: R079

Ref document number: 502012005228

Country of ref document: DE

Free format text: PREVIOUS MAIN CLASS: B01F0009000000

Ipc: B01F0029000000

GBPC Gb: european patent ceased through non-payment of renewal fee

Effective date: 20210410

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: DE

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20211103

Ref country code: GB

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20210410

Ref country code: FR

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20210430