EP2532428A3 - Cartridge, centrifuge and method for mixing a first and a second component - Google Patents
Cartridge, centrifuge and method for mixing a first and a second component Download PDFInfo
- Publication number
- EP2532428A3 EP2532428A3 EP12163532A EP12163532A EP2532428A3 EP 2532428 A3 EP2532428 A3 EP 2532428A3 EP 12163532 A EP12163532 A EP 12163532A EP 12163532 A EP12163532 A EP 12163532A EP 2532428 A3 EP2532428 A3 EP 2532428A3
- Authority
- EP
- European Patent Office
- Prior art keywords
- mixing
- centrifuge
- cartridge
- component
- electromagnetic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5021—Test tubes specially adapted for centrifugation purposes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F29/00—Mixers with rotating receptacles
- B01F29/15—Use of centrifuges for mixing
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F29/00—Mixers with rotating receptacles
- B01F29/30—Mixing the contents of individual packages or containers, e.g. by rotating tins or bottles
- B01F29/32—Containers specially adapted for coupling to rotating frames or the like; Coupling means therefor
- B01F29/321—Containers specially adapted for coupling to rotating frames or the like; Coupling means therefor of test-tubes or the like
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F31/00—Mixers with shaking, oscillating, or vibrating mechanisms
- B01F31/42—Mixers with shaking, oscillating, or vibrating mechanisms with pendulum stirrers, i.e. with stirrers suspended so as to oscillate about fixed points or axes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F33/00—Other mixers; Mixing plants; Combinations of mixers
- B01F33/45—Magnetic mixers; Mixers with magnetically driven stirrers
- B01F33/453—Magnetic mixers; Mixers with magnetically driven stirrers using supported or suspended stirring elements
- B01F33/4533—Magnetic mixers; Mixers with magnetically driven stirrers using supported or suspended stirring elements supporting the stirring element in one point
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/71—Feed mechanisms
- B01F35/713—Feed mechanisms comprising breaking packages or parts thereof, e.g. piercing or opening sealing elements between compartments or cartridges
- B01F35/7137—Piercing, perforating or melting membranes or closures which seal the compartments
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/71—Feed mechanisms
- B01F35/716—Feed mechanisms characterised by the relative arrangement of the containers for feeding or mixing the components
- B01F35/7161—Feed mechanisms characterised by the relative arrangement of the containers for feeding or mixing the components the containers being connected coaxially before contacting the contents
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/71—Feed mechanisms
- B01F35/717—Feed mechanisms characterised by the means for feeding the components to the mixer
- B01F35/71725—Feed mechanisms characterised by the means for feeding the components to the mixer using centrifugal forces
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/16—Reagents, handling or storing thereof
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0672—Integrated piercing tool
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0832—Geometry, shape and general structure cylindrical, tube shaped
- B01L2300/0841—Drums
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0409—Moving fluids with specific forces or mechanical means specific forces centrifugal forces
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/043—Moving fluids with specific forces or mechanical means specific forces magnetic forces
Landscapes
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Clinical Laboratory Science (AREA)
- Mixers With Rotating Receptacles And Mixers With Vibration Mechanisms (AREA)
- Centrifugal Separators (AREA)
- Dental Tools And Instruments Or Auxiliary Dental Instruments (AREA)
Abstract
Die vorliegende Erfindung schafft eine Kartusche (100) zum Einsetzen in eine Zentrifuge (600) und Zentrifugieren derselben, aufweisend eine Mischkammer (124), welche einen Behälter (500) für zumindest eine erste und zweite Komponente (502, 504) und elektromagnetische Partikel (506) umfasst, wobei die elektromagnetischen Partikel (506) mittels einer Elektromagnetkraft (510) für ein Mischen der ersten und zweiten Komponente (502, 504) bewegbar sind. The present invention provides a cartridge (100) for insertion into a centrifuge (600) and centrifuging the same, comprising a mixing chamber (124) comprising a container (500) for at least a first and second component (502, 504) and electromagnetic particles (50). 506), wherein the electromagnetic particles (506) are movable by means of an electromagnetic force (510) for mixing the first and second components (502, 504).
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102011077134A DE102011077134A1 (en) | 2011-06-07 | 2011-06-07 | Cartridge, centrifuge and method for mixing a first and second component |
Publications (3)
Publication Number | Publication Date |
---|---|
EP2532428A2 EP2532428A2 (en) | 2012-12-12 |
EP2532428A3 true EP2532428A3 (en) | 2013-04-03 |
EP2532428B1 EP2532428B1 (en) | 2014-07-02 |
Family
ID=46027608
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP12163532.0A Not-in-force EP2532428B1 (en) | 2011-06-07 | 2012-04-10 | Cartridge, centrifuge and method for mixing a first and a second component |
Country Status (4)
Country | Link |
---|---|
US (1) | US9475043B2 (en) |
EP (1) | EP2532428B1 (en) |
CN (1) | CN102814240B (en) |
DE (1) | DE102011077134A1 (en) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102011077115A1 (en) | 2011-06-07 | 2012-12-13 | Robert Bosch Gmbh | Cartridge, centrifuge and process |
DE102011077124A1 (en) * | 2011-06-07 | 2012-12-13 | Robert Bosch Gmbh | Cartridge, centrifuge and process |
WO2014058868A1 (en) * | 2012-10-10 | 2014-04-17 | California Institute Of Technology | Devices and methods for cell lysis and sample preparation through centrifugation |
US20140135198A1 (en) * | 2012-11-12 | 2014-05-15 | California Institute Of Technology | Devices and methods for nucleic acid extraction capture and concentration using electric fields and centrifugation |
DE102013201505A1 (en) * | 2013-01-30 | 2014-07-31 | Robert Bosch Gmbh | Apparatus for extracting dry body fluid in a sample, cartridge and method |
DE102013203684A1 (en) * | 2013-03-05 | 2014-09-25 | Robert Bosch Gmbh | Method and device for fluidically coupling cavities in a centrifuge |
WO2014163593A1 (en) * | 2013-04-03 | 2014-10-09 | Sanko Ozel Egitim Hizmetleri A.S. | A machine enabling separation of the blood by magnetism and autonomous radioactive substance marking of the white blood cells |
DE102013220064B3 (en) * | 2013-10-02 | 2014-12-24 | Hahn-Schickard-Gesellschaft für angewandte Forschung e.V. | DEVICE AND METHOD FOR MOVING A SOLID PHASE IN A MULTIPLE OF CHAMBERS |
DE102013222283B3 (en) | 2013-11-04 | 2015-01-15 | Robert Bosch Gmbh | Apparatus and method for handling reagents |
KR101472821B1 (en) * | 2014-05-14 | 2014-12-16 | 김준우 | Component separator |
CA3100506A1 (en) * | 2018-09-21 | 2020-03-26 | Foss Analytical A/S | A sampling device, a system comprising the sampling device and a method |
Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20090023610A1 (en) * | 2004-03-26 | 2009-01-22 | Regis Peytavi | Removable microfluidic cell |
US20090269854A1 (en) * | 2005-12-05 | 2009-10-29 | Rohm Co., Ltd. | Microchip |
EP2329877A1 (en) * | 2009-12-04 | 2011-06-08 | Roche Diagnostics GmbH | Microfluidic element for analysing a fluid sample |
EP2388067A1 (en) * | 2010-05-17 | 2011-11-23 | Roche Diagnostics GmbH | Method and device for mixing a liquid by a microfluidic test element, and test element |
EP2514515A1 (en) * | 2011-04-20 | 2012-10-24 | Robert Bosch GmbH | Mixing chamber, cartridge and related method for mixing a first and a second component |
EP2532426A2 (en) * | 2011-06-07 | 2012-12-12 | Robert Bosch Gmbh | Cartridge, centrifuge and method |
EP2532427A2 (en) * | 2011-06-07 | 2012-12-12 | Robert Bosch Gmbh | Cartridge, centrifuge and method |
EP2535108A1 (en) * | 2011-06-07 | 2012-12-19 | Robert Bosch Gmbh | Microfluidic System and method of operating the system |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2184152A (en) * | 1939-10-27 | 1939-12-19 | Jacob A Saffir | Ampoule |
US2854143A (en) * | 1957-02-13 | 1958-09-30 | Ohio Commw Eng Co | Centrifugal stratifier with plural filter means |
US3300051A (en) * | 1963-09-26 | 1967-01-24 | Internat Equipment Co | Filter tube for use in a centrifuge |
US3356346A (en) * | 1966-01-03 | 1967-12-05 | Landsberger Kurt | Test tube stirring support |
US3583627A (en) * | 1969-09-04 | 1971-06-08 | Onslow H Wilson | Apparatus for the concentration of macromolecules and subcellular particles from dilute solutions |
US5073341A (en) * | 1985-08-21 | 1991-12-17 | Biotope, Inc. | Devices for conducting specific binding assays |
US5186827A (en) * | 1991-03-25 | 1993-02-16 | Immunicon Corporation | Apparatus for magnetic separation featuring external magnetic means |
US5466574A (en) * | 1991-03-25 | 1995-11-14 | Immunivest Corporation | Apparatus and methods for magnetic separation featuring external magnetic means |
US5552064A (en) * | 1993-02-26 | 1996-09-03 | Ortho Diagnostic Systems, Inc. | Column agglutination assay and device using biphasic centrifugation |
US5601711A (en) * | 1994-10-31 | 1997-02-11 | Gelman Sciences Inc. | Selective separation filter device |
US6150182A (en) | 1998-11-30 | 2000-11-21 | Cassaday; Michael M. | Method for separation of components in a biochemical reaction utilizing a combination of magnetic and centrifugal processes |
US6537503B1 (en) * | 1999-12-03 | 2003-03-25 | Becton Dickinson And Company | Device and method for separating components of a fluid sample |
CN1247309C (en) * | 2001-07-26 | 2006-03-29 | 张竞 | Centrifugal separation machine |
US6939032B2 (en) * | 2001-10-25 | 2005-09-06 | Erie Scientific Company | Cover slip mixing apparatus |
SE0300009D0 (en) * | 2003-01-03 | 2003-01-03 | Bomill Ab | Sorting Device |
FI20040159A0 (en) * | 2003-10-20 | 2004-02-02 | Bio Mobile Oy | Magnetic transfer method, microparticle transfer device, and reaction unit |
JP4732913B2 (en) | 2006-02-09 | 2011-07-27 | ローム株式会社 | Microchip and method of using microchip |
US20110097816A1 (en) * | 2009-10-23 | 2011-04-28 | Goodwin Paul C | Methods for changing densities of non-target particles of a suspension |
CN201524452U (en) * | 2009-11-06 | 2010-07-14 | 重庆工商大学 | Self-absorption centrifugal separation demulsification processing machine for emulsified oil |
-
2011
- 2011-06-07 DE DE102011077134A patent/DE102011077134A1/en not_active Withdrawn
-
2012
- 2012-04-10 EP EP12163532.0A patent/EP2532428B1/en not_active Not-in-force
- 2012-06-06 CN CN201210184002.1A patent/CN102814240B/en not_active Expired - Fee Related
- 2012-06-07 US US13/490,882 patent/US9475043B2/en not_active Expired - Fee Related
Patent Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20090023610A1 (en) * | 2004-03-26 | 2009-01-22 | Regis Peytavi | Removable microfluidic cell |
US20090269854A1 (en) * | 2005-12-05 | 2009-10-29 | Rohm Co., Ltd. | Microchip |
EP2329877A1 (en) * | 2009-12-04 | 2011-06-08 | Roche Diagnostics GmbH | Microfluidic element for analysing a fluid sample |
EP2388067A1 (en) * | 2010-05-17 | 2011-11-23 | Roche Diagnostics GmbH | Method and device for mixing a liquid by a microfluidic test element, and test element |
EP2514515A1 (en) * | 2011-04-20 | 2012-10-24 | Robert Bosch GmbH | Mixing chamber, cartridge and related method for mixing a first and a second component |
EP2532426A2 (en) * | 2011-06-07 | 2012-12-12 | Robert Bosch Gmbh | Cartridge, centrifuge and method |
EP2532427A2 (en) * | 2011-06-07 | 2012-12-12 | Robert Bosch Gmbh | Cartridge, centrifuge and method |
EP2535108A1 (en) * | 2011-06-07 | 2012-12-19 | Robert Bosch Gmbh | Microfluidic System and method of operating the system |
Non-Patent Citations (1)
Title |
---|
GRUMANN, MARKUS: "Readout of Diagnostic Assays on a Centrifugal Microfluidic Platform", 30 October 2005, DISSERTATION UNI FREIBURG IM BREISGAU, http://ebookbrowse.com/051228-grumann-phd-thesis-pdf-d45217302, XP002691220 * |
Also Published As
Publication number | Publication date |
---|---|
US20120314531A1 (en) | 2012-12-13 |
US9475043B2 (en) | 2016-10-25 |
CN102814240A (en) | 2012-12-12 |
EP2532428A2 (en) | 2012-12-12 |
EP2532428B1 (en) | 2014-07-02 |
CN102814240B (en) | 2016-12-14 |
DE102011077134A1 (en) | 2012-12-13 |
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