EP2361386A1 - Unité de fiche et système de connexion pour connecter des capillaires, en particulier pour chromatographie en phase liquide à haute performance - Google Patents

Unité de fiche et système de connexion pour connecter des capillaires, en particulier pour chromatographie en phase liquide à haute performance

Info

Publication number
EP2361386A1
EP2361386A1 EP09807486A EP09807486A EP2361386A1 EP 2361386 A1 EP2361386 A1 EP 2361386A1 EP 09807486 A EP09807486 A EP 09807486A EP 09807486 A EP09807486 A EP 09807486A EP 2361386 A1 EP2361386 A1 EP 2361386A1
Authority
EP
European Patent Office
Prior art keywords
plug
capillary
unit
sealing element
socket
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP09807486A
Other languages
German (de)
English (en)
Inventor
Hermann Hochgraeber
Adolf Satzinger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dionex Softron GmbH
Original Assignee
Dionex Softron GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dionex Softron GmbH filed Critical Dionex Softron GmbH
Publication of EP2361386A1 publication Critical patent/EP2361386A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16L—PIPES; JOINTS OR FITTINGS FOR PIPES; SUPPORTS FOR PIPES, CABLES OR PROTECTIVE TUBING; MEANS FOR THERMAL INSULATION IN GENERAL
    • F16L21/00—Joints with sleeve or socket
    • F16L21/02—Joints with sleeve or socket with elastic sealing rings between pipe and sleeve or between pipe and socket, e.g. with rolling or other prefabricated profiled rings
    • F16L21/04—Joints with sleeve or socket with elastic sealing rings between pipe and sleeve or between pipe and socket, e.g. with rolling or other prefabricated profiled rings in which sealing rings are compressed by axially-movable members
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16L—PIPES; JOINTS OR FITTINGS FOR PIPES; SUPPORTS FOR PIPES, CABLES OR PROTECTIVE TUBING; MEANS FOR THERMAL INSULATION IN GENERAL
    • F16L19/00—Joints in which sealing surfaces are pressed together by means of a member, e.g. a swivel nut, screwed on or into one of the joint parts
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16L—PIPES; JOINTS OR FITTINGS FOR PIPES; SUPPORTS FOR PIPES, CABLES OR PROTECTIVE TUBING; MEANS FOR THERMAL INSULATION IN GENERAL
    • F16L19/00—Joints in which sealing surfaces are pressed together by means of a member, e.g. a swivel nut, screwed on or into one of the joint parts
    • F16L19/06—Joints in which sealing surfaces are pressed together by means of a member, e.g. a swivel nut, screwed on or into one of the joint parts in which radial clamping is obtained by wedging action on non-deformed pipe ends
    • F16L19/061—Joints in which sealing surfaces are pressed together by means of a member, e.g. a swivel nut, screwed on or into one of the joint parts in which radial clamping is obtained by wedging action on non-deformed pipe ends a pressure ring being arranged between the clamping ring and the threaded member or the connecting member
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16L—PIPES; JOINTS OR FITTINGS FOR PIPES; SUPPORTS FOR PIPES, CABLES OR PROTECTIVE TUBING; MEANS FOR THERMAL INSULATION IN GENERAL
    • F16L21/00—Joints with sleeve or socket
    • F16L21/02—Joints with sleeve or socket with elastic sealing rings between pipe and sleeve or between pipe and socket, e.g. with rolling or other prefabricated profiled rings
    • F16L21/035—Joints with sleeve or socket with elastic sealing rings between pipe and sleeve or between pipe and socket, e.g. with rolling or other prefabricated profiled rings placed around the spigot end before connection
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G01N30/6004—Construction of the column end pieces
    • G01N30/6026—Fluid seals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G01N30/6034—Construction of the column joining multiple columns
    • G01N30/6039—Construction of the column joining multiple columns in series
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G01N30/6091—Cartridges

Definitions

  • the invention relates to a connector unit for connecting capillaries, in particular for high performance liquid chromatography, with the features of the preamble of claim 1. Furthermore, the invention relates to a connection system consisting of a socket unit and such a plug unit according to claim 11.
  • connecting lines In chromatographic plants, liquids or gases are conveyed through suitable connecting lines between the components of the plant concerned.
  • These connecting lines which may be made of stainless steel for example, have at their ends via suitable connection systems, also referred to as fittings, in order to establish a tight connection with the connections of the components can.
  • connection system was already described in 1975 in US 3,880,452.
  • the connecting line between two components forming capillary is thereby inserted into the capillary receiving opening of a socket unit or connection unit and fixed by means of a fastening screw which has a central bore for guiding the capillary in the socket.
  • a fastening screw which has a central bore for guiding the capillary in the socket.
  • one or more sealing elements which surround the capillary in its front end region are pressed in by means of the fastening screw when connecting the capillary and the socket unit into the capillary receiving opening, which runs conically inwards.
  • sealing point does not take place in the plane perpendicular to the longitudinal axis of the capillary plane of the end face, but in the axial direction a certain distance from the end face is offset backwards. This results in a dead volume, which has a disadvantageous effect especially in high performance liquid chromatography.
  • sealing elements are frequently used, as described, for example, in the prior art (FIG. 2) in US Pat. No. 4,619,473. These are annular sealing elements, which are usually also made of stainless steel and have a conical shape of the outer diameter in longitudinal section.
  • Such a sealing element acts with a conical Receiving opening in the socket unit together, wherein the conical receiving opening with respect to the longitudinal axis of the capillary has a larger angle than the sealing element.
  • the capillary is even deformed by the pressure of the fastening screw, possibly damaged, and a tight connection may not be possible. Because the positively and non-positively fastened on the capillary sealing element can not move in the axial direction.
  • US Pat. No. 6,494,500 describes a self-adjusting plug for high-performance liquid chromatography in which the capillary is connected via a screw provided in the fastening screw. spring is biased axially in the direction of the capillary receiving openings of the socket unit.
  • a replaceable ferrule is used, which, however, e- b consider again conical in its front region and the seal with a more conical inner wall of the Ferrulentextö réelle cooperates.
  • the sealing element consists of a metal, for example stainless steel.
  • a unit for connecting capillaries for gas chromatography is known from US Pat. No. 4,083,704, in which the capillaries are also connected with their end faces in abutment.
  • the fixation of the capillaries is effected by means of wedge-shaped ring elements in longitudinal section, which cooperate with correspondingly conical recesses in the connecting housing.
  • the sealing is simpler than a compound suitable for high-performance liquid chromatography, since in gas chromatography the pressures used are significantly lower, for example up to 6 bar.
  • the known connection systems have the disadvantage that there is the danger that the sealing element gets stuck in the relevant receiving opening of the socket unit when dismantling the plug unit and pulling out the capillary from the socket unit.
  • the present invention seeks to provide a plug unit for the connection of capillaries, especially for the Hoch elegants weakness- keitschromatographie, which can be used in a simple way for capillaries with different outer diameter in conjunction with socket units with conventional diameters of receiving openings is.
  • the sealing element separates from the capillary during disassembly of the plug unit and remains in the socket unit.
  • the invention is based on creating a connection system with such a plug unit.
  • the invention is based on the recognition that a concern of the end face of the capillary to the end face of a capillary to be connected or to the end face of an opening of a fluid channel in a socket unit can be ensured in a simple manner that the capillary at its front end a Having in the radial direction over the inner diameter of the annular sealing element protruding loading area.
  • the sealing element is formed sufficiently elastically or plastically deformable to simultaneously ensure a seal of the plug capillary relative to the socket unit or the capillary receiving opening. The sealing takes place in the region of the radially outwardly extending loading region of the plug capillary, so that a dead volume is avoided.
  • the loading area has its largest diameter, preferably in the plane of the end face of the plug capillary or in its immediate vicinity, in order to avoid that material of the sealing element in an annular gap between the end face of the plug capillary and the end face of the Buchsenkapillare or the bottom of the Receiving opening in the socket unit presses, in which the Buchsenkapillarenö réelle is provided.
  • such a trained plug unit according to the invention can also be used for conventional known socket units with different, manufacturer-dependent hole depths for the capillary receiving opening.
  • the connector housing must be provided with connecting means that allow secure connection in any position within a correspondingly large axial tolerance range. This can be realized in a simple manner by a thread, in particular fine thread. The thread must of course be selected to match the socket unit.
  • a UNF10-32 thread use that satisfies this condition, however, or that is suitable for this purpose.
  • the loading region of the plug capillary can be designed to be rotationally symmetrical with respect to the longitudinal axis and preferably have an outer diameter which increases continuously in the direction of the end face of the plug capillary.
  • a trumpet-shaped or conical structure of an impingement region can be made by a simple upset of the front portion of a capillary.
  • a corresponding tool should have a mandrel that engages during the compression process in the channel opening of the capillary to maintain its inner diameter to the original value.
  • the loading area of the plug capillary may have radially outwardly extending arms.
  • the sealing element preferably has a bore for receiving the plug capillary, which substantially corresponds in the mounted state to the outer diameter of the plug capillary.
  • the sealing element may be designed so that it engages in the assembled state, the outer circumference of the male capillary with a radially inwardly directed bias.
  • the sealing element can be designed to facilitate the application to the plug capillary as a slotted ring element, which has sufficient elasticity to be either pushed from the front onto the plug capillary or laterally attached to the plug capillary.
  • the outer diameter of the sealing element is preferably formed larger than the outer diameter of the loading region of the plug capillary. In this way it can be ensured that a sealing effect also takes place in a region radially outside the end face of the plug capillary, for example by pressing the sealing element against the bottom of a corresponding receiving opening in the socket unit in a region radially outside the end face of the plug capillary.
  • the sealing element can be designed so that it positively encloses the loading area of the plug capillary with its front area in the unpressurised or de-energized state.
  • the front end face of the sealing element should not project beyond the end face of the plug capillary in the axial direction in order to prevent a Press the end face of the plug capillary to ensure an opposite end face on Stoli, and so to avoid dead volume.
  • the bore has an inner diameter which is only slightly larger than the outer diameter of the capillary, at least in a front region of the pressure piece. This avoids that at a high pressure, which is exerted by the pressure piece on the sealing element, material of the sealing element enters into the annular gap between the outer diameter of the plug capillary and the inner diameter of the axial bore of the pressure piece.
  • a pressure piece offers the advantage that no friction occurs between the sealing element and the pressure piece when using a screw connection between the connector housing and the socket unit, and consequently damage or impairment of the sealing element during the assembly process is avoided.
  • the use of a pressure piece allows the use of a uniformly shaped plug housing for different capillary diameters, in which case only the more easily produced pressure piece has to be adapted to the outer diameter of the capillary.
  • FIG. 1 shows a representation of the components of a first embodiment of a connection system according to the invention in longitudinal section
  • FIG. 2 shows an illustration of the connection system according to FIG. 1 in the mounted state
  • FIG. 3 shows an illustration of a further embodiment of a connection system according to the invention with a plug capillary consisting of two jacket layers in the mounted state
  • FIG. 4 is a perspective view of a slotted plug unit of another embodiment of a connection system, which are arranged together with a pressure piece and a sealing element on a plug capillary for mounting with a socket unit, and
  • Fig. 5 shows an embodiment of a connection system in which the plug unit is supplemented by a two-part housing, in which a filter is provided.
  • connection system 1 illustrated in the disassembled state in FIG. 1 comprises a socket unit 5, which is only schematically illustrated with respect to its outer contours which are not relevant to the invention and can be arranged, for example, on a component of a plant for high performance liquid chromatography, for example on a separation column.
  • the connector unit 3 in turn comprises a plug capillary 10, which may be made for example of stainless steel, realized in the form of a screw plug housing 20, a pressure piece 30 which as well as the connector housing 20 made of stainless steel or a may consist of other metal, and a sealing element 40, which may for example consist of a sufficiently elastic and / or plastically deformable material, for example a suitable plastic.
  • the helical connector housing 20 has a thickened, provided with a knurling 21 on the outer circumference of the head part, followed by a thread 22 provided with a threaded part.
  • the plug housing 20 has a stepped in the illustrated embodiment, central bore, wherein the inner diameter of the bore in the front region of the threaded portion is only slightly larger than the outer diameter of the recorded in the central bore plug capillary 10.
  • the plug capillary 10 extends through with its front end, the central Bore of the plug housing 20, wherein in the direction of the end of the plug capillary 10 in front of the plug housing 20, the pressure piece 30 is arranged radially around the plug capillary 10.
  • the Rear area corresponds to the outer diameter of the rotationally symmetrical pressure piece 30, the inner diameter of the receiving opening 53 of the female unit 5 in its rear, the plug unit 3 facing area.
  • the outer diameter must be slightly smaller than the inner diameter of the receiving opening 53, otherwise the pressure piece in the thread 52 jams. However, this must be as large as possible, so that the pressure piece on the connector housing is aligned as well as possible axially and the bore of the capillary 10 and the bore 57 are aligned as well as possible, so as not to disturb the flow.
  • the outer diameter of the front portion of the pressure piece 30 corresponds to the inner diameter of the receiving opening 53 in the inwardly directed cylindrical end portion 56 which is closed by the bottom wall 51 in which coaxially the Buchsenkapillarenö réelle 55 of the Buchsenkapillare 57 opens.
  • This outer diameter must also be slightly smaller than the inner diameter of the cylindrical end portion 56 of the receiving opening 53, so that the assembly and disassembly is not hindered.
  • the sealing element 40 is arranged in the direction of the end of the plug capillary 10, which is annular.
  • the end of the plug capillary 10 has a steadily increasing outer diameter, whereby an application region 11 is formed.
  • the maximum outer diameter of the loading area 11 is smaller than the inner diameter of the receiving opening 53 in its inner, cylindrical end area 56, which is delimited by the bottom wall 51.
  • the outer diameter of the sealing element 40 essentially corresponds to the inner diameter of this cylindrical, inner region of the receiving opening 53.
  • the inner diameter of the sealing element 40 is substantially complementary to the contour of the outer diameter of the loading area 11, so that the sealing element 40 can be pushed onto the loading area 11 without great pressure or without a large axial force.
  • the contour of the inner diameter in the front region of the sealing element 40 is, however, preferably designed so that the unpressurized pushing onto the loading area 11 takes place only up to an axial position can, in which the end face of the sealing element 40 is still set back by a certain amount relative to the end face of the Beauftschungs Schemes 11 and the plug capillary 10.
  • the plug housing 20, the pressure piece 30 and the sealing element 40 are first pushed from the front onto the plug capillary 10, which has no radially thickened Beaufschlagungs Suite 11 in this state. Subsequently, the loading region 11 can then be produced with a suitable tool, for example by upsetting or the like.
  • the Beauftschungs Scheme 11 of the male capillary 10 may already be made and in this case the remaining components of the plug unit 3 are pushed from the other end of the male capillary 10 to this.
  • the sealing element 40 can also be designed as a ring element slotted in the axial direction, so that the sealing element 40 can then be pushed onto the plug capillary 10 from the front, over the thickened loading area 11, or pushed onto the plug capillary 10 from the side.
  • the material of the sealing element 40 must of course have sufficient elasticity.
  • the plug unit 3 can then be inserted into the socket unit 5.
  • the insertion takes place in a simple manner in that the plug housing is pushed without force on the capillary 10 in the direction of the loading area 11, until the pressure piece 30 and the sealing element 40 are moved to their non-pressurized, front position. Subsequently or simultaneously, the plug unit 3 is inserted into the receiving opening 53 of the socket unit 5 and the thread 22 of the threaded part of the plug unit 20 is screwed into the internal thread 52 of the receiving opening 53. During screwing in, the front end face of the plug housing 20 exerts an axial force on the pressure piece 30 on the sealing element 40, which in turn exerts the axial force on the plug capillary 10 via the loading area 11.
  • the construction shown in the drawing of a plug unit 3 ensures even at different depths of the receiving opening 53 of the socket unit 5, that the end face of the plug capillary 10 is always positioned with a defined force against the bottom wall 51 of the receiving opening 53.
  • the plug housing 20 has to be unscrewed from the socket housing 50 and the plug capillary 10 together with the pressure piece 30 and the sealing element 40 are pulled out of the receiving opening 53.
  • the increase in diameter in the area of the loading area 11 of the plug capillary 10 ensures that the sealing element 40 is pulled out when the plug cap is being pulled out.
  • the male capillary 10 does not remain in the receiving opening 53, in particular the inner cylindrical region and then laboriously needs to be removed. If the plug unit 3 is subsequently to be mounted again, if necessary in another (similar) socket unit 5, the sealing element 40 can optionally also be exchanged.
  • the material for the sealing member 40 for example, PEEK or a material having suitable chemical and physical properties can be used.
  • FIG. 3 shows an illustration of a further plug unit 1 in the installed state, similar to FIG. 2, wherein the plug capillary 10 has an outer casing layer 12, which consists of a slightly plastically deformable material and which surrounds an inner casing layer.
  • the outer cladding layer may for example be made of plastic, which is thermally deformable, while the inner cladding layer consists of a material which is suitable for guiding the liquid in question, for example of stainless steel, glass, Fu- sed silica or other plastic.
  • these materials are also suitable as a material for a male capillary 10 having a single material wall (see, for example, the embodiment illustrated in Figures 1 and 2).
  • the inner cladding layer can also protrude beyond the trumpet-like deformed front part of the outer cladding layer 12, this protruding part being in the mounted state of the plug unit 1 in the part of the imager adjacent to the loading area 11 of the front area 56 of the receiving opening 53
  • Bushing housing trained channel can extend for the liquid to be supplied.
  • FIG. 4 shows a plug unit 5, in which the plug housing 20 has a radial slot 23, which allows the plug housing 20 to be pushed from the side onto the plug capillary 10, or the plug capillary 20 via the slot 23 into the space provided for this purpose coaxial mounting position within the connector housing 20 is used. This facilitates the assembly and disassembly and replacement of the connector housing 20th
  • connection system 1 shows an embodiment of a connection system 1 in which the plug unit 5 is supplemented by a two-part housing 60, 80, in which a filter (or a frit) 71 is provided.
  • the first, cup-shaped housing part 60 receives the disc-shaped filter 71, whose radially outer edge region between the end face of the second housing part 80 and the bottom of the first cup-shaped housing part 60 is held.
  • the outer edge area assumes a sealing function and can be made of a suitable material for this purpose.
  • the radially inner region of the filter 71 represents the actual filter region 70 and can be designed for this purpose in a manner known per se.
  • the second housing part 80 is formed in its rear region as the socket housing 50 and has a corresponding receiving opening 53.
  • the front portion of the first housing part 60 engages in the rear recess in the plug housing 20, wherein the plug housing 20 and the housing part 60 are preferably formed so that they are axially rotatably connected to each other. This can be done for example by a snap-in connection in the axial direction of the parts.
  • the male capillary 10 in this case is preferably solid and sealed to the housing 60, 80, in particular with the first housing part 60, for example, by welding, wherein the channel of the plug capillary 10 is fluidly connected to the receiving opening 53 in the second housing part 80 via a formed in the housing 60, 80 flow area in which the filter 71 is arranged , The plug capillary 10 must then be cut to length accordingly.
  • the rotatable connection of the plug housing 20 ensures that the capillary does not have to be rotated during assembly of the entire plug unit 5 (which in this case includes the housing 60, 80 and the frit 71) when the plug housing 20 is inserted into the receiving opening 53 of the female housing is screwed.
  • the filter can be quickly replaced or cleaned.

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  • Engineering & Computer Science (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Mechanical Engineering (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Stored Programmes (AREA)
  • Gasket Seals (AREA)

Abstract

L'invention concerne une unité de fiche (3) pour connecter des capillaires, en particulier pour la chromatographie en phase liquide à haute performance, avec un capillaire de fiche (10) qui fait saillie par un orifice d'un boîtier de fiche (20), le boîtier de fiche (20) étant conçu de manière à pouvoir être connecté de manière amovible à une unité de douille (5), l'extrémité avant du capillaire de fiche (10) faisant saillie dans l'état connecté de l'unité de fiche (3) et de l'unité de douille (5) dans une ouverture de réception de capillaire (53) de l'unité de douille (5) et faisant face avec sa surface frontale essentiellement alignée à une extrémité avant d'un capillaire de douille (57) ou à une ouverture de capillaire de douille (55) de l'unité de douille (5) et entrant en contact bord à bord avec sa surface frontale, et le boîtier de fiche (20) entrant indirectement ou directement en contact par sa surface frontale orientée vers l'extrémité du capillaire de fiche (10), dans l'état monté de l'unité de fiche (3) et de l'unité de douille (5), avec un élément d'étanchéité annulaire (40) entourant le capillaire de fiche (10) dans la zone de l'extrémité avant du capillaire de fiche (10) de telle manière que l'extrémité avant du capillaire de fiche (10) soit rendu étanche par une déformation élastique ou élastique et plastique de l'élément d'étanchéité (40) contre l'ouverture de réception de capillaire (53) de l'unité de douille (5). Selon l'invention, la surface avant de l'élément d'étanchéité annulaire (40) entre en contact, pendant le montage et dans l'état monté de l'unité de fiche (3) et de l'unité de douille (5), avec une zone de contact (11)de l'extrémité avant du capillaire de fiche (10) faisant saillie en direction radiale au-delà du diamètre intérieur de l'élément d'étanchéité radiale (40), le capillaire de fiche (10) étant mû pendant le processus de montage, si nécessaire, avec la surface frontale contre la surface frontale du capillaire de douille (57) ou l'ouverture de capillaire de douille (55) et étant pressée contre celle-ci à l'état monté.
EP09807486A 2008-12-02 2009-11-27 Unité de fiche et système de connexion pour connecter des capillaires, en particulier pour chromatographie en phase liquide à haute performance Withdrawn EP2361386A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE200810059897 DE102008059897B4 (de) 2008-12-02 2008-12-02 Steckereinheit und Verbindungssystem für das Verbinden von Kapillaren, insbesondere für die Hochleistungsflüssigkeitschromatographie
PCT/DE2009/001688 WO2010063267A1 (fr) 2008-12-02 2009-11-27 Unité de fiche et système de connexion pour connecter des capillaires, en particulier pour chromatographie en phase liquide à haute performance

Publications (1)

Publication Number Publication Date
EP2361386A1 true EP2361386A1 (fr) 2011-08-31

Family

ID=42035888

Family Applications (1)

Application Number Title Priority Date Filing Date
EP09807486A Withdrawn EP2361386A1 (fr) 2008-12-02 2009-11-27 Unité de fiche et système de connexion pour connecter des capillaires, en particulier pour chromatographie en phase liquide à haute performance

Country Status (5)

Country Link
US (2) US9134283B2 (fr)
EP (1) EP2361386A1 (fr)
CN (1) CN102239408B (fr)
DE (1) DE102008059897B4 (fr)
WO (1) WO2010063267A1 (fr)

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DE102011050037B3 (de) * 2011-05-02 2012-06-14 Dionex Softron Gmbh Steckereinheit und Verbindungssystem zum Verbinden von Kapillaren, insbesondere für die Hochleistungsflüssigkeitschromatographie
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DE102008059897B4 (de) 2010-09-16
US20110298210A1 (en) 2011-12-08
CN102239408B (zh) 2014-09-17
DE102008059897A1 (de) 2010-06-10
US9134283B2 (en) 2015-09-15
WO2010063267A1 (fr) 2010-06-10
CN102239408A (zh) 2011-11-09
US20150338000A1 (en) 2015-11-26
US9945501B2 (en) 2018-04-17

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