EP2313259B1 - Dispositif pour former des tablettes par compaction a volume constant - Google Patents

Dispositif pour former des tablettes par compaction a volume constant Download PDF

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Publication number
EP2313259B1
EP2313259B1 EP09780753.1A EP09780753A EP2313259B1 EP 2313259 B1 EP2313259 B1 EP 2313259B1 EP 09780753 A EP09780753 A EP 09780753A EP 2313259 B1 EP2313259 B1 EP 2313259B1
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EP
European Patent Office
Prior art keywords
compaction
punch
cam
punches
control means
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EP09780753.1A
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German (de)
English (en)
French (fr)
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EP2313259A1 (fr
Inventor
Max Linossier
Jacques Brosse
Philippe Eichler
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Eurotab SA
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Eurotab SA
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B30—PRESSES
    • B30B—PRESSES IN GENERAL
    • B30B15/00—Details of, or accessories for, presses; Auxiliary measures in connection with pressing
    • B30B15/16—Control arrangements for fluid-driven presses
    • B30B15/22—Control arrangements for fluid-driven presses controlling the degree of pressure applied by the ram during the pressing stroke
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B30—PRESSES
    • B30B—PRESSES IN GENERAL
    • B30B11/00—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses
    • B30B11/02—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses using a ram exerting pressure on the material in a moulding space
    • B30B11/08—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses using a ram exerting pressure on the material in a moulding space co-operating with moulds carried by a turntable

Definitions

  • the present invention relates to the field of tablet design from component mixing, in the form of powders or granules in particular, and more particularly to a press device for forming such tablets by compaction.
  • the existing devices for making tablets by compaction are conventionally rotary presses provided with a rotating central plate in which is formed a plurality of through dies.
  • On either side and facing each of the matrices are arranged lower and upper punches complementary to each other, and intended to be inserted into the corresponding matrix to compact the mixture it contains in order to form a compacted tablet at the desired volume.
  • the punches are provided with compaction ends whose surfaces define with the walls of the matrix a containment volume of the mixture, the punches being progressively closer to each other until reaching the compaction volume.
  • the actual compaction phase is carried out by compaction rollers on which the punches roll, and which allow to bring the punches instantaneously following a strong stress to form the tablet to the desired volume.
  • a device according to the preamble of claim 1 is for example described in the patent application EP1600285 .
  • the applicant has therefore sought to develop a rotary press for performing such compaction at constant volume. To do this it is necessary to keep the punches at a fixed compaction position so that the confinement volume (defined by the matrix and the lower and upper punches) is kept constant.
  • One solution is to use a particular compaction member composed of compacting rollers and ball bearings arranged to maintain the punches at a fixed axial position, and to lengthen the compaction.
  • Such a solution is however complex to implement, and it is not very precise since the axial position of the punches varies significantly with respect to the set position, as a function of the contact surface with the roller / bearing.
  • such a solution is not easily adaptable, particularly as regards the holding time punches.
  • An object of the present invention is therefore to provide a press adapted to maintain a compaction at a constant volume for a predetermined time to solve at least one of the aforementioned drawbacks.
  • an object of the present invention is to provide a press for maintaining a constant volume compaction easily adaptable to any type of product, rate, and holding time.
  • Yet another object of the present invention is to provide a press for maintaining a constant volume compaction that can be used at industrial rates, for increased productivity, and whatever the type of product to compact.
  • a press device for making tablets from a mixture of at least one component according to claim 1.
  • planar cam portion having an angular section of between 5 ° and 170 ° is particularly advantageous since it makes it possible to compact mixtures during compaction holding times of between 100 and 2500 ms, and this in a wide range. range of rotational speed of the press to ensure a good industrial rate.
  • the fact of being able to compact at various speeds of rotation makes it possible to compact any type of mixture during the compaction times indicated (between 100 and 2500 ms), including the mixtures requiring a reduced rotation speed of the press (of the order a dozen revolutions per minute).
  • the productivity is even better than such an angular section for the flat cam portion also allows to have a press comprising at least two outputs.
  • planar cam portion has a length furthermore implies that several punches are simultaneously on the cam path, which makes it possible to further increase the rate of formation of tablets according to a compaction cycle having a step of maintaining compaction. Indeed, if several punches are simultaneously on the flat cam portion, this implies that several tablets can be compacted simultaneously on the same flat cam portion with only a slight shift in the compaction cycle.
  • the figure 1 is a perspective sectional view of a rotary press device which makes it possible to illustrate the structure conventionally used to drive the compaction punches according to a rotary movement.
  • the rotary press device comprises a turret which is rotated by a known motorization system via a central drive axis.
  • the turret comprises a central plate 1 which comprises at least one compaction matrix 2, this matrix 2 being intended to receive a mixture of compounds from which it is desired to form a compacted tablet at a determined volume.
  • the central plate preferably comprises a plurality of matrices 2 distributed for example at the periphery of the central plate 1 which has a substantially circular shape.
  • Said matrices 2 have a generally cylindrical shape and are either formed by a through hole directly formed at the periphery of the central plate 1, or each die is a specific part comprising a cylindrical through central opening having a circular section with a determined diameter corresponding to the desired diameter for the tablet, this piece serving as a matrix having an external shape adapted to be inserted into through openings formed at the periphery of the central plate 1.
  • the press device comprises punches (not shown on the figure 1 ) which are arranged on either side of each of the dies 2 of the central plate 1.
  • the device comprises a lower pair of punches 3 and upper 4 for each of the matrices 2 of the device.
  • the lower and upper punches 4 are mounted in the press so as to be axially displaceable with respect to the corresponding die 2, so that said lower and upper punches 4 can be inserted into the die 2 to compress the mixture disposed at the inside of the matrix to form a tablet at a determined volume.
  • the lower 3 and upper 4 punches are also mounted in the press so as to have a circular movement corresponding to the circular movement of the matrix 2 with which they are associated.
  • a solution for setting the punches in motion along this circular path is to use training plates 5 and 6 located on either side of the central plate 1, these two training plates 5 and 6 being integral with the central plate. 1 and thus being also rotatably mounted in the press.
  • the drive plates 5 and 6 are provided with through openings disposed at their periphery, these through openings being intended to receive the lower punches 3 and upper 4 respectively.
  • the lower and upper punches 4 are thus rotated by the drive plates 5 and 6, respectively, synchronously with the corresponding die 2, the lower and upper punches 4 being moreover able to slide in the openings provided at the periphery. drive trays 5 and 6 so that the compaction ends 31 and 41 of the lower and upper punches 3 and 4 can be inserted into the die 2.
  • the axial displacement of the lower 3 and upper 4 punches is controlled by lower control means 7 and upper control means 8 respectively, these lower 7 and upper 8 control means being intended to cooperate with the guide ends 32 and 42 of the punches lower 3 and upper 4 respectively.
  • the control means are intended to move the corresponding punches along the axis of the die so as to modify the axial position of the punch (and more particularly the axial position of the compaction end of the punch) according to the operating cycle of the press.
  • the axial position of a punch is defined as the position of the punch in the axis of the die, this position thus making it possible to characterize the axial displacement of the punch, but also the associated confinement volume.
  • the lower control means 7 and upper 8 are adapted to cooperate so as to maintain, for a predetermined time, the lower 3 and upper 4 punches in an axial fixed compaction position in which these lower 3 and upper 4 punches define with the matrix 2 associated a fixed confinement volume corresponding to the compaction volume adapted to form a tablet with a certain volume.
  • the compaction volume is substantially equal to the final volume sought for the tablet.
  • the compaction volume corresponds to the final volume sought for the tablet. It may, however, in certain cases be possible for the compaction volume to be slightly less than the final volume desired for the tablet; this is for example the case when tablet compressed compounds still have a certain elasticity.
  • one of the two control means comprises a particular compaction cam.
  • the lower control means 7 for moving the lower punches 3 comprise said particular compaction cam.
  • This description is however not limiting since a compaction cam as described below could also be used for the upper control means 8, or both for the lower control means 7 and upper 8.
  • the compaction cam 9 comprises a cam path on which the corresponding punches are able to move, this cam path having a trajectory corresponding at least partially to the circular trajectory defined by the movement of the matrices 2.
  • Said compaction cam 9 comprises a flat portion 90 substantially perpendicular to the axis of the punch 3 which moves on the cam.
  • a punch that moves on this flat cam portion 90 has a fixed axial position maintained for a predetermined time.
  • the flat portion 90 extends over an angular section which is adapted to maintain the punch inserted in the die 2 at the desired fixed position, to maintain a constant compaction volume during a holding time. determined.
  • the angular section of the planar cam portion is defined as the angle formed by the planar cam portion relative to the center of the circular path of the punches.
  • the length of the flat cam portion is further defined as the distance traveled by the punch on said flat cam portion when the punch is rotated by the associated drive plate.
  • the dimensioning of the flat cam portion 90 depends on the time during which it is desired to maintain the compaction volume constant, and the rotational speed at which the punches are driven in the press.
  • the hold time of the constant volume compaction of conventional systems is less than 30 ms (milliseconds).
  • the rotational speeds for a rotary press used in production are between 18 and 30 revolutions / minute, which corresponds to flat cam portions with an angular section of 3.24 ° and 5.4 ° respectively, for a time compaction hold at constant volume of 30 ms.
  • the angular section of the planar cam portion necessary for 30 ms constant volume compaction is reduced; it is for example 0.36 ° for a rotation speed of 2 revolutions / minute.
  • the angular section of the planar cam portion will be larger the longer it is desired to maintain constant volume compaction (for a given rotational speed of the press).
  • the compaction cam 9, and in particular the flat cam portion 90 is adapted as a function of the time during which it is desired to maintain the compaction at constant volume, but also as a function of the operating parameters of the press (rotation speed, diameter , etc.).
  • planar cam portion to maintain a constant compaction volume is all the more advantageous as it is very simple to adapt and / or set up a new cam in the press.
  • rotational speed of the press can also be modified to achieve the desired holding time for a flat cam portion having a given length (and thus a given angular section).
  • the upper control means 8 are also adapted to maintain the upper punch 4 in a fixed axial position while the lower punch 3 is held in fixed axial position by cooperation with the flat cam portion 90.
  • the control means upper members 8 comprise a compaction cam 10 having a flat cam portion 100 extending over an angular section at least equal to the angular section of the cam portion 90 of the compaction cam 9.
  • any other means for maintaining fixed axial position of the upper punch 4 may be considered. It could for example be used a system of upper punches 4 whose axial displacement is prohibited, the upper punches 4 being then held in the matrix 2 at a defined fixed axial position. It could also be envisaged to have a press device with only lower punches 3 intended to be inserted in non-through matrices 2, that is to say having a "blind hole” type opening.
  • the fact that the lower punch 3 moves on the flat cam portion 90 for a predetermined time implies that the compaction end 31 of the lower punch 3 is held in the die 2 at a fixed axial position for a predetermined time, the compaction end 41 of the upper punch 4 also being held in the die 2 at a fixed axial position , so that the lower punch 3, the upper punch 4 and the die 2 form a confinement volume held fixed for the same determined time, this confinement volume corresponding to the compaction volume adapted to form the tablet.
  • the different elements of the press device are adjusted so that the lower and upper punches 4 define with the matrix 2, during this compaction holding time, a fixed compaction volume corresponding to the final volume of the Tablet.
  • the guide end 32 of the lower punch 3 is formed so that said lower punch 3 can move on the compaction cam 9 so as to be able to respond to compaction constraints to form the desired tablet.
  • the punches must be able to withstand the forces induced by the compaction of the mixture, and the friction forces are reduced to a minimum.
  • the sum of the forces induced by the punches during compaction generates a significant torque in the training of the turret.
  • the use of standard punches requires the mounting of a motor with a much larger torque and therefore a dimension, intensities, powers much larger.
  • the friction generated by the set of punches emit, when standard, a significant heat energy and a rapid degradation of the cams.
  • a guide end 32 comprising a roller 33 arranged so that the lower punch 3 can roll on the cam path of the compaction cam 9 along the partially circular path defined.
  • the rolling roller 33 is arranged coaxially with the axis of the lower punch 3 at its guide end 32, with an axis of rotation that is radial relative to the axis of the punch.
  • the use of such a rolling roller 33 makes it possible to considerably reduce the friction caused by the displacement of the lower punch 3 on the compaction cam 9, which is particularly advantageous for maintaining compaction stresses large, typically greater than 1 KN (kilo-Newton), for prolonged holding times in compaction compared to conventional rotary press systems.
  • the rolling roller 33 is sized according to the stress constraints to which the press device is subjected. It can therefore be adapted according to the composition of the mixture to be compacted.
  • the dimensioning of the rollers must make it possible to accept the axial forces without degrading the cam surface on which they roll (lifespan compatible with the maintenance aspects) while allowing a mounting of punches in sufficient number to maintain a good productivity per revolution. turret.
  • the compaction cam 9 may further comprise a pressure increase portion 91 and a pressure descent portion (not shown).
  • the pressure increase portion 91 is situated upstream of the planar holding portion 90, this pressure increase portion 91 being adapted to move the lower punch 3 into the direction of insertion in the matrix 2 until the axial position corresponding to the fixed axial position of compaction holding defined by the plane portion 90 compaction maintaining.
  • the pressure rise portion 91 makes it possible to progressively move the lower punch in the die 2, and it is adapted to prepare the mixture for the final compaction.
  • the compaction cam 9 may also comprise a pressure descent portion situated downstream of the planar holding portion 90, again with reference to the direction of rotation of the punches in the press device.
  • This pressure descent portion 92 serves to reduce the compaction volume defined by the lower punch 3, the upper punch 4 and the die 2.
  • this pressure descent portion is preferably arranged so as to move the punch axially. lower 3 as well as the upper punch 4 for extraction of the upper compaction end 4 of the matrix 2.
  • This pressure descent portion is however not necessary since the reduction of the confinement volume (defined by the lower punch 3, the upper punch 4 and the matrix 2) can be effected by an axial displacement of the upper punch 4 in order to From a particular embodiment, the planar portion 90 of compaction of the compaction cam 9 can even be followed by a cam portion 11 arranged to axially move the lower punch 3 to increase. its insertion into the die 2.
  • a cam portion 11 may be called an extraction cam, arranged to expel out of the die 2 the tablet formed during the compaction phase by the compaction-holding cam 90, in such a way that to recover this tablet and to be able to refill the matrix 2 with the mixture of compounds before reforming a new tablet.
  • the lower control means 7 further comprise the compaction cam 9 which makes it possible to manage the axial displacement of the lower punch 3 during the compaction phase strictly speaking, guiding means enabling the punch to be moved axially. lower 3 during other phases of the cycle of operation of the press.
  • the extraction cam 11 is a particular example of such additional guide means, this extraction cam 11 being used to push the tablet out of the die 2 during the extraction phase following the compaction phase.
  • the lower control means may also include a metering cam with a particular cam path for moving the lower punch 3 adequately during filling of the die 2 with the compound mixture. It is arranged upstream of the compaction cam 9, preferably immediately before said compaction cam 9.
  • the lower control means 7 may also comprise other guide members allowing, for example, the lower punch 3 to be displaced between the different important phases of the operating cycle of the press, in order to put the punches in position.
  • the lower punch 3 may for example be provided with guide rollers 34 arranged coaxially with the axis of said punch with an axis of rotation radial relative to this punch, the two guide rollers 34 being located from and other punch.
  • the guide rails 12 are provided with a groove in which the guide rollers 34 can roll. It is the cooperation of these guide rollers 34 in the grooves which makes it possible to axially move the lower punch 3.
  • the figure 4 illustrates an example of a cam for the punch control means.
  • the cam shown in plan view comprises a first cam portion 13 (in the direction of rotation of the punches) corresponding to the metering cam, this metering cam 13 being followed by a pressure increase cam portion 91, then of the pressure maintaining cam portion 90.
  • the arrow represented on this figure 4 illustrates the direction of movement of the punches on the cam.
  • the figure 5 illustrates a device in which the lower control means 7 comprise cams with cam portions similar to the cam shown in FIG. figure 4 that is, a metering cam portion 13, a pressure rise cam portion (91), and a compaction holding cam portion (90).
  • the upper control means also includes a planar cam portion (100) for holding the punch in position during compaction, which planar cam is also preceded by a pressure rise cam (101).
  • the arrow represented on this figure 5 illustrates the direction of movement of the punches on the cams.
  • the figure 5 illustrates a particular embodiment of the press device shown wherein the lower control means 7 and upper 8 both comprise a planar portion for maintaining compaction, and a pressure increase portion.
  • the upper punches 4 have a structure similar to the lower punches, and they include in particular preferably at least one roller (43), or even guide rollers (44).
  • the upper control means 8 are in this particular case provided with means adapted to retain the upper punches 4 against the effect of gravity.
  • the figure 5 also makes it possible to illustrate the movement of the lower and upper punches 4 inside the matrix 2 during their displacement on the cams of the lower and upper control means 7 and 8. It can thus be seen that the volume (V) is progressively reduced when the punches roll on the pressure increase cams (91; 101) while the same containment volume (V) remains fixed (at a compaction volume substantially corresponding to the final volume of the tablet) when the punches roll on the compaction maintaining cams (90; 100).
  • At least one of the compaction cams comprises sensors making it possible to follow the compaction stress defined by the action of the lower 3 and upper 4 punches on the mixture of compounds to be compressed. It is also possible to provide distance sensors for monitoring the axial position of the lower and / or upper punches 4.
  • these stress sensors are particularly advantageous for monitoring the behavior of the mixture of compounds when it is compacted at a constant volume for a predetermined time.
  • these stress sensors can in particular be used to determine and / or adjust the compaction cycle to be applied to the mixture to be compacted.
  • the sensor measures the effort of a single punch and the passage of each punch; unlike a stress sensor associated with a compression roller which measures the sum of the forces of the punches in contact with this roller.
  • strain sensors can be used to control the proper operation of the press and punches.
  • stress sensors can be used to prevent any disturbance of the press, particularly as regards the positioning of the cam paths (parallelism, relative difference, etc.), and / or by controlling the compaction at strategic points. of the compaction cycle.
  • the press of the invention for the compaction of pulverulent compositions comprising at least one powder having elastic properties or hot-melt properties, but also to the compaction of pulverulent compositions having a tendency to change state during compaction. for example passing from a solid state to a pasty or liquid state. They may be pulverulent compositions having a high moisture content.
  • elastic is meant a material that has the property to take back, partially or totally, its shape or its volume, after having lost by compression or extension.
  • hot melt is meant a material that becomes fluid under the effect of heat.
  • the press is used to compact powder compositions consisting of a powder or a mixture of powders, at least one of which has elastic or hot-melt properties.
  • the press is used for the compaction of pulverulent compositions based on plant materials.
  • the compaction can be implemented with plant ingredients such as coffee, tea or chicory or plant ingredients suitable for making herbal teas such as thyme, rosemary, linden, ginseng, ginko, marjoram, mint, verbena, ginger, wild yam, plants of the rosmarinus officinalis family, and mixtures thereof.
  • the plant compounds used in the invention are generally in the form of grains or broken or crushed leaves, and having optionally undergone one or more prior treatment known per se.
  • the process according to the present invention can in particular be applied to materials such as cellulose, hemicellulose, lignin or any mixture of the above compounds.
  • the invention can also be applied to wood fibers, algae, tea, aromatic herbs, stems of dry crushed plants, compost, dried flowers. (to be completed by other plant materials)
  • the press is used for the compaction of laundry washing compositions.
  • These compositions typically comprise: sequestering agents, alkaline agents, bleaching agents, surfactants (in liquid, solid form, supported on zeolites, bentonites or clays in general) anionic, cationic or nonionic, activators of the bleaching agent, enzymes, splitting agents, perfume binders, dyes, defoamers, optical brighteners, anti-blocking agents color transfer (to be completed by main ingredients) of which (to be supplemented by elastic ingredients) cellulose-type bursting agents have elastic properties, binding agents eg solid polyethylene glycol, solid surfactants type SDS, or supported liquid surfactants on bentonite have hot melt behaviors.
  • the press shown is used for the compaction of compositions for washing dishes.
  • the presented press makes it possible to progressively compact an initial volume of powder until a desired volume of compaction is reached at which the powder is maintained for a given time. This makes it possible to obtain a solid compact product from a powdery composition.
  • the punches are moved by the compaction cam 9 to progressively compact the pulverulent composition to the compaction volume that it is desired to maintain constant.
  • the compaction volume is smaller than the initial volume of the uncompacted powder composition.
  • the compaction volume is less than or equal to the determined or final volume of the compacted product. Indeed, as has already been said, when the powdery composition is particularly elastic, there may be a slight extension of the product during release of the volume constraint.
  • the compaction volume is between 20 and 90% of the initial volume of the pulverulent composition, and preferably between 30 and 75% of the initial volume.
  • the particular structure of the press makes it possible to maintain the pulverulent composition at a constant volume which corresponds to the compaction volume for a given time.
  • the time at which a constant compaction volume is maintained is chosen according to the characteristics required for the final compacted tablet.
  • the hold time can be determined experimentally.
  • the press When the compaction volume is kept constant, the press, and more precisely the punches and the associated compaction cams, are subjected to stress stresses due to the strength of the pulverulent composition.
  • the resistance of the powdery composition gradually decreases, stress constraints on the press thus decreasing concomitantly.
  • the measurement of these stress stresses during constant volume compaction makes it possible to determine the compression curve of a given pulverulent composition and to deduce the minimum time during which the composition must be maintained at the constant compaction volume.
  • This measurement can be done on a laboratory press.
  • the press according to the invention can also be used to make this particular measurement, provided that there are enough stress sensors arranged in the pressure holding cams.
  • roasted and milled coffee of average size 1 mm, with a loss of 4% volatile matter after a stay of 20 minutes at 120 ° C, is compacted using a compaction system to arrive at a constant controlled volume.
  • the punch used for this compression is a round punch of diameter 32 mm with chamfer. 7 grams of this product are introduced into the containment chamber representing a filling height of 27.3 mm. The final compression height is set at 8.3 mm leading to a volume reduction of 70%.
  • This compression height is maintained for a time of 850 milliseconds.
  • the maximum effort measured is 40KN, and only 20 KN after 850 milliseconds of hold time. We can therefore deduce that it is necessary to ensure a holding time in order to obtain a cohesive tablet. In this case the minimum hold time to obtain a cohesive and transportable tablet is 850 milliseconds. At 850 milliseconds the resulting force is 20 KN. The fall of this holding force is equal to 50%.
  • the press is dimensioned and / or adjusted so that it can maintain a compaction volume for a time of at least 850 milliseconds, and withstand forces of the order of 40 KN.
  • a compression cam having an angular section of at least 56.1 °, for a press having a rotational speed of 11 rpm.
  • the punches preferably have a roller having a diameter of 62 mm, and a width of 56 mm.
  • the punch used for this compression is a round punch of diameter 32 mm with chamfer. 7 grams of this product are introduced into the containment chamber representing a filling height of 27.3 mm. The final compression height is set at 8.3 mm leading to a volume reduction of 70%. This compression height is maintained for 800 milliseconds.
  • the maximum effort measured is 40 KN, and only 20 KN after 800 milliseconds of hold time. We can therefore deduce that it is necessary to ensure a holding time in order to obtain a cohesive tablet.
  • the minimum hold time for a cohesive and transportable tablet is 400 milliseconds. At 400 milliseconds the resultant force is 30 KN. The fall of this holding force is equal to 25%.
  • the press is dimensioned and / or adjusted so that it can maintain a compaction volume for a time of at least 400 milliseconds, and withstand forces of the order of 40 KN.
  • a compression cam having an angular section of at least 43.2 ° is used for a press having a rotation speed of 18 rpm.
  • the punches preferably have a roller having a diameter of 62 mm, and a width of 56 mm.
  • a Eurotab® linen formulation called 30458 is tested in order to check whether it is necessary to maintain a constant volume maintenance time to obtain a cohesive and transportable tablet.
  • the composition to be compacted is indicated in Table 1 below: ⁇ i> Table 1 - composition of laundry formulation 30458 (Eurotab company ⁇ / i> ® ⁇ i>) ⁇ / i> COMPOUNDS % by weight Sequestering agents (phosphates, citrate, polymers, zeolite ”) 35-50% Alkaline agents (sodium silicate, carbonate) 10-30% Charge (bicarbonate, sodium sulfate ...) 3-20% Nonionic and anionic surfactants 10-18% enzymes 0.5-3% Bleaching agents and activator 10-20% Binder (polyethylene glycol powder ...) 1-5% Disintegrating agents (cellulose %) 2-8% Optical brightener 0-1% Anti foam 0-1% perfume 0.5% - 1% dye 0.05% -0.1%
  • the press is dimensioned and / or adjusted so that it can maintain a compaction volume for a time of at least 100 milliseconds, and withstand stresses of the order of 32 KN.
  • a compression cam having an angular section of at least 10.8 ° is used for a press having a rotation speed of 18 rpm.
  • the punches preferably have a roller having a diameter of 62 mm, and a width of 56 mm.
  • ARBOCEL TM TF415 (cellulose), marketed by Rettenmaier®, is tested in order to check whether it is necessary to maintain a constant volume hold time to obtain a cohesive and transportable tablet.
  • a round punch of diameter 32 mm with chamfer is used. 8.45 grams of this ARBOCEL TM TF415 are introduced into the compaction chamber representing a filling height of 28 mm. The final compression height is fixed at 9 mm, resulting in a volume reduction of 68%. This compression height is maintained for 800 milliseconds. The maximum effort measured is 21 KN, and only 8 KN after 800 milliseconds of hold time. We can therefore deduce that it is necessary to ensure a holding time in order to obtain a cohesive tablet. In this case the minimum hold time to obtain a cohesive and transportable tablet is 300 milliseconds. At 300 milliseconds the resulting force is 18 KN. The fall of this holding force is equal to 14.3%.
  • the press is dimensioned and / or adjusted so that it can maintain a compaction volume for a time of at least 300 milliseconds, and withstand stresses of the order of 21 KN.
  • a compression cam having an angular section of at least 19.8 ° is used for a press having a rotation speed of 11 rpm.
  • the punches preferably have a roller having a diameter of 62 mm, and a width of 56 mm.
  • planar cam to maintain compaction is particularly advantageous so that the press has high production rates.
  • the use of the planar compacting cam keeps compaction for a relatively long time, for example of the order of 800 ms or even 2500 ms, without the rate of formation of tablets. by the press is reduced.
  • the use of holding cams implies that several punches are simultaneously on the cam path, and therefore that several tablets can be compacted simultaneously on the same flat cam portion, with only a slight shift in the compaction cycle.
  • Table 2 illustrates the minimum angular sections of the flat cam portion, for different holding times of the constant volume compaction, and for different rotational speeds of the press. These values are of course not limiting and the section of the flat cam portion will be adapted as a function of the desired time to maintain the compaction at a constant volume; the angular section of the flat cam portion can therefore be between these values or be larger, for a given rotation speed. The reasoning is the same if the speed of rotation of the press is changed.
  • the sizing of the press and the associated flat cam portion depends on the particular industrial constraints to make the tablets at the desired volume.
  • the flat cam portion must have an angular section necessarily less than 180 °, preferably less than 170 °.
  • the speed of rotation of the press is then adjusted according to the angular section selected for the flat cam portion to have the desired holding time for constant volume compaction.
  • the dimensioning of the flat cam portion can also be imposed by the operating constraints of the press (limiting rotational speeds).
  • limiting rotational speeds For a standard production press having a rotation speed of between 18 and 30 revolutions / minute, a flat cam portion having an angular section greater than 3 ° and 5 ° respectively, and preferably greater than 10 °, is used. 18 ° respectively.
  • rotational speeds of the press between 18 and 30 rpm are generally preferred to ensure a good rate, it may be necessary to reduce this speed of rotation depending on the composition of the mixture to be compacted, and its behavior at course of compaction.
  • speed of rotation of the press it is not uncommon for the speed of rotation of the press to be set around around ten revolutions per minute.
  • the press rotates at a speed at least equal to 5 revolutions / minute, and preferably at a speed greater than 8 revolutions / minute.
  • a planar cam portion having an angular section of between 5 ° and 170 ° is used, which makes it possible to compact mixtures for compaction keeping times of between 100 and 2500 ms, and this according to a wide range of speed of rotation of the press to ensure a good industrial rate.
  • the fact of being able to compact at various speeds of rotation makes it possible to compact any type of mixture during the compaction times indicated (between 100 and 2500 ms), including the mixtures requiring a reduced rotation speed of the press (of the order a dozen revolutions per minute).
  • the productivity is even better than such an angular section for the flat cam portion also allows to have a press comprising at least two outputs.
  • a flat cam portion having an angular section of between 35 ° and 90 ° is used.
  • Such a flat cam makes it possible to compact mixtures during compaction holding times of the order of 800 ms (plus or minus 50 ms) at high rotational speeds of the press. This makes it possible to operate at speeds of between 8 and 18 revolutions / minute, thus offering the possibility of compacting mixtures of various compositions. In addition, it also increases the number of outputs, by putting at least three if desired.
  • a press with plane compacting cam portions having an angular section of approximately 52 ° makes it possible to configure the press to have two outputs, with about fifty pairs of punches. circulating at the same time in the press, which allows a production of nearly 1100 tablets of coffee per minute (with a speed of rotation of 11 revolutions / minutes, for a compaction time of about 800 ms).

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  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Medicinal Preparation (AREA)
EP09780753.1A 2008-07-18 2009-07-17 Dispositif pour former des tablettes par compaction a volume constant Not-in-force EP2313259B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0854917A FR2933897B1 (fr) 2008-07-18 2008-07-18 Dispositif pour former des tablettes par compaction a volume constant
PCT/EP2009/059205 WO2010007152A1 (fr) 2008-07-18 2009-07-17 Dispositif pour former des tablettes par compaction a volume constant

Publications (2)

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EP2313259A1 EP2313259A1 (fr) 2011-04-27
EP2313259B1 true EP2313259B1 (fr) 2017-05-24

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US (2) US8764430B2 (enrdf_load_stackoverflow)
EP (1) EP2313259B1 (enrdf_load_stackoverflow)
JP (1) JP2011528282A (enrdf_load_stackoverflow)
BR (1) BRPI0916227A2 (enrdf_load_stackoverflow)
CA (1) CA2730157C (enrdf_load_stackoverflow)
FR (1) FR2933897B1 (enrdf_load_stackoverflow)
WO (1) WO2010007152A1 (enrdf_load_stackoverflow)

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DE202023101264U1 (de) 2023-03-15 2024-06-21 Romaco Kilian Gmbh Rundläufer-Tablettenpresse und Druckschiene als Kurvenabschnitt einer Steuerkurve für die Stempel eines Rotors der Rundläufer-Tablettenpresse

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US20120258156A1 (en) 2011-04-06 2012-10-11 Evan Rumberger Shaped compositions for uniform delivery of a functional agent
FR2990377B1 (fr) * 2012-05-11 2015-03-13 Eurotab Support de poincon pour machine de compactage
FR3008405A1 (fr) 2013-07-15 2015-01-16 Lhoist Rech & Dev Sa Composition comprenant un ou des composes calco-magnesiens sous forme de compacts
ITMO20130324A1 (it) 2013-11-29 2015-05-30 Sacmi Apparato di formatura
DE102017130885B4 (de) * 2017-12-21 2020-01-23 Fette Compacting Gmbh Verfahren zum Regeln der Rotordrehzahl eines Rotors einer Rundläufertablettenpresse sowie Rundläufertablettenpresse
CN108572602B (zh) * 2018-07-23 2024-03-15 上海海得控制系统股份有限公司 一种压片机的控制装置
EP4363208A4 (en) * 2021-07-02 2025-04-30 Industrial Pharmaceutical Resources, Inc. ROTARY TABLET PRESS WITH MULTI-ROW TURRET

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US4121289A (en) * 1975-05-28 1978-10-17 Hoffmann-La Roche Inc. Method invoking tabletting compression force control for optimizing tabletted formulation parameters
FR2629712A1 (fr) * 1988-04-08 1989-10-13 Bordeaux Ii Inst Pharmacie Ind Dispositif permettant d'ameliorer les caracteristiques mecaniques des comprimes obtenus sur des machines a cadence elevee
GB2343862A (en) * 1998-11-18 2000-05-24 Univ Bath A part for use in a moulding apparatus

Cited By (2)

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Publication number Priority date Publication date Assignee Title
DE202023101264U1 (de) 2023-03-15 2024-06-21 Romaco Kilian Gmbh Rundläufer-Tablettenpresse und Druckschiene als Kurvenabschnitt einer Steuerkurve für die Stempel eines Rotors der Rundläufer-Tablettenpresse
WO2024189512A1 (de) 2023-03-15 2024-09-19 Romaco Kilian Gmbh Rundläufer-tablettenpresse und druckschiene als kurvenabschnitt einer steuerkurve für die stempel eines rotors der rundläufer-tablettenpresse

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US20140314891A1 (en) 2014-10-23
BRPI0916227A2 (pt) 2015-11-03
JP2011528282A (ja) 2011-11-17
US8764430B2 (en) 2014-07-01
FR2933897B1 (fr) 2011-05-20
FR2933897A1 (fr) 2010-01-22
US20110142978A1 (en) 2011-06-16
EP2313259A1 (fr) 2011-04-27
CA2730157A1 (fr) 2010-01-21
WO2010007152A1 (fr) 2010-01-21
CA2730157C (fr) 2016-08-23

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