EP2242701B1 - Stopper device comprising a supporting cap, and container provided with such a device - Google Patents
Stopper device comprising a supporting cap, and container provided with such a device Download PDFInfo
- Publication number
- EP2242701B1 EP2242701B1 EP09710963A EP09710963A EP2242701B1 EP 2242701 B1 EP2242701 B1 EP 2242701B1 EP 09710963 A EP09710963 A EP 09710963A EP 09710963 A EP09710963 A EP 09710963A EP 2242701 B1 EP2242701 B1 EP 2242701B1
- Authority
- EP
- European Patent Office
- Prior art keywords
- cover
- cap
- neck
- ring
- container
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 210000002105 tongue Anatomy 0.000 claims description 30
- 230000002093 peripheral effect Effects 0.000 claims description 14
- 230000000903 blocking effect Effects 0.000 claims description 9
- 230000000295 complement effect Effects 0.000 claims description 7
- 230000000694 effects Effects 0.000 claims description 5
- 238000006243 chemical reaction Methods 0.000 claims description 4
- 229920003023 plastic Polymers 0.000 claims description 4
- 239000004033 plastic Substances 0.000 claims description 4
- 230000007423 decrease Effects 0.000 claims description 3
- 229920001971 elastomer Polymers 0.000 claims 1
- 239000000806 elastomer Substances 0.000 claims 1
- 239000000463 material Substances 0.000 claims 1
- 238000006073 displacement reaction Methods 0.000 description 10
- 238000004519 manufacturing process Methods 0.000 description 4
- 239000000470 constituent Substances 0.000 description 3
- 238000004891 communication Methods 0.000 description 2
- 230000018044 dehydration Effects 0.000 description 2
- 238000006297 dehydration reaction Methods 0.000 description 2
- 230000000881 depressing effect Effects 0.000 description 2
- 239000006185 dispersion Substances 0.000 description 2
- 238000004108 freeze drying Methods 0.000 description 2
- 238000009434 installation Methods 0.000 description 2
- 238000007789 sealing Methods 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 210000003679 cervix uteri Anatomy 0.000 description 1
- 230000006835 compression Effects 0.000 description 1
- 238000007906 compression Methods 0.000 description 1
- 230000000994 depressogenic effect Effects 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 238000001704 evaporation Methods 0.000 description 1
- 230000008020 evaporation Effects 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 239000007789 gas Substances 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000006193 liquid solution Substances 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 238000004806 packaging method and process Methods 0.000 description 1
- 239000000825 pharmaceutical preparation Substances 0.000 description 1
- 229940127557 pharmaceutical product Drugs 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 238000004321 preservation Methods 0.000 description 1
- 238000003825 pressing Methods 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 238000000859 sublimation Methods 0.000 description 1
- 230000008022 sublimation Effects 0.000 description 1
- 238000001291 vacuum drying Methods 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Images
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D51/00—Closures not otherwise provided for
- B65D51/24—Closures not otherwise provided for combined or co-operating with auxiliary devices for non-closing purposes
- B65D51/241—Closures not otherwise provided for combined or co-operating with auxiliary devices for non-closing purposes provided with freeze-drying means
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D45/00—Clamping or other pressure-applying devices for securing or retaining closure members
- B65D45/32—Clamping or other pressure-applying devices for securing or retaining closure members for applying radial or radial and axial pressure, e.g. contractible bands encircling closure member
- B65D45/322—Clamping or other pressure-applying devices for securing or retaining closure members for applying radial or radial and axial pressure, e.g. contractible bands encircling closure member the clamping device being an annular member moved axially to clamp the closure by using radial pressure
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D51/00—Closures not otherwise provided for
- B65D51/18—Arrangements of closures with protective outer cap-like covers or of two or more co-operating closures
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D2251/00—Details relating to container closures
- B65D2251/0003—Two or more closures
- B65D2251/0006—Upper closure
- B65D2251/0028—Upper closure of the 51-type
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D2251/00—Details relating to container closures
- B65D2251/0003—Two or more closures
- B65D2251/0068—Lower closure
- B65D2251/0075—Lower closure of the 39-type
Definitions
- the invention relates to a closure device for a container provided with a neck, and a container equipped with such a device.
- a glass vial In the field of medication containers, it is known to use a glass vial to preserve an active ingredient in the form of a freeze-dried powder or liquid solution. Such a bottle, as mentioned in WO 2005/000703 or FR 2893922 must be sealed in order to maintain its contents in a satisfactory state of preservation until its date of use.
- a closure device which comprises an elastomeric stopper whose function is to ensure a complete seal to gases, liquids and bacteria.
- This device also includes a locking cap which, as mentioned in FR 2 900 131 , US 5,678,719 or US 5,421,469 can be made of plastic and which is intended to be immobilized around the cap to isolate it from the outside and to obstruct its removal.
- each container is filled with a quantity of product to be freeze-dried and the stopper is placed on the neck of the container so as to be secured to it. while preserving communication between the outside environment and the interior of the container.
- the containers thus filled and prebunched are arranged in batches on the shelves of a lyophilizer inside which the products will be dehydrated.
- a vacuum drying is carried out which ensures the extraction of water from the product by sublimation and evaporation.
- the invention more particularly intends to remedy by proposing a closure device by means of which a locking force of a cap can be efficiently transmitted, including taking into account the manufacturing tolerances of the bottles, the plugs. , constituent parts of a cap and mechanical organs for applying a force.
- the closure device is characterized in that the connecting web, on the one hand, is elastically deformable so as to allow, under the effect of an axial force, an axial displacement of the support edge from a raised position R to a lowered position A through an intermediate position I, on the other hand, and has on a first range of deformation, corresponding to a displacement of the support edge between the raised position R and the intermediate position I, a stiffness K 1 greater than the stiffness K 2 of the web on a second range of deformation corresponding to a displacement of the support flange between the intermediate position I is the lowered position A.
- the connecting web is adapted so that during its displacement from the raised position, the support edge exerts an increasing reaction which decreases after having reached a maximum value in the intermediate position.
- the value of the axial pressure to be applied on the support edge of the cap to move it from its raised position to its intermediate position is greater than the pressure necessary to ensure engagement of the plug in the neck of the container with a locking of the cap on the neck.
- Such a value of the stiffness of the connecting web makes it possible to guarantee that the support edge does not lower once the plug is perfectly engaged and the cap is locked on the neck of the container.
- only the raised position of the bearing edge is a stable position so that in case of relaxation of the axial force, the bearing edge automatically returns to its raised position.
- the locking means of the cap can be made in different ways and for example include locking fingers forming a one-piece assembly with the cap.
- such an embodiment is not necessary and the locking means can be reported on or in the cap.
- the locking means comprise a ring which is arranged in part at least inside the cap and which comprises an annular ceiling and a peripheral rim, integral with the annular ceiling, from which extends at least two elastically deformable tongues which have, opposite the flange, a locking end intended to engage under the neck of the container.
- a locking ring facilitates the manufacture of the cap, ensuring a good appearance.
- this embodiment makes it possible to perfectly dissociate the phases of depression of the cap and locking of the cap on the neck of the container thus avoiding an accumulation of constraints resulting from the depression of the cap and the locking of the cap .
- each tongue extends opposite the annular ceiling in a substantially axial direction, its locking end being bent inwards to define a foot intended to bear under the neck of the container.
- each tongue has a distal portion, which is oriented outwards, and, at the outer face of this distal portion at the rear of the foot, a locking pin intended to cooperate with a blocking housing complementary to the cap.
- the inner face of the distal portion of each tongue is shaped to come, in the locking position, bearing against the neck of the container.
- each tongue forming the foot is reinforced.
- At least one tongue has, at the level of the outer face of a proximal portion, an assembly rib intended to cooperate with the locking housing in order to bind the ring to the cap before complete engagement. of the headdress on the ring.
- each tongue extends towards the annular ceiling from the peripheral flange being oriented towards the inside of the ring.
- the cap comprises a skirt which has, at an end opposite the cap, means for blocking the movement of the tongue when the cap is complementarily engaged on the ring.
- the ring comprises an outer annular belt intended to surround the skirt of the cap when the cap is completely engaged on the ring.
- the cap comprises locking means intended to cooperate with complementary locking means of the annular belt, when the cap is completely engaged on the ring, so as to prevent withdrawal of the ring. cap.
- the invention also relates to a container equipped with a closure device according to the invention.
- a closure device illustrated in FIG. figure 1 and designated as a whole by the reference 1, is intended to ensure a sealed tight closure of the neck C of a container B.
- the closure device 1 comprises an elastomeric stopper 2 intended to be engaged in the neck C of the container.
- the plug 2 has a general shape in "T” with a tubular body 3 intended to be engaged inside the neck 2.
- the body 3 is then surmounted by a head 4 defining a peripheral wing 5 of support on the edge upper cervix C.
- the closure device also comprises a plastic cap 10 which is able to cover both the neck C and the plug 2 in place in the neck C as shown in FIGS. Figures 5 and 6 .
- the cap 10 comprises locking means 11 on the neck.
- the cap 10 has a peripheral skirt 12 of generally cylindrical general shape of axis ⁇ .
- the cap 10 also comprises a top 13 integral with the skirt 12 and provided with a through axial bore 14.
- the locking means 11 of the cap 10 are made in the form of a ring 11 which is intended to be arranged in part at least inside the cap 10.
- the ring 11 comprises an annular cap 17 provided with a through axial opening 18 located opposite the axial bore 14 of the cap 10, when the ring 11 is engaged inside the latter.
- the ceiling 17 is bordered by a peripheral flange 19 from which extends, at least two and, according to the example illustrated, eight elastically deformable tongues 20.
- each tongue 20 extends from the flange 19 in a substantially axial direction opposite the ceiling 17.
- each tongue 19 is bent inwardly of the ring 11 to define a foot 21 intended to engage under the neck C of the container R as will appear later .
- the foot 21 of each tongue is thickened or reinforced relative to the rest of the tongue so as to have good resistance to tearing.
- a distal portion 22 of each tongue is oriented towards the outside and has at its outer face a locking pin 23 intended to cooperate with a complementary housing 24 for blocking the cap 10 when the latter is fully engaged on the locking ring.
- the complementary housing 24 is in the form of an annular groove arranged inside the skirt 12 of the cap 10 and near a lower end thereof.
- At least one and, according to the illustrated example, four of the tabs have at the outer face of a proximal portion, an assembly rib 25 intended to cooperate with the locking housing, here the groove 24, for connect the ring 11, to the cap 10 before full engagement of the cap 10 on the ring 11 as shown more particularly the figures 1 and 2 . It may be noticed that on the figure 3 only two of the four joining ribs 25 are visible, while on the figures 1 , 2 , 4 to 6 only one of the connecting ribs 25 is visible.
- the closure device 1 further comprises a cap 30 which has a central or axial stud 31 engaged inside the axial bore 14 so as to connect the cap 30 to the cap 10.
- the cap 30 closes the axial bore 14 and prevents, prior to its removal, any access to the plug 2 by the bore 14 and the opening 18.
- the cap 30 further comprises a peripheral support edge 32 which is connected to the stud 31 via at least one and, in the example shown, exactly a connecting web 33 elastically deformable so as to allow axial displacement of the support flange 32 under the effect of an axial force.
- the support flange is movable between a raised position R, illustrated figure 1 , and a lowered position A illustrated figure 6 .
- the web 33 is adapted so that the raised position R is a stable position while the other positions are unstable positions. Thanks to that As a feature, the bearing edge automatically returns to the raised position R when the stress applied to it is released.
- the closure device 1, as thus constituted is implemented in the following manner.
- the stopper 2 is partially engaged in the neck of the container B as shown in FIG. figure 1 and the assembly formed of the locking ring 11, the cap 10 and the cap 30 is positioned on the cap 2, the ceiling 17 of the ring 11 bearing on the head 4 of the cap 2.
- the container B thus equipped is then placed inside a freeze dryer not shown with other identical containers, similarly equipped, so that their content is dehydrated.
- the closure device 1 is, for this purpose, designed so that, in its semi engaged position as illustrated in FIG. figure 1 , it allows communication between the outside environment and the inside of the container B to allow evacuation of the vapors produced during dehydration. Once the latter has been completed, it can be final closure of all containers equipped with closure devices 1 according to the invention and disposed within the freeze dryer.
- the figure 7 illustrates the value of the force exerted on or by the support flange 32 of a closure device 1 as a function of the displacement of said bearing edge 32.
- the depressing phase as described above substantially corresponds to the first part I of the curve.
- the force on the support edge 32 is maintained, as shown in the second portion II of the curve, so as to ensure the engagement of the cap 10 on the locking ring 11.
- the connecting ribs 25 are disengaged from the annular groove 24, zone IIa of the curve, then the locking ends 21 of the tongues 20 tilting. under the C-neck as shown in the figure 5 , which corresponds to zone IIb of the curve.
- the depression of the cap 10 is continued until the locking lugs 23 are brought into the groove 24 as illustrated in FIG. figure 5 and which corresponds to zone IIc of the curve.
- the closure device 1 according to the invention is perfectly locked on the container B so that it ensures a secure sealing.
- the stress exerted on the pressure plate will refer mainly to the web 33 to the extent that there is a continuity of support between the neck C and the top 13.
- the force exerted will induce a displacement of the bearing edge 32 from the raised position R to an intermediate position I.
- the latter will exert during the displacement a high resistance to the collapse of the support edge 32 , as shown in part IIIa of the curve.
- the web 33 will be designed in such a way that the force necessary to bring the support flange 32 from the raised position R to the intermediate position I is greater than the effort it is necessary to exercise to ensure a complete depression of the plug 2 accompanied by a locking of the ring 11 and the cap 10.
- the bearing flange 32 is in the raised position R, in the phase corresponding to the portion IIIa of the curve, the bearing flange 32 moves from the raised position R to the intermediate position I, then in the phase corresponding to the Part IIIb of the curve the support flange 32 moves from the intermediate position I to the lowered position A.
- the last part IIIc of the curve corresponds to a case where the force on the support edge 32 is maintained, the displacement of the plate corresponding to an elastic compression of the bearing edge 32 and of the various constituent elements of the closure device 1.
- the peripheral rim 34 of the cap 30 has at least one and, according to the illustrated example, four vents 35, two of which are visible at the figure 3 .
- peripheral rim 34 comprises a series of pins or asperities 36 distributed around its periphery in order to facilitate the gripping of the cap 30 for its tearing in order to allow the contents of the container B to be removed by means of, for example, a syringe whose needle is inserted into the head 4 of the stopper 2
- the skirt 10 comprises an intermediate groove 41 inside which are positioned the assembly ribs 25 once the cap 10 is fully engaged on the locking ring 11 as shown in FIG. figure 5 .
- each tongue 20 is, in the locked position substantially bearing against the neck C of the container B, while the outer face of each tongue has, in axial section, a general V-shaped conformation.
- Such an arrangement induces a bracing of each tongue 20 when a tearing stress is exerted on the cap 10 or the foot 21 of the tongues 20, the closure device according to the invention being moreover locked on the neck C of the container B.
- the cap 10 and the associated locking means can be made in a completely different manner than that described above with reference to the Figures 1 to 6 .
- the figure 8 illustrates another embodiment of a closure device 1 in which the tabs 20 extend upwards towards the annular ceiling 13 from the peripheral rim 19.
- the ring 11 further comprises an outer annular belt 45 which defines, with the flange 19, an annular housing 46 within which the skirt 12 of the cap 10 engages.
- the lower end of the skirt 12 opposite to the cap 30 has a conformation which defines locking means the movement of the tongues 20 when the cap is fully engaged on the ring 10.
- the skirt 12 of the cap 10 has locking means made in the form of a peripheral lip 47 intended to cooperate with complementary locking means of the belt 46, in this case an annular groove 48. The locking means 47 and 48 prevent inadvertent removal of the cap 10 when the latter has been engaged on the locking ring 11.
- the support edge 32 and the connecting web 33 have a monostable character, the support edge automatically finding the raised position R when no stress is applied to it.
- the connecting web 33 could be designed so that the support edge 2 has a bistable character. Thus, when the bearing edge exceeds the intermediate position I, it spontaneously join the lowered position A. Thus, only the raised and lowered positions A of the support edge 32 are stable positions.
Landscapes
- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Closures For Containers (AREA)
Description
L'invention concerne un dispositif de bouchage pour un récipient pourvu d'un col, ainsi qu'un récipient équipé d'un tel dispositif.The invention relates to a closure device for a container provided with a neck, and a container equipped with such a device.
Dans le domaine des récipients pour médicaments, il est connu d'utiliser un flacon en verre pour conserver un principe actif sous forme de lyophilisat de poudre ou de solution liquide. Un tel flacon, comme mentionné dans
Lors de la mise en oeuvre d'un tel dispositif de bouchage pour des produits pharmaceutiques lyophilisés, par exemple, chaque récipient est rempli d'une quantité de produit à lyophiliser puis le bouchon est disposé sur le col du récipient de manière à en être solidaire tout en préservant une communication entre le milieu extérieur et l'intérieur du récipient. Les récipients ainsi remplis et prébouchés sont disposés en lots sur les étagères d'un lyophilisateur à l'intérieur duquel les produits seront déshydratés. Lors de la lyophilisation du contenu d'un récipient, on procède à un séchage à froid sous vide qui assure l'extraction de l'eau du produit par sublimation et évaporation.During the implementation of such a closure device for freeze-dried pharmaceutical products, for example, each container is filled with a quantity of product to be freeze-dried and the stopper is placed on the neck of the container so as to be secured to it. while preserving communication between the outside environment and the interior of the container. The containers thus filled and prebunched are arranged in batches on the shelves of a lyophilizer inside which the products will be dehydrated. During the freeze-drying of the contents of a container, a vacuum drying is carried out which ensures the extraction of water from the product by sublimation and evaporation.
Une fois la déshydratation des produits assurée, il est appliqué, à l'intérieur du lyophilisateur et à l'ensemble des bouchons des récipients, une pression de manière à assurer un bouchage hermétique des récipients par engagement de chaque bouchon sur ou dans le col du récipient correspondant. Ce bouchage par lot est généralement effectué avec le seul bouchon en élastomère sans la coiffe de verrouillage. Ainsi, il est nécessaire de reprendre, en sortie du lyophilisateur, chacun des récipients pour y mettre en place la coiffe de verrouillage. Afin d'éviter une telle opération de reprise, il a été envisagé de disposer, sur chacun des bouchons des récipients prébouchés et avant lyophilisation, la coiffe de verrouillage correspondante de manière que, lors du bouchage par pressage effectué à l'intérieur du lyophilisateur, la coiffe de verrouillage soit également mise en place. Cependant, cette opération n'a pas donné pleinement satisfaction avec les dispositifs de bouchage selon l'art antérieur.Once dehydration of the products ensured, it is applied, inside the lyophilizer and all the caps of the containers, a pressure so as to ensure hermetic sealing of the containers by engagement of each plug on or in the neck of the container. corresponding container. This batch capping is usually done with the single elastomeric stopper without the locking cap. Thus, it is necessary to take, at the outlet of the lyophilizer, each of the containers to put in place the locking cap. In order to avoid such a recovery operation, it was envisaged that, on each of the plugs of the pre-filled containers and before lyophilization, the corresponding locking cap so that, during the capping by pressing carried out inside the lyophilizer, the locking cap is also put in place. However, this operation did not give full satisfaction with the closure devices according to the prior art.
En effet, lorsque la coiffe doit être déplacée pour être verrouillée autour du col du récipient correspondant, il se produit des frottements dont l'intensité varie en fonction, d'une part, des tolérances de fabrication des pièces constitutives de la coiffe et, d'autre part, du pré-positionnement de ces pièces lorsqu'elles sont installées sur le col du récipient. Ainsi, lorsqu'on utilise un plateau presseur à l'intérieur du lyophilisateur pour verrouiller les coiffes d'un grand nombre de récipients, il arrive que, compte tenu des tolérances de fabrication des pièces constitutives de ces coiffes et des jeux de fonctionnement du plateau presseur, certaines coiffes ne soient pas verrouillées correctement. De même, les variations dimensionnelles des récipients eux-mêmes et des bouchons utilisés ont une influence négative sur la fermeture d'un lot de récipients. Compte tenu de ces difficultés, on a jusqu'à présent renoncé à mettre en place simultanément les bouchons et la coiffe de verrouillage de récipients par lots à l'intérieur d'un lyophilisateur, ce qui impose une mise en place ultérieure de la coiffe et donc des manipulations complexes et onéreuses lors du conditionnement de produits lyophilisés.Indeed, when the cap has to be moved to be locked around the neck of the corresponding container, friction occurs whose intensity varies according to, on the one hand, the manufacturing tolerances of the parts constituting the cap and, d on the other hand, the pre-positioning of these parts when they are installed on the neck of the container. Thus, when using a pressure plate inside the lyophilizer to lock the caps of a large number of containers, it happens that, given the manufacturing tolerances of the constituent parts of these caps and the games of operation of the tray pressure, some caps are not locked properly. Similarly, the dimensional variations of the containers themselves and the plugs used have a negative influence on the closure of a batch of containers. In view of these difficulties, it has so far been decided not to set up simultaneously the stoppers and the cap for locking containers in batches inside a lyophilizer, which imposes a subsequent installation of the cap and therefore complex and expensive handling during the packaging of freeze-dried products.
C'est à ces inconvénients qu'entend plus particulièrement remédier l'invention en proposant un dispositif de bouchage grâce auquel un effort de verrouillage d'une coiffe peut être efficacement transmis, y compris en tenant compte des tolérances de fabrication des flacons, des bouchons, des pièces constitutives d'une coiffe et des organes mécaniques d'application d'un effort.It is to these drawbacks that the invention more particularly intends to remedy by proposing a closure device by means of which a locking force of a cap can be efficiently transmitted, including taking into account the manufacturing tolerances of the bottles, the plugs. , constituent parts of a cap and mechanical organs for applying a force.
A cet effet, l'invention concerne un dispositif de bouchage pour un récipient avec un col d'axe Δ, ce dispositif comprenant :
- un bouchon en élastomère ;
- une coiffe en matière plastique qui est apte à recouvrir à la fois le col et le bouchon en place dans le col et qui comprend des moyens de verrouillage sur le col ;
- un chapeau adapté sur le dessus de la coiffe par l'intermédiaire d'un plot central et pourvu d'un bord d'appui périphérique relié au plot par au moins un voile de liaison.
- an elastomeric stopper;
- a plastic cap which is capable of covering both the neck and the plug in place in the neck and which comprises locking means on the neck;
- a cap adapted on the top of the cap by means of a central stud and provided with a peripheral support edge connected to the stud by at least one connecting web.
Selon l'invention, le dispositif de bouchage est caractérisé en ce que le voile de liaison, d'une part, est élastiquement déformable de manière à permettre, sous l'effet d'un effort axial, un déplacement axial du bord d'appui à partir d'une position relevée R vers une position abaissée A en passant par une position intermédiaire I, d'autre part, et possède sur une première plage de déformation, correspondant à un déplacement du bord d'appui entre la position relevée R et la position intermédiaire I, une raideur K1 supérieure à la raideur K2 du voile sur une deuxième plage de déformation correspondant à un déplacement du rebord d'appui entre la position intermédiaire I est la position abaissée A.According to the invention, the closure device is characterized in that the connecting web, on the one hand, is elastically deformable so as to allow, under the effect of an axial force, an axial displacement of the support edge from a raised position R to a lowered position A through an intermediate position I, on the other hand, and has on a first range of deformation, corresponding to a displacement of the support edge between the raised position R and the intermediate position I, a stiffness K 1 greater than the stiffness K 2 of the web on a second range of deformation corresponding to a displacement of the support flange between the intermediate position I is the lowered position A.
La mise en oeuvre d'un tel voile de liaison présente l'avantage de permettre, lorsque le bouchon et la coiffe ont été complètement engagés et verrouillés, un affaissement du bord d'appui, de sorte que ce dernier n'exerce plus qu'une faible contrainte ou réaction sur le plateau presseur dont l'action se reporte alors sur les bords d'appui des dispositifs de bouchage n'étant pas encore verrouillés. Ce report permet donc d'augmenter l'effort disponible sur les dispositifs de bouchage non encore engagés et donc de compenser les variations liées aux dispersions dimensionnelles et structurelles. Ainsi, l'invention permet d'augmenter substantiellement le nombre de récipients convenablement bouchés en sortie du lyophilisateur.The implementation of such a connecting web has the advantage of allowing, when the cap and the cap have been fully engaged and locked, a subsidence of the support edge, so that it no longer exerts that a low stress or reaction on the pressure plate whose action then refers to the bearing edges of the closure devices not yet locked. This report therefore makes it possible to increase the available force on the clogging devices not yet engaged and thus to compensate for the variations related to dimensional and structural dispersions. Thus, the invention makes it possible to substantially increase the number of containers properly sealed at the outlet of the lyophilizer.
Selon une caractéristique de l'invention, le voile de liaison est adapté pour que lors de son déplacement à partir de la position relevée, le bord d'appui exerce une réaction croissante qui décroît après avoir atteint une valeur maximale en position intermédiaire.According to one characteristic of the invention, the connecting web is adapted so that during its displacement from the raised position, the support edge exerts an increasing reaction which decreases after having reached a maximum value in the intermediate position.
Selon une autre caractéristique de l'invention, la valeur de la pression axiale à appliquer sur le bord d'appui du chapeau pour le faire passer de sa position relevée à sa position intermédiaire est supérieure à la pression nécessaire pour assurer un engagement du bouchon dans le col du récipient avec un verrouillage de la coiffe sur le col. Une telle valeur de la raideur du voile de liaison permet de garantir que le bord d'appui ne s'abaisse qu'une fois le bouchon parfaitement engagé et la coiffe verrouillée sur le col du récipient.According to another characteristic of the invention, the value of the axial pressure to be applied on the support edge of the cap to move it from its raised position to its intermediate position is greater than the pressure necessary to ensure engagement of the plug in the neck of the container with a locking of the cap on the neck. Such a value of the stiffness of the connecting web makes it possible to guarantee that the support edge does not lower once the plug is perfectly engaged and the cap is locked on the neck of the container.
Selon encore une autre caractéristique de l'invention, seule la position relevée du bord d'appui est une position stable de sorte qu'en cas de relâchement de l'effort axial, le bord d'appui retourne automatiquement à sa position relevée.According to yet another feature of the invention, only the raised position of the bearing edge is a stable position so that in case of relaxation of the axial force, the bearing edge automatically returns to its raised position.
Selon l'invention, les moyens de verrouillage de la coiffe peuvent être réalisés de différentes manières et par exemple comprendre des doigts de verrouillage formant un ensemble monobloc avec la coiffe. Toutefois, selon l'invention, un tel mode de réalisation n'est pas nécessaire et les moyens de verrouillage peuvent être rapportés sur ou dans la coiffe.According to the invention, the locking means of the cap can be made in different ways and for example include locking fingers forming a one-piece assembly with the cap. However, according to the invention, such an embodiment is not necessary and the locking means can be reported on or in the cap.
Ainsi, selon une forme de réalisation, les moyens de verrouillage comprennent une bague qui est disposée en partie au moins à l'intérieur de la coiffe et qui comprend un plafond annulaire et un rebord périphérique, solidaire du plafond annulaire, à partir duquel s'étend au moins deux languettes élastiquement déformables qui possèdent, à l'opposé du rebord, une extrémité de verrouillage destinée à venir s'engager sous le col du récipient. La mise en oeuvre d'une telle bague de verrouillage permet de faciliter la fabrication de la coiffe, en lui assurant un bon aspect extérieur. De plus, dans certaines configurations, cette réalisation permet de parfaitement dissocier les phases d'enfoncement du bouchon et de verrouillage de la coiffe sur le col du récipient évitant ainsi un cumul des contraintes résultant de l'enfoncement du bouchon et du verrouillage de la coiffe.Thus, according to one embodiment, the locking means comprise a ring which is arranged in part at least inside the cap and which comprises an annular ceiling and a peripheral rim, integral with the annular ceiling, from which extends at least two elastically deformable tongues which have, opposite the flange, a locking end intended to engage under the neck of the container. The implementation of such a locking ring facilitates the manufacture of the cap, ensuring a good appearance. In addition, in certain configurations, this embodiment makes it possible to perfectly dissociate the phases of depression of the cap and locking of the cap on the neck of the container thus avoiding an accumulation of constraints resulting from the depression of the cap and the locking of the cap .
Selon une première variante de cette forme de réalisation, chaque languette s'étend à l'opposé du plafond annulaire selon une direction sensiblement axiale, son extrémité de verrouillage étant recourbée vers l'intérieur pour définir un pied destiné à venir en appui sous le col du récipient.According to a first variant of this embodiment, each tongue extends opposite the annular ceiling in a substantially axial direction, its locking end being bent inwards to define a foot intended to bear under the neck of the container.
Selon une caractéristique de cette première variante, chaque languette possède une portion distale, qui est orientée vers l'extérieur, et, au niveau de la face extérieure de cette portion distale à l'arrière du pied, un ergot de blocage destiné à coopérer avec un logement de blocage complémentaire de la coiffe.According to a feature of this first variant, each tongue has a distal portion, which is oriented outwards, and, at the outer face of this distal portion at the rear of the foot, a locking pin intended to cooperate with a blocking housing complementary to the cap.
Selon une autre caractéristique de cette première variante, la face interne de la partie distale de chaque languette est conformée pour venir, en position de verrouillage, en appui contre le col du récipient.According to another characteristic of this first variant, the inner face of the distal portion of each tongue is shaped to come, in the locking position, bearing against the neck of the container.
Selon encore une autre caractéristique de cette première variante, l'extrémité inférieure de chaque languette formant le pied est renforcée.According to yet another characteristic of this first variant, the lower end of each tongue forming the foot is reinforced.
Selon une autre caractéristique de cette première variante, une languette au moins possède, au niveau de la face extérieure d'une portion proximale, une nervure d'assemblage destinée à coopérer avec le logement de blocage pour lier la bague à la coiffe avant engagement complet de la coiffe sur la bague.According to another characteristic of this first variant, at least one tongue has, at the level of the outer face of a proximal portion, an assembly rib intended to cooperate with the locking housing in order to bind the ring to the cap before complete engagement. of the headdress on the ring.
Selon une deuxième variante de ladite forme de réalisation, chaque languette s'étend en direction du plafond annulaire à partir du rebord périphérique en étant orienté vers l'intérieur de la bague.According to a second variant of said embodiment, each tongue extends towards the annular ceiling from the peripheral flange being oriented towards the inside of the ring.
Selon une caractéristique de cette deuxième variante de réalisation, la coiffe comprend une jupe qui présente au niveau d'une extrémité opposée au chapeau des moyens de blocage du mouvement de la languette lorsque la coiffe est complément engagée sur la bague.According to a feature of this second embodiment, the cap comprises a skirt which has, at an end opposite the cap, means for blocking the movement of the tongue when the cap is complementarily engaged on the ring.
Selon une autre caractéristique de la deuxième variante, la bague comprend une ceinture annulaire extérieure destinée à entourer la jupe de la coiffe lorsque la coiffe est complètement engagée sur la bague.According to another characteristic of the second variant, the ring comprises an outer annular belt intended to surround the skirt of the cap when the cap is completely engaged on the ring.
Selon encore une autre caractéristique de la deuxième variante, coiffe comprend des moyens de verrouillage destinés à coopérer avec des moyens de verrouillage complémentaires de la ceinture annulaire, lorsque la coiffe est complètement engagée sur la bague, de manière à faire obstacle à un retrait de la coiffe.According to yet another characteristic of the second variant, the cap comprises locking means intended to cooperate with complementary locking means of the annular belt, when the cap is completely engaged on the ring, so as to prevent withdrawal of the ring. cap.
L'invention concerne également un récipient équipé d'un dispositif de bouchage selon l'invention.The invention also relates to a container equipped with a closure device according to the invention.
Bien entendu, les diverses formes, variantes et caractéristiques de l'invention peuvent être combinées les unes avec les autres selon différentes combinaisons dans la mesure où elles ne sont pas incompatibles ou exclusives les unes des autres.Of course, the various forms, variants and features of the invention can be combined with each other in different combinations to the extent that they are not incompatible or exclusive of each other.
Par ailleurs, diverses autres caractéristiques de l'invention ressortent de la description ci-dessous effectuée en relation avec les dessins qui illustrent des formes non limitatives de réalisation d'un dispositif de bouchage selon l'invention.
- La
figure 1 est une coupe axiale d'un dispositif de bouchage selon l'invention, pré-positionné sur le col d'un récipient avant enfoncement complet du bouchon et verrouillage de la coiffe, le chapeau étant en position relevée. - La
figure 2 est une coupe axiale de la coiffe du dispositif de bouchage illustré à lafigure 1 . - La
figure 3 est une perspective éclatée de la coiffe illustrée à lafigure 1 . - Les
figures 4 à 6 sont des coupes axiales analogues à lafigure 1 montrant des étapes successives de la mise en place du dispositif de bouchage. A lafigure 4 , le chapeau est en position relevée, tandis qu'à lafigure 5 il est en position intermédiaire, et à lafigure 6 en position abaissée. - La
figure 7 est un graphique de la valeur de l'effort axial exercé sur ou par le rebord d'appui pendant l'enfoncement du bouchon suivi du verrouillage de la coiffe, avec en abscisses le déplacement du rebord d'appui exprimé en mm et en ordonnées la valeur absolue de l'effort axial exprimé en Newton. - La
figure 8 est une perspective partiellement arrachée montrant une variante de réalisation du dispositif de bouchage selon l'invention.
- The
figure 1 is an axial section of a closure device according to the invention, pre-positioned on the neck of a container before complete depression of the cap and locking of the cap, the cap being in the raised position. - The
figure 2 is an axial section of the cap of the closure device illustrated in FIG.figure 1 . - The
figure 3 is an exploded perspective of the cap illustrated in thefigure 1 . - The
Figures 4 to 6 are axial sections similar to thefigure 1 showing successive stages of the installation of the closure device. To thefigure 4 the hat is in the raised position, while at thefigure 5 he is in the middle position, and at thefigure 6 in the lowered position. - The
figure 7 is a graph of the value of the axial force exerted on or by the support flange during the depression of the plug followed by locking of the cap, with the abscissa displacement of the support flange expressed in mm and ordinate the absolute value of the axial force expressed in Newton. - The
figure 8 is a partially cutaway perspective showing an alternative embodiment of the closure device according to the invention.
Un dispositif de bouchage, selon l'invention, illustré à la
Le dispositif de bouchage comprend également une coiffe en matière plastique 10 qui est apte à recouvrir à la fois le col C et le bouchon 2 en place dans le col C comme le montre les
Selon l'exemple illustré, les moyens de verrouillage 11 de la coiffe 10 sont réalisés sous la forme d'une bague 11 qui est destinée à être disposée en partie au moins à l'intérieur de la coiffe 10. Comme cela ressort notamment des
Le dispositif de bouchage 1 selon l'invention comprend en outre un chapeau 30 qui présente un plot central ou axial 31 engagé à l'intérieur de l'alésage axial 14 de manière à lier le chapeau 30 à la coiffe 10. Ainsi, le chapeau 30 obture l'alésage axial 14 et fait obstacle, avant son retrait, à tout accès au bouchon 2 par l'alésage 14 et l'ouverture 18. Le chapeau 30 comprend en outre, un bord d'appui périphérique 32 qui est relié au plot 31 par l'intermédiaire d'au moins un et, selon l'exemple illustré, exactement un voile de liaison 33 élastiquement déformable de manière à permettre un déplacement axial du rebord d'appui 32 sous l'effet d'un effort axial. Ainsi, le rebord d'appui est mobile entre une position relevée R, illustrée
Le dispositif de bouchage 1, tel qu'ainsi constitué est mis en oeuvre de la manière suivante.The closure device 1, as thus constituted is implemented in the following manner.
Une fois le remplissage du récipient effectué, au moyen d'un produit devant par exemple lyophilisé, le bouchon 2 est partiellement engagé dans le col du récipient B comme le montre la
Pour ce faire, il est appliqué sur le bord d'appui 32 et au moyen d'un plateau presseur P schématisé en traits mixtes aux
La
Une fois l'enfoncement du bouchon 2 assuré, l'effort sur le bord d'appui 32 est maintenue, comme le montre la deuxième portion II de la courbe, de manière à assurer l'engagement de la coiffe 10 sur la bague de verrouillage 11. Tout d'abord, les nervures d'assemblage 25 se dégagent de la gorge annulaire 24, zone IIa de la courbe, puis les extrémités de verrouillage 21 des languettes 20 se rabattant sous le col C comme le montre la
Ainsi, pendant les phases de bouchage correspondant aux parties I et II de la courbe de la
Lorsque l'effort sur le bord d'appui 32 est interrompu et le plateau presseur retiré, le bord d'appui 32 rejoint spontanément sa position relevée R sous l'effet de l'élasticité du voile 33. Pour éviter un effet ventouse qui empêcherait le bord d'appui 32 et le voile de liaison 33 de retrouver leur configuration d'origine, le rebord périphérique 34 du chapeau 30 présente au moins un et, selon l'exemple illustré, quatre évents 35 dont deux sont visibles à la
De plus, le rebord périphérique 34 comprend une série de picots ou aspérités 36 répartis sur son pourtour afin de faciliter la préhension du chapeau 30 pour son arrachage en vue de permettre un prélèvement du contenu du récipient B au moyen, par exemple, d'une seringue dont l'aiguille est enfoncée dans la tête 4 du bouchon 2In addition, the
Selon l'exemple illustré, afin d'éviter tout conflit entre la jupe 10 et les nervures d'assemblage 25 en position de verrouillage telle qu'illustré à la
Par ailleurs, il pourra être remarqué que, selon l'exemple illustré, la face intérieure de la portion distale 22 de chaque languette 20 est, en position verrouillée sensiblement en appui contre le col C du récipient B, tandis que la face extérieure de chaque languette présente, en section axiale, une conformation générale en V. Un tel agencement induit un arc-boutement de chaque languette 20 lorsqu'une contrainte d'arrachage est exercée sur la coiffe 10 ou le pied 21 des languettes 20, le dispositif de bouchage selon l'invention étant par ailleurs verrouillé sur le col C du récipient B.Furthermore, it may be noted that, according to the illustrated example, the inner face of the
Bien entendu, selon l'invention, la coiffe 10 et les moyens de verrouillage associés peuvent être réalisés d'une toute autre manière que celle décrite précédemment en référence aux
Ainsi, la
Par ailleurs, selon les exemples décrits précédemment, le bord d'appui 32 et le voile de liaison 33 présentent un caractère monostable, le bord d'appui retrouvant automatiquement la position relevée R lorsque aucune contrainte ne lui est appliquée. Toutefois, selon l'invention le voile de liaison 33 pourrait être conçu pour que le bord d'appui 2 possède un caractère bistable. Ainsi, lorsque le bord d'appui dépasserait la position intermédiaire I, il rejoindrait spontanément la position abaissée A. Ainsi, seules les positions relevée R et abaissée A du bord d'appui 32 sont des positions stables.Furthermore, according to the examples described above, the
Bien entendu, diverses autres modifications peuvent être apportées à l'invention dans le cadre des revendications.Of course, various other modifications may be made to the invention within the scope of the claims.
Claims (16)
- A stopper device for stopping a container (B) having a neck (C) of axis Δ, said device comprising:• an elastomer stopper (2);• a a cover (10) made of a plastics material that is suitable for covering both the neck (C) and the stopper (2) in place in the neck (C), and that is provided with locking means (11) for locking it to the neck (C); and• a cap (30) that fits over the top of the cover (10) by means of a central stud (31) and that is provided with a peripheral press rim (32) connected to the central stud via at least one connecting web, characterized in that firstly the connecting web is elastically deformable in a manner such that, under the effect of an axial force, it enables the press rim to be moved axially from a raised position (R) towards a lowered position (A) via an intermediate position (I), and secondly, over a first deformation range, corresponding to the press rim being moved from the raised position (R) to the intermediate position (I), said connecting web has a stiffness K1 greater than the stiffness K2 of the web over a second deformation range corresponding to the press rim being moved from the intermediate position (I) to the lowered position (A).
- A device according to claim 1, characterized in that the connecting web (33) is adapted so that, while the press rim (32) is moving from the raised position (R), said press rim exerts an increasing reaction that decreases after it has reached a maximum value at the intermediate position.
- A device according to claim 1 or claim 2, characterized in that the value of the axial force to be applied to the press rim (32) of the cap (30) in order to cause it to go from its raised position (R) to its intermediate position (I) is greater than the force necessary for engaging the stopper (2) into the neck (C) of the container (B) with the cover (10) being locked to the neck.
- A device according to any one of claims 1 to 3, characterized in that only the raised position (R) of the press rim (32) is a stable position so that, in the event that the axial force ceases to be applied, the press rim (32) returns automatically to its raised position.
- A device according to any one of claims 1 to 3, characterized in that only the raised position (R) and the lowered position (A) are stable positions.
- A device according to any one of claims 1 to 5, characterized in that the locking means comprise a ring (11) that is placed at least in part inside the cover (10) and that has an annular ceiling (17) and a peripheral band (19) that is integral with the annular ceiling (17) and from which there extend at least two elastically deformable tongues (20) that, opposite from the band (19), have respective locking ends designed to engage under the neck (C) of the container (B).
- A device according to claim 6, characterized in that each tongue (20) extends away from the annular ceiling (17) in a direction that is substantially axial, its locking end (21) being curved over inwards to define a catch designed to come into abutment under the neck (C) of the container (B).
- A device according to claim 7, characterized in that each tongue (20) has a distal portion (22) that extends outwards and, on the outside face of said distal portion, each tongue has a blocking lug (23) that is designed to co-operate with a complementary blocking recess (24) in the cover (10).
- A device according to claim 8, characterized in that the inside face of the distal portion (22) of each tongue (20) is shaped to come into abutment against the neck (C) of the container (B) in the locking position.
- A device according to any one of claims 7 to 9, characterized in that the bottom end of each tongue that forms its catch is reinforced.
- A device according to any one of claims 8 to 10, characterized in that at least one of the tongues (20) has, on the outside face of a proximal portion, an assembly rib (25) designed to co-operate with the blocking recess to couple the ring to the cover (10) before the cover (10) is engaged fully over the ring.
- A device according to claim 6, characterized in that each tongue (20) extends towards the annular ceiling (17) from the peripheral rim (19) while extending towards the inside of the ring (11).
- A device according to claim 12, characterized in that the cover (10) has a skirt (12) that, at an end opposite from the cap (32), is provided with blocking means for blocking movement of the tongues (20) when the cover (10) is fully engaged over the ring (11).
- A device according to claim 13, characterized in that the ring has an outer annular belt (45) designed to surround the skirt (12) of the cover (10) when the cover (10) is fully engaged over the ring (11).
- A device according to claim 14, characterized in that the cover (10) is provided with locking means (47) designed to co-operate with complementary locking means (48) of the annular belt (45) when the cover (10) is fully engaged over the ring (11) in such a manner as to oppose removal of the cover (10).
- A container equipped with a stopper device (1) according to any one of claims 1 to 15.
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PL09710963T PL2242701T3 (en) | 2008-02-11 | 2009-02-10 | Stopper device comprising a supporting cap, and container provided with such a device |
CY20121100729T CY1113066T1 (en) | 2008-02-11 | 2012-08-13 | CLOSURE LOCKING WITH SUPPORT LID AND CONTAINER EQUIPPED |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0850837A FR2927316B1 (en) | 2008-02-11 | 2008-02-11 | CLAMPING DEVICE HAVING A SUPPORT HAT AND CONTAINER EQUIPPED WITH SUCH A DEVICE |
PCT/FR2009/050209 WO2009101354A1 (en) | 2008-02-11 | 2009-02-10 | Stopper device comprising a supporting cap, and container provided with such a device |
Publications (2)
Publication Number | Publication Date |
---|---|
EP2242701A1 EP2242701A1 (en) | 2010-10-27 |
EP2242701B1 true EP2242701B1 (en) | 2012-06-20 |
Family
ID=39766879
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP09710963A Active EP2242701B1 (en) | 2008-02-11 | 2009-02-10 | Stopper device comprising a supporting cap, and container provided with such a device |
Country Status (12)
Country | Link |
---|---|
US (1) | US8777031B2 (en) |
EP (1) | EP2242701B1 (en) |
JP (1) | JP5364869B2 (en) |
CN (1) | CN101952179B (en) |
AU (1) | AU2009213918A1 (en) |
CA (1) | CA2714618A1 (en) |
CY (1) | CY1113066T1 (en) |
ES (1) | ES2387600T3 (en) |
FR (1) | FR2927316B1 (en) |
MX (1) | MX2010008842A (en) |
PL (1) | PL2242701T3 (en) |
WO (1) | WO2009101354A1 (en) |
Families Citing this family (59)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2950035B1 (en) * | 2009-09-15 | 2011-09-02 | Raymond A & Cie | LOCKING COIFFE FOR CONTAINER WITH COLLAR |
FR2967655B1 (en) | 2010-11-24 | 2014-03-14 | Biocorp Rech Et Dev | DEVICE FOR CLOSING A CONTAINER, CONTAINER EQUIPPED WITH SUCH A DEVICE AND METHOD FOR CLOSING A BATCH OF SUCH CONTAINERS |
FR2967656B1 (en) * | 2010-11-24 | 2012-12-07 | Biocorp Rech Et Dev | DEVICE FOR CLOSING A CONTAINER AND CONTAINER EQUIPPED WITH SUCH A DEVICE |
FR2968517B1 (en) * | 2010-12-09 | 2013-11-01 | Oreal | DEVICE FOR PACKAGING A COSMETIC PRODUCT |
CN102730290A (en) * | 2011-03-31 | 2012-10-17 | 陈玉祥 | Sealed bottle cap |
EP2511190A1 (en) * | 2011-04-14 | 2012-10-17 | Becton Dickinson France | Sealing device for a container |
ITMI20110789A1 (en) * | 2011-05-09 | 2012-11-10 | Ibsa Inst Biochimique Sa | GROUP FOR SEALING BOTTLES CONTAINING INJECTABLE STERILE DRUGS OR SIMILAR SUBSTANCES, SUITABLE FOR USE IN PRODUCTION LINES OF HIGH-SPEED BOTTLES, RESPECTIVE SEALING CAP, AND CORRESPONDING SEALED BOTTLE |
FR2975976B1 (en) * | 2011-06-06 | 2014-08-29 | Biocorp Rech Et Dev | CLOSURE DEVICE AND CONTAINER EQUIPPED WITH SUCH A DEVICE |
FR2976265B1 (en) | 2011-06-08 | 2014-08-29 | Biocorp Rech Et Dev | CLOSURE DEVICE AND CONTAINER EQUIPPED WITH SUCH A DEVICE |
GB2485254C (en) * | 2011-08-22 | 2013-12-25 | Eulysis Uk Ltd | A container having a recessed closure for drying and storing one or more active agents |
CN104093642A (en) * | 2011-12-16 | 2014-10-08 | Cpa公司 | Device for capping a bottle |
US11027591B2 (en) * | 2012-09-13 | 2021-06-08 | Airsept, Inc. | Service port cap with click lock |
US9051074B2 (en) * | 2012-10-11 | 2015-06-09 | Owens-Brockway Glass Container Inc. | Container, closure, and package |
EP2826458A1 (en) | 2013-07-17 | 2015-01-21 | F.Hoffmann-La Roche Ag | Closure for a vial |
WO2015029580A1 (en) * | 2013-09-02 | 2015-03-05 | 大成化工株式会社 | Cap for vial |
ITMI20132005A1 (en) * | 2013-12-02 | 2015-06-03 | Antonio Mutterle | CLOSING SYSTEM FOR BOTTLE, RELATIVE BOTTLE AND ASSEMBLY METHOD |
CN103754473A (en) * | 2014-01-10 | 2014-04-30 | 陈耀民 | Combination cover for medicine |
DK3157833T3 (en) | 2014-06-18 | 2018-11-19 | Altergon Sa | Method of tightly closing a bottle and correspondingly tightly closed bottle |
JP6882197B2 (en) | 2015-06-29 | 2021-06-02 | アントニオ ミュッターレMUTTERLE, Antonio | Sealed assembly for bottles, related bottles and assembly methods |
US10093460B2 (en) | 2015-08-14 | 2018-10-09 | Yeti Coolers, Llc | Container with magnetic cap |
USD787893S1 (en) | 2015-11-20 | 2017-05-30 | Yeti Coolers, Llc | Jug |
RU2724313C2 (en) * | 2015-12-13 | 2020-06-22 | Содастрим Индастриз Лтд. | Gear clamp of a gassing machine with a built-in pneumatic blocking device |
FR3047188B1 (en) * | 2016-01-29 | 2018-01-12 | Constellium Issoire | TOOLING FOR THE PRODUCTION OF A METAL PRODUCT BY CASTING IN LOAD |
NL2016212B1 (en) * | 2016-02-03 | 2017-08-11 | Scholle Ipn Ip Bv | A closure assembly and container provided with said closure assembly. |
US10358284B2 (en) | 2016-06-16 | 2019-07-23 | Sigma Phase, Corp. | System for providing a single serving of a frozen confection |
US10426180B1 (en) | 2016-06-16 | 2019-10-01 | Sigma Phase, Corp. | System for providing a single serving of a frozen confection |
EP3632274B1 (en) | 2016-10-17 | 2021-05-12 | Yeti Coolers, LLC | Container and method of forming a container |
US10959552B2 (en) | 2016-10-17 | 2021-03-30 | Yeti Coolers, Llc | Container and method of forming a container |
US11034505B2 (en) | 2016-10-17 | 2021-06-15 | Yeti Coolers, Llc | Container and method of forming a container |
US10959553B2 (en) | 2016-10-17 | 2021-03-30 | Yeti Coolers, Llc | Container and method of forming a container |
CA2955469A1 (en) * | 2017-01-20 | 2018-07-20 | Robert Kamen | Biohazardous material transporting pig |
USD860716S1 (en) | 2017-03-27 | 2019-09-24 | Yeti Coolers, Llc | Container lid |
CN107619768A (en) * | 2017-09-26 | 2018-01-23 | 遵义市永胜金属设备有限公司 | One kind connects fat |
JP6848126B2 (en) * | 2018-01-19 | 2021-03-24 | ウェスト ファーマスーティカル サービシーズ ドイチェラント ゲーエムベーハー ウント カンパニー カーゲー | Blocking device |
US11469007B2 (en) | 2018-03-09 | 2022-10-11 | Robert Kamen | Compression member for biohazardous material transporting pig |
US10612835B2 (en) | 2018-08-17 | 2020-04-07 | Sigma Phase, Corp. | Rapidly cooling food and drinks |
US10543978B1 (en) | 2018-08-17 | 2020-01-28 | Sigma Phase, Corp. | Rapidly cooling food and drinks |
US11470855B2 (en) | 2018-08-17 | 2022-10-18 | Coldsnap, Corp. | Providing single servings of cooled foods and drinks |
USD896572S1 (en) | 2018-08-20 | 2020-09-22 | Yeti Coolers, Llc | Container lid |
USD871133S1 (en) | 2018-10-17 | 2019-12-31 | Yeti Coolers, Llc | Lid |
USD883737S1 (en) | 2018-10-17 | 2020-05-12 | Yeti Coolers, Llc | Lid |
USD897151S1 (en) | 2018-10-17 | 2020-09-29 | Yeti Coolers, Llc | Lid |
USD883738S1 (en) | 2018-10-17 | 2020-05-12 | Yeti Coolers, Llc | Lid |
GB2580933A (en) * | 2019-01-30 | 2020-08-05 | YASIN Omar | Security device for bottles |
US11781808B2 (en) | 2019-04-09 | 2023-10-10 | Coldsnap, Corp. | Brewing and cooling a beverage |
KR20220027812A (en) * | 2019-07-02 | 2022-03-08 | 타이세이카코 카부시키가이샤 | Vials with caps and caps |
FR3098504B1 (en) * | 2019-07-09 | 2021-06-04 | A Raymond Et Cie | locking cap for neck container |
EP4003867B1 (en) * | 2019-07-23 | 2024-04-03 | West Pharmaceutical Services, Inc. | Vial closure assembly |
US11337438B2 (en) | 2020-01-15 | 2022-05-24 | Coldsnap, Corp. | Rapidly cooling food and drinks |
TW202202790A (en) | 2020-06-01 | 2022-01-16 | 美商寇德斯納普公司 | Refrigeration systems for rapidly cooling food and drinks |
US20240050314A1 (en) * | 2020-12-17 | 2024-02-15 | Hoffmann-La Roche Inc. | Closure system and kit |
EP4263378A1 (en) * | 2020-12-17 | 2023-10-25 | F. Hoffmann-La Roche AG | Closure system and kit |
WO2022137489A1 (en) * | 2020-12-25 | 2022-06-30 | 株式会社大協精工 | Plastic cap |
US11827402B2 (en) | 2021-02-02 | 2023-11-28 | Coldsnap, Corp. | Filling aluminum cans aseptically |
FR3125022B1 (en) * | 2021-07-09 | 2023-06-30 | Aptar Stelmi Sas | Closing device for a fluid reservoir |
US11919687B2 (en) * | 2021-11-30 | 2024-03-05 | Owens-Brockway Glass Container Inc. | Package, container, closure assembly, and closure components |
US20230398542A1 (en) * | 2022-06-13 | 2023-12-14 | Cem Corporation | Pressure-Stepped Chemical Reactions and Associated Methods, Systems, Apparatuses, and Articles |
USD1028279S1 (en) | 2022-06-13 | 2024-05-21 | Cem Corporation | Cap for a reaction vessel or the like |
EP4296187A1 (en) * | 2022-06-23 | 2023-12-27 | Capsulit S.P.A. | Closure device, particularly for bottles of lyophilized products, and process for closing a bottle of lyophilized products |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3715175C1 (en) * | 1987-05-07 | 1988-11-24 | Pohl Metall Kunststoff | Cap for infusion and transfusion bottles |
US5314084A (en) * | 1992-08-21 | 1994-05-24 | The West Company, Incorporated | Two piece all plastic seal |
KR0119874Y1 (en) * | 1993-03-02 | 1998-06-01 | 이용학 | Synthetic resin sealing cap for a fluid bottle |
JPH07187216A (en) * | 1993-12-28 | 1995-07-25 | Nissho Corp | Cap for vial |
AUPN476795A0 (en) * | 1995-08-14 | 1995-09-07 | Kalodye, Michael | Tamper-evidencing lid assembly |
JPH09278051A (en) * | 1996-04-09 | 1997-10-28 | Taisei Kako Kk | Crown-form lid having locking mechanism |
US5924584A (en) * | 1997-02-28 | 1999-07-20 | Abbott Laboratories | Container closure with a frangible seal and a connector for a fluid transfer device |
US6659296B2 (en) * | 2000-01-26 | 2003-12-09 | Amersham Health As | Cap for container |
JP2003530253A (en) * | 2000-04-06 | 2003-10-14 | マロ・ヴェー・ファウ | Molded product for use in medicine and method for producing molded product |
NO20020702D0 (en) * | 2002-02-12 | 2002-02-12 | Kristian Bakke Haugen | bottle Cap |
DE10311154A1 (en) * | 2003-03-14 | 2004-09-23 | Helvoet Pharma Belgium N.V. | Pharmaceutical overcap with sealing plug |
JP4526480B2 (en) * | 2003-06-03 | 2010-08-18 | 大成化工株式会社 | Container cap |
DE102004029119A1 (en) * | 2003-06-23 | 2005-01-13 | Helvoet Pharma Belgium N.V. | Closure for lyophilizing comprises a sealing part held in a fixing part that can be arranged on a container in two axially different positions |
NZ554756A (en) * | 2004-10-01 | 2009-08-28 | Belcap Ag | Capsule closure |
BRPI0619244A2 (en) * | 2005-11-30 | 2011-09-20 | Biocorp Rech Et Dev | capping device for a container, process for mounting a device, and container |
FR2893922B1 (en) * | 2005-11-30 | 2010-05-14 | Biocorp Rech Et Dev | CLOSURE DEVICE FOR A CONTAINER AND CONTAINER EQUIPPED WITH SUCH A DEVICE |
FR2900131B1 (en) * | 2006-04-20 | 2010-08-27 | Biocorp Rech Et Dev | CLOSURE DEVICE FOR A CONTAINER AND CONTAINER EQUIPPED WITH SUCH A DEVICE |
FR2912384B1 (en) * | 2007-02-09 | 2009-04-10 | Biocorp Rech Et Dev Sa | CLOSURE DEVICE FOR A CONTAINER, CONTAINER EQUIPPED WITH SUCH A DEVICE AND METHOD FOR CLOSING A LOT OF SUCH A CONTAINER |
-
2008
- 2008-02-11 FR FR0850837A patent/FR2927316B1/en not_active Expired - Fee Related
-
2009
- 2009-02-10 EP EP09710963A patent/EP2242701B1/en active Active
- 2009-02-10 US US12/866,100 patent/US8777031B2/en active Active
- 2009-02-10 CN CN2009801048185A patent/CN101952179B/en active Active
- 2009-02-10 CA CA2714618A patent/CA2714618A1/en not_active Abandoned
- 2009-02-10 WO PCT/FR2009/050209 patent/WO2009101354A1/en active Application Filing
- 2009-02-10 AU AU2009213918A patent/AU2009213918A1/en not_active Abandoned
- 2009-02-10 ES ES09710963T patent/ES2387600T3/en active Active
- 2009-02-10 MX MX2010008842A patent/MX2010008842A/en active IP Right Grant
- 2009-02-10 JP JP2010545542A patent/JP5364869B2/en active Active
- 2009-02-10 PL PL09710963T patent/PL2242701T3/en unknown
-
2012
- 2012-08-13 CY CY20121100729T patent/CY1113066T1/en unknown
Also Published As
Publication number | Publication date |
---|---|
US20110000872A1 (en) | 2011-01-06 |
FR2927316A1 (en) | 2009-08-14 |
WO2009101354A1 (en) | 2009-08-20 |
JP5364869B2 (en) | 2013-12-11 |
FR2927316B1 (en) | 2010-05-14 |
AU2009213918A1 (en) | 2009-08-20 |
ES2387600T3 (en) | 2012-09-27 |
PL2242701T3 (en) | 2012-10-31 |
US8777031B2 (en) | 2014-07-15 |
CN101952179A (en) | 2011-01-19 |
JP2011511741A (en) | 2011-04-14 |
EP2242701A1 (en) | 2010-10-27 |
MX2010008842A (en) | 2010-09-09 |
CY1113066T1 (en) | 2016-04-13 |
CA2714618A1 (en) | 2009-08-20 |
CN101952179B (en) | 2012-02-22 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EP2242701B1 (en) | Stopper device comprising a supporting cap, and container provided with such a device | |
EP1971531B1 (en) | Plug device for a container and container provided with one such device | |
EP2864216B1 (en) | Dispensing and mixing device | |
EP0655045B1 (en) | Multiple compartment dispenser for storing and blending of contents | |
CA1291074C (en) | Liquid substances or solid and liquid material processing device | |
CA2209329C (en) | Device for separate storage, mixing and distribution of mixture of two products, and manufacturing process | |
CH662327A5 (en) | CONTAINER FOR PACKAGING AND DISPENSING A LIQUID PRODUCT AND AT LEAST ONE ADDITIONAL PRODUCT SEPARATED DURING STORAGE. | |
EP0475789A1 (en) | Device to store separately at least two products and to mix them at the time of first use | |
FR2893922A1 (en) | Plug device for medication container e.g. glass vial, has manoeuvring element comprising annular edge engaged between external skirt of ring of cover and lip that forms locking unit and radially extends towards central axis of ring | |
WO1998013006A1 (en) | Connecting device, in particular between a receptacle with a stopper capable of being perforated and a syringe | |
EP0462861A1 (en) | Method for packaging a product in a container, ensuring product preservation during storage and the corresponding packaging unit | |
FR2912384A1 (en) | Closing device for e.g. medicament recipient, has tabs transmitting force and deformed between configuration, where length of tabs presents one value, and another configuration, where length presents another value less than former value | |
FR3094353A1 (en) | CLOSING DEVICE INTENDED TO BE FIXED ON A NECK OF A CONTAINER | |
FR2765861A1 (en) | DEVICE FOR THE SEPARATE PACKAGING OF TWO COMPONENTS AND MANUFACTURING PROCESS | |
EP2007642A1 (en) | Container closure, container equipped with same and method for making same | |
FR2506726A1 (en) | Detachable diaphragm design for a twin chamber container - to allow use of plastics materials with higher tear resistance than polyethylene | |
EP1510363B1 (en) | Paint can closure device with improved fastening means | |
FR2612155A1 (en) | CIRCULAR COVER FOR PULP OF PACKAGING OF PRODUCTS IN BULK | |
FR2466404A1 (en) | CLOSURE DEVICE FOR HIGH VOLUME BOTTLES WITH TWO COMPARTMENTS DESIGNED TO PREVENT CONTAMINATION OF THE CONTENT OF THESE COMPARTMENTS | |
FR2572719A1 (en) | Resealing stopper, particularly for gassy beverages | |
EP4154756B1 (en) | Refill for a cosmetic product dispenser container made from mono-material plastic | |
FR2745793A1 (en) | Stopper for medicine bottle | |
EP0020250B1 (en) | Package, container with a large opening, adapted lid and method of producing such a lid | |
EP0117370B1 (en) | Child-proof stopper with push button | |
FR2978128A1 (en) | Closure assembly for container e.g. bottle, containing hair product, has support surface at base of neck of container, where support surface limits movement of cap along axis during screwing of cap into closed position |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20100803 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK TR |
|
AX | Request for extension of the european patent |
Extension state: AL BA RS |
|
DAX | Request for extension of the european patent (deleted) | ||
GRAP | Despatch of communication of intention to grant a patent |
Free format text: ORIGINAL CODE: EPIDOSNIGR1 |
|
GRAS | Grant fee paid |
Free format text: ORIGINAL CODE: EPIDOSNIGR3 |
|
GRAA | (expected) grant |
Free format text: ORIGINAL CODE: 0009210 |
|
AK | Designated contracting states |
Kind code of ref document: B1 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK TR |
|
REG | Reference to a national code |
Ref country code: GB Ref legal event code: FG4D Free format text: NOT ENGLISH |
|
REG | Reference to a national code |
Ref country code: CH Ref legal event code: EP |
|
REG | Reference to a national code |
Ref country code: AT Ref legal event code: REF Ref document number: 562948 Country of ref document: AT Kind code of ref document: T Effective date: 20120715 |
|
REG | Reference to a national code |
Ref country code: IE Ref legal event code: FG4D Free format text: LANGUAGE OF EP DOCUMENT: FRENCH |
|
REG | Reference to a national code |
Ref country code: DE Ref legal event code: R096 Ref document number: 602009007722 Country of ref document: DE Effective date: 20120816 |
|
REG | Reference to a national code |
Ref country code: SE Ref legal event code: TRGR |
|
REG | Reference to a national code |
Ref country code: NL Ref legal event code: T3 |
|
REG | Reference to a national code |
Ref country code: ES Ref legal event code: FG2A Ref document number: 2387600 Country of ref document: ES Kind code of ref document: T3 Effective date: 20120927 |
|
REG | Reference to a national code |
Ref country code: GR Ref legal event code: EP Ref document number: 20120401803 Country of ref document: GR Effective date: 20120920 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: NO Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20120920 Ref country code: LT Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20120620 Ref country code: FI Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20120620 |
|
REG | Reference to a national code |
Ref country code: PL Ref legal event code: T3 |
|
REG | Reference to a national code |
Ref country code: AT Ref legal event code: MK05 Ref document number: 562948 Country of ref document: AT Kind code of ref document: T Effective date: 20120620 |
|
REG | Reference to a national code |
Ref country code: LT Ref legal event code: MG4D Effective date: 20120620 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: LV Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20120620 Ref country code: HR Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20120620 Ref country code: SI Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20120620 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: IS Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20121020 Ref country code: AT Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20120620 Ref country code: SK Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20120620 Ref country code: RO Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20120620 Ref country code: EE Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20120620 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: PT Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20121022 |
|
PLBE | No opposition filed within time limit |
Free format text: ORIGINAL CODE: 0009261 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: NO OPPOSITION FILED WITHIN TIME LIMIT |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: DK Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20120620 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: CH Payment date: 20130225 Year of fee payment: 5 Ref country code: MC Payment date: 20130121 Year of fee payment: 5 Ref country code: IE Payment date: 20130226 Year of fee payment: 5 Ref country code: CZ Payment date: 20130128 Year of fee payment: 5 Ref country code: LU Payment date: 20130301 Year of fee payment: 5 Ref country code: SE Payment date: 20130227 Year of fee payment: 5 |
|
26N | No opposition filed |
Effective date: 20130321 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: BE Payment date: 20130227 Year of fee payment: 5 Ref country code: PL Payment date: 20130121 Year of fee payment: 5 Ref country code: NL Payment date: 20130224 Year of fee payment: 5 Ref country code: GR Payment date: 20130226 Year of fee payment: 5 |
|
REG | Reference to a national code |
Ref country code: DE Ref legal event code: R097 Ref document number: 602009007722 Country of ref document: DE Effective date: 20130321 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: BG Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20120920 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: CY Payment date: 20130123 Year of fee payment: 5 |
|
REG | Reference to a national code |
Ref country code: FR Ref legal event code: TP Owner name: WEST PHARMACEUTICAL SERVICES DEUTSCHLAND GMBH , DE Effective date: 20130705 |
|
REG | Reference to a national code |
Ref country code: GB Ref legal event code: 732E Free format text: REGISTERED BETWEEN 20130815 AND 20130821 |
|
REG | Reference to a national code |
Ref country code: DE Ref legal event code: R081 Ref document number: 602009007722 Country of ref document: DE Owner name: WEST PHARMACEUTICAL SERVICES DEUTSCHLAND GMBH , DE Free format text: FORMER OWNER: BIOCORP RECHERCHE ET DEVELOPPEMENT, SAINT BEAUZIRE, FR Effective date: 20131114 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: MT Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20120620 |
|
BERE | Be: lapsed |
Owner name: BIOCORP RECHERCHE ET DEVELOPPEMENT Effective date: 20140228 |
|
REG | Reference to a national code |
Ref country code: NL Ref legal event code: V1 Effective date: 20140901 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: MC Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20140228 Ref country code: LU Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20140210 |
|
REG | Reference to a national code |
Ref country code: CH Ref legal event code: PL Ref country code: SE Ref legal event code: EUG |
|
REG | Reference to a national code |
Ref country code: GR Ref legal event code: ML Ref document number: 20120401803 Country of ref document: GR Effective date: 20140903 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: GR Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20140903 Ref country code: LI Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20140228 Ref country code: CY Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20140210 Ref country code: CH Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20140228 Ref country code: NL Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20140901 Ref country code: CZ Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20140210 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: SE Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20140211 |
|
REG | Reference to a national code |
Ref country code: IE Ref legal event code: MM4A |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: BE Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20140228 Ref country code: IE Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20140210 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: PL Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20140210 |
|
REG | Reference to a national code |
Ref country code: PL Ref legal event code: LAPE |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: HU Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT; INVALID AB INITIO Effective date: 20090210 Ref country code: MK Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20120620 |
|
REG | Reference to a national code |
Ref country code: FR Ref legal event code: PLFP Year of fee payment: 8 |
|
REG | Reference to a national code |
Ref country code: FR Ref legal event code: PLFP Year of fee payment: 9 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: TR Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20140210 |
|
REG | Reference to a national code |
Ref country code: FR Ref legal event code: PLFP Year of fee payment: 10 |
|
P01 | Opt-out of the competence of the unified patent court (upc) registered |
Effective date: 20230529 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: ES Payment date: 20240301 Year of fee payment: 16 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: DE Payment date: 20240228 Year of fee payment: 16 Ref country code: GB Payment date: 20240227 Year of fee payment: 16 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: IT Payment date: 20240222 Year of fee payment: 16 Ref country code: FR Payment date: 20240226 Year of fee payment: 16 |