EP2027251A2 - Thermisches wechselbeanspruchungssystem - Google Patents

Thermisches wechselbeanspruchungssystem

Info

Publication number
EP2027251A2
EP2027251A2 EP07783905A EP07783905A EP2027251A2 EP 2027251 A2 EP2027251 A2 EP 2027251A2 EP 07783905 A EP07783905 A EP 07783905A EP 07783905 A EP07783905 A EP 07783905A EP 2027251 A2 EP2027251 A2 EP 2027251A2
Authority
EP
European Patent Office
Prior art keywords
sample
pcr
liquid composition
temperature
sample vessel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
EP07783905A
Other languages
English (en)
French (fr)
Other versions
EP2027251A4 (de
Inventor
George Maltezos
Matthew Johnston
David Goodwin
Axel Scherer
Christopher I. Walker
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
California Institute of Technology CalTech
Original Assignee
California Institute of Technology CalTech
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by California Institute of Technology CalTech filed Critical California Institute of Technology CalTech
Priority to EP12178744.4A priority Critical patent/EP2535427A3/de
Publication of EP2027251A2 publication Critical patent/EP2027251A2/de
Publication of EP2027251A4 publication Critical patent/EP2027251A4/de
Ceased legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0832—Geometry, shape and general structure cylindrical, tube shaped
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/16—Surface properties and coatings
    • B01L2300/168—Specific optical properties, e.g. reflective coatings
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/18—Means for temperature control
    • B01L2300/1805—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
    • B01L2300/1822—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks using Peltier elements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/18—Means for temperature control
    • B01L2300/1805—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
    • B01L2300/1827—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks using resistive heater
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/18—Means for temperature control
    • B01L2300/1838—Means for temperature control using fluid heat transfer medium
    • B01L2300/185—Means for temperature control using fluid heat transfer medium using a liquid as fluid
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • B01L7/02—Water baths; Sand baths; Air baths
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • B01L7/525—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples with physical movement of samples between temperature zones

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
EP07783905A 2006-05-17 2007-05-17 Thermisches wechselbeanspruchungssystem Ceased EP2027251A4 (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP12178744.4A EP2535427A3 (de) 2006-05-17 2007-05-17 Thermisches Wechselbeanspruchungssystem

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US80117806P 2006-05-17 2006-05-17
US83249206P 2006-07-21 2006-07-21
US87317206P 2006-12-06 2006-12-06
US87308406P 2006-12-06 2006-12-06
PCT/US2007/069197 WO2008070198A2 (en) 2006-05-17 2007-05-17 Thermal cycling system

Publications (2)

Publication Number Publication Date
EP2027251A2 true EP2027251A2 (de) 2009-02-25
EP2027251A4 EP2027251A4 (de) 2010-05-05

Family

ID=39492885

Family Applications (2)

Application Number Title Priority Date Filing Date
EP12178744.4A Withdrawn EP2535427A3 (de) 2006-05-17 2007-05-17 Thermisches Wechselbeanspruchungssystem
EP07783905A Ceased EP2027251A4 (de) 2006-05-17 2007-05-17 Thermisches wechselbeanspruchungssystem

Family Applications Before (1)

Application Number Title Priority Date Filing Date
EP12178744.4A Withdrawn EP2535427A3 (de) 2006-05-17 2007-05-17 Thermisches Wechselbeanspruchungssystem

Country Status (3)

Country Link
EP (2) EP2535427A3 (de)
JP (1) JP2009537152A (de)
WO (1) WO2008070198A2 (de)

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US8541238B2 (en) * 2008-09-09 2013-09-24 Douglas Machine Inc. Apparatus and methods for performing real time PCR in array tape
JP5715068B2 (ja) * 2009-01-30 2015-05-07 マイクロニクス， インコーポレイテッド 携帯型高利得蛍光検出システム
EP2415855A4 (de) * 2009-03-31 2014-03-05 Kanagawa Kagaku Gijutsu Akad Hochgeschwindigkeits-genverstärkungsvorrichtung mit flüssigkeitsrückfluss
CN202830041U (zh) * 2009-04-03 2013-03-27 Illumina公司 用于加热生物样本的设备
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GB2512764B (en) * 2009-08-08 2014-12-24 Bibby Scient Ltd An apparatus for treating a test sample
JPWO2011021640A1 (ja) * 2009-08-20 2013-01-24 タカラバイオ株式会社 温度サイクル装置
US8987685B2 (en) 2009-09-09 2015-03-24 Pcr Max Limited Optical system for multiple reactions
JP5343801B2 (ja) * 2009-09-30 2013-11-13 凸版印刷株式会社 遺伝子処理装置用伝熱装置及び遺伝子処理装置
ES2363697B1 (es) * 2009-10-26 2012-04-20 Ingenia Biosystems, S.L. Aparato para el bloqueo de los ácidos nucleicos mediante fotoactivación de agentes intercalantes.
KR102032522B1 (ko) * 2010-01-12 2019-11-08 아람 바이오시스템 주식회사 3단 열대류 장치 및 그 사용법
CA2786569C (en) 2010-01-29 2019-04-09 Micronics, Inc. Sample-to-answer microfluidic cartridge
SG184539A1 (en) 2010-04-09 2012-11-29 Life Technologies Corp Improved thermal uniformity for thermal cycler instrumentation using dynamic control
US9170028B1 (en) 2010-10-06 2015-10-27 Lawrence Livermore National Security, Llc Methods and compositions for rapid thermal cycling
CN103347994A (zh) 2010-12-03 2013-10-09 拜欧法诊断有限公司 热循环设备和相关的方法
JP5687514B2 (ja) * 2011-02-17 2015-03-18 株式会社日立ハイテクノロジーズ 核酸配列解析装置
JP2012187054A (ja) * 2011-03-11 2012-10-04 Hitachi High-Technologies Corp 核酸増幅反応装置
BR112013026451B1 (pt) * 2011-04-15 2021-02-09 Becton, Dickinson And Company sistema e método para realizar ensaios de diagnóstico molecular em várias amostras em paralelo e simultaneamente amplificação em tempo real em pluralidade de câmaras de reação de amplificação
JP5663541B2 (ja) * 2012-09-19 2015-02-04 株式会社日立ハイテクノロジーズ 反応容器，並列処理装置、及びシーケンサ
US20140112829A1 (en) * 2012-10-22 2014-04-24 Qiagen Gaithersburg, Inc. Tube strip handling and heating apparatus
KR20150097764A (ko) 2012-12-21 2015-08-26 마이크로닉스 인코포레이티드. 휴대형 형광 검출 시스템 및 미량분석 카트리지
EP3549674B1 (de) 2012-12-21 2020-08-12 PerkinElmer Health Sciences, Inc. Filme mit geringere elastizität zur mikrofluidischen verwendung
JP6498125B2 (ja) 2012-12-21 2019-04-10 マイクロニクス， インコーポレイテッド 流体回路および関連する製造方法
US10386377B2 (en) 2013-05-07 2019-08-20 Micronics, Inc. Microfluidic devices and methods for performing serum separation and blood cross-matching
CA2911308C (en) 2013-05-07 2021-10-19 Micronics, Inc. Device for preparation and analysis of nucleic acids
EP2994532B1 (de) 2013-05-07 2017-11-15 Micronics, Inc. Verfahren zur herstellung von nukleinsäurehaltigen proben mittels tonmineralien und alkalischen lösungen
US9352502B2 (en) 2013-06-25 2016-05-31 Lawrence Livermore National Security, Llc Porous media heat transfer for injection molding
US20160214110A1 (en) 2013-09-16 2016-07-28 Life Technologies Corporation Apparatuses, Systems and Methods for Providing Thermocycler Thermal Uniformity
KR20160123356A (ko) 2014-02-18 2016-10-25 라이프 테크놀로지스 코포레이션 스케일러블 유전자증폭기를 제공하고 열전 장치를 격리시키기 위한 장치, 시스템 및 방법
US11224873B2 (en) * 2018-03-15 2022-01-18 Kryptos Biotechnologies, Inc. Microfluidic system incorporating light absorbing materials
CN109030133B (zh) * 2018-06-14 2021-04-30 华东交通大学 一种t型试样制作试件的方法
US11440015B2 (en) 2018-08-08 2022-09-13 Lawrence Livermore National Security, Llc Integrated solid-state rapid thermo-cycling system
CN109168298A (zh) * 2018-10-18 2019-01-08 中国科学院合肥物质科学研究院 一种用于pcr检测仪温控系统的散热装置
US10993830B2 (en) 2018-11-09 2021-05-04 Dignitana Ab Scalp cooling apparatus, method, and system
SG10201908290RA (en) * 2019-09-09 2021-04-29 Star Array Pte Ltd Apparatus for polymerase chain reaction of nucleic acid
DE102022109312A1 (de) 2021-05-05 2022-11-10 Frieder Weidhase Vorrichtung zum beschleunigten, miniaturisierten Kühlen und Heizen in der Medizintechnik
CN114854570B (zh) * 2022-07-05 2022-09-02 鲲鹏基因（北京）科技有限责任公司 温控装置、液冷温控系统及pcr仪

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JPH07185363A (ja) * 1993-12-27 1995-07-25 Shuji Ueda 加熱冷却器
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Also Published As

Publication number Publication date
WO2008070198A2 (en) 2008-06-12
EP2535427A2 (de) 2012-12-19
JP2009537152A (ja) 2009-10-29
EP2535427A3 (de) 2013-04-24
WO2008070198A3 (en) 2009-04-16
WO2008070198A8 (en) 2008-12-24
EP2027251A4 (de) 2010-05-05

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