EP1996937A4 - Materiels génétiques et utilisations correspondantes - Google Patents
Materiels génétiques et utilisations correspondantesInfo
- Publication number
- EP1996937A4 EP1996937A4 EP07752549A EP07752549A EP1996937A4 EP 1996937 A4 EP1996937 A4 EP 1996937A4 EP 07752549 A EP07752549 A EP 07752549A EP 07752549 A EP07752549 A EP 07752549A EP 1996937 A4 EP1996937 A4 EP 1996937A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- genetic packages
- packages
- genetic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1037—Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1044—Preparation or screening of libraries displayed on scaffold proteins
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Crystallography & Structural Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Virology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US74341006P | 2006-03-06 | 2006-03-06 | |
US74362206P | 2006-03-21 | 2006-03-21 | |
US11/528,927 US20070191272A1 (en) | 2005-09-27 | 2006-09-27 | Proteinaceous pharmaceuticals and uses thereof |
US11/528,950 US20070212703A1 (en) | 2005-09-27 | 2006-09-27 | Proteinaceous pharmaceuticals and uses thereof |
PCT/US2007/005857 WO2007103455A2 (fr) | 2006-03-06 | 2007-03-06 | Materiels génétiques et utilisations correspondantes |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1996937A2 EP1996937A2 (fr) | 2008-12-03 |
EP1996937A4 true EP1996937A4 (fr) | 2009-04-08 |
Family
ID=38475542
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP07752636.6A Active EP1996220B2 (fr) | 2005-09-27 | 2007-03-06 | Polymères recombinés non structurés et utilisations correspondantes |
EP07752549A Withdrawn EP1996937A4 (fr) | 2006-03-06 | 2007-03-06 | Materiels génétiques et utilisations correspondantes |
EP20140189047 Ceased EP2863222A1 (fr) | 2006-03-06 | 2007-03-06 | Polymères recombinants non structurés et leurs utilisations |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP07752636.6A Active EP1996220B2 (fr) | 2005-09-27 | 2007-03-06 | Polymères recombinés non structurés et utilisations correspondantes |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP20140189047 Ceased EP2863222A1 (fr) | 2006-03-06 | 2007-03-06 | Polymères recombinants non structurés et leurs utilisations |
Country Status (6)
Country | Link |
---|---|
EP (3) | EP1996220B2 (fr) |
AU (2) | AU2007223888A1 (fr) |
CA (1) | CA2644712C (fr) |
DK (1) | DK2402754T4 (fr) |
SI (1) | SI2402754T2 (fr) |
WO (2) | WO2007103455A2 (fr) |
Families Citing this family (79)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PT1583562E (pt) | 2003-01-06 | 2011-09-19 | Angiochem Inc | Angiopep-1, compostos relacionados, e suas utilizações |
US7855279B2 (en) | 2005-09-27 | 2010-12-21 | Amunix Operating, Inc. | Unstructured recombinant polymers and uses thereof |
US7846445B2 (en) | 2005-09-27 | 2010-12-07 | Amunix Operating, Inc. | Methods for production of unstructured recombinant polymers and uses thereof |
US20130172274A1 (en) | 2005-12-20 | 2013-07-04 | Duke University | Methods and compositions for delivering active agents with enhanced pharmacological properties |
CA2634034A1 (fr) | 2005-12-20 | 2007-06-28 | Duke University | Procedes et compositions pour l'administration d'agents actifs a proprietes pharmacologiques ameliorees |
US8841255B2 (en) | 2005-12-20 | 2014-09-23 | Duke University | Therapeutic agents comprising fusions of vasoactive intestinal peptide and elastic peptides |
WO2007103455A2 (fr) | 2006-03-06 | 2007-09-13 | Amunix, Inc. | Materiels génétiques et utilisations correspondantes |
US9365634B2 (en) | 2007-05-29 | 2016-06-14 | Angiochem Inc. | Aprotinin-like polypeptides for delivering agents conjugated thereto to tissues |
SI2173890T1 (sl) | 2007-06-21 | 2011-06-30 | Univ Muenchen Tech | Biološko aktivni proteini, ki imajo povečano in vivo in/ali in vitro stabilnost |
MX2010001684A (es) * | 2007-08-15 | 2010-04-21 | Amunix Inc | Composiciones y metodos para modificar propiedades de polipeptidos biologicamente activos. |
EP2926825A1 (fr) | 2008-06-27 | 2015-10-07 | Duke University | Agents thérapeutiques comprenant des peptides de type élastine |
JP2012505637A (ja) | 2008-10-15 | 2012-03-08 | アンジオケム,インコーポレーテッド | Glp−1アゴニストのコンジュゲート及びその使用 |
CN102307904A (zh) | 2008-12-05 | 2012-01-04 | 安吉奥开米公司 | 神经降压素或神经降压素类似物的缀合物及其用途 |
AU2014206217B2 (en) * | 2009-02-03 | 2015-09-17 | Amunix Pharmaceuticals, Inc. | Extended recombinant polypeptides and compositions comprising same |
AU2015218510B2 (en) * | 2009-02-03 | 2016-11-10 | Amunix Pharmaceuticals, Inc. | Extended recombinant polypeptides and compositions comprising same |
US8703717B2 (en) | 2009-02-03 | 2014-04-22 | Amunix Operating Inc. | Growth hormone polypeptides and methods of making and using same |
MX362028B (es) | 2009-02-03 | 2019-01-04 | Amunix Pharmaceuticals Inc | Polipeptidos recombinantes extendidos y composiciones que comprenden los mismos. |
US8680050B2 (en) | 2009-02-03 | 2014-03-25 | Amunix Operating Inc. | Growth hormone polypeptides fused to extended recombinant polypeptides and methods of making and using same |
US9173891B2 (en) | 2009-04-20 | 2015-11-03 | Angiochem, Inc. | Treatment of ovarian cancer using an anticancer agent conjugated to an angiopep-2 analog |
ES2705249T3 (es) * | 2009-06-08 | 2019-03-22 | Amunix Operating Inc | Polipéptidos reguladores de glucosa y métodos para su producción y uso |
KR101813727B1 (ko) * | 2009-06-08 | 2018-01-02 | 아뮤닉스 오퍼레이팅 인코포레이티드 | 성장 호르몬 폴리펩타이드 및 이를 제조하고 사용하는 방법 |
US9849188B2 (en) | 2009-06-08 | 2017-12-26 | Amunix Operating Inc. | Growth hormone polypeptides and methods of making and using same |
MX354555B (es) * | 2009-06-08 | 2018-03-09 | Amunix Operating Inc | Polipeptidos de la hormona de crecimiento y metodos de preparacion y su uso. |
RU2012103240A (ru) | 2009-07-02 | 2013-08-10 | Ангиокем Инк. | Мультимерные пептидные конъюгаты и их применение |
AU2010290077C1 (en) | 2009-08-24 | 2015-12-03 | Bioverativ Therapeutics Inc. | Coagulation factor IX compositions and methods of making and using same |
EP2502939B1 (fr) * | 2009-11-19 | 2016-01-27 | Zhejiang University | Protéine non naturelle de type collagène et son utilisation |
ES2880038T3 (es) | 2009-12-06 | 2021-11-23 | Bioverativ Therapeutics Inc | Polipéptidos quiméricos e híbridos de factor VIII-Fc, y métodos de uso de los mismos |
US8557961B2 (en) | 2010-04-02 | 2013-10-15 | Amunix Operating Inc. | Alpha 1-antitrypsin compositions and methods of making and using same |
EP2552967A4 (fr) * | 2010-04-02 | 2014-10-08 | Amunix Operating Inc | Protéines de fusion liantes, conjugués protéines de fusion liantes-médicaments, conjugués xten-médicaments et procédés pour les préparer et les utiliser |
AR081361A1 (es) | 2010-04-30 | 2012-08-29 | Molecular Partners Ag | Proteinas de union modificadas que inhiben la interaccion de receptor del factor de crecimiento endotelial vascular de glicoproteina a vegf-a |
EA024755B1 (ru) | 2010-05-21 | 2016-10-31 | ИксЭль-ПРОТЕИН ГМБХ | Биосинтетические нерегулярные спиральные полипептиды пролина/аланина и их применения |
CA2802635A1 (fr) | 2010-06-18 | 2011-12-22 | Xiberscience Gmbh | Peptides en tant qu'agents actifs pour stabiliser des barrieres biologiques |
CN103140237A (zh) | 2010-07-09 | 2013-06-05 | 比奥根艾迪克依蒙菲利亚公司 | 因子ix多肽及其使用方法 |
CA2818990C (fr) | 2010-11-26 | 2021-06-15 | Molecular Partners Ag | Proteines de repetition concues se liant a l'albumine serique |
PL2717898T3 (pl) | 2011-06-10 | 2019-06-28 | Bioverativ Therapeutics Inc. | Związki o działaniu prokoagulacyjnym i sposoby ich stosowania |
RS58578B1 (sr) | 2011-07-08 | 2019-05-31 | Bioverativ Therapeutics Inc | Faktor viii himernih i hibridnih polipeptida i postupci za njihovu upotrebu |
US10656167B2 (en) | 2011-07-25 | 2020-05-19 | Bioverativ Therapeutics Inc. | Assays to monitor bleeding disorders |
BR112014017165B1 (pt) * | 2012-01-12 | 2023-05-02 | Bioverativ Therapeutics Inc | Proteína quimérica compreendendo uma proteína de fator viii, composição farmacêutica, e seus usos |
EP3549953A1 (fr) | 2012-02-15 | 2019-10-09 | Bioverativ Therapeutics Inc. | Protéines de facteur viii de recombinaison |
ES2771208T3 (es) | 2012-02-15 | 2020-07-06 | Bioverativ Therapeutics Inc | Composiciones de factor VIII y métodos de preparación y uso de las mismas |
MX366864B (es) | 2012-02-27 | 2019-07-26 | Amunix Operating Inc | Composiciones de conjugados de xten y métodos para realizarlas. |
ES2753135T3 (es) | 2012-05-07 | 2020-04-07 | Allergan Inc | Método de tratamiento de DMAE en pacientes resistentes a terapia anti-VEGF |
US9289507B2 (en) | 2012-05-17 | 2016-03-22 | Extend Biosciences, Inc. | Carriers for improved drug delivery |
BR112014032316A2 (pt) | 2012-06-28 | 2017-06-27 | Molecular Partners Ag | proteínas de repetição de anquirina projetadas que se ligam ao fator de crescimento derivado de plaqueta |
EP2870250B2 (fr) | 2012-07-06 | 2022-06-29 | Bioverativ Therapeutics Inc. | Lignée cellulaire exprimant des polypeptides de facteur viii à une seule chaîne et ses utilisations |
CN110054699A (zh) | 2012-07-11 | 2019-07-26 | 比奥贝拉蒂治疗公司 | 具有xten和血管性血友病因子蛋白的因子viii复合物、及其用途 |
TWI810729B (zh) | 2012-09-25 | 2023-08-01 | 美商百歐維拉提夫治療公司 | Fix多肽的應用 |
EP2738180A1 (fr) | 2012-11-30 | 2014-06-04 | Molecular Partners AG | Protéines de liaison comportant au moins deux domaines de liaison ciblant HER2 |
AU2014228938B2 (en) | 2013-03-15 | 2019-05-02 | Bioverativ Therapeutics Inc. | Factor IX polypeptide formulations |
WO2015022326A1 (fr) | 2013-08-12 | 2015-02-19 | Xiber Science Gmbh | Peptides en tant qu'agents actifs pour le traitement d'un dysfonctionnement du greffon primaire |
WO2015023891A2 (fr) | 2013-08-14 | 2015-02-19 | Biogen Idec Ma Inc. | Fusions de facteur vii-xten et leurs utilisations |
EP3065761B1 (fr) | 2013-11-05 | 2020-01-08 | Allergan, Inc. | Procédé de traitement d'états de santé de l'oeil par un darpin anti-vegf |
EP3065769A4 (fr) | 2013-11-08 | 2017-05-31 | Biogen MA Inc. | Composé de fusion procoagulant |
CN106456718A (zh) | 2014-01-10 | 2017-02-22 | 比奥根Ma公司 | 因子viii嵌合蛋白及其用途 |
BR112016027897A2 (pt) | 2014-06-18 | 2017-10-24 | Albert Einstein College Medicine Inc | polipeptídio multimérico, ácido nucleico, vetor de expressão recombinante, célula hospedeira geneticamente modificada, composição, método, e, método de tratamento de uma infecção num indivíduo |
US9789197B2 (en) | 2014-10-22 | 2017-10-17 | Extend Biosciences, Inc. | RNAi vitamin D conjugates |
WO2016065052A1 (fr) | 2014-10-22 | 2016-04-28 | Extend Biosciences, Inc. | Conjugués insuline vitamine d |
EP3220961B1 (fr) | 2014-10-22 | 2023-07-05 | Extend Biosciences, Inc. | Conjugués de vitamine d thérapeutiques |
ES2953482T3 (es) | 2015-04-02 | 2023-11-13 | Molecular Partners Ag | Dominios de repetición de anquirina diseñados con especificidad de unión para la albúmina sérica |
US11208452B2 (en) | 2015-06-02 | 2021-12-28 | Novo Nordisk A/S | Insulins with polar recombinant extensions |
ES2826827T3 (es) | 2015-06-15 | 2021-05-19 | Angiochem Inc | Métodos para el tratamiento de carcinomatosis leptomeníngea |
EA201890423A1 (ru) | 2015-08-03 | 2018-07-31 | Биовератив Терапьютикс Инк. | Слитые белки фактора ix, способы их получения и применения |
AU2016315656A1 (en) | 2015-08-28 | 2018-02-01 | Amunix Pharmaceuticals, Inc. | Chimeric polypeptide assembly and methods of making and using the same |
MA43348A (fr) | 2015-10-01 | 2018-08-08 | Novo Nordisk As | Conjugués de protéines |
EP3458095A4 (fr) | 2016-05-18 | 2019-11-27 | Albert Einstein College of Medicine | Variants de polypeptides pd-l1, polypeptides multimères modulateurs des lymphocytes t et procédés d'utilisation correspondants |
KR20190019068A (ko) | 2016-05-18 | 2019-02-26 | 큐 바이오파마, 인크. | T-세포 조절 다량체 폴리펩타이드 및 이의 사용 방법 |
EP3558339B1 (fr) | 2016-12-22 | 2024-01-24 | Cue Biopharma, Inc. | Polypeptides multimères modulateurs des lymphocytes t et leurs méthodes d'utilisation |
EP3565829A4 (fr) | 2017-01-09 | 2021-01-27 | Cue Biopharma, Inc. | Polypeptides multimères modulateurs de lymphocytes t et leurs procédés d'utilisation |
CN110505885A (zh) | 2017-04-05 | 2019-11-26 | 诺和诺德股份有限公司 | 寡聚体延伸的胰岛素-Fc缀合物 |
CN111315768A (zh) | 2017-09-07 | 2020-06-19 | 库尔生物制药有限公司 | 具有缀合位点的t细胞调节性多聚体多肽及其使用方法 |
WO2019139896A1 (fr) | 2018-01-09 | 2019-07-18 | Cue Biopharma, Inc. | Polypeptides multimères modulateurs de lymphocytes t et leurs procédés d'utilisation |
WO2019201855A1 (fr) * | 2018-04-16 | 2019-10-24 | Swedish Orphan Biovitrum Ab (Publ) | Protéine de fusion lysosomale |
TW202039542A (zh) | 2018-12-19 | 2020-11-01 | 美商庫爾生物製藥有限公司 | 多聚體t細胞調節多肽及其使用方法 |
EP3935080A4 (fr) | 2019-03-06 | 2023-04-05 | Cue Biopharma, Inc. | Polypeptides multimères modulateurs des lymphocytes t et leurs méthodes d'utilisation |
EP4192495A1 (fr) | 2020-08-07 | 2023-06-14 | Bristol-Myers Squibb Company | Fgf21 combiné à des antagonistes de ccr2/5 pour le traitement de la fibrose |
CN115925995A (zh) | 2020-09-30 | 2023-04-07 | 北京质肽生物医药科技有限公司 | 多肽缀合物和使用方法 |
US20240123031A1 (en) | 2020-11-25 | 2024-04-18 | Bristol-Myers Squibb Company | Methods of treating liver diseases |
WO2022123459A1 (fr) | 2020-12-11 | 2022-06-16 | Friedrich Miescher Institute For Biomedical Research | Protéines de liaison à hdac6 et leur utilisation antivirale |
CN115083016A (zh) * | 2022-06-09 | 2022-09-20 | 广州紫为云科技有限公司 | 一种基于单目摄像机的面向小目标手部隔空交互方法与装置 |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DD257197A1 (de) † | 1987-01-28 | 1988-06-08 | Univ Dresden Tech | Verfahren zur herstellung von immobilisierten, in ihrer biologischen aktivitaet stabilisierten und in ihren pharmakologischen eigenschaften modifizierten insulinpraeparationen |
FR2647677B1 (fr) * | 1989-05-31 | 1991-09-27 | Roussel Uclaf | Nouvelles micro-proteines, procede de preparation et application a titre de medicaments de ces nouvelles micro-proteines |
SK60893A3 (en) † | 1990-12-13 | 1993-10-06 | Upjohn Co | Fusion polypeptides |
US5833911A (en) † | 1995-05-31 | 1998-11-10 | Johnson & Johnson Medical, Inc. | Method for forming a glove using a folded glove form |
AU5065198A (en) † | 1996-11-15 | 1998-06-10 | Maria Grazia Masucci | Fusion proteins having increased half-lives |
US20050260605A1 (en) * | 1998-02-11 | 2005-11-24 | Maxygen, Inc. | Targeting of genetic vaccine vectors |
AU3289199A (en) * | 1998-02-11 | 1999-08-30 | Maxygen, Inc. | Antigen library immunization |
US20050287153A1 (en) * | 2002-06-28 | 2005-12-29 | Genentech, Inc. | Serum albumin binding peptides for tumor targeting |
US20030049689A1 (en) * | 2000-12-14 | 2003-03-13 | Cynthia Edwards | Multifunctional polypeptides |
PE20020908A1 (es) * | 2001-03-21 | 2002-10-26 | Cell Therapeutics Inc | Produccion recombinante de polimeros polianionicos y uso de de los mismos |
EP1841787A2 (fr) * | 2005-01-25 | 2007-10-10 | Cell Therapeutics, Inc. | Conjugues de proteine biologiquement actives possedant une demi-vie in vivo modifiee |
CA2634034A1 (fr) † | 2005-12-20 | 2007-06-28 | Duke University | Procedes et compositions pour l'administration d'agents actifs a proprietes pharmacologiques ameliorees |
WO2007103455A2 (fr) | 2006-03-06 | 2007-09-13 | Amunix, Inc. | Materiels génétiques et utilisations correspondantes |
WO2008049711A1 (fr) † | 2006-10-27 | 2008-05-02 | Novo Nordisk A/S | Insuline à peptide ajouté |
-
2007
- 2007-03-06 WO PCT/US2007/005857 patent/WO2007103455A2/fr active Application Filing
- 2007-03-06 AU AU2007223888A patent/AU2007223888A1/en not_active Abandoned
- 2007-03-06 EP EP07752636.6A patent/EP1996220B2/fr active Active
- 2007-03-06 EP EP07752549A patent/EP1996937A4/fr not_active Withdrawn
- 2007-03-06 AU AU2007223855A patent/AU2007223855B2/en active Active
- 2007-03-06 DK DK11172812.7T patent/DK2402754T4/da active
- 2007-03-06 SI SI200731588T patent/SI2402754T2/sl unknown
- 2007-03-06 WO PCT/US2007/005952 patent/WO2007103515A2/fr active Application Filing
- 2007-03-06 EP EP20140189047 patent/EP2863222A1/fr not_active Ceased
- 2007-03-06 CA CA2644712A patent/CA2644712C/fr active Active
Non-Patent Citations (4)
Title |
---|
BULAJ GRZEGORZ ET AL: "Efficient oxidative folding of conotoxins and the radiation of venomous cone snails.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 100, no. Supplement 2, 25 November 2003 (2003-11-25), pages 14562 - 14568, XP002515375, ISSN: 0027-8424 * |
CHEN X J ET AL: "Site-directed mutations in a highly conserved region of Bacillus thuringiensis delta-endotoxin affect inhibition of short circuit current across Bombyx mori midguts.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 1 OCT 1993, vol. 90, no. 19, 1 October 1993 (1993-10-01), pages 9041 - 9045, XP002515378, ISSN: 0027-8424 * |
GOMEZ-DUARTE O G ET AL: "Expression of fragment C of tetanus toxin fused to a carboxyl-terminal fragment of diphtheria toxin in Salmonella typhi CVD 908 vaccine strain", VACCINE, BUTTERWORTH SCIENTIFIC. GUILDFORD, GB, vol. 13, no. 16, 1 November 1995 (1995-11-01), pages 1596 - 1602, XP004057422, ISSN: 0264-410X * |
PI C ET AL: "Analysis of expressed sequence tags from the venom ducts of Conus striatus: focusing on the expression profile of conotoxins", BIOCHIMIE, MASSON, PARIS, FR, vol. 88, no. 2, 1 February 2006 (2006-02-01), pages 131 - 140, XP025066514, ISSN: 0300-9084, [retrieved on 20060201] * |
Also Published As
Publication number | Publication date |
---|---|
DK2402754T3 (en) | 2015-01-12 |
EP2863222A1 (fr) | 2015-04-22 |
WO2007103455A3 (fr) | 2007-11-29 |
AU2007223888A1 (en) | 2007-09-13 |
EP1996220B2 (fr) | 2023-08-16 |
EP1996220B1 (fr) | 2013-05-08 |
SI2402754T1 (sl) | 2015-02-27 |
EP1996220A4 (fr) | 2009-04-29 |
EP1996937A2 (fr) | 2008-12-03 |
CA2644712A1 (fr) | 2007-09-13 |
EP1996220A2 (fr) | 2008-12-03 |
WO2007103515A3 (fr) | 2008-04-03 |
WO2007103515A2 (fr) | 2007-09-13 |
CA2644712C (fr) | 2016-09-13 |
DK2402754T4 (da) | 2023-08-28 |
WO2007103455A2 (fr) | 2007-09-13 |
AU2007223855A1 (en) | 2007-09-13 |
AU2007223855B2 (en) | 2013-05-16 |
SI2402754T2 (sl) | 2023-09-29 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EP1996937A4 (fr) | Materiels génétiques et utilisations correspondantes | |
ZA200810323B (en) | Fkbp-l and uses thereof | |
IL195658A0 (en) | Anti-nkg2a antibodies and uses thereof | |
SI2064327T1 (sl) | DBAIT in njegova uporaba | |
ZA200902823B (en) | Oligoribonucleotides and uses thereof | |
IL196397A0 (en) | Prlr-specific antibody and uses thereof | |
AU313874S (en) | Package | |
IL194751A0 (en) | Drugs and uses | |
GB0621160D0 (en) | Compounds and uses thereof | |
HK1133552A1 (en) | Carboranylporphyrins and uses thereof | |
IL196861A0 (en) | Antibodies against ccr5 and uses thereof | |
IL195525A0 (en) | Replikin peptides and uses thereof | |
IL193469A0 (en) | Novel lipases and uses thereof | |
EP2124908A4 (fr) | Composés et utilisations de ceux-ci | |
GB0604187D0 (en) | Peptide and uses thereof | |
EP2120563A4 (fr) | Composés et leurs utilisations | |
EP2099459A4 (fr) | Composés et leurs utilisations | |
GB0603717D0 (en) | Electricity-generate and store | |
SI2032708T1 (sl) | Rekombinantni novirabdovirusi in njihove uporabe | |
IL192800A0 (en) | Fgf2-binding peptides and uses thereof | |
EP2120957A4 (fr) | Composés et leurs utilisations | |
ZA200807233B (en) | Novel lipases and uses thereof | |
GB0621665D0 (en) | Blogmail and podmail | |
GB2444960B (en) | Combined pseudoscope and hyperscope | |
GB0615557D0 (en) | Compounds and Uses Thereof |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20081006 |
|
AK | Designated contracting states |
Kind code of ref document: A2 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20090305 |
|
17Q | First examination report despatched |
Effective date: 20090717 |
|
RAP1 | Party data changed (applicant data changed or rights of an application transferred) |
Owner name: AMUNIX OPERATING INC. |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20110421 |