EP1996937A4 - Materiels génétiques et utilisations correspondantes - Google Patents

Materiels génétiques et utilisations correspondantes

Info

Publication number
EP1996937A4
EP1996937A4 EP07752549A EP07752549A EP1996937A4 EP 1996937 A4 EP1996937 A4 EP 1996937A4 EP 07752549 A EP07752549 A EP 07752549A EP 07752549 A EP07752549 A EP 07752549A EP 1996937 A4 EP1996937 A4 EP 1996937A4
Authority
EP
European Patent Office
Prior art keywords
genetic packages
packages
genetic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP07752549A
Other languages
German (de)
English (en)
Other versions
EP1996937A2 (fr
Inventor
Volker Schellenberger
Willem P Stemmer
Chia-Wei Wang
Michael D Scholle
Mikhail Popkov
Nathaniel C Gordon
Andreas Crameri
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Amunix Pharmaceuticals Inc
Original Assignee
Amunix Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38475542&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EP1996937(A4) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US11/528,950 external-priority patent/US20070212703A1/en
Application filed by Amunix Inc filed Critical Amunix Inc
Publication of EP1996937A2 publication Critical patent/EP1996937A2/fr
Publication of EP1996937A4 publication Critical patent/EP1996937A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034Isolating an individual clone by screening libraries
    • C12N15/1037Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034Isolating an individual clone by screening libraries
    • C12N15/1044Preparation or screening of libraries displayed on scaffold proteins
EP07752549A 2006-03-06 2007-03-06 Materiels génétiques et utilisations correspondantes Withdrawn EP1996937A4 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US74341006P 2006-03-06 2006-03-06
US74362206P 2006-03-21 2006-03-21
US11/528,950 US20070212703A1 (en) 2005-09-27 2006-09-27 Proteinaceous pharmaceuticals and uses thereof
US11/528,927 US20070191272A1 (en) 2005-09-27 2006-09-27 Proteinaceous pharmaceuticals and uses thereof
PCT/US2007/005857 WO2007103455A2 (fr) 2006-03-06 2007-03-06 Materiels génétiques et utilisations correspondantes

Publications (2)

Publication Number Publication Date
EP1996937A2 EP1996937A2 (fr) 2008-12-03
EP1996937A4 true EP1996937A4 (fr) 2009-04-08

Family

ID=38475542

Family Applications (3)

Application Number Title Priority Date Filing Date
EP07752549A Withdrawn EP1996937A4 (fr) 2006-03-06 2007-03-06 Materiels génétiques et utilisations correspondantes
EP07752636.6A Active EP1996220B2 (fr) 2005-09-27 2007-03-06 Polymères recombinés non structurés et utilisations correspondantes
EP20140189047 Ceased EP2863222A1 (fr) 2006-03-06 2007-03-06 Polymères recombinants non structurés et leurs utilisations

Family Applications After (2)

Application Number Title Priority Date Filing Date
EP07752636.6A Active EP1996220B2 (fr) 2005-09-27 2007-03-06 Polymères recombinés non structurés et utilisations correspondantes
EP20140189047 Ceased EP2863222A1 (fr) 2006-03-06 2007-03-06 Polymères recombinants non structurés et leurs utilisations

Country Status (6)

Country Link
EP (3) EP1996937A4 (fr)
AU (2) AU2007223855B2 (fr)
CA (1) CA2644712C (fr)
DK (1) DK2402754T4 (fr)
SI (1) SI2402754T2 (fr)
WO (2) WO2007103455A2 (fr)

Families Citing this family (79)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI1583562T1 (sl) 2003-01-06 2011-10-28 Angiochem Inc AngioPep-1, sorodne spojine in njihove uporabe
US7846445B2 (en) 2005-09-27 2010-12-07 Amunix Operating, Inc. Methods for production of unstructured recombinant polymers and uses thereof
US7855279B2 (en) 2005-09-27 2010-12-21 Amunix Operating, Inc. Unstructured recombinant polymers and uses thereof
US20130172274A1 (en) 2005-12-20 2013-07-04 Duke University Methods and compositions for delivering active agents with enhanced pharmacological properties
US8841255B2 (en) 2005-12-20 2014-09-23 Duke University Therapeutic agents comprising fusions of vasoactive intestinal peptide and elastic peptides
US8334257B2 (en) 2005-12-20 2012-12-18 Duke University Methods and compositions for delivering active agents with enhanced pharmacological properties
SI2402754T2 (sl) 2006-03-06 2023-09-29 Amunix Operating Inc. Nestrukturirani rekombinantni polimeri in njihove uporabe
US9365634B2 (en) 2007-05-29 2016-06-14 Angiochem Inc. Aprotinin-like polypeptides for delivering agents conjugated thereto to tissues
CN101970678B (zh) 2007-06-21 2014-08-20 慕尼黑科技大学 具有增加的体内和/或体外稳定性的生物学活性蛋白
CA2695374A1 (fr) * 2007-08-15 2009-02-19 Amunix, Inc. Compositions et procedes d'amelioration de la production de polypeptides recombines
EP3412300A1 (fr) 2008-06-27 2018-12-12 Duke University Agents thérapeutiques comprenant des peptides de type élastine
JP2012505637A (ja) 2008-10-15 2012-03-08 アンジオケム,インコーポレーテッド Glp−1アゴニストのコンジュゲート及びその使用
JP5759379B2 (ja) 2008-12-05 2015-08-05 アンジオケム インコーポレーテッド ニューロテンシンまたはニューロテンシンアナログおよびその使用
AU2015218510B2 (en) * 2009-02-03 2016-11-10 Amunix Pharmaceuticals, Inc. Extended recombinant polypeptides and compositions comprising same
US8716448B2 (en) * 2009-02-03 2014-05-06 Amunix Operating Inc. Coagulation factor VII compositions and methods of making and using same
US8703717B2 (en) 2009-02-03 2014-04-22 Amunix Operating Inc. Growth hormone polypeptides and methods of making and using same
US8680050B2 (en) 2009-02-03 2014-03-25 Amunix Operating Inc. Growth hormone polypeptides fused to extended recombinant polypeptides and methods of making and using same
CN102348715B (zh) 2009-02-03 2017-12-08 阿穆尼克斯运营公司 延伸重组多肽和包含该延伸重组多肽的组合物
AU2014206217B2 (en) * 2009-02-03 2015-09-17 Amunix Pharmaceuticals, Inc. Extended recombinant polypeptides and compositions comprising same
WO2010121379A1 (fr) 2009-04-20 2010-10-28 Angiochem Inc Traitement d'un cancer de l'ovaire à l'aide d'un agent anticancéreux conjugué à un analogue d'angiopep-2
US9849188B2 (en) 2009-06-08 2017-12-26 Amunix Operating Inc. Growth hormone polypeptides and methods of making and using same
KR101813727B1 (ko) * 2009-06-08 2018-01-02 아뮤닉스 오퍼레이팅 인코포레이티드 성장 호르몬 폴리펩타이드 및 이를 제조하고 사용하는 방법
PT2440228T (pt) 2009-06-08 2018-12-24 Amunix Operating Inc Polipéptidos de regulação da glicose e métodos de preparação e utilização dos mesmos
EP2440241B1 (fr) * 2009-06-08 2017-08-09 Amunix Operating Inc. Polypeptides d'hormone de croissance et leurs procédés de production et d'utilisation
AU2010268726A1 (en) * 2009-07-02 2012-01-19 Angiochem Inc. Multimeric peptide conjugates and uses thereof
EP2502939B1 (fr) * 2009-11-19 2016-01-27 Zhejiang University Protéine non naturelle de type collagène et son utilisation
WO2011069164A2 (fr) 2009-12-06 2011-06-09 Biogen Idec Ma Inc. Polypeptides chimériques et hybrides de facteur viii-fc, et procédés d'utilisation de ceux-ci
WO2011123830A2 (fr) * 2010-04-02 2011-10-06 Amunix Operating Inc. Compositions d'alpha 1-antitrypsine, leurs procédés de préparation et d'utilisation
WO2011123813A2 (fr) * 2010-04-02 2011-10-06 Amunix Operating Inc. Protéines de fusion liantes, conjugués protéines de fusion liantes-médicaments, conjugués xten-médicaments et procédés pour les préparer et les utiliser
AR081361A1 (es) 2010-04-30 2012-08-29 Molecular Partners Ag Proteinas de union modificadas que inhiben la interaccion de receptor del factor de crecimiento endotelial vascular de glicoproteina a vegf-a
CN102883734B (zh) 2010-05-21 2018-01-02 Xl-蛋白有限责任公司 生物合成的脯氨酸/丙氨酸无规卷曲多肽及其用途
WO2011157819A2 (fr) 2010-06-18 2011-12-22 Xiberscience Gmbh Peptides en tant qu'agents actifs pour stabiliser des barrières biologiques
KR20230156435A (ko) 2010-07-09 2023-11-14 바이오버라티브 테라퓨틱스 인크. 인자 ix 폴리펩티드 및 이들의 사용 방법
ES2758352T3 (es) 2010-11-26 2020-05-05 Molecular Partners Ag Proteínas de repetición diseñadas que se une a la seroalbúmina
WO2012170969A2 (fr) 2011-06-10 2012-12-13 Biogen Idec Ma Inc. Composés pro-coagulants et leurs procédés d'utilisation
MY180714A (en) 2011-07-08 2020-12-07 Bioverativ Therapeutics Inc Factor viii chimeric and hybrid polypeptides, and methods of use thereof
EA028914B1 (ru) 2011-07-25 2018-01-31 Байоджен Хемофилия Инк. Исследования для мониторинга нарушений свертываемости крови
NZ626945A (en) * 2012-01-12 2016-10-28 Biogen Ma Inc Chimeric factor viii polypeptides and uses thereof
KR20190094480A (ko) 2012-02-15 2019-08-13 바이오버라티브 테라퓨틱스 인크. 재조합 인자 viii 단백질
CN111548418A (zh) 2012-02-15 2020-08-18 比奥贝拉蒂治疗公司 因子viii组合物及其制备和使用方法
CN117462693A (zh) 2012-02-27 2024-01-30 阿穆尼克斯运营公司 Xten缀合组合物和制造其的方法
EP3646880A1 (fr) 2012-05-07 2020-05-06 Allergan, Inc. Procédé de traitement d'amd chez des patients souffrant d'un état réfractaire à la thérapie anti-vegf
MX349035B (es) 2012-05-17 2017-07-07 Extend Biosciences Inc Portadores para el suministro mejorado de farmaco.
AU2013283296A1 (en) 2012-06-28 2015-02-05 Molecular Partners Ag Designed ankyrin repeat proteins binding to platelet-derived growth factor
EP3404105A1 (fr) 2012-07-06 2018-11-21 Bioverativ Therapeutics Inc. Lignée cellulaire exprimant des polypeptides du facteur viii à chaîne unique et ses utilisations
PT2882450T (pt) 2012-07-11 2020-02-19 Bioverativ Therapeutics Inc Complexo de fator viii com xten e a proteína fator de von willebrand, e utilizações do mesmo
TWI810729B (zh) 2012-09-25 2023-08-01 美商百歐維拉提夫治療公司 Fix多肽的應用
EP2738180A1 (fr) 2012-11-30 2014-06-04 Molecular Partners AG Protéines de liaison comportant au moins deux domaines de liaison ciblant HER2
AU2014228938B2 (en) 2013-03-15 2019-05-02 Bioverativ Therapeutics Inc. Factor IX polypeptide formulations
WO2015022326A1 (fr) 2013-08-12 2015-02-19 Xiber Science Gmbh Peptides en tant qu'agents actifs pour le traitement d'un dysfonctionnement du greffon primaire
TW202003554A (zh) 2013-08-14 2020-01-16 美商百歐維拉提夫治療公司 因子viii-xten融合物及其用途
US20150126458A1 (en) 2013-11-05 2015-05-07 Allergan, Inc. Method of treating conditions of the eye with an anti-vegf darpin
WO2015070014A1 (fr) 2013-11-08 2015-05-14 Biogen Idec Ma Inc. Composé de fusion procoagulant
SI3091997T1 (sl) 2014-01-10 2022-10-28 Bioverativ Therapeutics Inc. Himerni proteini faktorja VIII in njihova uporaba
CN113248623A (zh) 2014-06-18 2021-08-13 阿尔伯特爱因斯坦医学院 Syntac多肽及其用途
WO2016065052A1 (fr) 2014-10-22 2016-04-28 Extend Biosciences, Inc. Conjugués insuline vitamine d
US9585934B2 (en) 2014-10-22 2017-03-07 Extend Biosciences, Inc. Therapeutic vitamin D conjugates
US9789197B2 (en) 2014-10-22 2017-10-17 Extend Biosciences, Inc. RNAi vitamin D conjugates
BR112017020986A2 (pt) 2015-04-02 2018-08-14 Molecular Partners Ag. proteínas de ligação recombinantes e seu uso
JP6983075B2 (ja) 2015-06-02 2021-12-17 ノヴォ ノルディスク アー/エス 極性の組換え延長部を有するインスリン
CA2989400A1 (fr) 2015-06-15 2016-12-22 Angiochem Inc. Ang1005 pour le traitement de la carcinomatose leptomeningee
JP6909203B2 (ja) 2015-08-03 2021-07-28 バイオベラティブ セラピューティクス インコーポレイテッド 第ix因子融合タンパク質及びそれらの製造方法及び使用方法
WO2017040344A2 (fr) 2015-08-28 2017-03-09 Amunix Operating Inc. Ensemble de polypeptides chimériques et procédés de préparation et d'utilisation de ceux-ci
MA43348A (fr) 2015-10-01 2018-08-08 Novo Nordisk As Conjugués de protéines
US11505591B2 (en) 2016-05-18 2022-11-22 Cue Biopharma, Inc. T-cell modulatory multimeric polypeptides and methods of use thereof
US11339201B2 (en) 2016-05-18 2022-05-24 Albert Einstein College Of Medicine Variant PD-L1 polypeptides, T-cell modulatory multimeric polypeptides, and methods of use thereof
CN116970060A (zh) 2016-12-22 2023-10-31 库尔生物制药有限公司 T细胞调节性多聚体多肽及其使用方法
US11851471B2 (en) 2017-01-09 2023-12-26 Cue Biopharma, Inc. T-cell modulatory multimeric polypeptides and methods of use thereof
WO2018185131A2 (fr) 2017-04-05 2018-10-11 Novo Nordisk A/S Conjugués insuline-fc à extension oligomère
KR20200064085A (ko) 2017-09-07 2020-06-05 큐 바이오파마, 인크. 접합 부위를 갖는 t-세포 조절 다량체 폴리펩타이드 및 이의 사용 방법
EP3737689A4 (fr) 2018-01-09 2021-12-01 Cue Biopharma, Inc. Polypeptides multimères modulateurs de lymphocytes t et leurs procédés d'utilisation
WO2019201855A1 (fr) * 2018-04-16 2019-10-24 Swedish Orphan Biovitrum Ab (Publ) Protéine de fusion lysosomale
TW202039542A (zh) 2018-12-19 2020-11-01 美商庫爾生物製藥有限公司 多聚體t細胞調節多肽及其使用方法
WO2020181062A1 (fr) 2019-03-06 2020-09-10 Cue Biopharma, Inc. Polypeptides multimères modulateurs des lymphocytes t et leurs méthodes d'utilisation
JP2023538533A (ja) 2020-08-07 2023-09-08 ブリストル-マイヤーズ スクイブ カンパニー 線維症の処置のための、ccr2/5拮抗剤と組み合わせたfgf21
EP4222176A4 (fr) 2020-09-30 2024-02-28 Beijing Ql Biopharmaceutical Co Ltd Conjugués polypeptidiques et leurs procédés d'utilisation
WO2022115597A1 (fr) 2020-11-25 2022-06-02 Bristol-Myers Squibb Company Méthodes de traitement de maladies du foie
US20240018265A1 (en) 2020-12-11 2024-01-18 Friedrich Miescher Institute For Biomedical Research Hdac6 binding proteins and their anti-viral use
CN115083016A (zh) * 2022-06-09 2022-09-20 广州紫为云科技有限公司 一种基于单目摄像机的面向小目标手部隔空交互方法与装置

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD257197A1 (de) 1987-01-28 1988-06-08 Univ Dresden Tech Verfahren zur herstellung von immobilisierten, in ihrer biologischen aktivitaet stabilisierten und in ihren pharmakologischen eigenschaften modifizierten insulinpraeparationen
FR2647677B1 (fr) * 1989-05-31 1991-09-27 Roussel Uclaf Nouvelles micro-proteines, procede de preparation et application a titre de medicaments de ces nouvelles micro-proteines
RU2114119C1 (ru) 1990-12-13 1998-06-27 Дзе Апджон Компани Слитой белок и способ выделения слитого белка
US5833911A (en) 1995-05-31 1998-11-10 Johnson & Johnson Medical, Inc. Method for forming a glove using a folded glove form
AU5065198A (en) 1996-11-15 1998-06-10 Maria Grazia Masucci Fusion proteins having increased half-lives
EP1054973A1 (fr) * 1998-02-11 2000-11-29 Maxygen, Inc. Immunisation par bibliotheque d'antigenes
US20050260605A1 (en) * 1998-02-11 2005-11-24 Maxygen, Inc. Targeting of genetic vaccine vectors
US20050287153A1 (en) 2002-06-28 2005-12-29 Genentech, Inc. Serum albumin binding peptides for tumor targeting
US20030049689A1 (en) * 2000-12-14 2003-03-13 Cynthia Edwards Multifunctional polypeptides
US20020169125A1 (en) * 2001-03-21 2002-11-14 Cell Therapeutics, Inc. Recombinant production of polyanionic polymers and uses thereof
JP5735194B2 (ja) * 2005-01-25 2015-06-17 セル セラピューティクス インコーポレーテッド 改善された生体内半減期を有する生物学的に活性なタンパク質
US8334257B2 (en) 2005-12-20 2012-12-18 Duke University Methods and compositions for delivering active agents with enhanced pharmacological properties
SI2402754T2 (sl) 2006-03-06 2023-09-29 Amunix Operating Inc. Nestrukturirani rekombinantni polimeri in njihove uporabe
WO2008049711A1 (fr) 2006-10-27 2008-05-02 Novo Nordisk A/S Insuline à peptide ajouté

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
BULAJ GRZEGORZ ET AL: "Efficient oxidative folding of conotoxins and the radiation of venomous cone snails.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 100, no. Supplement 2, 25 November 2003 (2003-11-25), pages 14562 - 14568, XP002515375, ISSN: 0027-8424 *
CHEN X J ET AL: "Site-directed mutations in a highly conserved region of Bacillus thuringiensis delta-endotoxin affect inhibition of short circuit current across Bombyx mori midguts.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 1 OCT 1993, vol. 90, no. 19, 1 October 1993 (1993-10-01), pages 9041 - 9045, XP002515378, ISSN: 0027-8424 *
GOMEZ-DUARTE O G ET AL: "Expression of fragment C of tetanus toxin fused to a carboxyl-terminal fragment of diphtheria toxin in Salmonella typhi CVD 908 vaccine strain", VACCINE, BUTTERWORTH SCIENTIFIC. GUILDFORD, GB, vol. 13, no. 16, 1 November 1995 (1995-11-01), pages 1596 - 1602, XP004057422, ISSN: 0264-410X *
PI C ET AL: "Analysis of expressed sequence tags from the venom ducts of Conus striatus: focusing on the expression profile of conotoxins", BIOCHIMIE, MASSON, PARIS, FR, vol. 88, no. 2, 1 February 2006 (2006-02-01), pages 131 - 140, XP025066514, ISSN: 0300-9084, [retrieved on 20060201] *

Also Published As

Publication number Publication date
EP1996220B2 (fr) 2023-08-16
EP1996220B1 (fr) 2013-05-08
EP1996220A4 (fr) 2009-04-29
AU2007223855A1 (en) 2007-09-13
EP2863222A1 (fr) 2015-04-22
CA2644712C (fr) 2016-09-13
CA2644712A1 (fr) 2007-09-13
SI2402754T1 (sl) 2015-02-27
SI2402754T2 (sl) 2023-09-29
AU2007223888A1 (en) 2007-09-13
WO2007103515A3 (fr) 2008-04-03
DK2402754T3 (en) 2015-01-12
WO2007103515A2 (fr) 2007-09-13
EP1996937A2 (fr) 2008-12-03
WO2007103455A3 (fr) 2007-11-29
AU2007223855B2 (en) 2013-05-16
DK2402754T4 (da) 2023-08-28
EP1996220A2 (fr) 2008-12-03
WO2007103455A2 (fr) 2007-09-13

Similar Documents

Publication Publication Date Title
EP1996937A4 (fr) Materiels génétiques et utilisations correspondantes
ZA200810323B (en) Fkbp-l and uses thereof
ZA200810311B (en) Anti-NKG2A antibodies and uses thereof
LT2064327T (lt) Dbait ir jų panaudojimas
ZA200902823B (en) Oligoribonucleotides and uses thereof
IL196397A0 (en) Prlr-specific antibody and uses thereof
AU313874S (en) Package
IL194751A0 (en) Drugs and uses
GB0621160D0 (en) Compounds and uses thereof
HK1133552A1 (en) Carboranylporphyrins and uses thereof
IL196861A0 (en) Antibodies against ccr5 and uses thereof
IL195525A0 (en) Replikin peptides and uses thereof
IL193469A0 (en) Novel lipases and uses thereof
EP2124908A4 (fr) Composés et utilisations de ceux-ci
GB0604187D0 (en) Peptide and uses thereof
EP2120563A4 (fr) Composés et leurs utilisations
GB0603717D0 (en) Electricity-generate and store
PL2032708T3 (pl) Rekombinowane nowirabdowirusy i ich zastosowania
EP2099459A4 (fr) Composés et leurs utilisations
IL192800A0 (en) Fgf2-binding peptides and uses thereof
EP2120957A4 (fr) Composés et leurs utilisations
GB0621665D0 (en) Blogmail and podmail
GB2444960B (en) Combined pseudoscope and hyperscope
GB0615557D0 (en) Compounds and Uses Thereof
GB0603397D0 (en) Handling extended area articles

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20081006

AK Designated contracting states

Kind code of ref document: A2

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR

A4 Supplementary search report drawn up and despatched

Effective date: 20090305

17Q First examination report despatched

Effective date: 20090717

RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: AMUNIX OPERATING INC.

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20110421