EP1947027A1 - Blister packages and method of temporary storage of products - Google Patents

Blister packages and method of temporary storage of products Download PDF

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Publication number
EP1947027A1
EP1947027A1 EP07100898A EP07100898A EP1947027A1 EP 1947027 A1 EP1947027 A1 EP 1947027A1 EP 07100898 A EP07100898 A EP 07100898A EP 07100898 A EP07100898 A EP 07100898A EP 1947027 A1 EP1947027 A1 EP 1947027A1
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EP
European Patent Office
Prior art keywords
film layer
film
blister pack
pack according
blister
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP07100898A
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German (de)
French (fr)
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EP1947027B1 (en
Inventor
Edwin Kohl
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Individual
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Individual
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Publication date
Priority to AT07100898T priority Critical patent/ATE461876T1/en
Application filed by Individual filed Critical Individual
Priority to EP07100898A priority patent/EP1947027B1/en
Priority to DE502007003215T priority patent/DE502007003215D1/en
Priority to ES07100898T priority patent/ES2340958T3/en
Priority to JP2009546717A priority patent/JP2010516572A/en
Priority to US12/523,985 priority patent/US20100072104A1/en
Priority to PCT/EP2008/050505 priority patent/WO2008090079A1/en
Publication of EP1947027A1 publication Critical patent/EP1947027A1/en
Application granted granted Critical
Publication of EP1947027B1 publication Critical patent/EP1947027B1/en
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D75/00—Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes, or webs of flexible sheet material, e.g. in folded wrappers
    • B65D75/28—Articles or materials wholly enclosed in composite wrappers, i.e. wrappers formed by associating or interconnecting two or more sheets or blanks
    • B65D75/30—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding
    • B65D75/32—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents
    • B65D75/36—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents one sheet or blank being recessed and the other formed of relatively stiff flat sheet material, e.g. blister packages, the recess or recesses being preformed
    • B65D75/367—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents one sheet or blank being recessed and the other formed of relatively stiff flat sheet material, e.g. blister packages, the recess or recesses being preformed and forming several compartments
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B61/00—Auxiliary devices, not otherwise provided for, for operating on sheets, blanks, webs, binding material, containers or packages
    • B65B61/02—Auxiliary devices, not otherwise provided for, for operating on sheets, blanks, webs, binding material, containers or packages for perforating, scoring, slitting, or applying code or date marks on material prior to packaging
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D2575/00—Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes or webs of flexible sheet material, e.g. in folded wrappers
    • B65D2575/28—Articles or materials wholly enclosed in composite wrappers, i.e. wrappers formed by association or interconnecting two or more sheets or blanks
    • B65D2575/30—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding
    • B65D2575/36—One sheet or blank being recessed and the other formed or relatively stiff flat sheet material, e.g. blister packages
    • B65D2575/361—Details
    • B65D2575/362—Details with special means for gaining access to the contents
    • B65D2575/367—Details with special means for gaining access to the contents through a preformed opening in the flat sheet, e.g. the opening being defined by weakened lines

Definitions

  • the invention relates to a blister pack for the temporary storage of products, in particular medicines, and an associated method for the temporary storage of such products in a blister pack.
  • a blister pack for the weekly drug needs of a patient known to take the medication in a order by date, day of the week and time of day (morning, noon and evening and / or night) order.
  • the receiving compartments of the blister pack for receiving the respective medicaments are arranged in matrix form and with seven daily columns, each with at least three time of day compartments, which are closed overall by a continuous blister foil.
  • Affixed to the blister pack is a carton-shaped lid, on which the patient-specific the composition of the individual time of day subjects as well as prescription information concerning the respective medicaments is contained.
  • Such packaging units are for patients who need to take several different medications regularly, a help not only to forget the intake of important drugs and on the other hand to keep a reliable overview of what medications are already taken to avoid a potentially harmful over-medication ,
  • the Strip Blister must therefore have a good seal of the receiving space for the drug especially against water vapor.
  • Such a seal can be achieved for example by an aluminum foil with a minimum thickness of 0.002 mm.
  • this has the disadvantage that when a mechanical force is applied to the medicament unit by the plunger, it does not rupture reliably at the correct location or does not completely rupture, so that errors can occur during the assembly of the weekly blister.
  • the packaging system should be able to process drugs of various sizes and shapes. Since the wrong filling of a compartment of the weekly blister necessarily requires the sorting out of the entire weekly blister, errors in the "repackaging" of the medication from the blister strip in the weekly blister associated with great effort and expense.
  • the US 7,093,716 describes a child-safe blister pack for medicaments with a plurality of receiving compartments, each closed by a foil, which foil has three film layers.
  • the outermost film layer is formed of paperboard material and has tearing sections formed by perforation lines which are difficult to open by small children.
  • a blister pack for the temporary storage of products, in particular medicaments comprising a plurality, each closed by a film receiving compartments for each at least one product unit, which film is formed by a first and a second film layer, wherein the receiving compartments each in the second Foil layer formed perforation sections are assigned, which form a defined tear line of the film upon exertion of a mechanical force on the product unit on the film
  • the first film layer preferably consisting of an air and water vapor impermeable material such as aluminum or plastic allows a secure seal of the drugs even with longer periods.
  • the second film layer preferably consisting of a mechanically rigid material such as paper or cardboard prevents unintentional tearing of the first film layer, so that it can be made comparatively thin.
  • the perforation sections of the second film layer facilitate the preferably mechanical removal of the medicaments from the strip blister. For example, by the plunger of the drug delivery station on the product (drug) a mechanical force on the Product unit applied to the film, so the film tears defined along the Perforationsabterrorisms and allows a reliable transition of the drug unit from the temporary packaging in the delivery package, such as the weekly blister.
  • First and second film layer are preferably glued together, so that a tearing of the aluminum foil during ejection and thus the possibility of falling of film residues is avoided in the weekly blister.
  • the first film layer preferably consisting of an air and water vapor impermeable material such as aluminum or plastic closes, for example, the receiving compartments and the second film layer is formed on the first film layer.
  • the perforation is preferably adapted to the shape and / or size of the product unit received in the receptacle.
  • the first film layer may have, for example, a thickness of 0.002 mm to 0.05 mm and the second film layer may have a thickness of 0.05 mm to 0.5 mm.
  • the depth of the perforation preferably corresponds to the thickness of the second film layer.
  • the second film layer may have on its outside a machine-readable identifier for product identification.
  • the outside of the second film layer is preferably provided with a dark surface. This dark surface also facilitates the attachment of the perforation of the second film layer by means of a controlled laser beam which removes the second film layer (for example consisting of paper material) by thermal action, while the (for example consisting of aluminum) first film layer is not damaged by the laser beam.
  • the blister pack may preferably be formed as an endless strip blister.
  • the invention also proposes a method for the temporary storage of products, in particular medicaments, in a plurality of receiving compartments of a blister pack each closed by a film, which film is formed by a first and a second film layer, comprising the steps of at least mechanically filling the receiving compartments a product unit, sealing the receiving compartments with the film, providing the second film layer with perforation sections in the region of the receiving compartments, which form a defined tear line of the film upon exertion of a mechanical force on the product unit on the film "machine removal of the products from the receiving compartments by exerting a mechanical force over the product unit (30) to the film, the film tearing along the perforation sections.
  • the method step of forming the perforation sections in the second film layer is preferably carried out by means of a laser beam.
  • the method step of the machine removal of the products from the receiving compartments can advantageously be carried out by means of each of the receiving compartments associated, clock-controlled rams.
  • the method step of forming the perforation sections in the second film layer can be carried out, for example, before the method step of mechanically filling the receiving compartments with the products in order to allow the most efficient possible process flow.
  • the production of the perforation sections by means of a laser beam can be flexibly adjusted to different drug sizes and shapes, so that in the method according to the invention several different medicaments can be successively packed into respective endless strip blisters for temporary storage.
  • FIG. 1 shows a schematic side view of a strip blister.
  • FIG. 2 shows an enlarged schematic side view of an embodiment of the blister pack according to the invention.
  • FIG. 3 shows a plan view of the film side of a first embodiment of the blister pack according to the invention.
  • FIG. 4 shows a plan view of the film side of a second embodiment of the blister pack according to the invention.
  • FIG. 5 is a flowchart for explaining the method steps of an embodiment of the method according to the invention.
  • FIG. 1 shows a schematic side view of a strip blister for the temporary storage of products, in particular drugs.
  • the product units are preferably individually filled by machine into the blister pack formed as endless strip blister 20.
  • One filled strip blister per medication type is made available to the weekly blister placement system as a product supply. Since the drugs processed by the assembly system are consumed in very different amounts, comparatively long storage times can occur in the strip blisters.
  • an individually assigned dispensing station is provided for each drug, which conveys the respective medicaments from the endless strip blister into the corresponding receiving compartments of the packaging unit, for example by means of the spatulas of the strip blister.
  • patient-specific weekly blister packs can be filled automatically and safely with a selection of several hundred drugs.
  • the critical step is the "repackaging" of the product units from the strip blister into the weekly blister.
  • the blister pack 20 comprises a closure film 25 consisting of a first film layer 24 and a second film layer 26, wherein the second film layer 26 is provided with perforation sections 28 which remove the product units from the temporary packaging Facilitate blister strips and prevent tearing of the aluminum foil during ejection
  • a first embodiment of the blister pack according to the invention is in FIG. 2 shown.
  • the first film layer 24 preferably consisting of an air and water vapor impermeable material such as aluminum or plastic closes the respective receiving compartments 21 for the product units 30 (shown in phantom) and allows a secure sealing of the drugs even with longer storage times.
  • the second film layer 26 preferably consisting of a mechanically rigid material such as paper or cardboard prevents unintentional tearing of the first film layer in mechanical deformations such as winding and unwinding of the strip blister on the associated supply roll, so that the first film layer 24 itself are formed comparatively thin which helps the product removal process.
  • the perforation section 28 assigned to the respective receiving compartments in the second film layer 26 facilitates the preferably mechanical removal of the medicament units.
  • the second film layer prevents a tearing off of the abraided flap formed from the first film layer.
  • the first and second film layers are glued together, so that the aluminum foil does not tear when ejected and no film residues fall into the weekly blister.
  • the perforation section 28 is preferably adapted to the shape and / or size of the product unit received in the receptacle.
  • Two embodiments of different forms of the perforation 28 are in the FIGS. 3 and 4 shown.
  • the perforation section 28 can be as in Fig. 3 shown consist of a single continuous U-shaped line or as in Fig. 4 shown consist of two separate, complementary Perforationsabêten. Depending on the form of medication, different perforation arrangements are conceivable within the scope of the present invention.
  • the first film layer may have, for example, a thickness of 0.002 mm to 0.05 mm and the second film layer may have a thickness of 0.05 mm to 0.5 mm.
  • the depth of the perforation preferably corresponds to the thickness of the second film layer, but may also have a smaller depth, so that the second film layer 26 is not completely severed.
  • the second film layer 26 may have on its outside a machine-readable identifier 32 for product identification.
  • the perforation 28 is applied to the outer film layer 26, preferably by means of a controlled laser beam, which passes through the second, outer film layer 26 (for example consisting of paper material) thermal exposure removed, while the (for example made of aluminum) first film layer 24 is not damaged by the laser beam.
  • a controlled laser beam which passes through the second, outer film layer 26 (for example consisting of paper material) thermal exposure removed, while the (for example made of aluminum) first film layer 24 is not damaged by the laser beam.
  • this preferably has a dark surface.
  • step S4 the receiving compartments 21 of the strip blister 20 are preferably filled with the product units 30 in a manner known per se.
  • the blister compartments 21 are closed in a manner which is also known per se by applying, for example welding or sealing, the blister foil 25 and thus sealed impermeable to air and water vapor.
  • step S8 a force is exerted on the sealing film 25 by the product units 30 itself so that it tears along the perforation sections 28 of the upper film layer 26 and so reliably and without delay delays the product units 30 from the receiving compartments 21 be removed and in the weekly blister or the like can be repackaged.
  • the formation of the perforation sections by means of a laser beam is flexibly adjustable to different drug sizes and shapes, so that the invention allows the intermediate storage of several different drugs in strip blisters in successive steps on the same system.
  • the invention thus enables the secure temporary storage of products, in particular medicines, even over long periods of time and a reliable, preferably mechanical removal and repackaging of the products in another packaging unit such as a weekly blister.

Abstract

A medical blister pack has a base with a pre-determined number of detents (21) covered by a foil (25) seal. Each detent contains one unit of product (30). The foil has a first inner layer, and a second outer layer (26) incorporating perforation lines (28). On application of a mechanical force on the product the perforation line ruptures to allow mechanical removal of the product from the blister pack (20).

Description

Gebiet der ErfindungField of the invention

Die Erfindung betrifft eine Blisterpackung zur vorübergehenden Lagerung von Produkten, insbesondere Medikamenten, sowie ein zugehöriges Verfahren zur vorübergehenden Lagerung von derartigen Produkten in einer Blisterpackung.The invention relates to a blister pack for the temporary storage of products, in particular medicines, and an associated method for the temporary storage of such products in a blister pack.

Verwandter Stand der TechnikRelated prior art

Aus der DE 10 2004 034 024 A2 ist eine Blisterpackung für den wöchentlichen Medikamentenbedarf eines Patienten bekannt, der die Medikamente in einer nach Datum, Wochentag und Tageszeit (Morgen, Mittag und Abend und/oder Nacht) geordneten Folge einnehmen soll. Die Aufnahmefächer der Blisterpackung zur Aufnahme der jeweiligen Medikamente sind in Matrixform angeordnet und mit sieben Tagesspalten mit jeweils mindestens drei Tageszeit-Fächern, die insgesamt durch eine zusammenhängende Blisterfolie verschlossen sind. An der Blisterpackung angebracht ist ein kartonförmiger Deckel, auf dem patientenindividuell die Zusammensetzung der einzelnen Tageszeit-Fächer sowie Verschreibungsinformationen betreffend die jeweiligen Medikamente enthalten ist.From the DE 10 2004 034 024 A2 is a blister pack for the weekly drug needs of a patient known to take the medication in a order by date, day of the week and time of day (morning, noon and evening and / or night) order. The receiving compartments of the blister pack for receiving the respective medicaments are arranged in matrix form and with seven daily columns, each with at least three time of day compartments, which are closed overall by a continuous blister foil. Affixed to the blister pack is a carton-shaped lid, on which the patient-specific the composition of the individual time of day subjects as well as prescription information concerning the respective medicaments is contained.

Derartige Verpackungseinheiten sind für Patienten, die regelmäßig mehrere verschiedene Medikamente einnehmen müssen, eine Hilfe dafür, einerseits das Einnehmen wichtiger Medikamente nicht zu vergessen und andererseits auch einen zuverlässigen Überblick darüber zu behalten, welche Medikamente schon eingenommen sind, um eine unter Umständen schädliche Übermedikation zu vermeiden.Such packaging units are for patients who need to take several different medications regularly, a help not only to forget the intake of important drugs and on the other hand to keep a reliable overview of what medications are already taken to avoid a potentially harmful over-medication ,

Aus der DE 10 2004 020 510 A1 sowie der WO 2005 102 841 A1 ist eine Anlage zur Bestückung von derartigen Verpackungseinheiten mit der gewünschten Medikamentenzusammenstellung bekannt. Für jedes Medikament ist eine individuell zugeordnete Ausgabestation vorgesehen, die mittels den Aufnahmefächern der Verpackungseinheit räumlich zugeordneten Stößeln die jeweiligen Medikamente aus einer vorübergehenden Verpackung in Form eines Streifenblisters in die entsprechenden Aufnahmefächer der Verpackungseinheit befördert. So können patientenindividuelle Verpackungseinheiten mit einer Auswahl aus mehreren hundert Medikamenten vollautomatisch sicher und zuverlässig befüllt werden.From the DE 10 2004 020 510 A1 as well as the WO 2005 102 841 A1 is a system for equipping such packaging units with the desired drug composition known. For each drug, an individually assigned dispensing station is provided, which conveys the respective medicaments from a temporary package in the form of a strip blister into the corresponding receiving compartments of the packaging unit by means of the receiving compartments of the packaging unit spatially associated plungers. In this way, patient-specific packaging units can be filled automatically and safely with a selection of several hundred drugs.

Da die von der Verpackungsanlage verarbeiteten Medikamente in sehr unterschiedlichen Mengen verschrieben werden, können bei den seltener verschriebenen Medikamenten relativ lange "Standzeiten" in den vorübergehenden Verpackungen, d.h. den Streifenblistern auftreten. Damit die Medikamente nicht durch das Eindringen von Feuchtigkeit oder dgl. unbrauchbar werden, muß der Streifenblister daher eine gute Versiegelung des Aufnahmeraumes für das Medikament insbesondere gegenüber Wasserdampf aufweisen. Eine solche Versiegelung kann beispielsweise durch eine Aluminiumfolie mit einer Mindestdicke von 0,002 mm erreicht werden. Diese hat andererseits den Nachteil, dass sie bei Anwendung einer mechanischen Kraft auf die Medikamenteneinheit durch den Stößel nicht zuverlässig an der richtigen Stelle oder nicht vollständig aufreißt, so dass es zu Fehlern bei der Bestückung der Wochenblister kommen kann. Es gilt weiterhin, ein Abreissen der Aluminiumfolie beim Ausstossen und damit die Möglichkeit des Hineinfallens von Folienresten in den Wochenblister zu verhindern. Außerdem sollte die Verpackungsanlage Medikamente verschiedenster Größen und Formen bearbeiten können. Da schon die falsche Befüllung eines Faches des Wochenblisters zwingend die Aussortierung des gesamten Wochenblisters bedingt, sind Fehler bei der "Umpackung" der Medikamente aus dem Streifenblister in den Wochenblister mit hohem Aufwand und Kosten verbunden.Since the drugs processed by the packaging equipment are prescribed in very different amounts, the more rarely prescribed drugs can have relatively long "lives" in the temporary packaging, i. the strip blisters occur. Thus, the drugs are not unusable by the ingress of moisture or the like., The Strip Blister must therefore have a good seal of the receiving space for the drug especially against water vapor. Such a seal can be achieved for example by an aluminum foil with a minimum thickness of 0.002 mm. On the other hand, this has the disadvantage that when a mechanical force is applied to the medicament unit by the plunger, it does not rupture reliably at the correct location or does not completely rupture, so that errors can occur during the assembly of the weekly blister. It also applies to prevent tearing of the aluminum foil during ejection and thus the possibility of falling film residues in the Wochenblister. In addition, the packaging system should be able to process drugs of various sizes and shapes. Since the wrong filling of a compartment of the weekly blister necessarily requires the sorting out of the entire weekly blister, errors in the "repackaging" of the medication from the blister strip in the weekly blister associated with great effort and expense.

Die US 7,093,716 beschreibt eine kindersichere Blisterpackung für Medikamente mit mehreren, jeweils durch eine Folie verschlossenen Aufnahmefächern, welche Folie drei Folienschichten aufweist. Die äußerste Folienschicht ist aus Kartonmaterial ausgebildet und weist durch Perforationslinien gebildete Aufreißabschnitte auf, die durch kleine Kinder schwer zu öffnen sind.The US 7,093,716 describes a child-safe blister pack for medicaments with a plurality of receiving compartments, each closed by a foil, which foil has three film layers. The outermost film layer is formed of paperboard material and has tearing sections formed by perforation lines which are difficult to open by small children.

Zusammenfassung der ErfindungSummary of the invention

Es ist daher eine Aufgabe der Erfindung, eine Blisterpackung zur vorübergehenden Lagerung von Produkten, insbesondere Medikamenten, sowie ein zugehöriges Verfahren zur vorübergehenden Lagerung von derartigen Produkten in einer Blisterpackung vorzuschlagen, die die oben beschriebenen Probleme löst und lange Zwischenlagerungszeiten und gleichzeitig einen sicheren Transfer der Produkteinheiten in die auszuliefernde Verpackungseinheit (Wochenblister) erlaubt.It is therefore an object of the invention to propose a blister pack for the temporary storage of products, in particular medicines, and an associated method for the temporary storage of such products in a blister pack, which solves the problems described above and long storage times and at the same time a secure transfer of product units in the delivered packaging unit (weekly blister) allowed.

Gelöst wird die Aufgabe durch eine Blisterpackung zur vorübergehenden Lagerung von Produkten, insbesondere Medikamenten, aufweisend mehrere, jeweils durch eine Folie verschlossene Aufnahmefächer für jeweils wenigstens eine Produkteinheit, welche Folie gebildet ist durch eine erste und eine zweite Folienschicht, wobei den Aufnahmefächern jeweils in der zweiten Folienschicht ausgebildete Perforationsabschnitte zugeordnet sind, die bei Ausübung einer mechanischen Kraft über die Produkteinheit auf die Folie eine definierte Aufreißlinie der Folie bildenThe object is achieved by a blister pack for the temporary storage of products, in particular medicaments, comprising a plurality, each closed by a film receiving compartments for each at least one product unit, which film is formed by a first and a second film layer, wherein the receiving compartments each in the second Foil layer formed perforation sections are assigned, which form a defined tear line of the film upon exertion of a mechanical force on the product unit on the film

Die erste Folienschicht vorzugsweise bestehend aus einem luft- und wasserdampfundurchlässigen Material wie beispielsweise Aluminium oder Kunststoff ermöglicht eine sichere Versiegelung der Medikamente auch bei längeren Standzeiten. Die zweite Folienschicht vorzugsweise bestehend aus einem mechanisch steifen Material wie beispielsweise Papier oder Karton verhindert ein unbeabsichtigtes Aufreißen der ersten Folienschicht, so dass diese vergleichsweise dünn ausgebildet werden kann. Die Perforationsabschnitte der zweiten Folienschicht erleichtern die vorzugsweise maschinelle Entnahme der Medikamente aus dem Streifenblister. Wird beispielsweise durch den Stößel der Medikamenten-Ausgabestation über das Produkt (Medikament) eine mechanische Kraft über die Produkteinheit auf die Folie ausgeübt, so reißt die Folie definiert entlang des Perforationsabschnitts ein und ermöglicht einen zuverlässigen Übergang der Medikamenteneinheit aus der vorübergehenden Verpackung in die Auslieferungsverpackung, etwa den Wochenblister.The first film layer, preferably consisting of an air and water vapor impermeable material such as aluminum or plastic allows a secure seal of the drugs even with longer periods. The second film layer preferably consisting of a mechanically rigid material such as paper or cardboard prevents unintentional tearing of the first film layer, so that it can be made comparatively thin. The perforation sections of the second film layer facilitate the preferably mechanical removal of the medicaments from the strip blister. For example, by the plunger of the drug delivery station on the product (drug) a mechanical force on the Product unit applied to the film, so the film tears defined along the Perforationsabschnitts and allows a reliable transition of the drug unit from the temporary packaging in the delivery package, such as the weekly blister.

Erste und zweite Folienschicht sind vorzugsweise miteinander verklebt, so dass ein Abreissen der Aluminiumfolie beim Ausstoßen und damit die Möglichkeit des Hineinfallens von Folienresten in den Wochenblister vermieden wird.First and second film layer are preferably glued together, so that a tearing of the aluminum foil during ejection and thus the possibility of falling of film residues is avoided in the weekly blister.

Die erste Folienschicht vorzugsweise bestehend aus einem luft- und wasserdampfundurchlässigen Material wie beispielsweise Aluminium oder Kunststoff verschließt dabei beispielsweise die Aufnahmefächer und die zweite Folienschicht ist auf der ersten Folienschicht ausgebildet.The first film layer preferably consisting of an air and water vapor impermeable material such as aluminum or plastic closes, for example, the receiving compartments and the second film layer is formed on the first film layer.

Um die Entfernung der Produkteinheiten aus der Blisterpackung weiter zu vereinfachen, ist die Perforation vorzugsweise an die Form und/oder Größe der in dem Aufnahmefach aufgenommenen Produkteinheit angepaßt.To further facilitate the removal of the product units from the blister pack, the perforation is preferably adapted to the shape and / or size of the product unit received in the receptacle.

Die erste Folienschicht kann dabei beispielsweise eine Dicke von 0,002 mm bis 0,05 mm und die zweite Folienschicht eine Dicke von 0,05 mm bis 0,5 mm aufweisen. Die Tiefe der Perforation entspricht dabei vorzugsweise der Dicke der zweiten Folienschicht.The first film layer may have, for example, a thickness of 0.002 mm to 0.05 mm and the second film layer may have a thickness of 0.05 mm to 0.5 mm. The depth of the perforation preferably corresponds to the thickness of the second film layer.

Die zweite Folienschicht kann auf ihrer Außenseite eine maschinenlesbare Kennung zur Produktidentifizierung aufweisen. Um eine gute Lesbarkeit dieser Kennung zu gewährleisten, ist die Außenseite der zweiten Folienschicht vorzugsweise mit einer dunklen Oberfläche versehen. Diese dunkle Oberfläche erleichtert auch das Anbringen der Perforation der zweiten Folienschicht mittels eines gesteuerten Laserstrahls, der die zweite Folienschicht (beispielsweise bestehend aus Papiermaterial) durch thermische Einwirkung entfernt, während die (beispielsweise aus Aluminium bestehende) erste Folienschicht durch den Laserstrahl nicht beschädigt wird.The second film layer may have on its outside a machine-readable identifier for product identification. In order to ensure good readability of this identifier, the outside of the second film layer is preferably provided with a dark surface. This dark surface also facilitates the attachment of the perforation of the second film layer by means of a controlled laser beam which removes the second film layer (for example consisting of paper material) by thermal action, while the (for example consisting of aluminum) first film layer is not damaged by the laser beam.

Die Blisterpackung kann vorzugsweise als Endlos-Streifenblister ausgebildet sein.The blister pack may preferably be formed as an endless strip blister.

Die Erfindung schlägt außerdem ein Verfahren zur vorübergehenden Lagerung von Produkten, insbesondere Medikamenten, in mehreren, jeweils durch eine Folie verschlossenen Aufnahmefächern einer Blisterpackung vor, welche Folie durch eine erste und eine zweite Folienschicht gebildet ist, aufweisend die Schritte maschinelles Befüllen der Aufnahmefächer mit jeweils wenigstens einer Produkteinheit, Verschließen der Aufnahmefächer mit der Folie, Versehen der zweiten Folienschicht mit Perforationsabschnitten im Bereich der Aufnahmefächer, die bei Ausübung einer mechanischen Kraft über die Produkteinheit auf die Folie eine definierte Aufreißlinie der Folie bilden" maschinelle Entnahme der Produkte aus den Aufnahmefächern durch Ausüben einer mechanischen Kraft über die Produkteinheit (30) auf die Folie, wobei die Folie entlang der Perforationsabschnitte aufreißt.The invention also proposes a method for the temporary storage of products, in particular medicaments, in a plurality of receiving compartments of a blister pack each closed by a film, which film is formed by a first and a second film layer, comprising the steps of at least mechanically filling the receiving compartments a product unit, sealing the receiving compartments with the film, providing the second film layer with perforation sections in the region of the receiving compartments, which form a defined tear line of the film upon exertion of a mechanical force on the product unit on the film "machine removal of the products from the receiving compartments by exerting a mechanical force over the product unit (30) to the film, the film tearing along the perforation sections.

Wie oben erläutert wird der Verfahrensschritt der Bildung der Perforationsabschnitte in der zweiten Folienschicht vorzugsweise mittels eines Laserstrahls durchgeführt.As explained above, the method step of forming the perforation sections in the second film layer is preferably carried out by means of a laser beam.

Der Verfahrensschritt der maschinellen Entnahme der Produkte aus den Aufnahmefächern kann vorteilhaft mittels jedem der Aufnahmefächer zugeordneten, taktgesteuerten Stößeln durchgeführt werden.The method step of the machine removal of the products from the receiving compartments can advantageously be carried out by means of each of the receiving compartments associated, clock-controlled rams.

Der Verfahrensschritt der Bildung der Perforationsabschnitte in der zweiten Folienschicht kann beispielsweise vor dem Verfahrensschritt des maschinellen Befüllens der Aufnahmefächer mit den Produkten ausgeführt werden, um einen möglichst rationellen Verfahrensablauf zu ermöglichen.The method step of forming the perforation sections in the second film layer can be carried out, for example, before the method step of mechanically filling the receiving compartments with the products in order to allow the most efficient possible process flow.

Die Herstellung der Perforationsabschnitte mittels Laserstrahl ist flexibel auf unterschiedliche Medikamentengrößen und -formen einstellbar, so dass bei dem erfindungsgemäßen Verfahren nacheinander mehrere verschiedene Medikamente in jeweilige Endlos-Streifenblister zur vorübergehenden Lagerung abgepackt werden können.The production of the perforation sections by means of a laser beam can be flexibly adjusted to different drug sizes and shapes, so that in the method according to the invention several different medicaments can be successively packed into respective endless strip blisters for temporary storage.

Kurze Beschreibung der ZeichnungenBrief description of the drawings

Die Erfindung wird im folgenden anhand von Ausführungsbeispielen unter Bezugnahme auf die Zeichnungen im Detail beschrieben.The invention will be described below in detail with reference to embodiments with reference to the drawings.

Figur 1 zeigt eine schematische Seitenansicht eines Streifenblisters. FIG. 1 shows a schematic side view of a strip blister.

Figur 2 zeigt eine vergrößerte schematische Seitenansicht eines Ausführungsbeispiels der erfindungsgemäßen Blisterpackung. FIG. 2 shows an enlarged schematic side view of an embodiment of the blister pack according to the invention.

Figur 3 zeigt eine Aufsicht auf die Folienseite eines ersten Ausführungsbeispiels der erfindungsgemäßen Blisterpackung. FIG. 3 shows a plan view of the film side of a first embodiment of the blister pack according to the invention.

Figur 4 zeigt eine Aufsicht auf die Folienseite eines zweiten Ausführungsbeispiels der erfindungsgemäßen Blisterpackung. FIG. 4 shows a plan view of the film side of a second embodiment of the blister pack according to the invention.

Figur 5 ist ein Flussdiagramm zur Erläuterung der Verfahrensschritte eines Ausführungsbeispiels des erfindungsgemäßen Verfahrens. FIG. 5 is a flowchart for explaining the method steps of an embodiment of the method according to the invention.

Detaillierte Beschreibung der ErfindungDetailed description of the invention

Figur 1 zeigt eine schematische Seitenansicht eines Streifenblisters zur vorübergehenden Lagerung von Produkten, insbesondere Medikamenten. Die Produkteinheiten werden vorzugsweise maschinell einzeln in die als Endlos-Streifenblister 20 ausgebildete Blisterpackung eingefüllt. Je ein gefüllter Streifenblister je Medikamentensorte wird der Wochenblister-Bestückungsanlage als Produktvorrat zur Verfügung gestellt. Da die von der Bestückungsanlage verarbeiteten Medikamente in sehr unterschiedlichen Mengen verbraucht werden, können vergleichsweise lange Lagerungszeiten in den Streifenblistern auftreten. FIG. 1 shows a schematic side view of a strip blister for the temporary storage of products, in particular drugs. The product units are preferably individually filled by machine into the blister pack formed as endless strip blister 20. One filled strip blister per medication type is made available to the weekly blister placement system as a product supply. Since the drugs processed by the assembly system are consumed in very different amounts, comparatively long storage times can occur in the strip blisters.

In der Wochenblister-Bestückungsanlage ist für jedes Medikament eine individuell zugeordnete Ausgabestation vorgesehen, die beispielsweise mittels den Aufnahmefächern des Streifenblisters räumlich zugeordneten Stößeln die jeweiligen Medikamente aus dem Endlos-Streifenblister in die entsprechenden Aufnahmefächer der Verpackungseinheit befördert. So können patientenindividuelle Wochenblister mit einer Auswahl aus mehreren hundert Medikamenten vollautomatisch sicher und zuverlässig befüllt werden. Der kritische Arbeitsschritt ist dabei die "Umverpackung" der Produkteinheiten aus dem Streifenblister in den Wochenblister.In the weekly blister placement system, an individually assigned dispensing station is provided for each drug, which conveys the respective medicaments from the endless strip blister into the corresponding receiving compartments of the packaging unit, for example by means of the spatulas of the strip blister. Thus, patient-specific weekly blister packs can be filled automatically and safely with a selection of several hundred drugs. The critical step is the "repackaging" of the product units from the strip blister into the weekly blister.

Um diesen kritischen Arbeitsschritt zu erleichtern, weist die erfindungsgemäße Blisterpackung 20 eine Verschlussfolie 25 bestehend aus einer ersten Folienschicht 24 und einer zweiten Folienschicht 26 auf, wobei die zweite Folienschicht 26 mit Perforationsabschnitten 28 versehen ist, die eine Entnahme der Produkteinheiten aus dem als vorübergehende Verpackung dienenden Streifenblister erleichtern und ein Abreißen der Aluminiumfolie beim Ausstoßen verhindernIn order to facilitate this critical operation, the blister pack 20 according to the invention comprises a closure film 25 consisting of a first film layer 24 and a second film layer 26, wherein the second film layer 26 is provided with perforation sections 28 which remove the product units from the temporary packaging Facilitate blister strips and prevent tearing of the aluminum foil during ejection

Ein erstes Ausführungsbeispiel der erfindungsgemäßen Blisterpackung ist in Figur 2 dargestellt. Die erste Folienschicht 24 vorzugsweise bestehend aus einem luft- und wasserdampfundurchlässigen Material wie beispielsweise Aluminium oder Kunststoff verschließt die jeweiligen Aufnahmefächer 21 für die Produkteinheiten 30 (gestrichelt dargestellt) und ermöglicht eine sichere Versiegelung der Medikamente auch bei längeren Lagerzeiten. Die zweite Folienschicht 26 vorzugsweise bestehend aus einem mechanisch steifen Material wie beispielsweise Papier oder Karton verhindert ein unbeabsichtigtes Aufreißen der ersten Folienschicht bei mechanischen Verformungen etwa beim Auf- und Abwickeln des Streifenblisters auf die zugehörige Vorratsrolle, so dass die erste Folienschicht 24 selbst vergleichsweise dünn ausgebildet werden kann, wodurch der Produktentnahmevorgang unterstützt wird. Weiterhin erleichtert der den jeweiligen Aufnahmefächern zugeordnete Perforationsabschnitt 28 in der zweiten Folienschicht 26 die vorzugsweise maschinelle Entnahme der Medikamenteneinheiten. Wird beispielsweise durch den Stößel der Medikamenten-Ausgabestation über die Produkteinheit 30 eine mechanische Kraft auf die Folie 25 ausgeübt, so reißt die Folie definiert entlang des Perforationsabschnitts 28 ein und ermöglicht eine zuverlässige Entfernung des Produktes 30 aus der Streifenblisterpackung 20 durch die in der Folie entlang der Perforation definiert gebildete Öffnung. Dabei verhindert die zweite Folienschicht ein Abreissen der aus der ersten Folienschicht gebildeten aufgestossenen Lasche. Die erste und zweite Folienschicht sind miteinander verklebt, so dass die Aluminiumfolie beim Ausstoßen nicht abreißt und keine Folienreste in den Wochenblister fallen.A first embodiment of the blister pack according to the invention is in FIG. 2 shown. The first film layer 24 preferably consisting of an air and water vapor impermeable material such as aluminum or plastic closes the respective receiving compartments 21 for the product units 30 (shown in phantom) and allows a secure sealing of the drugs even with longer storage times. The second film layer 26 preferably consisting of a mechanically rigid material such as paper or cardboard prevents unintentional tearing of the first film layer in mechanical deformations such as winding and unwinding of the strip blister on the associated supply roll, so that the first film layer 24 itself are formed comparatively thin which helps the product removal process. Furthermore, the perforation section 28 assigned to the respective receiving compartments in the second film layer 26 facilitates the preferably mechanical removal of the medicament units. If, for example, a mechanical force is exerted on the film 25 by the plunger of the medicament dispensing station via the product unit 30, then the film tears along the length of the film Perforation section 28 and allows a reliable removal of the product 30 from the blister pack 20 by the opening formed in the film defined along the perforation. In this case, the second film layer prevents a tearing off of the abraided flap formed from the first film layer. The first and second film layers are glued together, so that the aluminum foil does not tear when ejected and no film residues fall into the weekly blister.

Um die Entfernung der Produkteinheiten 30 aus der Blisterpackung 20 weiter zu optimieren, ist der Perforationsabschnitt 28 vorzugsweise an die Form und/oder Größe der in dem Aufnahmefach aufgenommenen Produkteinheit angepaßt. Zwei Ausführungsbeispiele unterschiedlicher Formen der Perforation 28 sind in den Figuren 3 und 4 dargestellt. Der Perforationsabschnitt 28 kann dabei wie in Fig. 3 gezeigt aus einer einzigen zusammenhängenden U-förmigen Linie bestehen oder wie in Fig. 4 gezeigt aus zwei separaten, sich ergänzenden Perforationsabschnitten bestehen. Je nach Medikamentenform sind verschiedene Perforationsanordnungen im Rahmen der vorliegenden Erfindung denkbar.In order to further optimize the removal of the product units 30 from the blister pack 20, the perforation section 28 is preferably adapted to the shape and / or size of the product unit received in the receptacle. Two embodiments of different forms of the perforation 28 are in the FIGS. 3 and 4 shown. The perforation section 28 can be as in Fig. 3 shown consist of a single continuous U-shaped line or as in Fig. 4 shown consist of two separate, complementary Perforationsabschnitten. Depending on the form of medication, different perforation arrangements are conceivable within the scope of the present invention.

Die erste Folienschicht kann dabei beispielsweise eine Dicke von 0,002 mm bis 0,05 mm und die zweite Folienschicht eine Dicke von 0,05 mm bis 0,5 mm aufweisen. Die Tiefe der Perforation entspricht dabei vorzugsweise der Dicke der zweiten Folienschicht, kann jedoch auch eine geringere Tiefe aufweisen, so dass die zweite Folienschicht 26 nicht vollständig durchtrennt wird.The first film layer may have, for example, a thickness of 0.002 mm to 0.05 mm and the second film layer may have a thickness of 0.05 mm to 0.5 mm. The depth of the perforation preferably corresponds to the thickness of the second film layer, but may also have a smaller depth, so that the second film layer 26 is not completely severed.

Wie in Fig. 4 gezeigt kann die zweite Folienschicht 26 auf ihrer Außenseite eine maschinenlesbare Kennung 32 zur Produktidentifizierung aufweisen.As in Fig. 4 As shown, the second film layer 26 may have on its outside a machine-readable identifier 32 for product identification.

Ein Ausführungsbeispiel des erfindungsgemäßen Verfahrens wird im Folgenden anhand des Flußdiagramms von Fig. 5 erläutert.An embodiment of the method according to the invention is described below with reference to the flowchart of Fig. 5 explained.

Im ersten Verfahrensschritt S2 wird die Perforierung 28 auf die äußere Folienschicht 26 vorzugsweise mittels eines gesteuerten Laserstrahls aufgebracht, der die zweite, äußere Folienschicht 26 (beispielsweise bestehend aus Papiermaterial) durch thermische Einwirkung entfernt, während die (beispielsweise aus Aluminium bestehende) erste Folienschicht 24 durch den Laserstrahl nicht beschädigt wird. Um die thermische Entfernung der zweiten Folienschicht 26 mittels Laserstrahl zu unterstützen, weist diese vorzugsweise eine dunkle Oberfläche auf.In the first method step S2, the perforation 28 is applied to the outer film layer 26, preferably by means of a controlled laser beam, which passes through the second, outer film layer 26 (for example consisting of paper material) thermal exposure removed, while the (for example made of aluminum) first film layer 24 is not damaged by the laser beam. In order to assist the thermal removal of the second film layer 26 by means of a laser beam, this preferably has a dark surface.

Im folgenden Verfahrensschritt S4 werden die Aufnahmefächer 21 des Streifenblisters 20 auf an sich bekannte Art und Weise vorzugsweise maschinell mit den Produkteinheiten 30 befüllt.In the following method step S4, the receiving compartments 21 of the strip blister 20 are preferably filled with the product units 30 in a manner known per se.

Im anschließenden Verfahrensschritt S6 werden die Blisterfächer 21 auf ebenfalls an sich bekannte Art und Weise durch Aufbringen, beispielsweise Verschweißen oder Versiegeln der Blisterfolie 25 verschlossen und damit luft- und wasserdampfundurchlässig versiegelt.In the subsequent method step S6, the blister compartments 21 are closed in a manner which is also known per se by applying, for example welding or sealing, the blister foil 25 and thus sealed impermeable to air and water vapor.

Im abschließenden Verfahrensschritt S8 schließlich wird mittels der oben beschriebenen Stößel durch die Produkteinheiten 30 selbst eine Kraftwirkung auf die Verschlussfolie 25 ausgeübt, so dass diese entlang der Perforationsabschnitte 28 der oberen Folienschicht 26 definiert aufreißt und so die Produkteinheiten 30 zuverlässig und ohne Verzögerung aus den Aufnahmefächern 21 entfernt werden und in die Wochenblister oder dgl. umgepackt werden können. Die Bildung der Perforationsabschnitte mittels Laserstrahl ist flexibel auf unterschiedliche Medikamentengrößen und -formen einstellbar, so dass die Erfindung die Zwischenlagerung mehrerer verschiedener Medikamente in Streifenblistern in aufeinanderfolgenden Arbeitsschritten auf derselben Anlage erlaubt.Finally, in the concluding method step S8, a force is exerted on the sealing film 25 by the product units 30 itself so that it tears along the perforation sections 28 of the upper film layer 26 and so reliably and without delay delays the product units 30 from the receiving compartments 21 be removed and in the weekly blister or the like can be repackaged. The formation of the perforation sections by means of a laser beam is flexibly adjustable to different drug sizes and shapes, so that the invention allows the intermediate storage of several different drugs in strip blisters in successive steps on the same system.

Die Erfindung ermöglicht so die sichere vorübergehenden Lagerung von Produkten, insbesondere Medikamenten, auch über längere Zeiträume sowie eine zuverlässige, vorzugsweise maschinelle Entnahme und Neuverpackung der Produkte in eine andere Verpackungseinheit wie etwa einen Wochenblister.The invention thus enables the secure temporary storage of products, in particular medicines, even over long periods of time and a reliable, preferably mechanical removal and repackaging of the products in another packaging unit such as a weekly blister.

Claims (21)

Blisterpackung zur vorübergehenden Lagerung von Produkten, insbesondere Medikamenten, aufweisend mehrere, jeweils durch eine Folie (25) verschlossene Aufnahmefächer (21) für jeweils wenigstens eine Produkteinheit (30), welche Folie (25) gebildet ist durch eine erste und eine zweite Folienschicht, wobei den Aufnahmefächern (21) jeweils in der zweiten Folienschicht (26) ausgebildete Perforationsabschnitte (28) zugeordnet sind, die bei Ausübung einer mechanischen Kraft über die Produkteinheit (30) auf die Folie (25) eine definierte Aufreißlinie der Folie (25) bilden.Blister pack for the temporary storage of products, in particular medicaments, comprising a plurality of receiving compartments (21) each closed by a film (25) for at least one product unit (30), which film (25) is formed by a first and a second film layer, wherein the perforation sections (28) formed in each case in the second film layer (26) are associated with the receiving compartments (21) and form a defined tear line of the film (25) on the film (25) when a mechanical force is exerted on the product unit (30). Blisterpackung nach Anspruch 1, wobei die erste Folienschicht (24) die Aufnahmefächer (21) verschließt und die zweite Folienschicht (26) auf der ersten Folienschicht (24) ausgebildet ist.Blister pack according to claim 1, wherein the first film layer (24) closes the receiving compartments (21) and the second film layer (26) is formed on the first film layer (24). Blisterpackung nach Anspruch 1 oder 2, wobei die Perforationsabschnitte (28) an die Form und/oder Größe der in dem Aufnahmefach (21) aufgenommenen Produkteinheit (30) angepaßt ist.Blister pack according to claim 1 or 2, wherein the perforation sections (28) are adapted to the shape and / or size of the product unit (30) accommodated in the receptacle (21). Blisterpackung nach einem der Ansprüche 1 bis 3, wobei erste und zweite Folienschicht miteinander verklebt sind.Blister pack according to one of claims 1 to 3, wherein the first and second film layers are glued together. Blisterpackung nach einem der Ansprüche 1 bis 4, wobei die erste Folienschicht (24) aus einem luft- und wasserdampfundurchlässigen Material ausgebildet ist.Blister pack according to one of claims 1 to 4, wherein the first film layer (24) is formed from an air and water vapor impermeable material. Blisterpackung nach einem der Ansprüche 1 bis 5, wobei die erste Folienschicht (24) aus Aluminium- oder Kunststoffolie ausgebildet ist.Blister pack according to one of claims 1 to 5, wherein the first film layer (24) made of aluminum or plastic film is formed. Blisterpackung nach einem der Ansprüche 1 bis 6, wobei die erste Folienschicht (24) eine Dicke von 0,002 mm bis 0,05 mm aufweist.Blister pack according to one of claims 1 to 6, wherein the first film layer (24) has a thickness of 0.002 mm to 0.05 mm. Blisterpackung nach einem der Ansprüche 1 bis 7, wobei die zweite Folienschicht (26) aus einem mechanisch steifen Material ausgebildet ist.Blister pack according to one of claims 1 to 7, wherein the second film layer (26) is formed of a mechanically rigid material. Blisterpackung nach einem der Ansprüche 1 bis 8, wobei die zweite Folienschicht (26) aus Papier-, Karton- oder Kunststoffmaterial ausgebildet ist.Blister pack according to one of claims 1 to 8, wherein the second film layer (26) made of paper, cardboard or plastic material is formed. Blisterpackung nach einem der Ansprüche 1 bis 9, wobei die zweite Folienschicht (26) eine Dicke von 0,005 mm bis 0,5 mm aufweist.Blister pack according to one of claims 1 to 9, wherein the second film layer (26) has a thickness of 0.005 mm to 0.5 mm. Blisterpackung nach einem der Ansprüche 1 bis 10, wobei die Tiefe der Perforationsabschnitte (28) der Dicke der zweiten Folienschicht (26) entspricht.Blister pack according to one of claims 1 to 10, wherein the depth of the perforation sections (28) corresponds to the thickness of the second film layer (26). Blisterpackung nach einem der Ansprüche 1 bis 11, wobei die zweite Folienschicht (26) auf ihrer Außenseite eine maschinenlesbare Kennung (32) zur Produktidentifizierung aufweist.Blister pack according to one of claims 1 to 11, wherein the second film layer (26) on its outer side has a machine-readable identifier (32) for product identification. Blisterpackung nach einem der Ansprüche 1 bis 12, wobei die zweite Folienschicht (26) eine dunkle Oberfläche aufweist..A blister pack according to any one of claims 1 to 12, wherein the second film layer (26) has a dark surface. Blisterpackung nach einem der Ansprüche 1 bis 13, welche Blisterpackung (20) als Endlos-Streifenblister ausgebildet ist.Blister pack according to one of claims 1 to 13, which blister pack (20) is designed as a continuous strip blister. Verfahren zur vorübergehenden Lagerung von Produkten, insbesondere Medikamenten, in mehreren, jeweils durch eine Folie (25) verschlossenen Aufnahmefächern (21) einer Blisterpackung (20), welche Folie (25) gebildet ist durch eine erste und eine zweite Folienschicht, aufweisend die Schritte: - maschinelles Befüllen der Aufnahmefächer (21) mit jeweils wenigstens einer Produkteinheit (30), - Verschließen der Aufnahmefächer (21) mit der Folie (25), - Versehen der zweiten Folienschicht (26) mit Perforationsabschnitten (28) im Bereich der Aufnahmefächer (21), die bei Ausübung einer mechanischen Kraft über die Produkteinheit (30) auf die Folie (25) eine definierte Aufreißlinie der Folie (25) bilden, - maschinelle Entnahme der Produkte aus den Aufnahmefächern (21) durch Ausüben einer mechanischen Kraft über die Produkteinheit (30) auf die Folie (25), wobei die Folie (25) entlang der Perforationsabschnitte (28) aufreißt. Method for the temporary storage of products, in particular medicaments, in a plurality of receptacles (21) of a blister pack (20), each closed by a film (25), which film (25) is formed by a first and a second film layer, comprising the steps: - Machine filling the receiving compartments (21) each having at least one product unit (30), Closing the receiving compartments (21) with the film (25), Providing the second film layer (26) with perforation sections (28) in the region of the receiving compartments (21) which form a defined tear line of the film (25) on the film (25) when a mechanical force is exerted on the product unit (30), - Removing the products from the receiving compartments (21) by applying a mechanical force on the product unit (30) on the film (25), wherein the film (25) along the perforation sections (28) ruptures. Verfahren nach Anspruch 15, wobei der Verfahrensschritt der Bildung der Perforationsabschnitte (28) der zweiten Folienschicht (26) mittels eines Laserstrahls durchgeführt wird.The method of claim 15, wherein the step of forming the perforation sections (28) of the second film layer (26) is performed by means of a laser beam. Verfahren nach Anspruch 15 oder 16, wobei die Perforationsabschnitte (28) der Form und/oder Größe des in dem Aufnahmefach aufgenommenen Produktes (30) angepaßt werden.The method of claim 15 or 16, wherein the perforation sections (28) are adapted to the shape and / or size of the product (30) received in the receptacle. Verfahren nach einem der Ansprüche 15 bis 17, wobei die Blisterpackung (20) als Endlos-Streifenblister (20) ausgebildet ist.Method according to one of claims 15 to 17, wherein the blister pack (20) is formed as a continuous strip blister (20). Verfahren nach einem der Ansprüche 15 bis 18, wobei der Verfahrensschritt der maschinellen Entnahme der Produkteinheiten (30) aus den Aufnahmefächern (21) mittels jedem der Aufnahmefächer (21) zugeordneten, taktgesteuerten Stößeln durchgeführt wird.A method according to any one of claims 15 to 18, wherein the step of mechanically removing the product units (30) from the receiving compartments (21) is performed by means of each of the storage compartments (21) associated with clock-controlled rams. Verfahren nach einem der Ansprüche 15 bis 19, wobei der Verfahrensschritt der Bildung der Perforationsabschnitte (28) in der zweiten Folienschicht (26) vor dem Verfahrensschritt des maschinellen Befüllens der Aufnahmefächer (21) mit den Produkteinheiten (30) ausgeführt wird.The method of any one of claims 15 to 19, wherein the step of forming the perforation sections (28) in the second film layer (26) is performed prior to the step of machine filling the receptacles (21) with the product units (30). Verfahren nach einem der Ansprüche 15 bis 20, wobei nacheinander mehrere verschiedene Medikamente (30) in jeweilige Endlos-Streifenblister (20) zur vorübergehenden Lagerung abgepackt werden.The method of any one of claims 15 to 20, wherein a plurality of different medicaments (30) are successively packaged in respective endless strip blisters (20) for temporary storage.
EP07100898A 2007-01-22 2007-01-22 Blister packages and method of temporary storage of products Not-in-force EP1947027B1 (en)

Priority Applications (7)

Application Number Priority Date Filing Date Title
EP07100898A EP1947027B1 (en) 2007-01-22 2007-01-22 Blister packages and method of temporary storage of products
DE502007003215T DE502007003215D1 (en) 2007-01-22 2007-01-22 Blister pack and method for temporary storage of products
ES07100898T ES2340958T3 (en) 2007-01-22 2007-01-22 PACKAGING OF BLISTERS AND PROCEDURE FOR THE PROVISIONAL STORAGE OF PRODUCTS.
AT07100898T ATE461876T1 (en) 2007-01-22 2007-01-22 BLISTER PACK AND METHOD FOR TEMPORARY STORAGE OF PRODUCTS
JP2009546717A JP2010516572A (en) 2007-01-22 2008-01-17 Blister packaging and method for temporary storage of products
US12/523,985 US20100072104A1 (en) 2007-01-22 2008-01-17 Blister packaging and method for the temporary storage of products
PCT/EP2008/050505 WO2008090079A1 (en) 2007-01-22 2008-01-17 Blister packaging and method for the temporary storage of products

Applications Claiming Priority (1)

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EP07100898A EP1947027B1 (en) 2007-01-22 2007-01-22 Blister packages and method of temporary storage of products

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EP1947027A1 true EP1947027A1 (en) 2008-07-23
EP1947027B1 EP1947027B1 (en) 2010-03-24

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EP (1) EP1947027B1 (en)
JP (1) JP2010516572A (en)
AT (1) ATE461876T1 (en)
DE (1) DE502007003215D1 (en)
ES (1) ES2340958T3 (en)
WO (1) WO2008090079A1 (en)

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Also Published As

Publication number Publication date
EP1947027B1 (en) 2010-03-24
DE502007003215D1 (en) 2010-05-06
WO2008090079A1 (en) 2008-07-31
JP2010516572A (en) 2010-05-20
US20100072104A1 (en) 2010-03-25
ES2340958T3 (en) 2010-06-11
ATE461876T1 (en) 2010-04-15

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