EP1904135A1 - Inhalateur pour substances pulverulentes, notamment substances medicinales - Google Patents

Inhalateur pour substances pulverulentes, notamment substances medicinales

Info

Publication number
EP1904135A1
EP1904135A1 EP06792476A EP06792476A EP1904135A1 EP 1904135 A1 EP1904135 A1 EP 1904135A1 EP 06792476 A EP06792476 A EP 06792476A EP 06792476 A EP06792476 A EP 06792476A EP 1904135 A1 EP1904135 A1 EP 1904135A1
Authority
EP
European Patent Office
Prior art keywords
inhaler
chamber
substance
metering chamber
air
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP06792476A
Other languages
German (de)
English (en)
Inventor
Alfred Von Schuckmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of EP1904135A1 publication Critical patent/EP1904135A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0091—Inhalators mechanically breath-triggered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0005—Details of inhalators; Constructional features thereof with means for agitating the medicament
    • A61M15/0006—Details of inhalators; Constructional features thereof with means for agitating the medicament using rotating means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0021—Mouthpieces therefor
    • A61M15/0025—Mouthpieces therefor with caps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/07—General characteristics of the apparatus having air pumping means
    • A61M2205/071—General characteristics of the apparatus having air pumping means hand operated
    • A61M2205/073—Syringe, piston type

Definitions

  • the invention relates first of all to an inhaler for pulverulent, in particular medicinal substances, having an air duct leading to a mouthpiece, a storage chamber for the substance and a moving metering chamber for separating a certain amount of substance from the storage chamber into the region of a transfer point to the air flow a filling device which loads the dosing chamber in the manner of a shovel is moved in a sweeping manner through the substance supply onto the dosing chamber.
  • An inhaler of the type in question is known, for example, from DE 101 06 788 A1.
  • the dosing chamber is in this case formed by a perforated plate, the division of a reproducible amount of substance being achieved by relocating a scoop part to the filling means which penetrates the substance supply.
  • the latter is formed in the form of an overflowable baffle wall. The shift to the department of the particular substance quantity is derived from a rotational movement of a handle to be performed.
  • the scoop-like loading which penetrates the substance supply is derived by the filling means from a relative movement between the dosing chamber and the storage chamber.
  • the blade-like loading by the filler takes place, for example, solely by deriving a relative movement for displacing the metering device. From a filling position in the transfer position, which relative movement can also be positively controlled, so on, for example, during the commissioning of the inhaler.
  • the Relatiwerlagerung the metering chamber to the storage chamber in this case is preferably rectilinear along an inhaler longitudinal axis.
  • the paddling movement of the filler is preferably carried out angularly offset to this.
  • the relative movements of the dosing chamber, on the one hand, and of the filling means, on the other hand take place substantially in mutually perpendicular directions relative to the storage chamber.
  • the filling means is articulated in such a way that, during a relative movement between the metering chamber and the storage chamber, this causes a blade-like, even loosening loading of the metering chamber, penetrating through the substance supply by preferential radial displacement, and thus with an always reproducible amount of substance.
  • the metering chamber is preferably formed in a rod body passing through the storage chamber, wherein further enforcement preferably takes place centrally.
  • both the dosing chamber and the associated filling means are arranged within the storage chamber, according to the relative movements of the individual parts to each other at the same time a steady loosening of the stored substance in the storage chamber is achieved.
  • the rod body also forms a line section.
  • the latter leads to the inhaler mouthpiece for possible removal of the storage chamber by Saugluftbeaufschlagung in the course of inhalation.
  • the dosing chamber is herme- table separated to the line section. This ensures that before a complete and accurate filling the dosing can not be eliminated by Saugluftbeaufschlagung. This is achieved, for example, by a one-sided sealing of the line section to the environment until the ready position of the inhaler is reached.
  • the blade-like filling agent is connected to a body forming the metering chamber, for example, to the rod body forming at the same time the conduit section.
  • the filling means is fixedly connected to the body forming the dosing chamber, according to which, in a relative movement between the dosing chamber and the storage chamber, the filling means is entrained together with the dosing chamber, in particular along the central inhaler axis.
  • the movement of the filling means towards the metering chamber takes place according to an oblique position of the storage chamber wall in relation to the direction of movement of the metering chamber, which inclined storage chamber wall effects a forced control of the filling medium in the direction of the metering chamber.
  • the blade-like loading of the dosing takes place with the substance whose reproducible amount is dependent on the size of the dosing.
  • the positive control of the filling means is preferably carried out from radially outward to radially inward in the direction of the metering chamber, which is preferably formed on the rod body.
  • the metering chamber is formed outside the outer wall of the rod body as an annular groove.
  • the annular groove preferably extends in a plane transverse to the bar extension.
  • Four filling means are preferably provided, which are connected together to the body forming the metering chamber and are forcibly displaced via the inclined position of the storage chamber wall in the direction of the metering chamber sections.
  • filling means are placed equidistant from one another about the axis of the rod body and form a closed ring in the filling position, at least in the direct allocation region to the metering chamber annular groove.
  • the urged in the direction of the dosing chamber substance can not evade accordingly, creating an exact, reproducible amount of substance is divisible.
  • the filling means are further preferably made of an elastic plastic or the like, so that after canceling the positively controlled inward displacement in the direction of the metering chamber, a lifting of the loading by the inclined walls, the spring-back movement of the filling in their
  • the filling means are lockably connected to the dosing chamber body in an overflow manner.
  • the relative movement between the metering chamber and the storage chamber and the consequent loading of the filling means for pivoting the same radially inward the relative movement between the metering chamber and pantry is continued, for the displacement of the metering chamber in the transfer point to the air flow.
  • the filling medium overflows the locking connection area to the metering chamber body, for example rod body, as a result of which the spring force released thereupon the pliers arm-like filling means moves back into the initial position.
  • the invention further relates to an inhaler for powdered, in particular medicinal substances, with an air duct leading to a mouthpiece, a storage chamber for the substance and a linearly moved metering chamber for separating a certain amount of substance from the storage chamber and transferring the substance amount into a transfer position , to transfer to the airflow, continuing by relieving a
  • Compression spring a compressed air flow can be generated, for blowing out the substance from the metering chamber regardless of a suction.
  • An inhaler of the type in question is known, for example, from DE 40 27 391 A1.
  • the amount of substance to be dispensed in the metering chamber is by linear displacement of the same by means of a push button in the transition position spent, in the course of this linear displacement of the metering chamber at the same time a displacement measure for an air piston is exempted, which air piston acts on an air reservoir.
  • a displacement measure for an air piston is exempted, which air piston acts on an air reservoir.
  • the inhaler has a protective cap that covers the mouthpiece leading to the mouth when not in use. Accordingly, it is necessary to remove the protective cap in order to use the inhaler. The relative movement between the cap and the inhaler is used to tension the compression spring. Placement of the cap on the inhaler after inhalation automatically causes the tension of the compression spring for the next use.
  • the dosing chamber is immediately protected from penetrating air humidity. Clumping of the amount of substance to be introduced into the metering chamber is thereby counteracted.
  • the dosing chamber is preferably moved to an air reservoir which can be acted upon by the pressure spring.
  • the handling of the inhaler essentially requires only the operation of the closure cap, first by screwing it onto the inhaler for pretensioning the compression spring and during the startup of the inhaler by unscrewing the closure cap to displace the divided substance into the flow path or in the direction of the pressure spring acted upon air reservoir.
  • the air reservoir is formed in the course of removing the cap between an acted upon by the compression spring air piston and a Kolbenabilitywandung.
  • the air reservoir is fluidly further in connection with the air duct leading to the mouthpiece, wherein further filled with a substance amount metering chamber in the path between air reservoir and mouthpiece can be brought is.
  • the metering chamber is preferably arranged in radial overlap to the air reservoir before triggering the compression spring, wherein further the metering communicates with a line section through which the air / substance mixture in the direction of the mouthpiece can be discharged, the compressed air from the air reservoir the Discharge chamber can flow through a distance to the metering chamber arranged radially opening into the line, according to which the substance is selectively expressed by the compressed air from the metering chamber.
  • the clearing of the metering chamber is further supported by the fact that the compressed air flows from the air reservoir in tangential orientation to the metering chamber.
  • the metering chamber as an annular groove thereby a kind of circular flow is achieved.
  • the dosing chamber and the line are preferably arranged in a central rod body which is fixed relative to the inhaler housing. This is further preferably aligned centrally coaxial with the inhaler housing.
  • the triggering of the pressure acting on the air piston compression spring can be done by pressing a shutter button.
  • the compression spring or the air piston is restrained in the ready position after removal of the cap in the cocked position. By pressing the shutter button this rest is canceled.
  • a further simplification of the handling is achieved in that the triggering of the compression spring by the user takes place as a result of generating a suction vacuum.
  • the triggering is achieved in the simplest way by vigorous inhalation, according to which it is also ensured that the user provides the required flow rate during inhalation.
  • Figure 1 shows the inhaler with attached cap in perspective.
  • FIG 3 shows the longitudinal section along the line III-III in Figure 1, concerning the closed basic position of the inhaler.
  • FIG. 4 shows a sectional view corresponding to FIG. 3, but relating to an intermediate position in the course of removing the closure cap, in which intermediate position a loading of the dosing chamber takes place by means of a filling means;
  • FIG. 5 shows the enlargement of the region V in FIG. 4;
  • FIG. 6 shows the section along the line VI-VI in Fig. 5.
  • FIG. 7 shows a further sectional representation according to the illustration in FIG. 3, but after the closure cap has been removed and the standby position of the inhaler has been reached;
  • Fig. 9 is a sectional view corresponding to Fig. 7, but after triggering a pressure spring acting on an air reservoir and thus blowing out the separated substance through the mouthpiece;
  • FIG. 10 shows the enlargement of the region X in FIG. 9;
  • FIG. 11 shows the section according to the line XI-XI in Fig. 10.
  • the illustrated inhaler 1 is realized as a convenient portable pocket device. Shape defining here is a cylindrical housing 2. Overall, the inhaler 1 has a rotationally symmetrical structure.
  • the overall hollow-cylindrical housing 2 accommodates a mouthpiece 3 which can be displaced in the axial direction of the inhaler 1 in the region of a use-side open end. This is flattened to the mouth and remains in a non-use position of the inhaler 1 as shown in Fig. 3 in a lowered position in which the mouthpiece 3 projects only partially over the facing edge of the housing of the inhaler 1.
  • Part of the inhaler 1 is also a cap 4.
  • This also has a cylindrical shape, with an outer diameter corresponding to the maximum outer diameter of the inhaler housing 2.
  • the cap 4 engages over the housing 2 in the region of an adapted diameter-reduced region of the housing. It results in about the lower third of the housing 2, a step-like radial offset of the housing 5 to the outside.
  • the thus formed housing stage 5 forms a stop surface for the cap 4.
  • the closure cap 4 is screw-connected to the inhaler housing 2, for which purpose the closure cap 4 has on the inside an internal thread 7 and, associated with the housing wall 5, an external thread 8. It is a steeply rising thread.
  • the closure cap 4 serves not only the closure of the inhaler housing 2 and the protection of the mouthpiece 3 but also, moreover, also for the preparation of the inhaler 1 for the substance delivery to be effected.
  • the closure cap 4 on the inside has a coaxial with the overall axis xx aligned, annular wall-shaped carrier 9, which is the underside of the mouthpiece 3 superior cap top 10 is connected.
  • This driver 9 has in the region of the free end facing away from the ceiling 10 a radially inwardly protruding entrainment ridge 11. This engages in the non-ready position of the inhaler 1 in a foot-side annular groove 12 of the mouthpiece 3 a.
  • the mouthpiece wall merges into a radially widening collar, which at the same time forms a support surface for the closure cap-side driver 9.
  • the mouthpiece 3 forms in the usual way a central discharge opening 14.
  • radially aligned air inlets 15 are formed in the mouthpiece wall. These are opened in a position of use towards the environment.
  • a storage chamber 16 for the powdered, in particular medicinal substance 17 is tied on the foot side.
  • the storage chamber 16 is shaped as a rotationally symmetrical component and, in the region of an upper edge edge facing the mouthpiece 3, is at the foot end of the mouthpiece 3.
  • a chamber ceiling 18 oriented perpendicular to the axis of rotation x forms the upper end of the storage chamber 16 and at the same time the foot-side closure of the mouthpiece-side discharge opening 14.
  • the Vorratshuntwandung 19 goes in the chamber ceiling 18 remote from the area in an obliquely radially inwardly sloping bottom portion 20. This is a funnel-shaped overall, with an inclination angle of about 45 °.
  • This chamber bottom 20 merges into a uniformly integrally formed, centrally attached, tubular transfer section 21. This extends coaxial with the axis of rotation x with an inner diameter corresponding to about one quarter of the inner diameter of the storage chamber 16.
  • the transfer section 21 is radially encompassed by a cup-shaped, coaxially aligned guide section 22. This extends approximately over the entire axial length of the transfer section 21 and is in the foot-side region of the chamber wall 19 on the storage chamber 16 and on this movement on the mouthpiece 3 , Guide portion 22, pantry 16 and mouthpiece 3 are therefore to be regarded as a non-separable unit, which are movable along the axis x as a whole.
  • the storage chamber 16 with integrally formed transfer section 21 and guide section 22, the discharge section A has the guide section 22 below a radial projection 24 arranged through a guide section ceiling 23 oriented transversely to the axis x. These engage in correspondingly positioned, parallel to the axis x-x extending guide grooves 25 in the housing 5.
  • the chamber bottom 20 is chamber side, i. the absorbed substance 17 facing covered by a shape-adapted, likewise funnel-shaped sliding insert 26. This is held in a form-fitting manner in the region of the chamber bottom 20 and extends further in coaxial alignment with the axis x into the transfer section 21, this with an inner diameter reduced relative to the transfer section 21.
  • This cylindrical section-shaped region of the sliding insert 26 also forms a sealing section 27.
  • the wall of the transfer section 21 is provided with tangentially oriented branch channels 28. These open radially outward into an air reservoir 29th In the between the transfer section 21 and the coaxially aligned guide section 22 left annular space engages a coaxially oriented, rotationally symmetrical shaped air piston 30 a. This is viewed in the axial direction formed with a stepped piston surface, so initially with a radially outer piston ring surface which seals radially outward via a sealing lip 31 against the inner wall of the guide portion 22. Starting from this annular piston section 32, a coaxially aligned tube section 33 extends encompassing the transfer section 21 into a region projecting beyond the transfer section 21, in which area the piston surface continues radially inward.
  • the entire discharge unit A is movable in axis alignment relative to the air piston 30, according to which the volume of the air supply reservoir 29 formed between guide section 22, transfer section 21 and air piston 30 can also be changed.
  • the pot wall 33 of the air piston 30 is surrounded by a coaxially aligned, material-uniformly connected to the air piston 30 wall 34.
  • a compression spring 35 is received, which is supported at one end to a wall 34 with the Topfwandung 33 connecting ceiling portion of the air piston 30 and the other end to a bottom portion 36 of the inhaler housing 2.
  • the latching ring 40 is fixed in the inhaler housing wall 5 and has a substantially circular plan view, wherein diametrically opposite sections of the latching ring 40 are exposed in the region of housing wall, on the outside, shaped, recessed indentations 41 for radial pressurization.
  • a two-sided pressurization of the locking ring 40 for example.
  • the inhaler housing 2 is further centrally along the axis of rotation x interspersed by a rod body 42. This is the foot side tied in the region of the housing bottom 36 and interspersed starting from here initially the radially inner region of the air piston 30. A provided in the passage area further sealing lip 43 occurs against the jacket wall of the rod body 42 for further sealing of the air storage space 29.
  • the rod body 42 further passes through the transfer section 21, thereafter the storage chamber 16 and finally the mouthpiece 3 in the region of the discharge opening 14 and forms a nozzle-like discharge section 44 at the end, ie in the region of the free end assigned to the mouthpiece 3.
  • the rod body 42 is centrally penetrated by a channel-like air channel 45, which extends from the discharge section 44 in a non-use position as shown in FIG. 3 into the region of the region of the transfer section 21 shielded by the sealing section 27.
  • the air duct 45 opens Tf örmig; forms correspondingly radially Shen extending radial openings 46. There are five such radial openings 46 evenly disposed around the air duct axis.
  • a double-lip wiper seal 47 is supported, which acts against the outer wall of the rod body 42.
  • the rod body 42 carries a metering chamber D.
  • This is formed as an annular groove 48 formed in a plane perpendicular to the axis x and extending outside the bar body 42 , This is dimensioned in its radial depth so that a massive material wall remains between the annular groove 48 and the central air duct.
  • the end portions of the arms 50 facing away from the blade ends 49 carry radially inwardly pointing thickenings 51, which receive a support disk 52 enclosing the rod body 42.
  • the preferably made of an elastic plastomer or of a rubber material holder 52 has a central hole diameter, which is adapted to the outer diameter of the rod body 42nd In the basic position, ie in the non-ready position, the filling means B with the thickenings 51 rest on the underside of the chamber ceiling 18.
  • the retaining disc 52 with respect to the rod body 42 has taken a position between two axially spaced, worked out of the rod body wall radial bulges 53.
  • the axial length of the rod body 42 is further selected so that the end provided discharge portion 44 extending beyond the free edge of the mouthpiece 3 extends directly below the cap cover 10.
  • the operation of the inhaler 1 is as follows:
  • the inhaler 1 is put into operation by unscrewing the cap 4.
  • the entire discharge unit A is displaced along the axis x via the cap-side driver 9 via the same axial dimension.
  • the storage chamber 16 is scooped up at the lowest point and the dosing chamber D is filled, which allows a complete emptying of the storage chamber 16.
  • the blade ends 49 including the filled with the substance annular groove 48 against each other; Accordingly, form a closed mold for the Ringnutö réelle so that the introduced substance can not escape. The exact portioning is thereby ensured.
  • the filling of the dosing chamber D takes place at a point in which the closure cap 4 is still in screw engagement with the inhaler housing 2.
  • the discharge unit A is displaced further axially in the cap withdrawal direction, with further displacement of the mouthpiece 3 from the lowered position relative to the inhaler housing 2 into a position exposed thereto.
  • the relative displacement relative to the inhaler housing 2 and corresponding to the fixed rod body 42 brings the rod body-side discharge section 44 closer to the chamber cover 18 which delimits the discharge opening 14 of the mouthpiece 3 and thus into the effective region of the lateral mouthpiece air inlets 15.
  • the dosing chamber D which is initially closed by the blade ends 49 of the filling means B, leaves the storage chamber 16 and reaches the diameter-adapted area of the sealing section 27. This results in a loss-free transfer of the filled dosing chamber.
  • the filler-blade ends 49 which are also initially supported on the chamber bottom 20 in the course of this further axial displacement, lead to the carry-along means B being entrained together with the entire discharge unit A, while the radial bulge 53 of the rod body 42 correspondingly projects into the displacement path. which is made possible by the elastic configuration of the support disk 52.
  • the elasticity of this support plate 52 is otherwise adjusted so that only in the course of blunt loading of the blade ends 49 via the storage chamber bottom 20, a sufficient force for overcoming the radial bead 53 is constructed.
  • the forces acting on the blade ends 49 during sliding and associated radial pivoting thereof for blading the metering chamber D are not sufficient to overcome the holding forces between the retaining washer 52 and the radial bead 53.
  • the filling means B After overflowing the corresponding radial bead 53, the filling means B lose their supporting hold, as a result of which the restoring forces of the resiliently laid arms 50 come into effect.
  • the filling agents B are slidably returned to their stretched original position via the sliding insert 26, with simultaneous axial displacement of the thickenings 51 and of the supporting disk 52 carrying them (compare FIG. 6).
  • the inhaler 1 By unscrewing the cap 4, the inhaler 1 is automatically moved to the standby position. Accordingly, only the triggering of the compression spring 35 for ejecting the separated substance out of the discharge section 44 is required.
  • This triggering can be done by the user himself as a result of generating a suction vacuum.
  • Shown is an embodiment in which the release of the compression spring 35 by pressing the fixing tube 38 to an axial movement inhibiting locking ring 40 by pressurization according to the arrows P shown in FIG. 7 takes place.
  • the locking ring 40 leaves the positive connection to the fixing tube 38, according to which the bias of the compression spring 35 is abruptly reduced, with a corresponding axial displacement of the air piston 30.
  • the air in the course of the cap screwing enlarged by a multiple air reservoir 29 via the tangentially aligned Sting channels 28 of the transfer section 21 expressed, which causes a clearing of the metering chamber D under positive influence caused by the tangential orientation of the branch channels circular flow.
  • the air / substance mixture flows through a left between the rod body 42 and the inner wall of the transfer section 21 annular space 54 toward the free end of the transfer section 21 to here through the transversely oriented radial openings 46 to enter the air passage 45.
  • the annular space 54 is closed at the foot end to the transfer section end by means of a seal 55.
  • the substance expressed via the discharge section 44 into the discharge opening 14 is inhaled with simultaneous inhalation and suction air flow constructed therewith.
  • the inhaler 1 After inhalation, the inhaler 1 is moved by screwing the cap 4 back into the normal position shown in FIG. 3, this with entrainment of the entire discharge unit A, so that the mouthpiece 3 is moved back to the original lowered position.
  • the fixing tube 38 and the air piston 30 are forcedly displaced back via the foot-side radial collar 13 of the mouthpiece 3 until it reaches a position in which the locking ring 40 falls in the locking groove 39 of the fixing tube 38 in a spring-loaded manner. for locking the air piston 30 under the applied spring preload.
  • the metering chamber D is returned to the area of the storage chamber 16.
  • the filling means B assume their initial position under forced control, with their retaining disk 52 again engaging in the section between the two radial beads 53.
  • the illustrated inhaler 1 also has a counter Z on. This is provided in the foot region of the inhaler housing 2 and initially has a toothed rim 56 aligned coaxially with the axis x, with an externally mounted scale 57, which can be read by a window 58 worked out in the housing 2.
  • the ring gear 56 cooperates with a gear transmission 59, which consists of two mutually rotatably arranged gears 60 and 61, wherein a smaller gear 60 cooperates with the ring gear 56.
  • the larger gear 61 is acted upon in each inhalation, which application of the positive axial displacement of the application unit A relative to the housing 2 is derived. So protrudes from the associated radial projection 24 from a shift finger 62 down, which acts on the gear 61 after inhalation and final screwing the cap 4 and the associated return displacement of the discharge unit A.

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Pulmonology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)

Abstract

L'invention concerne un inhalateur (1) pour substances pulvérulentes, notamment pour substances médicinales (17), comprenant un canal d'air (45) menant à un embout (3), une chambre de réserve (16) pour la substance (17) et une chambre de dosage (D) mise en mouvement, pour partager une quantité de substance déterminée hors de la chambre de réserve (16) dans la zone d'un point de transfert (U) sur le flux d'air. Un moyen de remplissage (B) chargé à la manière d'une fourche, pénétrant dans la chambre de dosage (D), est déplacé par le réservoir de substance sur la chambre de dosage (D). l'invention vise à mettre au point un inhalateur du type proposé, qui soit de structure simple, de sorte à permettre une manipulation fiable et simple, en termes de répartition d'une quantité de substance reproductible. A cet effet, il est prévu que le chargement à la manière d'une fourche (B) par le moyen de remplissage (B) résulte d'un mouvement relatif entre la chambre de dosage (D) et la chambre de réserve (16).
EP06792476A 2005-07-18 2006-07-04 Inhalateur pour substances pulverulentes, notamment substances medicinales Withdrawn EP1904135A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102005033397A DE102005033397A1 (de) 2005-07-18 2005-07-18 Inhalator für pulverförmige, insbesondere medizinische Substanzen
PCT/EP2006/063851 WO2007009872A1 (fr) 2005-07-18 2006-07-04 Inhalateur pour substances pulverulentes, notamment substances medicinales

Publications (1)

Publication Number Publication Date
EP1904135A1 true EP1904135A1 (fr) 2008-04-02

Family

ID=36942588

Family Applications (1)

Application Number Title Priority Date Filing Date
EP06792476A Withdrawn EP1904135A1 (fr) 2005-07-18 2006-07-04 Inhalateur pour substances pulverulentes, notamment substances medicinales

Country Status (4)

Country Link
US (1) US20090260626A1 (fr)
EP (1) EP1904135A1 (fr)
DE (1) DE102005033397A1 (fr)
WO (1) WO2007009872A1 (fr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102006029753A1 (de) 2006-03-10 2007-09-13 Alfred Von Schuckmann Inhalator für pulverförmige Substanzen
FR2916429B1 (fr) 2007-05-22 2012-10-05 Valois Sas Capot de protection pour tete de distribution de produit fluide.
WO2009029027A1 (fr) * 2007-08-24 2009-03-05 Astrazeneca Ab Inhalateur à enclenchement respiratoire
DE102007056263A1 (de) 2007-11-22 2009-05-28 Siegfried Generics International Ag Dosiervorrichtung zur Inhalierung einer pulverförmigen Substanz
EP2785401A1 (fr) * 2011-11-30 2014-10-08 Sanofi SA Ensemble pour dispositif d'inhalation, utilisation d'un élément d'organisation et dispositif d'inhalation
CN104203319B (zh) * 2012-01-23 2017-03-08 赛诺菲股份有限公司 用于吸入装置的剂量计数机构和吸入装置
JP2015533593A (ja) * 2012-11-12 2015-11-26 サノフィ・ソシエテ・アノニム 吸入デバイスのためのアセンブリおよび封止部材の使用
US8920364B2 (en) 2013-02-28 2014-12-30 Medtronic Xomed, Inc. Biomaterial delivery device
US8845578B2 (en) 2013-02-28 2014-09-30 Medtronic Xomed, Inc. Biomaterial delivery device
DE102015119617A1 (de) * 2015-11-13 2017-05-18 Alfred Von Schuckmann Handbetätigbarer Inhalator
EP3924023A1 (fr) * 2019-02-15 2021-12-22 Iconovo AB Inhalateur
FR3128701B1 (fr) 2021-11-04 2024-01-05 Aptar France Sas Capot d'amorçage pour dispositif de distribution de produit fluide
WO2023117932A1 (fr) * 2021-12-21 2023-06-29 Chiesi Farmaceutici S.P.A. Inhalateur de poudre
CN114522308B (zh) * 2022-02-11 2023-12-29 贝里精英包装(嘉兴)有限公司 一种带手动计量的主动型喷粉装置
WO2024015888A1 (fr) * 2022-07-14 2024-01-18 Boston Scientific Scimed, Inc. Ensemble valve pour un dispositif d'administration d'agents

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE758834A (fr) * 1969-11-13 1971-05-12 Riker Laboratoires Inc Distributeur d'aerosol actionne par inhalation
US5113855A (en) * 1990-02-14 1992-05-19 Newhouse Michael T Powder inhaler
DE4027391A1 (de) 1990-08-30 1992-03-12 Boehringer Ingelheim Kg Treibgasfreies inhalationsgeraet
WO1993003782A1 (fr) * 1991-08-15 1993-03-04 Bon F Del Inhalateur
DE10106788A1 (de) 2001-02-12 2002-08-14 Schuckmann Alfred Von Inhalator für pulverförmige, insbesondere medizinische Substanzen
EP2497514B8 (fr) * 2002-09-16 2015-12-16 Sanofi SA Inhalateur de substances en poudre, en particulier de substances médicales

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See references of WO2007009872A1 *

Also Published As

Publication number Publication date
WO2007009872A1 (fr) 2007-01-25
DE102005033397A1 (de) 2007-01-25
US20090260626A1 (en) 2009-10-22

Similar Documents

Publication Publication Date Title
EP1904135A1 (fr) Inhalateur pour substances pulverulentes, notamment substances medicinales
DE69730537T2 (de) Spender für einzeldosen
EP2214760B1 (fr) Dispositif de dosage destiné à l'inhalation d'une substance pulvérulente
EP1993644B1 (fr) Inhalateur pour substances pulvérulentes
EP2010258B1 (fr) Inhalateur de poudre seche
DE2449179C3 (de) Inhalator für pulverförmige Substanzen
EP0144625B1 (fr) Dispositif à injection
DE19708406A1 (de) Gerät zur dosierten Ausgabe von Substanzen
DE2257759A1 (de) Vorrichtung zum abzapfen von fluid aus einem aerosolbehaelter
DE69209626T2 (de) Inhalator
DE4027391A1 (de) Treibgasfreies inhalationsgeraet
DE19604838A1 (de) Vorrichtung zum Ausgeben von Flüssigkeit in abgeteilten Mengen
WO1992004067A1 (fr) Inhalateur sans gaz propulseur
EP0031900A1 (fr) Dispositif de prise de sang
EP0053329B1 (fr) Récipient pour distribuer en portions un produit de consistance pâteuse
DE7706406U1 (de) Vorrichtung fuer die abgabe von fluessigkeiten
EP3374010B1 (fr) Inhalateur pouvant être actionné manuellement
DE10047722A1 (de) Von Saugluftstrom des Benutzers aktivierbare Dosiervorrichtung
DE102009039844A1 (de) Auspressgerät
DE60013799T2 (de) Pulverinhalator
CH625695A5 (fr)
WO2010118764A1 (fr) Appareil de pompage de liquide
DE10040014A1 (de) Reinigungsgerät
DE102007053590A1 (de) Handgerät zum Inhalieren von Substanzen
WO2008125402A1 (fr) Inhalateur pour substances pulvérulentes

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20080125

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR

DAX Request for extension of the european patent (deleted)
STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20100131