EP1880953A1 - Tablet blister pack - Google Patents

Abstract

The blister packing (1) has a base part (10) connected over an articulation with a cover part (30). The cover part has a trough-shaped recess. The cover part covers an opening of a cavity (15) in a closed condition. The trough-shaped recess together with the base part forms a receiving space for product information. Sealing mediums (20,26) are provided at the base part and cover part for detachable holding of the blister packing in a closed condition. An independent claim is also included for a method for manufacturing of a blister packing.

Description

The present invention relates to a blister pack according to the preamble of patent claim 1 and a method for producing blister packs according to the preamble of patent claim 9.

Blister packs for packaging tablets have become indispensable in everyday life. In blister packs, however, not only solid pharmaceutical moldings including tablets, film-coated tablets, chewing tablets, effervescent tablets, capsules, dragees, hard and soft gelatine capsules, pellets, minitablets or suppositories can be packed, but also flowable or pourable media such as powders, granules, pastes, creams and solutions or solid objects such as ampoules and contact lenses. If in the following, for the sake of simplicity, only tablets are mentioned, the disclosure should also include the other molded parts, media and articles, unless expressly stated otherwise.

Blister packs for tablets are so widely used because they not only protect each individual tablet from gases, dirt and moisture by the hygienic individual packaging, but also allow a very simple recognition of the used tablets or even a mapping of a dosage plan.

It is known to produce bottom parts of blister packs, especially blister packs of common film types, such as PVC, PVC / PVDC, PVC / PE / PVDC, PP, PP-Al, PVDC (polyvinylidene chloride), Aclar / PVDC, COC (cyclo-olefin copolymer ), (PVC-CTFE) or OPA-ALU-PVC on special blister machines. The Blisterbodenteil can also be made of other plastics without special barrier properties, if the Durability of the contents no special demands are made. In the case of thermoformable film materials, an endless shaped film is usually fed to a heating station, in which it is heated to the temperature necessary for the molding process. After deformation, the content to be filled is introduced into the cavities and these are covered with a likewise endlessly supplied cover sheet. The cover sheet is sealed in a sealing station to the flange surfaces formed by an upper surface of the bottom part over the entire surface or only partially. Subsequently, blister packs of the desired size are punched out of the endless belt in a further work station and the ready-made blisters are fed to a packing station in which they are wrapped individually or in multiples with a package insert in a secondary or outer packaging, usually a plastic or cardboard box become.

The box is necessary not least because of the leaflet with the obligatory product information. In everyday life, the consumer often carries individual blisters without the associated boxes, for example in hand, trouser or jacket pockets, since the complete boxes are perceived as too bulky and obstructive. This leads on the one hand to the fact that the cover sheets are unprotected and can be easily damaged and on the other hand that the occasional blisters often can not find their way back into their box.

In order to prevent damage and contamination of the tablets in the loose entrained blisters was in EP 0 627 906 proposed to provide a blister pack with a hinge so that it is divided into two symmetrical parts. The blister pack can be folded along the hinge so that the two topsheet sheets are aligned and protected from mechanical injury. Integrally shaped closing elements in the area of the side edges hold the packaging against the spring force of the hinge in the closed state. The packaging according to EP 0 627 906 protects the cover sheets in the closed state, However, this does not prevent many consumers from accumulating blisters over the course of time for medicines for which no leaflets are no longer available, and which therefore can no longer be assigned by the patient to an indication and must ultimately be disposed of.

This problem was for example in the DE 202005017645 U1 is detected, and it is proposed a blister with a glued directly to the cover sheet film label that is designed as a book or booklet (booklet). In order to remove a single drug, an adhesive flap of the label designed as a booklet must be opened in each case, and when pushing out the drug, a certain opening must be additionally created by a recess, a cut or a predetermined breaking point in the base sheet of the label. It will be in the DE 202005017645 U1 also proposed to stick on the outside of the booklet a braille-coated film, so that important information is accessible to blind patients. The Braille is applied by screen printing with clearcoat. For the production of such a blister pack with glued booklet, respectively already for the production of the booklet, over the conventional blister production several additional steps and workstations are needed. On the device side and procedural side, this leads to a considerable additional effort, which in turn has a negative effect on the manufacturing costs.

The increasing mobility of people means that more and more packages are needed that are easy to carry, provide maximum product protection, and provide ample space for consumer information (inside and out). From the Applicant's product range so-called plug-in "Wallets" in handy pocket size are known as optimum packaging for blister packs. In particular, lifestyle and other high-quality products, contraceptives and drugs in the introductory or saturation phase (keyword: product revival) are in Wallets clean, appealing and presented patient friendly. However, in order to keep production costs low and to avoid an undesirable mix of materials in packaging, it is desired to replace the expensive wallet packs with simpler and cheaper packagings without sacrificing their benefits.

The German Utility Model DE 9410671 discloses a packaging for transporting sample tubes, which has a receiving part formed as a trough, which is connected via a perforated central web on the long side with a cover designed as a hood. The center bar forms a bending axis around which the lid and tray are hingedly movable. The shape of the outer contours of tub and lid are coordinated so that the lid engages the tray in the closed state form fit. A recess formed integrally on the tub collar serves as a support surface for documents to be inserted, which must be transported together with the sample tubes. The samples to be transported are filled in sample tubes. The packaging according to DE 9410671 is not suitable as packaging for pharmaceutical moldings.

It is the object of the present invention to provide new blister packs which do not have the abovementioned disadvantages. Further objects are to provide an apparatus and a method for the production of such new blister packs which do not have the disadvantages of the devices and methods on the market. In particular, new advantageous blister packs of thermoformable materials and thermoforming processes for the production of new blister packs are to be presented.

These objects are achieved by the novel blister packs according to the invention and methods for the production of blister packs according to the characterizing features of claims 1 and 9.

Other variants will become apparent from the dependent claims.

Figur 1a

eine schematische Darstellung einer ersten Ausführungsform der erfindungsgemässen Blisterverpackung im geöffnetem Zustand in einer Sicht von oben auf die Innenseite der Verpackung;

Figur 1b

die Verpackung gemäss Figur 1a im geschlossenen Zustand in einer Sicht von oben auf den Deckelteil;

Figur 1c

die Verpackung gemäss Figur 1b in einer Sicht von unten auf den Bodenteil;

Figur 1d

die Verpackung gemäss Figur 1a im offenen Zustand in einer Sicht von der Seite;

Figur 1e

eine Seitenansicht der Verpackung gemäss Figur 1d im geschlossenen Zustand;

Figur 2a

eine schematische Darstellung einer zweiten Ausführungsform der erfindungsgemässen Blisterverpackung im geöffneten Zustand in einer Sicht von oben auf die Innenseite der Verpackung;

Figur 2b

die Verpackung gemäss Figur 2a im geschlossenen Zustand in einer Sicht von unten auf den Bodenteil;

Figur 2c

die geschlossene Verpackung gemäss Figur 2b in einer Sicht von oben auf den Deckelteil;

Figur 2d

eine Seitenansicht der Verpackung gemäss Figur 2a im geschlossenen Zustand;

Figur 3a

eine Ansicht von oben auf einen Abschnitt einer Endlosfolie nach dem Verformen und nach dem Befüllen der Kavitäten mit Tabletten;

Figur 3b

einen Querschnitt durch die verformte Folie gemäss Figur 3a im Bereich von zwei Kavitäten;

Figur 3c

eine Blisterverpackung nach dem Konfektionieren der verformten Folie gemäss Figur 3a im geöffnetem Zustand in einer Sicht von oben auf die Innenseite der Verpackung, wobei die Verpackung im Wesentlichen der Verpackung gemäss Figur 1 entspricht;

Figur 3d

die Verpackung gemäss Figur 3c im geschlossenen Zustand in einer Sicht von oben auf den Deckelteil;

Figur 3e

eine Seitenansicht der Verpackung gemäss Figur 3c im geschlossenen Zustand;

Figur 4a

eine seitliche Ansicht einer weiteren Ausführungsform der erfindungsgemässen Blisterverpackung im geöffnetem Zustand;

Figur 4b

die Verpackung gemäss Figur 4a im geschlossenen Zustand in seitlicher Ansicht;

Figur 5a

eine schematische Darstellung einer weiteren Ausführungsform der erfindungsgemässen Blisterverpackung im geöffneten Zustand nach dem Konfektionieren in einer Sicht von oben auf die Innenseite der Verpackung;

Figur 5b

die Verpackung gemäss Figur 5a im geschlossenen Zustand vor dem ersten Öffnen durch den Verbraucher in einer Sicht von unten auf den Bodenteil; und

Figur 5c

die Verpackung gemäss Figur 5a im offenen Zustand nach einem erstmaligen Öffnen durch den Verbraucher.

In the drawings, various embodiments of the subject blister pack are shown and explained in the following description. It shows:

FIG. 1a

a schematic representation of a first embodiment of the inventive blister pack in the open state in a view from above on the inside of the package;

FIG. 1b

the packaging according to Figure 1a in the closed state in a view from above on the lid part;

Figure 1c

the packaging according to Figure 1b in a view from below of the bottom part;

Figure 1d

the package according to Figure 1a in the open state in a view from the side;

Figure 1e

a side view of the package according to Figure 1d in the closed state;

FIG. 2a

a schematic representation of a second embodiment of the inventive blister pack in the open state in a view from above on the inside of the package;

FIG. 2b

the package according to Figure 2a in the closed state in a view from below of the bottom part;

Figure 2c

the closed packaging according to FIG. 2b in a view from above onto the lid part;

Figure 2d

a side view of the package according to Figure 2a in the closed state;

FIG. 3a

a view from above of a portion of a continuous film after deformation and after filling the cavities with tablets;

FIG. 3b

a cross section through the deformed film according to Figure 3a in the range of two cavities;

Figure 3c

a blister pack after assembly of the deformed film according to Figure 3a in the open state in a view from above on the inside of the packaging, wherein the packaging substantially corresponds to the packaging according to Figure 1;

3d figure

the packaging according to Figure 3c in the closed state in a view from above on the lid part;

FIG. 3e

a side view of the package according to Figure 3c in the closed state;

FIG. 4a

a side view of another embodiment of the inventive blister pack in the open state;

FIG. 4b

the packaging according to Figure 4a in the closed state in a lateral view;

FIG. 5a

a schematic representation of another embodiment of the inventive blister pack in the open state after assembly in a view from above on the inside of the package;

FIG. 5b

the package according to Figure 5a in the closed state before the first opening by the consumer in a view from below of the bottom part; and

FIG. 5c

the package according to Figure 5a in the open state after a first opening by the consumer.

FIG. 1 a shows an opened blister pack 1 for pharmaceutical moldings or tablets in the opened state in a view from above. A bottom part 10 is provided with a plurality of cavities 15 for receiving the moldings. In the illustrated embodiment, fourteen circular cavities 15 in two rows uniformly spaced apart in approximately rectangular bottom portion 10 are arranged so that each cavity 15 is surrounded at the top of the bottom part 11 of a flange 16.

The flange surfaces 16 are preferably in a common plane and are used in a known manner for attachment of a cover sheet, not shown in the figure, which closes the cavity in a sealing manner. The bottom part 10 is connected at a trailing edge 12 via two joints 51, 52 with a trailing edge 32 of a cover part 30 whose basic shape is approximately congruent with that of the rectangular bottom part 10. At the respective leading edges of the bottom part 10 and cover part 30, matching closure means in the form of a recess 20 and a tab 25 are arranged, whose side regions 21, 22 and 26, 27 are elastically tongue-shaped and so on are arranged so that they can be brought into positive engagement with each other and lock by mutual engagement behind the package 1 in the closed position.

In the cover part 30, a trough-shaped recess 35 is mounted, which is discontinued in the illustrated embodiment by a peripheral shoulder 36 of front 31, rear 32 and side edges 33, 34 of the cover part 30. Since the cover part 30 of the exemplary embodiment illustrated in FIG. 1 is approximately congruent to the bottom part 10, with the packaging closed, the shoulder 36 lies with its upper side on top of the bottom part and the edges of both parts 10, 30 essentially coincide. The closing means 20, 25 arranged at the leading edges 11, 31 are shaped such that their respective leading edges in the closed state, as shown in FIGS. 1b and 1c, define a common edge without appreciable interruptions. The side edges of the closure means formed on the bottom are in extension of the side edges of the bottom part, so that no disturbing interruptions in the outer edge arise here. Together with the rounded corners, this makes the packaging not only shapely, but also pleasant to handle. The trough-shaped recess 35 stabilizes the lid member 30 and makes it torsion and bending resistant.

From the figures 1b, 1c and 1d, which show the inventive packaging according to a first embodiment in the closed and locked state, it is clear that bottom 10 and lid 30 when closing the package 1 about an axis defined by the hinges 20, 20 ' A, are pivoted until they come to lie approximately congruent to each other. The upper side 17 of the bottom part 10, which is essentially formed by the flange surfaces 16 and the receiving openings of the cavities 15, is no longer accessible from the outside when the packaging is closed. As a result, the sealed cover sheet, which is not shown in the figures, in the region of Cavities are protected against mechanical injuries, and it is ensured that the contents of the cavities remain hygienically perfect.

For the present invention, it is essential that all cavity openings in the top of the bottom part are covered and protected by the cover part.

Another essential aspect is that in the lid part 30, a trough-shaped recess 31 is attached. The recess 31 has in the illustrated embodiment, a substantially rectangular basic shape and is surrounded on all sides by a narrow circumferential shoulder 36. The recess is used to hold product information, both in the form of conventional visually detectable information carriers, so for example the known leaflets, imprints, stickers, holograms, but also in the form of electronically readable information carriers such as chips or labels for radio detection, as well RFID tags (Radio Frequency Identification Tags), or combinations of both. Especially the passive RFID tags, which usually include an antenna, a transponder, a digital circuit with memory, are particularly suitable as originality features for increasing traceability and copy security. They can be extremely advantageous fasten in the trough-shaped depressions, for example by sealing or gluing, so that they can not be removed without destruction. Since the trough-shaped depressions provide sufficient space for accommodating the RFID tags, especially for the antenna, it is possible to resort to relatively large and thus inexpensive radio tags. The RFID tags also make it possible to detect the packaging without contact and to retrieve information from the packaging or store it in the packaging. The RFID identification also proves to be extremely advantageous for electronic article surveillance and / or as an element of quality assurance. It allows, in the spirit of good distribution practices, packaging, storage and distribution Easiest way to record and make transparent for each packaging unit.

Should this be desired, it is also easy to attach a voltage source, for example a battery in the trough-shaped depression. Alone or in addition to the electronic information carriers conventional leaflets can be either loosely inserted into the recess or particularly preferably with a back directly or an adhesive edge in the recess captive fixed or repeatedly releasably glued. The leaflets 60 are folded several times depending on their size and can be very comfortably unfolded with opened package 1, as indicated in FIG. 1e, and stowed again in the recess 35 after reading the product information. Since the trough-shaped depressions provide sufficient space according to the present invention, it is also easy to accommodate whole booklets in them, which in turn can be glued into the recess with a rear cover page. The depth of the trough-shaped recesses 35 is adapted to the thickness of the male booklets or leaflets 60, and vice versa, so that they can sink completely in the recesses 35 and do not protrude beyond the defined by the surrounding shoulder 36 inner surface 37 of the lid portion 30. This ensures that the package 1, as shown in the side view of Figure 1d, can easily close and the inner surface of the rotating shoulder in the closed state on the top 17 of the bottom part 10 comes to rest, so that the receiving space from the outside not is accessible.

As can be seen from FIGS. 1d and 1e and will be explained in more detail in the following description of the production method according to the invention, the design of the hinge means is also of great importance for achieving this advantageous effect.

In the embodiment of Figure 1, the trough-shaped depression is formed so large that it covers all cavities 15 in the bottom part 10 in the closed state of the package.

Another aspect of the present invention bears legal regulations which require that the name of a drug on the outer sheaths also be indicated in braille. A flat bottom 38 of the trough-shaped recess 35, which forms the substantially flat lid top in the closed state of the packaging, is in accordance with a preferred embodiment tactile detectable information such as Braille and / or three-dimensional structures for the transmission of tactile information, especially for the blind Mistake. The most commonly used method for the production of braille, tactile information that is readable for the visually impaired and the blind, is the embossing or punching of thin materials. Rounded pins push the embossable material into an abutment, creating the necessary height and geometry for readability. When producing the packages according to the invention, when using correspondingly shaped blister forms, the braille can be formed during the deformation of the films, without the need for a further processing step or an additional adhesive label. Depending on the packaging design, Braille can also be attached to other suitable surfaces of the packaging.

For the visually impaired or, for example, age-blind persons who can not read Braille, it is also possible to affix simple tactile detectable symbols 40 or pictograms, as shown in FIG. 2c. Of course, you can also attach company logos or trademarks in this way.

The blister packs according to the invention preferably comprise a base element which is produced in one piece from at least one bottom part, a cover part and a joint, wherein the closure means are each integrally formed on the bottom and top part.

These basic elements are preferably formed from the sheet materials already mentioned above by deep drawing and subsequent punching.

In particularly preferred embodiments, the basic elements are deep-drawn only from one side, so that they can be formed extremely efficiently with a single mold set on the known blister machines. The exemplary embodiments of FIGS. 1 and 2 show blister packs with such basic elements in which, in a planar film, in a first and only deformation step, all the cavities, depressions, Braille and grooves for the hinges are formed in only one direction.

The main bodies of the blister packs according to the invention are preferably made of conventional thermoformable film types, such as PVC, PVC / PVDC, PVC / PE / PVDC, PP, PP-Al, PVDC (polyvinylidene chloride), Aclar / PVDC, COC (cyclo-olefin copolymer), (PVC-CTFE) or OPA-ALU-PVC on known blister machines. As already mentioned, the production of the base body is preferably carried out by deep-drawing, but they can also be produced by casting, vacuum forming or embossing. In the latter case, primarily metal foils, for example made of aluminum, or metal-plastic composite foils are used. All of the aforementioned materials have in common that they have very good impermeability to gases and water vapor. If no special requirements are placed on the shelf life of the packaged products, then other plastics without special barrier properties can also be used for producing the basic body, that is to say the floor parts and the lid parts. In the case of thermoformable film materials, an endless shaped film is usually fed to a heating station, in which it is heated to the temperature necessary for the molding process.

As already mentioned, according to a preferred embodiment of the method according to the invention, the thermal film is only from one side, preferably after below, deep-drawn. An important advantage of this method is that the tooling costs are low and the workstation can be kept very simple. The cycle times in the simple deformation step are very short, so that an extremely efficient production is possible. FIG. 3 shows a section of a continuous film after deep drawing in a plan view and in section. After deformation, the content to be filled is metered in a subsequent workstation in the cavities in the bottom part and these are covered in another workstation with a likewise endless supplied cover sheet and sealed or glued. As cover sheets for blister packs, hard films such as aluminum foil, for example 0.020 mm thick, or composite foils comprising aluminum foil or thermo-foils having a weight of, for example, 5 to 6 g / m ² or paper / PE composite films are preferably used. As cover sheets for peel packaging preferably thicker films or composite films are used.

The trough-shaped depressions in the lid part are also filled after deformation. Since they are usually not sealed, the filling can be done before or after the filling or sealing of the cavities in the bottom part, or even after the packaging. Depending on the wishes and purpose of use, leaflets, leaflets, booklets and / or electronic product information (for example RFID tags) are inserted into the depression and possibly welded or glued in place. If transparent film material is used to produce the basic body, it is also possible to glue a label which is visible from the outside for the visually detectable marking of the packaging when the packaging is closed.

After the sealing station is made up, that is, the present as an endless belt body whose cavities are filled and sealed, cut or punched to the desired size and the desired outline. In the figure 3c is an example shown for a package after passing through the punching station, in which in the punching process, the closure means 20, 25 and the joints 20, 20 'were formed.

After assembly, unless the trough-shaped depression still has to be filled, the packaging is folded together along the joints and the closure means are closed. As a first-opening guarantee and / or for child safety ground and cover part can still be secured with suitable adhesive labels or seals, which are preferably in the region of the closure means this completely or partially overlapping, or secured by releasable partial bonding or welding of the bottom and lid part.

If desired, the finished blister packs can also be individually or in several wrap in a secondary packaging, for example, a plastic or cardboard box. Usually, however, can be dispensed with in the manufacture of the cartoner and the finished sealed blister packs are fed directly to a packaging station, where they can be filled into transport packaging for delivery to wholesalers and intermediaries.

The manufacturing method for the blister packs according to the invention will be explained in more detail below with reference to the embodiment of FIG. The production methods according to the invention can be carried out on blister machines which can be produced by modification of known thermoforming machines or blister machines without great expense. On the presentation of the new blister machines in the figures has been omitted. Of the known blister machines, they differ essentially in that one or more stations for filling the trough-shaped depression and a device for closing the packaging are provided. These can easily be retrofitted to existing systems, or even integrated into existing workstations. According to customer requirements can be dispensed with a packaging station for wrapping multiple blister packs in separate outer packaging and on the supply of a leaflet in this outer packaging.

According to a preferred embodiment of the production method according to the invention, thermoformable endless films 2 are deep-drawn in a format set, wherein the packaging base body is shaped such that only one deep-drawing tool / blister mold is necessary for its production. The cup of the thermoforming tool is shaped in the present example such that in one step a plurality of cavities 15, a central groove 3 and a trough-shaped depression 35 with braille 39 are formed in the film 2, as can be seen in FIG.

FIG. 3b shows a section through the shaped film 2 in the region of the cavities 15, wherein the cavities and the trough-shaped depression are not yet shown filled. In the figure 3a, the tablets F are already filled into the cavities 15, but these are not yet sealed with the cover sheet. The area to the right of the groove 3 is not sealed because the trough-shaped depression still needs to be filled. The film 2 defines a ground plane G from which all deformations of the body, in the present example, the cavities 15, the groove 3 and the trough-shaped recess 35 are directed with Braille 39 down. The geometry of the deformations, which are mounted in the thermoformable endless films, according to preferred embodiments, designed so that the deformation can be performed only with air and on a mechanical pre-deformation, for example with Teflon punches, can be omitted. The bottom 4 of the film 2 forms in the finished and closed packaging the outside, that is, the bottom of the bottom part and the top of the lid part. Since the starting material for the packaging base body, comprising the bottom part, cover part and joint means and closure means, is a flat film, it is advisable that the proportions of the base body, the closed with the package to each other come to define a common level in manufacturing. Since the hinge means are formed from the deformation of groove 3 during the subsequent punching, it is generally important that their dimensioning, especially their width and depth, allows complete closure of the package. A pivotal movement of the cover part by approximately 180 ° must be possible so that it can be brought into contact with the shoulders 36 at the peripheral edge regions of the surface of the bottom part at least. The strength of the film, together with its material properties, has a decisive influence on the force required to close the package. About the geometry of the groove 3 (width, depth and shape), but above all on the length and number of hinge means, the stopping force can be adjusted so that the package can be held against the spring action of the hinge means of the closure means in a closed position and does not open by itself.

Punching is preferably again with a single punching tool. On the sides of the endless film each lost edges of 5 to 7 mm are provided, where the film can be held during punching.

FIG. 3c shows the prefabricated packaging base body after punching in a view of the interior of the opened packaging, wherein the cover sheet foil is not shown in the drawing over the cavities 15 filled with tablets F and the trough-shaped depression 35 has not yet been filled. When punching most of the film was removed in the region of the groove 3, so that only two hinges 51, 52 remain, which engage at respective trailing edges 12, 32 of the bottom part 10 and cover part 30 and connect these pivotally with each other. In the thermoforming tool, instead of one continuous groove, one or more short grooves may be provided which are limited to the region of the hinges.

During assembly, the closure means 20, 25 have been punched out at the leading edges 11 and 31 of the bottom part 10 and lid part 30. Analogous to the embodiment of Figure 1, the side portions 21, 22 and 26, 27 of the closure means 20, 25 are elastically tongue-shaped and arranged such that they can be brought into positive engagement with each other and lock by mutual engagement behind the package 1 in the closed position, such as it is shown in the figure 3d in a view from above on the lid part. In the present embodiment, the closing of the packaging is done by machine after the leaflet 60 has been inserted into the trough-shaped depression. In the side view according to Figure 3e, the transparent packaging is shown in the closed state. The leaflet 60 is folded several times in the recess 35, at the bottom 38, the individual Braille points 39 protrude upwards. The upper side 17 of the base part, at which the cavity openings open, is completely covered by the cover part and thus protected. The trough-shaped recess 35 is so large that it covers all Kavitätenöffnungen in the present embodiment in the closed state and only a narrow circumferential shoulder 36 comes to rest on the top cover. Preferably, the trough-shaped depressions according to the present invention are so large that at least several of the cavity openings are covered in the bottom part.

In further preferred embodiments, only one or two cavities, for example for so-called "one-dose" products, are arranged in the bottom part. Here, it has the advantage that the new blister pack offers sufficient space for accommodating the product information despite minimal material expenditure.

A field 6, which is drawn in the packaging according to FIGS. 3c and 3d, is intended to indicate that it can be applied on a suitable surface of the base body in a known manner, for example a date embossing, by means of a marking or embossing tool.

Since virtually no material flow is generated during deep drawing, for example, a selective partial weakening of the film in the region of a desired hinge axis by means of a perforation tool is necessary for creating alternative film hinge-like joint means.

According to further preferred embodiments of the invention, two or more blister molds are operated simultaneously on a system in order to increase the capacity accordingly.

The novel advantages of the new blister packaging are also present in the packaging according to a further embodiment, as shown in FIG. The packaging 1 'can in turn be delivered without folding box, since the cover part 30' protects the inner top surface of the bottom part 10 'mechanically against the action of, for example, pointed objects. A first opening guarantee and a child safety lock are possible. A label can be glued into the trough-shaped depression and / or insert or glue in the leaflet and or attach an electronic label. On the trough-shaped depression Braille can be attached by deformation. After opening the pack, tablets, leaflet, electronic label and Braille always stay together. The closing means are formed in the embodiment according to FIG. 2 by a tongue 28 formed on the cover part and a slot 29 mounted in the bottom part 10 '. From Figures 2b and 2c shows how the tongue 28 holds by inserting into the slot 29, the package 1 'in the closed position. Slit 29 and tongue 28 can in turn be made during assembly by punching or cutting. Instead of the fourteen circular cavities, as shown in the packaging according to FIGS. 1 and 3, seven elongated cavities 18 are provided in the bottom part 10 'of the package 1' for receiving correspondingly shaped dragees or capsules.

In a further, illustrated in Figure 5, embodiment according to the present invention, the closure means are substantially as shown in Figure 1 formed, but additionally include a Erstöffnungsschutz in the form of a securing tab 8, between the two tongue-shaped side portions 21, 22 at the bottom part 10 is arranged. 5a shows the blister pack 1 "after being assembled in the open position, with the cover sheet and tablets not being drawn again A predetermined breaking point 9 is provided between the securing tab 8 and the front edge 11 of the bottom part punched perforation or scribing or one or more partial cuts made by a blade placed in the blister machine as it passes through the securing tab in the film When the package 1 "is closed, the securing tab 8 engages the tab 25 lie as shown in Figure 5b. The two tabs are connected to each other, for example by gluing or welding, so that they can no longer be detached from each other without destroying each other. This ensures that when the package 1 is opened, the weakened film material breaks in the area of the predetermined breaking point 9 and the securing tab 8 remains liable to adhere to the tab 25, as shown in FIG. 5c.

Without departing from the inventive idea, a blister pack can be produced with a basic body which, in addition to the lid and bottom part, also comprises additional additional bottom and / or lid parts. In FIG. 4, for example, a second cover part 70 is formed via second hinge means 71 on a front edge of a first cover part, which has a second trough-shaped depression 72. Second cover part and second recess are dimensioned so that when the packaging is closed, the bottom part 73, in particular the cavities mounted therein, are completely accommodated in the second trough-shaped depression 72. The second cover part 70 additionally protects the bottom part from the bottom against mechanical influences and, with sufficient depth of the second trough-shaped depression 72, forms another reservoir when the packaging is closed For example, product information is shown in FIG. 4. It can be seen that the extended basic body can also be produced by deep drawing in only one direction. As a closure means a staple strip 74 is pivotally mounted on a front edge of the second cover part 70. To close the folded package, the staple bar is clamped over the edge formed by the bottom part and the first lid part with a bead formed by the first hinge means 75.

Instead of a first bottom part and a first lid part, the packaging according to the invention can also comprise two bottom parts which can be folded on top of each other by means of hinge means, so that in turn a lid part with a trough-shaped depression of sufficient size receives a first bottom part. Also, this package can be produced in a single deep drawing step, which in turn must be deformed only in one direction.

Previously, only embodiments of the inventive packaging were described in which the base body is formed by deep drawing of thermoformable films from only one side. With corresponding format sets, however, bilateral deformations (positive and negative) are also possible. In particular, in the embodiment of the closure means allows a two-sided deformation many other embodiments. Examples of this can be the EP 0 627 906 are removed, the content of which is hereby incorporated into this application.

According to further embodiments not shown in the figures, the at least one cavity is designed to receive an inner blister, which in turn is provided with at least one cavity for receiving products. The cavities of the inner blister are either unsealed or they have a cover sheet that covers the openings of the cavities. This second cover sheet is, in turn, sealed to a flange surface surrounding the cavities. After inserting the filled inner blister in a cavity in the bottom part of the blister pack according to the invention, it is sealed with a first cover sheet film. The dimensions of the inner blisters are preferably adapted to the size of the receiving cavity in the bottom part of the packaging, so that the inserted inner blister is securely held in the cavity and the first cover sheet is not damaged by the inner blister even when moving the packaging. In a sterile embodiment of the inner blister pack, the products in the inner blister are packaged sterile in the at least one cavity in the inner blister and sealed under sterile conditions. This "sterile" sealed inner blister can now be placed under unsterile conditions in the receiving cavity in the bottom part. Subsequently, the cavity is sealed in the bottom part with the first cover sheet. If sterility requirements are not met, the inner blister can be placed in the receiving cavity in an unsterile (with or without a second cover sheet) and then sealed with the first cover sheet.

Due to the cheap and simple production, the new blister packs are not only suitable for the production of large lots, but also for research and development, clinical trials, stability studies and production of small lots. Especially with the packaging for clinical trials come as a further advantage to bear that the trough-shaped depressions on the one hand offer plenty of room for extensive often multilingual leaflets, brochures or booklets and on the other hand can be ensured that even after opening the pack, the packaged pharmaceutical product and the Product information in printed and electronic form remain together.

List of reference numbers

1, 1 ', 1 "

blister

2

Thermoforming film

3

groove

4

Film base

5

Foil top

6

date stamp

8th

securing tab

9

Breaking point

10

the bottom part

11

leading edge

12

trailing edge

13

side edge

14

side edge

15

cavity

16

flange

17

Top floor part

19

cavity

20

recess

21

Tongue-shaped side area

22

Tongue-shaped side area

25

flap

26

Tongue-shaped side area

27

Tongue-shaped side area

28

tongue

29

slot

30

cover part

31

leading edge

32

trailing edge

33

side edge

34

side edge

35, 35 '

trough-shaped depression

36

shoulder

37

inner surface

39

braille

40

symbols

51

hinge

52

hinge

60

leaflet

70

second cover part

71

second hinge means

72

second trough-shaped depression

73

the bottom part

74

clamp bar

75

first hinge means

76

cavity

A

hinge axis

G

ground plane

F

moldings

Claims (14)

Blister pack (1, 1 ', 1 ") for having a bottom part (10, 10', 10") with at least one cavity (15, 18, 76) for receiving pharmaceutical moldings (F) and one, the at least one cavity (15 , 18, 76) surrounding flange surface (16) for fixing a, an opening of the at least one cavity (15, 18, 76) covering, cover sheet, characterized in that the bottom part (10, 10 ', 73) via at least one joint (51, 52, 75) is connected to a cover part (30, 30 ') which has a trough-shaped recess (35), wherein the cover part (30, 30') in a closed state at least the opening of the at least one cavity (15 , 18, 76) and the trough-shaped recess (35) in cooperation with the bottom part (10, 10 ', 73) forms a receiving space for product information and that closure means (20, 26, 74) on the bottom part (10, 10', 73 ) and cover part (30, 30 ') are provided for releasably holding the blister pack (1, 1', 10 ") in one closed state. Blister pack (1, 1 ', 1 ") according to claim 1, characterized in that the trough-shaped recess (35) is surrounded on all sides by a peripheral shoulder (36) which in the closed state of the packaging on the upper side (17) of the bottom part ( 10, 10 ', 10 ") comes to rest, so that the receiving space from the outside is not accessible. Blister pack (1, 1 ', 1 ") according to claim 1 or 2, characterized in that the base surfaces of bottom part (10, 10', 10", 73) and cover part (30, 30 ') are formed approximately congruent. Blister pack (1, 1 ', 1 ") according to one of the preceding claims 1 to 3, characterized in that the trough-shaped recess (35) in the closed state of the package all cavities (15, 18, 76) in the bottom part (10, 10' , 10 ", 73). Blister pack (1, 1 ', 1 ") according to one of the preceding claims 1 to 4, characterized in that a bottom (38) of the trough-shaped recess (35) forms a lid top substantially flat in the closed state of the package. Blister pack (1, 1 ', 1 ") according to claim 5, characterized in that on the top cover tactile detectable information such as Braille (39) and / or three-dimensional symbols (40), pictograms and / or logos are attached. Blister pack (1, 1 ', 1 ") according to one of the preceding claims, characterized in that the bottom part (10, 10', 10", 73), cover part (30, 30 ') and joint (51, 52) is a one-piece main body form, which is formed from a sheet material, preferably by deep drawing and stamping. Blister pack (1, 1 ', 1 ") according to any one of the preceding claims, characterized in that the bottom part (10, 10', 10", 73) and cover part (30, 30 ') are interconnected by a Erstöffnungsschutz, wherein the Erstöffnungsschutz (9, 8) as part of the closure means (20, 26, 74) or separately formed. Blister pack (1, 1 ', 1 ") according to one of the preceding claims, characterized in that an inner blister in the at least one cavity (15, 18, 76) the bottom part (10, 10 ', 10 ", 73) is removably arranged, wherein the inner blister comprises at least one cavity. A method for producing a blister pack for pharmaceutical moldings, characterized in that by deformation and subsequent assembly of a deformable film, a base body, comprising at least one bottom part, at least one lid part, hinge means and closure means is formed, wherein formed in the at least one lid part during deformation a trough-shaped depression which is filled with product information before or after assembly. A method according to claim 10, characterized in that the film is a thermoformable film and the deformation takes place by deep drawing in only one direction. A method according to claim 10 or 11, characterized in that the product information comprises an electronic label, preferably an RFID chip, are stored on the information about the packaged pharmaceutical moldings. Method according to one of claims 10 to 12, characterized in that during deformation tactile detectable information, preferably in Braille or Braille, are formed during deformation on a surface accessible from the outside when the packaging is closed. Method according to one of claims 10 to 13, characterized in that in the finished molded, ready-made and filled packaging bottom part and lid part are mechanically folded around an axis formed by the hinge means and the closure means are locked.

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