EP1799583B1 - Nichtwiederverschliessbare verpackung für gesundheits-gefährdende erzeugnisse - Google Patents

Nichtwiederverschliessbare verpackung für gesundheits-gefährdende erzeugnisse Download PDF

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Publication number
EP1799583B1
EP1799583B1 EP05792509A EP05792509A EP1799583B1 EP 1799583 B1 EP1799583 B1 EP 1799583B1 EP 05792509 A EP05792509 A EP 05792509A EP 05792509 A EP05792509 A EP 05792509A EP 1799583 B1 EP1799583 B1 EP 1799583B1
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EP
European Patent Office
Prior art keywords
packaging material
material elements
packaging
package
surface section
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
EP05792509A
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German (de)
English (en)
French (fr)
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EP1799583A1 (de
Inventor
Karin Ludwig
Michael Horstmann
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LTS Lohmann Therapie Systeme AG
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LTS Lohmann Therapie Systeme AG
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Priority to PL05792509T priority Critical patent/PL1799583T3/pl
Publication of EP1799583A1 publication Critical patent/EP1799583A1/de
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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D75/00—Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes, or webs of flexible sheet material, e.g. in folded wrappers
    • B65D75/52—Details
    • B65D75/58—Opening or contents-removing devices added or incorporated during package manufacture
    • B65D75/5855—Peelable seals
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D75/00—Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes, or webs of flexible sheet material, e.g. in folded wrappers
    • B65D75/28—Articles or materials wholly enclosed in composite wrappers, i.e. wrappers formed by associating or interconnecting two or more sheets or blanks
    • B65D75/30—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D75/00—Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes, or webs of flexible sheet material, e.g. in folded wrappers
    • B65D75/52—Details
    • B65D75/58—Opening or contents-removing devices added or incorporated during package manufacture
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D75/00—Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes, or webs of flexible sheet material, e.g. in folded wrappers
    • B65D75/52—Details
    • B65D75/58—Opening or contents-removing devices added or incorporated during package manufacture
    • B65D75/5805—Opening or contents-removing devices added or incorporated during package manufacture for tearing a side strip parallel and next to the edge, e.g. by means of a line of weakness
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D2215/00—Child-proof means
    • B65D2215/04—Child-proof means requiring the combination of different actions in succession

Definitions

  • the invention relates to non-resealable packaging for hazardous products, in particular for pharmaceutical products. It further relates to methods for producing such packages and for packaging products by means of these packages.
  • Packaging intended for the packaging of potentially hazardous products is subject to increased safety requirements in order to prevent unauthorized removal or misuse of these products.
  • in the packaging of medicines must be ensured by appropriate measures that the packaged product can not be removed by children from the package.
  • child-resistant packaging of various types has been developed and for the testing of child safety internationally standardized testing procedures have been introduced (DIN EN 862 concerning non-reclosable packaging for non-pharmaceutical products; DIN EN 14375 concerning non-reclosable packaging for pharmaceutical products.
  • a child-resistant medication packaging must be such that, for example, older people are able to open them independently and within a few minutes DE 20 2004 003781 U1 for example, discloses such a package.
  • the packages of the present invention are non-resealable packages having at least one releasable connection (eg, sealed seam).
  • the opening is carried out in such a way that one or more detachable connections are released manually by pulling apart, without the aid of tools or tools, whereby the packaged product is accessible and can be removed through the resulting opening.
  • Object of the present invention was to provide a package of the aforementioned type, which is suitable for the packaging of potentially harmful products and which is particularly suitable as a child-resistant packaging, and which allows the intended handling in a simple manner.
  • the package has at least a first surface portion, at the edge or edges of the two packaging material elements are releasably connected to each other, wherein between the two packaging material elements at least one side enclosed cavity for receiving the packaged goods is formed.
  • the package has at least one second surface portion lying outside of or adjacent to said first surface portion and at its edge or edges the two packaging material elements are detachably connected to each other.
  • At least one of the two packaging material elements is provided with at least one structure which extends within the second surface portion (12) and which permits tearing of the packaging material element (s).
  • the opening of the package is generally carried out in the manner that one of the two packaging material elements, or both, is torn within the second surface portion by means of finger power, wherein said structure is started.
  • two freely accessible edges of the packaging material elements are created, which can serve as grasping aids or grasping lugs, in order to separate the detachable connections between the two packaging material elements.
  • the releasable connections in the first surface section are thereby also released, as a result of which the cavity becomes accessible to the packaged goods.
  • packaging materials used for the production of packaging material elements must have a tensile strength that is sufficiently high, so that the package in the undamaged state without the aid of aids such. B. tools can be destroyed.
  • Suitable packaging materials for this purpose are known to the person skilled in the art; For example, foil-shaped, flexible materials made of plastic, metal (eg aluminum) or composites of the substances mentioned can be used. As film-shaped materials both monofilms and two- or multi-layer laminates can be used.
  • Suitable plastic materials are, in particular, the following, individually or in combinations: polyesters (eg polyethylene terephthalate), polyethylene (eg HDPE, LDPE), polypropylene, polyisobutylene, polystyrene, polyvinyl chloride, polyamides, polycarbonate, cellulose acetate.
  • the thickness of the film-shaped materials is preferably in the range of 5 to 300 .mu.m, more preferably 50 to 200 .mu.m.
  • Barex® BP Chemicals
  • Barex is a copolymer of acrylonitrile and butadiene.
  • Barex is available by graft polymerization from 73-77 parts of acrylonitrile and 23-27 parts of methyl acrylate in the presence of 8-18 parts of a butadiene-acrylonitrile copolymer having a content of about 70% butadiene.
  • Barex is the sealable part of a packaging composite. It is a material with exceptionally high chemical inertia and provides an excellent oxygen barrier, but has some permeability to water vapor. Due to its good barrier properties and chemical resistance, it is particularly suitable for packaging medicines containing aggressive and / or volatile substances, eg. B. nicotine.
  • the two packaging material elements can be made of the same materials, or of different materials.
  • at least one of the two packaging material elements consists of transparent material (eg transparent plastic film).
  • the invention includes embodiments in which a packaging material element or both packaging material elements are dyed the same or different, which may each be a transparent or opaque coloring.
  • one of the two packaging material elements may be made of a non-transparent composite of paper (or paperboard) with plastics (eg, polyethylene or polyethylene terephthalate coated papers), and the second packaging material element may be made of a transparent, colorless, or colored plastic film.
  • plastics eg, polyethylene or polyethylene terephthalate coated papers
  • the second packaging material element may be made of a transparent, colorless, or colored plastic film.
  • at least one surface of the carrier layer or / and the cover layer is metallised (eg coated with aluminum).
  • the said releasable connections are preferably formed by sealing seams or sealing surfaces.
  • peelable film coatings peel lacquer
  • hot melt adhesive can be used as the sealing medium.
  • suitable sealants and sealing methods are known in the art, for. B. sealants based on polyethylene-LD or ethylene vinyl acetate copolymers). Both heat sealing and cold sealing methods are contemplated.
  • the peel-capable compound is produced by heat sealing at temperatures in the range between 50 ° C and 250 ° C, especially 50 to 200 ° C, using hotmelts.
  • the sealing seams or sealing surfaces preferably have a width of 0.1 mm to 10 cm, in particular 1 mm to 2 cm, and they preferably extend over the entire length or width of the packaging material elements. To open the In addition to complicate packaging, at least one of the sealing seams may be formed wider than the other sealing seams.
  • the said structure which allows tearing of the packaging material element (s), can be present in one of the two packaging material elements or in both, with the last-mentioned embodiment being preferred.
  • these structures (s) in both packaging material elements are preferably configured the same or similar and arranged congruent to one another.
  • structures which allow the tearing of the / the packaging material elements are preferably: straight cuts; serrated or wavy cuts; Perforations, in particular perforations of successively arranged points and / or cuts; Material recesses; Punches, in particular arrow-shaped, triangular or diamond-shaped punches; Predetermined breaking points.
  • said structure (s) are arranged peripherally within said second area portion, i. H. in the vicinity of the edge connecting the two packaging material elements (eg sealed seam or sealing surface), but not within this edge.
  • said invention also includes other embodiments in which said structure extends partially into the sealed edge area.
  • the tearing structure in no case extends to the outer edge of the package.
  • the package is advantageous to have the package to be provided with a fold line or crease line, for example by embossing or pinching. Suitable methods for this purpose are known to the person skilled in the art.
  • Said structure, or at least one of these structures is preferably arranged so that it intersects the fold line or crease line, for example at right angles or at an oblique angle, starting from the inner area of the second area section, so that this structure is located on both sides of the fold line. or crease line runs. But at least the tearing structure should approach and touch the fold or crease line.
  • the tear structure By designing the tear structure to cut the fold or crease line as described, the tearing process is greatly facilitated without compromising child safety of the package. This is particularly important in view of the intended use of the packaging by older persons, since in this case too it must be ensured that the packaging can be opened without the aid of tools or other aids, and that the opening can be opened within a short period of time without frustrating attempts is possible.
  • the first packaging material element is formed from a single- or multi-layer film, and that this packaging material element is provided with one or more of said structures.
  • the second packaging material element detachably connected to this film can in this case be formed from a different material (eg plastic molding).
  • the packaging according to the invention is designed as a completely closed, preferably flat bag.
  • the two packaging material elements are connected along the entire outer edge of the packaging by a continuous sealing layer or sealing seam.
  • the second packaging material element as an open container, an open hollow body, in particular a bottle, or a thermoformed molding, is formed, depending on the shape and size of the packaged goods.
  • the second packaging material element has a second surface portion, as described above.
  • a thermoformed blister sheet may be used as the second packaging material element;
  • films are known to the person skilled in the art (for example rigid PVC films, cellulose ester films or oriented polystyrene films, in each case with a thickness of 50 to 2000 ⁇ m, more preferably 100 to 1000 ⁇ m).
  • the base area of the packaging can - depending on the size and shape of the packaged goods - have different size and shape; preferred is a rectangular or square shape.
  • the packaging may also be circular, elliptical or irregular in shape.
  • the edges of the package are releasably connected to each other at least two, in particular at least three edges.
  • the two mentioned surface portions of the packaging can be made the same size or different sizes.
  • the cavity for receiving the packaged goods can be divided into several compartments; Likewise, two or more cavities for receiving packaged goods can be provided in each package.
  • the two packaging material elements are constructed of the same material.
  • both packaging material elements may consist of transparent or non-transparent materials.
  • the two packaging material elements are constructed of different materials.
  • one of these elements may be made of transparent material and the other of non-transparent material.
  • At least one of the two packaging material elements preferably the first packaging material element, has a high tear resistance and at the same time a low tear propagation resistance. In this way, a high level of protection against unauthorized opening and a relief of. Handling can be achieved during normal opening.
  • the tear strength be a multiple of the tear propagation resistance.
  • the ratio of tear strength to tear propagation resistance is preferably in the range from 2 to 200, in particular in the range from 50 to 150. The stated values relate to the tear resistance and tear propagation resistance of the two interconnected packaging material elements.
  • Tear strength and tear propagation resistance can be determined by means of known tensile testing machines (eg available from FRANK Eckieri GmbH, D-69488 Birkenau). For example, in such measurements a tear strength of 70 N and a tear strength of 0.5 N was determined; in another case, the tear strength was 95 N and the tear propagation resistance was 1.5 N, measured in each case on the two interconnected packaging material elements which form the packaging. The measurements were carried out on a tensile testing machine from FRANK using a sample holder for tearing tests (type No. 00740).
  • packaging material materials in particular plastic films, which have a different tear propagation resistance in their longitudinal or transverse direction.
  • Said structures, which allow tearing and tearing of the packaging material (s), are preferably applied along the direction of the film in which the tear propagation resistance is lowest.
  • the tearing and tear propagation aids can also be mounted in a different direction than described above.
  • plastic films may be used for this purpose, which were stretched in one direction only, or which were stretched more in the longitudinal direction than in the transverse direction, or vice versa.
  • Such treated films for.
  • polyester films, polystyrene films, polyamide films, polyethylene films or polycarbonate films are known in the art. In this way, the intended Einrei- ⁇ en the packaging material is facilitated without the mechanical stability of the gripping tabs is impaired.
  • the packages according to the invention are preferably characterized in that the packaged goods packed therein are not accessible to children without tools; According to a particularly preferred embodiment, the packages are child resistant according to DIN EN 14375 and / or according to ASTM D3475-03a.
  • the packaging according to the invention can be present as a single package; but it is also intended to combine two or more such packaging, so that a packaging unit is formed, for example in the form of a strip or a card.
  • These interconnected packages may preferably be present in rolled-up form or accordion-folded. It can be provided between the individual connected packaging perforation lines, which allow the separation of a single package. For example, about 50 to 500 such packages may be rolled up in the form of a donor roll around a winding core.
  • Each of the interconnectable, separable packages contains a single dose of a pharmaceutically active agent, and each of these packages has the characteristics of a child-resistant package as described above.
  • two or more individual packages can also be connected to one another in a radial symmetrical arrangement, whereby a packaging unit in the form of a donor disk is formed, from which the individual packages can be separated successively.
  • each of the interconnected separable packages contains a single dose of active ingredient, and each of these packages has the characteristics of child-resistant packaging as described above.
  • packaging units described above are combined with suitable dispensing devices used, which allow or facilitate the separation and removal of the individual packages.
  • first packaging material element and the second packaging material element are formed from different packaging material webs. It can be achieved by folding a single packaging material web that two packaging material elements are available, between which the packaged goods can be positioned.
  • Preferred embodiments of the packaging according to the invention are three-cornered pouches and four-edge pouches.
  • FIG. 1 shows a package (10), which - as shown in the sectional views in the FIG. 2 to 7 is apparent - is formed from a first packaging material element (1) and a second packaging material element (2).
  • the packaging has a first surface section (11), at the edge (21) of which the two packaging material elements (1, 2) are releasably connected to one another; see also FIG. 7 and 8 , Within this first surface section, a cavity (4) for receiving the packaged goods (5) is formed by the two superimposed packaging material elements (see also FIG. 7 and 8 ).
  • the packaging (10) has a second surface section (12) which lies outside or adjoins the first surface section (11) and at the edge or edges (22) of which the two packaging material elements (1, 2) are detachable are interconnected (cf. FIG.
  • This surface portion (12) is formed in a simple manner by protruding packaging material (1, 2) of the first surface portion. Between the first (11) and the second surface portion (12) there is a web (23) in which the two packaging material elements are also detachably connected to each other. Within the second surface portion (12), the packaging is provided with at least one structure (3) - here in the form of a cut - which allows tearing of the / the packaging material element / elements (1, 2).
  • the structure (s) (3) may be in the direction of the line (a) as in FIG FIG. 1 shown attached; Alternatively, they can also be mounted perpendicular thereto, ie in the direction of the line (d), or at an angle.
  • the length and width of the structure (3), as well as their relative position within the surface of the package, may differ from that in FIG. 1 be varied example.
  • the package is bent to open approximately along the line (d).
  • the structure (3) intersects this line at right angles; it runs on both sides of the kink line (d).
  • FIG. 2 how out FIG. 2 can be seen, the two packaging material elements (1, 2) in the region of the second surface portion (12) at their edges (22) connected to each other.
  • the structure (3) is located in the first packaging material element (1) in the immediate vicinity of the sealing edge (22).
  • FIG. 3 shows an alternative embodiment of the in FIG. 1 the package (3) - here in the form of a section - both in the first packaging material element (1) and in the second packaging material element (2) is present, in the same length and at the same position.
  • the two packaging material elements in this case made of different thicknesses materials.
  • FIG. 5 shows an alternative embodiment of the in FIG. 1 shown packaging, wherein the first packaging material element (1) and the second packaging material element (2) made of a single material web, for.
  • the first packaging material element (1) and the second packaging material element (2) made of a single material web, for.
  • As a sheet-like material are formed by the film-shaped material at (24) folded and at the edge (22) is detachably connected, for example by a sealed seam.
  • FIG. 6 shows packaged goods (5), which is enclosed in the cavity (4) of the packaging.
  • the first packaging material element is at the edges or sealing seams (21) releasably connected to the second packaging material element (2).
  • FIG. 7 shows alternative embodiment of in FIG. 1 shown packaging, as a second packaging material element (2) a deep-drawn molding is used.
  • the first packaging material element (1) may be a thermoformed molding, or both packaging material elements (1, 2) may be deep-drawn moldings.
  • FIG. 8th and FIG. 9 illustrate the procedure for the intended opening of in FIG. 1 pictured packaging.
  • the packaging is first folded over along the line (d), as indicated by the semicircular arrow.
  • Line (d) is transverse (ie approximately perpendicular) to the direction of the structure (3) (line (a) in FIG FIG. 1 ), which is designed in the form of a section and in both packaging material elements (1, 2) is present. If the structure (3) runs in a different direction than in FIG. 1 In any case, the direction of kinking is preferably chosen to be approximately perpendicular to the direction of the structure (s) (3) or obliquely thereto.
  • an open notch (25) is formed in the region of the section (3). Due to the low tear strength of the material of the packaging material elements (1, 2), the section (3) by further tearing in the direction of FIG. 8th extended arrows (e) are given.
  • the tear propagation resistance in direction (d) is greater than in the direction of the tear-open structure (3) or in the direction of the line (a) in FIG FIG. 1 ,
  • FIG. 8th sealing edge (22) located at the upper edge of the package are largely or even completely separated.
  • the sealing edge are two exposed edges of the packaging material elements (1, 2), which can serve as Anfbus Anlagenn or gripping tabs and can be pulled apart in the direction of the two arrows.
  • the two packaging material elements (1, 2) can be completely separated from each other, or at least to the area of the packaged goods (5), so that this is accessible and can be removed.
  • FIG. 10 shows a further embodiment of the packaging according to the invention, in which the packaging material elements (1, 2) in the region of the second surface portion (12) along an outer edge by a sealing surface or sealing seam (22) are detachably interconnected.
  • the sealing seam (22) is - as described above - separated, so that the packaging material elements (1, 2) in the surface portion (12) are no longer interconnected, but form individual gripping tabs, by means of which the packaging material elements (1, 2 ) can be completely resolved from each other.
  • FIG. 11 shows structures (3) in the form of a perforation (3a), in the form of a series of successively arranged V-shaped punches (3b), in the form of a diamond-shaped punching (3c); respectively in the direction of in FIG. 1 shown line (a) arranged; and structure (3) in the form of a section (3d) or a perforation (3e), respectively in the direction of in FIG. 1 arranged line (d) arranged; in the case of the structures (3d, 3e), the packaging when opening, for example, in the direction of in FIG. 1 shown line (a) kinked (according to the procedure FIG. 8th and 9 ; see above).
  • FIG. 12 shows a modification of the in FIG. 1 illustrated embodiment, wherein the fold line (d) along an outer edge of the second surface area (12), but extends within this surface area.
  • the tear structure (3) intersects the line (d) at right angles and extends from the Inside of the second surface area (12) into sealed edge area (22 ') inside.
  • FIG. 13 shows a modification of the in FIG. 1 illustrated embodiment, in which the web (23) protrudes in the form of a projection or a tongue in the region of the second surface portion (12).
  • This projection may be trapezoidal, as shown, but it may also be round or convexly curved (eg in the form of a circular segment or parabolic), or in the form of a triangle.
  • the projection can - as shown - be axisymmetric, alternatively, asymmetric or irregular geometric shapes are possible.

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  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Chemical & Material Sciences (AREA)
  • Composite Materials (AREA)
  • Packages (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Bag Frames (AREA)
  • Thermotherapy And Cooling Therapy Devices (AREA)
EP05792509A 2004-09-30 2005-09-10 Nichtwiederverschliessbare verpackung für gesundheits-gefährdende erzeugnisse Active EP1799583B1 (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PL05792509T PL1799583T3 (pl) 2004-09-30 2005-09-10 Nie dające się ponownie zamknąć opakowanie do produktów niebezpiecznych dla zdrowia

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102004047445A DE102004047445B4 (de) 2004-09-30 2004-09-30 Nichtwiederverschließbare Verpackung für gesundheitsgefährdende Erzeugnisse, Verwendung der Verpackung, sowie Verfahren zu deren Herstellung
PCT/EP2005/009748 WO2006037425A1 (de) 2004-09-30 2005-09-10 Nichtwiederverschliessbare verpackung für gesundheits-gefährdende erzeugnisse, sowie verfahren zu deren herstellung

Publications (2)

Publication Number Publication Date
EP1799583A1 EP1799583A1 (de) 2007-06-27
EP1799583B1 true EP1799583B1 (de) 2008-07-23

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Family Applications (1)

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EP05792509A Active EP1799583B1 (de) 2004-09-30 2005-09-10 Nichtwiederverschliessbare verpackung für gesundheits-gefährdende erzeugnisse

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Country Link
US (2) US8307983B2 (no)
EP (1) EP1799583B1 (no)
JP (1) JP4731563B2 (no)
KR (1) KR101194913B1 (no)
CN (1) CN101031480B (no)
AR (1) AR051452A1 (no)
AT (1) ATE402089T1 (no)
AU (1) AU2005291576B2 (no)
BR (1) BRPI0516295B1 (no)
CA (1) CA2580522C (no)
DE (2) DE102004047445B4 (no)
DK (1) DK1799583T3 (no)
ES (1) ES2311235T3 (no)
IL (1) IL182309A0 (no)
IN (1) IN2014DN09063A (no)
MX (1) MX2007003717A (no)
NZ (1) NZ554121A (no)
PL (1) PL1799583T3 (no)
RU (1) RU2357902C2 (no)
TW (1) TWI304042B (no)
WO (1) WO2006037425A1 (no)
ZA (1) ZA200702017B (no)

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US11798436B2 (en) 2019-04-19 2023-10-24 Securikett Ulrich & Horn Gmbh Sealing film

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US7357891B2 (en) 2001-10-12 2008-04-15 Monosol Rx, Llc Process for making an ingestible film
US8900497B2 (en) 2001-10-12 2014-12-02 Monosol Rx, Llc Process for making a film having a substantially uniform distribution of components
US20070281003A1 (en) 2001-10-12 2007-12-06 Fuisz Richard C Polymer-Based Films and Drug Delivery Systems Made Therefrom
US8765167B2 (en) 2001-10-12 2014-07-01 Monosol Rx, Llc Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions
US8603514B2 (en) 2002-04-11 2013-12-10 Monosol Rx, Llc Uniform films for rapid dissolve dosage form incorporating taste-masking compositions
US11207805B2 (en) 2001-10-12 2021-12-28 Aquestive Therapeutics, Inc. Process for manufacturing a resulting pharmaceutical film
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CN101031480A (zh) 2007-09-05
DK1799583T3 (da) 2008-11-17
ATE402089T1 (de) 2008-08-15
BRPI0516295B1 (pt) 2017-11-14
RU2357902C2 (ru) 2009-06-10
DE102004047445A1 (de) 2006-04-13
DE102004047445B4 (de) 2007-05-31
CA2580522A1 (en) 2006-04-13
JP4731563B2 (ja) 2011-07-27
JP2008514517A (ja) 2008-05-08
EP1799583A1 (de) 2007-06-27
RU2007113627A (ru) 2008-10-27
MX2007003717A (es) 2007-05-23
AU2005291576A1 (en) 2006-04-13
IN2014DN09063A (no) 2015-07-10
CN101031480B (zh) 2011-05-25
PL1799583T3 (pl) 2009-01-30
CA2580522C (en) 2013-06-18
BRPI0516295A (pt) 2008-09-02
NZ554121A (en) 2009-11-27
US8307983B2 (en) 2012-11-13
ES2311235T3 (es) 2009-02-01
TWI304042B (en) 2008-12-11
IL182309A0 (en) 2007-07-24
ZA200702017B (en) 2008-04-30
AU2005291576B2 (en) 2011-01-06
TW200616851A (en) 2006-06-01
KR101194913B1 (ko) 2012-10-25
KR20070065416A (ko) 2007-06-22
DE502005004837D1 (de) 2008-09-04
WO2006037425A1 (de) 2006-04-13
US8534461B2 (en) 2013-09-17
US20080105582A1 (en) 2008-05-08
AR051452A1 (es) 2007-01-17
US20130062244A1 (en) 2013-03-14

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