EP1708923B1 - Procede et dispositif de fabrication et de remplissage de recipients - Google Patents

Procede et dispositif de fabrication et de remplissage de recipients Download PDF

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Publication number
EP1708923B1
EP1708923B1 EP04804314A EP04804314A EP1708923B1 EP 1708923 B1 EP1708923 B1 EP 1708923B1 EP 04804314 A EP04804314 A EP 04804314A EP 04804314 A EP04804314 A EP 04804314A EP 1708923 B1 EP1708923 B1 EP 1708923B1
Authority
EP
European Patent Office
Prior art keywords
sterile
filling
hose
filler opening
container
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Not-in-force
Application number
EP04804314A
Other languages
German (de)
English (en)
Other versions
EP1708923A1 (fr
Inventor
Bernd Hansen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to PL04804314T priority Critical patent/PL1708923T3/pl
Publication of EP1708923A1 publication Critical patent/EP1708923A1/fr
Application granted granted Critical
Publication of EP1708923B1 publication Critical patent/EP1708923B1/fr
Not-in-force legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B3/00—Packaging plastic material, semiliquids, liquids or mixed solids and liquids, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, or jars
    • B65B3/02—Machines characterised by the incorporation of means for making the containers or receptacles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B9/00—Enclosing successive articles, or quantities of material, e.g. liquids or semiliquids, in flat, folded, or tubular webs of flexible sheet material; Subdividing filled flexible tubes to form packages
    • B65B9/10—Enclosing successive articles, or quantities of material, in preformed tubular webs, or in webs formed into tubes around filling nozzles, e.g. extruded tubular webs
    • B65B9/24—Enclosing successive articles, or quantities of material, in preformed tubular webs, or in webs formed into tubes around filling nozzles, e.g. extruded tubular webs the tubes being formed in situ by extrusion
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B3/00—Packaging plastic material, semiliquids, liquids or mixed solids and liquids, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, or jars
    • B65B3/04—Methods of, or means for, filling the material into the containers or receptacles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B43/00—Forming, feeding, opening or setting-up containers or receptacles in association with packaging
    • B65B43/02—Forming flat bags from individual sheets or blanks
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B55/00—Preserving, protecting or purifying packages or package contents in association with packaging
    • B65B55/02—Sterilising, e.g. of complete packages
    • B65B55/04—Sterilising wrappers or receptacles prior to, or during, packaging
    • B65B55/10—Sterilising wrappers or receptacles prior to, or during, packaging by liquids or gases
    • B65B55/103—Sterilising flat or tubular webs

Definitions

  • the invention relates to a method for producing and filling containers in which at least one tube of plasticized plastic material is extruded into an open mold, the tube is welded at its leading end when closing the mold to form the container bottom, the tube above the mold is severed to form a filling opening by means of a separating element and the mold is moved with the tube having the open filling opening in a filling position in which the container, after it has been formed by generating a pressure gradient acting on the tube and this widening in the mold , filled and then closed, wherein the filling opening of the tube is at least covered by its formation until filling of the associated container under a sterile room by a sterile barrier.
  • the invention relates to an apparatus for carrying out such a method.
  • bottelpack ® which enable an automated forms (blowing or vacuum molding), filling and closing containers in an economical manner.
  • highly sensitive products are to be placed in the containers,
  • pharmaceuticals that meet international standards for aseptic packaging when placed in the filling position, are in a so-called sterile filling chamber (ASR) in soft sterile air over the open filling opening of the containers flows and provides effective protection against the ingress of germs until, after completion of the filling operation, movable head jaws of the mold are closed to form the desired head closure of the container by a combined vacuum welding operation.
  • ASR sterile filling chamber
  • the open filling opening during the sliding movement of the mold from the extrusion position in which the formed tube is cut under the extruder die and the filling opening is formed is not complete until reaching the filling position protected, even if the process is carried out in a clean room.
  • the hose having the filling opening forms an open-topped container.
  • the known sterile barrier is formed by a heatable plate which is movable together with the dividing element which divides the tube and which is heated to a germicidal temperature, preferably of more than 120 ° C.
  • the movable sterile barrier is in such a position arrangement and provided with such dimensions that, in the working position of the separating element, it is located above the movement path of the mold leading into the filling position and covers the filling opening, until it has reached the filling sterile space.
  • the present invention seeks to further optimize the known solution in terms of improving the sterility in the filling opening of a container to even sterile / sterile in the highly sensitive products for medical / pharmaceutical application To be able to spend containers.
  • This object is achieved by a method having the features of patent claim 1 in its entirety and a device having the features of patent claim 9.
  • Sterile air and / or nitrogen and / or further media, such as other inert gases, hydrogen peroxide, etc., which are brought from the media delivery device to the filling opening, are preferably suitable as sterile media.
  • the medium conveying device with a predeterminable overpressure spend the respective sterile medium in the direction of the filling opening and / or a suction device as part of the media conveyor supports the pertinent conveying direction with negative pressure, wherein the suction device then also excess, sterile medium, from the point of the filling opening to the outside transported away from the molding apparatus, but preferably sucks non-living (non-viable) particles.
  • sterile means such as steam or hydrogen peroxide.
  • the sterilization of the barrier preferably takes place before the respective start-up, but can be initiated at discrete intervals during production breaks.
  • the sterile medium preferably in the form of an inert gas for filling the container can be used, for example, if the product content is sensitive to oxygen.
  • the sterile barrier moves as a plate-shaped cover formed with an inlet and a discharge for the respective sterile medium together with the separator for cutting the plastic tubing or there is a synchronous movement with parts of the manufacturing form.
  • FIGS. 1 and 2 show parts of an apparatus for producing plastic containers in the blow molding process, wherein by means of an extruder 10, a tube 12 of molten plastic material between the two mold halves 14 of a mold 16 is extruded, in the Fig.1a in the open state and in Figs. 1b and 1c is shown in the closed state. After extruding the tube 12 into the opened mold 16, the tube 12 between the nozzle exit of the extruder device 10 and the top of the mold 16 is severed with a knife 28.
  • 1b, 1c show the mold 16 in the closed state, wherein the parts forming the main part of the container to be formed from the tube 12, namely the mold halves 14, have moved together such that bottom welding edges at the lower end of the tube 12 perform a welding operation run to close the hose 12 along a bottom-side weld (not shown).
  • FIG. 1 c shows the mold 16 in a filling position, in which the mold is displaced sideways in relation to the position shown in FIG. 1 a, b and oriented towards the extruder device 10.
  • the container (not shown), which was previously formed by blown through the open filling port 18 by means of a blowing mandrel, not shown, is filled via the filling opening 18 with the respective filling material.
  • 1c shows the end of the filling mandrel 20 to be introduced into the respective filling opening 18 for this purpose. The vertical up and down movement of the filling mandrels 20 in FIG.
  • 1c is represented by a double arrow 22, as is the lateral reciprocating movement of the mold 16 with a double arrow 24 and the possible opening and closing movement of the two mold jaws 14 of the mold 16 with a double arrow 26.
  • the molding and filling of the container by means of a combined blower Filling mandrel done.
  • the mold 16 shown is not limited to the manufacture of one or two containers, but will usually produce a plurality of containers arranged in series next to one another, the simpler representation being explained on the basis of the manufacturing process on only one container.
  • the mold In the filling position shown in Fig. 1c, the mold is below a so-called.
  • Filling sterile room (ASR) which is not shown in detail in the figures and acts as an aseptic shielding of the filling opening 18, which has been formed by the preceding separation process on the tube 12 is.
  • ASR Filling sterile room
  • the Standdorn After filling the container, the Golfdorn is moved upwards and the still open movable upper welding or head jaws (not shown) of the mold 16 are moved together to effect the shaping of the container neck and / or to close this simultaneously by welding.
  • the pertinent production steps are customary in this respect and subject of the already mentioned bottelpack ® system.
  • FIG. 1a shows the operating state prior to cutting through the respective extruded tube 12, wherein serving as a separating element 28 heatable blade is arranged at a predetermined distance and thus also without a gap at the front of a plate-like cover member 30, which serves as a sterile barrier, and Separating element 28 together with cover 30 are reciprocally moved in the directions indicated by double arrow 32, and from a basic position according to Fig.1a in a working position according to Fig.1b and vice versa.
  • a sterile medium 34 can be transported in the direction of the filling opening 18 by means of a medium conveying device designated as a whole by 36.
  • Suitable sterile media 34 are sterile air and / or nitrogen and / or other media, such as other inert gases, hydrogen peroxide, etc., which are brought from the media delivery device 36 to the respective filling opening 18.
  • the plate-shaped cover member 30 in the direction of the filling opening 18 on media discharge points 38 as part of the media conveyor 36, forming a kind of perforation in the plate 30 and the supply of the respective medium via entry points 40 in the direction of Allow filling opening 18 by the pertinent sterile medium 34 is blown in the direction of the filling opening 18.
  • the pertinent entry points 40 which are also part of the media conveyor, are present in the rear region of the cover 30, on the opposite side of the narrow end face of the cover 30 with the separator or knife 28.
  • the sterile medium can be supplied via the sterile barrier to the filling openings.
  • an inert gas for example nitrogen gas
  • this can also be used to keep the container filled with the inert gas, which makes sense, for example, if the product actually to be introduced into the container should be sensitive to oxygen.
  • the media conveying device 36 may have a suction device designated as a whole by 42, preferably in the manner of a vacuum device, which carries out the predetermined removal of the respective sterile medium 34 away from the filling opening 18 with a predeterminable negative pressure via central suction points 44 in the direction of the arrow.
  • the pertinent suction device as part of the media conveyor 36 is mainly used to extract the non-viable particles that are formed at the hose section. In this case, overflowing, sterile medium can be sucked out and brought out of the device. Preferably, there is an equilibrium between the amount of medium that flows out of the perforation by overpressure and the amount of medium that is sucked by the suction device 42.
  • the Abschreibschitzkeit on the central Absaugstellen 44 is shown in the figures with arrows accordingly, and further surrounds the suction or vacuum device 42, the plate-shaped cover 30 like a frame in the form of rectangularly arranged frame members 46, but the rest of the inlet and outlet of the sterile Release the barrier in the form of the cover element 30.
  • the sterile medium is supplied at a temperature which satisfies the sterility conditions, for example by the medium 34 having a temperature of more than 120 ° C, preferably such a temperature in the range of 150 ° C to 200 ° C.
  • the sterile barrier and thus the cover 30, which is preferably constructed of stainless steel materials, be heated to the temperature range mentioned. If the suction device 42 is heated over the sufficient Leia be. If the suction device 42 has the sufficient power potential, the medium 34 need not be supplied via a pump or blower device, but it is sufficient if necessary, the suction to ensure the media management and thus the flow of the respective filling port 18th
  • the closed mold 16 comes to the filling station according to the illustration according to FIG. 1c, whereby here the sterile safety, as already explained, on the Filling sterile room (ASR) is ensured.
  • ASR Filling sterile room
  • the sterile barrier in the form of the covering element 30 is spatially separated from the separating element 28 and can be moved independently of it.
  • the cover member 30 is associated with at least one of the mold halves and, as the illustration in Fig.2b shows, the two mold halves 14 can be moved under the sterile barrier, in which case a synchronous movement between cover 30 and the mold halves 14 vonstatten can go.
  • the sterile barrier in the form of the cover 30 is moved with obvious when moving the mold 16 to the filling station according to the illustration of Fig.2c.
  • the mold moves to the separating element 28 (knife), which cuts thereby and synchronously drives the plate as a sterile barrier (identical to the illustration of FIG. 1).
  • the mold moves with the plate-like cover member 30 in the filling position. Once there, the plate moves backwards, so that the blowing and filling mandrel can enter into the opening 18.
  • After closing the container along its head side then moves the open mold together with the plate as a sterile barrier back into the initial or in the tube position.
  • the separating element 28 is arranged at the same height, but preferably below the covering element 30, in a vertical arrangement.
  • the inventive method is preferably used for the simultaneous production of a plurality of containers, preferably in the form of small-volume containers in the form of ampoules, wherein the formation of the container by blow molding or in particular in very small-volume containers can also be carried out by vacuum molding.

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  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Basic Packing Technique (AREA)
  • Filling Of Jars Or Cans And Processes For Cleaning And Sealing Jars (AREA)
  • Supplying Of Containers To The Packaging Station (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)
  • Constitution Of High-Frequency Heating (AREA)

Claims (11)

  1. Procédé de fabrication et de remplissage de récipients, dans lequel on extrude au moins un tube (12) souple de matière plastique plastifiée dans une moule (16) ouvert, on soude le tube (12) souple à son extrémité en avant lors de la fermeture du moule (16) pour former le fond du récipient, on sépare le tube (12) souple au-dessus du moule pour former une ouverture (18) de remplissage au moyen d'un élément (28) de séparation et on met le moule (16) avec le tube (12) souple ayant l'ouverture (18) de remplissage ouverte en une position de remplissage dans laquelle on remplit ensuite et on ferme le récipient après que celui-ci a été formé dans le moule (16) par production d'un gradient de pression agissant sur le tube (12) souple et l'élargissant, l'ouverture (18) de remplissage du tube (12) souple étant recouverte, au moins de sa formation jusqu'au remplissage du récipient associé dans un espace stérile, par une barrière (30) stérile, caractérisé en ce qu'au moyen de la barrière (30) stérile on apporte au moins un milieu (34) stérile au moyen d'un dispositif (36) de transport de milieu dans la direction de l'ouverture (18) de remplissage.
  2. Procédé suivant la revendication 1, caractérisé en ce que l'on apporte dans le milieu (34) stérile de l'air stérile et/ou d'autres milieux, comme des gaz inertes, du peroxyde d'hydrogène et analogue, par le dispositif (36) de transport de milieu en direction de l'ouverture (18) de remplissage.
  3. Procédé suivant la revendication 1 ou 2, caractérisé en ce que le dispositif (36) de transport de milieu apporte le milieu (34) stérile respectif avec une surpression pouvant être prescrite en direction de l'ouverture (18) de remplissage.
  4. Procédé suivant l'une des revendications 1 à 3, caractérisé en ce que l'on aspire au moyen d'un dispositif (42) d'aspiration, de préférence à la façon d'un dispositif à vide, des particules, notamment non vivantes (non viables).
  5. Procédé suivant l'une des revendications 1 à 4, caractérisé en ce que l'on forme la barrière stérile sous la forme d'un élément (30) de recouvrement en forme de plaque qui, après séparation de tube (12) souple, recouvre l'ouverture (18) de remplissage et est muni d'un milieu (34) stérile jusqu'à ce que le remplissage du récipient soit effectué après son élargissement dans la chambre stérile de remplissage (ASR).
  6. Procédé suivant la revendication 5, caractérisé en ce que l'on déplace l'élément (30) de recouvrement ensemble avec l'élément (28) de séparation pour séparer le tube (12) souple en matière plastique ou en synchronisme avec des parties du moule (16) de manière à ce que, de préférence, l'élément (30) de recouvrement ne dégage l'ouverture (18) de remplissage que lors du remplissage du récipient.
  7. Procédé suivant l'une des revendications 1 à 6, caractérisé en ce que l'on lave au milieu (34) respectif au moyen du dispositif (36) de transport de milieu le récipient par l'ouverture (18) de remplissage puis on l'en emplit partiellement.
  8. Procédé suivant l'une des revendications 1 à 7, caractérisé en ce que la barrière stérile et/ou le milieu (34) stérile peut être chauffé en étant porté, de préférence, à une température supérieure à 120°C, de préférence comprise entre 150°C et 200°C.
  9. Dispositif de fabrication et de remplissage de récipients, comprenant au moins un moule (16) qui a des parois mobiles et dans lequel on peut extruder au moins un tube (12) souple en matière plastique plastifiée, des parties (14) du moule pouvant être fermées pour, par des bords de soudage s'y trouvant, souder l'extrémité en avant du tube (12) souple pour former un fond de récipient, comprenant un dispositif de production d'un gradient de pression agissant sur le film souple et l'élargissant pour former le récipient sur les parois du moule, un élément (28) mobile de séparation qui, peut, pour former une ouverture (18) de remplissage par séparation du tube (12) souple, être déplacé au-dessus du moule, entre une position de base en retrait (Fig. 1a; Fig. 2a) et une position de travail (Fig. 1c; Fig. 2c) et un dispositif de déplacement pour mettre le moule (16) dans une position de remplissage (Fig. 1b; Fig. 2b) pour remplir le récipient par l'ouverture (18) de remplissage, le remplissage du récipient s'effectuant dans une chambre stérile de remplissage (ASR) et l'ouverture (18) de remplissage du tube (12) souple étant recouverte d'une barrière (30) stérile au moins de sa formation jusqu'au remplissage du récipient associé dans la chambre stérile de remplissage (ASR), caractérisé en ce qu'au moyen de la barrière (30) stérile au moins un milieu (34) stérile peut être apporté au moyen d'un dispositif (38) de transport de milieu en direction de l'ouverture (18) de remplissage.
  10. Dispositif suivant la revendication 9, caractérisé en ce que la barrière stérile est sous la forme d'un élément (30) de recouvrement en forme de plaque, qui est muni dans la direction de l'ouverture (18) de remplissage de points (38) de sortie de milieu et ayant au moins un point (40) d'entrée pour l'apport du milieu respectif au moyen d'un dispositif (36) de transport de milieu.
  11. Dispositif suivant la revendication 10, caractérisé en ce qu'il est prévu un dispositif (42) d'aspiration, de préférence sous la forme d'un dispositif à vide, qui entoure à la manière d'un cadre l'élément (30) de recouvrement au moins dans l'une de ses positions et qui fait partie du dispositif (36) de transport de milieu.
EP04804314A 2004-01-30 2004-12-27 Procede et dispositif de fabrication et de remplissage de recipients Not-in-force EP1708923B1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PL04804314T PL1708923T3 (pl) 2004-01-30 2004-12-27 Sposób i urządzenie do wytwarzania i napełniania pojemników

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102004004755A DE102004004755A1 (de) 2004-01-30 2004-01-30 Verfahren und Vorrichtung zum Herstellen und Befüllen von Behältern
PCT/EP2004/014724 WO2005073087A1 (fr) 2004-01-30 2004-12-27 Procede et dispositif de fabrication et de remplissage de recipients

Publications (2)

Publication Number Publication Date
EP1708923A1 EP1708923A1 (fr) 2006-10-11
EP1708923B1 true EP1708923B1 (fr) 2007-06-20

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
EP04804314A Not-in-force EP1708923B1 (fr) 2004-01-30 2004-12-27 Procede et dispositif de fabrication et de remplissage de recipients

Country Status (16)

Country Link
US (1) US8205416B2 (fr)
EP (1) EP1708923B1 (fr)
JP (1) JP4532506B2 (fr)
KR (1) KR101204280B1 (fr)
CN (1) CN100453407C (fr)
AT (1) ATE365129T1 (fr)
AU (1) AU2004314960B2 (fr)
BR (1) BRPI0418489B1 (fr)
CA (1) CA2549648C (fr)
DE (2) DE102004004755A1 (fr)
DK (1) DK1708923T3 (fr)
ES (1) ES2287800T3 (fr)
HK (1) HK1103062A1 (fr)
PL (1) PL1708923T3 (fr)
PT (1) PT1708923E (fr)
WO (1) WO2005073087A1 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102007015078A1 (de) * 2007-03-29 2008-10-02 Bernd Hansen Vorrichtung zum Minimieren des Sauerstoffgehaltes
DE102007040472A1 (de) 2007-08-28 2009-03-05 Bernd Hansen Trennvorrichtung
DE102008006073A1 (de) * 2008-01-25 2009-07-30 Hansen, Bernd, Dipl.-Ing. Vorrichtung zum Herstellen blasgeformter Behältererzeugnisse aus Kunststoffmaterial
DE102008011772A1 (de) 2008-02-28 2009-09-03 Bernd Hansen Trennvorrichtung
DE102008028754A1 (de) * 2008-06-17 2009-12-24 Bernd Hansen Vorrichtung zum Herstellen und Befüllen von Behältern
DE102009031403A1 (de) * 2009-07-01 2011-01-05 Osram Gesellschaft mit beschränkter Haftung Leuchtelement, Leuchte und Verfahren zum Betrieb des Leuchtelements
KR20230079456A (ko) 2017-03-27 2023-06-07 리제너론 파아마슈티컬스, 인크. 살균 방법
DE102021003226A1 (de) * 2021-06-23 2022-12-29 Kocher-Plastik Maschinenbau Gmbh Vorrichtung
DE102021005495A1 (de) 2021-11-06 2023-05-11 Kocher-Plastik Maschinenbau Gmbh Trennvorrichtung
DE102021005494A1 (de) 2021-11-06 2023-05-11 Kocher-Plastik Maschinenbau Gmbh Trennvorrichtung

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2134166A1 (de) 1971-07-09 1973-01-18 Pmd Entwicklungswerk Verfahren und vorrichtung zum herstellen von hohlkoerpern im blas- bzw. blasfuellverfahren
DK154615C (da) * 1976-02-18 1989-05-22 Montedison Spa Fremgangsmaade til fremstilling af hullegemer af to eller flere lag
US4510115A (en) * 1982-11-03 1985-04-09 Baxter Travenol Laboratories, Inc. Method for forming layered thermoplastic articles
JPS6045101A (ja) * 1983-08-06 1985-03-11 アイダエンジニアリング株式会社 合成物質容器成形機のブロ−及び充填回路
JPS6049919A (ja) * 1983-08-30 1985-03-19 Aida Eng Ltd プラスチック容器成形機のブロ−及び注入マンドレルステ−ションの無菌化装置
AT388149B (de) * 1984-01-24 1989-05-10 Broschek G Chem Prod Gebro Verfahren zum automatischen oeffnen von durch zugeschmolzene blastulpen luftdicht verschlossenen kunststoffflaschen und vorrichtung zur durchfuehrung des verfahrens
DE4039040C2 (de) * 1990-12-07 2000-03-23 Merz Verpackungsmaschinen Gmbh Verfahren und Vorrichtung zum Entkeimen der Innenseiten von Folienschläuchen
US5152968A (en) * 1990-12-17 1992-10-06 Elopak Systems A.G. Single pass vapor generation container sterilization system
JPH0649919A (ja) * 1992-07-28 1994-02-22 Haseko Corp 断熱内装パネル及びこれを利用した内装構造
US5862840A (en) 1994-03-21 1999-01-26 Hansen; Bernd Device for sterile filling of containers
US5872359A (en) * 1995-07-27 1999-02-16 American Sterilizer Company Real-time monitor and control system and method for hydrogen peroxide vapor decontamination
JPH10119934A (ja) * 1996-10-23 1998-05-12 Shikoku Kakoki Co Ltd 容器殺菌装置および容器包材の殺菌方法
US5792435A (en) * 1997-04-08 1998-08-11 Steris Corporation Vapor phase decontaminant isolator apparatus with integral vapor phase decontaminant generator system
US6098676A (en) 1998-02-10 2000-08-08 Vital Signs Inc. Aseptic liquid fillings
DE10063282C2 (de) * 2000-12-19 2003-06-18 Bernd Hansen Verfahren und Vorrichtung zum Herstellen und Befüllen von Behältern
ES2243717T3 (es) * 2001-02-16 2005-12-01 Steris Inc. Descontaminacion en fase de vapor de contenedores.
WO2006121815A2 (fr) * 2005-05-06 2006-11-16 Uniloy Milacron Inc. Procede et appareil de moulage par soufflage pour recipients aseptiques

Also Published As

Publication number Publication date
BRPI0418489B1 (pt) 2016-12-13
AU2004314960A1 (en) 2005-08-11
ATE365129T1 (de) 2007-07-15
KR20060130143A (ko) 2006-12-18
CN1906088A (zh) 2007-01-31
PL1708923T3 (pl) 2007-11-30
DE502004004159D1 (de) 2007-08-02
DK1708923T3 (da) 2007-10-29
WO2005073087A1 (fr) 2005-08-11
HK1103062A1 (en) 2007-12-14
CN100453407C (zh) 2009-01-21
PT1708923E (pt) 2007-07-12
AU2004314960B2 (en) 2010-05-13
DE102004004755A1 (de) 2005-08-25
EP1708923A1 (fr) 2006-10-11
ES2287800T3 (es) 2007-12-16
KR101204280B1 (ko) 2012-11-27
US20080041019A1 (en) 2008-02-21
CA2549648C (fr) 2011-05-31
JP4532506B2 (ja) 2010-08-25
CA2549648A1 (fr) 2005-08-11
US8205416B2 (en) 2012-06-26
BRPI0418489A (pt) 2007-06-19
JP2007519575A (ja) 2007-07-19

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