EP1603537A4 - NOVEL FORMULATION, ANTICIPATED COMPLEX IMMEDIATE RELEASE FOR A FAST AND CONTINUOUS SUPPRESSION OF MAGIC ACID - Google Patents

NOVEL FORMULATION, ANTICIPATED COMPLEX IMMEDIATE RELEASE FOR A FAST AND CONTINUOUS SUPPRESSION OF MAGIC ACID

Info

Publication number
EP1603537A4
EP1603537A4 EP04713382A EP04713382A EP1603537A4 EP 1603537 A4 EP1603537 A4 EP 1603537A4 EP 04713382 A EP04713382 A EP 04713382A EP 04713382 A EP04713382 A EP 04713382A EP 1603537 A4 EP1603537 A4 EP 1603537A4
Authority
EP
European Patent Office
Prior art keywords
antacidal
omeprazole
rapid
complex
immediate release
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP04713382A
Other languages
German (de)
English (en)
French (fr)
Other versions
EP1603537A2 (en
Inventor
Bonnie Hepburn
Barry Goldlust
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Santarus Inc
University of Missouri Columbia
Original Assignee
Santarus Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Santarus Inc filed Critical Santarus Inc
Publication of EP1603537A2 publication Critical patent/EP1603537A2/en
Publication of EP1603537A4 publication Critical patent/EP1603537A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EP04713382A 2003-02-20 2004-02-20 NOVEL FORMULATION, ANTICIPATED COMPLEX IMMEDIATE RELEASE FOR A FAST AND CONTINUOUS SUPPRESSION OF MAGIC ACID Withdrawn EP1603537A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US44862703P 2003-02-20 2003-02-20
US448627P 2003-02-20
PCT/US2004/005170 WO2004073654A2 (en) 2003-02-20 2004-02-20 A novel formulation, omeprazole antacid complex-immediate release for rapid and sustained supression of gastric acid

Publications (2)

Publication Number Publication Date
EP1603537A2 EP1603537A2 (en) 2005-12-14
EP1603537A4 true EP1603537A4 (en) 2009-11-04

Family

ID=32908619

Family Applications (1)

Application Number Title Priority Date Filing Date
EP04713382A Withdrawn EP1603537A4 (en) 2003-02-20 2004-02-20 NOVEL FORMULATION, ANTICIPATED COMPLEX IMMEDIATE RELEASE FOR A FAST AND CONTINUOUS SUPPRESSION OF MAGIC ACID

Country Status (7)

Country Link
US (1) US20040248942A1 (https=)
EP (1) EP1603537A4 (https=)
JP (1) JP2006518751A (https=)
AR (1) AR043258A1 (https=)
CA (1) CA2517005A1 (https=)
TW (1) TWI367759B (https=)
WO (1) WO2004073654A2 (https=)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050220870A1 (en) * 2003-02-20 2005-10-06 Bonnie Hepburn Novel formulation, omeprazole antacid complex-immediate release for rapid and sustained suppression of gastric acid
CA2531564C (en) * 2003-07-18 2016-01-19 Santarus, Inc. Pharmaceutical composition for inhibiting acid secretion
US8993599B2 (en) * 2003-07-18 2015-03-31 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
WO2005007117A2 (en) * 2003-07-18 2005-01-27 Santarus, Inc. Pharmaceutical formulation and method for treating acid-caused gastrointestinal disorders
EP1718303A4 (en) * 2004-02-10 2010-09-01 Santarus Inc COMBINATION OF INHIBITOR OF PROTON PUMP, BUFFER AND NON-STEROIDAL ANTI-INFLAMMATORY DRUG
GB0403165D0 (en) * 2004-02-12 2004-03-17 Ct Novel uses for proton pump inhibitors
US8815916B2 (en) * 2004-05-25 2014-08-26 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US8906940B2 (en) 2004-05-25 2014-12-09 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US7576216B2 (en) 2004-07-30 2009-08-18 Abbott Laboratories Preparation of pyridonecarboxylic acid antibacterials
WO2006110815A1 (en) * 2005-04-11 2006-10-19 Abbott Laboratories Pharmaceutical compositions having improved dissolution profiles for poorly soluble drugs
RU2468800C2 (ru) * 2005-04-12 2012-12-10 Сукампо Аг Комбинированное применение производного простагландина и ингибитора протонового насоса для лечения желудочно-кишечных заболеваний
US20060276500A1 (en) * 2005-04-26 2006-12-07 Phillips Jeffrey O Compositions and methods for treating nocturnal acid breakthrough and other acid related disorders
US7803817B2 (en) * 2005-05-11 2010-09-28 Vecta, Ltd. Composition and methods for inhibiting gastric acid secretion
US7981908B2 (en) * 2005-05-11 2011-07-19 Vecta, Ltd. Compositions and methods for inhibiting gastric acid secretion
AU2006283702A1 (en) * 2005-08-19 2007-03-01 Aventis Pharmaceuticals Inc. Comination of a hypnotic agent and R(+)-alpha-(2,3-dimethoxy-phenyl)-1-(2-(4-fluorophenl)ethyl)-4-piperidinemethanol and therapeutic application thereof
CA2634637A1 (en) * 2005-12-28 2007-07-05 Takeda Pharmaceutical Company Limited Controlled release solid preparation
US20090175959A1 (en) * 2005-12-28 2009-07-09 Takeda Pharmaceutical Company Limited Controlled Release Solid Preparation
US8512761B2 (en) * 2006-01-27 2013-08-20 Yale University Fast acting inhibitor of gastric acid secretion
US11510894B2 (en) * 2006-01-27 2022-11-29 John P. Geibel Fast acting inhibitor of gastric acid secretion
ES2281292B1 (es) * 2006-03-08 2008-06-16 Quimica Sintetica S.A. Nuevas sales de esomeprazol. procedimiento de preparacion y composiciones farmaceuticas que las comprenden.
WO2008002567A2 (en) * 2006-06-27 2008-01-03 Alza Corporation Methods of treating conditions by sustained release administration of benzimidazole derivatives
EP1880716A1 (en) * 2006-07-19 2008-01-23 Sandoz AG Kit of parts comprising an acid labile and an acid resistant pharmaceutically active ingredient
PL2046334T3 (pl) * 2006-07-25 2015-02-27 Vecta Ltd Kompozycje i sposoby hamowania wydzielania kwasów żołądkowych z wykorzystaniem pochodnych małych kwasów dikarboksylowych w połączeniu z PPI
WO2008016887A2 (en) * 2006-07-29 2008-02-07 Graceway Pharmaceuticals, Llc Methods and pharmaceutical compositions to treat gastric acid disorders
EP2086543A2 (en) 2006-10-27 2009-08-12 The Curators of the University of Missouri Compositions comprising at least one acid labile proton pump inhibiting agents, optionally other pharmaceutically active agents and methods of using same
US20080166423A1 (en) * 2007-01-06 2008-07-10 Renjit Sundharadas Combination Medication for Treating the Effects of Stomach Acid Reduction Medication on Bone Integrity
JP2011512416A (ja) 2008-02-20 2011-04-21 ザ・キュレイターズ・オブ・ザ・ユニバーシティー・オブ・ミズーリ オメプラゾール及びランソプラゾールの組合せと緩衝剤を含んでなる組成物とそれを使用する方法
AU2010266026B2 (en) * 2009-06-25 2014-08-07 Nuvo Pharmaceuticals (Ireland) Designated Activity Company Method for treating a patient in need of aspirin therapy
JP2013511522A (ja) * 2009-11-23 2013-04-04 イーグル・ファーマシューティカルズ・インコーポレーテッド ダプトマイシン製剤
WO2012106058A2 (en) 2011-01-31 2012-08-09 New Market Pharmaceuticals Animal treatments
EP2827847B1 (en) 2012-03-21 2022-09-14 Galleon Labs LLC Topically administered strontium-containing complexes for treating pain, pruritis and inflammation
WO2013165468A1 (en) 2012-05-02 2013-11-07 New Market Pharmaceuticals Pharmaceutical compositions for direct systemic introduction
US20160250253A1 (en) * 2013-09-24 2016-09-01 Cosmederm Bioscience, Inc. Strontium-containing complexes for treating gastroesophageal reflux and barrett's esophagus
JP6443891B2 (ja) * 2014-01-31 2018-12-26 塩野義製薬株式会社 徐放性製剤
US11590165B2 (en) * 2014-12-17 2023-02-28 Bausch Health Companies Inc. Formulations of calcium and phosphate for oral inflammation
WO2016174664A1 (en) 2015-04-29 2016-11-03 Dexcel Pharma Technologies Ltd. Orally disintegrating compositions
US11235002B2 (en) 2015-08-21 2022-02-01 Galleon Labs Llc Strontium based compositions and formulations for pain, pruritus, and inflammation
US10076494B2 (en) 2016-06-16 2018-09-18 Dexcel Pharma Technologies Ltd. Stable orally disintegrating pharmaceutical compositions
KR102608889B1 (ko) * 2020-07-14 2023-12-04 한미약품 주식회사 프로톤 펌프 저해제 및 제산제를 포함하는 약제학적 복합제제 및 그의 제조방법
KR102276547B1 (ko) * 2020-09-04 2021-07-13 주식회사유한양행 오메프라졸, 에스오메프라졸 또는 이의 약제학적으로 허용가능한 염을 포함하는 정제 형태의 약학 조성물 및 이의 제조방법
CN111870583B (zh) * 2020-09-28 2020-12-18 上海翰森生物医药科技有限公司 一种注射用艾司奥美拉唑钠冻干制剂及其制备方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020045646A1 (en) * 1996-01-04 2002-04-18 Phillips Jeffrey O. Novel substituted benzimidazole dosage forms and method of using same
US6489346B1 (en) * 1996-01-04 2002-12-03 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
WO2003061584A2 (en) * 2002-01-19 2003-07-31 The Curators Of The University Of Missouri Novel substituted benzimidazole dosage forms and method of using same

Family Cites Families (84)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4045564A (en) * 1974-02-18 1977-08-30 Ab Hassle Benzimidazole derivatives useful as gastric acid secretion inhibitors
IN148930B (https=) * 1977-09-19 1981-07-25 Hoffmann La Roche
SE7804231L (sv) * 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
US4472409A (en) * 1981-11-05 1984-09-18 Byk Gulden Lomberg Chemische Fabrik Gesellschaft Mit Beschrankter Haftung 2-Pyridylmethyl thio(sulfinyl)benzimidazoles with gastric acid secretion inhibiting effects
SE8300736D0 (sv) * 1983-02-11 1983-02-11 Haessle Ab Novel pharmacologically active compounds
SE8301182D0 (sv) * 1983-03-04 1983-03-04 Haessle Ab Novel compounds
SE8403179D0 (sv) * 1984-06-13 1984-06-13 Haessle Ab New compounds
US5246714A (en) * 1985-10-11 1993-09-21 Aktiebolaget Hassle Drug preparation
US5433959A (en) * 1986-02-13 1995-07-18 Takeda Chemical Industries, Ltd. Stabilized pharmaceutical composition
CA1327010C (en) * 1986-02-13 1994-02-15 Tadashi Makino Stabilized solid pharmaceutical composition containing antiulcer benzimidazole compound and its production
GB2189699A (en) * 1986-04-30 1987-11-04 Haessle Ab Coated acid-labile medicaments
SE8604566D0 (sv) * 1986-10-27 1986-10-27 Haessle Ab Novel compunds
US5026560A (en) * 1987-01-29 1991-06-25 Takeda Chemical Industries, Ltd. Spherical granules having core and their production
NZ224252A (en) * 1987-04-21 1991-09-25 Erba Carlo Spa An anthracycline glycoside and its preparation
GB8809421D0 (en) * 1988-04-21 1988-05-25 Fordonal Sa Antacid compositions with prolonged gastric residence time
JPH03505450A (ja) * 1988-06-30 1991-11-28 ジ・アップジョン・カンパニー 胃腸病用の経皮抗分泌剤
SE8804629D0 (sv) * 1988-12-22 1988-12-22 Ab Haessle New therapeutically active compounds
SE8804628D0 (sv) * 1988-12-22 1988-12-22 Ab Haessle New compounds
IE64199B1 (en) * 1988-12-22 1995-07-12 Haessle Ab Compound with gastric acid inhibitory effect and process for its preparation
JP2694361B2 (ja) * 1989-02-09 1997-12-24 アストラ アクチエボラグ 抗菌剤
DE69014141T2 (de) * 1989-02-10 1995-05-24 Takeda Chemical Industries Ltd Verwendung von Benzimidazol-Derivaten als antibakterielle Mittel.
SE8903563D0 (sv) * 1989-10-26 1989-10-26 Haessle Ab A novel dissolution system
US5204118A (en) * 1989-11-02 1993-04-20 Mcneil-Ppc, Inc. Pharmaceutical compositions and methods for treating the symptoms of overindulgence
KR930000861B1 (ko) * 1990-02-27 1993-02-08 한미약품공업 주식회사 오메프라졸 직장투여 조성물
SE9002043D0 (sv) * 1990-06-07 1990-06-07 Astra Ab Improved method for synthesis
DE69131627T2 (de) * 1990-06-20 2000-04-27 Astra Ab Soedertaelje Dialkoxypyridinylbenzimidazolderivate, verfahren zur herstellung und ihre pharmazeutische verwendung
US5232706A (en) * 1990-12-31 1993-08-03 Esteve Quimica, S.A. Oral pharmaceutical preparation containing omeprazol
US5215874A (en) * 1991-01-21 1993-06-01 Fuji Photo Film Co., Ltd. Silver halide photographic material having magnetic recording member
US5244670A (en) * 1991-04-04 1993-09-14 The Procter & Gamble Company Ingestible pharmaceutical compositions for treating upper gastrointestinal tract distress
WO1993006097A1 (en) * 1991-09-20 1993-04-01 Merck & Co., Inc. Novel process for the preparation of anti-ulcer agents
TW224049B (https=) * 1991-12-31 1994-05-21 Sunkyong Ind Ltd
TW276996B (https=) * 1992-04-24 1996-06-01 Astra Ab
US5504082A (en) * 1992-06-01 1996-04-02 Yoshitomi Pharmaceutical Industries, Ltd. Pyridine compound and pharmaceutical compostions
FR2692146B1 (fr) * 1992-06-16 1995-06-02 Ethypharm Sa Compositions stables de microgranules d'omeprazole gastro-protégés et leur procédé d'obtention.
US5447918A (en) * 1992-07-27 1995-09-05 Mccullough; Ricky W. Gastrointestinal anti-irritant composition comprising sucralfate and methods of use
SE9301489D0 (sv) * 1993-04-30 1993-04-30 Ab Astra Veterinary composition
SE9301830D0 (sv) * 1993-05-28 1993-05-28 Ab Astra New compounds
US5877192A (en) * 1993-05-28 1999-03-02 Astra Aktiebolag Method for the treatment of gastric acid-related diseases and production of medication using (-) enantiomer of omeprazole
SE9302396D0 (sv) * 1993-07-09 1993-07-09 Ab Astra A novel compound form
CA2128820A1 (en) * 1993-07-27 1995-01-28 Walter G. Gowan, Jr. Rapidly disintegrating pharmaceutical dosage form and process for preparation thereof
EP0995447A1 (en) * 1993-09-09 2000-04-26 Takeda Chemical Industries, Ltd. Formulation comprising antibacterial substance and antiulcer substance
US5935600A (en) * 1993-09-10 1999-08-10 Fuisz Technologies Ltd. Process for forming chewable quickly dispersing comestible unit and product therefrom
AU7833194A (en) * 1993-09-20 1995-04-10 Procter & Gamble Company, The Use of triclosan phosphates for the treatment of gastrointestinal disorders due to heliobacter infection
WO1995010264A1 (en) * 1993-10-12 1995-04-20 Tokyo Tanabe Company Limited Tablet containing enteric granules
TW280770B (https=) * 1993-10-15 1996-07-11 Takeda Pharm Industry Co Ltd
US5714505A (en) * 1994-01-05 1998-02-03 Astra Aktiebolag Method for treatment of psoriasis, by omeprazole or related compounds
SE9402431D0 (sv) * 1994-07-08 1994-07-08 Astra Ab New tablet formulation
GB2290965A (en) * 1994-07-11 1996-01-17 Therapicon Srl Multiple layer capsules for drugs
SE504459C2 (sv) * 1994-07-15 1997-02-17 Astra Ab Förfarande för framställning av substituerade sulfoxider
GB9423968D0 (en) * 1994-11-28 1995-01-11 Astra Ab Resolution
US5628981A (en) * 1994-12-30 1997-05-13 Nano Systems L.L.C. Formulations of oral gastrointestinal diagnostic x-ray contrast agents and oral gastrointestinal therapeutic agents
SE9500478D0 (sv) * 1995-02-09 1995-02-09 Astra Ab New pharmaceutical formulation and process
HRP960232A2 (en) * 1995-07-03 1998-02-28 Astra Ab A process for the optical purification of compounds
US5945124A (en) * 1995-07-05 1999-08-31 Byk Gulden Chemische Fabrik Gmbh Oral pharmaceutical composition with delayed release of active ingredient for pantoprazole
NZ319673A (en) * 1995-10-17 2000-06-23 Astra Pharma Prod Quinazoline compounds for inflammatory disorders such rheumatoid arthritis or osteoarthritis
US20050054682A1 (en) * 1996-01-04 2005-03-10 Phillips Jeffrey O. Pharmaceutical compositions comprising substituted benzimidazoles and methods of using same
SE9600071D0 (sv) * 1996-01-08 1996-01-08 Astra Ab New oral formulation of two active ingredients I
US6169102B1 (en) * 1996-06-25 2001-01-02 Takeda Chemical Industries, Ltd. Oxazolone derivatives and their use as anti-Helicobacter pylori agent
US5766622A (en) * 1996-08-14 1998-06-16 The Procter & Gamble Company Inhibiting undesirable taste in oral compositions
CA2262595C (en) * 1996-08-15 2005-10-18 Losan Pharma Gmbh Easy to swallow oral medicament composition
US5885594A (en) * 1997-03-27 1999-03-23 The Procter & Gamble Company Oral compositions having enhanced mouth-feel
US5939091A (en) * 1997-05-20 1999-08-17 Warner Lambert Company Method for making fast-melt tablets
TW580397B (en) * 1997-05-27 2004-03-21 Takeda Chemical Industries Ltd Solid preparation
SE9702000D0 (sv) * 1997-05-28 1997-05-28 Astra Ab New pharmaceutical formulation
ATE500815T1 (de) * 1997-12-08 2011-03-15 Dietrich Rango Neue suppositoriumsform mit säureempfindlichem wirkstoff
US6365180B1 (en) * 1998-01-20 2002-04-02 Glenn A. Meyer Oral liquid compositions
FR2774288B1 (fr) * 1998-01-30 2001-09-07 Ethypharm Sa Microgranules d'omeprazole gastroproteges, procede d'obtention et preparations pharmaceutiques
CA2298823C (en) * 1998-04-20 2011-06-07 Eisai Co., Ltd. Stabilized composition comprising a benzimidazole type compound
US6047829A (en) * 1998-09-18 2000-04-11 Westvaco Corporation Unit dose packaging system (UDPS) having a child resistant locking feature
US6294192B1 (en) * 1999-02-26 2001-09-25 Lipocine, Inc. Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents
US6248363B1 (en) * 1999-11-23 2001-06-19 Lipocine, Inc. Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
US7111317B1 (en) * 2000-03-24 2006-09-19 Eastman Kodak Company Method for providing image goods and/or services to a customer
US6740339B1 (en) * 1999-06-18 2004-05-25 Takeda Chemical Industries, Ltd. Quickly disintegrating solid preparations
US6555139B2 (en) * 1999-06-28 2003-04-29 Wockhardt Europe Limited Preparation of micron-size pharmaceutical particles by microfluidization
US7678387B2 (en) * 2000-06-06 2010-03-16 Capricorn Pharma, Inc. Drug delivery systems
US20020044962A1 (en) * 2000-06-06 2002-04-18 Cherukuri S. Rao Encapsulation products for controlled or extended release
US6572900B1 (en) * 2000-06-09 2003-06-03 Wm. Wrigley, Jr. Company Method for making coated chewing gum products including a high-intensity sweetener
WO2003000235A1 (en) * 2001-06-22 2003-01-03 Pfizer Products Inc. Pharmaceutical compositions of dispersions of drugs and neutral polymers
US20030050620A1 (en) * 2001-09-07 2003-03-13 Isa Odidi Combinatorial type controlled release drug delivery device
US20040146559A1 (en) * 2002-09-28 2004-07-29 Sowden Harry S. Dosage forms having an inner core and outer shell with different shapes
US20030091630A1 (en) * 2001-10-25 2003-05-15 Jenny Louie-Helm Formulation of an erodible, gastric retentive oral dosage form using in vitro disintegration test data
FR2832311B1 (fr) * 2001-11-21 2004-04-16 Besins Int Belgique Poudre filmogene, compositions la comprenant, leurs procedes de preparation et leurs utilisations
CA2531564C (en) * 2003-07-18 2016-01-19 Santarus, Inc. Pharmaceutical composition for inhibiting acid secretion
US8062664B2 (en) * 2003-11-12 2011-11-22 Abbott Laboratories Process for preparing formulations of lipid-regulating drugs

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020045646A1 (en) * 1996-01-04 2002-04-18 Phillips Jeffrey O. Novel substituted benzimidazole dosage forms and method of using same
US6489346B1 (en) * 1996-01-04 2002-12-03 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
US20030191159A1 (en) * 1996-01-04 2003-10-09 Phillips Jeffrey O. Novel substituted benzimidazole dosage forms and method of using same
WO2003061584A2 (en) * 2002-01-19 2003-07-31 The Curators Of The University Of Missouri Novel substituted benzimidazole dosage forms and method of using same

Also Published As

Publication number Publication date
AR043258A1 (es) 2005-07-20
JP2006518751A (ja) 2006-08-17
CA2517005A1 (en) 2004-09-02
EP1603537A2 (en) 2005-12-14
TWI367759B (en) 2012-07-11
TW200509923A (en) 2005-03-16
WO2004073654A2 (en) 2004-09-02
WO2004073654A3 (en) 2005-01-13
US20040248942A1 (en) 2004-12-09

Similar Documents

Publication Publication Date Title
EP1603537A4 (en) NOVEL FORMULATION, ANTICIPATED COMPLEX IMMEDIATE RELEASE FOR A FAST AND CONTINUOUS SUPPRESSION OF MAGIC ACID
EP1796641A4 (en) NEW FORMULATION, OMEPRAZOL ANTAZIDA COMPLEX WITH IMMEDIATE RELEASE FOR THE RAPID AND CONTINUOUS SUPPRESSION OF MAGIC ACID
EP1718282A4 (en) PROCESS AND COMPOSITIONS FOR IMAGE PRESENTATION
EP1573086A4 (en) ADDITIVES FOR PREVENTING THE DEGRADATION OF ALKYL HYDROGEN SILOXANES
EP1715853A4 (en) COMPOSITIONS FOR THE DISTRIBUTION OF HYPNOTICS IN THE FIELD OF MUNICHCHLEIMHÄUTE AND USE METHOD THEREOF
NO20035632D0 (no) Selv-emulgerende formuleringer av kolesterylester- overföringsproteininhibitorer
EP1827604A4 (en) METHOD AND COMPOSITIONS FOR ADOPTIVE IMMUNOTHERAPY
FR2857200B1 (fr) Processeur video pour l'endoscopie
EP1752150A4 (en) Irinotecan PREPARATION
DE60111430D1 (de) Hypochlorige säure zusammensetzung und ihre verwendungen
EP1648474A4 (en) PROCESS AND PHARMACEUTICAL COMPOSITIONS FOR WOUND HEALING
EP1736263A4 (en) CLAMPING STRUCTURE FOR DISPOSABLE TIP
EP1979269A4 (en) CHLORINE FORMULATIONS AND PROCESS FOR THE PREPARATION AND USE THEREOF
DE60121951D1 (de) Charakterisierung nichtlinearen Verhaltens
EP1722821A4 (en) COMPOSITION FOR THE ORAL ADMINISTRATION OF TAMSULOSINE HYDROCHLORIDE AND THIS CONTAINING GRANULATE FORMULATION WITH CONTROLLED RELEASE
DE60210446D1 (de) Zusammensetzungen enthaltend einen alpha-2-adrenorezeptoragonisten und eine fettsaeure
EP1576109A4 (en) METHOD AND COMPOSITIONS FOR CATEGORIZING PATIENTS
IL179336A0 (en) Benzoic acid derivatives and pharmaceutical compositions containing the same
IL174248A0 (en) Alkyl carboxylic acid derivatives and pharmaceutical compositions containing the same
EP1838289A4 (en) CONTROLLED RELEASE OF BIOLOGICAL UNITS
FR2879931B1 (fr) Materiau silicone pour la liberation d'une molecule active
EP1755477A4 (en) MOUTH HYGIENE COMPOSITIONS AND METHOD OF USE THEREOF
EP1411897A4 (en) COMPOSITIONS AND METHODS FOR INTRA-CELLULAR DELIVERY
NO20033356D0 (no) Fremgangsmåte for fremstilling av DTPA-monoamider
ITMI20040013A1 (it) Procedimento per la preparazione di esteri dell'acido -met-acrilico

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20050920

AK Designated contracting states

Kind code of ref document: A2

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR

AX Request for extension of the european patent

Extension state: AL LT LV MK

DAX Request for extension of the european patent (deleted)
A4 Supplementary search report drawn up and despatched

Effective date: 20091001

RIC1 Information provided on ipc code assigned before grant

Ipc: A61K 33/10 20060101ALI20090925BHEP

Ipc: A61P 1/04 20060101ALI20090925BHEP

Ipc: A61K 31/4439 20060101ALI20090925BHEP

Ipc: A61K 9/48 20060101ALI20090925BHEP

Ipc: A61K 9/42 20060101ALI20090925BHEP

Ipc: A61K 9/30 20060101ALI20090925BHEP

Ipc: A61K 9/28 20060101ALI20090925BHEP

Ipc: A61K 9/26 20060101ALI20090925BHEP

Ipc: A61K 9/24 20060101ALI20090925BHEP

Ipc: A61K 9/20 20060101ALI20090925BHEP

Ipc: A61K 9/16 20060101ALI20090925BHEP

Ipc: A61K 9/14 20060101AFI20050125BHEP

RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: SANTARUS, INC.

RIN1 Information on inventor provided before grant (corrected)

Inventor name: PHILLIPS, JEFFREY OWEN

Inventor name: GOLDLUST, BARRY

Inventor name: HEPBURN, BONNIE

RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: THE CURATORS OF THE UNIVERSITY OF MISSOURI

Owner name: SANTARUS, INC.

17Q First examination report despatched

Effective date: 20110413

RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: THE CURATORS OF THE UNIVERSITY OF MISSOURI

Owner name: SANTARUS, INC.

111L Licence recorded

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LU MC NL PT RO SE SI SK

Free format text: EXCLUSIVE LICENSE

Name of requester: NORGINE BV, NL

Effective date: 20111115

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LU MC NL PT RO SE SI SK TR

Free format text: EXCLUSIVE LICENSE

Name of requester: SANTARUS, INC., US

Effective date: 20111115

TPAC Observations filed by third parties

Free format text: ORIGINAL CODE: EPIDOSNTIPA

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20190903