EP1578779A4 - Erythropoietinrezeptor-bindende antikörper - Google Patents

Erythropoietinrezeptor-bindende antikörper

Info

Publication number
EP1578779A4
EP1578779A4 EP03774776A EP03774776A EP1578779A4 EP 1578779 A4 EP1578779 A4 EP 1578779A4 EP 03774776 A EP03774776 A EP 03774776A EP 03774776 A EP03774776 A EP 03774776A EP 1578779 A4 EP1578779 A4 EP 1578779A4
Authority
EP
European Patent Office
Prior art keywords
receptor binding
binding antibodies
erythropoietin receptor
erythropoietin
antibodies
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP03774776A
Other languages
English (en)
French (fr)
Other versions
EP1578779A2 (de
Inventor
Peter J Devries
Larry L Green
David H Ostrow
Edward B Reilly
James Wieler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/269,711 external-priority patent/US20040071694A1/en
Priority claimed from US10/684,109 external-priority patent/US7396913B2/en
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Publication of EP1578779A2 publication Critical patent/EP1578779A2/de
Publication of EP1578779A4 publication Critical patent/EP1578779A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/74—Inducing cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
EP03774776A 2002-10-14 2003-10-14 Erythropoietinrezeptor-bindende antikörper Withdrawn EP1578779A4 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US269711 2002-10-14
US10/269,711 US20040071694A1 (en) 2002-10-14 2002-10-14 Erythropoietin receptor binding antibodies
US684109 2003-10-10
US10/684,109 US7396913B2 (en) 2002-10-14 2003-10-10 Erythropoietin receptor binding antibodies
PCT/US2003/032243 WO2004035603A2 (en) 2002-10-14 2003-10-14 Erythropoietin receptor binding antibodies

Publications (2)

Publication Number Publication Date
EP1578779A2 EP1578779A2 (de) 2005-09-28
EP1578779A4 true EP1578779A4 (de) 2011-11-16

Family

ID=32109805

Family Applications (1)

Application Number Title Priority Date Filing Date
EP03774776A Withdrawn EP1578779A4 (de) 2002-10-14 2003-10-14 Erythropoietinrezeptor-bindende antikörper

Country Status (13)

Country Link
EP (1) EP1578779A4 (de)
JP (2) JP4411472B2 (de)
KR (1) KR20050059263A (de)
CN (1) CN103524618A (de)
AU (2) AU2003282588B2 (de)
BR (1) BR0315275A (de)
CA (1) CA2501984C (de)
MX (1) MXPA05003997A (de)
NZ (1) NZ539263A (de)
PL (1) PL379985A1 (de)
TW (1) TWI320716B (de)
WO (1) WO2004035603A2 (de)
ZA (1) ZA201004902B (de)

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Also Published As

Publication number Publication date
WO2004035603A2 (en) 2004-04-29
MXPA05003997A (es) 2005-06-22
AU2010214778A1 (en) 2010-09-23
CA2501984A1 (en) 2004-04-29
AU2003282588A1 (en) 2004-05-04
NZ539263A (en) 2009-07-31
JP2009149665A (ja) 2009-07-09
JP4411472B2 (ja) 2010-02-10
ZA201004902B (en) 2012-06-27
TW200418505A (en) 2004-10-01
JP2006523083A (ja) 2006-10-12
CN103524618A (zh) 2014-01-22
EP1578779A2 (de) 2005-09-28
KR20050059263A (ko) 2005-06-17
PL379985A1 (pl) 2006-11-27
WO2004035603A3 (en) 2006-04-27
BR0315275A (pt) 2005-08-30
TWI320716B (en) 2010-02-21
CA2501984C (en) 2011-04-26
AU2003282588B2 (en) 2010-06-03

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