EP1514600A1 - Mechanische Kolbenpipette - Google Patents

Mechanische Kolbenpipette Download PDF

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Publication number
EP1514600A1
EP1514600A1 EP03405604A EP03405604A EP1514600A1 EP 1514600 A1 EP1514600 A1 EP 1514600A1 EP 03405604 A EP03405604 A EP 03405604A EP 03405604 A EP03405604 A EP 03405604A EP 1514600 A1 EP1514600 A1 EP 1514600A1
Authority
EP
European Patent Office
Prior art keywords
pipette
calibration
volume
rotation
tube
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP03405604A
Other languages
English (en)
French (fr)
Other versions
EP1514600B1 (de
EP1514600B2 (de
Inventor
Jean-Pierre Uldry
Sylvain Christen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Socorex Isba SA
Original Assignee
Socorex Isba SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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Application filed by Socorex Isba SA filed Critical Socorex Isba SA
Priority to ES03405604T priority Critical patent/ES2289252T5/es
Priority to AT03405604T priority patent/ATE365075T1/de
Priority to EP03405604A priority patent/EP1514600B2/de
Priority to DE60314516T priority patent/DE60314516T3/de
Priority to US10/916,359 priority patent/US7204163B2/en
Publication of EP1514600A1 publication Critical patent/EP1514600A1/de
Publication of EP1514600B1 publication Critical patent/EP1514600B1/de
Publication of EP1514600B2 publication Critical patent/EP1514600B2/de
Application granted granted Critical
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/021—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
    • B01L3/0217—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids of the plunger pump type
    • B01L3/0224—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids of the plunger pump type having mechanical means to set stroke length, e.g. movable stops
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/14—Process control and prevention of errors
    • B01L2200/148—Specific details about calibrations
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/02—Identification, exchange or storage of information
    • B01L2300/025—Displaying results or values with integrated means
    • B01L2300/026—Drum counters

Definitions

  • the present invention relates to a piston pipette mechanical device comprising a pipette body, a piston-cylinder assembly, the cylinder being arranged so that it can be with replaceable tip and ejector endpiece, movable along the cylinder to eject a tip of the end of the cylinder, the said pipette body accommodating an ejection actuating device and a piston actuating device performing a stroke determined in longitudinal translation between a position of low stop and a high stop position to perform aspiration and dosing of liquids, with means of modification of the said race.
  • piston pipettes are known in the state of the art. We distinguish pipettes mechanical devices whose mechanism is entirely actuated by the hand of the user. When these pipettes have a way volume display, this one can be analog, digital and mechanical, or electronic. There are also many types of piston pipettes powered by an engine electrical equipment and whose display devices or adjustment or calibration devices are also performed by electromechanical or electronic means.
  • the present invention relates exclusively to pipettes to mechanical piston, with fixed or adjustable volume. When the volume is adjustable, the invention relates exclusively to pipettes whose volume display itself is mechanical.
  • volume-adjustable pipettes For highly repetitive laboratory operations for analysis, for example in test kits, it is preferred to use fixed volume pipettes.
  • volume-adjustable pipettes For small operations repetitive or in research laboratories, generally prefers to use volume-adjustable pipettes, allowing a wider range of use. Even if we do not takes into consideration that the range of volumes 1 ⁇ l to 1000 ⁇ l, which concerns the pipettes commonly called micro-pipettes, whereas pipettes called “macro-pipettes" cover the higher volume ranges, a full range of micro-pipettes usually represents more than 20 different objects present in a manufacturer's catalog. A great concern for manufacturers is therefore reducing the total number of parts different entering the constitution of the different micro-pipettes of the same series. He is particularly desirable to be able to use as many people as possible of common parts to make volume micro-pipettes fixed and variable volume, in the volume ranges comparable.
  • a pipette with adjustable volume comprising a pipette body, a piston-cylinder assembly, the cylinder being arranged so as to be provided with a replaceable tip, and a tip ejector device, movable along the cylinder to eject a mouthpiece the end of the cylinder, the so-called pipette body welcoming an ejection actuating device and a device piston actuator performing a determined stroke in longitudinal translation between a low stop position and a high stop position to perform the suction of liquids, with means for modifying said stroke, means for adjusting the pipetted volume, display means pipetting volume and calibration means, by the fact that said adjustment means, said display means and the said calibration means cooperate in a device for setting and calibration in which, during an operation of calibration, the said display means are adjusted so to match the displayed volume with the actual pipetted volume and that said adjustment and calibration device is housed inside the pipette body.
  • the adjustable volume pipette body shown in the figure 1 comprises an outer sleeve 14 which itself consists of a longitudinal portion 14a, substantially cylindrical but with a slight ergonomic bulge to fit the palm of the hand, with a substantially elliptical cross-section, of which the upper part is extended laterally by a stick 14b in a comma form intended to rest on the flank of the index of the user's hand.
  • the outer sleeve 14 accommodates an inner sleeve 13 which fits into the sleeve outside 14 on the same side as the butt 14b.
  • the sleeve interior 13 has an inner wall portion cylindrical with an arcuate section, which forms with the inner surface of the opposite zone of the outer sleeve 14 a cylindrical housing of circular section.
  • the sleeve interior 13 is thick enough to accommodate the tip ejection device, which includes a button ejector 10 surmounted by a protective cap 9.
  • the button ejector is extended by an ejector rod 18 on which are threaded an ejection spring 12 and a sleeve 11.
  • the inner sleeve 13 also houses a pinion tube 19 comprising a plurality of rotary gears, for example three pinions 19a, 19b, 19c, rotating about an axis parallel to the longitudinal axis of the pipette and cooperating with the setting and calibration device as it will be described later.
  • the top of the sleeve 13 is extended laterally by a ring 13a, coaxial with the housing cylindrical, which caps the upper opening of the sleeve 14.
  • a metering knob 3 protrudes from the top of the ring 13a.
  • the metering button 3 is intended to be embedded in the body of pipette by the user's thumb during operations pipetting, namely aspiration of liquid into the mouthpiece Disposable and ejection of this liquid.
  • the doser button 3 is pushed upwards by the pipetting spring 7, so that perform alternative translational movements according to the longitudinal axis of the pipette body.
  • the top of the button metering device 3 is plugged by a cap 1.
  • the cap 1 is easily removed by the user by means of a fingernail. he can be realized in different colors to facilitate visual identification of the pipette.
  • the metering knob 3 is threaded internally. He receives a adjusting screw 4 threaded externally, so that the rotation of the metering knob 3 causes the adjusting screw 4 longitudinal translation, when it is blocked itself in rotation as described below.
  • the adjusting screw 4 is shown in its extreme position lower.
  • the upper part of the adjusting screw 4 is recessed and receives a calibration key 2 which can slide in longitudinal translation in the recess of the screw of setting 4, but which is locked in rotation. To do this, the recess of the adjusting screw 4 and the calibration key can both be square.
  • the key to calibration is threaded into a ring 5.
  • the middle part of the adjusting screw 4 carries a bulge 4a, come from one piece with the body of the screw 4, on which rests an over-stroke spring 4b.
  • the other extremity of the overtravel spring 4b rests on an overtravel stop 4c fitted on and secured with the body of the screw setting 4.
  • the adjustment and calibration device is designated in its set by 8. It includes a calibration disk 8a.
  • the calibration disk 8a comprises an upper barrel 8b surrounding the body of the adjusting screw 4, which slides therein longitudinally, and a lower flange 8c in diameter greater than that of the barrel 8b.
  • the calibration disk 8a rests on the bottom 14c of the outer sleeve 14 and thus limits the stroke of the screw 4, when the lower face of the stop 4c gets in touch with him.
  • An 8d adjustment tube is based on 8h circular horizontal plate formed between flange 8c and the barrel 8b.
  • the adjustment tube 8d and the disc of calibration 8a are coupled by a dog clutch system coupling C, consisting of two toothed crowns being face, respectively formed on the 8h replat of the disk of calibration and on the lower end face of the tube 8d setting. Teeth are low in height and disengage easily.
  • the outer sleeve 14 houses, at the disc level 8a, a locking device consisting of a shoe 15 provided with an elastic clip 16. In position locked, this pad 15 prevents the rotation of the disk from calibration 8a.
  • the pad is manoeuvrable from the outside, by a hole of the sleeve 14, by any object having a fine point.
  • the calibration disk 8a is made integral in rotation the body of the adjusting screw 4 by means of ribs / grooves longitudinal conjugates.
  • the top of the 8d adjustment tube surrounds the bottom of the metering knob 3.
  • the 8d adjustment tube and the metering button 3 are also secured in rotation by ribs / conjugate grooves.
  • the adjustment tube has a lower part of outer diameter slightly decreased, forming a protrusion horizontal circular.
  • the 8d adjustment tube carries other share on this lower part a plurality of rings of counting, for example three rings 8e, 8f, 8g bearing on their periphery of the digits from 0 to 9, providing an indication digital volume of liquid pipetted.
  • the outer sleeve 14 has on its side opposite the butt 14b and at the height of the counting rings a window transparent 6 to read the volume indication.
  • the projection of the adjustment tube 8d facing the rings of counting comprises several teeth causing the pinion 19a.
  • the counting rings have a continuous toothing on the upper frontal face but only one indentation on the opposite end face, so that the rotation of the disc of setting 8d drives the first pinion, which in turn drives the first 8th disc which, for example after a lap complete, drives the second pinion 19b rotating a digit the second counting ring, and so on. This mechanism is in itself known.
  • the locking shoe 15 is in the locked position, preventing the rotation of the calibration disk 8a.
  • the disc calibration locks the rotation of the adjusting screw 4, which it itself is integral in rotation with the calibration key 2.
  • the user rotates the metering knob 3, which, by its internal thread, drives the adjusting screw 4.
  • This displacement in longitudinal translation operates on the stroke adjustment extending between the bottom of the stop of race 4c and the top of the calibration disc 8a.
  • This course determines itself the volume of liquid, since the screw of setting 4 is connected to the piston of the pipette by its end 4d in the form of a spherical head constituting a detachable connection.
  • the rotation of the metering knob 3 results in rotating the adjustment tube 8d and, via the gear tube 19, the 8th, 8f, 8g meter disks, as discussed above.
  • the claw system C is uncoupled, the tube 8d turns on the calibration disk 8a, the teeth of the segments teeth ripping one above the other.
  • the stroke defined by the distance between the overtravel stop 4c and the disc of 8a does not, in the majority of cases, correspond to displayed volume.
  • a calibration is necessary at the factory. The subsequent user may also wish periodically, for example for specific liquids or again after dismantling, cleaning and sterilization, recalibrate. An operation of calibration is carried out as follows:
  • the volume dispensed by the pipette can be 545 ⁇ l while the meter displays 210 ⁇ l.
  • the operation of calibration is to bring the value of the display to 545 ⁇ l corresponding to the actual volume, without changing the stroke.
  • the locking shoe 15 is unlocked, thus freeing the rotation of the disc from calibration 8a.
  • the cap 1 is removed to access the screw 2. This can be operated either by a coin or a screwdriver, either, after having partially slid outward, can be operated at the hand.
  • the rotation of the calibration key leads to turning the adjusting screw 4, which itself leads to rotation the calibration disc. While turning the key the user is careful not to touch the doser button 3 so as not to change the relative position button 3 / screw 4.
  • the calibration disc drives the tube of 8d setting in rotation, through the system of jaws C.
  • the rotation of the adjustment tube causes the rotation pinions of the pinion tube 19 and therefore the rotation of the counting rings.
  • the key is turned until the measured value, in this example 545 ⁇ l, is displayed.
  • the pad 15 is pushed back into the locking position to lock in angular position the calibration disc 8a and the adjusting screw 4.
  • the calibration key 2 is pushed back into its housing and the hood is replaced.
  • the value of the counter device being modeled on the stroke, the subsequent volume adjustments of the pipette are made simply by rotating the metering knob 3, which modifies this times the stroke by displacement in translation of the screw of adjustment 4 without moving in rotation thereof.
  • the fixed volume pipette body shown in Figure 2 comprises an outer sleeve 14 which itself consists of a longitudinal portion 14a, substantially cylindrical but with a slight ergonomic bulge to fit the palm of the hand, with a substantially elliptical cross-section, of which the upper part is extended laterally by a stick 14b in a comma form intended to rest on the flank of the index of the user's hand.
  • the outer sleeve 14 accommodates an inner sleeve 13 which fits into the sleeve outside 14 on the same side as the butt 14b.
  • the sleeve interior 13 has an inner wall portion cylindrical with an arcuate section, which forms with the inner surface of the opposite zone of the outer sleeve 14 a cylindrical housing of circular section.
  • the sleeve interior 13 is thick enough to accommodate the tip ejection device, which includes a button ejector 10 surmounted by a protective cap 9.
  • the button ejector is extended by an ejector rod 18 on which are threaded an ejection spring 12 and a sleeve 11.
  • the location of the pinion tube 19 described above remains empty.
  • the top of the sleeve 13 extends laterally by a ring 13a, coaxial with the cylindrical housing, which cap the upper opening of the sleeve 14.
  • a metering knob 3 protrudes from the top of the ring 13a.
  • the metering button 3 is intended to be embedded in the body of pipette by the user's thumb during operations pipetting, namely aspiration of liquid into the mouthpiece Disposable and ejection of this liquid.
  • the doser button 3 is pushed upwards by the pipetting spring 7, so that perform alternative translational movements according to the longitudinal axis of the pipette body.
  • the top of the button metering device 3 is plugged by a cap 1.
  • the cap 1 is easily removed by the user by means of a fingernail. he can be realized in different colors to facilitate visual identification of the pipette.
  • the metering knob 3 is threaded internally. He receives a adjusting screw 4 externally threaded.
  • the adjusting screw 4 is shown in its extreme position lower.
  • the upper part of the adjusting screw 4 is recessed and receives a calibration key 2 which can slide in longitudinal translation in the recess of the screw of setting 4, but which is locked in rotation. To do this, the recess of the adjusting screw 4 and the calibration key can both be square.
  • the key to calibration is threaded into a ring 5.
  • the middle part of the adjusting screw 4 carries a bulge 4a, come from one piece with the body of the screw 4, on which rests an over-stroke spring 4b.
  • the other extremity of the overtravel spring 4b rests on an overtravel stop 4c fitted on and secured with the body of the screw setting 4.
  • the calibration device is designated as a whole by 8 '. It includes a calibration disk 8a.
  • the record of calibration 8a comprises an upper barrel 8b surrounding the body of the adjusting screw 4, which slides there longitudinally, and a lower flange 8c in diameter greater than that of the barrel 8b.
  • the calibration disk 8a rests on the bottom 14c of the outer sleeve 14 and thus limits the stroke of the screw 4, when the lower face of the stop 4c gets in touch with him.
  • the calibration disk 8a can be identical to that shown in Figure 1, and bear a Circular toothed crown, formed on the plate 8h of the disc calibration; but, in the case of a fixed volume pipette, this crown has no function.
  • the outer sleeve 14 at the level of the calibration disk 8a a device for lock consisting of a shoe 15 provided with a clip 16. In the locked position, this pad 15 prevents the rotation of the calibration disk 8a.
  • the pad is manoeuvrable from the outside, through a hole in the sleeve 14, by any object having a fine point.
  • the calibration disk 8a is secured in rotation of the body of the adjusting screw 4 to means of ribs / longitudinal grooves conjugate.
  • the tube 8d has like the tube 8d described above a lower part of outer diameter slightly decreased, forming a horizontal circular projection. But the tube 8d 'does wears no counting rings.
  • the outer sleeve 14 has on its side opposite the 14b stock and at the height of the lower part of the tube 8d a opaque plate 6 'replacing window 6.
  • the stroke defined by the distance between the overtravel stop 4c and the disc of 8a does not, in the majority of cases, correspond to nominal volume.
  • a calibration is necessary at the factory. The subsequent user may also wish periodically, for example after disassembly operations, cleaning and sterilization, recalibrate.
  • a calibration operation is performed as follows:
  • the volume dispensed by the pipette can be 545 ⁇ l while the nominal value is 500 ⁇ l.
  • the operation calibration is to bring the value of the actual volume to the nominal value.
  • the locking shoe 15 is unlocked, thus freeing the rotation of the disc from calibration 8a.
  • the cap 1 is removed to access the screw 2.
  • This can be operated either by a screwdriver or a coin, that is, after having partially slid outward, can be operated at the hand.
  • the rotation of the calibration key leads to turning the adjusting screw 4, which itself leads to rotation the calibration disc.
  • the calibration disc slides under the tube 8d '.
  • the adjusting screw moves in longitudinal translation, modifying the stroke, and so the volume pipetted. After measuring this volume, the operation can be repeated until the measured value coincides with the nominal value or with another desired value by the user.
  • the pad 15 is pushed back into position lock in order to lock in the angular position the calibration disk 8a and the adjusting screw 4.
  • the key of calibration 2 is pushed back into its housing and the cap is replaced.
  • variable volume pipette and fixed volume pipette body use, in the same volume range, a large majority common rooms. These are identified by numbers identical reference numbers in figures 1 and 2.
  • the man of the profession will observe in particular that the same piece, the ring of calibration 8a, provides several functions, namely stop end of stroke, adjustment and / or calibration in the two types of pipette.
  • One essential piece, namely the tube 8d, respectively 8d ' has structures and different functions: the tube 8d serves both as a guide for metering button 3, housing spring 7 and provides a adjustment function as explained above.
  • the tube 8d which differs essentially from the tube 8d by the presence of ribs the outer blocking it in rotation, serves only as a guide and of housing. It will be noted that the tubes 8d and 8d 'have moreover identical dimensions.
  • the pipette body to adjustable volume also has a set of rings counting and drive gears described above, that are not present in the body of the volume pipette fixed.
  • the entire adjustment and calibration device is housed in the longitudinal pipette body, without increase volume of it, and the display, which is not hidden by the thumb, remains visible from the operator holding his pipette in a natural way.
  • the arrangement of counting disks and sprockets of training allows in particular, without increasing the body volume of the pipette, to arrange the eject button 10 above the butt of the outer sleeve, which is ergonomically favorable, the thumb of the user exercising more easily press the eject button when it comes on top of the slice of the hand that when it deviates from it, which would be the case if the button ejection had been placed on the opposite side.

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  • Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Devices For Use In Laboratory Experiments (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Steroid Compounds (AREA)
EP03405604A 2003-08-19 2003-08-19 Mechanische Kolbenpipette Expired - Lifetime EP1514600B2 (de)

Priority Applications (5)

Application Number Priority Date Filing Date Title
ES03405604T ES2289252T5 (es) 2003-08-19 2003-08-19 Pipeta de pistón mecánica
AT03405604T ATE365075T1 (de) 2003-08-19 2003-08-19 Mechanische kolbenpipette
EP03405604A EP1514600B2 (de) 2003-08-19 2003-08-19 Mechanische Kolbenpipette
DE60314516T DE60314516T3 (de) 2003-08-19 2003-08-19 Mechanische Kolbenpipette
US10/916,359 US7204163B2 (en) 2003-08-19 2004-08-11 Mechanical piston pipette

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP03405604A EP1514600B2 (de) 2003-08-19 2003-08-19 Mechanische Kolbenpipette

Publications (3)

Publication Number Publication Date
EP1514600A1 true EP1514600A1 (de) 2005-03-16
EP1514600B1 EP1514600B1 (de) 2007-06-20
EP1514600B2 EP1514600B2 (de) 2012-02-22

Family

ID=34130400

Family Applications (1)

Application Number Title Priority Date Filing Date
EP03405604A Expired - Lifetime EP1514600B2 (de) 2003-08-19 2003-08-19 Mechanische Kolbenpipette

Country Status (5)

Country Link
US (1) US7204163B2 (de)
EP (1) EP1514600B2 (de)
AT (1) ATE365075T1 (de)
DE (1) DE60314516T3 (de)
ES (1) ES2289252T5 (de)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2165765A1 (de) * 2008-09-12 2010-03-24 Eppendorf Ag Pipettiervorrichtung mit Doppelgewinde
FR3080050A1 (fr) * 2018-04-17 2019-10-18 Gilson Sas Dispositif de verrouillage d'une vis de reglage de volume pour un systeme de pipetage
DE102020002780B3 (de) 2020-05-11 2021-10-14 Brand Gmbh + Co Kg Pipette und Verfahren zum Betreiben einer Pipette
DE102021112246A1 (de) 2020-05-11 2021-11-11 Brand Gmbh + Co Kg Pipette und Verfahren zum Betreiben einer Pipette

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6923938B2 (en) * 2001-10-16 2005-08-02 Matrix Technologies Corporation Hand-held pipettor
DE102005033378B4 (de) * 2005-07-16 2012-05-31 Eppendorf Ag Kolbenhubpipette
PL211690B1 (pl) * 2007-11-23 2012-06-29 Pz Htl Społka Akcyjna Pipeta z nastawianą objętością pobieranej cieczy
WO2009114350A1 (en) * 2008-03-07 2009-09-17 Cook Vascular Incorporated Pipette aspiration device
PL220934B1 (pl) * 2009-08-28 2016-01-29 PZ HTL Spółka Akcyjna Pipeta mechaniczna z nastawianą wartością objętości pobieranej cieczy
FI20106184A0 (fi) 2010-11-11 2010-11-11 Thermo Fisher Scientific Oy Kahvapipetti
US9295986B2 (en) * 2012-05-02 2016-03-29 Eppendorf Ag Pipette with releasable locking of rotational position of actuating element
US10016755B2 (en) 2015-01-08 2018-07-10 Integra Biosciences Ag Manual pipette with selectable plunger force
CN107530702B (zh) * 2015-04-16 2019-06-11 因特格拉生物科学股份公司 用于手动移液器的容量调节
FR3040896B1 (fr) * 2015-09-15 2017-10-13 Gilson Sas Pipette de prelevement comprenant un organe de commande a double fonction d'ejection de cone et de deverrouillage du systeme de reglage de volume
FR3049877B1 (fr) * 2016-04-12 2018-04-13 Gilson Sas Pipette pour le prelevement d'une plage etendue de volumes de liquide
DE102016121814A1 (de) * 2016-11-14 2018-05-17 Ika-Werke Gmbh & Co. Kg Handdosiervorrichtung
EP3684514B1 (de) * 2017-09-19 2024-10-30 Mettler-Toledo Rainin, LLC Mechanismus zur schnellen anpassung der pipettenvolumeneinstellung
DE102022104546A1 (de) * 2022-02-25 2023-08-31 Eppendorf Se Pipette mit verstellbarem Pipettiervolumen und Verriegelungssystem

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US4165646A (en) 1978-07-26 1979-08-28 Shapiro Justin J Adjustable micro-dispensing liquid pipet
EP0153058A2 (de) * 1984-02-14 1985-08-28 Labsystems Oy Pipette mit einstellbarem Inhalt
EP0649678A1 (de) 1993-10-21 1995-04-26 Eppendorf-Netheler-Hinz Gmbh Kolbenhubpipette
US5413006A (en) * 1992-09-28 1995-05-09 Gilson Medical Electronics (France) S.A. Pipette for sampling and dispensing adjustable volumes of liquids
US5650124A (en) * 1995-07-24 1997-07-22 Gilson; Warren E. Adjustable pipette
US5792424A (en) * 1996-03-05 1998-08-11 Rainin Instrument Co., Inc. Manual pipette with delayed-action home position latch
US6295880B1 (en) * 1999-12-08 2001-10-02 Warren E. Gilson Adjustable pipette
FR2807343A1 (fr) * 2000-04-07 2001-10-12 Gilson Sa Pipette de prelevement munie de moyens de reglage du volume a prelever
EP1197264A2 (de) * 2000-10-11 2002-04-17 Thermo Labsystems Oy Pipette à volume réglable

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Publication number Priority date Publication date Assignee Title
US5998218A (en) * 1996-09-09 1999-12-07 Sherwood Services Ag Calibration system for an electronically monitored mechanical pipette

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4165646A (en) 1978-07-26 1979-08-28 Shapiro Justin J Adjustable micro-dispensing liquid pipet
EP0153058A2 (de) * 1984-02-14 1985-08-28 Labsystems Oy Pipette mit einstellbarem Inhalt
US5413006A (en) * 1992-09-28 1995-05-09 Gilson Medical Electronics (France) S.A. Pipette for sampling and dispensing adjustable volumes of liquids
EP0649678A1 (de) 1993-10-21 1995-04-26 Eppendorf-Netheler-Hinz Gmbh Kolbenhubpipette
US5531131A (en) * 1993-10-21 1996-07-02 Eppendorf-Netheler-Hinz Gmbh Device for adjusting correction factor of a plunger lift pipet
US5650124A (en) * 1995-07-24 1997-07-22 Gilson; Warren E. Adjustable pipette
US5792424A (en) * 1996-03-05 1998-08-11 Rainin Instrument Co., Inc. Manual pipette with delayed-action home position latch
US6295880B1 (en) * 1999-12-08 2001-10-02 Warren E. Gilson Adjustable pipette
FR2807343A1 (fr) * 2000-04-07 2001-10-12 Gilson Sa Pipette de prelevement munie de moyens de reglage du volume a prelever
EP1197264A2 (de) * 2000-10-11 2002-04-17 Thermo Labsystems Oy Pipette à volume réglable

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2165765A1 (de) * 2008-09-12 2010-03-24 Eppendorf Ag Pipettiervorrichtung mit Doppelgewinde
FR3080050A1 (fr) * 2018-04-17 2019-10-18 Gilson Sas Dispositif de verrouillage d'une vis de reglage de volume pour un systeme de pipetage
WO2019202246A1 (fr) * 2018-04-17 2019-10-24 Gilson Sas Dispositif de verrouillage d'une vis de reglage de volume pour un systeme de pipetage
CN111989160A (zh) * 2018-04-17 2020-11-24 吉尔松有限合伙公司 用于锁定移液系统的容量调节螺钉的装置
CN111989160B (zh) * 2018-04-17 2022-02-11 吉尔松有限合伙公司 用于锁定移液系统的容量调节螺钉的装置
US11559800B2 (en) 2018-04-17 2023-01-24 Gilson Sas Device for locking a volume adjustment screw for a pipetting system
DE102020002780B3 (de) 2020-05-11 2021-10-14 Brand Gmbh + Co Kg Pipette und Verfahren zum Betreiben einer Pipette
DE102021112246A1 (de) 2020-05-11 2021-11-11 Brand Gmbh + Co Kg Pipette und Verfahren zum Betreiben einer Pipette

Also Published As

Publication number Publication date
DE60314516T3 (de) 2012-07-19
US7204163B2 (en) 2007-04-17
EP1514600B1 (de) 2007-06-20
EP1514600B2 (de) 2012-02-22
ES2289252T3 (es) 2008-02-01
ES2289252T5 (es) 2012-06-12
DE60314516T2 (de) 2008-02-28
ATE365075T1 (de) 2007-07-15
DE60314516D1 (de) 2007-08-02
US20050039550A1 (en) 2005-02-24

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