EP1377180B1 - Mikrokapseln - Google Patents

Mikrokapseln Download PDF

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Publication number
EP1377180B1
EP1377180B1 EP02761877A EP02761877A EP1377180B1 EP 1377180 B1 EP1377180 B1 EP 1377180B1 EP 02761877 A EP02761877 A EP 02761877A EP 02761877 A EP02761877 A EP 02761877A EP 1377180 B1 EP1377180 B1 EP 1377180B1
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EP
European Patent Office
Prior art keywords
pectin
matrix material
pectic substance
treating
obtainable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
EP02761877A
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English (en)
French (fr)
Other versions
EP1377180A1 (de
Inventor
Anders Vagn Pedersen
Morten Mohr Hansen
Susanne Lund Madsen
Nina Musaeus Jensen
Carsten Lynggaard Hansen
Annette Kristensen Strarup
Karin Meyer Hansen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BASF SE
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BASF SE
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Publication date
Application filed by BASF SE filed Critical BASF SE
Publication of EP1377180A1 publication Critical patent/EP1377180A1/de
Application granted granted Critical
Publication of EP1377180B1 publication Critical patent/EP1377180B1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y301/00—Hydrolases acting on ester bonds (3.1)
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/70—Fixation, conservation, or encapsulation of flavouring agents
    • A23L27/72—Encapsulation
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/20—Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents
    • A23L29/206—Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents of vegetable origin
    • A23L29/231—Pectin; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/15—Vitamins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
    • A23P10/00—Shaping or working of foodstuffs characterised by the products
    • A23P10/30—Encapsulation of particles, e.g. foodstuff additives
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Nutrition Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Mycology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicinal Preparation (AREA)
  • General Preparation And Processing Of Foods (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Cosmetics (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Fodder In General (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Jellies, Jams, And Syrups (AREA)

Claims (15)

  1. Mikrokapseln, umfassend eine Wirksubstanz, eingebettet in ein Matrixmaterial, dadurch gekennzeichnet, dass das Matrixmaterial durch Behandeln einer Pektinsubstanz mit ein oder mehreren Enzymen, ausgewählt aus der Gruppe, bestehend aus Esterasen (E.C.3.1.), Glucosidasen (E.C.3.2.), Peptidasen (E.C.3.4.), Proteasen (E.C.3.4.) und Lyasen (E.C.4.), erhaltbar ist.
  2. Mikrokapseln nach Anspruch 1, worin das Matrixmaterial durch Behandeln einer Pektinsubstanz mit ein oder mehreren Enzymen, die zum Modifizieren der neutralzuckerreichen Zonen (hairy regions) fähig sind, erhaltbar ist.
  3. Mikrokapseln nach Anspruch 1 oder 2, worin das Matrixmaterial durch Behandeln einer Pektinsubstanz mit ein oder mehreren Enzymen erhaltbar ist, die zum Modifizieren des Rückgrats der homogenen Polygalacturonsäure-Abschnitte (smooth regions) fähig sind, um dabei separate Elemente, umfassend hairy regions, zu bilden.
  4. Mikrokapseln nach Anspruch 1, worin das Matrixmaterial durch Behandeln einer Pektinsubstanz mit Papain, Pepsin oder Trypsin erhaltbar ist.
  5. Mikrokapseln nach Anspruch 4, worin das Matrixmaterial durch Behandeln der Pektinsubstanz mit Papain, wie etwa Collupulin©, erhaltbar ist.
  6. Mikrokapseln nach Anspruch 1, worin das Matrixmaterial durch Behandeln der Pektinsubstanz mit einer Exopeptidase, wie etwa Carboxypeptidase, erhaltbar ist.
  7. Mikrokapseln nach Anspruch 1-3, worin das Matrixmaterial durch Behandeln einer Pektinsubstanz mit einem deacetylierenden Enzym erhaltbar ist.
  8. Mikrokapseln nach Anspruch 1-3, worin das Matrixmaterial durch Behandeln einer Pektinsubstanz mit einem entzweigenden Enzym erhaltbar ist.
  9. Mikrokapseln nach Anspruch 1-3, worin das Matrixmaterial durch Behandeln einer Pektinsubstanz mit einem Gemisch aus α-Arabinofuranosidase, Galactanase und Arabinanase erhaltbar ist.
  10. Mikrokapseln nach Anspruch 1-3, worin das Matrixmaterial durch Behandeln der Pektinsubstanz mit einer Lyase, wie etwa Pectinase PL-Lyase, erhaltbar ist.
  11. Mikrokapseln nach einem der Ansprüche 1-10, worin die Pektinsubstanz von einem Gemüse stammt.
  12. Mikrökapseln nach einem der Ansprüche 1-10, worin die Pektinsubstanz von Orange, Traube, Zuckerrübe, Sojabohne, Leinsamen, Jerusalem-Artischocke, Selerie, Kartoffeln und Rote Bete stammt.
  13. Verfahren zum Herstellen von Mikrokapseln, die eine Wirksubstanz, eingebettet in ein Matrixmaterial, enthalten, umfassend die Schritte des Bereitstellens eines wässrigen Mediums von einer Pektinsubstanz, modifiziert durch Behandeln mit ein oder mehreren Enzymen, ausgewählt aus der Gruppe, bestehend aus Esterasen (E.C.3.1.), Glucosidasen (E.C.3.2.), Peptidasen (E.C.3.4.), Proteasen (E.C.3.4.) und Lyasen (E.C.4.); Zugeben zu der Lösung wenigstens einer Wirksubstanz, Feinzerteilen und Trocknen des derart erhaltenen Gemischs, um eine Masse von Partikeln zu erhalten, die jeweils eine Vielzahl von flüssigen oder festen Mikropartikeln der Wirksubstanz, eingebettet in eine Matrix, umfassend die Modifizierte Pektinsubstanz, enthalten.
  14. Produkt, umfassend Mikrokapseln nach einem der Ansprüche 1-12.
  15. Produkt nach Anspruch 14, dadurch gekennzeichnet, dass es ein Nahrungsmittel, eine Nahrungsmittelergänzung, ein Getränk, ein pharmazeutisches oder veterinärpharmazeutisches Produkt, ein Futtermittel oder eine Futtermittelergänzung, ein persönliches Pflegeprodukt oder ein Haushaltsprodukt ist.
EP02761877A 2001-04-10 2002-04-10 Mikrokapseln Expired - Lifetime EP1377180B1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DK200100594 2001-04-10
DKPA200100594 2001-04-10
PCT/DK2002/000238 WO2002082924A1 (en) 2001-04-10 2002-04-10 Microcapsules

Publications (2)

Publication Number Publication Date
EP1377180A1 EP1377180A1 (de) 2004-01-07
EP1377180B1 true EP1377180B1 (de) 2007-08-29

Family

ID=8160431

Family Applications (1)

Application Number Title Priority Date Filing Date
EP02761877A Expired - Lifetime EP1377180B1 (de) 2001-04-10 2002-04-10 Mikrokapseln

Country Status (10)

Country Link
US (1) US20040170693A1 (de)
EP (1) EP1377180B1 (de)
JP (1) JP2004529760A (de)
CN (1) CN1236692C (de)
AT (1) ATE371376T1 (de)
DE (1) DE60222106T2 (de)
DK (1) DK1377180T3 (de)
ES (1) ES2288558T3 (de)
NO (1) NO324980B1 (de)
WO (1) WO2002082924A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006516396A (ja) * 2003-01-31 2006-07-06 デーエスエム アイピー アセッツ ベー． ヴェー． カロテノイドを含む新規な組成物
JP4918859B2 (ja) * 2004-08-11 2012-04-18 味の素株式会社 カプシノイド含有マイクロカプセルの製造法
JP2006050946A (ja) * 2004-08-11 2006-02-23 Ajinomoto Co Inc ペクチンを壁材とするマイクロカプセル
SI22342A (sl) * 2007-10-04 2008-02-29 Vitiva Proizvodnja In Storitve D.D. Antioksidativna in antimikrobioloska zascita mascob in mascobo-vsebujocih živil z mesanico ekstrakta ustnatic in zelenega caja
EP2213715A1 (de) 2009-02-02 2010-08-04 The Procter & Gamble Company Flüssige Handspülmittelzusammensetzung
CN103221070B (zh) 2010-08-30 2019-07-12 哈佛大学校长及研究员协会 用于狭窄病变和溶解血栓疗法的切变控制释放
US20130251855A1 (en) * 2012-03-21 2013-09-26 Pepsico, Inc. Aqueous product comprising oil-containing microcapsules and method for the manufacture thereof
CN107594597B (zh) * 2017-07-31 2020-05-12 浙江新和成股份有限公司 一种脂溶性营养素微胶囊及其制备方法
CN110742278B (zh) * 2019-10-26 2022-09-13 大连医诺生物股份有限公司 植物蛋白体系油脂微囊粉及其制备方法
CN110801021A (zh) * 2019-11-15 2020-02-18 江苏独角兽生物科技有限公司 一种利用改性果胶包埋肠道复合益生菌的方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4977252A (en) * 1988-03-11 1990-12-11 National Starch And Chemical Investment Holding Corporation Modified starch emulsifier characterized by shelf stability
DK42092D0 (de) * 1992-03-27 1992-03-27 Novo Nordisk As
EP0580252A2 (de) * 1992-07-20 1994-01-26 Quest International B.V. Verbesserungen bezüglich Pektin-Methylesterase
IL107791A (en) * 1992-11-30 1997-04-15 Gist Brocades Nv Use of pectinesterase in the treatment of fruit and vegetables
DK81193D0 (da) * 1993-07-06 1993-07-06 Novo Nordisk As Enzym
CN1089345C (zh) * 1996-01-26 2002-08-21 诺沃奇梅兹有限公司 含果胶的材料的酶促凝胶化及其所得产品和用途
ATE221325T1 (de) * 1996-12-11 2002-08-15 Dsm Nv Trübe fruchtsäfte und verfahren zu ihrer herstellung
US5929051A (en) * 1998-05-13 1999-07-27 Carrington Laboratories, Inc. Aloe pectins
GB9820817D0 (en) * 1998-09-24 1998-11-18 Danisco Enzyme
AU3915000A (en) * 1999-03-31 2000-10-16 Hercules Incorporated Pectin having reduced calcium sensitivity
WO2000070967A1 (en) * 1999-05-21 2000-11-30 Chr. Hansen A/S A colouring substance composition and a method of manufacturing same

Also Published As

Publication number Publication date
DK1377180T3 (da) 2007-12-27
JP2004529760A (ja) 2004-09-30
US20040170693A1 (en) 2004-09-02
NO324980B1 (no) 2008-01-14
DE60222106T2 (de) 2007-12-27
ATE371376T1 (de) 2007-09-15
EP1377180A1 (de) 2004-01-07
NO20034547L (no) 2003-12-10
CN1501776A (zh) 2004-06-02
CN1236692C (zh) 2006-01-18
WO2002082924A1 (en) 2002-10-24
DE60222106D1 (de) 2007-10-11
ES2288558T3 (es) 2008-01-16
NO20034547D0 (no) 2003-10-09

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