EP1302410B1 - System for transporting goods at constant temperature - Google Patents

System for transporting goods at constant temperature Download PDF

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Publication number
EP1302410B1
EP1302410B1 EP01124070A EP01124070A EP1302410B1 EP 1302410 B1 EP1302410 B1 EP 1302410B1 EP 01124070 A EP01124070 A EP 01124070A EP 01124070 A EP01124070 A EP 01124070A EP 1302410 B1 EP1302410 B1 EP 1302410B1
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EP
European Patent Office
Prior art keywords
container
double
walled
cells
likewise
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
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EP01124070A
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German (de)
French (fr)
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EP1302410A1 (en
Inventor
Dipl.-Ing. Kai Bienert
Dipl.-Ing. Dirk Nehring
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Delta T Gesellschaft fur Medizintechnik GmbH
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Delta T Gesellschaft fur Medizintechnik GmbH
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Publication date
Application filed by Delta T Gesellschaft fur Medizintechnik GmbH filed Critical Delta T Gesellschaft fur Medizintechnik GmbH
Priority to DE50114568T priority Critical patent/DE50114568D1/en
Priority to AT01124070T priority patent/ATE417002T1/en
Priority to ES01124070T priority patent/ES2320409T3/en
Priority to EP01124070A priority patent/EP1302410B1/en
Priority to DK01124070T priority patent/DK1302410T3/en
Priority to US10/022,406 priority patent/US20030072687A1/en
Publication of EP1302410A1 publication Critical patent/EP1302410A1/en
Application granted granted Critical
Publication of EP1302410B1 publication Critical patent/EP1302410B1/en
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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D81/00—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
    • B65D81/38—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents with thermal insulation
    • B65D81/3813—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents with thermal insulation rigid container being in the form of a box, tray or like container
    • B65D81/382—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents with thermal insulation rigid container being in the form of a box, tray or like container provided with liquid material between double walls
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/16—Holders for containers
    • A61J1/165—Cooled holders, e.g. for medications, insulin, blood, plasma
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
    • F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
    • F25D3/00—Devices using other cold materials; Devices using cold-storage bodies
    • F25D3/02—Devices using other cold materials; Devices using cold-storage bodies using ice, e.g. ice-boxes
    • F25D3/06—Movable containers
    • F25D3/08—Movable containers portable, i.e. adapted to be carried personally
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
    • F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
    • F25D2303/00—Details of devices using other cold materials; Details of devices using cold-storage bodies
    • F25D2303/08—Devices using cold storage material, i.e. ice or other freezable liquid
    • F25D2303/082—Devices using cold storage material, i.e. ice or other freezable liquid disposed in a cold storage element not forming part of a container for products to be cooled, e.g. ice pack or gel accumulator
    • F25D2303/0822—Details of the element
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
    • F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
    • F25D2303/00—Details of devices using other cold materials; Details of devices using cold-storage bodies
    • F25D2303/08—Devices using cold storage material, i.e. ice or other freezable liquid
    • F25D2303/083—Devices using cold storage material, i.e. ice or other freezable liquid using cold storage material disposed in closed wall forming part of a container for products to be cooled
    • F25D2303/0831—Devices using cold storage material, i.e. ice or other freezable liquid using cold storage material disposed in closed wall forming part of a container for products to be cooled the liquid is disposed in the space between the walls of the container
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
    • F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
    • F25D2331/00—Details or arrangements of other cooling or freezing apparatus not provided for in other groups of this subclass
    • F25D2331/80—Type of cooled receptacles
    • F25D2331/804—Boxes
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F28—HEAT EXCHANGE IN GENERAL
    • F28D—HEAT-EXCHANGE APPARATUS, NOT PROVIDED FOR IN ANOTHER SUBCLASS, IN WHICH THE HEAT-EXCHANGE MEDIA DO NOT COME INTO DIRECT CONTACT
    • F28D20/00—Heat storage plants or apparatus in general; Regenerative heat-exchange apparatus not covered by groups F28D17/00 or F28D19/00
    • F28D20/02—Heat storage plants or apparatus in general; Regenerative heat-exchange apparatus not covered by groups F28D17/00 or F28D19/00 using latent heat

Definitions

  • the invention relates to a system for transporting goods at constant temperatures with a storage, transport and protective container for perishable products and in particular storage, transport and protective container for blood and medical devices having the features of the preamble of claim 1.
  • the EP-A 1 006 058 discloses a container for transporting goods at constant temperature intervals, wherein the container comprising the goods, is formed of two complementary double-walled cells and in the double wall, a temperature control medium is filled, which in the Constant temperature intervals has a phase transition.
  • the US Pat. No. 4,470,264 discloses a container for transporting blood products at constant temperature intervals, the container comprising the goods being formed of two complementary, respectively double-walled cells.
  • the container In the container are pockets that are filled with tempering, which has a phase transition at the same temperature intervals. At least part of the container may be transparent to reveal the inner pockets.
  • the object of the invention is to provide a system for transporting goods at constant temperatures, in particular for the temperature-controlled transport of blood and medical products, which protects completely or mechanically several or more blood products and keeps them in a prescribed temperature interval. Another object of the invention is also to make visible on the container, whether temperature intervals were met.
  • a system for transporting goods at constant temperatures in particular for the transport of blood and medical products, a storage, protection and transport container for perishable products with a double wall filled from the inside with a liquid or solid latent heat storage is, and at the same time has an insulating effect.
  • the transport container is designed so that it is possible to connect two identical cells via preferably several snaps on the long sides. The result is a mechanically protected by external impact cavity between the two containers, which is intended for the storage of blood products.
  • the container of two complementary, each double-walled cells and a likewise complementary, double-walled ring is formed, which can be connected to longitudinal sides via snaps.
  • the complementary, double-walled ring with snaps allows the interior to be enveloped to be enlarged.
  • the two complementary, double-walled cells serve as the bottom and lid.
  • the double-walled ring is also filled with a liquid that acts as a temperature storage and can deliver or absorb large amounts of energy during their phase change.
  • the container is thus particularly well suited for the storage and transport of red blood cell concentrates and other blood products, antibodies, cells, or biotechnologically produced pharmaceutical products that must be transported between 2 to 6 ° C, suitable.
  • n-hydrocarbon chains are used to stabilize temperature ranges above 0 ° C, namely n-paraffins that satisfy the molecular formula C n H 2n + 2 .
  • the container is filled with an aqueous salt solution or an ethanol-water mixture as tempering, which has a phase transition between liquid and solid between - 20 ° C and - 40 ° C.
  • the container is thus particularly well suited for the storage and transport of platelets and other blood products that must be transported between 20 and 24 ° C, suitable.
  • the material of the double wall is transparent, in particular transparent plastic, so that the state of aggregation of the latent heat storage material is visible.
  • the container is therefore particularly well suited for the control of the temperature profile and thus the cold chain.
  • the double wall of diffusion-tight plastics such as polyamide, z.
  • Kevlar or made of metals such as aluminum, steel or cast iron.
  • the transport container is stackable, since it has on the back arresting fasteners.
  • At least two elements connected to the snap to the transport container are each sealable or sealable.
  • the container has at least one eyelet to seal, so that can prevent or detect unauthorized opening.
  • the elements of the storage, protection and transport container are provided with tongue and groove, so that the heat transfer is minimized.
  • the elements of the storage, protection and transport container are connected to a hinge.
  • the elements of the storage, protection and transport container are provided with a carrying handle.
  • the container is internally equipped with a thermometer, in particular an adhesive tape thermometer or a liquid crystal thermometer and / or electronically readable temperature recording device.
  • the system for transporting goods at constant temperatures comprises a cell-forming element 1 of a storage, protection and transport container, which is connected to a second, same element 10 (also forming a cell).
  • Fig. 2 can be connected via snaps 2.
  • the element 1 forms with its inner side and the attached second same element 10 so a cavity 3, which is shielded by a respective double wall of the elements 1 and 10 and by groove 4 and spring 5 at joint edges 6 from the outside environment.
  • the cavity 3 serves to accommodate blood products (not shown) or other products, such as antibodies, cells, or biotechnologically produced pharmaceutical products, which are in their original packaging.
  • Fig. 2 The elements 1 and 10 each contain a liquid or solid latent heat storage within the double wall.
  • the elements have on the outside recesses 8 and projections 7, so that a lock and thus a stackability is guaranteed. With the help of an outer strip (not shown), two elements can be sealed together.
  • a ring-forming element 20 for enlarging the cavity 3 of the storage, protection and transport container is equipped according to the double-walled elements 1 and 10 and complementary to the elements 1 and 10 with which it passes through groove 4 and tongue 5 at joint edges 6 can be connected.
  • Fig. 4 Corresponding features are indicated by the reference numerals Fig. 1 . 2 and 3 designated.
  • the system for transporting goods at constant temperatures is designed as an enlarged storage, protection and transport container with the cell-forming element 1, which also forms a cell, second same element 10 and the one ring forming, to the elements. 1 and 10 each complementary element 20, which are each connected via snaps 2 with the element 20.
  • the double wall of the elements 1, 10 and 20 is made of an insulating, transparent plastic material or of diffusion-tight plastics, such as polyamide, z. As Kevlar, or made of metals such as aluminum, steel or cast iron.
  • Elements 1, 10 and 20 are each with closable openings (not shown) for filling or emptying the cells forming the elements 1, 10 and 20 with a latent heat storage having a melting point between 20 ° C to 24 ° C, 2 ° C to 6 ° C and -20 ° C to -30 ° C, up to 24 ° C, 2 ° C to 6 ° C and -20 ° C to -40 ° C, in particular with paraffin, on substrates immobilized paraffin or a butanediol-water mixture, an aqueous salt solution or an ethanol-water mixture provided.
  • n-hydrocarbon chains can be used, namely n-paraffins which satisfy the molecular formula C n H 2n + 2 .
  • Transparent walls of the storage, protection and transport container can be seen on the frozen state of the latent heat storage that the appropriate temperature level has been maintained.
  • blood products such as red cell concentrates and platelets can be easily transported and handled at temperatures of 2 to 6 ° C and 20 to 24 ° C.
  • thermometer (not shown), in particular an adhesive tape thermometer, a liquid crystal thermometer and / or electronically readable temperature recording device, for the selected From 20 ° C to 24 ° C, 2 ° C to 6 ° C and -20 ° C to -30 ° C, within which the temperatures should remain the same.
  • the container of two or three complementary, each double-walled cells is provided with at least one eyelet (not shown), which allows sealing two complementary cells by means of a seal, so that can prevent or detect unauthorized opening.

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  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Mechanical Engineering (AREA)
  • Combustion & Propulsion (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Thermal Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Packages (AREA)
  • Air Transport Of Granular Materials (AREA)
  • Polymerisation Methods In General (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

A box for transporting blood products, antibodies, cells or pharmaceutical products produced by biotechnology at a constant temperature is double-walled. The cavity between the walls is filled with a substance which changes phase with changes in temperature.

Description

Die Erfindung betrifft ein System zum Transport von Gütern bei gleichbleibenden Temperaturen mit einem Aufbewahr-, Transport- und Schutzbehälter für leicht verderbliche Produkte und insbesondere Aufbewahr-, Transport- und Schutzbehälter für Blut- und Medizinprodukte mit den Merkmalen des Oberbegriffs des Anspruchs 1.The invention relates to a system for transporting goods at constant temperatures with a storage, transport and protective container for perishable products and in particular storage, transport and protective container for blood and medical devices having the features of the preamble of claim 1.

Beim Transport und der Lagerung von Blutprodukten ist es erforderlich eine dauerhafte Kühlkette bei Temperaturen von 2 bis 6 °C, < - 20 °C und 20 bis 24 °C einzuhalten, um eine lebensnotwendige hohe Qualität der Produkte zu gewährleisten. Bei diesen Anforderungen ist es erforderlich die Produkte in temperaturkonditionierten Gefäßen zu transportieren, die sowohl mit passiver Kühlung z. B. mit Kühlakkus als auch mit aktiver Kühltechnik z. B. mit Peltierelementen ausgestattet sein können.
Solche Transportbehältnisse werden bei professionellen Bluttransporten weitgehend ohne Komplikationen eingesetzt. Eine Schwachstelle im Transportsystem ist allerdings die Umladung der Produkte. Dabei werden die Blutprodukte in nur kurzzeitig isolierende Transportbehälter umgeladen und dem Empfänger übergeben. Die Einhaltung der Kühlkette ist in diesem Fall zumeist nicht überprüfbar und die Zeiträume, in denen die vorgeschriebenen Temperaturen eingehalten werden, sind sehr kurz.When transporting and storing blood products, it is necessary to maintain a permanent cold chain at temperatures of 2 to 6 ° C, <- 20 ° C and 20 to 24 ° C to ensure a high quality of the products that is essential for life. For these requirements, it is necessary to transport the products in temperature-conditioned vessels that can be used both with passive cooling z. B. with cold packs as well as with active cooling technology z. B. can be equipped with Peltier elements.
Such transport containers are used in professional blood transports largely without complications. A weak point in the transport system, however, is the transhipment of the products. The blood products are transhipped into only briefly insulating transport containers and handed over to the recipient. Compliance with the cold chain is usually not verifiable in this case and the periods in which the prescribed temperatures are met, are very short.

Ein weiteres Problem stellt der hausinterne Transport in Kliniken dar. Blutprodukte, die beispielsweise den Lagerort verlassen haben und für eine Operation bereitgestellt wurden, erfahren keine Temperaturkontrolle, da Sie in einfachen Isolierbehältern transportiert werden. Wenn nun ein Blutprodukt nicht verwendet wurde, ist nicht nachvollziehbar, ob das entsprechende Temperaturintervall überschritten wurde. Damit dieses Blutprodukt aber wieder eingelagert werden kann und nicht wertlos wird, ist ein aufwendiger analytischer Test des Blutproduktes notwendig. Hinzu kommt, dass viele Transportbehältnisse für Blutprodukte keinen ausreichenden Schutz- vor mechanischen Zugriffen bieten und eine Versiegelung der meisten Transportbehältnisse nicht möglich ist.Another problem is the in-house transport in clinics. Blood products, for example, have left the storage location and provided for an operation have no temperature control as they are transported in simple insulated containers. If now a blood product was not used, it is incomprehensible whether the corresponding temperature interval has been exceeded. However, for this blood product to be stored again and not worthless, a complex analytical test of the blood product is necessary. In addition, many transport containers for blood products do not provide adequate protection against mechanical access and sealing of most transport containers is not possible.

Bekannt ist es, zum Bilden eines Gliedes in einer Kette von nur bei vorgeschriebenen Temperaturintervallen ihre Güteeigenschaften bewahrenden Gütern eine Isoliereinheit mit einer Isolierschicht und einen mit einer Flüssigkeit hoher spezifischer Wärme gefüllten Hohlkörper zu verwenden. Nachteilig bei diesem Stand der Technik ist es aber, dass die Flüssigkeit hoher spezifischer Wärmekapazität direkt mit der Umhüllung des Blutproduktes in Kontakt kommt und für die Einhaltung der vorgeschriebenen Temperaturintervalle nach außen nicht sichtbar ist. Hinzu kommt, dass die Wärmespeicherkapazität der Flüssigkeit nicht ausreichend effektiv sein kann.It is known to use an insulating unit with an insulating layer and a filled with a liquid high specific heat hollow body to form a member in a chain of only at prescribed temperature intervals their goods properties preserving properties. A disadvantage of this prior art, however, is that the liquid of high specific heat capacity comes into direct contact with the envelope of the blood product and is not visible for compliance with the prescribed temperature intervals to the outside. In addition, the heat storage capacity of the fluid can not be sufficiently effective.

Die EP-A 1 006 058 offenbart einen Behälter zum Transport von Gütern bei gleichbleibenden Temperaturintervallen, wobei der Behälter, der die Güter umfasst, aus zwei komplementären jeweils doppelwandigen Zellen gebildet ist und in die Doppelwandung ein Temperiermedium gefüllt ist, das bei den gleichbleibenden Temperaturintervallen einen Phasenübergang aufweist.The EP-A 1 006 058 discloses a container for transporting goods at constant temperature intervals, wherein the container comprising the goods, is formed of two complementary double-walled cells and in the double wall, a temperature control medium is filled, which in the Constant temperature intervals has a phase transition.

Die US-A 4 470 264 offenbart einen Behälter zum Transport von Blutprodukten bei gleichbleibenden Temperaturintervallen, wobei der Behälter, der die Güter umfasst, aus zwei komplementären jeweils doppelwandigen Zellen gebildet ist. Im Behälter sind Taschen, die mit Temperiermedium gefüllt sind, das bei den gleichbleibenden Temperaturintervallen einen Phasenübergang aufweist. Zumindest ein Teil des Behälters kann transparent sein um die inneren Taschen sichtbar zu machen.The US Pat. No. 4,470,264 discloses a container for transporting blood products at constant temperature intervals, the container comprising the goods being formed of two complementary, respectively double-walled cells. In the container are pockets that are filled with tempering, which has a phase transition at the same temperature intervals. At least part of the container may be transparent to reveal the inner pockets.

Aufgabe der Erfindung ist es, ein System zum Transport von Gütern bei gleichbleibenden Temperaturen, insbesondere zum temperierten Transport von Blut- und Medizinprodukten, zu schaffen, das einzelne oder mehrere Blutprodukte komplett mechanisch schützt und diese in einem vorgeschriebenen Temperaturintervall hält. Eine weitere Aufgabe der Erfindung ist es zudem, am Behälter sichtbar zu machen, ob Temperaturintervalle eingehalten wurden.The object of the invention is to provide a system for transporting goods at constant temperatures, in particular for the temperature-controlled transport of blood and medical products, which protects completely or mechanically several or more blood products and keeps them in a prescribed temperature interval. Another object of the invention is also to make visible on the container, whether temperature intervals were met.

Die Lösung erfolgt mit einem System zum Transport von Gütern bei gleichbleibenden Temperaturen, insbesondere zum temperierten Transport von Blut- und Medizinprodukten mit den Merkmalen des Anspruchs 1. Vorteilhafte Ausgestaltungen der Erfindung sind in den Unteransprüchen dargestellt.The solution is carried out with a system for transporting goods at constant temperatures, in particular for the temperature-controlled transport of blood and medical devices The features of claim 1. Advantageous embodiments of the invention are illustrated in the subclaims.

Gemäß der Erfindung weist ein System zum Transport von Gütern bei gleichbleibenden Temperaturen, insbesondere zum Transport von Blut- und Medizinprodukten, einen Aufbewahr-, Schutz- und Transportbehälter für leicht verderbliche Produkte auf mit einer Doppelwandung, der von innen mit einem flüssigen oder festen Latentwärmespeicher gefüllt ist, und gleichzeitig eine isolierende Wirkung aufweist.According to the invention, a system for transporting goods at constant temperatures, in particular for the transport of blood and medical products, a storage, protection and transport container for perishable products with a double wall filled from the inside with a liquid or solid latent heat storage is, and at the same time has an insulating effect.

Gemäß einer vorteilhaften Ausgestaltung der Erfindung ist der Transportbehälter so ausgeführt, daß sich zwei gleiche Zellen über vorzugsweise mehrere Verschnappungen auf den Längsseiten verbinden lassen. Dabei entsteht ein von äußerer Einwirkung mechanisch geschützter Hohlraum zwischen den beiden Behältern, der für die Aufbewahrung von Blutprodukten gedacht ist.According to an advantageous embodiment of the invention, the transport container is designed so that it is possible to connect two identical cells via preferably several snaps on the long sides. The result is a mechanically protected by external impact cavity between the two containers, which is intended for the storage of blood products.

Gemäß einer weiteren vorteilhaften Ausgestaltung der Erfindung ist der Behälter aus zwei komplementären, jeweils doppelwandigen Zellen und einem ebenfalls komplementären, doppelwandigen Ring gebildet, die sich an Längsseiten über Verschnappungen verbinden lassen. Der mit Verschnappungen versehene komplementäre, doppelwandige Ring erlaubt es den zu umhüllenden Innenraum zu vergrößern. Als Boden und als Deckel dienen die zwei komplementären, jeweils doppelwandigen Zellen. Der doppelwandige Ring ist ebenfalls mit einer Flüssigkeit gefüllt, die als Temperaturspeicher fungiert und bei ihrem Phasenwechsel hohe Energiemengen abgeben oder aufnehmen kann.According to a further advantageous embodiment of the invention, the container of two complementary, each double-walled cells and a likewise complementary, double-walled ring is formed, which can be connected to longitudinal sides via snaps. The complementary, double-walled ring with snaps allows the interior to be enveloped to be enlarged. The two complementary, double-walled cells serve as the bottom and lid. The double-walled ring is also filled with a liquid that acts as a temperature storage and can deliver or absorb large amounts of energy during their phase change.

Gemäß einer weiteren vorteilhaften Ausgestaltung der Erfindung ist die Doppelwandung eines Elementes mit einem Latentwärmespeicher, der einen Schmelzpunkt zwischen 2 bis 8 °C aufweist, insbesondere Paraffin oder auf Trägermaterialien immobilisiertes Paraffin, gefüllt, um ein Temperaturniveau von 2 bis 6 °C im Innenraum konstant zu halten. Der Behälter ist damit besonders gut für die Aufbewahrung und den Transport von Erythrozytenkonzentraten und anderen Blutprodukten, Antikörpern, Zellen, bzw. biotechnologisch hergestellter Pharma-Produkte, die zwischen 2 bis 6 °C transportiert werden müssen, geeignet.According to a further advantageous embodiment of the invention, the double wall of an element with a latent heat storage having a melting point between 2 to 8 ° C, in particular paraffin or immobilized on substrates paraffin, filled to a Temperature level of 2 to 6 ° C in the interior to keep constant. The container is thus particularly well suited for the storage and transport of red blood cell concentrates and other blood products, antibodies, cells, or biotechnologically produced pharmaceutical products that must be transported between 2 to 6 ° C, suitable.

Gemäß einer weiteren vorteilhaften Ausgestaltung der Erfindung werden zur Stabilisierung von Temperaturbereichen oberhalb 0° C n-Kohlenwasserstoffketten verwendet, nämlich n-Paraffine, die der Summenformel CnH2n+2 genügen.According to a further advantageous embodiment of the invention, n-hydrocarbon chains are used to stabilize temperature ranges above 0 ° C, namely n-paraffins that satisfy the molecular formula C n H 2n + 2 .

Gemäß einer anderen vorteilhaften Ausgestaltung der Erfindung ist der Behälter mit einer wässrigen Salzlösung oder einem Ethanol-Wassergemisch als Temperiermedium gefüllt, das zwischen - 20° C und - 40° C einen Phasenübergang zwischen flüssig und fest aufweist.According to another advantageous embodiment of the invention, the container is filled with an aqueous salt solution or an ethanol-water mixture as tempering, which has a phase transition between liquid and solid between - 20 ° C and - 40 ° C.

Gemäß einer anderen vorteilhaften Ausgestaltung der Erfindung ist die Doppelwandung eines Elementes mit einem Latentwärmespeicher, der einen Schmelzpunkt zwischen 20 bis 24° C aufweist, insbesondere mit Paraffin, auf Trägermaterialien immobilisiertes Paraffin oder einer Buthandiol-Wassermischung, gefüllt, um ein Temperaturniveau von 20 und 24° C im Innenraum konstant zu halten. Der Behälter ist damit besonders gut für die Aufbewahrung und den Transport von Thrombozyten und anderen Blutprodukten, die zwischen 20 und 24° C transportiert werden müssen, geeignet.According to another advantageous embodiment of the invention, the double wall of an element with a latent heat storage having a melting point between 20 to 24 ° C, in particular paraffin, immobilized on substrates paraffin or a Buthandiol-water mixture filled to a temperature level of 20 and 24 ° C in the interior to keep constant. The container is thus particularly well suited for the storage and transport of platelets and other blood products that must be transported between 20 and 24 ° C, suitable.

Gemäß einer weiteren vorteilhaften Ausgestaltung der Erfindung ist das Material der Doppelwand transparent, insbesondere transparenter Kunststoff, so daß der Aggregatzustand des Latentwärmespeichermaterials sichtbar wird. Der Behälter ist damit besonders gut für die Kontrolle des Temperaturverlaufs und somit der Kühlkette geeignet.According to a further advantageous embodiment of the invention, the material of the double wall is transparent, in particular transparent plastic, so that the state of aggregation of the latent heat storage material is visible. The container is therefore particularly well suited for the control of the temperature profile and thus the cold chain.

Gemäß einer weiteren vorteilhaften Ausgestaltung der Erfindung ist die Doppelwandung aus diffusionsdichten Kunststoffen, wie Polyamid, z. B. Kevlar, oder aus Metallen wie Aluminium, Stahl oder Gusseisen gefertigt.According to a further advantageous embodiment of the invention, the double wall of diffusion-tight plastics, such as polyamide, z. As Kevlar, or made of metals such as aluminum, steel or cast iron.

Gemäß einer weiteren vorteilhaften Ausgestaltung der Erfindung ist der Transportbehälter stapelbar, da er auf der Rückseite arretierende Verbindungselemente aufweist.According to a further advantageous embodiment of the invention, the transport container is stackable, since it has on the back arresting fasteners.

Gemäß weiterer vorteilhafter Ausgestaltungen der Erfindung sind jeweils mindestens zwei mit der Verschnappung zum Transportbehälter verbundene Elemente versiegelbar oder verplombbar.According to further advantageous embodiments of the invention, at least two elements connected to the snap to the transport container are each sealable or sealable.

Gemäß einer weiteren vorteilhaften Ausgestaltung der Erfindung weist der Behälter mindestens eine Öse auf zum verplomben, so dass sich unbefugtes Öffnen verhindern oder erkennen läßt.According to a further advantageous embodiment of the invention, the container has at least one eyelet to seal, so that can prevent or detect unauthorized opening.

Gemäß einer weiteren vorteilhaften Ausgestaltung der Erfindung sind die Elemente des Aufbewahr-, Schutz- und Transportbehälters mit Nut und Feder versehen, so daß der Wärmedurchgang minimiert wird.According to a further advantageous embodiment of the invention, the elements of the storage, protection and transport container are provided with tongue and groove, so that the heat transfer is minimized.

Gemäß einer weiteren vorteilhaften Ausgestaltung der Erfindung sind die Elemente des Aufbewahr-, Schutz- und Transportbehälters mit einem Scharnier verbunden.According to a further advantageous embodiment of the invention, the elements of the storage, protection and transport container are connected to a hinge.

Gemäß einer weiteren vorteilhaften Ausgestaltung der Erfindung sind die Elemente des Aufbewahr-, Schutz- und Transportbehälters mit einem Tragegriff versehen.According to a further advantageous embodiment of the invention, the elements of the storage, protection and transport container are provided with a carrying handle.

Gemäß einer weiteren vorteilhaften Ausgestaltung der Erfindung ist der Behälter innen mit einem Thermometer, insbesondere einem Klebstreifenthermometer oder einem Flüssigkristallthermometer und/oder elektronisch auslesbarem Temperaturaufzeichnungsgerät ausgestattet.According to a further advantageous embodiment of the invention, the container is internally equipped with a thermometer, in particular an adhesive tape thermometer or a liquid crystal thermometer and / or electronically readable temperature recording device.

Weitere Merkmale, Einzelheiten und Vorzüge der Erfindung sind in den Zeichnungen dargestellt und werden im folgenden beschrieben. Es zeigen:

Fig. 1:
eine perspektivische Innenansicht eines Elementes des Aufbewahr-, Schutz- und Transportbehälters gemäß der Erfindung,
Fig. 2:
eine perspektivische Außenansicht eines zum Element aus Fig. 1 komplementären Elementes des Aufbewahr-, Schutz- und Transportbehälters gemäß der Erfindung,
Fig. 3:
eine perspektivische Ansicht eines zu den Elementen aus Fig. 1 und 2 komplementären Rings für den Aufbewahr-, Schutz- und Transportbehälter gemäß der Erfindung, und
Fig. 4:
eine perspektivische Außenansicht eines Aufbewahr-Schutz- und Transportbehälters gemäß der Erfindung.
Further features, details and advantages of the invention are illustrated in the drawings and will be described below. Show it:
Fig. 1:
an interior perspective view of an element of the storage, protection and transport container according to the invention,
Fig. 2:
an external perspective view of the element Fig. 1 complementary element of the storage, protection and transport container according to the invention,
3:
a perspective view of one of the elements Fig. 1 and 2 complementary ring for the storage, protection and transport container according to the invention, and
4:
an external perspective view of a storage protection and transport container according to the invention.

Fig. 1: Das System zum Transport von Gütern bei gleichbleibenden Temperaturen enthält ein eine Zelle bildendes Element 1 eines Aufbewahr-, Schutz- und Transportbehälters, das mit einem ebenfalls eine Zelle bildenden, zweiten gleichen Element 10 (Fig. 2) über Verschnappungen 2 verbunden werden kann. Das Element 1 bildet mit seiner Innenseite und dem aufgesetzten zweiten gleichen Element 10 so einen Hohlraum 3, der durch eine jeweils doppelte Wandung der Elemente 1 und 10 und durch Nut 4 und Feder 5 an Verbindungskanten 6 von der äußeren Umgebung abgeschirmt ist. Der Hohlraum 3 dient zur Aufnahme von Blutprodukten (nicht dargestellt) oder anderen Produkten, wie Antikörpern, Zellen, bzw. biotechnologisch hergestellter Pharma-Produkte, die sich in Ihrer Orginalverpackung befinden. Fig. 1 The system for transporting goods at constant temperatures comprises a cell-forming element 1 of a storage, protection and transport container, which is connected to a second, same element 10 (also forming a cell). Fig. 2 ) can be connected via snaps 2. The element 1 forms with its inner side and the attached second same element 10 so a cavity 3, which is shielded by a respective double wall of the elements 1 and 10 and by groove 4 and spring 5 at joint edges 6 from the outside environment. The cavity 3 serves to accommodate blood products (not shown) or other products, such as antibodies, cells, or biotechnologically produced pharmaceutical products, which are in their original packaging.

Fig. 2: Die Elemente 1 und 10 enthalten jeweils einen flüssigen oder festen Latentwärmespeicher innerhalb der doppelten Wandung. Die Elemente weisen auf der Aussenseite Einbuchtungen 8 und Vorsprünge 7 auf, so daß eine Arretierung und damit eine Stapelbarkeit gewährleistet ist. Mit Hilfe einer Außenleiste (nicht dargestellt) lassen sich zwei Elemente miteinander verplomben. Fig. 2 The elements 1 and 10 each contain a liquid or solid latent heat storage within the double wall. The elements have on the outside recesses 8 and projections 7, so that a lock and thus a stackability is guaranteed. With the help of an outer strip (not shown), two elements can be sealed together.

Fig. 3: Entsprechende Merkmale sind mit den Bezugszeichen aus Fig. 1 und 2 bezeichnet. Ein einen Ring bildendes Element 20 zur Vergrößerung des Hohlraums 3 des Aufbewahr-, Schutz- und Transportbehälters ist entsprechend den Elementen 1 und 10 mit doppelter Wandung ausgestattet und komplementär zu den Elementen 1 und 10, mit denen es durch Nut 4 und Feder 5 an Verbindungskanten 6 verbunden werden kann. Fig. 3 Corresponding features are indicated by the reference numerals Fig. 1 and 2 designated. A ring-forming element 20 for enlarging the cavity 3 of the storage, protection and transport container is equipped according to the double-walled elements 1 and 10 and complementary to the elements 1 and 10 with which it passes through groove 4 and tongue 5 at joint edges 6 can be connected.

Fig. 4: Entsprechende Merkmale sind mit den Bezugszeichen aus Fig. 1, 2 und 3 bezeichnet. Das System zum Transport von Gütern bei gleich-bleibenden Temperaturen ist ausgebildet als vergrößerter Aufbewahr-, Schutz-und Transportbehälter mit dem eine Zelle bildenden Element 1, dem ebenfalls eine Zelle bildenden, zweiten gleichen Element 10 und dem einen Ring bildenden, zu den Elementen 1 und 10 jeweils komplementären Element 20, die jeweils über Verschnappungen 2 mit dem Element 20 verbunden sind. Fig. 4 Corresponding features are indicated by the reference numerals Fig. 1 . 2 and 3 designated. The system for transporting goods at constant temperatures is designed as an enlarged storage, protection and transport container with the cell-forming element 1, which also forms a cell, second same element 10 and the one ring forming, to the elements. 1 and 10 each complementary element 20, which are each connected via snaps 2 with the element 20.

Die doppelte Wandung der Elemente 1, 10 und 20 ist aus einem isolierenden, transparenten Plastikmaterial oder aus diffusionsdichten Kunststoffen, wie Polyamid, z. B. Kevlar, oder aus Metallen wie Aluminium, Stahl oder Gusseisen gefertigt.The double wall of the elements 1, 10 and 20 is made of an insulating, transparent plastic material or of diffusion-tight plastics, such as polyamide, z. As Kevlar, or made of metals such as aluminum, steel or cast iron.

Elemente 1, 10 und 20 sind jeweils mit verschließbaren Öffnungen (nicht dargestellt) zum Befüllen oder Leeren der die Elemente 1, 10 und 20 bildenden Zellen mit einem Latentwärmespeicher, der einen Schmelzpunkt zwischen 20° C bis 24 °C, 2° C bis 6 °C und -20° C bis -30° C aufweist, bis 24 °C, 2° C bis 6 °C und -20° C bis -40° C aufweist, insbesondere mit Paraffin, auf Trägermaterialien immobilisiertem Paraffin oder einer Buthandiol-Wassermischung, einer wässrigen Salzlösung oder einem Ethanol-Wassergemisch, versehen. Alternativ können zur Stabilisierung von Temperaturbereichen oberhalb 0° C n-Kohlenwasserstoffketten verwendet werden, nämlich n-Paraffine, die der Summenformel CnH2n+2 genügen.Elements 1, 10 and 20 are each with closable openings (not shown) for filling or emptying the cells forming the elements 1, 10 and 20 with a latent heat storage having a melting point between 20 ° C to 24 ° C, 2 ° C to 6 ° C and -20 ° C to -30 ° C, up to 24 ° C, 2 ° C to 6 ° C and -20 ° C to -40 ° C, in particular with paraffin, on substrates immobilized paraffin or a butanediol-water mixture, an aqueous salt solution or an ethanol-water mixture provided. Alternatively, to stabilize temperature ranges above 0 ° C, n-hydrocarbon chains can be used, namely n-paraffins which satisfy the molecular formula C n H 2n + 2 .

Transparente Wandungen des Aufbewahr-, Schutz- und Transportbehälters lassen am gefrorenen Zustand des Latentwärmespeichers erkennen, daß das entsprechende Temperaturniveau eingehalten wurde. Somit lassen sich problemlos Blutprodukte wie beispielsweise Erythrozytenkonzentrate und Thrombozyten bei Temperaturen von 2 bis 6 °C und 20 bis 24 °C transportieren und handhaben.Transparent walls of the storage, protection and transport container can be seen on the frozen state of the latent heat storage that the appropriate temperature level has been maintained. Thus, blood products such as red cell concentrates and platelets can be easily transported and handled at temperatures of 2 to 6 ° C and 20 to 24 ° C.

Der Behälter aus zwei oder drei komplementären, jeweils doppelwandigen Zellen umschließt den für die Aufnahme der Güter vorgesehenen Hohlraum 3, der ausgestattet ist mit einem Thermometer (nicht dargestellt), insbesondere einem Klebestreifenthermometer, einem Flüssigkristallthermometer und/oder elektronisch auslesbarem Temperaturaufzeichnungsgerät, das für die ausgewählten Intervalle von 20° C bis 24 °C, 2° C bis 6 °C und -20° C bis -30° C ausgelegt ist, innerhalb derer die Temperaturen gleich bleiben sollen.The container of two or three complementary, each double-walled cells enclosing the intended for receiving the goods cavity 3, which is equipped with a thermometer (not shown), in particular an adhesive tape thermometer, a liquid crystal thermometer and / or electronically readable temperature recording device, for the selected From 20 ° C to 24 ° C, 2 ° C to 6 ° C and -20 ° C to -30 ° C, within which the temperatures should remain the same.

Der Behälter aus zwei oder drei komplementären, jeweils doppelwandigen Zellen ist mit mindestens einer Öse (nicht dargestellt) versehen, die es erlaubt zwei komplementäre Zellen mit Hilfe einer Plombe zu versiegeln, so dass sich unbefugtes Öffnen verhindern oder erkennen läßt.The container of two or three complementary, each double-walled cells is provided with at least one eyelet (not shown), which allows sealing two complementary cells by means of a seal, so that can prevent or detect unauthorized opening.

Claims (16)

  1. System for transporting goods at constant intervals of temperature, particularly for blood products, with a container, confining these goods, the container being formed with two complementary, respectively double-walled cells (1, 10) and the double walls being filled with a tempering medium having a phase transition at the constant intervals of temperature, characterized in that the complementary cells (1, 10) have the same shape, the double walls are made of transparent, undiffusible synthetic material and in that at least one snap (2) is provided allowing the coupling of the cells (1, 10) along their longitudinal sides.
  2. System according to claim 1, characterized in that the container is formed with two likewise, respectively double-walled cells (1, 10) and a complementary double-walled ring (20) allowing the coupling along their longitudinal sides.
  3. System according to claim 1, characterized in that the container is filled with paraffin or paraffin immobilised in carrier materials as a tempering medium.
  4. System according to claim 3, characterized in that the paraffin has a phase transition from liquid to solid between 2° C and 8° C or 20° C and 24° C.
  5. System according to claim 3, characterized in that above 0° C chains of n-hydrocarbon are used, i. e. n-paraffins corresponding to the sum-formula CnH2n+2.
  6. System according to claim 1, characterized in that the container is filled with a watery salt solution or an ethanol water mixture as tempering medium having between 20° C and -40° C a phase transition between liquid and solid.
  7. System according to claim 1, characterized in that the container is filled with a butanethiol water mixture as tempering medium having between 20° C and 24° C a phase transition between liquid and solid.
  8. System according to claim 1, characterized in that the double walls are provided with coupling elements locking towards outside.
  9. System according to claim 1, characterized in that the container with two likewise, respectively double-walled cells (1, 10) is sealable with snaps at the longitudinal sides.
  10. System according to claim 2, characterized in that the container with two likewise, respectively double-walled cells (1, 10) and the complementary double-walled ring (20) is sealable with snaps at the longitudinal sides (2).
  11. System according to claim 1 or 10, characterized in that the container is provided with at least one lug for sealing.
  12. System according to claim 1, characterized in that the container with two likewise, respectively double-walled cells (1, 10) is provided with groove (4) and tongue (5) at the longitudinal sides (2).
  13. System according to claim 2, characterized in that the container with two likewise, respectively double-walled cells (1, 10) and the as well complementary double-walled ring (20) is provided with groove (4) and tongue (5) at the longitudinal sides (2).
  14. System according to claim 1 or 2, characterized in that the likewise, respectively double-walled cells (1, 10) and/or the as well complementary double-walled ring (20) are coupled pivotally to each other via a hinge.
  15. System according to claim 1 or 2, characterized in that the container is provided with a carrying grip.
  16. System according to claim 1 or 2, characterized in that the container with two or three likewise, respectively double-walled cells (1, 10) confines a hollow space (3) provided for the reception of the goods being equipped with a thermometer, particularly an adhesive tape thermometer, a liquid crystal thermometer and/or an electronically readable temperature recording device.
EP01124070A 2001-10-10 2001-10-10 System for transporting goods at constant temperature Expired - Lifetime EP1302410B1 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
DE50114568T DE50114568D1 (en) 2001-10-10 2001-10-10 System for transporting goods at constant temperatures
AT01124070T ATE417002T1 (en) 2001-10-10 2001-10-10 SYSTEM FOR TRANSPORTING GOODS AT CONSTANT TEMPERATURES
ES01124070T ES2320409T3 (en) 2001-10-10 2001-10-10 SYSTEM FOR THE TRANSPORT OF GOODS TO CONSTANT TEMPERATURE.
EP01124070A EP1302410B1 (en) 2001-10-10 2001-10-10 System for transporting goods at constant temperature
DK01124070T DK1302410T3 (en) 2001-10-10 2001-10-10 System for transporting goods at constant temperature
US10/022,406 US20030072687A1 (en) 2001-10-10 2001-12-20 System to transport goods at consistent temperatures

Applications Claiming Priority (1)

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EP01124070A EP1302410B1 (en) 2001-10-10 2001-10-10 System for transporting goods at constant temperature

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EP1302410B1 true EP1302410B1 (en) 2008-12-10

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EP (1) EP1302410B1 (en)
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DE (1) DE50114568D1 (en)
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ES (1) ES2320409T3 (en)

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US20030072687A1 (en) 2003-04-17
ATE417002T1 (en) 2008-12-15
DE50114568D1 (en) 2009-01-22
ES2320409T3 (en) 2009-05-22
EP1302410A1 (en) 2003-04-16
DK1302410T3 (en) 2009-04-06

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