EP1268526A4 - Molecules d'acide nucleique specifiques de la prostate ou des testicules, polypeptides, techniques de diagnostic, et traitement therapeutique - Google Patents

Molecules d'acide nucleique specifiques de la prostate ou des testicules, polypeptides, techniques de diagnostic, et traitement therapeutique

Info

Publication number
EP1268526A4
EP1268526A4 EP01922630A EP01922630A EP1268526A4 EP 1268526 A4 EP1268526 A4 EP 1268526A4 EP 01922630 A EP01922630 A EP 01922630A EP 01922630 A EP01922630 A EP 01922630A EP 1268526 A4 EP1268526 A4 EP 1268526A4
Authority
EP
European Patent Office
Prior art keywords
specific
testis
polypeptides
diagnostic
nucleic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP01922630A
Other languages
German (de)
English (en)
Other versions
EP1268526A2 (fr
Inventor
Fahri Saatcioglu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of EP1268526A2 publication Critical patent/EP1268526A2/fr
Publication of EP1268526A4 publication Critical patent/EP1268526A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/07Animals genetically altered by homologous recombination
    • A01K2217/075Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP01922630A 2000-03-24 2001-03-23 Molecules d'acide nucleique specifiques de la prostate ou des testicules, polypeptides, techniques de diagnostic, et traitement therapeutique Withdrawn EP1268526A4 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US19192900P 2000-03-24 2000-03-24
US191929P 2000-03-24
PCT/US2001/009410 WO2001072962A2 (fr) 2000-03-24 2001-03-23 Molecules d'acide nucleique specifiques de la prostate ou des testicules, polypeptides, techniques de diagnostic, et traitement therapeutique

Publications (2)

Publication Number Publication Date
EP1268526A2 EP1268526A2 (fr) 2003-01-02
EP1268526A4 true EP1268526A4 (fr) 2004-09-08

Family

ID=22707491

Family Applications (1)

Application Number Title Priority Date Filing Date
EP01922630A Withdrawn EP1268526A4 (fr) 2000-03-24 2001-03-23 Molecules d'acide nucleique specifiques de la prostate ou des testicules, polypeptides, techniques de diagnostic, et traitement therapeutique

Country Status (5)

Country Link
EP (1) EP1268526A4 (fr)
JP (1) JP2004521602A (fr)
AU (2) AU2001249411B2 (fr)
CA (1) CA2403637A1 (fr)
WO (1) WO2001072962A2 (fr)

Families Citing this family (92)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030149531A1 (en) 2000-12-06 2003-08-07 Hubert Rene S. Serpentine transmembrane antigens expressed in human cancers and uses thereof
DK1086223T3 (da) 1998-06-01 2009-11-30 Agensys Inc Nye serpentintransmembranantigener udtrykt i humane cancerformer og anvendelser deraf
US20040141975A1 (en) 1998-06-01 2004-07-22 Raitano Arthur B. Nucleic acid and corresponding protein entitled 98P4B6 useful in treatment and detection of cancer
US20060052321A1 (en) 2002-04-05 2006-03-09 Raitano Arthur B Nucleic acid and corresponding protein entitled 98P4B6 useful in treatment and detection of cancer
US6833438B1 (en) 1999-06-01 2004-12-21 Agensys, Inc. Serpentine transmembrane antigens expressed in human cancers and uses thereof
US20040048798A1 (en) * 1999-06-01 2004-03-11 Raitano Arthur B. Nucleic acid and corresponding protein entitle 98P4B6 useful in treatment and detection of cancer
US6835812B1 (en) 1999-04-29 2004-12-28 University Of Tennessee Research Corporation Human p-Hyde proteins
EP1328151A4 (fr) * 1999-04-29 2004-06-16 Univ Tennessee Res Corp Acides nucleiques isoles de la famille p-hyde, proteines p-hyde et procede pour induire la susceptibilite a l'induction de la mort cellulaire programmee pendant le cancer
US7611892B2 (en) 2000-03-24 2009-11-03 President And Fellows Of Harvard College Prostate-specific or testis-specific nucleic acid molecules, polypeptides, and diagnostic and therapeutic methods
GB2379660A (en) * 2001-01-30 2003-03-19 Aeomica Inc Human GTP-Rho binding protein 2
EP1231216A3 (fr) * 2001-01-30 2004-03-17 Aeomica, Inc. Protéine humaine qui se lie au gtp-rho
US7494646B2 (en) 2001-09-06 2009-02-24 Agensys, Inc. Antibodies and molecules derived therefrom that bind to STEAP-1 proteins
EP2287186B1 (fr) 2001-09-06 2014-12-31 Agensys, Inc. Acide nucléique et protéine corréspondante designés par STEAP-1 utiles dans le traitement et la détection du cancer
JP2005534287A (ja) * 2002-04-05 2005-11-17 アジェンシス, インコーポレイテッド 癌の処置および検出において有用な98p4b6との名称の核酸および対応するタンパク質
JP5840351B2 (ja) * 2002-09-06 2016-01-06 アジェンシス,インコーポレイテッド 癌の処置および検出において有用な98p4b6と称される、核酸および対応タンパク質
EP1725249B1 (fr) 2003-11-06 2014-01-08 Seattle Genetics, Inc. Composes de monomethylvaline capables de conjugaison aux ligands
GB0326834D0 (en) * 2003-11-18 2003-12-24 Celltech R&D Ltd A protein involved in lung cancer
TWI238677B (en) 2003-12-25 2005-08-21 Fujitsu Ltd Organic EL element, organic EL display, process for fabricating organic EL element, and device for fabricating organic EL element
US8008442B2 (en) 2004-04-22 2011-08-30 Agensys, Inc. Antibodies and molecules derived therefrom that bind to STEAP-1 proteins
JP5234734B2 (ja) 2004-06-01 2013-07-10 ジェネンテック, インコーポレイテッド 抗体−薬物結合体および方法
ES2669510T3 (es) 2004-09-23 2018-05-28 Genentech, Inc. Anticuerpos y conjugados modificados por ingeniería genética con cisteína
US20100111856A1 (en) 2004-09-23 2010-05-06 Herman Gill Zirconium-radiolabeled, cysteine engineered antibody conjugates
AU2005246090A1 (en) * 2005-02-22 2005-12-01 Biomedisinsk Innovasjon As STAMP2 nucleic acid molecules, polypeptides, and diagnostic and therapeutic methods
RU2483080C2 (ru) 2006-10-27 2013-05-27 Дженентек, Инк. Антитела и иммуноконъюгаты и их применение
EP2292089A1 (fr) * 2008-01-11 2011-03-09 Astellas Pharma Inc. Modèle animal ayant à la fois une douleur dans les testicules ou des actions d'inconfort en relation aux testicules et une miction fréquente
IN2012DN03025A (fr) 2009-09-09 2015-07-31 Ct Se Llc
EA024730B1 (ru) 2010-04-15 2016-10-31 Медимьюн Лимитед Пирролбензодиазепиновые соединения, их конъюгаты, фармацевтические композиции, содержащие указанные конъюгаты, и применение указанных конъюгатов
US9000130B2 (en) 2010-06-08 2015-04-07 Genentech, Inc. Cysteine engineered antibodies and conjugates
JP5889912B2 (ja) 2010-11-17 2016-03-22 ジェネンテック, インコーポレイテッド アラニニルメイタンシノール抗体コンジュゲート
CA2833212C (fr) 2011-05-12 2020-06-09 Genentech, Inc. Reaction multiple de surveillance du procede lc-ms/ms pour detecter les anticorps therapeutiques dans les echantillons d'animaux par des peptides de signature du cadre
ES2556584T3 (es) 2011-10-14 2016-01-19 Medimmune Limited Pirrolobenzodiazepinas y conjugados de las mismas
WO2013130093A1 (fr) 2012-03-02 2013-09-06 Genentech, Inc. Biomarqueurs pour un traitement à base de composés chimiothérapeutiques anti-tubuline
PT2766048E (pt) 2012-10-12 2015-02-25 Spirogen Sarl Pirrolobenzodiazepinas e conjugados das mesmas
EP2906250B1 (fr) 2012-10-12 2018-05-30 ADC Therapeutics SA Conjugués pyrrolobenzodiazepine-anticorps anti-psma
NZ707543A (en) 2012-10-12 2018-09-28 Adc Therapeutics Sa Pyrrolobenzodiazepine-antibody conjugates
ES2649990T3 (es) 2012-10-12 2018-01-16 Medimmune Limited Conjugados de anticuerpos anti-CD22-pirrolobenzodiazepinas
ES2660029T3 (es) 2012-10-12 2018-03-20 Medimmune Limited Conjugados de anticuerpo-pirrolobenzodiazepinas
KR101995619B1 (ko) 2012-10-12 2019-07-03 에이디씨 테라퓨틱스 에스에이 피롤로벤조디아제핀-항체 컨주게이트
SI2906253T1 (sl) 2012-10-12 2018-11-30 Adc Therapeutics Sa Konjugati pirolobenzodiazepin-protitelo proti PSMA
WO2014096365A1 (fr) 2012-12-21 2014-06-26 Spirogen Sàrl Dimères de pyrrolobenzodiazépines asymétriques à utiliser dans le traitement de maladies prolifératives et auto-immunes
WO2014096368A1 (fr) 2012-12-21 2014-06-26 Spirogen Sàrl Pyrrolobenzodiazépines et conjugués associés
US9649390B2 (en) 2013-03-13 2017-05-16 Medimmune Limited Pyrrolobenzodiazepines and conjugates thereof
CN105209077B (zh) 2013-03-13 2019-06-11 麦迪穆有限责任公司 吡咯并苯并二氮杂卓以及其结合物
EP2968596B1 (fr) 2013-03-13 2019-03-06 Medimmune Limited Pyrrolobenzodiazépines et leurs conjugués
CA2918139A1 (fr) 2013-08-12 2015-02-19 Genentech, Inc. Conjugues anticorps-medicament dimerique 1-(chloromethyl)-2,3-dihydro-1 h-benzo [e]indole, et methodes d'utilisation et de traitement
EP3054983B1 (fr) 2013-10-11 2019-03-20 Medimmune Limited Conjugués anticorps-pyrrolobenzodiazépines
WO2015052535A1 (fr) 2013-10-11 2015-04-16 Spirogen Sàrl Conjugués anticorps-pyrrolobenzodiazépine
WO2015052534A1 (fr) 2013-10-11 2015-04-16 Spirogen Sàrl Conjugués anticorps-pyrrolobenzodiazépine
GB201317982D0 (en) 2013-10-11 2013-11-27 Spirogen Sarl Pyrrolobenzodiazepines and conjugates thereof
JP6671292B2 (ja) 2013-12-16 2020-03-25 ジェネンテック, インコーポレイテッド ペプチド模倣化合物及びその抗体−薬物コンジュゲート
CR20160271A (es) 2013-12-16 2016-12-02 Genentech Inc Compuestos peptidométicos y sus conjugados de anticuerpo-fármaco
MX2016007578A (es) 2013-12-16 2016-10-03 Genentech Inc Compuestos de conjugado anticuerpo-farmaco dimerico de 1-(clorometil)-2,3-dihidro-1h-benzo [e] indol, y metodos de uso y tratamiento.
WO2016037644A1 (fr) 2014-09-10 2016-03-17 Medimmune Limited Pyrrolobenzodiazépines et leurs conjugués
CA2957354A1 (fr) 2014-09-12 2016-03-17 Genentech, Inc. Anticorps et conjugues modifies genetiquement avec de la cysteine
GB201416112D0 (en) 2014-09-12 2014-10-29 Medimmune Ltd Pyrrolobenzodiazepines and conjugates thereof
WO2016040825A1 (fr) 2014-09-12 2016-03-17 Genentech, Inc. Intermédiaires disulfure d'anthracycline, conjugué anticorps-médicaments et procédés
US20160074527A1 (en) 2014-09-17 2016-03-17 Genentech, Inc. Pyrrolobenzodiazepines and antibody disulfide conjugates thereof
US10780096B2 (en) 2014-11-25 2020-09-22 Adc Therapeutics Sa Pyrrolobenzodiazepine-antibody conjugates
MX2017007169A (es) 2014-12-03 2018-05-02 Genentech Inc Compuestos de amina cuaternaria y conjugados de anticuerpofármaco de los mismos.
GB201506411D0 (en) 2015-04-15 2015-05-27 Bergenbio As Humanized anti-axl antibodies
GB201506402D0 (en) 2015-04-15 2015-05-27 Berkel Patricius H C Van And Howard Philip W Site-specific antibody-drug conjugates
MA43345A (fr) 2015-10-02 2018-08-08 Hoffmann La Roche Conjugués anticorps-médicaments de pyrrolobenzodiazépine et méthodes d'utilisation
MA43354A (fr) 2015-10-16 2018-08-22 Genentech Inc Conjugués médicamenteux à pont disulfure encombré
MA45326A (fr) 2015-10-20 2018-08-29 Genentech Inc Conjugués calichéamicine-anticorps-médicament et procédés d'utilisation
GB201601431D0 (en) 2016-01-26 2016-03-09 Medimmune Ltd Pyrrolobenzodiazepines
GB201602359D0 (en) 2016-02-10 2016-03-23 Medimmune Ltd Pyrrolobenzodiazepine Conjugates
GB201602356D0 (en) 2016-02-10 2016-03-23 Medimmune Ltd Pyrrolobenzodiazepine Conjugates
CN108700598A (zh) 2016-03-25 2018-10-23 豪夫迈·罗氏有限公司 多路总抗体和抗体缀合的药物量化测定法
GB201607478D0 (en) 2016-04-29 2016-06-15 Medimmune Ltd Pyrrolobenzodiazepine Conjugates
PL3458101T3 (pl) 2016-05-20 2021-05-31 F. Hoffmann-La Roche Ag Koniugaty PROTAC-przeciwciało i sposoby ich stosowania
EP3465221B1 (fr) 2016-05-27 2020-07-22 H. Hoffnabb-La Roche Ag Procédé bioanalytique pour la caractérisation de conjugués anticorps-médicament spécifiques d'un site
JP7043425B2 (ja) 2016-06-06 2022-03-29 ジェネンテック, インコーポレイテッド シルベストロール抗体-薬物コンジュゲート及び使用方法
EP3496763A1 (fr) 2016-08-11 2019-06-19 Genentech, Inc. Promédicaments de pyrrolobenzodiazépine et conjugués d'anticorps de ceux-ci
JP7050770B2 (ja) 2016-10-05 2022-04-08 エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト 抗体薬物コンジュゲートの調製方法
GB201617466D0 (en) 2016-10-14 2016-11-30 Medimmune Ltd Pyrrolobenzodiazepine conjugates
GB201702031D0 (en) 2017-02-08 2017-03-22 Medlmmune Ltd Pyrrolobenzodiazepine-antibody conjugates
JP6671555B2 (ja) 2017-02-08 2020-03-25 アーデーセー セラピューティクス ソシエテ アノニム ピロロベンゾジアゼピン抗体複合体
WO2018184966A1 (fr) 2017-04-03 2018-10-11 F. Hoffmann-La Roche Ag Anticorps se liant à steap-1
WO2018192944A1 (fr) 2017-04-18 2018-10-25 Medimmune Limited Conjugués de pyrrolobenzodiazépine
EP3612234B1 (fr) 2017-04-20 2024-03-13 ADC Therapeutics SA Polythérapie avec un conjugué anticorps anti-axl-médicament
JP7145891B2 (ja) 2017-06-14 2022-10-03 アーデーセー セラピューティクス ソシエテ アノニム 抗cd19 adcを投与するための投与レジメ
EA039276B1 (ru) 2017-08-18 2021-12-27 Медимьюн Лимитед Пирролобензодиазепиновые конъюгаты
BR112020004307A2 (pt) 2017-09-20 2020-11-10 Ph Pharma Co., Ltd. análogos de tailanestatina
GB201803342D0 (en) 2018-03-01 2018-04-18 Medimmune Ltd Methods
GB201806022D0 (en) 2018-04-12 2018-05-30 Medimmune Ltd Pyrrolobenzodiazepines and conjugates thereof
GB201814281D0 (en) 2018-09-03 2018-10-17 Femtogenix Ltd Cytotoxic agents
AU2019365238A1 (en) 2018-10-24 2021-05-13 F. Hoffmann-La Roche Ag Conjugated chemical inducers of degradation and methods of use
JP2022513198A (ja) 2018-12-10 2022-02-07 ジェネンテック, インコーポレイテッド Fc含有タンパク質への部位特異的コンジュゲーションのための光架橋性ペプチド
GB201901197D0 (en) 2019-01-29 2019-03-20 Femtogenix Ltd G-A Crosslinking cytotoxic agents
GB2597532A (en) 2020-07-28 2022-02-02 Femtogenix Ltd Cytotoxic compounds
AR128331A1 (es) 2022-01-26 2024-04-17 Genentech Inc Inductores químicos de degradación conjugados con anticuerpos y métodos de estos
AR128330A1 (es) 2022-01-26 2024-04-17 Genentech Inc Inductores químicos de degradación conjugados con anticuerpo y métodos de estos

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999062941A2 (fr) * 1998-06-01 1999-12-09 Urogenesys, Inc. Nouveaux antigenes transmembranaires du type serpentin exprimes dans des cancers humains et utilisation de ces antigenes
WO2000073509A2 (fr) * 1999-06-01 2000-12-07 Incyte Genomics, Inc. Molecules utilisees a des fins diagnostiques et therapeutiques
WO2001005970A2 (fr) * 1999-07-19 2001-01-25 Incyte Genomics, Inc. Proteines associees de liaison gtp

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5599686A (en) * 1994-06-28 1997-02-04 Merck & Co., Inc. Peptides
US5820880A (en) * 1995-06-07 1998-10-13 The United States Of America As Represented By The Secretary Of The Army Liposomal formulation
US6048970A (en) * 1998-05-22 2000-04-11 Incyte Pharmaceuticals, Inc. Prostate growth-associated membrane proteins

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999062941A2 (fr) * 1998-06-01 1999-12-09 Urogenesys, Inc. Nouveaux antigenes transmembranaires du type serpentin exprimes dans des cancers humains et utilisation de ces antigenes
WO2000073509A2 (fr) * 1999-06-01 2000-12-07 Incyte Genomics, Inc. Molecules utilisees a des fins diagnostiques et therapeutiques
WO2001005970A2 (fr) * 1999-07-19 2001-01-25 Incyte Genomics, Inc. Proteines associees de liaison gtp

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL [online] EBI; 10 December 1999 (1999-12-10), EMMANUEL DIAS NETO ET AL: "SHOTGUN SEQUENCING OF THE HUMAN TRANSCRIPTOME WITH ORF EXPRESSED SEQUENCE TAGS", XP002279053, Database accession no. AI908168 *
DATABASE EMBL [online] EBI; 22 February 2000 (2000-02-22), ISOGAI T., OTSUKI T., XP002241852, Database accession no. AK001691 *
DATABASE EMBL [online] EBI; 26 April 1999 (1999-04-26), MAHAIRAS G.G ET AL.: "Sequence-tagged connectors...", Database accession no. AQ456610 *
DIATCHENKO L ET AL: "SUPPRESSION SUBTRACTIVE HYBRIDIZATION: A METHOD FOR GENERATING DIFFERENTIALLY REGULATED OR TISSUE-SPECIFIC CDNA PROBES AND LIBRARIES", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE. WASHINGTON, US, vol. 93, 1 June 1996 (1996-06-01), pages 6025 - 6030, XP002911922, ISSN: 0027-8424 *
MAHAIRAS G G ET AL: "SEQUENCE-TAGGED CONNECTORS: A SEQUENCE APPROACH TO MAPPING AND SCANNING THE HUMAN GENOME", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE. WASHINGTON, US, vol. 96, no. 17, AQ456610, August 1999 (1999-08-01), pages 9739 - 9744, XP002175436, ISSN: 0027-8424 *
WATANABE G ET AL: "PROTEIN KINASE N (PKN) AND PKN-RELATED PROTEIN RHOPHILIN AS TARGETS OF SMALL GTPASE RHO", SCIENCE, AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE,, US, vol. 271, no. 5249, 2 February 1996 (1996-02-02), pages 645 - 648, XP001109460, ISSN: 0036-8075 *

Also Published As

Publication number Publication date
JP2004521602A (ja) 2004-07-22
WO2001072962A2 (fr) 2001-10-04
AU2001249411B2 (en) 2007-02-15
CA2403637A1 (fr) 2001-10-04
WO2001072962A3 (fr) 2002-01-17
EP1268526A2 (fr) 2003-01-02
AU4941101A (en) 2001-10-08
AU2001249411B9 (en) 2001-10-08

Similar Documents

Publication Publication Date Title
AU4941101A (en) Novel prostate-specific or testis-specific nucleic acid molecules, polypeptides,and diagnostic and therapeutic methods
AU3510200A (en) Human dickkopf-related protein and nucleic acid molecules and uses therefor
EP1186615A4 (fr) Proteine et adn de cette proteine
EP1425289A4 (fr) Nouvelles molecules d'acide nucleique et polypeptidiques
AU2001250999A1 (en) Isolated human drug-metabolizing proteins, nucleic acid molecules encoding human drug-metabolizing proteins, and uses thereof
AU2002239256A1 (en) Isolated human drug-metabolizing proteins, nucleic acid molecules encoding human drug-metabolizing proteins, and uses thereof
AU2002213450A1 (en) Isolated human drug-metabolizing proteins, nucleic acid molecules encoding human drug-metabolizing proteins, and uses thereof
EP1293568A4 (fr) Nouvelle proteine et son adn
GB2349150B (en) Expression of DNA or proteins in C. Elegans
NO20020919L (no) Irenprotein, dets fremstilling og anvendelse
EP1383871A4 (fr) Proteines enzymatiques humaines isolees, molecules d'acides nucleiques codant pour ces proteines, et leurs utilisations
AU2001290872A1 (en) Isolated human kinase proteins, nucleic acid molecules and uses thereof
EP1383875A4 (fr) Nadph oxydase humaine isolee, molecules d'acide nucleique codant lesdites proteines et leurs utilisations
AU2003298570A8 (en) Isolated human hepsin/46 proteins, nucleic acid molecules encoding human hepsin/46 proteins, and uses thereof
AU2001271276A1 (en) Isolated human aminotransferase proteins, nucleic acid molecules encoding human aminotransferase proteins, and uses thereof
EP1329504A4 (fr) Acide nucleique d'un nouveau gene humain associe a la kinesine, proteine codees par cet acide nucleique, fragment de peptide de cet acide nucleique et agents anticancereux comprenant cet acide nucleique et similaire
EP1385991A4 (fr) Proteines enzymatiques humaines isolees, molecules d'acide nucleique codant lesdites proteines et utilisations associees
EP1383908A4 (fr) Proteines enzymatiques humaines isolees, molecules d'acides nucleiques codant des proteines enzymatiques humaines et utilisations de celles-ci
EP1383877A4 (fr) Proteines enzymatiques humaines isolees, molecules d'acides nucleiques codant des proteines enzymatiques humaines, et utilisations associees
AU2002229060A1 (en) Isolated human protease proteins, nucleic acid molecules encoding human protease proteins, and uses thereof
EP1379678A4 (fr) Proteines isolees humaines de la protease, molecules d'acide nucleique codant les proteines humaines de la protease et leurs utilisations
EP1383876A4 (fr) Proteines enzymatiques humaines isolees, molecules d'acides nucleiques codant des proteines enzymatiques humaines et leurs utilisations
EP1228085A4 (fr) Molecules d'acides nucleiques et polypeptides gridlock, et methodes diagnostiques et therapeutiques associees
EP1447411A4 (fr) Nouvelle proteine, son adn et son utilisation
AU2002234023A1 (en) Isolated human drug-metabolizing proteins, nucleic acid molecules encoding human drug-metabolizing proteins, and uses thereof

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20021023

AK Designated contracting states

Kind code of ref document: A2

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

AX Request for extension of the european patent

Free format text: AL;LT;LV;MK;RO;SI

RIC1 Information provided on ipc code assigned before grant

Ipc: 7A 61K 38/00 B

Ipc: 7C 07K 14/72 B

Ipc: 7G 01N 33/53 A

RBV Designated contracting states (corrected)

Designated state(s): AT BE CH DE FR GB LI

A4 Supplementary search report drawn up and despatched

Effective date: 20040727

17Q First examination report despatched

Effective date: 20070503

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20071114