EP1263389B1 - Recipient pour substances pateuses ou liquides et ensembles de tels recipients - Google Patents
Recipient pour substances pateuses ou liquides et ensembles de tels recipients Download PDFInfo
- Publication number
- EP1263389B1 EP1263389B1 EP01923650A EP01923650A EP1263389B1 EP 1263389 B1 EP1263389 B1 EP 1263389B1 EP 01923650 A EP01923650 A EP 01923650A EP 01923650 A EP01923650 A EP 01923650A EP 1263389 B1 EP1263389 B1 EP 1263389B1
- Authority
- EP
- European Patent Office
- Prior art keywords
- containers
- container
- semi
- necks
- dose
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Images
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D75/00—Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes, or webs of flexible sheet material, e.g. in folded wrappers
- B65D75/52—Details
- B65D75/58—Opening or contents-removing devices added or incorporated during package manufacture
- B65D75/5805—Opening or contents-removing devices added or incorporated during package manufacture for tearing a side strip parallel and next to the edge, e.g. by means of a line of weakness
- B65D75/5811—Opening or contents-removing devices added or incorporated during package manufacture for tearing a side strip parallel and next to the edge, e.g. by means of a line of weakness and defining, after tearing, a small dispensing spout, a small orifice or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
- A61J1/06—Ampoules or carpules
- A61J1/067—Flexible ampoules, the contents of which are expelled by squeezing
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D1/00—Containers having bodies formed in one piece, e.g. by casting metallic material, by moulding plastics, by blowing vitreous material, by throwing ceramic material, by moulding pulped fibrous material, by deep-drawing operations performed on sheet material
- B65D1/09—Ampoules
- B65D1/095—Ampoules made of flexible material
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D75/00—Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes, or webs of flexible sheet material, e.g. in folded wrappers
- B65D75/28—Articles or materials wholly enclosed in composite wrappers, i.e. wrappers formed by associating or interconnecting two or more sheets or blanks
- B65D75/30—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding
- B65D75/32—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents
- B65D75/321—Both sheets being recessed
- B65D75/323—Both sheets being recessed and forming several compartments
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D75/00—Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes, or webs of flexible sheet material, e.g. in folded wrappers
- B65D75/28—Articles or materials wholly enclosed in composite wrappers, i.e. wrappers formed by associating or interconnecting two or more sheets or blanks
- B65D75/30—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding
- B65D75/32—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents
- B65D75/325—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents one sheet being recessed, and the other being a flat not- rigid sheet, e.g. puncturable or peelable foil
- B65D75/327—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents one sheet being recessed, and the other being a flat not- rigid sheet, e.g. puncturable or peelable foil and forming several compartments
Definitions
- the object of this invention is a differentiated dosage container, particularly for liquid or pasty substances but also usable for powdered substances, suspensions, liposomial preparations for pharmaceuticals, diagnostics, cosmetics and the like.
- the invention also concerns sets of these containers.
- US patent 3221939 dated 1962 describes such a container for small volumes and illustrates an attempt to make a set or strip of these containers. It also illustrates the possibility of providing the containers with closures able to dispense the contents in several doses.
- Patent US-4512475 dated 1983 describes a set of containers pressed in one piece with a closure plug, which, once removed from the container can be used to close it again.
- the plug has a cylindrical cap, which inserts into the neck of the container and a tubular shell, which fits around the neck.
- EP-0326529 dated 1989 describes a series of details and improvements aimed at facilitating the separation of the containers from the sets and to improve the rigidity and the machinability of the sets.
- WO 98/01348 describes a set of containers provided with plugs for re-closing, so as to allow a fractionated consumption of the product.
- the various containers of the set are joined between themselves by means of easily separated elements, opportunely inclined, so as to increase the rigidity of the set and thus reduce problems on the production line.
- WO-A-95/11176 discloses a necked container including a drinking straw.
- the container which is in the form of a sachet, is divided by a partition wall into two compartments, for containing different foods.
- the partition wall can be perforated so that the two compartments of the sachet can be split apart.
- DE 19 627 243 discloses a container comprising two semi-containers provided with respective cavities and necks arranged side by side. Each semi-container is defined by a flat wall and a shaped wall on which the cavities and necks are formed.
- the container is provided with opening means comprising a horizontal pre-cut line extending across the necks in order to allow the semi-containers to be opened.
- antimicrobial activity e.g. benzyl alcohol, paraben, sodium benzoate, benzalkonium chloride
- anti-oxidant activity e.g. butyl-hydroxytoluene, butyl-hydroxyanisole, propyl gallate, sulphites
- the object of the invention is that of resolving the above mentioned problem, by providing a single dose container that is able to dispense even fractions of its content guaranteeing the microbiological quality of the product.
- the container according to the invention has two separate half doses disposed in two respective semi-containers, with the necks close together and parallel.
- the top of the container presents two different pre-cut lines, one horizontal involving the necks of both semi-containers and one oblique involving the neck of a sole semi-container.
- the opening along the horizontal pre-cut the entire dose is dispensed, that is the contents of the two semi-containers, whereas in making the opening along the oblique pre-cut, the contents of a sole semi-container can be dispensed.
- the remaining half dose does not come into contact with the operator or with the surroundings, remaining sealed in its respective housing and in consequence maintaining the integrity and microbiological quality of the product, even in the absence of preservatives.
- the containers according to the invention can be made in sets with thermoforming techniques, injection moulding, extrusion and blow moulding, from which sets and single containers or semi-containers are detached from time to time.
- the containers of the invention are prepared by a process comprising the following steps:
- the containers or sets of containers can be suitably packed in aluminium or aluminium/plastic envelopes to protect them from external contamination and to prevent the possible evaporation of solvents.
- a container or single dose "phialoid” has been indicated in its whole by reference number 1 and consists of two semi-containers or “semi-phialoids” each containing a half dose and with their necks 3, close together and parallel.
- the bodies 4 of the semi-containers 2 have a conveniently rounded form with respect to a media plan, as can be seen from Figure 2.
- the semi-containers 2 that are contained in a sheet of plastic material, such as polyethylene, polypropylene, polystyrene, PVC, PVDC or similar, from which they are obtained by thermoforming or other known moulding and pressing techniques.
- the sheet 6 is in practice a substantially rectangular plate that contains the bodies 4 of the semi-containers 2, presenting a narrowing 7 in the upper part, in correspondence with the necks 3 of the semi-containers, and an upper fin 8 that contains the tops of the said necks 3.
- both of the semi-containers 2 are opened and the entire dose can be dispensed from the container.
- a half of the fin 8 is removed causing the opening of the neck 3 of a sole semi-container 2 and then a sole half dose from container 1 can be used.
- the containers 1 can be produced in sets 20, as shown in Figure 3, comprising a plurality of these containers 1, joined together by their breakable joints 21 which only allow separation at the moment of use.
- each container 1 can vary from 1 ml to 30 ml, for which the volume of each semi-container 2 will vary from 0.5 ml to 15 ml.
- a vertical pre-cut line 110 is provided between the two semi-containers 2 in the plate 6; this allows the separation of the two semi-containers or alternatively to adopt the "book-like" folding of these semi-containers without separation (see Figure 7 in particular).
- each semi-container 2 has a rounded form which is developed on one side only of the plate 6, while the other side of the plate remains substantially flat (see Figure 5 in particular), so that there are no obstacles to the above mentioned "book-like” folding.
- the form of the semi-containers 2 does not differ from that of the first embodiment, and a horizontal pre-cut line 109, is provided, which concerns the top of the necks 3 of the semi-containers 2, which in the attached Figure, has been drawn in a slightly higher position than the corresponding pre-cut line 9 of the first embodiment but it is evident that the pre-cut line 109 can be positioned at the same height as the corresponding pre-cut line 9.
- Figure 8 shows a set 20 of containers according to the Figures from 4 to 7.
Landscapes
- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Composite Materials (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Ceramic Engineering (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- Packages (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Cosmetics (AREA)
- Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
- Closures For Containers (AREA)
Claims (5)
- Récipient pour substances liquides et pâteuses, poudres, suspensions ou préparations liposomiales à usage pharmaceutique, diagnostique, cosmétique et analogue inclus dans une plaque (6) de matière plastique, ledit récipient (1) comprenant deux demi-récipients (2) dont les corps (4) et les cols (3) sont raccordés ensemble et sont parallèles, deux prédécoupes (9, 10) étant fournies en correspondance avec lesdits cols (3), pour permettre l'ouverture sélective d'un ou des deux dits demi-récipients (2) et par conséquent, l'administration de la dose entière ou d'une demi-dose du produit, caractérisé en ce que lesdites deux prédécoupes (9, 10) comprennent une ligne de prédécoupe horizontale (9) qui concerne les cols (3) des deux demi-récipients (2), de telle sorte que son ouverture permette l'administration de la dose entière du récipient (1) et une ligne de prédécoupe oblique (10) qui concerne le haut du col (3) de seulement l'un desdits demi-récipients (2), de telle sorte que son ouverture permette l'administration d'une demi-dose du produit du récipient (1).
- Récipient selon la revendication 1, caractérisé en ce que lesdits corps (4) des demi-récipients (2) ont une double forme arrondie, des deux côtés de ladite plaque (6).
- Récipient selon la revendication 1, caractérisé en ce que lesdits corps (4) des demi-récipients (2) ont une forme arrondie seulement d'un côté de ladite plaque (6), de telle sorte que l'autre côté de la plaque (6) soit sensiblement plat.
- Récipient selon l'une quelconque des revendications précédentes, caractérisé en ce qu'il est raccordé par une ligne de raccordement cassable (21) à d'autres récipients identiques pour former un ensemble (20) de récipients.
- Récipient selon l'une quelconque des revendications précédentes, caractérisé en ce qu'il est inclus dans une enveloppe d'aluminium ou de matière plastique ou d'une combinaison des deux.
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP01923650A EP1263389B1 (fr) | 2000-03-14 | 2001-03-08 | Recipient pour substances pateuses ou liquides et ensembles de tels recipients |
SI200130103T SI1263389T1 (en) | 2000-03-14 | 2001-03-08 | Container for liquid or pasty substances and container sets thereof |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP00830190 | 2000-03-14 | ||
EP00830190A EP1133969A1 (fr) | 2000-03-14 | 2000-03-14 | Ampoule pour substances liquides ou pâteuses en doses différenciées et ensembles de ce type d'ampoules |
EP01923650A EP1263389B1 (fr) | 2000-03-14 | 2001-03-08 | Recipient pour substances pateuses ou liquides et ensembles de tels recipients |
PCT/EP2001/002590 WO2001068030A1 (fr) | 2000-03-14 | 2001-03-08 | Recipient pour substances pateuses ou liquides a doses differentiees et ensembles de recipients a cet effet |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1263389A1 EP1263389A1 (fr) | 2002-12-11 |
EP1263389B1 true EP1263389B1 (fr) | 2004-05-19 |
Family
ID=8175236
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP00830190A Withdrawn EP1133969A1 (fr) | 2000-03-14 | 2000-03-14 | Ampoule pour substances liquides ou pâteuses en doses différenciées et ensembles de ce type d'ampoules |
EP01923650A Expired - Lifetime EP1263389B1 (fr) | 2000-03-14 | 2001-03-08 | Recipient pour substances pateuses ou liquides et ensembles de tels recipients |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP00830190A Withdrawn EP1133969A1 (fr) | 2000-03-14 | 2000-03-14 | Ampoule pour substances liquides ou pâteuses en doses différenciées et ensembles de ce type d'ampoules |
Country Status (9)
Country | Link |
---|---|
EP (2) | EP1133969A1 (fr) |
AT (1) | ATE266994T1 (fr) |
AU (1) | AU2001250370A1 (fr) |
DE (1) | DE60103377T2 (fr) |
DK (1) | DK1263389T3 (fr) |
ES (1) | ES2220761T3 (fr) |
PT (1) | PT1263389E (fr) |
SI (1) | SI1263389T1 (fr) |
WO (1) | WO2001068030A1 (fr) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2024068523A1 (fr) | 2022-09-30 | 2024-04-04 | Boehringer Ingelheim Vetmedica Gmbh | Emballage d'administration, appareil de production et procédé de production |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6457612B1 (en) * | 2001-10-12 | 2002-10-01 | Amphastar Pharmaceuticals Inc. | Sealable and manipulable pre-filled disposable pipette |
GB2407312A (en) * | 2003-10-23 | 2005-04-27 | Maureen Linda Blogg | Divided or separable container for liquid medicines |
GB0513581D0 (en) | 2005-07-01 | 2005-08-10 | Norton Healthcare Ltd | Container |
FR2894942A1 (fr) * | 2005-12-15 | 2007-06-22 | Ronith Stemmer | Dispositif de conditionnement et de distribution de produits dentaires |
US20090114677A1 (en) * | 2007-11-05 | 2009-05-07 | Geoffrey Catherwood Stuart | Dual Receptacle Symmetrical Package for Liquids |
FR2945797B1 (fr) | 2009-05-20 | 2015-11-06 | Virbac Sa | Conditionnement alimentaire,pharmaceutique ou veterinaire de securite et son procede de fabrication |
DE102010031734A1 (de) | 2010-07-21 | 2012-01-26 | Multivac Sepp Haggenmüller Gmbh & Co. Kg | Verpackung für ein flüssiges, pulvriges oder pastöses Produkt |
CN109573324A (zh) * | 2019-01-16 | 2019-04-05 | 叶卫东 | 一次性补充液包装瓶 |
WO2020180202A1 (fr) * | 2019-03-01 | 2020-09-10 | Николай Валерьевич ХОХЛОВ | Composition à base de nanoparticules de dioxyde de cérium et de polysaccharides d'algues brunes pour traiter les blessures |
US11548710B2 (en) * | 2019-04-15 | 2023-01-10 | Contract Pharmaceuticals Limited | Break-open single-dose packages |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3221939A (en) | 1962-01-08 | 1965-12-07 | Barnes Hind International Inc | Disposable dispensers |
GB1275903A (en) * | 1968-08-27 | 1972-06-01 | Smith & Nephew | Dispenser |
US3913734A (en) * | 1972-08-03 | 1975-10-21 | Pharmacare Inc | Package assembly |
IT8253314V0 (it) | 1983-11-04 | 1982-05-21 | Farmigea Spa | Minicontenitori monodose o plurido se di prodotti farmaceutici |
DE68904082T2 (de) | 1988-01-28 | 1993-07-29 | Lameplast Srl | Flaeschchenkette fuer pharmazeutische, kosmetische und andere produkte. |
DE3833036C2 (de) * | 1988-09-29 | 1998-03-19 | Bernd Hansen | Doppelkammerbehälter |
GB9321750D0 (en) * | 1993-10-21 | 1993-12-15 | Cambridge Consultants | Improvements in or relating to packaging |
IT1284115B1 (it) | 1996-07-05 | 1998-05-08 | Chiesi Farma Spa | Stecca di contenitori per sostanze liquide o pastose |
DE19627243A1 (de) * | 1996-07-08 | 1998-01-15 | Hassia Verpackung Ag | Verpackung |
-
2000
- 2000-03-14 EP EP00830190A patent/EP1133969A1/fr not_active Withdrawn
-
2001
- 2001-03-08 AT AT01923650T patent/ATE266994T1/de active IP Right Revival
- 2001-03-08 ES ES01923650T patent/ES2220761T3/es not_active Expired - Lifetime
- 2001-03-08 DK DK01923650T patent/DK1263389T3/da active
- 2001-03-08 PT PT01923650T patent/PT1263389E/pt unknown
- 2001-03-08 AU AU2001250370A patent/AU2001250370A1/en not_active Abandoned
- 2001-03-08 EP EP01923650A patent/EP1263389B1/fr not_active Expired - Lifetime
- 2001-03-08 WO PCT/EP2001/002590 patent/WO2001068030A1/fr active IP Right Grant
- 2001-03-08 SI SI200130103T patent/SI1263389T1/xx unknown
- 2001-03-08 DE DE60103377T patent/DE60103377T2/de not_active Expired - Lifetime
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2024068523A1 (fr) | 2022-09-30 | 2024-04-04 | Boehringer Ingelheim Vetmedica Gmbh | Emballage d'administration, appareil de production et procédé de production |
Also Published As
Publication number | Publication date |
---|---|
SI1263389T1 (en) | 2004-08-31 |
ES2220761T3 (es) | 2004-12-16 |
AU2001250370A1 (en) | 2001-09-24 |
EP1263389A1 (fr) | 2002-12-11 |
DE60103377D1 (de) | 2004-06-24 |
PT1263389E (pt) | 2004-09-30 |
DE60103377T2 (de) | 2004-09-16 |
WO2001068030A1 (fr) | 2001-09-20 |
EP1133969A1 (fr) | 2001-09-19 |
ATE266994T1 (de) | 2004-06-15 |
DK1263389T3 (da) | 2004-09-27 |
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