Classifications

• • B—PERFORMING OPERATIONS; TRANSPORTING
  • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
  • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
  • B65D75/00—Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes, or webs of flexible sheet material, e.g. in folded wrappers
  • B65D75/52—Details
  • B65D75/58—Opening or contents-removing devices added or incorporated during package manufacture
  • B65D75/5805—Opening or contents-removing devices added or incorporated during package manufacture for tearing a side strip parallel and next to the edge, e.g. by means of a line of weakness
  • B65D75/5811—Opening or contents-removing devices added or incorporated during package manufacture for tearing a side strip parallel and next to the edge, e.g. by means of a line of weakness and defining, after tearing, a small dispensing spout, a small orifice or the like
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
  • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
  • A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
  • A61J1/06—Ampoules or carpules
  • A61J1/067—Flexible ampoules, the contents of which are expelled by squeezing
• • B—PERFORMING OPERATIONS; TRANSPORTING
  • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
  • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
  • B65D1/00—Containers having bodies formed in one piece, e.g. by casting metallic material, by moulding plastics, by blowing vitreous material, by throwing ceramic material, by moulding pulped fibrous material, by deep-drawing operations performed on sheet material
  • B65D1/09—Ampoules
  • B65D1/095—Ampoules made of flexible material
• • B—PERFORMING OPERATIONS; TRANSPORTING
  • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
  • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
  • B65D75/00—Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes, or webs of flexible sheet material, e.g. in folded wrappers
  • B65D75/28—Articles or materials wholly enclosed in composite wrappers, i.e. wrappers formed by associating or interconnecting two or more sheets or blanks
  • B65D75/30—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding
  • B65D75/32—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents
  • B65D75/321—Both sheets being recessed
  • B65D75/323—Both sheets being recessed and forming several compartments
• • B—PERFORMING OPERATIONS; TRANSPORTING
  • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
  • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
  • B65D75/00—Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes, or webs of flexible sheet material, e.g. in folded wrappers
  • B65D75/28—Articles or materials wholly enclosed in composite wrappers, i.e. wrappers formed by associating or interconnecting two or more sheets or blanks
  • B65D75/30—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding
  • B65D75/32—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents
  • B65D75/325—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents one sheet being recessed, and the other being a flat not- rigid sheet, e.g. puncturable or peelable foil
  • B65D75/327—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents one sheet being recessed, and the other being a flat not- rigid sheet, e.g. puncturable or peelable foil and forming several compartments

Definitions

• the object of this invention is a differentiated dosage container , particularly for liquid or pasty substances but also usable for powdered substances, suspensions, liposomial preparations for pharmaceuticals, diagnostics, cosmetics and the like.
• the invention also concerns sets of these containers.
• US patent 3221939 dated 1962 describes such a container for small volumes and illustrates an attempt to make a set or strip of these containers. It also illustrates the possibility of providing the containers with closures able to dispense the contents in several doses.
• Patent US-4512475 dated 1983 describes a set of containers pressed in one piece with a closure plug, which, once removed from the container can be used to close it again.
• the plug has a cylindrical cap, which inserts into the neck of the container and a tubular shell, which fits around the neck.
• EP-0326529 dated 1989 describes a series of details and improvements aimed et facilitating the separation of the containers from the sets and to improve the rigidity and the machinability of the sets.
• WO 98/01348 describes a set of containers provided with plugs for re-closing, so as to allow a fractionated consumption of the product.
• the various containers of the set are joined between themselves by means of easily separated elements, opportunely inclined, so as to increase the rigidity of the set and thus reduce problems on the production line.
• the problem of being able to use the contents of a single container in more than one part has been resolved by means of a plug which is removed at the moment of opening the container and can then be used to close it again and conserve any second dose of product.
• antimicrobial activity e.g. benzyl alcohol, paraben, sodium benzoate, benzalkonium chloride
• anti-oxidant activity e.g. butyl- hydroxytoluene, butyl-hydroxyanisole, propyl gallate, sulphites
• the object of the invention is that of resolving the above mentioned problem, by providing a single dose container that is able to dispense even fractions of its content guaranteeing the microbiological quality of the product. This object is achieved, according to the invention, by the features of the enclosed independent claim 1.
• the container according to the invention has two separate half doses disposed in two respective semi-containers, with the necks close together and parallel.
• the top of the container presents two different pre-cut lines, one horizontal involving the necks of both semi-containers and one oblique involving the neck of a sole semi- container.
• the opening along the horizontal pre-cut the entire dose is dispensed, that is the contents of the two semi-containers, whereas in making the opening along the oblique pre-cut, the contents of a sole semi-container can be dispensed.
• the remaining half dose does not come into contact with the operator or with the surroundings, remaining sealed in its respective housing and in consequence maintaining the integrity and microbiological quality of the product, even in the absence of preservatives.
• the container still presents two separate half doses disposed in semi-containers, with the necks close together and parallel.
• a vertical pre-cut is made between the two semi- containers, which allows their separation, but also their "book-like” folding without separation.
• There is a horizontal pre-cut at the top of the container that allows: the dispensing of the entire dose in opening the container after having made a "book-like” fold, the dispensing of a half dose in opening the single semi-container after having separated it from the other half using the vertical pre-cut.
• the remaining half dose does not come into contact with the operator or with the surroundings and in consequence it maintains the integrity and microbiological quality of the product, even in the absence of preservatives.
• This second method as distinct from the first, allows the reduction, at the moment of use, of the encumbrance of the top part (neck), both in the case of complete opening and in the case of a half dose, this facilitates the transfer of the "phialoid " contents in restricted spaces, as in the case of ampoules for aerosol therapy.
• the containers according to the invention can be made in sets with thermoforming techniques, injection moulding, extrusion and blow moulding, from which sets and single containers or semi-containers are detached from time to time. More precisely, the containers of the invention are prepared by a process comprising the following steps: thermoforming of the cavity, leaving a channel open for filling; filling of the cavity with the desired quantity of product; welding and closing of the filling channel; - cutting and removal of the flash according to the design of the container; cutting loose of individual containers or cutting off strips of the number of containers required;
• containers or sets of containers can be suitably packed in aluminium or aluminium/plastic envelopes to protect them from external contamination and to prevent the possible evaporation of solvents.
• Figure 1 is a plan view of a container according to a first embodiment of the invention
• Figure 2 is a lateral profile view of the container in Figure 1 ;
• Figure 3 is a plan view of the set of containers in Figure 1 ;
• Figure 4 is a plan view of a container according to a second embodiment of the invention;
• Figure 5 is a lateral profile view, taken from the right-hand side of Figure
• Figure 6 is a plan view showing the two semi-containers of Figure 4 with a "book-like" fold, the plan view of a sole semi-container being substantially the same;
• Figure 7 is a lateral profile view of two semi-containers with "book-like” fold, taken from the right-hand side of Figure 6;
• Figure 8 is a plan view of a set of containers according to figure 4.
• a container or single dose "phialoid” has been indicated in its whole by reference number 1 and consists of two semi-containers or “semi- phial oids” each containing a half dose and with their necks 3, close together and parallel.
• the bodies 4 of the semi-containers 2 have a conveniently rounded form with respect to a media plan, as can be seen from Figure 2.
• the semi-containers 2 that are contained in a sheet of plastic material, such as polyethylene, polypropylene, polystyrene, PVC, PVDC or similar, from which they are obtained by thermoforming or other known moulding and pressing techniques.
• the sheet 6 is in practice a substantially rectangular plate that contains the bodies 4 of the semi- containers 2, presenting a narrowing 7 in the upper part, in correspondence with the necks 3 of the semi-containers, and an upper fin 8 that contains the tops of the said necks 3.
• the container 1 there are two different pre-cut lines, one horizontal 9, disposed immediately beneath the said upper fin 8 of the plate 6, which concerns the necks 3 of both semi-containers 2, and one oblique 10 disposed on the said fin 8 and concerning the top of the neck 3 of a sole semi-container 2.
• both of the semi-containers 2 are opened and the entire dose can be dispensed from the container.
• a half of the fin 8 is removed causing the opening of the neck 3 of a sole semi-container 2 and then a sole half dose from container 1 can be used.
• the containers 1 can be produced in sets 20, as shown in Figure 3, comprising a plurality of these containers 1, joined together by their breakable joints 21 which only allow separation at the moment of use.
• each container 1 can vary from 1 ml to 30 ml, for which the volume of each semi-container 2 will vary from 0.5 ml to 15 ml.
• the second embodiment of the invention will now be described, using the same reference numbers as for the first embodiment, sometimes increased by 100, to distinguish parts that are equal or corresponding. Substantially, according to this embodiment, a vertical pre-cut line
• each semi-container 2 has a rounded form which is developed on one side only of the plate 6, while the other side of the plate remains substantially flat (see Figure 5 in particular), so that there are no obstacles to the above mentioned "book-like" folding.
• the form of the semi- containers 2 does not differ from that of the first embodiment, and a horizontal pre-cut line 109, is provided, which concerns the top of the necks 3 of the semi-containers 2, which in the attached Figure, has been drawn in a slightly higher position than the corresponding pre-cut line 9 of the first embodiment but it is evident that the pre-cut line 109 can be positioned at the same height as the corresponding pre-cut line 9.
• Figure 8 shows a set 20 of containers according to the Figures from 4 to 7.

Landscapes

• Engineering & Computer Science (AREA)
• Mechanical Engineering (AREA)
• Health & Medical Sciences (AREA)
• Chemical & Material Sciences (AREA)
• Composite Materials (AREA)
• Pharmacology & Pharmacy (AREA)
• Animal Behavior & Ethology (AREA)
• General Health & Medical Sciences (AREA)
• Public Health (AREA)
• Veterinary Medicine (AREA)
• Ceramic Engineering (AREA)
• Life Sciences & Earth Sciences (AREA)
• Hematology (AREA)
• Packages (AREA)
• Medical Preparation Storing Or Oral Administration Devices (AREA)
• Cosmetics (AREA)
• Closures For Containers (AREA)
• Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)

Priority Applications (2)

Applications Claiming Priority (4)

Publications (2)

Family

ID=8175236

Family Applications (2)

Family Applications Before (1)

Country Status (9)

Families Citing this family (11)

Family Cites Families (9)

• 2000
  • 2000-03-14 EP EP00830190A patent/EP1133969A1/fr not_active Withdrawn
• 2001
  • 2001-03-08 ES ES01923650T patent/ES2220761T3/es not_active Expired - Lifetime
  • 2001-03-08 DK DK01923650T patent/DK1263389T3/da active
  • 2001-03-08 SI SI200130103T patent/SI1263389T1/xx unknown
  • 2001-03-08 PT PT01923650T patent/PT1263389E/pt unknown
  • 2001-03-08 EP EP01923650A patent/EP1263389B1/fr not_active Expired - Lifetime
  • 2001-03-08 AT AT01923650T patent/ATE266994T1/de active IP Right Revival
  • 2001-03-08 AU AU2001250370A patent/AU2001250370A1/en not_active Abandoned
  • 2001-03-08 WO PCT/EP2001/002590 patent/WO2001068030A1/fr active IP Right Grant
  • 2001-03-08 DE DE60103377T patent/DE60103377T2/de not_active Expired - Lifetime

Non-Patent Citations (1)

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