EP1259227A1 - Procede de production de formes galeniques pharmaceutiques - Google Patents

Procede de production de formes galeniques pharmaceutiques

Info

Publication number
EP1259227A1
EP1259227A1 EP01907526A EP01907526A EP1259227A1 EP 1259227 A1 EP1259227 A1 EP 1259227A1 EP 01907526 A EP01907526 A EP 01907526A EP 01907526 A EP01907526 A EP 01907526A EP 1259227 A1 EP1259227 A1 EP 1259227A1
Authority
EP
European Patent Office
Prior art keywords
dried
mannitol
spray
granules
cerivastatin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP01907526A
Other languages
German (de)
English (en)
Inventor
Tobias Laich
Carola PÖRTNER
Jan-Olav Henck
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Bayer Healthcare AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG, Bayer Healthcare AG filed Critical Bayer AG
Publication of EP1259227A1 publication Critical patent/EP1259227A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules

Abstract

L'invention concerne un procédé permettant de produire des granulés à l'aide de D-mannitol séché par pulvérisation, ainsi que des formes galéniques pharmaceutiques à base desdits granulés. L'invention concerne en outre des granulés pouvant être obtenus d'après ledit procédé, ainsi que des formes galéniques pharmaceutiques contenant des statines, en particulier de la cérivastatine, et pouvant être produites à partir desdits granulés.
EP01907526A 2000-02-24 2001-02-13 Procede de production de formes galeniques pharmaceutiques Withdrawn EP1259227A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10008506 2000-02-24
DE2000108506 DE10008506A1 (de) 2000-02-24 2000-02-24 Verfahren zur Herstellung von pharmazeutischen Darreichungsformen
PCT/EP2001/001565 WO2001062230A1 (fr) 2000-02-24 2001-02-13 Procede de production de formes galeniques pharmaceutiques

Publications (1)

Publication Number Publication Date
EP1259227A1 true EP1259227A1 (fr) 2002-11-27

Family

ID=7632144

Family Applications (1)

Application Number Title Priority Date Filing Date
EP01907526A Withdrawn EP1259227A1 (fr) 2000-02-24 2001-02-13 Procede de production de formes galeniques pharmaceutiques

Country Status (4)

Country Link
EP (1) EP1259227A1 (fr)
AU (1) AU3547001A (fr)
DE (1) DE10008506A1 (fr)
WO (1) WO2001062230A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2379887C (fr) * 2002-04-09 2004-01-20 Bernard Charles Sherman Comprimes stables contenant de la simvastatine
DE102007052070A1 (de) 2007-10-30 2009-05-07 Tiefenbacher Pharmachemikalien Alfred E. Tiefenbacher Gmbh & Co. Kg Candesartancilexetil
EP2138165A1 (fr) 2008-06-27 2009-12-30 KRKA, tovarna zdravil, d.d., Novo mesto Composition pharmaceutique comportant de la statine
RU2606592C1 (ru) * 2015-10-07 2017-01-10 Открытое Акционерное Общество "Татхимфармпрепараты" Фармацевтическая композиция, содержащая кальциевую соль розувастатина (варианты)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3145146A (en) * 1961-10-31 1964-08-18 Warner Lambert Pharmaceutical Modified mannitol for pharmaceutical tablets
US5350584A (en) * 1992-06-26 1994-09-27 Merck & Co., Inc. Spheronization process using charged resins
ID16566A (id) * 1996-04-16 1997-10-16 Takeda Chemical Industries Ltd D-manitol dan pembuatannya

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See references of WO0162230A1 *

Also Published As

Publication number Publication date
DE10008506A1 (de) 2001-09-13
AU3547001A (en) 2001-09-03
WO2001062230A1 (fr) 2001-08-30

Similar Documents

Publication Publication Date Title
DE10038110B4 (de) Pharmazeutische Zusammensetzungen
AT401870B (de) Stabilisiertes pharmazeutisches mittel, enthaltend einen hmg-coa-reduktase-inhibitor wirkstoff
RU2142790C1 (ru) Фармацевтическая композиция, стабилизированная основным агентом
EP2229938B1 (fr) Compositions d'ézétimibe
DE69915478T2 (de) Geschmacksmaskierung mittels croscarmellose
EP1501546B1 (fr) Formulation pharmaceutique stable contenant une statine combinee avec un inhibiteur de l'ace
KR20070007129A (ko) 안정성이 향상된 고형 제제 및 그 제조 방법
ZA200309289B (en) Oxcarbazepine dosage forms.
CN102143738A (zh) 药物固体制剂
EP1259227A1 (fr) Procede de production de formes galeniques pharmaceutiques
US8062664B2 (en) Process for preparing formulations of lipid-regulating drugs
US7642286B2 (en) Stable pharmaceutical compositions containing pravastatin
US20030031720A1 (en) Method for producing pharmaceutical dosage forms
DE102005049293A1 (de) Kombinationspräparate von Salzen oder o-Acetylsalicylsäure
DE10152351A1 (de) Feste Arzneimittelformulierung für ein Piperazinharnstoffderivat
EP1818050A1 (fr) Compositions pharmaceutiques stables comprenants un inhibiteur de la HMG-CoA réductase
DE4245089B4 (de) Stabilisiertes pharmazeutisches Mittel, enthaltend einen HMG-CoA-Reduktase-Inhibitor als Wirkstoff
EP1825848A2 (fr) Compositions pharmaceutiques stables comprenant un inhibiteur de la HMG-CoA réductase
CA2531097C (fr) Procede de preparation de produits formules de medicaments de regulation du metabolisme lipidique
CN114903862A (zh) 一种多廿烷醇阿托伐他汀钙复方制剂及其制备方法
US20060177512A1 (en) Process for preparing formulations of lipid-regulating drugs
AU2002314915A1 (en) Stable pharmaceutical compositions containing pravastatin
MXPA00007656A (en) Pharmaceutical compositions

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20020924

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

AX Request for extension of the european patent

Free format text: AL;LT;LV;MK;RO;SI

RIN1 Information on inventor provided before grant (corrected)

Inventor name: HENCK, JAN-OLAV

Inventor name: LAICH, TOBIAS

Inventor name: POERTNER, CAROLA

RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: BAYER HEALTHCARE AG

RBV Designated contracting states (corrected)

Designated state(s): DE ES FR GB IT

17Q First examination report despatched

Effective date: 20050321

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20050802