EP1096999B1 - Plaque pour l'analyse biologique et la conservation d'echantillons biologiques - Google Patents
Plaque pour l'analyse biologique et la conservation d'echantillons biologiques Download PDFInfo
- Publication number
- EP1096999B1 EP1096999B1 EP99929483A EP99929483A EP1096999B1 EP 1096999 B1 EP1096999 B1 EP 1096999B1 EP 99929483 A EP99929483 A EP 99929483A EP 99929483 A EP99929483 A EP 99929483A EP 1096999 B1 EP1096999 B1 EP 1096999B1
- Authority
- EP
- European Patent Office
- Prior art keywords
- plate according
- buckets
- plate
- bucket
- surrounded
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000004458 analytical method Methods 0.000 title description 4
- 239000012472 biological sample Substances 0.000 title description 3
- 238000004321 preservation Methods 0.000 title description 2
- 239000004033 plastic Substances 0.000 claims abstract description 9
- 238000005497 microtitration Methods 0.000 claims abstract description 5
- 230000000295 complement effect Effects 0.000 claims abstract description 3
- 239000007788 liquid Substances 0.000 claims abstract 2
- 239000000463 material Substances 0.000 claims description 8
- 230000003313 weakening effect Effects 0.000 claims description 6
- 230000002787 reinforcement Effects 0.000 claims description 3
- 230000002238 attenuated effect Effects 0.000 abstract 2
- 230000002093 peripheral effect Effects 0.000 description 4
- 239000004793 Polystyrene Substances 0.000 description 2
- 238000000465 moulding Methods 0.000 description 2
- 229920002223 polystyrene Polymers 0.000 description 2
- 238000000926 separation method Methods 0.000 description 2
- 230000001464 adherent effect Effects 0.000 description 1
- 238000005842 biochemical reaction Methods 0.000 description 1
- 239000013060 biological fluid Substances 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 238000004113 cell culture Methods 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 239000002991 molded plastic Substances 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 238000004381 surface treatment Methods 0.000 description 1
- 239000012780 transparent material Substances 0.000 description 1
Images
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
- B01L3/5085—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/54—Labware with identification means
- B01L3/545—Labware with identification means for laboratory containers
- B01L3/5453—Labware with identification means for laboratory containers for test tubes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D2203/00—Decoration means, markings, information elements, contents indicators
- B65D2203/06—Arrangements on packages concerning bar-codes
Definitions
- the present invention relates to the field of biological analysis and preservation of samples organic.
- microtiter plates It is known in the state of the art to use plates, called microtiter plates. These Plates generally have a multitude of wells organized according to a two-dimensional network. Each of these well may contain a biological sample.
- the European patent EP611597 describes a micro titration unit comprising at least one container that is made of a transparent material and that has an orifice for receiving a mixture biological test reaction.
- European Patent EP92140 discloses a plate of micro test comprising a frame and a central portion provided with containers, characterized in that the edge upper frame of the micro test plate is separated from the central part, with the exception of a few points of connected by a continuous opening, in that it includes crosspieces perpendicular to its surface and recesses, preferably small notches, arranged vis-à-vis between the sleepers on the lower support edge of the frame.
- European Patent EP84102 discloses a plate of micro titration for the diagnosis of the blood group, consisting of a flat bottom plate made of polystyrene rigid and transparent, which is provided with a large number of small buckets, characterized in that the bottom of the buckets has adherent dry layers made for the essence of pure antisera, and in that the cups are consist of a polystyrene suitable for protein binding, radiation sterilized, such as surface treatment for cell cultures.
- the object of the invention is to propose a plate allowing a separation of the wells as and when measurement of needs, thus avoiding the transfer of plates to the analysis equipment.
- a plate also allows the conservation of any type biological samples in the form of a single plate, and the use of a well when needed.
- the invention relates more particularly to a plate intended especially for micro titration, presenting a plurality of buckets for receiving samples of a biological fluid characterized in that the buckets are detachable.
- the plate according to the invention consists of a molded plastic part having a plurality of hollow protuberances constituting the buckets, each of these protuberances being surrounded by a breakable line.
- the buckets are extended, above the upper surface of the plate, by a sleeve adapted to cooperate with a tool allowing rotate to produce breakage of the bucket.
- the buckets are surrounded by a rupture zone with lines of weakness.
- the buckets are surrounded by a zone presenting alternately radial reinforcements extending the bucket, and lights of a section at less equal to that of radial reinforcements.
- the buckets are surrounded by a rupture zone with semicircular shoulders forming an inclined plane on which come slide the radial extensions of the buckets during their separation of the plate by a rotational movement.
- the buckets have a individual identification marking.
- the plate presents an individual identification mark.
- the marks of identification are constituted by barcodes embedded in the plastic material.
- the identification marks are constituted by means likely to be read remotely, embedded in the plastic material.
- Figure 1 represents a three quarter view before a plate according to the invention.
- the plate is made by molding plastic material. She presents an upper surface (1) extended by a border peripheral (2).
- the peripheral border (2) is convergent to allow stacking or partial nesting of superimposed plates.
- the upper surface (1) has a plurality of buckets (3) whose opening is surrounded by a crown (4) notched.
- This crown can receive a key (5) of complementary section.
- This key (5) allows to exercise on the crown (4) of a bucket a twisting torque producing a rupture of the breakable zone (6) surrounding the bucket.
- FIG. 2 shows a three quarter view rear of a plate according to the invention.
- the bucket (3) has the shape of a hollow cylindrical body (7).
- the bucket height is slightly lower than that of the peripheral edge (2), so as to allow the plate to rest in stable equilibrium on a flat surface.
- FIG. 3 represents an enlarged view of above, the plate.
- the crown (4) is of notched shape and presents an alternation of grooves (9) and bosses salient (10).
- the crown (4) also presents radial extensions (11, 12) constituting zones of enhancement.
- the connection between the crown (4) and the surface of the plate (1) is by a zone weakening (13) surrounding the crown.
- the attenuation is achieved by a thickness reduced plastic material facilitating breakage when an effort is exerted on the crown, particularly using the key (5) to transmit a pair of torsion.
- FIG. 4 represents an enlarged view of below.
- the cylindrical body (7) is surrounded by the zone weakening.
- the plate has zones (14) in shape of helical ramp on which slip radial extensions (11).
- the plate can be made by molding in a single drawer mold.
- the plates can each carry a means specific identification, for example a barcode, a two-dimensional code molded in the plastic material.
- each bucket can carry specific identification means, for example a code bars, a two-dimensional code molded into the bottom of the cylindrical part.
- each plate a coded radio frequency or magnetic tag.
- This label which can take different forms, for example the shape of an integrated circuit or a coded magnetic wire, can be integrated into the material, to allow a remote identification.
- This identification may relate either to the plate, either on the bucket.
- the marking of each bucket is identical, and possibly identical to that of the plate.
- the plate can be marked with a unique code, and the buckets marked with a code including the identification code of the plate completed with a code specific to the bucket.
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- General Health & Medical Sciences (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Sampling And Sample Adjustment (AREA)
- Devices For Use In Laboratory Experiments (AREA)
- Details Of Rigid Or Semi-Rigid Containers (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Closures For Containers (AREA)
- Analysing Materials By The Use Of Radiation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9808996 | 1998-07-13 | ||
| FR9808996A FR2780903B1 (fr) | 1998-07-13 | 1998-07-13 | Plaque destinee notamment au microtitrage, presentant une pluralite de godets pour recevoir des echantillons d'un liquide biologique |
| PCT/FR1999/001720 WO2000002661A1 (fr) | 1998-07-13 | 1999-07-13 | Plaque pour l'analyse biologique et la conservation d'echantillons biologique |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EP1096999A1 EP1096999A1 (fr) | 2001-05-09 |
| EP1096999B1 true EP1096999B1 (fr) | 2003-10-01 |
Family
ID=9528605
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP99929483A Expired - Lifetime EP1096999B1 (fr) | 1998-07-13 | 1999-07-13 | Plaque pour l'analyse biologique et la conservation d'echantillons biologiques |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US6540965B2 (enExample) |
| EP (1) | EP1096999B1 (enExample) |
| JP (1) | JP4377548B2 (enExample) |
| AT (1) | ATE250979T1 (enExample) |
| AU (1) | AU4628499A (enExample) |
| CA (1) | CA2337338C (enExample) |
| DE (1) | DE69911783T2 (enExample) |
| ES (1) | ES2209455T3 (enExample) |
| FR (1) | FR2780903B1 (enExample) |
| PT (1) | PT1096999E (enExample) |
| WO (1) | WO2000002661A1 (enExample) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10013240A1 (de) * | 2000-03-09 | 2001-10-11 | Brand Gmbh & Co Kg | Anordnung zu kontaminationsfreier Bearbeitung von insbesondere molekularbiologischen Reaktionsabläufen, Verschlußträger und Einzelverschluß für eine solche Anordnung sowie Vorrats-und Abgabeanordnung für Einzelverschlüsse |
| US7347977B2 (en) * | 2000-06-08 | 2008-03-25 | Eppendorf Ag | Microtitration plate |
| EP1348485A1 (en) * | 2002-02-28 | 2003-10-01 | The Automation Partnership (Cambridge) Limited | Sample handling system and method |
| US7126479B2 (en) | 2004-08-17 | 2006-10-24 | Francis M. Claessens | Metal container closure having integral RFID tag |
| US7061382B2 (en) | 2003-12-12 | 2006-06-13 | Francis M. Claessens | Apparatus for electronically verifying the authenticity of contents within a container |
| US7017807B2 (en) | 2003-09-08 | 2006-03-28 | Francis M. Claessens | Apparatus and method for detecting tampering with containers and preventing counterfeiting thereof |
| JP4489082B2 (ja) | 2003-12-12 | 2010-06-23 | クレセンス、フランシス・エム | 製品に対する税が支払われているか否かを電子的に判定するための装置 |
| US7219800B2 (en) * | 2004-02-20 | 2007-05-22 | Eppendorf Ag | Modular array arrangements |
| US20050186578A1 (en) * | 2004-02-20 | 2005-08-25 | Sven Bulow | Chamber array arrangement |
| GB2428794A (en) * | 2005-08-02 | 2007-02-07 | Advanced Biotech Ltd | Two part microwell plate and method of fabricating same |
| US7688207B2 (en) * | 2006-07-28 | 2010-03-30 | Abbott Laboratories Inc. | System for tracking vessels in automated laboratory analyzers by radio frequency identification |
| EP2030683B1 (de) * | 2007-08-17 | 2013-10-02 | Qiagen GmbH | Vorrichtung und Verfahren zur Entnahme von Substanzen aus vorgefüllten Behältnissen |
| US20100059461A1 (en) * | 2008-09-05 | 2010-03-11 | David Landsberger | Container rack with locking member |
| UA116760C2 (uk) * | 2011-04-07 | 2018-05-10 | Біі Векторінг Течнолоґи Інк. | Пристрій для обробки рослин |
| CA2962489C (en) * | 2014-10-08 | 2019-02-12 | Graphic Packaging International, Inc. | Carrier with receiving and retention features |
| CA3015222A1 (en) * | 2016-03-02 | 2017-09-08 | Becton, Dickinson And Company | Packaging and devices to access screw-top containers in automated systems |
| JP6053979B1 (ja) * | 2016-07-04 | 2016-12-27 | 株式会社 京埼工業 | 連結キャップ |
| JP2019162579A (ja) * | 2018-03-19 | 2019-09-26 | 株式会社リコー | 容器の一体化キット、並びに、それに用いる容器及び容器保持具 |
| USD920536S1 (en) | 2018-09-28 | 2021-05-25 | Becton, Dickinson And Company | Reagent plate |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3907505A (en) * | 1973-05-30 | 1975-09-23 | Miles Lab | Selectively detachable apparatus |
| US4154795A (en) * | 1976-07-23 | 1979-05-15 | Dynatech Holdings Limited | Microtest plates |
| US4255522A (en) * | 1978-07-01 | 1981-03-10 | Deutsches Krebsforschungszentrum | Petri dish |
| BE902982A (nl) * | 1985-07-29 | 1985-11-18 | Lisens John | Klasseerelement voor stalen en bloedstaalklasseerinrichting ermee opgebouwd. |
| US5110556A (en) * | 1986-10-28 | 1992-05-05 | Costar Corporation | Multi-well test plate |
| US4829006A (en) * | 1988-02-01 | 1989-05-09 | Difco Laboratories | Centrifugation vial and cluster tray |
| US4877659A (en) * | 1988-08-02 | 1989-10-31 | Inti Corporation | Multiwell assay/culture strip |
| FI87278C (fi) * | 1989-08-28 | 1992-12-10 | Labsystems Oy | Kyvettmatris och staellning foer denna |
| US5207150A (en) * | 1992-05-21 | 1993-05-04 | Wellman Leo F | Baking tray apparatus |
| CA2114527A1 (en) * | 1992-06-29 | 1994-01-06 | Dade International Inc. | Sample tube carrier |
| US5366893A (en) * | 1993-01-13 | 1994-11-22 | Becton, Dickinson And Company | Culture vessel |
| FR2704527B1 (fr) * | 1993-04-26 | 1995-06-30 | Oreal | Combinaison d'une batterie de recipients et d'une barrette de capuchons, et ensemble d'un recipient et d'un capuchon. |
| DE4417513A1 (de) * | 1994-05-19 | 1995-11-23 | Fazit Gmbh Formgestaltung Entw | Codierbarer Behälter |
| US5514343A (en) * | 1994-06-22 | 1996-05-07 | Nunc, As | Microtitration system |
| US5683659A (en) * | 1995-02-22 | 1997-11-04 | Hovatter; Kenneth R. | Integral assembly of microcentrifuge strip tubes and strip caps |
| US5603899A (en) * | 1995-04-12 | 1997-02-18 | Pharmacia Biotech, Inc. | Multiple column chromatography assembly |
| US5800778A (en) * | 1995-05-31 | 1998-09-01 | Biomerieux Vitek, Inc. | Sealant for sample holder |
| US5899353A (en) * | 1995-06-07 | 1999-05-04 | Sabin; Jeffrey Michael | Ice cream cone cake holder |
| US5948363A (en) * | 1996-04-22 | 1999-09-07 | Gaillard; Patrick | Micro-well strip with print tabs |
| US5800784A (en) * | 1996-07-09 | 1998-09-01 | Horn; Marcus J. | Chemical sample treatment system and cassette, and methods for effecting multistep treatment process |
| US5670118A (en) * | 1996-07-25 | 1997-09-23 | Dynex Technologies, Inc. | Color coded test wells |
| NL1003726C2 (nl) * | 1996-08-01 | 1998-02-05 | Micronic B V | Reageerbuis met optisch leesbare codering. |
| US5795748A (en) * | 1996-09-26 | 1998-08-18 | Becton Dickinson And Company | DNA microwell device and method |
| US6001310A (en) * | 1996-10-11 | 1999-12-14 | Shaffer; John V. | Pliable centrifuge tube array |
| US6000535A (en) * | 1998-02-18 | 1999-12-14 | Pulpdent Corporation | Disposable mixing wells |
| US6106783A (en) * | 1998-06-30 | 2000-08-22 | Microliter Analytical Supplies, Inc. | Microplate assembly and closure |
-
1998
- 1998-07-13 FR FR9808996A patent/FR2780903B1/fr not_active Expired - Lifetime
-
1999
- 1999-07-13 PT PT99929483T patent/PT1096999E/pt unknown
- 1999-07-13 EP EP99929483A patent/EP1096999B1/fr not_active Expired - Lifetime
- 1999-07-13 ES ES99929483T patent/ES2209455T3/es not_active Expired - Lifetime
- 1999-07-13 AU AU46284/99A patent/AU4628499A/en not_active Abandoned
- 1999-07-13 AT AT99929483T patent/ATE250979T1/de active
- 1999-07-13 JP JP2000558914A patent/JP4377548B2/ja not_active Expired - Fee Related
- 1999-07-13 CA CA002337338A patent/CA2337338C/fr not_active Expired - Fee Related
- 1999-07-13 WO PCT/FR1999/001720 patent/WO2000002661A1/fr not_active Ceased
- 1999-07-13 DE DE69911783T patent/DE69911783T2/de not_active Expired - Lifetime
-
2001
- 2001-01-09 US US09/757,282 patent/US6540965B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| AU4628499A (en) | 2000-02-01 |
| JP2002520579A (ja) | 2002-07-09 |
| US20010005491A1 (en) | 2001-06-28 |
| FR2780903B1 (fr) | 2000-09-29 |
| US6540965B2 (en) | 2003-04-01 |
| EP1096999A1 (fr) | 2001-05-09 |
| DE69911783T2 (de) | 2004-09-02 |
| DE69911783D1 (de) | 2003-11-06 |
| FR2780903A1 (fr) | 2000-01-14 |
| CA2337338A1 (fr) | 2000-01-20 |
| CA2337338C (fr) | 2010-01-12 |
| WO2000002661A1 (fr) | 2000-01-20 |
| PT1096999E (pt) | 2004-02-27 |
| ATE250979T1 (de) | 2003-10-15 |
| ES2209455T3 (es) | 2004-06-16 |
| JP4377548B2 (ja) | 2009-12-02 |
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