EP1072238B1 - Externes, magnetisches betätigungsventil für einen künstlichen intraurethalen sphinkter - Google Patents
Externes, magnetisches betätigungsventil für einen künstlichen intraurethalen sphinkter Download PDFInfo
- Publication number
- EP1072238B1 EP1072238B1 EP00903705A EP00903705A EP1072238B1 EP 1072238 B1 EP1072238 B1 EP 1072238B1 EP 00903705 A EP00903705 A EP 00903705A EP 00903705 A EP00903705 A EP 00903705A EP 1072238 B1 EP1072238 B1 EP 1072238B1
- Authority
- EP
- European Patent Office
- Prior art keywords
- valve
- urinary sphincter
- piston
- external
- magnet
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/0004—Closure means for urethra or rectum, i.e. anti-incontinence devices or support slings against pelvic prolapse
- A61F2/0009—Closure means for urethra or rectum, i.e. anti-incontinence devices or support slings against pelvic prolapse placed in or outside the body opening close to the surface of the body
- A61F2/0018—Closure means for urethra or rectum, i.e. anti-incontinence devices or support slings against pelvic prolapse placed in or outside the body opening close to the surface of the body magnetic
Definitions
- the present invention relates to a valve model for an artificial urinary sphincter to be placed intraurethrally in humans, which performs the functions of the external urinary sphincter, meant for treating urinary incontinence and/or retention. Opening of said valve is controlled from outside the human body by the application of a magnetic field created by a permanent magnet. The valve is closed automatically by a permanent magnet placed inside the valve.
- the purpose of the present invention is the recovery of self-control of urination for those people who have lost it by means of an easily implanted prosthesis.
- An external magnetically actuated valve according to the preamble of claim 1, is known from the document WO-A- 95 29716.
- the device object of the present invention allows control of urination by the patient and may be implanted without need of surgery by cytoscopy.
- the external magnetically actuated valve for an artificial intraurethral sphincter is in essence a tightly sealed fluid valve provided with a securing system similar to that used for urethral probes, which may be implanted by cytoscopy.
- Two valve models are proposed, named “valve 1" and “valve 2", with different geometry but with the same working principle as described above:
- an external magnet (11) is used to open the valve.
- said magnet When said magnet approaches the area where the valve is implanted from outside the human body, it exerts on piston (6) a greater attraction than that of internal toroidal magnet (3) in an opposite sense, due to the reorientation of the magnetic moment of piston (6), resulting in the valve opening and urine being released outwards.
- outer magnet (6) When outer magnet (6) is removed, the force exerted by toroidal magnet (3) on piston (6) again closes the valve inlet orifice shutting off urine flow outwards.
- This valve is further provided with a safety system based on the weakening of the magnetic field with distance.
- the present invention relates to an external magnetically actuated valve for an artificial intraurethral urinary sphincter and is illustrated by the following examples:
- the soft magntic materials used were sweet Fe, Fe-Si and Fe-P.
- the hard magnetic materiasl were magnets of NdFeB, SmCo and AlNiCo. These prototypes were tested in vitro in a hydrodynamical facility in which the tight seal, functioning of teh safety system, opening of the valve by applicaiton of an external magnetic field, evacuation flow and automatic closing were tested.
- a hollow cylindrical body which conforms the valve body was made in Teflon. Said body is provided with a cavity in the inlet orifice in which is placed the internal magnet under pressure.
- the permanent internal magnet is made of NdFeB and is coated in Teflon to avoid biologic incompatibilities.
- the pistons, which have a triangular base and a cone-shaped end are made of sweet Fe and coated in Teflon for the same reasons as above.
- the external permanent magnet is made of NdFeB.
- the prototypes were inserted by urologist surgeons using surgical techniques in two pigs, one male and one female, in which a chronic urinary incontinence had been previously caused. Tight seal of the valve was tested to a pressure of 40 cm. H 2 O. When the external magnet was placed near the valve, which was already in teh animal's urethra, the animal's urine was evacuated.
Landscapes
- Health & Medical Sciences (AREA)
- Urology & Nephrology (AREA)
- Cardiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Prostheses (AREA)
- External Artificial Organs (AREA)
- Electromagnets (AREA)
- Magnetically Actuated Valves (AREA)
Claims (5)
- Magnetisches externes Auslöseventil für einen künstlichen intraurethralen Urinsphinkter, der sich aus Folgendem zusammensetzt:einem hohlen zylindrischen Körper (1), der aus biokompatiblem Material hergestellt ist.einem Kolben (6), der aus , magnetischem Material hergestellt ist und dessen eines Ende kegelförmig oder halbrund ausgebildet ist und sich im Inneren des zylindrischen Körpers bewegt, dadurch gekennzeichnet, dass er ausserdem über einen permanenten ringförmigen Magneten (3), der an der Eintrittsöffnung des zylindrischen Körpers des Ventils befestigt ist, verfügt.
- Magnetisches externes Auslöseventil für einen künstlichen intraurethralen Urinsphinkter, gemäss des vorangehenden Anspruchs, dadurch gekennzeichnet, dass der Kolben einen dreieckigen oder runden Querschnitt aufweist.
- Magnetisches externes Auslöseventil für einen künstlichen intraurethralen Urinsphinkter, gemäss Anspruch 1, dadurch gekennzeichnet, dass das Schliessen des Ventils durch die Anziehungskraft stattfindet, die der permanente Magnet auf den inneren Kolben ausübt.
- Magnetisches externes Auslöseventil für einen künstlichen intraurethralen Urinsphinkter, gemäss den vorangehenden Ansprüchen, dadurch gekennzeichnet, dass die Öffnung des Ventils von Aussen durch die Annäherung eines externen Magnets stattfindet, der auf den Kolben eine höhere Kraft ausübt, als die des inneren ringförmigen Magnets und in die umgekehrte Richtung, so dass der Urin nach Aussen gelangen kann.
- Magnetisches externes Auslöseventil für einen künstlichen intraurethralen Urinsphinkter, gemäss den vorangehenden Ansprüchen, dadurch gekennzeichnet, dass es über ein Sicherheitssystem verfügt, dass auf der abnehmenden Kraft zwischen dem internen Magneten und dem Kolben beruht, da das Magnetfeld mit zunehmender Entfernung abnimmt.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES009900284A ES2150881B1 (es) | 1999-02-11 | 1999-02-11 | Valvula de accionamiento magnetico externo para un esfinter urinario artificial intrauretral. |
ES9900284 | 1999-02-11 | ||
PCT/ES2000/000049 WO2000047141A1 (es) | 1999-02-11 | 2000-02-11 | Valvula de accionamiento magnetico externo para un esfinter urinario artificial intrauretral |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1072238A1 EP1072238A1 (de) | 2001-01-31 |
EP1072238B1 true EP1072238B1 (de) | 2003-11-26 |
Family
ID=8307291
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP00903705A Expired - Lifetime EP1072238B1 (de) | 1999-02-11 | 2000-02-11 | Externes, magnetisches betätigungsventil für einen künstlichen intraurethalen sphinkter |
Country Status (11)
Country | Link |
---|---|
US (1) | US6623421B1 (de) |
EP (1) | EP1072238B1 (de) |
JP (1) | JP2002536116A (de) |
AT (1) | ATE254895T1 (de) |
AU (1) | AU760625B2 (de) |
CA (1) | CA2328148C (de) |
DE (1) | DE60006748T2 (de) |
DK (1) | DK1072238T3 (de) |
ES (1) | ES2150881B1 (de) |
PT (1) | PT1072238E (de) |
WO (1) | WO2000047141A1 (de) |
Cited By (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7931582B2 (en) | 2000-02-11 | 2011-04-26 | Obtech Medical Ag | Controlled impotence treatment |
US8096939B2 (en) | 2000-02-10 | 2012-01-17 | Obtech Medical Ag | Urinary incontinence treatment with wireless energy supply |
US8096938B2 (en) | 1999-08-12 | 2012-01-17 | Obtech Medical Ag | Controlled anal incontinence disease treatment |
US8126558B2 (en) | 2000-02-14 | 2012-02-28 | Obtech Medical Ag | Controlled penile prosthesis |
US8287444B2 (en) | 2000-02-10 | 2012-10-16 | Obtech Medical Ag | Mechanical impotence treatment apparatus |
US8290594B2 (en) | 2000-02-11 | 2012-10-16 | Obtech Medical Ag | Impotence treatment apparatus with energy transforming means |
US8313423B2 (en) | 2000-02-14 | 2012-11-20 | Peter Forsell | Hydraulic anal incontinence treatment |
US8509894B2 (en) | 2008-10-10 | 2013-08-13 | Milux Holding Sa | Heart help device, system, and method |
US8545384B2 (en) | 1999-08-12 | 2013-10-01 | Obtech Medical Ag | Anal incontinence disease treatment with controlled wireless energy supply |
US8556796B2 (en) | 2000-02-10 | 2013-10-15 | Obtech Medical Ag | Controlled urinary incontinence treatment |
US8600510B2 (en) | 2008-10-10 | 2013-12-03 | Milux Holding Sa | Apparatus, system and operation method for the treatment of female sexual dysfunction |
US8636809B2 (en) | 2008-01-29 | 2014-01-28 | Milux Holding Sa | Device for treating obesity |
US8678997B2 (en) | 2000-02-14 | 2014-03-25 | Obtech Medical Ag | Male impotence prosthesis apparatus with wireless energy supply |
US8696745B2 (en) | 2008-10-10 | 2014-04-15 | Kirk Promotion Ltd. | Heart help device, system, and method |
US8734318B2 (en) | 2000-02-11 | 2014-05-27 | Obtech Medical Ag | Mechanical anal incontinence |
US8764627B2 (en) | 2000-02-14 | 2014-07-01 | Obtech Medical Ag | Penile prosthesis |
US8874215B2 (en) | 2008-10-10 | 2014-10-28 | Peter Forsell | System, an apparatus, and a method for treating a sexual dysfunctional female patient |
US8961448B2 (en) | 2008-01-28 | 2015-02-24 | Peter Forsell | Implantable drainage device |
US9278158B2 (en) | 2002-07-29 | 2016-03-08 | Peter Forsell | Multi-material incontinence treatment construction device |
US9427301B2 (en) | 2002-07-29 | 2016-08-30 | Peter Forsell | Durable implant |
US9763762B2 (en) | 2013-09-25 | 2017-09-19 | Medtronic, Inc. | Implantable urinary tract valve |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6709385B2 (en) | 2000-02-11 | 2004-03-23 | Obtech Medical Ag | Urinary incontinence treatment apparatus |
ATE293941T1 (de) * | 2000-02-14 | 2005-05-15 | Potencia Medical Ag | Hydraulisches gerät zur behandlung von harninkontinenz |
ES2214117B1 (es) * | 2002-10-22 | 2006-02-16 | Laboratorios Indas, S.A. | Esfinter artificial intrauretral de accionamiento magnetico para pacientes femeninos. |
EP1784143A2 (de) * | 2004-08-25 | 2007-05-16 | Pavad Medical, Inc. | Künstlicher sphinkter |
US20070276342A1 (en) * | 2006-03-28 | 2007-11-29 | Bryant Lin | Devices and related methods for treating incontinence |
CA2776467A1 (en) | 2008-10-10 | 2010-04-15 | Peter Forsell | Fastening means for implantable medical control assembly |
EP3851076A1 (de) | 2008-10-10 | 2021-07-21 | MedicalTree Patent Ltd. | Verbesserte künstliche herzklappe |
EP2422755B1 (de) * | 2009-04-20 | 2016-05-04 | Cheiron Japan Co. | Urinationssteuervorrichtung |
US9949812B2 (en) | 2009-07-17 | 2018-04-24 | Peter Forsell | Vaginal operation method for the treatment of anal incontinence in women |
US10952836B2 (en) | 2009-07-17 | 2021-03-23 | Peter Forsell | Vaginal operation method for the treatment of urinary incontinence in women |
EP2531247B1 (de) | 2010-02-04 | 2017-01-04 | Guillermo L. Pol | Medizinische tubi zur selektiven mechanischen beatmung der lungen |
DE102010064211B4 (de) * | 2010-12-27 | 2014-12-31 | Otto-Von-Guericke-Universität Magdeburg Medizinische Fakultät | Öffenbare Verschlusseinrichtung für die Harnröhre |
CN102370529A (zh) * | 2011-10-24 | 2012-03-14 | 广东工业大学 | 一种体外交变磁场驱动的膀胱排尿泵 |
ITPI20120025A1 (it) | 2012-03-17 | 2013-09-18 | Giuliani Giuseppe | Struttura di sfintere uretro-vescicale endouretrale |
KR101445975B1 (ko) | 2013-06-17 | 2014-09-29 | 서울대학교산학협력단 | 자기력 기반의 이식형 약물 전달 장치 |
DK178335B1 (en) * | 2014-05-28 | 2015-12-21 | Magcath Aps | A urine flow control system and a magnetic actuator device |
US11324512B2 (en) * | 2018-10-26 | 2022-05-10 | Torax Medical, Inc. | Magnetic sphincter augmentation device for urinary incontinence |
CN110840507B (zh) * | 2019-11-22 | 2021-08-20 | 北京泌康医疗科技有限公司 | 具有多点轮流切换功能的尿失禁自动控制系统及其体内机 |
US11865270B2 (en) | 2020-01-16 | 2024-01-09 | Starling Medical, Inc. | Bodily fluid management system |
KR102369030B1 (ko) * | 2020-02-20 | 2022-02-28 | 한양대학교 산학협력단 | 인공 괄약 장치 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL8403174A (nl) * | 1984-10-17 | 1986-05-16 | Franciscus Jacobus Maria De Vr | Implanteerbare afsluitinrichting. |
US4850963A (en) * | 1986-06-11 | 1989-07-25 | Utah Bioresearch, Inc. | Apparatus and methods for achieving urinary continence |
US4994019A (en) * | 1989-07-28 | 1991-02-19 | Micro-Magnetics, Inc. | Magnetic occluding device |
CA2020881C (en) * | 1989-08-29 | 2002-04-02 | Carl Barwick | Urethral indwelling catheter with magnetically controlled drainage valve and method |
US5030199A (en) * | 1989-12-11 | 1991-07-09 | Medical Engineering Corporation | Female incontinence control device with magnetically operable valve and method |
SE504276C2 (sv) * | 1993-12-30 | 1996-12-23 | Siko Medical Ab | Ventil avsedd att placeras i urinröret |
US5762599A (en) * | 1994-05-02 | 1998-06-09 | Influence Medical Technologies, Ltd. | Magnetically-coupled implantable medical devices |
US5562598A (en) * | 1994-09-20 | 1996-10-08 | Whalen Biomedical Inc. | Artificial urethral sphincter |
FR2769491B1 (fr) | 1997-10-15 | 2000-01-07 | Patrick Sangouard | Sphincter artificiel reglable a commande magnetique |
WO1999051293A1 (de) * | 1998-04-05 | 1999-10-14 | Johannes Dohmen | Harnblasenhalsdauerkatheter mit berührungslos steuerbarer vorrichtung zum öffnen und schliessen für die entleerung der harnflüssigkeit |
US6066088A (en) * | 1998-07-13 | 2000-05-23 | Phillip Davis Inventions, Inc. | Intraurethral magnetic valve |
-
1999
- 1999-02-11 ES ES009900284A patent/ES2150881B1/es not_active Expired - Fee Related
-
2000
- 2000-02-11 EP EP00903705A patent/EP1072238B1/de not_active Expired - Lifetime
- 2000-02-11 AT AT00903705T patent/ATE254895T1/de not_active IP Right Cessation
- 2000-02-11 US US09/673,162 patent/US6623421B1/en not_active Expired - Fee Related
- 2000-02-11 DE DE60006748T patent/DE60006748T2/de not_active Expired - Fee Related
- 2000-02-11 JP JP2000598095A patent/JP2002536116A/ja active Pending
- 2000-02-11 DK DK00903705T patent/DK1072238T3/da active
- 2000-02-11 CA CA002328148A patent/CA2328148C/en not_active Expired - Fee Related
- 2000-02-11 PT PT00903705T patent/PT1072238E/pt unknown
- 2000-02-11 AU AU25495/00A patent/AU760625B2/en not_active Ceased
- 2000-02-11 WO PCT/ES2000/000049 patent/WO2000047141A1/es active IP Right Grant
Cited By (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8096938B2 (en) | 1999-08-12 | 2012-01-17 | Obtech Medical Ag | Controlled anal incontinence disease treatment |
US8545384B2 (en) | 1999-08-12 | 2013-10-01 | Obtech Medical Ag | Anal incontinence disease treatment with controlled wireless energy supply |
US8556796B2 (en) | 2000-02-10 | 2013-10-15 | Obtech Medical Ag | Controlled urinary incontinence treatment |
US8096939B2 (en) | 2000-02-10 | 2012-01-17 | Obtech Medical Ag | Urinary incontinence treatment with wireless energy supply |
US8287444B2 (en) | 2000-02-10 | 2012-10-16 | Obtech Medical Ag | Mechanical impotence treatment apparatus |
US8602966B2 (en) | 2000-02-10 | 2013-12-10 | Obtech Medical, AG | Mechanical impotence treatment apparatus |
US8734318B2 (en) | 2000-02-11 | 2014-05-27 | Obtech Medical Ag | Mechanical anal incontinence |
US8290594B2 (en) | 2000-02-11 | 2012-10-16 | Obtech Medical Ag | Impotence treatment apparatus with energy transforming means |
US7931582B2 (en) | 2000-02-11 | 2011-04-26 | Obtech Medical Ag | Controlled impotence treatment |
US8126558B2 (en) | 2000-02-14 | 2012-02-28 | Obtech Medical Ag | Controlled penile prosthesis |
US8313423B2 (en) | 2000-02-14 | 2012-11-20 | Peter Forsell | Hydraulic anal incontinence treatment |
US8678997B2 (en) | 2000-02-14 | 2014-03-25 | Obtech Medical Ag | Male impotence prosthesis apparatus with wireless energy supply |
US8764627B2 (en) | 2000-02-14 | 2014-07-01 | Obtech Medical Ag | Penile prosthesis |
US9278158B2 (en) | 2002-07-29 | 2016-03-08 | Peter Forsell | Multi-material incontinence treatment construction device |
US9427301B2 (en) | 2002-07-29 | 2016-08-30 | Peter Forsell | Durable implant |
US8961448B2 (en) | 2008-01-28 | 2015-02-24 | Peter Forsell | Implantable drainage device |
US8636809B2 (en) | 2008-01-29 | 2014-01-28 | Milux Holding Sa | Device for treating obesity |
US9060771B2 (en) | 2008-01-29 | 2015-06-23 | Peter Forsell | Method and instrument for treating obesity |
US8696745B2 (en) | 2008-10-10 | 2014-04-15 | Kirk Promotion Ltd. | Heart help device, system, and method |
US8874215B2 (en) | 2008-10-10 | 2014-10-28 | Peter Forsell | System, an apparatus, and a method for treating a sexual dysfunctional female patient |
US9072907B2 (en) | 2008-10-10 | 2015-07-07 | Peter Forsell | Heart help device, system, and method |
US8600510B2 (en) | 2008-10-10 | 2013-12-03 | Milux Holding Sa | Apparatus, system and operation method for the treatment of female sexual dysfunction |
US9370656B2 (en) | 2008-10-10 | 2016-06-21 | Peter Forsell | System, an apparatus, and a method for treating a sexual dysfunctional female patient |
US8509894B2 (en) | 2008-10-10 | 2013-08-13 | Milux Holding Sa | Heart help device, system, and method |
US9526649B2 (en) | 2008-10-10 | 2016-12-27 | Peter Forsell | Method and instrument for treating obesity |
US9763762B2 (en) | 2013-09-25 | 2017-09-19 | Medtronic, Inc. | Implantable urinary tract valve |
US10575935B2 (en) | 2013-09-25 | 2020-03-03 | Medtronic, Inc. | Implantable urinary tract valve |
Also Published As
Publication number | Publication date |
---|---|
US6623421B1 (en) | 2003-09-23 |
WO2000047141A1 (es) | 2000-08-17 |
CA2328148C (en) | 2008-10-14 |
DK1072238T3 (da) | 2004-04-05 |
ES2150881A1 (es) | 2000-12-01 |
ATE254895T1 (de) | 2003-12-15 |
AU760625B2 (en) | 2003-05-22 |
DE60006748T2 (de) | 2004-12-23 |
PT1072238E (pt) | 2004-04-30 |
ES2150881B1 (es) | 2002-02-16 |
CA2328148A1 (en) | 2000-08-17 |
AU2549500A (en) | 2000-08-29 |
DE60006748D1 (de) | 2004-01-08 |
JP2002536116A (ja) | 2002-10-29 |
EP1072238A1 (de) | 2001-01-31 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EP1072238B1 (de) | Externes, magnetisches betätigungsventil für einen künstlichen intraurethalen sphinkter | |
US5004454A (en) | Auxiliary intra-urethral magnetic valve for persons suffering from urinary incontinence | |
US3768102A (en) | Implantable artificial urethral valve | |
CA2337036C (en) | Intraurethral magnetic valve | |
US3939821A (en) | Magnetically actuated tube compressing valve | |
US4994019A (en) | Magnetic occluding device | |
US7803106B2 (en) | Urinary flow control device and method | |
US5997467A (en) | Urinary incontinence device | |
US20080269546A1 (en) | Self-acting urethral valve | |
EP0691138A1 (de) | Magnetische Kappe für eine medizinische Vorrichtung | |
NL9002710A (nl) | Werkwijze voor het regelen van incontinentie bij vrouwen en inrichting voor het toepassen van deze werkwijze. | |
WO2002053063A2 (en) | Urinary incontinence device | |
EP2572672B1 (de) | Synthetische Harnröhre mit Verschlussvorrichtung | |
JPH01285263A (ja) | 尿失禁抑能力を得る装置及び方法 | |
US20120239006A1 (en) | External control valve for indwelling urethral catheters | |
EP1913904A1 (de) | Magnetbetätigter künstlicher intraurethraler schliessmuskel für weibliche patienten | |
WO1995021641A1 (en) | Valve apparatus | |
CN110270008B (zh) | 一种磁控尿道阀 | |
CN208447849U (zh) | 一种尿道控尿器 | |
PL234224B1 (pl) | Sztuczny zwieracz hydrauliczny cewki moczowej otwierany magnetycznie |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20001030 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE |
|
GRAH | Despatch of communication of intention to grant a patent |
Free format text: ORIGINAL CODE: EPIDOS IGRA |
|
GRAS | Grant fee paid |
Free format text: ORIGINAL CODE: EPIDOSNIGR3 |
|
GRAA | (expected) grant |
Free format text: ORIGINAL CODE: 0009210 |
|
AK | Designated contracting states |
Kind code of ref document: B1 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: ES Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20031126 |
|
REG | Reference to a national code |
Ref country code: GB Ref legal event code: FG4D |
|
RIN1 | Information on inventor provided before grant (corrected) |
Inventor name: TENDILLO CORTIJO, FRANCISCO JAVIER Inventor name: CARBALLIDO RODRIGUEZ, JOAQUIN Inventor name: GARCIA PAEZ, JOSE MARIA Inventor name: JORGE HERRERO, EDUARDO Inventor name: MULTIGNER DOMINGUEZ, MARTA Inventor name: RIVERO RODRIGUEZ, GUILLERMO |
|
REG | Reference to a national code |
Ref country code: CH Ref legal event code: EP |
|
REF | Corresponds to: |
Ref document number: 60006748 Country of ref document: DE Date of ref document: 20040108 Kind code of ref document: P |
|
REG | Reference to a national code |
Ref country code: IE Ref legal event code: FG4D |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: IE Payment date: 20040220 Year of fee payment: 5 |
|
REG | Reference to a national code |
Ref country code: SE Ref legal event code: TRGR |
|
REG | Reference to a national code |
Ref country code: GR Ref legal event code: EP Ref document number: 20040400713 Country of ref document: GR |
|
REG | Reference to a national code |
Ref country code: DK Ref legal event code: T3 |
|
RAP2 | Party data changed (patent owner data changed or rights of a patent transferred) |
Owner name: LABORATORIOS INDAS, S.A. |
|
REG | Reference to a national code |
Ref country code: PT Ref legal event code: PC4A Free format text: LABORATORIOS INDAS S.A. ES Effective date: 20040301 Ref country code: PT Ref legal event code: SC4A Free format text: AVAILABILITY OF NATIONAL TRANSLATION Effective date: 20040223 |
|
NLT2 | Nl: modifications (of names), taken from the european patent patent bulletin |
Owner name: LABORATORIOS INDAS, S.A. |
|
NLS | Nl: assignments of ep-patents |
Owner name: LABORATORIOS INDAS, S.A. |
|
REG | Reference to a national code |
Ref country code: CH Ref legal event code: PUE Owner name: LABORATORIOS INDAS, S.A. Free format text: UNIVERSIDAD COMPLUTENSE DE MADRID#RECTORADO AVENIDA DE SENECA, 2#E-28040 MADRID (ES) -TRANSFER TO- LABORATORIOS INDAS, S.A.#CAMINO DE LAS HUERTAS, 2 EDIF. INDAS#28223 POZUELO DE ALARCON (ES) Ref country code: CH Ref legal event code: NV Representative=s name: NOVAGRAAF INTERNATIONAL SA |
|
ET | Fr: translation filed | ||
PLBE | No opposition filed within time limit |
Free format text: ORIGINAL CODE: 0009261 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: NO OPPOSITION FILED WITHIN TIME LIMIT |
|
26N | No opposition filed |
Effective date: 20040827 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: IE Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20050211 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: MC Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20050228 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: FR Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20051031 |
|
REG | Reference to a national code |
Ref country code: IE Ref legal event code: MM4A |
|
REG | Reference to a national code |
Ref country code: FR Ref legal event code: ST Effective date: 20051031 |
|
REG | Reference to a national code |
Ref country code: FR Ref legal event code: RN |
|
REG | Reference to a national code |
Ref country code: FR Ref legal event code: FC |
|
REG | Reference to a national code |
Ref country code: GB Ref legal event code: 732E |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: IT Payment date: 20070608 Year of fee payment: 8 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: FR Payment date: 20070228 Year of fee payment: 8 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: AT Payment date: 20090227 Year of fee payment: 10 Ref country code: LU Payment date: 20090303 Year of fee payment: 10 Ref country code: DK Payment date: 20090224 Year of fee payment: 10 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: NL Payment date: 20090228 Year of fee payment: 10 Ref country code: FI Payment date: 20090227 Year of fee payment: 10 Ref country code: PT Payment date: 20090224 Year of fee payment: 10 Ref country code: DE Payment date: 20090209 Year of fee payment: 10 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: GR Payment date: 20090226 Year of fee payment: 10 Ref country code: GB Payment date: 20090326 Year of fee payment: 10 Ref country code: CH Payment date: 20090226 Year of fee payment: 10 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: BE Payment date: 20090310 Year of fee payment: 10 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: IT Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20080211 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: SE Payment date: 20090227 Year of fee payment: 10 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: MC Payment date: 20090226 Year of fee payment: 10 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: CY Payment date: 20090225 Year of fee payment: 10 |
|
REG | Reference to a national code |
Ref country code: PT Ref legal event code: MM4A Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 20100811 |
|
BERE | Be: lapsed |
Owner name: S.A. LABORATORIOS *INDAS Effective date: 20100228 |
|
REG | Reference to a national code |
Ref country code: NL Ref legal event code: V1 Effective date: 20100901 |
|
REG | Reference to a national code |
Ref country code: CH Ref legal event code: PL |
|
REG | Reference to a national code |
Ref country code: DK Ref legal event code: EBP |
|
EUG | Se: european patent has lapsed | ||
GBPC | Gb: european patent ceased through non-payment of renewal fee |
Effective date: 20100211 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: LI Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20100228 Ref country code: MC Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20100301 Ref country code: CH Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20100228 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: AT Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20100211 Ref country code: FI Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20100211 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: CY Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20100309 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: DK Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20100228 Ref country code: PT Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20100811 Ref country code: NL Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20100901 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: DE Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20100901 Ref country code: BE Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20100228 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: GB Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20100211 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: SE Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20100212 Ref country code: LU Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20100211 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: FR Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20050228 |