EP1012266A4 - GALECTIN 8, 9, 10 AND 10SV. - Google Patents

GALECTIN 8, 9, 10 AND 10SV.

Info

Publication number
EP1012266A4
EP1012266A4 EP97912689A EP97912689A EP1012266A4 EP 1012266 A4 EP1012266 A4 EP 1012266A4 EP 97912689 A EP97912689 A EP 97912689A EP 97912689 A EP97912689 A EP 97912689A EP 1012266 A4 EP1012266 A4 EP 1012266A4
Authority
EP
European Patent Office
Prior art keywords
galectine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP97912689A
Other languages
German (de)
English (en)
French (fr)
Other versions
EP1012266A1 (en
Inventor
Jian Ni
Reiner L Gentz
Steven M Ruben
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Human Genome Sciences Inc
Original Assignee
Human Genome Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Human Genome Sciences Inc filed Critical Human Genome Sciences Inc
Publication of EP1012266A1 publication Critical patent/EP1012266A1/en
Publication of EP1012266A4 publication Critical patent/EP1012266A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4726—Lectins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701—Details
    • G01N2333/4724—Lectins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Urology & Nephrology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cardiology (AREA)
  • Biochemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Vascular Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Transplantation (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Rheumatology (AREA)
  • General Physics & Mathematics (AREA)
EP97912689A 1996-10-09 1997-10-09 GALECTIN 8, 9, 10 AND 10SV. Withdrawn EP1012266A4 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US2809396P 1996-10-09 1996-10-09
WOPCT/US96/16565 1996-10-09
US9616565 1996-10-09
US28093P 1996-10-09
PCT/US1997/018261 WO1998015624A1 (en) 1996-10-09 1997-10-09 Galectin 8, 9, 10 and 10sv

Publications (2)

Publication Number Publication Date
EP1012266A1 EP1012266A1 (en) 2000-06-28
EP1012266A4 true EP1012266A4 (en) 2004-04-28

Family

ID=26703285

Family Applications (1)

Application Number Title Priority Date Filing Date
EP97912689A Withdrawn EP1012266A4 (en) 1996-10-09 1997-10-09 GALECTIN 8, 9, 10 AND 10SV.

Country Status (4)

Country Link
EP (1) EP1012266A4 (https=)
JP (1) JP2001501831A (https=)
CA (1) CA2268022A1 (https=)
WO (1) WO1998015624A1 (https=)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1311693A (zh) * 1998-06-03 2001-09-05 株式会社效应性细胞研究所 嗜酸性粒细胞趋化因子
CN1302881A (zh) 1999-10-28 2001-07-11 上海博容基因开发有限公司 一种新的多肽——人β－半乳糖苷结合蛋白和编码这种多肽的多核苷酸
US6953658B2 (en) 2000-03-09 2005-10-11 Diadexus, Inc. Method of diagnosing, monitoring, staging, imaging and treating gastrointestinal cancer
AU2002214256B2 (en) * 2000-11-01 2007-07-12 Galpharma Co., Ltd. Agent for detecting cancer's ability to metastasize
WO2003072606A2 (en) * 2002-02-28 2003-09-04 Yeda Research And Development Company Ltd. Galectin-8and functional derivatives as binding agents for cd44 glycoproteins and methods of use
US20030165965A1 (en) * 2002-03-01 2003-09-04 Helen Francis-Lang LGALS as modifiers of the CHK pathway and methods of use
US20060009378A1 (en) 2002-11-14 2006-01-12 Itshak Golan Novel galectin sequences and compositions and methods utilizing same for treating or diagnosing arthritis and other chronic inflammatory diseases
WO2004043332A2 (en) * 2002-11-14 2004-05-27 Yissum Research Development Company Of The Hebrew University Of Jerusalem Novel galectin sequences and compositions and methods utilizing same for treating or diagnosing arthritis and other chronic inflammatory diseases
US20060134119A1 (en) * 2003-01-24 2006-06-22 Mitsuomi Hirashima Drugs containing galectin 9
US20070042941A1 (en) * 2003-04-28 2007-02-22 Mitsuomi Hirashima Galectin 9-inducing factors
DE10333406A1 (de) * 2003-07-15 2005-02-10 Protagen Ag T-regulatorische-Zellen enthaltend Galectine zur Therapie und Diagnose von Erkrankungen
CA2541006C (en) * 2003-10-03 2015-02-17 Brigham And Women's Hospital Tim-3 polypeptides
TW200539890A (en) 2004-03-12 2005-12-16 Brigham & Womens Hospital Methods of modulating immune responses by modulating tim-1, tim-2 and tim-4 function
JP4792390B2 (ja) * 2004-03-29 2011-10-12 株式会社ガルファーマ 新規ガレクチン９改変体タンパク質及びその用途
EP1767634A4 (en) * 2004-06-14 2008-10-22 Galpharma Co Ltd NEW GALECTIN 8 MODIFICATION PROTEIN AND USE THEREOF
CN1332030C (zh) * 2005-04-28 2007-08-15 武汉大学 一种真菌半乳糖凝集素蛋白活性的多肽、其编码序列及制备方法和应用
JP2007131540A (ja) * 2005-11-08 2007-05-31 Galpharma Co Ltd Ｃｄ４４機能抑制因子による抗アレルギー薬、免疫抑制薬および抗腫瘍薬
CN102205111B (zh) * 2011-05-19 2013-01-23 武汉大学 杨树菇半乳糖凝集素在制备抗hiv感染药物中的用途
WO2014171018A1 (ja) * 2013-04-20 2014-10-23 株式会社ガルファーマ 疾患の診断方法、疾患の治療または予防方法、疾患の診断用キット、疾患の治療または予防用医薬
JP5420791B1 (ja) * 2013-08-23 2014-02-19 肇 福永 サルモネラ菌及びシート状ｍ細胞
IL314040A (en) * 2016-05-10 2024-09-01 Genentech Inc Methods of decreasing trisulfide bonds during recombinant production of polypeptides
JP7224583B2 (ja) * 2018-01-29 2023-02-20 日本メナード化粧品株式会社 ガレクチン－９産生促進剤
CN108409850A (zh) * 2018-01-30 2018-08-17 河南师范大学 一种鱼源半乳糖凝集素CaGal重组蛋白的制备方法及其应用
CN113999287B (zh) * 2021-12-02 2023-06-27 深圳湾实验室坪山生物医药研发转化中心 一种靶向半乳糖凝集素-10的多肽抑制剂及其制备方法和用途

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996021671A1 (en) * 1995-01-11 1996-07-18 The Trustees Of Columbia University In The City Of New York Development of dna probes and immunological reagents specific for cell surface-expressed molecules and transformation-associated genes
WO1996039419A1 (en) * 1995-06-06 1996-12-12 Human Genome Sciences, Inc. Colon specific genes and proteins
WO1997003190A1 (fr) * 1995-07-11 1997-01-30 Sagami Chemical Research Center PROTEINE HUMAINE SEMBLABLE A GALECTINE-4 ET ADNc CODANT CETTE PROTEINE

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996021671A1 (en) * 1995-01-11 1996-07-18 The Trustees Of Columbia University In The City Of New York Development of dna probes and immunological reagents specific for cell surface-expressed molecules and transformation-associated genes
WO1996039419A1 (en) * 1995-06-06 1996-12-12 Human Genome Sciences, Inc. Colon specific genes and proteins
WO1997003190A1 (fr) * 1995-07-11 1997-01-30 Sagami Chemical Research Center PROTEINE HUMAINE SEMBLABLE A GALECTINE-4 ET ADNc CODANT CETTE PROTEINE

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
HADARI ET AL: "Galectin-8: A new rat lectin, related to Galectin-4", THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 270, no. 7, February 1995 (1995-02-01), pages 3447 - 3453, XP002272060 *
HUFLEJT ET AL.: "Strikingly different localization of Galectin-3 and Galectin-4 in human colon adenocarcinoma T84 cells", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 272, no. 30, May 1997 (1997-05-01), pages 14294 - 14303, XP002272061 *
See also references of WO9815624A1 *
TÜRECI ET AL: "Molecular definition of a novel human galectin which is immunogenic in patients with Hodgkin's disease", THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 272, no. 10, March 1997 (1997-03-01), pages 6416 - 6422, XP002272062 *

Also Published As

Publication number Publication date
CA2268022A1 (en) 1998-04-16
WO1998015624A1 (en) 1998-04-16
EP1012266A1 (en) 2000-06-28
JP2001501831A (ja) 2001-02-13

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