EP0973394A4 - Acide nucleique et sequences d'acides amines relatifs a helicobacter pylori, et compositions de vaccins les contenant - Google Patents

Acide nucleique et sequences d'acides amines relatifs a helicobacter pylori, et compositions de vaccins les contenant

Info

Publication number
EP0973394A4
EP0973394A4 EP97913847A EP97913847A EP0973394A4 EP 0973394 A4 EP0973394 A4 EP 0973394A4 EP 97913847 A EP97913847 A EP 97913847A EP 97913847 A EP97913847 A EP 97913847A EP 0973394 A4 EP0973394 A4 EP 0973394A4
Authority
EP
European Patent Office
Prior art keywords
helicobacter pylori
vaccine compositions
amino acid
nucleic acid
acid sequences
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP97913847A
Other languages
German (de)
English (en)
Other versions
EP0973394A1 (fr
Inventor
Douglas Smith
Richard A Alm
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
AstraZeneca AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AstraZeneca AB filed Critical AstraZeneca AB
Publication of EP0973394A1 publication Critical patent/EP0973394A1/fr
Publication of EP0973394A4 publication Critical patent/EP0973394A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/205Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Campylobacter (G)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Analytical Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
EP97913847A 1996-10-28 1997-10-28 Acide nucleique et sequences d'acides amines relatifs a helicobacter pylori, et compositions de vaccins les contenant Withdrawn EP0973394A4 (fr)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US73915096A 1996-10-28 1996-10-28
US739150 1996-10-28
US75973996A 1996-12-06 1996-12-06
US89192897A 1997-07-14 1997-07-14
US891928 1997-07-14
PCT/US1997/019575 WO1998018323A1 (fr) 1996-10-28 1997-10-28 Acide nucleique et sequences d'acides amines relatifs a helicobacter pylori, et compositions de vaccins les contenant
US759739 2001-01-12

Publications (2)

Publication Number Publication Date
EP0973394A1 EP0973394A1 (fr) 2000-01-26
EP0973394A4 true EP0973394A4 (fr) 2005-03-30

Family

ID=27419246

Family Applications (1)

Application Number Title Priority Date Filing Date
EP97913847A Withdrawn EP0973394A4 (fr) 1996-10-28 1997-10-28 Acide nucleique et sequences d'acides amines relatifs a helicobacter pylori, et compositions de vaccins les contenant

Country Status (19)

Country Link
EP (1) EP0973394A4 (fr)
JP (1) JP2001504329A (fr)
KR (1) KR20000052831A (fr)
CN (1) CN1235513A (fr)
AR (1) AR009600A1 (fr)
AU (1) AU734052B2 (fr)
BR (1) BR9712587A (fr)
CA (1) CA2265523A1 (fr)
EE (1) EE9900176A (fr)
ID (1) ID22065A (fr)
IL (1) IL129397A0 (fr)
IS (1) IS5005A (fr)
NO (1) NO991995L (fr)
NZ (1) NZ334568A (fr)
PL (1) PL333169A1 (fr)
SA (1) SA98180918A (fr)
SK (1) SK34699A3 (fr)
TR (1) TR199900940T2 (fr)
WO (1) WO1998018323A1 (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE244578T1 (de) * 1993-07-27 2003-07-15 Csl Ltd Behandlung eines durch helicobakter verursachten gastroduodenalen krankheit
US6406703B1 (en) 1993-07-27 2002-06-18 Csl Limited Treatment of H. pylori associated gastroduodenal disease
DE19730425A1 (de) 1997-07-16 1999-01-21 Henkel Teroson Gmbh Heißhärtende wäschefeste Rohbau-Versiegelung
EP1108033A2 (fr) * 1998-07-27 2001-06-20 Aventis Pasteur Limited ANTIGENES DE $i(CHLAMYDIA) ET FRAGMENTS D'ADN CORRESPONDANTS, ET UTILISATIONS DE CEUX-CI
SE9901548D0 (sv) * 1999-04-29 1999-04-29 Astra Ab Helicobacter pylori antigens
GB9914945D0 (en) * 1999-06-25 1999-08-25 Smithkline Beecham Biolog Novel compounds
AUPQ347199A0 (en) * 1999-10-15 1999-11-11 Csl Limited Novel polypeptide fragments
CN101532001A (zh) 2000-03-08 2009-09-16 诺维信公司 具有改变的特性的变体
GB0010370D0 (en) * 2000-04-29 2000-06-14 Astrazeneca Ab Helicobacter pylori antigens
GB0010371D0 (en) * 2000-04-29 2000-06-14 Astrazeneca Ab Helicobacter pylori antigens
WO2012124764A1 (fr) * 2011-03-17 2012-09-20 国立大学法人三重大学 Procédé de production d'anticorps
BR112018012033A2 (pt) * 2015-12-14 2018-12-04 Max Planck Gesellschaft composição imunogênica e método para detectar infecção por h. pylori em um sujeito
CN115724922B (zh) * 2022-07-19 2023-08-22 四川大学华西医院 一种幽门螺杆菌疫苗重组蛋白抗原TonB及其制备方法与应用
CN115581201A (zh) * 2022-08-26 2023-01-10 云南省农业科学院花卉研究所 以茎段为外植体诱导的二倍体月季f1-61的植株再生方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994016714A1 (fr) * 1993-01-19 1994-08-04 Medicarb Ab COMPOSITION UTILISEE DANS LE TRAITEMENT D'INFECTIONS CAUSEES PAR $i(HELICOBACTER PYLORI)

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994016714A1 (fr) * 1993-01-19 1994-08-04 Medicarb Ab COMPOSITION UTILISEE DANS LE TRAITEMENT D'INFECTIONS CAUSEES PAR $i(HELICOBACTER PYLORI)

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL 31 January 1997 (1997-01-31), AKOPYANTS, N.S. ET AL.: "Helicobacter pylori cosmid clone 36, complete sequence", XP002303939, Database accession no. AC000108 *
DATABASE UniProt 1 January 1998 (1998-01-01), TOMB, J.-F. ET AL.: "Outer membrane protein (Omp11)", Database accession no. O25218 *
JEAN-F. TOMB ET AL.: "The complete genome sequence of the gastric pathogen Helicobacter pylori", NATURE, vol. 389, 25 September 1997 (1997-09-25), pages 539 - 547, XP002303938 *
SCHMITT W ET AL: "GENETIC ANALYSIS OF THE HELICOBACTER PYLORI VACUOLATING CYTOTOXIN: STRUCTURAL SIMILARITIES WITH THE IGA PROTEASE TYPE OF EXPORTED PROTEIN", MOLECULAR MICROBIOLOGY, BLACKWELL SCIENTIFIC, OXFORD, GB, vol. 12, no. 2, 1 April 1994 (1994-04-01), pages 307 - 319, XP000605827, ISSN: 0950-382X *
See also references of WO9818323A1 *

Also Published As

Publication number Publication date
KR20000052831A (ko) 2000-08-25
SK34699A3 (en) 2000-04-10
SA98180918A (ar) 2005-12-03
JP2001504329A (ja) 2001-04-03
PL333169A1 (en) 1999-11-22
BR9712587A (pt) 1999-10-26
NO991995D0 (no) 1999-04-27
WO1998018323A1 (fr) 1998-05-07
AU734052B2 (en) 2001-05-31
AU5093398A (en) 1998-05-22
AR009600A1 (es) 2000-04-26
NZ334568A (en) 2000-04-28
CA2265523A1 (fr) 1998-05-07
NO991995L (no) 1999-06-28
IL129397A0 (en) 2000-02-17
EP0973394A1 (fr) 2000-01-26
ID22065A (id) 1999-08-26
IS5005A (is) 1999-03-18
EE9900176A (et) 1999-12-15
TR199900940T2 (xx) 1999-09-21
CN1235513A (zh) 1999-11-17

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Free format text: NUCLEIC ACID AND AMINO ACID SEQUENCES RELATING TO HELICOBACTER PYLORI AND VACCINE COMPOSITIONS THEREOF

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