EP0930911A1 - Systeme de catheter - Google Patents

Systeme de catheter

Info

Publication number
EP0930911A1
EP0930911A1 EP98945182A EP98945182A EP0930911A1 EP 0930911 A1 EP0930911 A1 EP 0930911A1 EP 98945182 A EP98945182 A EP 98945182A EP 98945182 A EP98945182 A EP 98945182A EP 0930911 A1 EP0930911 A1 EP 0930911A1
Authority
EP
European Patent Office
Prior art keywords
catheter
lumen
catheter system
guide wire
pressure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP98945182A
Other languages
German (de)
English (en)
Other versions
EP0930911B1 (fr
Inventor
Ulrich Pfeiffer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pulsion Medical Systems SE
Original Assignee
Pulsion Verwaltungs GmbH and Co Medical Systems KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pulsion Verwaltungs GmbH and Co Medical Systems KG filed Critical Pulsion Verwaltungs GmbH and Co Medical Systems KG
Publication of EP0930911A1 publication Critical patent/EP0930911A1/fr
Application granted granted Critical
Publication of EP0930911B1 publication Critical patent/EP0930911B1/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0021—Catheters; Hollow probes characterised by the form of the tubing
    • A61M25/0023—Catheters; Hollow probes characterised by the form of the tubing by the form of the lumen, e.g. cross-section, variable diameter
    • A61M25/0026—Multi-lumen catheters with stationary elements
    • A61M25/003—Multi-lumen catheters with stationary elements characterized by features relating to least one lumen located at the distal part of the catheter, e.g. filters, plugs or valves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0021—Catheters; Hollow probes characterised by the form of the tubing
    • A61M25/0023—Catheters; Hollow probes characterised by the form of the tubing by the form of the lumen, e.g. cross-section, variable diameter
    • A61M25/0026—Multi-lumen catheters with stationary elements
    • A61M2025/0037—Multi-lumen catheters with stationary elements characterized by lumina being arranged side-by-side
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
    • A61M2025/0183—Rapid exchange or monorail catheters

Definitions

  • the present invention relates to a catheter system with a guide wire and with a catheter, in which a guide wire lumen is provided in the distal catheter tip area, which extends from the catheter tip to an opening provided laterally in the catheter tip area.
  • the catheters are usually inserted through a guide cannula that fills the lumen of the catheter and projects above it.
  • the arterial pressure is usually invasive by means of fluid coupling to an external pressure sensor measured. Blood gases and other physiological parameters are determined from blood samples taken through the lumen of the catheter.
  • the catheter in the vascular lumen leads to a reactive constriction of the radial artery and thus to a cessation of blood flow on the catheter, which also leads to incorrect pressure measurements (Mohr R., Lavee J., Goor DA (1987): Inaccuracy of radial artery pressure measurement after cardiac operations. J Thorac Cardiovascular Surg, 94 (2): 286-290). This incorrectly interpreted as arterial pressure arises by measuring a pulsating stagnant blood column.
  • Pressure curves in the radial artery generally differ strongly in shape, as well as in systolic and diastolic blood pressure, from pressure curves measured in central arteries, i.e. in the aorta (Gravlee GP, Brauer SD, O'Rourke MF, Avolio AP (1989 ): A comparison of brachial, femoral, and aortic intra-arterial pressures before and after cardiopulmonary bypass.Anesthetic Intensive Care, 17 (3):
  • Peripheral arterial pressure curves from the radial artery are also not to be used to calculate the stroke volume of the heart using the pulse contour method (Wesseling
  • the cardiac output and the circulatory filling state become in the perioperative
  • the area is usually determined via a pulmonary arterial thermodilution catheter (synonym: pulmonary artery catheter, pulmonary artery catheter) placed in addition to the arterial radialis catheter.
  • pulmonary arterial thermodilution a glucose or saline solution is injected in the central venous area, which has a temperature that differs from the blood temperature.
  • the pulmonary artery catheter At the distal end - placed in the pulmonary artery - the pulmonary artery catheter has a temperature sensor with which the thermodilution curve is registered.
  • the cardiac output is calculated from this thermodilution curve, for example using the Stewart-Hamilton method.
  • a pulmonary artery occlusion pressure is registered which is intended to provide information about the state of filling of the circle.
  • Cardiac output and circulatory fill status can also be measured using transcardiopulmonary arterial thermodilution (Pfeiffer U.J., Knoll R. (1993): Process for Determining a Patient's Circulatory Fill Status. United States
  • Patent No. 5,526,81 or also by means of thermal dye dilution (Pfeiffer UJ, Backus G., Blümel G., Eckart J., Müller P., Winkler P., Zeravik J., Zimmermann GJ (1990): A Fiberoptics-Based System for Integrated Monitoring of Cardiac Output, Intrathoracic Blood Volume. Extravascular Lung Water, 0 2 Saturation, and av Differences. Practical Applications of Fiberoptics in Critical Care Monitoring,
  • Thermo-dye dilution catheters with blood pressure lumens with a smallest diameter of 1.33 mm still do not allow reliable thermal or thermo-dye dilution measurements when the radial artery is punctured, since these can only be placed via an insertion catheter with a significantly larger outer diameter.
  • a radialis measurement is necessary because during many operations the anesthetist is unable to correct the position of a femoralis catheter or because there is no blood flow in the femoral artery as a result of the surgical procedure performed, or this is due to the influence of the Surgeons is adulterated.
  • thermo- or oximetry / thermo-dye Dilution catheters should be listed so that the sensors (fiber optic eye and thermistor) have so far been attached to the distal end and end flat at the end of the catheter next to the opening of the pressure lumen.
  • the sensors fiber optic eye and thermistor
  • an additional insertion catheter must always be used for the insertion of the measuring catheter, through which the measuring catheter is pushed into the blood vessel. Consequently, due to the larger diameter, this system results in a significantly larger puncture area and thus damage to the blood vessel wall and in a reduced blood flow.
  • the exposed fiber optic eye exposed at the tip of the catheter is often blind, since the tip of the catheter adheres to certain structures
  • Vascular wall such as ramifications, atherosclerotic changes, etc. are in contact or microthrombi formation can impair the function.
  • a catheter system of the type specified in the preamble of claim 1 is known.
  • This known catheter is preferably provided with a dilatation balloon, by means of which narrowed vessels, for example coronary arteries, can be expanded.
  • a catheter of this type is usually inserted through a lock attached to the femoral artery of the patient and advanced over the patient's aorta into the coronary system (cf. column 4, lines 8 and 9 of DE 42 00 030 C2).
  • Catheter is guided through the guidewire in the area of the catheter tip, the guidewire lying in the proximal area of the catheter adjoining the catheter tip, outside the catheter and parallel to it inside the blood vessel.
  • the guide wire thus serves to guide the catheter tip within the blood vessel system.
  • the insertion of such a catheter requires a comparatively large puncture area because of the need to use an insertion catheter or a sheath.
  • a large sterile surgical field is required, since the guidewire can easily come into contact with objects in the patient's environment during insertion.
  • EP 0 266 928 A1 describes a multifunctional cardiovascular catheter system is known, but in which the use of a guide wire is not provided.
  • the invention is based on the following tasks:
  • a new catheter system should be able to be placed quickly and easily in small blood vessels, for example in the radial artery, using direct, low-traumatizing guidewire technology.
  • the catheter should have a length that ensures that the sensor or sensors come to rest on the or in the catheter in a vascular area in which blood flow past the catheter is reliably ensured and in which - when placed in the arterial system - the Form of the blood pressure curve that comes very close in the aorta.
  • the guide wire used should be as short as possible.
  • the catheter should remain positionable and repositionable under sterile conditions.
  • catheter system of the type mentioned in the preamble of patent claim 1, in which catheter system the guide wire has a length which is substantially smaller than the length of the catheter.
  • the possibility is created, for example, of advancing the catheter into the vicinity of the aorta via a minimally traumatizing puncture of the radial artery, in order to carry out measurements there, for example blood pressure measurements or optical spectral measurements, which compared to previous measurements via the Puncture of the radial artery is far superior.
  • the new catheter system is used as follows: The radial artery is punctured using a cannula in the usual way. The short guide wire is then pushed over the lumen of the cannula into the blood vessel and the cannula is withdrawn while holding the guide wire. About the guide wire is by means of a
  • Dilator dilates the puncture site of the blood vessel.
  • the dilator is also withdrawn, leaving the guidewire in the vessel.
  • the guidewire is threaded into the distal opening in the catheter tip and the catheter is advanced so far that the guidewire protrudes from the lateral opening provided in the catheter tip area so far that it can be gripped safely with the fingers.
  • the catheter is pushed approximately 5 cm through the skin and subcutaneous tissue into the blood vessel using the guide wire.
  • the guide wire is drawn before the lateral opening of the guide wire lumen enters the blood vessel.
  • the catheter is then advanced (without guidewire) further to about 50 cm so that it reaches the tip of a large artery (e.g. the axillary artery).
  • a large artery e.g. the axillary artery.
  • the insertion of the catheter is minimally traumatic, since only the easily accessible radial artery has to be punctured and the use of a lock is not necessary. Thanks to the shortness of the guide wire, the sterile field can be kept very small without the risk of contamination of the guide wire during insertion.
  • the short guide wire provided according to the invention does not serve to guide the catheter within the blood vessel system, but rather only to insert the catheter through the puncture site into the blood vessel system.
  • the short guide wire provided according to the invention therefore replaces the lock or insertion cannula usually required for inserting catheters according to DE 42 00 030 C2.
  • the guide wire provided according to DE 42 00 030 C2 it therefore only has a formal shape
  • the guidewire according to DE 42 00 030 C2 has a length that is at least equal to the length of the catheter, since it serves to insert a catheter along the guidewire into small blood vessels, for example into the conor system to introduce (see column 4, paragraph 1 of DE 42 00 030 C2).
  • the dependent claims 2 to 10 relate to advantageous embodiments of the catheter system according to claim 1.
  • Figure 1 is a (greatly enlarged) longitudinal sectional view of a
  • Figure 2 is a cross-sectional view of the catheter system of Figure 1 along the
  • Figure 3 a channel division at the proximal end of the intravascular part of the
  • Figure 4 the channel division of the catheter system of Figure 1 with adhesive film and with a protective tube.
  • the catheter system according to the present invention illustrated by way of example with reference to FIGS. 1 to 4 has a usable intravascular length of approximately 50 cm and a length in normal-weight and normal-sized adult persons
  • Catheter shaft 1, 1 a is ideally made of low thrombogenic material such as polyurethane.
  • the catheter shaft 1, 1 a can have length markings and an X-ray contrast strip.
  • the catheter has a conically shaped guide wire lumen 8, through which a guide wire 10 can be pushed, which is significantly shorter than the entire catheter, that is to say approximately 20 cm in this example.
  • the guide wire lumen 8 leads about 5 cm after the tip through a laterally provided opening 9 back into the open. Through this opening 9, the guide wire 10 comes out again after the insertion.
  • the sensors for example fiber optic eye 4a and thermistor 5, 6, are attached proximally to this - sufficiently large - opening 9.
  • the flat surface of the fiber optic eye 4 a is arranged at an angle of less than ninety degrees to the catheter shaft 1, 1 a, whereby the light emission and the light reflection in or out of the blood flowing past the catheter is ensured.
  • heparinized rinsing solution continuously reaches the fiber optic eye 4a in order to avoid clot formation on the latter.
  • a pressure hose 12a, 12b Flanged to it - for example about 10 cm long channel extensions for the section 12a of a pressure hose 12a, 12b and for sensors 14, in this case a connection with fiber optic connector 20 and another connection with thermistor connector 21.
  • the section 12a of the pressure hose 12a, 12b opens into a three-way valve 13 flanged into the hose line with a lateral Luer lock
  • An additional pressure hose can be connected to this three-way valve 13 for easier zero point adjustment of a pressure sensor system.
  • Proximal to this three-way valve 13 is a further, about 10 cm long section 12b of the pressure hose 12a, 12b flanged, which directly to an electronic
  • Pressure transducer 15 is flanged with low compliance. Due to the fixed flange connections, air accumulations at the otherwise usual connectors are significantly reduced. The entire inner side of the pressure and blood sampling lumen 2 from the catheter to the pressure sensor 15 has an inner surface that is as smooth as possible.
  • a sterile, transparent and highly adhesive adhesive foil 22 (so-called protective tube adhesive foil 22) with an approximately 10 cm long integrated protective tube 23 is attached directly to the channel division 11 of the catheter. This is an optimal initial positioning as well
  • the short guide wire 10 of approximately 20 cm in length is an essential part of the catheter system.
  • This guidewire 10 has a diameter adapted to the short guidewire lumen 8 of the catheter. Included with this are a cannula with an inner diameter adapted to the guide wire 10 as well as a syringe and a so-called dilator which is approximately 5 cm long and approximately 1.3 mm in diameter.
  • the blood withdrawal / pressure measurement system of the catheter and the pressure hose 12a, 12b for the zero adjustment are filled with liquid (for example heparinized physiological
  • the radial artery is punctured in the usual way by means of a cannula.
  • the short guide wire 10 is then inserted into the blood vessel via the lumen of the cannula pushed and retracted the cannula while holding the guide wire 10 in the vessel.
  • the puncture side of the blood vessel is expanded via the guide wire 10 by means of the dilator.
  • the dilator is also withdrawn, leaving the guidewire 10 in the vessel. Then the guide wire 10 is threaded into the distal opening in the catheter tip and over the short
  • Guide wire lumens 8 advanced so far that the guide wire 10 has again emerged far enough from the lumen lying about 5 cm from the tip so that it can be gripped safely with the fingers.
  • the catheter with the guide wire 10 is about 5 cm through the skin and
  • Subcutaneous tissue is advanced into the blood vessel.
  • the guidewire 10 is pulled.
  • the catheter is then advanced further up to 50 cm until it comes to rest with the tip in a large artery (e.g. the axillary artery), which can also be recognized by the shape of the blood pressure curve registered simultaneously via the pressure and blood sampling lumen 2.
  • a large artery e.g. the axillary artery
  • the three-way valve 13 is opened to the atmosphere and brought to heart level by lifting the arm. If a zero point adjustment by lifting the arm is not possible, connecting a pressure hose of at least 50 cm length to the Luer lock connection of the three-way valve 13 will make one of the
  • the catheter system ensures the reliable detection of physiological or biochemical parameters by placing the sensors in the aortic region
  • the described exemplary embodiment of the catheter system according to the present invention enables aortic pressure measurement (Rulf et al, 1990; van Beck et al, 1993) and thus also the reliable evaluation of the pressure signal according to the pulse contour method, the reliable detection of transcardiopulmonary
  • Indicator dilution curves and continuous oxygen saturation measurement The principle can be extended to measure other parameters at any time.
  • the catheter can be introduced into peripheral arteries located near the surface by means of a short guide wire 10 and via a short guide wire lumen 8.
  • This safe and simple method eliminates the previously necessary Use of a catheter delivery system. With the same measuring catheter diameter, this enables the catheter to be inserted into smaller arteries, for example the radial artery.
  • this new short guidewire technique 10 the sterile field that must be created for insertion can be made significantly smaller than that used with conventional ones
  • the arrangement of the sensors set back from the tip of the catheter ensures that they can always be optimally placed in the flowing blood and are not disturbed in their function by certain vascular structures. Furthermore, direct flushing of the fiber optic eye 4a can be carried out via the opening 3 in the catheter shaft 1, 1a.
  • the direct flange-mounting of a pressure sensor 15 on the measuring catheter enables an optimal pressure measurement over a relatively thin pressure lumen, since the accumulation of air bubbles damping the pressure signal is avoided by the largely smooth inner surface of the pressure lumen up to the electrical pressure sensor 15.

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biophysics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)

Abstract

L'invention concerne un système de cathéter qui comprend un fil de guidage (10) et un cathéter. La zone distale de la pointe du cathéter comporte une lumière (8) destinée au fil de guidage, qui s'étend depuis la pointe du cathéter jusqu'à un orifice (9) disposé latéralement dans la zone de ladite pointe. La longueur du fil de guidage (10) est sensiblement inférieure à celle du cathéter.
EP98945182A 1997-08-07 1998-08-07 Systeme de catheter Expired - Lifetime EP0930911B1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19734220 1997-08-07
DE19734220A DE19734220C2 (de) 1997-08-07 1997-08-07 Kathetersystem mit einem Einführungsdraht
PCT/EP1998/005033 WO1999007429A1 (fr) 1997-08-07 1998-08-07 Systeme de catheter

Publications (2)

Publication Number Publication Date
EP0930911A1 true EP0930911A1 (fr) 1999-07-28
EP0930911B1 EP0930911B1 (fr) 2005-11-23

Family

ID=7838280

Family Applications (1)

Application Number Title Priority Date Filing Date
EP98945182A Expired - Lifetime EP0930911B1 (fr) 1997-08-07 1998-08-07 Systeme de catheter

Country Status (6)

Country Link
US (2) US6224585B1 (fr)
EP (1) EP0930911B1 (fr)
JP (1) JP3553088B2 (fr)
DE (2) DE19734220C2 (fr)
ES (1) ES2251100T3 (fr)
WO (1) WO1999007429A1 (fr)

Families Citing this family (79)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5911734A (en) * 1997-05-08 1999-06-15 Embol-X, Inc. Percutaneous catheter and guidewire having filter and medical device deployment capabilities
DE19734220C2 (de) * 1997-08-07 2000-01-13 Pulsion Verwaltungs Gmbh & Co Kathetersystem mit einem Einführungsdraht
US6328730B1 (en) * 1999-03-26 2001-12-11 William W. Harkrider, Jr. Endoluminal multi-luminal surgical sheath and method
IT1315206B1 (it) 1999-04-27 2003-02-03 Salvatore Romano Metodo e apparato per la misura della portata cardiaca.
US20040097996A1 (en) 1999-10-05 2004-05-20 Omnisonics Medical Technologies, Inc. Apparatus and method of removing occlusions using an ultrasonic medical device operating in a transverse mode
US6287291B1 (en) * 1999-11-09 2001-09-11 Advanced Cardiovascular Systems, Inc. Protective sheath for catheters
JP4656690B2 (ja) * 2000-04-27 2011-03-23 川澄化学工業株式会社 脈管用薬液注入カテーテル
EP1174076A3 (fr) 2000-07-18 2002-10-16 BIOTRONIK Mess- und Therapiegeräte GmbH & Co Ingenieurbüro Berlin Appareil permettant d'effectuer automatiquement une action diagnostique et/ou thérapeutique dans les cavités corporelles
US8579825B2 (en) * 2001-06-15 2013-11-12 Radi Medical Systems Ab Electrically conductive guide wire
US6702744B2 (en) 2001-06-20 2004-03-09 Advanced Cardiovascular Systems, Inc. Agents that stimulate therapeutic angiogenesis and techniques and devices that enable their delivery
US6814751B2 (en) 2001-10-12 2004-11-09 Rosengart Todd K Method and apparatus for performing an anastamosis
US7066953B2 (en) * 2001-10-12 2006-06-27 Rosengart Todd K Method and apparatus for performing an anastamosis
US8608661B1 (en) 2001-11-30 2013-12-17 Advanced Cardiovascular Systems, Inc. Method for intravascular delivery of a treatment agent beyond a blood vessel wall
US7018336B2 (en) * 2001-12-27 2006-03-28 Medtronic Minimed, Inc. Implantable sensor flush sleeve
US6979319B2 (en) * 2001-12-31 2005-12-27 Cardiac Pacemakers, Inc. Telescoping guide catheter with peel-away outer sheath
US7493156B2 (en) * 2002-01-07 2009-02-17 Cardiac Pacemakers, Inc. Steerable guide catheter with pre-shaped rotatable shaft
US6623436B2 (en) * 2002-02-20 2003-09-23 Transonic Systems, Inc. Retrograde catheter with reduced injectate induced temperature offset
US7361368B2 (en) 2002-06-28 2008-04-22 Advanced Cardiovascular Systems, Inc. Device and method for combining a treatment agent and a gel
DE10245416B4 (de) * 2002-09-28 2006-03-16 Pulsion Medical Systems Ag Kathetersystem mit besonderen Befestigungsmitteln
US7641643B2 (en) 2003-04-15 2010-01-05 Abbott Cardiovascular Systems Inc. Methods and compositions to treat myocardial conditions
US8821473B2 (en) 2003-04-15 2014-09-02 Abbott Cardiovascular Systems Inc. Methods and compositions to treat myocardial conditions
US8038991B1 (en) 2003-04-15 2011-10-18 Abbott Cardiovascular Systems Inc. High-viscosity hyaluronic acid compositions to treat myocardial conditions
US7128901B2 (en) 2003-06-04 2006-10-31 Colgate-Palmolive Company Extruded stick product and method for making same
US7740591B1 (en) * 2003-12-01 2010-06-22 Ric Investments, Llc Apparatus and method for monitoring pressure related changes in the extra-thoracic arterial circulatory system
US7220230B2 (en) * 2003-12-05 2007-05-22 Edwards Lifesciences Corporation Pressure-based system and method for determining cardiac stroke volume
US7422562B2 (en) * 2003-12-05 2008-09-09 Edwards Lifesciences Real-time measurement of ventricular stroke volume variations by continuous arterial pulse contour analysis
US7452333B2 (en) * 2003-12-05 2008-11-18 Edwards Lifesciences Corporation Arterial pressure-based, automatic determination of a cardiovascular parameter
US20050149096A1 (en) * 2003-12-23 2005-07-07 Hilal Said S. Catheter with conduit traversing tip
US7794414B2 (en) 2004-02-09 2010-09-14 Emigrant Bank, N.A. Apparatus and method for an ultrasonic medical device operating in torsional and transverse modes
US20050182387A1 (en) * 2004-02-13 2005-08-18 Cardiac Pacemakers, Inc. Peel-away catheter shaft
US7862811B2 (en) * 2004-02-27 2011-01-04 Regents Of The University Of Colorado Protease inhibition for prevention or treatment of heart failure
US7222539B2 (en) * 2004-06-04 2007-05-29 Radi Medical Systems Ab Sensor and guide wire assembly
EP1820531A4 (fr) * 2004-12-07 2008-04-23 Nipro Corp Catheter d'aspiration de thrombus dote d'une excellente capacite de passage
US20060263338A1 (en) * 2005-03-04 2006-11-23 Jacoby Douglas B Catheter-based delivery of Skeletal Myoblasts to the Myocardium of Damaged Hearts
US9539410B2 (en) 2005-04-19 2017-01-10 Abbott Cardiovascular Systems Inc. Methods and compositions for treating post-cardial infarction damage
US20080125745A1 (en) 2005-04-19 2008-05-29 Shubhayu Basu Methods and compositions for treating post-cardial infarction damage
US8187621B2 (en) 2005-04-19 2012-05-29 Advanced Cardiovascular Systems, Inc. Methods and compositions for treating post-myocardial infarction damage
US8828433B2 (en) 2005-04-19 2014-09-09 Advanced Cardiovascular Systems, Inc. Hydrogel bioscaffoldings and biomedical device coatings
US8303972B2 (en) 2005-04-19 2012-11-06 Advanced Cardiovascular Systems, Inc. Hydrogel bioscaffoldings and biomedical device coatings
US7732190B2 (en) 2006-07-31 2010-06-08 Advanced Cardiovascular Systems, Inc. Modified two-component gelation systems, methods of use and methods of manufacture
US9242005B1 (en) 2006-08-21 2016-01-26 Abbott Cardiovascular Systems Inc. Pro-healing agent formulation compositions, methods and treatments
US20080154186A1 (en) * 2006-11-07 2008-06-26 Angiodynamics, Inc. Multiple lumen catheter with proximal port
US8317773B2 (en) * 2006-11-07 2012-11-27 Angio Dynamics, Inc. Catheter with open faced sloped end portion
US8741326B2 (en) 2006-11-17 2014-06-03 Abbott Cardiovascular Systems Inc. Modified two-component gelation systems, methods of use and methods of manufacture
US9005672B2 (en) 2006-11-17 2015-04-14 Abbott Cardiovascular Systems Inc. Methods of modifying myocardial infarction expansion
US8192760B2 (en) 2006-12-04 2012-06-05 Abbott Cardiovascular Systems Inc. Methods and compositions for treating tissue using silk proteins
EP2166953B8 (fr) 2007-06-15 2018-11-07 Vivasure Medical Limited Dispositif de fermeture
ES2325715B1 (es) 2007-08-03 2010-06-17 Genetrix, S.L. Poblacion de celulas madre adultas derivadas de tejido adiposo cardiaco y su uso en regeneracion cardiaca.
US20090270739A1 (en) * 2008-01-30 2009-10-29 Edwards Lifesciences Corporation Real-time detection of vascular conditions of a subject using arterial pressure waveform analysis
DE102008009525A1 (de) * 2008-02-16 2009-08-27 Peter Osypka Stiftung Stiftung des bürgerlichen Rechts Vorrichtung zum Implantieren einer Verschlussvorrichtung im Herzen
US8968345B2 (en) * 2008-03-24 2015-03-03 Covidien Lp Surgical introducer with indicators
US20090326390A1 (en) * 2008-06-30 2009-12-31 Andres Belalcazar Pressure and Oxygen Saturation Monitoring Devices and Systems
EP2519161B1 (fr) 2009-12-30 2020-04-29 Vivasure Medical Limited Système de fermeture
US20130281761A1 (en) * 2010-11-05 2013-10-24 Tufts Medical Center, Inc. Cannula with bifurcated tip for a cardiac assist device
WO2012080783A1 (fr) 2010-12-15 2012-06-21 Querol Garcia Valeria Tube trilobulaire pour drainage
WO2012156819A2 (fr) * 2011-05-16 2012-11-22 Vivasure Medical Limited Système de dilatation de gaine et utilisations associées
ES2963543T3 (es) 2012-02-29 2024-03-27 Vivasure Medical Ltd Dispositivos de cierre de perforaciones percutáneas
US9345854B2 (en) 2012-11-26 2016-05-24 Lake Region Manufacturing, Inc. Distal shield for packaged guidewire
US9850013B2 (en) 2013-03-15 2017-12-26 Vivasure Medical Limited Loading devices and methods for percutaneous perforation closure systems
US10130269B2 (en) 2013-11-14 2018-11-20 Medtronic Vascular, Inc Dual lumen catheter for providing a vascular pressure measurement
US9877660B2 (en) 2013-11-14 2018-01-30 Medtronic Vascular Galway Systems and methods for determining fractional flow reserve without adenosine or other pharmalogical agent
US9913585B2 (en) 2014-01-15 2018-03-13 Medtronic Vascular, Inc. Catheter for providing vascular pressure measurements
EP3110317B1 (fr) 2014-02-25 2023-05-03 ICU Medical, Inc. Système de surveillance d'un patient avec signal gardien et procédé correspondant
US10973418B2 (en) 2014-06-16 2021-04-13 Medtronic Vascular, Inc. Microcatheter sensor design for minimizing profile and impact of wire strain on sensor
US10201284B2 (en) 2014-06-16 2019-02-12 Medtronic Vascular Inc. Pressure measuring catheter having reduced error from bending stresses
US11330989B2 (en) 2014-06-16 2022-05-17 Medtronic Vascular, Inc. Microcatheter sensor design for mounting sensor to minimize induced strain
US10194812B2 (en) 2014-12-12 2019-02-05 Medtronic Vascular, Inc. System and method of integrating a fractional flow reserve device with a conventional hemodynamic monitoring system
US10433826B2 (en) 2014-12-15 2019-10-08 Vivasure Medical Limited Closure apparatus with flexible sealable member and flexible support member
US11141142B2 (en) 2014-12-15 2021-10-12 Vivasure Medical Limited Implantable sealable member with mesh layer
CA2971512A1 (fr) 2014-12-23 2016-06-30 Mesoblast International Sarl Procede pour traiter l'insuffisance cardiaque
AU2016341195B2 (en) 2015-10-19 2019-03-14 Icu Medical, Inc. Hemodynamic monitoring system with detachable display unit
EP3389505A1 (fr) 2015-12-15 2018-10-24 Vivasure Medical Limited Appareil de fermeture d'artériotomie avec patin rainure pour distribution avantageuse de compression
US11272850B2 (en) 2016-08-09 2022-03-15 Medtronic Vascular, Inc. Catheter and method for calculating fractional flow reserve
US11330994B2 (en) 2017-03-08 2022-05-17 Medtronic Vascular, Inc. Reduced profile FFR catheter
US10646122B2 (en) 2017-04-28 2020-05-12 Medtronic Vascular, Inc. FFR catheter with covered distal pressure sensor and method of manufacture
US11235124B2 (en) 2017-08-09 2022-02-01 Medtronic Vascular, Inc. Collapsible catheter and method for calculating fractional flow reserve
US11219741B2 (en) 2017-08-09 2022-01-11 Medtronic Vascular, Inc. Collapsible catheter and method for calculating fractional flow reserve
US11185244B2 (en) 2018-08-13 2021-11-30 Medtronic Vascular, Inc. FFR catheter with suspended pressure sensor
WO2020157660A1 (fr) 2019-01-28 2020-08-06 Mesoblast International Sárl Procédé de traitement ou de prévention de l'hémorragie digestive

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3610228A (en) * 1967-01-06 1971-10-05 Birtcher Corp Apparatus for measuring body fluid pressure
US4718423A (en) 1986-10-17 1988-01-12 Spectramed, Inc. Multiple-function cardiovascular catheter system with very high lumenal efficiency and no crossovers
US5116317A (en) * 1988-06-16 1992-05-26 Optimed Technologies, Inc. Angioplasty catheter with integral fiber optic assembly
US5188634A (en) * 1990-07-13 1993-02-23 Trimedyne, Inc. Rotatable laser probe with beveled tip
US5217482A (en) * 1990-08-28 1993-06-08 Scimed Life Systems, Inc. Balloon catheter with distal guide wire lumen
US5271410A (en) 1991-04-01 1993-12-21 Baxter International Inc. Catheter with rapid response thermistor and method
US5976107A (en) * 1991-07-05 1999-11-02 Scimed Life Systems. Inc. Catheter having extendable guide wire lumen
US5222953A (en) 1991-10-02 1993-06-29 Kambiz Dowlatshahi Apparatus for interstitial laser therapy having an improved temperature sensor for tissue being treated
US5279573A (en) 1991-11-04 1994-01-18 Lake Region Manufacturing Company, Inc. Guidewire containment apparatus and method
DE4200030C2 (de) * 1992-01-02 1996-09-12 Eckhard Prof Dr Alt Katheter
JPH07509379A (ja) * 1992-01-09 1995-10-19 アドヴァンスド　カーディオヴァスキュラー　システムズ　インコーポレーテッド ガイドワイヤ交換装置
DE4214402C2 (de) 1992-04-30 1997-04-24 Pulsion Verwaltungs Gmbh & Co Vorrichtung zum Bestimmen des Füllungszustandes eines Blutkreislaufs
US5333609A (en) * 1992-05-19 1994-08-02 Minnesota Mining And Manufacturing Company Catheter and probe-catheter assembly
WO1994002077A2 (fr) 1992-07-15 1994-02-03 Angelase, Inc. Systeme de catheter pour ablation
US5823995A (en) * 1992-08-25 1998-10-20 Bard Connaught Dilatation catheter with stiffening wire anchored in the vicinity of the guide wire port
US5415639A (en) * 1993-04-08 1995-05-16 Scimed Life Systems, Inc. Sheath and method for intravascular treatment
US5921982A (en) 1993-07-30 1999-07-13 Lesh; Michael D. Systems and methods for ablating body tissue
US5728143A (en) 1995-08-15 1998-03-17 Rita Medical Systems, Inc. Multiple antenna ablation apparatus and method
US5443457A (en) * 1994-02-24 1995-08-22 Cardiovascular Imaging Systems, Incorporated Tracking tip for a short lumen rapid exchange catheter
US5902290A (en) * 1994-03-14 1999-05-11 Advanced Cardiovascular Systems, Inc. Catheter providing intraluminal access
US5853409A (en) 1994-06-27 1998-12-29 E.P. Technologies, Inc. Systems and apparatus for sensing temperature in body tissue
US5514092A (en) * 1994-08-08 1996-05-07 Schneider (Usa) Inc. Drug delivery and dilatation-drug delivery catheters in a rapid exchange configuration
AUPN775296A0 (en) * 1996-01-25 1996-02-22 Endogad Research Pty Limited Directional catheter
US6193685B1 (en) * 1996-11-26 2001-02-27 Schneider (Usa) Inc. Perfusion catheter
EP0884063B1 (fr) * 1997-06-10 2004-04-28 Schneider ( Europe) GmbH Système de cathéter
US5987995A (en) * 1997-07-17 1999-11-23 Sentec Corporation Fiber optic pressure catheter
DE19734220C2 (de) * 1997-08-07 2000-01-13 Pulsion Verwaltungs Gmbh & Co Kathetersystem mit einem Einführungsdraht

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See references of WO9907429A1 *

Also Published As

Publication number Publication date
DE19734220A1 (de) 1999-02-18
EP0930911B1 (fr) 2005-11-23
US6224585B1 (en) 2001-05-01
WO1999007429A1 (fr) 1999-02-18
JP2000514702A (ja) 2000-11-07
DE59813222D1 (de) 2005-12-29
DE19734220C2 (de) 2000-01-13
US6485481B1 (en) 2002-11-26
ES2251100T3 (es) 2006-04-16
JP3553088B2 (ja) 2004-08-11

Similar Documents

Publication Publication Date Title
EP0930911B1 (fr) Systeme de catheter
DE69938002T2 (de) Vorrichtung zum intravaskularen anbringen einer kanüle sowie anwendungsverfahren
EP1876948B1 (fr) Dispositif permettant l'acquisition de grandeurs de mesure physiologiques a l'interieur d'un corps
US4650472A (en) Apparatus and method for effecting percutaneous catheterization of a blood vessel using a small gauge introducer needle
US4033331A (en) Cardiac catheter and method of using same
DE60015439T2 (de) Kombiniertes Kathetersystem für eine intraaortale Blutpumpe und für die Bestimmung des Herzzeitvolumens mittels Thermodilution
DE3704500C2 (de) Mehrlumiger Ballonkatheter zum Messen des Herzausstoßes
DE4001760C2 (fr)
DE3714027C2 (fr)
DE60021300T2 (de) Geschlitzter Drainagekatheter mit Stylet
US6494846B1 (en) Dual-mode catheter
EP1402917B1 (fr) Cathéter avec fibre optique
DE4424267C2 (de) Vorrichtung zur kontinuierlichen Erfassung von Blutparametern
US20120136247A1 (en) Methods of Transvascular Retrograde Access Placement and Devices for Facilitating the Placement
EP0623356A1 (fr) Aiguille à double lumière pour retirer les liquides du corps
DE3715699A1 (de) Katheter und endoskop zur transpapillaeren darstellung der gallenblase
DE19738942A1 (de) Verfahren und Vorrichtung zur Injektionszeitpunkt- und Injektionsdauerbestimmung bei Thermodilutionsmessungen
CA2818600C (fr) Canule a autodilatation
US20190255298A1 (en) Slotted guidewire protector and advancing device and method
EP2185062B1 (fr) Ensemble cathéter à sonde optique et procédé pour appliquer une sonde optique dans un ensemble cathéter
EP0056103B1 (fr) Instrument de cathétérisme
EP2829226B1 (fr) Canule de perfusion à technique sensorielle intégrée
US4692155A (en) Catheter
DE102010053789A1 (de) Vorrichtung zur Durchführung physiologischer Messungen
CN215741227U (zh) 一种导管鞘及具有其的导管鞘组

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 19990108

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): BE DE ES FR GB IT NL SE

RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: PULSION MEDICAL SYSTEMS AG

17Q First examination report despatched

Effective date: 20020708

APBN Date of receipt of notice of appeal recorded

Free format text: ORIGINAL CODE: EPIDOSNNOA2E

APBR Date of receipt of statement of grounds of appeal recorded

Free format text: ORIGINAL CODE: EPIDOSNNOA3E

APBX Invitation to file observations in appeal sent

Free format text: ORIGINAL CODE: EPIDOSNOBA2E

APBZ Receipt of observations in appeal recorded

Free format text: ORIGINAL CODE: EPIDOSNOBA4E

APBT Appeal procedure closed

Free format text: ORIGINAL CODE: EPIDOSNNOA9E

GRAJ Information related to disapproval of communication of intention to grant by the applicant or resumption of examination proceedings by the epo deleted

Free format text: ORIGINAL CODE: EPIDOSDIGR1

GRAP Despatch of communication of intention to grant a patent

Free format text: ORIGINAL CODE: EPIDOSNIGR1

GRAS Grant fee paid

Free format text: ORIGINAL CODE: EPIDOSNIGR3

APAA Appeal reference recorded

Free format text: ORIGINAL CODE: EPIDOS REFN

APAF Appeal reference modified

Free format text: ORIGINAL CODE: EPIDOSCREFNE

GRAA (expected) grant

Free format text: ORIGINAL CODE: 0009210

AK Designated contracting states

Kind code of ref document: B1

Designated state(s): BE DE ES FR GB IT NL SE

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: NL

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20051123

REG Reference to a national code

Ref country code: GB

Ref legal event code: FG4D

Free format text: NOT ENGLISH

REF Corresponds to:

Ref document number: 59813222

Country of ref document: DE

Date of ref document: 20051229

Kind code of ref document: P

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: SE

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20060223

GBT Gb: translation of ep patent filed (gb section 77(6)(a)/1977)

Effective date: 20060227

REG Reference to a national code

Ref country code: ES

Ref legal event code: FG2A

Ref document number: 2251100

Country of ref document: ES

Kind code of ref document: T3

NLV1 Nl: lapsed or annulled due to failure to fulfill the requirements of art. 29p and 29m of the patents act
ET Fr: translation filed
PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: BE

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20060831

PLBE No opposition filed within time limit

Free format text: ORIGINAL CODE: 0009261

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: NO OPPOSITION FILED WITHIN TIME LIMIT

26N No opposition filed

Effective date: 20060824

BERE Be: lapsed

Owner name: PULSION MEDICAL SYSTEMS A.G.

Effective date: 20060831

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: ES

Payment date: 20080828

Year of fee payment: 11

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: IT

Payment date: 20080825

Year of fee payment: 11

Ref country code: FR

Payment date: 20080818

Year of fee payment: 11

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: GB

Payment date: 20080822

Year of fee payment: 11

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: DE

Payment date: 20081015

Year of fee payment: 11

GBPC Gb: european patent ceased through non-payment of renewal fee

Effective date: 20090807

REG Reference to a national code

Ref country code: FR

Ref legal event code: ST

Effective date: 20100430

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: FR

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20090831

Ref country code: DE

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20100302

REG Reference to a national code

Ref country code: ES

Ref legal event code: FD2A

Effective date: 20090808

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: GB

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20090807

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: IT

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20090807

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: ES

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20090808