EP0895475A4 - Antagonistes du recepteur de vitronectine - Google Patents
Antagonistes du recepteur de vitronectineInfo
- Publication number
- EP0895475A4 EP0895475A4 EP96945085A EP96945085A EP0895475A4 EP 0895475 A4 EP0895475 A4 EP 0895475A4 EP 96945085 A EP96945085 A EP 96945085A EP 96945085 A EP96945085 A EP 96945085A EP 0895475 A4 EP0895475 A4 EP 0895475A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- receptor antagonists
- vitronectin receptor
- vitronectin
- antagonists
- receptor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/73—Unsubstituted amino or imino radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pain & Pain Management (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US953295P | 1995-12-29 | 1995-12-29 | |
US9532P | 1995-12-29 | ||
PCT/US1996/020744 WO1997024122A1 (fr) | 1995-12-29 | 1996-12-20 | Antagonistes du recepteur de vitronectine |
Publications (2)
Publication Number | Publication Date |
---|---|
EP0895475A1 EP0895475A1 (fr) | 1999-02-10 |
EP0895475A4 true EP0895475A4 (fr) | 2000-08-23 |
Family
ID=21738237
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP96945085A Withdrawn EP0895475A4 (fr) | 1995-12-29 | 1996-12-20 | Antagonistes du recepteur de vitronectine |
Country Status (16)
Country | Link |
---|---|
EP (1) | EP0895475A4 (fr) |
JP (1) | JP2000502708A (fr) |
KR (1) | KR19990076876A (fr) |
CN (1) | CN1209060A (fr) |
AU (1) | AU1353897A (fr) |
BR (1) | BR9612378A (fr) |
CA (1) | CA2241724A1 (fr) |
CZ (1) | CZ203798A3 (fr) |
HU (1) | HUP9901116A2 (fr) |
IL (1) | IL125034A0 (fr) |
MX (1) | MX9805253A (fr) |
NO (1) | NO983002L (fr) |
PL (1) | PL327919A1 (fr) |
TR (1) | TR199801255T2 (fr) |
WO (1) | WO1997024122A1 (fr) |
ZA (1) | ZA9610855B (fr) |
Families Citing this family (40)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6008214A (en) * | 1994-08-22 | 1999-12-28 | Smithkline Beecham Corporation | Bicyclic compounds |
AU713676B2 (en) * | 1996-01-16 | 1999-12-09 | Merck & Co., Inc. | Integrin receptor antagonists |
JP2000508319A (ja) * | 1996-04-10 | 2000-07-04 | メルク エンド カンパニー インコーポレーテッド | αvβ3拮抗薬 |
US20030125317A1 (en) | 1996-10-02 | 2003-07-03 | Smithkline Beecham Corporation | Vitronectin receptor antagonists |
DE19653647A1 (de) | 1996-12-20 | 1998-06-25 | Hoechst Ag | Vitronectin - Rezeptorantagonisten, deren Herstellung sowie deren Verwendung |
DE19653645A1 (de) * | 1996-12-20 | 1998-06-25 | Hoechst Ag | Vitronectin - Rezeptorantagonisten, deren Herstellung sowie deren Verwendung |
US6482821B2 (en) | 1996-12-20 | 2002-11-19 | Hoechst Aktiengellschaft | Vitronectin receptor antagonists, their preparation and their use |
US6218387B1 (en) | 1996-12-20 | 2001-04-17 | Hoechst Aktiengesellschaft | Vitronectin receptor anatagonists, their preparation and their use |
US6239138B1 (en) * | 1997-07-25 | 2001-05-29 | Smithkline Beecham Corporation | Vitronectin receptor antagonist |
WO1999030709A1 (fr) * | 1997-12-17 | 1999-06-24 | Merck & Co., Inc. | Antagonistes du recepteur de l'integrine |
PL342881A1 (en) * | 1998-03-10 | 2001-07-16 | Smithkline Beecham Corp | Vitronectin receptor antagonists |
BR9909326A (pt) * | 1998-04-01 | 2000-12-12 | Janssen Pharmaceutica Nv | Derivados de piridina inibidores de pde iv |
GB9812088D0 (en) * | 1998-06-05 | 1998-08-05 | Celltech Therapeutics Ltd | Chemical compounds |
SE9803518D0 (sv) * | 1998-10-15 | 1998-10-15 | Astra Pharma Prod | Novel compounds |
CA2358855A1 (fr) | 1999-02-03 | 2000-08-10 | Merck & Co., Inc. | Derives de la benzazepine utilises comme antagonistes du recepteur alpha-v de l'integrine |
US6723711B2 (en) * | 1999-05-07 | 2004-04-20 | Texas Biotechnology Corporation | Propanoic acid derivatives that inhibit the binding of integrins to their receptors |
JP2003505416A (ja) | 1999-07-21 | 2003-02-12 | ワイス | αvβ3インテグリンに対して選択的な二環式拮抗薬 |
EG24179A (en) * | 1999-09-07 | 2008-09-28 | Smithkline Beecham Corp | Vitronectin receptor antagonists |
DE10028575A1 (de) | 2000-06-14 | 2002-03-14 | Basf Ag | Integrinliganden |
FR2800067B1 (fr) | 1999-10-21 | 2004-12-17 | Rhodia Chimie Sa | Intermediaires de fabrication d'un derive de type benzofurane ou benzothiophene nitre en position 5 et leurs utilisations |
FR2820743B1 (fr) | 2001-02-09 | 2005-02-25 | Pf Medicament | Procede et intermediaires de synthese pour la preparation de derives de pyridin-2-yl-methylamine |
PL363311A1 (en) | 2001-04-24 | 2004-11-15 | Merck Patent Gmbh | Combination therapy using anti-angiogenic agents and tnfalpha |
JP4800216B2 (ja) * | 2003-10-24 | 2011-10-26 | エグゼリクシス, インコーポレイテッド | p70S6キナーゼモジュレーターおよび使用方法 |
UA87854C2 (en) | 2004-06-07 | 2009-08-25 | Мерк Энд Ко., Инк. | N-(2-benzyl)-2-phenylbutanamides as androgen receptor modulators |
WO2006041046A1 (fr) * | 2004-10-13 | 2006-04-20 | Sankyo Company, Limited | Dérivé de pyridine |
MX2007013198A (es) | 2005-04-20 | 2008-03-24 | Johnson & Johnson | Moduladores de trombina de n-oxido de piridina fluorado y procedimiento para n-oxidacion de heteroarilos que contienen nitrogeno. |
JP2009523813A (ja) | 2006-01-18 | 2009-06-25 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング | 癌を治療するためにインテグリンのリガンドを使用する特異的な治療法 |
TW200811164A (en) * | 2006-05-12 | 2008-03-01 | Jerini Ag | New heterocyclic compounds for the inhibition of integrins and use thereof |
EA017864B1 (ru) | 2007-01-18 | 2013-03-29 | Мерк Патент Гмбх | Специфическая терапия и лекарственное средство на основе интегриновых лигандов для лечения рака |
EP2217238B1 (fr) | 2007-11-08 | 2014-03-12 | The General Hospital Corporation | Procédés et compositions pour le traitement de maladies protéinuriques |
EP2432779A1 (fr) | 2009-05-22 | 2012-03-28 | Exelixis, Inc. | Inhibiteurs de pi3k/mtor à base de benzoxazépines pour lutter contre les maladies prolifératives |
SG176103A1 (en) | 2009-05-25 | 2011-12-29 | Merck Patent Gmbh | Continuous administration of cilengitide in cancer treatments |
JP5791628B2 (ja) * | 2009-12-17 | 2015-10-07 | ビーエーエスエフ ソシエタス・ヨーロピアBasf Se | 高級エタノールアミンの製造方法 |
AU2010363329A1 (en) | 2010-11-07 | 2013-05-09 | Targegen, Inc. | Compositions and methods for treating myelofibrosis |
SG11201609050UA (en) | 2014-05-30 | 2016-12-29 | Pfizer | Carbonitrile derivatives as selective androgen receptor modulators |
EP3468953B1 (fr) | 2016-06-13 | 2024-05-22 | GlaxoSmithKline Intellectual Property Development Limited | Pyridines substituées utilisées en tant qu'inhibiteurs de dnmt1 |
US11046685B2 (en) | 2017-02-28 | 2021-06-29 | Morphic Therapeutic, Inc. | Inhibitors of (α-v)(β-6) integrin |
EP3589627A4 (fr) | 2017-02-28 | 2020-08-05 | Morphic Therapeutic, Inc. | Inhibiteurs de l'(alpha-v)(bêta-6) intégrine |
MX2021002181A (es) | 2018-08-29 | 2021-07-15 | Morphic Therapeutic Inc | Inhibicion de la integrina alfa v beta 6. |
WO2023275715A1 (fr) | 2021-06-30 | 2023-01-05 | Pfizer Inc. | Métabolites de modulateurs sélectifs du récepteur des androgènes |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1993000095A2 (fr) * | 1991-06-28 | 1993-01-07 | Smithkline Beecham Corporation | Antagonistes bicycliques de fibrinogene |
WO1994014776A2 (fr) * | 1992-12-21 | 1994-07-07 | Smithkline Beecham Corporation | Antagonistes bicycliques du fibrinogene |
WO1996000574A1 (fr) * | 1994-06-29 | 1996-01-11 | Smithkline Beecham Corporation | Antagonistes du recepteur de la vibronectine |
WO1997024336A2 (fr) * | 1995-12-29 | 1997-07-10 | Smithkline Beecham Plc | Procede d'aminocarbonilation de benzazepines et de benzodiazepines |
WO1997024124A1 (fr) * | 1995-12-29 | 1997-07-10 | Smithkline Beecham Corporation | Antagonistes du recepteur de la vitronectine |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3627754A (en) * | 1970-05-13 | 1971-12-14 | Hoffmann La Roche | Process for preparing 7-lower alkanoyl benzodiazepines utilizing ceric salts |
-
1996
- 1996-12-20 WO PCT/US1996/020744 patent/WO1997024122A1/fr not_active Application Discontinuation
- 1996-12-20 TR TR1998/01255T patent/TR199801255T2/xx unknown
- 1996-12-20 JP JP9524556A patent/JP2000502708A/ja active Pending
- 1996-12-20 CA CA002241724A patent/CA2241724A1/fr not_active Abandoned
- 1996-12-20 AU AU13538/97A patent/AU1353897A/en not_active Abandoned
- 1996-12-20 HU HU9901116A patent/HUP9901116A2/hu unknown
- 1996-12-20 KR KR1019980705003A patent/KR19990076876A/ko not_active Application Discontinuation
- 1996-12-20 CZ CZ982037A patent/CZ203798A3/cs unknown
- 1996-12-20 BR BR9612378A patent/BR9612378A/pt unknown
- 1996-12-20 PL PL96327919A patent/PL327919A1/xx unknown
- 1996-12-20 IL IL12503496A patent/IL125034A0/xx unknown
- 1996-12-20 EP EP96945085A patent/EP0895475A4/fr not_active Withdrawn
- 1996-12-20 CN CN96180099A patent/CN1209060A/zh active Pending
- 1996-12-23 ZA ZA9610855A patent/ZA9610855B/xx unknown
-
1998
- 1998-06-26 MX MX9805253A patent/MX9805253A/es unknown
- 1998-06-26 NO NO983002A patent/NO983002L/no not_active Application Discontinuation
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1993000095A2 (fr) * | 1991-06-28 | 1993-01-07 | Smithkline Beecham Corporation | Antagonistes bicycliques de fibrinogene |
WO1994014776A2 (fr) * | 1992-12-21 | 1994-07-07 | Smithkline Beecham Corporation | Antagonistes bicycliques du fibrinogene |
WO1996000574A1 (fr) * | 1994-06-29 | 1996-01-11 | Smithkline Beecham Corporation | Antagonistes du recepteur de la vibronectine |
WO1997024336A2 (fr) * | 1995-12-29 | 1997-07-10 | Smithkline Beecham Plc | Procede d'aminocarbonilation de benzazepines et de benzodiazepines |
WO1997024124A1 (fr) * | 1995-12-29 | 1997-07-10 | Smithkline Beecham Corporation | Antagonistes du recepteur de la vitronectine |
Non-Patent Citations (2)
Title |
---|
BONDINELL W E ET AL: "DESIGN OF A POTENT AND ORALLY ACTIVE NONPEPTIDE PLATELET FIBRINOGEN RECEPTOR (GPIIB/IIIA) ANTAGONIST", BIOORGANIC & MEDICINAL CHEMISTRY, GB, ELSEVIER SCIENCE LTD, vol. 2, no. 9, May 1994 (1994-05-01), pages 897 - 908, XP000196285, ISSN: 0968-0896 * |
See also references of WO9724122A1 * |
Also Published As
Publication number | Publication date |
---|---|
TR199801255T2 (xx) | 1998-10-21 |
AU1353897A (en) | 1997-07-28 |
NO983002D0 (no) | 1998-06-26 |
CA2241724A1 (fr) | 1997-07-10 |
KR19990076876A (ko) | 1999-10-25 |
CN1209060A (zh) | 1999-02-24 |
HUP9901116A2 (hu) | 2000-03-28 |
MX9805253A (es) | 1998-10-31 |
IL125034A0 (en) | 1999-01-26 |
PL327919A1 (en) | 1999-01-04 |
NO983002L (no) | 1998-08-26 |
EP0895475A1 (fr) | 1999-02-10 |
BR9612378A (pt) | 1999-07-13 |
WO1997024122A1 (fr) | 1997-07-10 |
JP2000502708A (ja) | 2000-03-07 |
CZ203798A3 (cs) | 1998-12-16 |
ZA9610855B (en) | 1997-11-24 |
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Legal Events
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