SG11201609050UA - Carbonitrile derivatives as selective androgen receptor modulators - Google Patents

Carbonitrile derivatives as selective androgen receptor modulators

Info

Publication number
SG11201609050UA
SG11201609050UA SG11201609050UA SG11201609050UA SG11201609050UA SG 11201609050U A SG11201609050U A SG 11201609050UA SG 11201609050U A SG11201609050U A SG 11201609050UA SG 11201609050U A SG11201609050U A SG 11201609050UA SG 11201609050U A SG11201609050U A SG 11201609050UA
Authority
SG
Singapore
Prior art keywords
androgen receptor
receptor modulators
selective androgen
carbonitrile derivatives
carbonitrile
Prior art date
Application number
SG11201609050UA
Inventor
Eugene Lvovich Piatnitski Chekler
Adam Matthew Gilbert
Rayomand Jal Unwalla
Patrick Robert Verhoest
James Thomas Anderson
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of SG11201609050UA publication Critical patent/SG11201609050UA/en

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    • A61K31/275—Nitriles; Isonitriles
    • A61K31/277—Nitriles; Isonitriles having a ring, e.g. verapamil
    • A—HUMAN NECESSITIES
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/402—1-aryl substituted, e.g. piretanide
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/433—Thidiazoles
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    • A61K31/451—Non condensed piperidines, e.g. piperocaine having a carbocyclic group directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine
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  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Rheumatology (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Obesity (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Dermatology (AREA)
  • Pulmonology (AREA)
  • Hospice & Palliative Care (AREA)
  • Reproductive Health (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Otolaryngology (AREA)
  • Immunology (AREA)
  • Emergency Medicine (AREA)
  • Psychiatry (AREA)
  • Nutrition Science (AREA)
  • Gastroenterology & Hepatology (AREA)
SG11201609050UA 2014-05-30 2015-05-18 Carbonitrile derivatives as selective androgen receptor modulators SG11201609050UA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462004979P 2014-05-30 2014-05-30
US201562149881P 2015-04-20 2015-04-20
PCT/IB2015/053658 WO2015181676A1 (en) 2014-05-30 2015-05-18 Carbonitrile derivatives as selective androgen receptor modulators

Publications (1)

Publication Number Publication Date
SG11201609050UA true SG11201609050UA (en) 2016-12-29

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SG11201609050UA SG11201609050UA (en) 2014-05-30 2015-05-18 Carbonitrile derivatives as selective androgen receptor modulators

Country Status (14)

Country Link
US (1) US10328082B2 (en)
EP (1) EP3148587B1 (en)
JP (2) JP6649902B2 (en)
KR (1) KR20160147007A (en)
CN (1) CN106572997A (en)
AU (2) AU2015265571A1 (en)
BR (1) BR112016027778A2 (en)
CA (1) CA2950390C (en)
ES (1) ES2864079T3 (en)
IL (1) IL249267A0 (en)
MX (1) MX2016015467A (en)
RU (1) RU2016146826A (en)
SG (1) SG11201609050UA (en)
WO (1) WO2015181676A1 (en)

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CN109937201A (en) 2016-09-15 2019-06-25 组装生物科学股份有限公司 Hepatitis B virus regulator
WO2018160878A1 (en) * 2017-03-02 2018-09-07 Assembly Biosciences, Inc. Cyclic sulfamide compounds and methods of using same
CN108362679A (en) * 2018-03-07 2018-08-03 厦门斯贝克科技有限责任公司 The resonance raman detection method of total amino acid content in a kind of quick detection herb liquid
SG11202107080VA (en) * 2019-01-11 2021-07-29 Naegis Pharmaceuticals Inc Leukotriene synthesis inhibitors
AU2020405091A1 (en) * 2019-12-18 2022-07-14 Curasen Therapeutics, Inc. Methods for improving neurological diseases and disorders
WO2021257940A1 (en) * 2020-06-18 2021-12-23 The Cleveland Clinic Foundation Treatment of viral infections with estrogen receptor modulators and anti-inflammatory agents
WO2022204235A1 (en) * 2021-03-23 2022-09-29 Nido Biosciences, Inc. Bicyclic compounds as androgen receptor modulators
WO2023275715A1 (en) * 2021-06-30 2023-01-05 Pfizer Inc. Metabolites of selective androgen receptor modulators

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