EP0759306A3 - Vorrichtung zum Verabreichen von Medikamenten - Google Patents

Vorrichtung zum Verabreichen von Medikamenten Download PDF

Info

Publication number
EP0759306A3
EP0759306A3 EP96112902A EP96112902A EP0759306A3 EP 0759306 A3 EP0759306 A3 EP 0759306A3 EP 96112902 A EP96112902 A EP 96112902A EP 96112902 A EP96112902 A EP 96112902A EP 0759306 A3 EP0759306 A3 EP 0759306A3
Authority
EP
European Patent Office
Prior art keywords
administering apparatus
medicine administering
medicine
administering
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP96112902A
Other languages
English (en)
French (fr)
Other versions
EP0759306B1 (de
EP0759306A2 (de
Inventor
Shigemi Nakamura
Kazunori Ishizeki
Hisatomo Ohki
Akira Yanagawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hitachi Unisia Automotive Ltd
Dott Co Ltd
Original Assignee
Dott Co Ltd
Unisia Jecs Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dott Co Ltd, Unisia Jecs Corp filed Critical Dott Co Ltd
Priority to EP01121188A priority Critical patent/EP1153626B1/de
Publication of EP0759306A2 publication Critical patent/EP0759306A2/de
Publication of EP0759306A3 publication Critical patent/EP0759306A3/de
Application granted granted Critical
Publication of EP0759306B1 publication Critical patent/EP0759306B1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0003—Details of inhalators; Constructional features thereof with means for dispensing more than one drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/062—Desiccants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
EP96112902A 1995-08-11 1996-08-09 Vorrichtung zum Verabreichen von Medikamenten Expired - Lifetime EP0759306B1 (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP01121188A EP1153626B1 (de) 1995-08-11 1996-08-09 Vorrichtung zum Verabreichen von Medikamenten

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP22726695A JP3317823B2 (ja) 1995-08-11 1995-08-11 投薬器
JP22726695 1995-08-11
JP227266/95 1995-08-11

Related Child Applications (1)

Application Number Title Priority Date Filing Date
EP01121188A Division EP1153626B1 (de) 1995-08-11 1996-08-09 Vorrichtung zum Verabreichen von Medikamenten

Publications (3)

Publication Number Publication Date
EP0759306A2 EP0759306A2 (de) 1997-02-26
EP0759306A3 true EP0759306A3 (de) 1997-05-28
EP0759306B1 EP0759306B1 (de) 2002-09-18

Family

ID=16858133

Family Applications (2)

Application Number Title Priority Date Filing Date
EP96112902A Expired - Lifetime EP0759306B1 (de) 1995-08-11 1996-08-09 Vorrichtung zum Verabreichen von Medikamenten
EP01121188A Expired - Lifetime EP1153626B1 (de) 1995-08-11 1996-08-09 Vorrichtung zum Verabreichen von Medikamenten

Family Applications After (1)

Application Number Title Priority Date Filing Date
EP01121188A Expired - Lifetime EP1153626B1 (de) 1995-08-11 1996-08-09 Vorrichtung zum Verabreichen von Medikamenten

Country Status (5)

Country Link
US (1) US5996577A (de)
EP (2) EP0759306B1 (de)
JP (1) JP3317823B2 (de)
DE (2) DE69633645T2 (de)
PT (2) PT1153626E (de)

Families Citing this family (63)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7131441B1 (en) 1995-12-07 2006-11-07 Skyepharma Ag Inhaler for multiple dosed administration of a pharmacological dry powder
PT995457E (pt) 1995-12-07 2004-07-30 Jago Res Ag Bocal para um inalador para a distribuicao reiterada doseadamente de um po farmacologicamente seco
JP3488620B2 (ja) 1998-02-05 2004-01-19 株式会社日立ユニシアオートモティブ 吸入式投薬器
SE9801114D0 (sv) * 1998-03-30 1998-03-30 Astra Ab Inhalation device
GB9827200D0 (en) * 1998-12-11 1999-02-03 Glaxo Group Ltd Dry powder inhaler
JP2000217917A (ja) 1999-01-27 2000-08-08 Unisia Jecs Corp 吸入式投薬器
FI990915A0 (fi) * 1999-04-23 1999-04-23 Orion Yhtymae Oyj Jauheinhalaattori
DE60019920T2 (de) * 1999-06-05 2006-02-23 Innovata Biomed Ltd., St. Albans Verabreichungsystem für medikamente
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
GB9920839D0 (en) * 1999-09-04 1999-11-10 Innovata Biomed Ltd Inhaler
WO2001041850A1 (en) * 1999-12-07 2001-06-14 Orion Corporation Multidose powder inhaler
DK1291031T3 (da) * 2000-06-12 2006-10-09 Teijin Ltd Multidosis-administrationsindretning til pulverformig medicin
JP2004512101A (ja) * 2000-10-20 2004-04-22 グラクソ　グループ　リミテッド 吸入器
US6595210B2 (en) 2000-11-27 2003-07-22 Unisia Jecs Corporation Inhalator for administering powder composition
GB0111336D0 (en) * 2001-05-10 2001-07-04 Innovata Biomed Ltd Device
EG24184A (en) * 2001-06-15 2008-10-08 Otsuka Pharma Co Ltd Dry powder inhalation system for transpulmonary
GB0128148D0 (en) 2001-11-23 2002-01-16 Innovata Biomed Ltd Assembly
US6923175B2 (en) * 2002-03-20 2005-08-02 Mannkind Corporation Inhalation apparatus
US7814900B2 (en) 2002-03-22 2010-10-19 Clinical Designs Limited Can fixture
US7284553B2 (en) * 2002-12-12 2007-10-23 Boehringer Ingelheim Pharma Gmbh & Co. Kg Powder inhaler comprising a chamber for a capsule for taking up a non-returnable capsule being filled with an active ingredient
GB0304000D0 (en) 2003-02-21 2003-03-26 Clinical Designs Ltd Dispenser
GB0327112D0 (en) 2003-11-21 2003-12-24 Clincial Designs Ltd Dispenser and reservoir
GB0328859D0 (en) 2003-12-12 2004-01-14 Clinical Designs Ltd Dispenser and counter
CA2562386C (en) 2004-04-21 2014-11-18 Innovata Biomed Limited Inhaler
GB0409197D0 (en) 2004-04-24 2004-05-26 Innovata Biomed Ltd Device
SE528190C2 (sv) 2004-06-07 2006-09-19 Mederio Ag Inhalator
AU2005251670B2 (en) * 2004-06-07 2010-04-22 Mederio Ag Securing dose quality of inhalable drug
DK1786784T3 (da) 2004-08-20 2011-02-14 Mannkind Corp Katalyse af diketopiperazinsyntese
EP2322180B1 (de) 2004-08-23 2015-05-27 MannKind Corporation Diketopiperazinsalze zur Arzneimitteldarreichung
JP2006130143A (ja) * 2004-11-08 2006-05-25 Hitachi Ltd 吸入式投薬器及び薬剤カートリッジ
GB0425518D0 (en) 2004-11-19 2004-12-22 Clinical Designs Ltd Substance source
GB0428204D0 (en) * 2004-12-23 2005-01-26 Clinical Designs Ltd Medicament container
GB0518400D0 (en) 2005-09-09 2005-10-19 Clinical Designs Ltd Dispenser
US7799344B2 (en) 2005-09-14 2010-09-21 Mannkind Corporation Method of drug formulation based on increasing the affinity of crystalline microparticle surfaces for active agents
DE102006007495A1 (de) * 2006-02-17 2007-08-23 Siegfried Generics International Ag Dispergiereinheit
ES2647080T3 (es) 2006-02-22 2017-12-19 Mannkind Corporation Un método para mejorar las propiedades farmacéuticas de micropartículas que comprenden dicetopiperazina y un agente activo
US20080142007A1 (en) * 2006-12-15 2008-06-19 Norton Healthcare Ltd Medicament dispenser for an inhaler
DE102007017725A1 (de) * 2007-04-16 2008-10-23 Astrazeneca Ab Inhalator für pulverförmige Substanzen
JP5081771B2 (ja) * 2007-11-09 2012-11-28 日立オートモティブシステムズ株式会社 粉末薬剤投与器
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
ES2929343T3 (es) 2008-06-13 2022-11-28 Mannkind Corp Inhalador de polvo seco accionado por aspiración para la administración de fármacos
EP2609954B1 (de) 2008-06-20 2021-12-29 MannKind Corporation Interaktives Gerät für die Echtzeit-Profilierung von Inhalationsversuchen
TWI494123B (zh) 2008-08-11 2015-08-01 Mannkind Corp 超快起作用胰島素之用途
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
GB0904059D0 (en) 2009-03-10 2009-04-22 Euro Celtique Sa Counter
GB0904040D0 (en) 2009-03-10 2009-04-22 Euro Celtique Sa Counter
CA2754595C (en) 2009-03-11 2017-06-27 Mannkind Corporation Apparatus, system and method for measuring resistance of an inhaler
AU2010259943C1 (en) 2009-06-12 2016-03-03 Mannkind Corporation Diketopiperazine microparticles with defined specific surface areas
CA2778698A1 (en) 2009-11-03 2011-05-12 Mannkind Corporation An apparatus and method for simulating inhalation efforts
CN102985125A (zh) 2010-06-21 2013-03-20 曼金德公司 干粉药物输送系统和方法
BR122020008875B8 (pt) 2011-04-01 2022-12-06 Mannkind Corp Embalagem de bolha e método de fabricação de uma embalagem de bolhas
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
AU2012328885B2 (en) 2011-10-24 2017-08-31 Mannkind Corporation Methods and compositions for treating pain
CN104114213B (zh) * 2011-12-16 2016-06-22 赛诺菲股份有限公司 通过吸入向病人施用粉末状药物的装置
EP2872205B1 (de) 2012-07-12 2017-02-08 MannKind Corporation System zur verabreichung von arzneimitteln in trockenpulverform
US10159644B2 (en) 2012-10-26 2018-12-25 Mannkind Corporation Inhalable vaccine compositions and methods
AU2014228415B2 (en) 2013-03-15 2018-08-09 Mannkind Corporation Microcrystalline diketopiperazine compositions and methods
BR112016000937A8 (pt) 2013-07-18 2021-06-22 Mannkind Corp formulações farmacêuticas de pó seco, método para a fabricação de uma formulação de pó seco e uso de uma formulação farmacêutica de pó seco
CN105517607A (zh) 2013-08-05 2016-04-20 曼金德公司 吹入设备和方法
WO2015148905A1 (en) 2014-03-28 2015-10-01 Mannkind Corporation Use of ultrarapid acting insulin
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
BR112018076760A2 (pt) * 2016-07-21 2019-03-26 Philip Morris Products Sa inalador de pó seco
CN112755473B (zh) * 2020-12-22 2021-12-17 中南大学湘雅医院 一种辅助吸药的呼吸内科肺功能康复理疗一体设备

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2587215A (en) * 1949-04-27 1952-02-26 Frank P Priestly Inhalator
GB2165159A (en) * 1984-10-04 1986-04-09 Orion Yhtymae Oy Dosing device
US5239993A (en) * 1992-08-26 1993-08-31 Glaxo Inc. Dosage inhalator providing optimized compound inhalation trajectory
EP0640354A2 (de) * 1990-09-26 1995-03-01 Pharmachemie B.V. Wirbelkammer-Pulverinhalator

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2581182A (en) * 1950-03-14 1952-01-01 Abbott Lab Inhaler
CY1492A (en) * 1981-07-08 1990-02-16 Draco Ab Powder inhalator
ZA837318B (en) 1982-10-08 1985-06-26 Glaxo Group Ltd Device for administering medicaments to patients
US4696356A (en) * 1985-01-02 1987-09-29 Ellion Dolores D Gun powder dispensing and measuring apparatus
US4811869A (en) * 1987-06-25 1989-03-14 Roger Tremblay Powder dispenser
JPH0779465B2 (ja) 1987-08-18 1995-08-23 日本放送協会 映像スクランブル伝送方式とその送受信装置
GB8804069D0 (en) * 1988-02-22 1988-03-23 Britains Petite Ltd Dispensers for powdered medication
FR2642676B1 (fr) * 1989-02-07 1991-06-21 Oreal Distributeur a piston pour produit pateux ou solide
SE466684B (sv) 1989-03-07 1992-03-23 Draco Ab Anordning vid en inhalator samt foerfarande foer att med anordningen registrera medicinering med inhalator
DE4004904A1 (de) * 1990-02-16 1990-09-13 Gerhard Brendel Trommel-applikator
DE4027391A1 (de) * 1990-08-30 1992-03-12 Boehringer Ingelheim Kg Treibgasfreies inhalationsgeraet
US5429122A (en) * 1990-09-26 1995-07-04 Zanen; Pieter Inhaler devices provided with a reservoir for several doses of medium for inhaling, transporting device, whirl chamber
FR2667509B1 (fr) * 1990-10-04 1995-08-25 Valois Inhalateur a poudre, dispositif de conditionnement de microdoses de poudre sous forme de bandes adaptees a etre utilisees dans un inhalateur a poudre, et procede de fabrication de ces bandes.
US5327883A (en) * 1991-05-20 1994-07-12 Dura Pharmaceuticals, Inc. Apparatus for aerosolizing powdered medicine and process and using
US5546932A (en) * 1992-03-25 1996-08-20 Tebro Sa Powder jet dispenser for medicament inhalation therapies
AU4829593A (en) * 1992-09-23 1994-04-12 Fisons Plc Inhalation device
IL108780A (en) * 1993-02-27 1999-06-20 Fisons Plc inhaler
GB9306703D0 (en) * 1993-03-31 1993-05-26 Fisons Plc Inhalation device
AU684779B2 (en) * 1993-05-12 1998-01-08 Teijin Limited Device and method for dispensing powdered medicine in multiple doses
US5349947A (en) * 1993-07-15 1994-09-27 Newhouse Michael T Dry powder inhaler and process that explosively discharges a dose of powder and gas from a soft plastic pillow
JP3545764B2 (ja) * 1993-08-18 2004-07-21 フアイソンズ・ピーエルシー 吸息率制御器を備えた吸入装置
US5524613A (en) * 1993-08-25 1996-06-11 Habley Medical Technology Corporation Controlled multi-pharmaceutical inhaler
DE4340768A1 (de) * 1993-11-30 1995-06-01 Bayer Ag Vorrichtung zum Inhalieren
JP3372105B2 (ja) * 1994-05-26 2003-01-27 株式会社日立ユニシアオートモティブ 吸入式投薬器
JP3388896B2 (ja) * 1994-08-08 2003-03-24 株式会社日立ユニシアオートモティブ 吸入式投薬器
US5901703A (en) * 1995-02-06 1999-05-11 Unisia Jecs Corporation Medicine administering device for nasal cavities
JP3320261B2 (ja) * 1995-06-01 2002-09-03 株式会社ユニシアジェックス 吸入式投薬器
JP3434396B2 (ja) * 1995-06-30 2003-08-04 株式会社日立ユニシアオートモティブ 鼻腔用投薬器
JP3317827B2 (ja) * 1995-10-09 2002-08-26 株式会社ユニシアジェックス 投薬器
JP3328132B2 (ja) * 1996-03-21 2002-09-24 株式会社ユニシアジェックス 吸入式投薬器
US5743251A (en) * 1996-05-15 1998-04-28 Philip Morris Incorporated Aerosol and a method and apparatus for generating an aerosol

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2587215A (en) * 1949-04-27 1952-02-26 Frank P Priestly Inhalator
GB2165159A (en) * 1984-10-04 1986-04-09 Orion Yhtymae Oy Dosing device
EP0640354A2 (de) * 1990-09-26 1995-03-01 Pharmachemie B.V. Wirbelkammer-Pulverinhalator
US5239993A (en) * 1992-08-26 1993-08-31 Glaxo Inc. Dosage inhalator providing optimized compound inhalation trajectory

Also Published As

Publication number Publication date
DE69623709T2 (de) 2003-01-30
JPH0951948A (ja) 1997-02-25
DE69633645T2 (de) 2005-10-20
EP1153626A1 (de) 2001-11-14
EP1153626B1 (de) 2004-10-13
DE69623709D1 (de) 2002-10-24
PT759306E (pt) 2003-01-31
DE69633645D1 (de) 2004-11-18
EP0759306B1 (de) 2002-09-18
EP0759306A2 (de) 1997-02-26
PT1153626E (pt) 2005-01-31
JP3317823B2 (ja) 2002-08-26
US5996577A (en) 1999-12-07

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