EP0652753A1 - Behandlung von dentoalveolären infektionen mit taurolidin und/oder taurultam - Google Patents

Behandlung von dentoalveolären infektionen mit taurolidin und/oder taurultam

Info

Publication number
EP0652753A1
EP0652753A1 EP93917947A EP93917947A EP0652753A1 EP 0652753 A1 EP0652753 A1 EP 0652753A1 EP 93917947 A EP93917947 A EP 93917947A EP 93917947 A EP93917947 A EP 93917947A EP 0652753 A1 EP0652753 A1 EP 0652753A1
Authority
EP
European Patent Office
Prior art keywords
taurolidine
dental
taurultam
infection
infections
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
EP93917947A
Other languages
English (en)
French (fr)
Inventor
Rolf Wilhelm Pfirrmann
Peter Geistlich
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ed Geistlich Soehne AG fuer Chemische Industrie
Original Assignee
Ed Geistlich Soehne AG fuer Chemische Industrie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ed Geistlich Soehne AG fuer Chemische Industrie filed Critical Ed Geistlich Soehne AG fuer Chemische Industrie
Publication of EP0652753A1 publication Critical patent/EP0652753A1/de
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Definitions

  • the present invention further provides an orally acceptable composition, said composition comprising taurolidine and/or taurultam together with pharmaceutically acceptable excipients in the form of a liquid gel, rinse solution or as an emulsion.
  • compositions according to the invention may be used either by themselves or in conjunction with surgery to combat the infection.

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
EP93917947A 1992-07-30 1993-07-29 Behandlung von dentoalveolären infektionen mit taurolidin und/oder taurultam Ceased EP0652753A1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB929216155A GB9216155D0 (en) 1992-07-30 1992-07-30 Treatment of dentoalveolar infections
GB9216155 1992-07-30
PCT/GB1993/001607 WO1994003174A1 (en) 1992-07-30 1993-07-29 Treatment of dentoalveolar infections with taurolidine and/or taurultam

Publications (1)

Publication Number Publication Date
EP0652753A1 true EP0652753A1 (de) 1995-05-17

Family

ID=10719520

Family Applications (1)

Application Number Title Priority Date Filing Date
EP93917947A Ceased EP0652753A1 (de) 1992-07-30 1993-07-29 Behandlung von dentoalveolären infektionen mit taurolidin und/oder taurultam

Country Status (5)

Country Link
EP (1) EP0652753A1 (de)
JP (1) JPH07509483A (de)
CA (1) CA2141056C (de)
GB (1) GB9216155D0 (de)
WO (1) WO1994003174A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100517210B1 (ko) * 1994-12-12 2006-06-07 오메로스 코포레이션 통증,염증및경련억제용관주용액
MX9703988A (es) * 1994-12-12 1998-02-28 Omeros Med Sys Inc SOLUCIaN Y MÉTODO DE IRRIGACIaN PARA LA INHIBICIaN DEL DOLOR, LA INFLAMACIaN Y ES ESPASMO.
BR9509985A (pt) * 1995-12-12 1998-11-03 Omeros Med Sys Inc Solução para irrigação e método para inibição de dor inflamação e esparmo
WO1997049383A1 (en) * 1996-06-24 1997-12-31 Bio-Safe Enterprises, Inc. Antibacterial composition
US5972933A (en) * 1998-01-08 1999-10-26 Ed. Geistlich Sohne Ag Fur Chemische Industrie Method of treating microbial infections
US6166007A (en) * 1998-07-02 2000-12-26 Sodemann; Klaus Antimicrobial locks comprising taurinamide derivatives and carboxylic acids and/or salts thereof
EP1797884B1 (de) * 1999-12-06 2013-09-11 Geistlich Pharma AG Taurolidin oder Taurultam zur Verwendung bei der Behandlung von Tumoren der Prostata, des Kolons, der Lungen und von wiederkehrendem Glioblastoma multiforme.
DE60030770T2 (de) * 1999-12-06 2007-09-06 Rhode Island Hospital Verwendung von taurolidin oder taurultam zur herstellung eines medikaments zur behandlung von ovarialkarzinomen
CN100519525C (zh) 1999-12-06 2009-07-29 葛兰素集团有限公司 芳香砜类及其医疗用途
JP5280603B2 (ja) 2001-10-01 2013-09-04 ガイストリッヒ ファーマ アーゲー 転移阻害のための方法
DE10261241A1 (de) * 2002-12-20 2004-07-15 3M Espe Ag Dentalmaterial mit bakteriostatischen und/oder bakteriziden Substanzen
DE60311958T2 (de) * 2003-02-03 2007-11-08 Polaschegg, Hans-Dietrich, Dr. Zusammensetzung zur Prävention von Infektionen durch subkutane Prothesen
WO2005115357A2 (en) * 2004-05-14 2005-12-08 Hans-Dietrich Polaschegg Taurolidine formulations and delivery
US7696182B2 (en) 2004-11-02 2010-04-13 Nd Partners, Llc Antimicrobial locking solutions comprising taurinamide derivatives and biologically acceptable salts and acids, with the addition of small concentrations of heparin
EP1787627A1 (de) 2005-11-17 2007-05-23 3M Innovative Properties Company Antimikrobielles Zahnabdruckmaterial
CA2812845A1 (en) * 2010-09-27 2012-04-05 Geistlich Pharma Ag Antimicrobial dental care preparation
CA3000868A1 (en) * 2015-10-07 2017-04-13 Cormedix Inc. Skin-penetrating formulation of taurolidine
US11738120B1 (en) 2022-04-14 2023-08-29 Cormedix Inc. Synthesis of taurolidine, purity profiles and polymorphs

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH600878A5 (de) * 1975-04-28 1978-06-30 Gaba Ag
GB1557163A (en) * 1975-06-24 1979-12-05 Geistlich Soehne Ag Dental care preparations
GB8328073D0 (en) * 1983-10-20 1983-11-23 Geistlich Soehne Ag Chemical compounds
DE69104608T2 (de) * 1991-07-04 1995-02-16 Weissenfluh Hawe Neos Pharmazeutische Zubereitungen, Clavulansäure enthaltend, für die Behandlung der Periodontitis.

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See references of WO9403174A1 *

Also Published As

Publication number Publication date
JPH07509483A (ja) 1995-10-19
GB9216155D0 (en) 1992-09-09
CA2141056C (en) 2005-02-15
CA2141056A1 (en) 1994-02-17
WO1994003174A1 (en) 1994-02-17

Similar Documents

Publication Publication Date Title
CA2141056C (en) Treatment of dentoalveolar infections with taurolidine and/or taurultam
AU716540B2 (en) New pharmaceutical composition with anaesthetic effect
KR101337578B1 (ko) 의료 장치 및 의약 제형에 유용한 점막 접착성 자일로글루칸 함유 제형
CN110996891B (zh) 包含氯己定的凝胶
EP0404558A1 (de) Flüssige Polymerzusammensetzung und Verfahren zu ihrer Verwendung
JP2022164947A (ja) 高張性抗微生物治療用組成物
US5902110A (en) Bone regeneration
PL209943B1 (pl) Zastosowanie moksifloksacyny stanowiącej kwas 1-cyklopropylo-6-fluoro-1,4-dihydro-8-metoksy-7-[(4aS,7aS)-oktahydro-6H-pirolo [3,4-b]pirydyn-6-ylo]-4-okso-3-chinolino-karboksylowy
US6488912B1 (en) Treatment of dentoalveolar infections with taurolidine and/or taurultam
AT15430U1 (de) Dentales Mittel auf Basis von Hyaluronan und Octenidindihydrochlorid
FR2618670A1 (fr) Preparation medicamenteuse a base d'huiles essentielles, ainsi que pate dentaire et gomme a macher la contenant
CA2173109A1 (en) Use of azithromycin for the treatment of adult periodontitis and topical compositions for this use
Alpan et al. Ozone in dentistry
RU2184538C2 (ru) Применение дихлорбензилового спирта для получения лекарственного средства для местного лечения воспаления и лекарственное средство, содержащее дихлорбензиловый спирт
Nariman et al. Clinical efficacy of hyaluronic acid in post-extraction sockets of impacted mandibular third molar
EP3914258B1 (de) Zusammensetzung zur behandlung von periodontitis und regeneration von interdentalpapillen
US20140303101A1 (en) Compositions for dental care
RU2809005C1 (ru) Средство для ухода за полостью рта, содержащее гексапептид и хлоргексидин
RU2330645C2 (ru) Способ лечения пародонтита
RU2761303C1 (ru) Способ получения фармацевтической композиции и фармацевтическая композиция для лечения и профилактики заболеваний пародонта
JP2895343B2 (ja) 咬合性外傷の治療剤
JPS62273910A (ja) 口腔用組成物
UA125272C2 (uk) Засіб у формі гелевої композиції "бензидафлазівердин" з пролонгованою дією для лікування захворювань тканин пародонта
Sood et al. Efficacy of biodegradable xanthan based chlorhezidine gel (Chlosite®) and 0.2% chlorhexidine irrigation following scaling and root planing for the treatment of chronic periodontitis
JPH0764732B2 (ja) 歯痛、歯髄炎治療剤

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 19950203

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE DE ES FR GB IT NL

17Q First examination report despatched

Effective date: 19950627

APAB Appeal dossier modified

Free format text: ORIGINAL CODE: EPIDOS NOAPE

APAB Appeal dossier modified

Free format text: ORIGINAL CODE: EPIDOS NOAPE

APAD Appeal reference recorded

Free format text: ORIGINAL CODE: EPIDOS REFNE

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION HAS BEEN REFUSED

18R Application refused

Effective date: 19981224

APAF Appeal reference modified

Free format text: ORIGINAL CODE: EPIDOSCREFNE