EP0590105B1 - Break-open phial - Google Patents

Break-open phial Download PDF

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Publication number
EP0590105B1
EP0590105B1 EP93902341A EP93902341A EP0590105B1 EP 0590105 B1 EP0590105 B1 EP 0590105B1 EP 93902341 A EP93902341 A EP 93902341A EP 93902341 A EP93902341 A EP 93902341A EP 0590105 B1 EP0590105 B1 EP 0590105B1
Authority
EP
European Patent Office
Prior art keywords
phial
extension
line
sleeve
axis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
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EP93902341A
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German (de)
French (fr)
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EP0590105A1 (en
Inventor
Gérard Joulia
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LOreal SA
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LOreal SA
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Publication date
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Publication of EP0590105A1 publication Critical patent/EP0590105A1/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/06Ampoules or carpules
    • A61J1/065Rigid ampoules, e.g. glass ampoules

Definitions

  • the present invention relates to a self-breaking bulb allowing easy flow of the product contained in the bulb.
  • self-breaking bulbs are glass bulbs comprising, in the vicinity of at least one of their ends, in a neck area of diameter smaller than that of the body of the bulb, a pre-baking line so that the user can break the bulb without a file, by exerting with the fingers a simple lateral pressure on the bulb, on both sides of the pre-baking line.
  • This pre-crushing line can be obtained by numerous methods such as filing, localized deposition of an enamel on the glass, localized heating or the like.
  • the diameter at the pre-crushing line is limited by the possibility of manually breaking the bulb. In practice, this diameter cannot exceed approximately 8 mm. Under these conditions, one cannot obtain an opening allowing the free flow of the product as with a bottle. Consequently, the flow of the fluid contained in the ampoules is often difficult and the user is led to vigorously shake the ampoule to empty it.
  • FR-A 2 542 284 it is known from FR-A 2 542 284 to deposit by spraying or coating, at the level of the pre-baking line, a polymer coating having a thickness of a few tenths of a millimeter, to avoid injuring the user by possible shards of glass produced when the bulb broke. It is also known from EP-A-0 269 003 to cover the neck area of a bulb with a sleeve which, after breaking the bulb, forms an umbrella on the broken end of the bulb capable of retaining any shards of glass produced during breaking. These devices do not in any way improve the distribution of the liquid product contained in the ampoule.
  • the problem of the flow of the product can be solved by fitting a plastic sleeve which forms, after the ampoule neck area, at the level of the pre-baking line. breaking and eliminating the broken end, an extension of the neck area projecting beyond the broken edge of the bulb.
  • the present invention therefore relates to a self-breaking bulb whose body contains a fluid product and which is provided, in the vicinity of one of its ends, with a neck of revolution zone around an axis, a pre-baking line being formed on said neck area, characterized in that said neck area is covered, at the level of the pre-crushing line, with a sleeve of plastic material projecting, over at least one angular sector, beyond the line of pre-crushing on the side opposite the body, forming, after breaking the bulb along the pre-crushing line, an extension, the projection of which on the axis has a length at least equal to 20% of the diameter of the orifice defined by the edge of the part of the neck remaining adjacent to the body, the plane tangent to the surface forming said extension in the vicinity of the pre-crushing line forming with the axis of the neck zone an angle alpha less than 60 °.
  • the alpha angle is preferably between 40 and 50 °.
  • the plastic sleeve is preferably made of heat-shrinkable plastic material.
  • the heat-shrinkable plastic material can, in known manner, consist of a polyolefin, a fluorinated plastic such as polyvinylidene fluoride or tetrafluoroethylene, elastomers such as fluoelastomers and silicones having shrinkage temperatures of the order of 90 ° at 100 ° C.
  • the heat-shrinkable sleeve preferably has a thickness of between 0.04 and 0.5 mm.
  • the extension is preferably formed all around the axis of the neck area over an angular sector of 360 °.
  • the free edge of the extension is advantageously substantially in a plane perpendicular to the axis of the neck.
  • the plastic sleeve can have any length on the side opposite the extension: it can, in particular, cover most of the bulb and serve as a label.
  • the presence of the extension on the bulb according to the invention also has the advantage of preventing the formation of shards of glass when the end of the bulb is broken.
  • the presence of the extension prevents the user from injuring himself with the edge of the neck after breaking.
  • the bulb shown in Figure 1 is a glass bulb type "bottle", which is designated as a whole by the reference 1.
  • the bulb 1 is of revolution around a longitudinal axis XX; it comprises a cylindrical body 3, in which is contained a fluid product P.
  • the body 3 is closed, at one of its ends along the axis XX, by a concave bottom 2; the other end is formed by a neck area 4 of diameter smaller than that of the body 3 and connected to the latter by a shoulder 5.
  • the neck zone 4 is constituted by a cylindrical part 6 connected to an annular zone of smaller diameter than the cylindrical part 6, on which a pre-pressing line 7 has been provided, for example by filing.
  • a pre-pressing line 7 On the side opposite to the part 6, the annular zone is attached to a bulb 8, the tip 9 of which has been closed by welding after filling of the body 3 of the bulb.
  • a sleeve 10 made of heat-shrinkable plastic surrounds the cylindrical part 6 of the neck, the annular zone on which the pre-crushing line 7 is engraved and part of the bulb 8.
  • This plastic sleeve was placed on the neck zone 4 by placing on the shoulder 5 a section of cylindrical tube formed of a sheet of heat-shrinkable polyester having a thickness of 0.04 mm, and by heating it to 90 ° C so as to form a sleeve 10, which fits tightly, without stick on the neck area 4.
  • the outside diameter of the neck area 4 at the level of the pre-pressing line 7 is 6 mm and the distance d (measured in projection on the axis XX) between the pre-pressing line 7 and the edge of the sleeve 10 on the bulb. 8 is approximately 2 mm.
  • the thickness e of the glass constituting the bulb is approximately 0.7 mm.
  • the viscosity of the product is 45 centipoise and its surface tension is 30 x 10 ⁇ 4 N / m (30 Dyn / cm).

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  • Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Details Of Rigid Or Semi-Rigid Containers (AREA)
  • Disintegrating Or Milling (AREA)

Abstract

A break-open phial (1) of the ''bottle'' type is disclosed, providing for the easy flow of the product held in the phial. The neck area (4) of the phial is covered with a plastic (preferably heat shrinkable) sleeve (10) at its break line (7), with an extension in the form of a tab or collar extending beyond the break line (7) after breaking of the phial along said line (7). The length d^_ of this extension (10a^_) (measured as a projection onto the neck area centreline) is at least 20 % of the diameter of the opening which results from breaking the phial along line (7). The plane at a tangent to the surface forming the said extension (10b^_) proximate to line (7) makes an angle of less than 60° with the line X-X.

Description

La présente invention concerne une ampoule autocassable permettant un écoulement facile du produit contenu dans l'ampoule.The present invention relates to a self-breaking bulb allowing easy flow of the product contained in the bulb.

De façon connue les ampoules autocassables sont des ampoules en verre comportant au voisinage d'au moins une de leurs extrémités, dans une zone de goulot de diamètre plus faible que celui du corps de l'ampoule, une ligne de précassage de façon que l'utilisateur puisse casser l'ampoule sans lime, en exerçant avec les doigts une simple pression latérale sur l'ampoule, de part et d'autre de la ligne de précassage. Cette ligne de précassage peut être obtenue par de nombreux procédés tels que limage, dépôt localisé d'un émail sur le verre, chauffage localisé ou autre.In known manner, self-breaking bulbs are glass bulbs comprising, in the vicinity of at least one of their ends, in a neck area of diameter smaller than that of the body of the bulb, a pre-baking line so that the user can break the bulb without a file, by exerting with the fingers a simple lateral pressure on the bulb, on both sides of the pre-baking line. This pre-crushing line can be obtained by numerous methods such as filing, localized deposition of an enamel on the glass, localized heating or the like.

Le diamètre au niveau de la ligne de précassage est limité par la possibilité de casser manuellement l'ampoule. Pratiquement ce diamètre ne peut pas dépasser environ 8 mm. Dans ces conditions, on ne peut pas obtenir une ouverture permettant l'écoulement libre du produit comme avec une bouteille. Par conséquent, l'écoulement du produit fluide contenu dans les ampoules est souvent difficile et l'utilisateur est amené à secouer vigoureusement l'ampoule pour la vider.The diameter at the pre-crushing line is limited by the possibility of manually breaking the bulb. In practice, this diameter cannot exceed approximately 8 mm. Under these conditions, one cannot obtain an opening allowing the free flow of the product as with a bottle. Consequently, the flow of the fluid contained in the ampoules is often difficult and the user is led to vigorously shake the ampoule to empty it.

Pour améliorer l'écoulement du produit, il est connu d'ouvrir l'ampoule à ses deux extrémités. Mais ce procédé limite les formes d'ampoules utilisables ; en effet l'ampoule doit comporter deux goulots ou deux pointes. De plus, il est nécessaire d'utiliser en une fois la totalité de la dose de produit contenue dans l'ampoule.To improve the flow of the product, it is known to open the ampoule at its two ends. But this process limits the forms of usable bulbs; indeed the bulb must have two necks or two points. In addition, it is necessary to use at once the entire dose of product contained in the ampoule.

On a également proposé d'enfiler, sur la zone de goulot, après cassage, un petit embout distributeur en matériau souple, ayant la forme d'un doigt de gant, comportant à son extrémité un petit orifice de distribution. En appuyant de façon répétée sur cet embout, celui-ci fait office de pompe et permet de distribuer le produit. Mais cet embout est relativement coûteux et les boîtes d'ampoules ne comportent donc qu'un seul embout : celui-ci peut facilement être égaré et il n'est alors plus possible de distribuer aisément le produit contenu dans les ampoules restantes.It has also been proposed to thread, over the neck area, after breaking, a small dispensing nozzle made of flexible material, having the shape of a thermowell, comprising at its end a small dispensing orifice. By pressing repeatedly on this nozzle, it acts as a pump and allows the product to be dispensed. But this tip is relatively expensive and the ampoule boxes therefore have only one tip: it can easily be lost and it is then no longer possible to easily distribute the product contained in the remaining ampoules.

On cherche donc à fabriquer des ampoules autocassables de type "bouteille", que l'on n'ouvre qu'à une seule extrémité, de façon à pouvoir leur donner des formes multiples, et dont le produit puisse néanmoins s'écouler librement, pour ne pas être obligé d'utiliser en une fois la totalité de la dose contenue dans l'ampoule. En outre, on désire éviter l'adjonction d'un embout après que l'ampoule ait été ouverte.We therefore seek to manufacture self-breaking bulbs of the "bottle" type, which we open only at one end, so that we can give them multiple shapes, and the product of which can nevertheless flow freely, to not be forced to use in one times the entire dose in the vial. In addition, it is desired to avoid the addition of a tip after the bulb has been opened.

Par ailleurs, il est connu par FR-A 2 542 284 de déposer par pulvérisation ou enduction, au niveau de la ligne de précassage un revêtement de polymère ayant une épaisseur de quelques dixièmes de millimètre, pour éviter de blesser l'utilisateur par les éventuels éclats de verre produits au moment du cassage de l' ampoule. Il est également connu par EP-A-0 269 003 de recouvrir la zone de goulot d'une ampoule d'un manchon qui, après cassage de l'ampoule, forme sur l'embout cassé de l'ampoule une ombrelle susceptible de retenir les éventuels éclats de verre produits au moment du cassage. Ces dispositifs ne permettent aucunement d'améliorer la distribution du produit liquide contenu dans l'ampoule.Furthermore, it is known from FR-A 2 542 284 to deposit by spraying or coating, at the level of the pre-baking line, a polymer coating having a thickness of a few tenths of a millimeter, to avoid injuring the user by possible shards of glass produced when the bulb broke. It is also known from EP-A-0 269 003 to cover the neck area of a bulb with a sleeve which, after breaking the bulb, forms an umbrella on the broken end of the bulb capable of retaining any shards of glass produced during breaking. These devices do not in any way improve the distribution of the liquid product contained in the ampoule.

Il est également connu par FR-A-941 772 d'introduire de façon étanche un entonnoir dans le goulot d'une bouteille pour éviter l'écoulement de gouttes de liquide sur la paroi externe du goulot.It is also known from FR-A-941 772 to tightly introduce a funnel into the neck of a bottle to prevent the flow of drops of liquid on the external wall of the neck.

Selon la présente invention, on a trouvé que l'on peut résoudre le problème de l'écoulement du produit en ajustant sur la zone de goulot de l'ampoule, au niveau de la ligne de précassage, un manchon en plastique qui forme, après cassage et élimination de l'extrémité cassée, un prolongement de la zone de goulot faisant saillie au-delà du bord cassé de l'ampoule.According to the present invention, it has been found that the problem of the flow of the product can be solved by fitting a plastic sleeve which forms, after the ampoule neck area, at the level of the pre-baking line. breaking and eliminating the broken end, an extension of the neck area projecting beyond the broken edge of the bulb.

La présente invention a donc pour objet une ampoule autocassable dont le corps contient un produit fluide et qui est munie, au voisinage d'une de ses extrémités, d'une zone de goulot de révolution autour d'un axe, une ligne de précassage étant ménagée sur ladite zone de goulot, caractérisée par le fait que ladite zone de goulot est recouverte, au niveau de la ligne de précassage, d'un manchon en matériau plastique dépassant, sur au moins un secteur angulaire, au-delà de la ligne de précassage du côté opposé au corps en formant, après cassage de l'ampoule selon la ligne de précassage, un prolongement, dont la projection sur l'axe a une longueur au moins égale à 20 % du diamètre de l'orifice défini par le bord de la partie du goulot restant attenante au corps, le plan tangent à la surface formant ledit prolongement au voisinage de la ligne de précassage faisant avec l'axe de la zone de goulot un angle alpha inférieur à 60°. L'angle alpha est, de préférence, compris entre 40 et 50°.The present invention therefore relates to a self-breaking bulb whose body contains a fluid product and which is provided, in the vicinity of one of its ends, with a neck of revolution zone around an axis, a pre-baking line being formed on said neck area, characterized in that said neck area is covered, at the level of the pre-crushing line, with a sleeve of plastic material projecting, over at least one angular sector, beyond the line of pre-crushing on the side opposite the body, forming, after breaking the bulb along the pre-crushing line, an extension, the projection of which on the axis has a length at least equal to 20% of the diameter of the orifice defined by the edge of the part of the neck remaining adjacent to the body, the plane tangent to the surface forming said extension in the vicinity of the pre-crushing line forming with the axis of the neck zone an angle alpha less than 60 °. The alpha angle is preferably between 40 and 50 °.

Selon l'invention le manchon en plastique est, de préférence, en matériau plastique thermorétractable. De cette façon le manchon en plastique s'adapte étroitement à la forme de la zone de goulot de l'ampoule par simple chauffage. Le matériau plastique thermorétractable peut, de façon connue, être constitué par une polyoléfine, un plastique fluoré tel que le fluorure de polyvinylidène ou le tétrafluoroéthylène, des élastomères tels que des fluoélastomères et des silicones ayant des températures de rétreint de l'ordre de 90° à 100° C. Le manchon thermorétractable a, de préférence une épaisseur comprise entre 0,04 et 0,5 mm.According to the invention, the plastic sleeve is preferably made of heat-shrinkable plastic material. In this way the plastic sleeve adapts tightly to the shape of the bulb neck area by simple heating. The heat-shrinkable plastic material can, in known manner, consist of a polyolefin, a fluorinated plastic such as polyvinylidene fluoride or tetrafluoroethylene, elastomers such as fluoelastomers and silicones having shrinkage temperatures of the order of 90 ° at 100 ° C. The heat-shrinkable sleeve preferably has a thickness of between 0.04 and 0.5 mm.

Le prolongement est, de préférence, ménagé tout autour de l'axe de la zone de goulot sur un secteur angulaire de 360°. Le bord libre du prolongement est avantageusement sensiblement dans un plan perpendiculaire à l'axe du goulot. Le manchon en plastique peut avoir, du côté opposé au prolongement, une longueur quelconque : il peut, en particulier, recouvrir la majeure partie de l'ampoule et servir d'étiquette.The extension is preferably formed all around the axis of the neck area over an angular sector of 360 °. The free edge of the extension is advantageously substantially in a plane perpendicular to the axis of the neck. The plastic sleeve can have any length on the side opposite the extension: it can, in particular, cover most of the bulb and serve as a label.

On a constaté que la présence du prolongement sur le bord du goulot permet de provoquer l'écoulement du produit, alors qu'en l'absence de prolongement, l'écoulement ne se produit pas. Ce phénomène n'est pas expliqué et il est probable qu'il est fonction de plusieurs paramètres. Ce phénomène pourrait par exemple être dû, en partie, à la différence de mouillabilité entre le verre et le matériau plastique. On peut également émettre l'hypothèse qu'il est partiellement dû à un effet de cavitation provoqué par le décrochement entre la paroi de verre et la paroi plastique correspondant à l'épaisseur du verre.It has been found that the presence of the extension on the edge of the neck makes it possible to cause the product to flow, while in the absence of an extension, the flow does not occur. This phenomenon is not explained and it is likely that it is a function of several parameters. This phenomenon could for example be due, in part, to the difference in wettability between the glass and the plastic material. It can also be hypothesized that it is partially due to a cavitation effect caused by the drop between the glass wall and the plastic wall corresponding to the thickness of the glass.

La présence du prolongement sur l'ampoule selon l'invention a également pour avantage d'empêcher la formation d'éclats de verre lors du cassage de l'extrémité de l'ampoule. En outre, la présence du prolongement empêche l'utilisateur de se blesser avec le bord du goulot après cassage.The presence of the extension on the bulb according to the invention also has the advantage of preventing the formation of shards of glass when the end of the bulb is broken. In addition, the presence of the extension prevents the user from injuring himself with the edge of the neck after breaking.

La description donnée ci-après, à titre purement illustratif et non limitatif, d'un mode de réalisation de l'invention, ainsi que le dessin annexé, permettront de mieux comprendre l'invention.The description given below, purely by way of non-limiting illustration, of an embodiment of the invention, as well as the appended drawing, will allow a better understanding of the invention.

Sur ce dessin :

  • la figure 1 représente, vue en élévation, une ampoule selon l'invention avant cassage ; et
  • la figure 2 représente la même ampoule après cassage.
On this drawing :
  • Figure 1 shows, in elevation, a bulb according to the invention before breaking; and
  • Figure 2 shows the same bulb after breaking.

L'ampoule représentée sur la figure 1 est une ampoule en verre de type "bouteille", qui est désignée dans son ensemble par la référence 1. L'ampoule 1 est de révolution autour d'un axe longitudinal X-X ; elle comporte un corps cylindrique 3, dans lequel est contenu un produit fluide P. Le corps 3 est fermé, à l'une de ses extrémités selon l'axe X-X, par un fond 2 concave ; l'autre extrémité est constituée par une zone de goulot 4 de diamètre inférieur à celui du corps 3 et se rattachant à celui-ci par un épaulement 5.The bulb shown in Figure 1 is a glass bulb type "bottle", which is designated as a whole by the reference 1. The bulb 1 is of revolution around a longitudinal axis XX; it comprises a cylindrical body 3, in which is contained a fluid product P. The body 3 is closed, at one of its ends along the axis XX, by a concave bottom 2; the other end is formed by a neck area 4 of diameter smaller than that of the body 3 and connected to the latter by a shoulder 5.

La zone de goulot 4 est constituée par une partie cylindrique 6 raccordée à une zone annulaire de plus faible diamètre que la partie cylindrique 6, sur laquelle on a ménagé, par exemple par limage, une ligne 7 de précassage. Du côté opposé à la partie 6, la zone annulaire est rattachée à un bulbe 8, dont la pointe 9 a été fermée par soudure après remplissage du corps 3 de l'ampoule.The neck zone 4 is constituted by a cylindrical part 6 connected to an annular zone of smaller diameter than the cylindrical part 6, on which a pre-pressing line 7 has been provided, for example by filing. On the side opposite to the part 6, the annular zone is attached to a bulb 8, the tip 9 of which has been closed by welding after filling of the body 3 of the bulb.

Un manchon 10 en matière plastique thermorétractable entoure la partie cylindrique 6 du goulot, la zone annulaire sur laquelle est gravée la ligne 7 de précassage et une partie du bulbe 8. Ce manchon en matière plastique a été placé sur la zone de goulot 4 en posant sur l'épaulement 5 un tronçon de tube cylindrique formé d'une feuille de polyester thermorétractable ayant une épaisseur de 0,04 mm, et en le chauffant à 90 °C de façon à former un manchon 10, qui s'ajuste étroitement, sans coller, sur la zone de goulot 4.A sleeve 10 made of heat-shrinkable plastic surrounds the cylindrical part 6 of the neck, the annular zone on which the pre-crushing line 7 is engraved and part of the bulb 8. This plastic sleeve was placed on the neck zone 4 by placing on the shoulder 5 a section of cylindrical tube formed of a sheet of heat-shrinkable polyester having a thickness of 0.04 mm, and by heating it to 90 ° C so as to form a sleeve 10, which fits tightly, without stick on the neck area 4.

Le diamètre extérieur de la zone de goulot 4 au niveau de la ligne 7 de précassage est de 6 mm et la distance d (mesurée en projection sur l'axe X-X) entre la ligne 7 de précassage et la bordure du manchon 10 sur le bulbe 8 est d'environ 2 mm. L'épaisseur e du verre constitutif de l'ampoule est d'environ 0,7 mm. La viscosité du produit est de 45 centipoises et sa tension de surface est de 30 x 10⁻⁴ N/m (30 Dyn/cm).The outside diameter of the neck area 4 at the level of the pre-pressing line 7 is 6 mm and the distance d (measured in projection on the axis XX) between the pre-pressing line 7 and the edge of the sleeve 10 on the bulb. 8 is approximately 2 mm. The thickness e of the glass constituting the bulb is approximately 0.7 mm. The viscosity of the product is 45 centipoise and its surface tension is 30 x 10⁻⁴ N / m (30 Dyn / cm).

Lorsque l'utilisateur désire prélever le produit P contenu dans le corps 3 de l'ampoule, il appuie latéralement avec les doigts sur la zone de goulot 4 de part et d'autre de la ligne 7 de précassage jusqu'à obtenir la cassure du goulot selon la ligne 7 de précassage. L'utilisateur retire alors le bulbe 8, qui se détache du manchon 10. Comme visible sur la figure 2, une partie 10 a du manchon cylindrique reste fixée sur la partie cylindrique 6 de la zone de goulot 4 et une partie 10 b est libérée. Cette partie 10 b constitue un prolongement tronconique ayant un angle au sommet alpha de 45°, qui forme, en quelque sorte, un entonnoir inversé divergent à la sortie de l'ampoule.When the user wishes to take the product P contained in the body 3 of the bulb, he presses laterally with his fingers on the neck area 4 on either side of the pre-crushing line until the breakage of the neck along line 7 for pre-crushing. The user then removes the bulb 8, which detaches from the sleeve 10. As can be seen in FIG. 2, a part 10 a of the cylindrical sleeve remains fixed on the cylindrical part 6 of the neck area 4 and a part 10 b is released . This part 10b constitutes a frustoconical extension having an angle at the apex alpha of 45 °, which forms, in a way, a divergent inverted funnel at the outlet of the bulb.

L'utilisateur incline alors l'ampoule 1 pour que le produit P contenu dans le corps 3 s'écoule. En s'écoulant, le produit est d'abord en contact avec la paroi de verre de la partie cylindrique 6 de la zone de goulot 4, puis avec le plastique de la paroi interne du prolongement 10 b du manchon. Au passage, il franchit un décrochement 11 correspondant à l'épaisseur du verre au niveau de la ligne 7 de précassage. On constate que le produit P s'écoule facilement, sans qu'il soit nécessaire de secouer l' ampoule 1.The user then tilts the bulb 1 so that the product P contained in the body 3 flows. While flowing, the product is first in contact with the glass wall of the cylindrical part 6 of the neck zone 4, then with the plastic of the internal wall of the extension 10b of the sleeve. In passing, it crosses a step 11 corresponding to the thickness of the glass at the level of the pre-pressing line 7. It is found that the product P flows easily, without it being necessary to shake the bulb 1.

Claims (9)

  1. Break-open phial (1), the body (3) of which contains a fluid product (P), and which is equipped, close to one of its ends, with a neck region (4) which is symmetric about an axis (X-X), a break line (7) being formed on the said neck region (4), characterized in that the said neck region (4) is covered, at the break line (7), with a sleeve (10) made of plastic and extending, over at least one angular sector, beyond the break line (7) on the opposite side to the body (3), thereby forming, after the phial has been broken along the line (7), an extension (10b) whose projection onto the axis (X-X) has a length (d) at least equal to 20% of the diameter of the orifice defined by the edge of the part (6) of the neck which remains attached to the body (3), the plane tangential to the surface forming the said extension (10b) close to the line (7) forming with the axis (X-X) an angle alpha less than 60°.
  2. Phial according to Claim 1, characterized in that the angle alpha is between 40° and 50°.
  3. Phial according to one of Claims 1 or 2, characterized in that the sleeve (10) is made of heat shrinkable plastic.
  4. Phial according to one of Claims 1 to 3, characterized in that the sleeve (10) has a wall thickness of between 0.04 and 0.5 mm.
  5. Phial according to one of Claims 1 to 3, characterized in that the extension (10b) is formed right around the axis (X-X) over an angular sector of 360°.
  6. Phial according to Claim 5, characterized in that the free edge of the extension (10b) is substantially in a plane perpendicular to the axis (X-X).
  7. Phial according to one of Claims 1 to 6, characterized in that the extension (10b) consists of a collar of cylindrical, frustoconical or cylinder-conical shape.
  8. Phial according to one of Claims 1 to 7, characterized in that the neck region (4) consists of a substantially cylindrical part (6) and of a sealed bulb (8), the two being joined together by an annular region of smaller diameter on which the break line (7) is made.
  9. Phial according to one of Claims 1 to 8, characterized in that the sleeve (10) has, on the opposite side to the extension (10b), a length such that it covers most of that part of the neck region (4) which lies between the body (3) and the break line (7).
EP93902341A 1992-02-06 1992-12-17 Break-open phial Expired - Lifetime EP0590105B1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9201347A FR2687066A1 (en) 1992-02-06 1992-02-06 Auto-breakable ampoule
FR9201347 1992-02-06
PCT/FR1992/001196 WO1993015707A1 (en) 1992-02-06 1992-12-17 Break-open phial

Publications (2)

Publication Number Publication Date
EP0590105A1 EP0590105A1 (en) 1994-04-06
EP0590105B1 true EP0590105B1 (en) 1996-03-20

Family

ID=9426403

Family Applications (1)

Application Number Title Priority Date Filing Date
EP93902341A Expired - Lifetime EP0590105B1 (en) 1992-02-06 1992-12-17 Break-open phial

Country Status (7)

Country Link
US (1) US5379898A (en)
EP (1) EP0590105B1 (en)
JP (1) JP3433294B2 (en)
DE (1) DE69209292T2 (en)
ES (1) ES2085141T3 (en)
FR (1) FR2687066A1 (en)
WO (1) WO1993015707A1 (en)

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US7100600B2 (en) * 2001-03-20 2006-09-05 Aerogen, Inc. Fluid filled ampoules and methods for their use in aerosolizers
JP2004534763A (en) 2001-05-18 2004-11-18 カイロン コーポレイション Methods and unit dose formulations for inhaled administration of aminoglycoside antibiotics
EP1598059A1 (en) 2001-05-18 2005-11-23 Chiron Corporation Methods and unit dose formulations for the inhalation administration of aminoglycoside antibiotics
DE10209990B4 (en) * 2002-03-07 2007-02-08 Rudolf Gantenbrink Bottle and process for its production
ES2223235B1 (en) * 2002-08-19 2006-04-01 Ana Elvira Jimenez Florez SYSTEM OF OPENING, PROTECTION AND DOSAGE OF BLISTERS CONTAINING COSMETIC-PHARMACEUTICAL LIQUID PRODUCT.
US7490723B2 (en) * 2004-06-23 2009-02-17 Ricardo Levisman Easy-to-open glass ampoule and device
US20050111900A1 (en) * 2004-11-30 2005-05-26 Francesca Fazzolari Ampoule and method of use
US7581899B2 (en) * 2004-11-30 2009-09-01 James Alexander Corporation Dispenser and process
DE102005038619A1 (en) * 2005-08-16 2007-02-22 Pari GmbH Spezialisten für effektive Inhalation An inhalation therapy device with an ampoule for storing a medicament to be nebulised
DE202005014444U1 (en) * 2005-09-13 2005-11-17 Schreiner Group Gmbh & Co. Kg Container used as a pharmaceutical preparation has a predetermined breaking point which is completely surrounded by a film
US7976234B2 (en) 2006-04-28 2011-07-12 James Alexander Corporation Multi-chambered dispenser and process
DE102007056462B4 (en) * 2007-11-23 2011-10-27 Pari Pharma Gmbh Disposable ampoule for a device for generating aerosols
US8910830B2 (en) 2007-12-18 2014-12-16 James Alexander Corporation Container assembly
US8631941B2 (en) * 2010-04-22 2014-01-21 James Alexander Corporation Ampoule dispenser assembly and process
US20120267335A1 (en) * 2010-10-19 2012-10-25 Chris Cindrich Ampoule with protective sleeve for contamination prevention
US8827093B1 (en) * 2010-12-28 2014-09-09 Maria A. Mendez Bottle nipple device
JP6008254B2 (en) * 2011-04-06 2016-10-26 株式会社大塚製薬工場 Plastic ampules
CN104302554A (en) 2012-05-21 2015-01-21 赛诺菲 Unitary packaging for one container filled with a liquid pharmaceutical product
AU201715222S (en) * 2017-06-28 2017-10-03 Ami Cosmetic Co An ampoule cap
CN108785078A (en) * 2018-08-13 2018-11-13 吴德浩 A kind of transparent PP ampulla

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FR941772A (en) * 1947-02-17 1949-01-20 Pouring funnel
US4506793A (en) * 1983-08-01 1985-03-26 Cordis Corporation Breakable vial
US4826025A (en) * 1986-11-21 1989-05-02 Toppan Printing Co., Ltd. & Mect Corp. Ampoule package
DE3808308A1 (en) * 1988-03-12 1989-09-21 Merck Patent Gmbh OPENING AID FOR AMPOULES

Also Published As

Publication number Publication date
ES2085141T3 (en) 1996-05-16
FR2687066A1 (en) 1993-08-13
DE69209292D1 (en) 1996-04-25
FR2687066B1 (en) 1997-02-14
JP3433294B2 (en) 2003-08-04
EP0590105A1 (en) 1994-04-06
JPH06506626A (en) 1994-07-28
DE69209292T2 (en) 1996-11-21
US5379898A (en) 1995-01-10
WO1993015707A1 (en) 1993-08-19

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