EP0555247A1 - Progeniteurs de carbacycline epoxy, leur fabrication et utilisation - Google Patents

Progeniteurs de carbacycline epoxy, leur fabrication et utilisation

Info

Publication number
EP0555247A1
EP0555247A1 EP19910918068 EP91918068A EP0555247A1 EP 0555247 A1 EP0555247 A1 EP 0555247A1 EP 19910918068 EP19910918068 EP 19910918068 EP 91918068 A EP91918068 A EP 91918068A EP 0555247 A1 EP0555247 A1 EP 0555247A1
Authority
EP
European Patent Office
Prior art keywords
group
formula
tert
butyl
reaction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP19910918068
Other languages
German (de)
English (en)
Inventor
Michael Harre
Jürgen Westermann
Klaus Nickisch
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering AG filed Critical Schering AG
Publication of EP0555247A1 publication Critical patent/EP0555247A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic System
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • C07F7/1872—Preparation; Treatments not provided for in C07F7/20
    • C07F7/1892—Preparation; Treatments not provided for in C07F7/20 by reactions not provided for in C07F7/1876 - C07F7/1888
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic System
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)

Abstract

La présente invention se rapporte à des produits intermédiaires de carbacycline époxy, au procédé pour leur fabrication sur la base de Z-isomères des progéniteurs de carbacycline correspondants, ainsi qu'à leur utilisation pour la fabrication de carbacyclines pharmacologiquement efficaces.
EP19910918068 1990-10-26 1991-10-25 Progeniteurs de carbacycline epoxy, leur fabrication et utilisation Withdrawn EP0555247A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4034568A DE4034568A1 (de) 1990-10-26 1990-10-26 Epoxycarbacyclinvorstufen, deren herstellung und verwendung
DE4034568 1990-10-26

Publications (1)

Publication Number Publication Date
EP0555247A1 true EP0555247A1 (fr) 1993-08-18

Family

ID=6417343

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19910918068 Withdrawn EP0555247A1 (fr) 1990-10-26 1991-10-25 Progeniteurs de carbacycline epoxy, leur fabrication et utilisation

Country Status (12)

Country Link
EP (1) EP0555247A1 (fr)
JP (1) JPH06502149A (fr)
AU (1) AU659811B2 (fr)
CA (1) CA2092091A1 (fr)
DE (1) DE4034568A1 (fr)
HU (1) HUT65293A (fr)
IE (1) IE913764A1 (fr)
IL (1) IL99853A0 (fr)
NZ (1) NZ240384A (fr)
PT (1) PT99336A (fr)
WO (1) WO1992007857A1 (fr)
ZA (1) ZA918537B (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5857961A (en) * 1995-06-07 1999-01-12 Clarus Medical Systems, Inc. Surgical instrument for use with a viewing system

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5978179A (ja) * 1982-10-26 1984-05-04 Sankyo Co Ltd エポキシカルバサイクリン誘導体およびその製造法
DE3811577A1 (de) * 1988-03-31 1989-10-12 Schering Ag Neues verfahren zur herstellung von bicyclo(3.3.0)octan-3-on-derivaten

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See references of WO9207857A1 *

Also Published As

Publication number Publication date
WO1992007857A1 (fr) 1992-05-14
IE913764A1 (en) 1992-06-17
AU659811B2 (en) 1995-06-01
HU9301213D0 (en) 1993-08-30
IL99853A0 (en) 1992-08-18
DE4034568A1 (de) 1992-04-30
AU8744091A (en) 1992-05-26
JPH06502149A (ja) 1994-03-10
HUT65293A (en) 1994-05-02
CA2092091A1 (fr) 1992-04-27
ZA918537B (en) 1992-08-26
NZ240384A (en) 1993-12-23
PT99336A (pt) 1994-01-31

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 19930121

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE CH DE DK ES FR GB GR IT LI LU NL SE

RIN1 Information on inventor provided before grant (corrected)

Inventor name: NICKISCH, KLAUS

Inventor name: HARRE, MICHAEL

Inventor name: WESTERMANN, JUERGEN

17Q First examination report despatched

Effective date: 19950817

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 19951228