EP0464137A4 - Inhibition of hiv using synergistic combinations of nucleoside derivatives - Google Patents

Inhibition of hiv using synergistic combinations of nucleoside derivatives

Info

Publication number
EP0464137A4
EP0464137A4 EP19900905787 EP90905787A EP0464137A4 EP 0464137 A4 EP0464137 A4 EP 0464137A4 EP 19900905787 EP19900905787 EP 19900905787 EP 90905787 A EP90905787 A EP 90905787A EP 0464137 A4 EP0464137 A4 EP 0464137A4
Authority
EP
European Patent Office
Prior art keywords
hiv
inhibition
nucleoside derivatives
synergistic combinations
synergistic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP19900905787
Other languages
English (en)
Other versions
EP0464137A1 (en
Inventor
Vera Brankovan
Richard J. White
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Oncogen LP
Original Assignee
Oncogen LP
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oncogen LP filed Critical Oncogen LP
Publication of EP0464137A1 publication Critical patent/EP0464137A1/en
Publication of EP0464137A4 publication Critical patent/EP0464137A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP19900905787 1989-03-17 1990-03-16 Inhibition of hiv using synergistic combinations of nucleoside derivatives Withdrawn EP0464137A4 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US32493489A 1989-03-17 1989-03-17
US324934 1989-03-17
US40190889A 1989-09-01 1989-09-01
US401908 1989-09-01

Publications (2)

Publication Number Publication Date
EP0464137A1 EP0464137A1 (en) 1992-01-08
EP0464137A4 true EP0464137A4 (en) 1992-01-15

Family

ID=26984692

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19900905787 Withdrawn EP0464137A4 (en) 1989-03-17 1990-03-16 Inhibition of hiv using synergistic combinations of nucleoside derivatives

Country Status (19)

Country Link
EP (1) EP0464137A4 (xx)
JP (1) JPH04504850A (xx)
KR (1) KR920700653A (xx)
CN (1) CN1045791A (xx)
AU (1) AU5351490A (xx)
CA (1) CA2050473A1 (xx)
DD (1) DD301787A9 (xx)
FI (1) FI914367A0 (xx)
GR (1) GR1000618B (xx)
HU (1) HU208254B (xx)
IL (1) IL93783A0 (xx)
NO (1) NO913659L (xx)
NZ (1) NZ232912A (xx)
OA (1) OA09555A (xx)
PL (1) PL284343A1 (xx)
PT (1) PT93449A (xx)
WO (1) WO1990011081A1 (xx)
YU (1) YU53790A (xx)
ZW (1) ZW3290A1 (xx)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0513917T4 (da) * 1991-05-16 2001-06-25 Glaxo Group Ltd Antivirale kombinationer indeholdende nukleosidanaloger
CA2335617C (en) * 1998-06-24 2009-12-15 Emory University Use of 3'-azido-2',3'-dideoxyuridine in combination with further anti-hiv drugs for the manufacture of a medicament for the treatment of hiv
AU2002255707A1 (en) 2001-03-15 2002-10-03 Trustees Of Boston College, The Selective anti-viral nucleoside chain terminators

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1987001284A1 (en) * 1985-08-26 1987-03-12 United States Of America, Represented By The Unite Inhibition of in vitro infectivity and cytopathic effect of htlv-iii/lav by 2',3'-dideoxynosine, 2',3'-dideoxyguanosine, or 2',3'-dideoxyadenosine
GB8712115D0 (en) * 1987-05-22 1987-06-24 Hoffmann La Roche Pyrimidine derivatives
US4837311A (en) * 1987-06-22 1989-06-06 Hoffman-La Roche Inc. Anti-retroviral compounds
NZ226672A (en) * 1987-10-30 1991-07-26 Hoffmann La Roche 6-amino-9-(2,3-dideoxy-2-fluoro-b-d-threopentofuranosyl)-9h-purine derivatives and pharmaceutical compositions
US4908440A (en) * 1987-11-12 1990-03-13 Bristol Myers Company 2',3'-dideoxy-2'-fluoroarabinopyrimidine nucleosides

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
No further relevant documents have been disclosed. *

Also Published As

Publication number Publication date
OA09555A (en) 1993-01-31
HUT57988A (en) 1992-01-28
PL284343A1 (en) 1991-06-03
GR1000618B (el) 1992-08-31
NO913659D0 (no) 1991-09-17
EP0464137A1 (en) 1992-01-08
ZW3290A1 (en) 1990-11-07
JPH04504850A (ja) 1992-08-27
CN1045791A (zh) 1990-10-03
CA2050473A1 (en) 1990-09-18
GR900100189A (en) 1990-07-31
YU53790A (sh) 1993-05-28
NO913659L (no) 1991-10-18
FI914367A0 (fi) 1991-09-17
HU208254B (en) 1993-09-28
PT93449A (pt) 1990-11-07
DD301787A9 (de) 1994-01-13
NZ232912A (en) 1992-06-25
KR920700653A (ko) 1992-08-10
AU5351490A (en) 1990-10-22
IL93783A0 (en) 1990-12-23
WO1990011081A1 (en) 1990-10-04
HU902898D0 (en) 1991-12-30

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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17P Request for examination filed

Effective date: 19910918

AK Designated contracting states

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A4 Supplementary search report drawn up and despatched

Effective date: 19911125

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STAA Information on the status of an ep patent application or granted ep patent

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18D Application deemed to be withdrawn

Effective date: 19930921