NZ222527A - N 9 -cyclopentyl-substituted adenosine derivatives and intermediate compound and pharmaceutical compositions - Google Patents
N 9 -cyclopentyl-substituted adenosine derivatives and intermediate compound and pharmaceutical compositionsInfo
- Publication number
- NZ222527A NZ222527A NZ222527A NZ22252787A NZ222527A NZ 222527 A NZ222527 A NZ 222527A NZ 222527 A NZ222527 A NZ 222527A NZ 22252787 A NZ22252787 A NZ 22252787A NZ 222527 A NZ222527 A NZ 222527A
- Authority
- NZ
- New Zealand
- Prior art keywords
- cyclopentyl
- pharmaceutical compositions
- intermediate compound
- adenosine derivatives
- substituted adenosine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/38—Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D303/46—Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals by amide or nitrile radicals
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Neurosurgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Vascular Medicine (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Psychiatry (AREA)
- Urology & Nephrology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US93132786A | 1986-11-14 | 1986-11-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ222527A true NZ222527A (en) | 1990-08-28 |
Family
ID=25460605
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ222527A NZ222527A (en) | 1986-11-14 | 1987-11-12 | N 9 -cyclopentyl-substituted adenosine derivatives and intermediate compound and pharmaceutical compositions |
Country Status (15)
| Country | Link |
|---|---|
| EP (1) | EP0267878A1 (en) |
| JP (1) | JPS63135384A (en) |
| KR (1) | KR880006241A (en) |
| AU (1) | AU608258B2 (en) |
| CA (1) | CA1288431C (en) |
| DD (1) | DD273833A5 (en) |
| DK (1) | DK596087A (en) |
| FI (1) | FI874982A (en) |
| HU (1) | HU198489B (en) |
| IL (1) | IL84414A0 (en) |
| NO (1) | NO166184C (en) |
| NZ (1) | NZ222527A (en) |
| PH (1) | PH25044A (en) |
| PT (1) | PT86120B (en) |
| ZA (1) | ZA878527B (en) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IN164556B (en) * | 1986-03-06 | 1989-04-08 | Takeda Chemical Industries Ltd | |
| US5063233A (en) * | 1986-11-14 | 1991-11-05 | Ciba-Geigy Corporation | N9 -cyclopentyl-substituted adenine derivatives useful as adenosine receptor agonists |
| US5015739A (en) * | 1988-04-22 | 1991-05-14 | Schering Corporation | Processes for preparation of cyclopentyl purine derivatives |
| GB8813148D0 (en) * | 1988-06-03 | 1988-07-06 | Glaxo Group Ltd | Chemical compounds |
| US5216141A (en) * | 1988-06-06 | 1993-06-01 | Benner Steven A | Oligonucleotide analogs containing sulfur linkages |
| HU204843B (en) * | 1988-09-27 | 1992-02-28 | Merrell Dow Pharma | Process for producing 2'-halogen-methylidene adenosine derivatives and pharmaceutical compositions comprising same |
| GB8826205D0 (en) * | 1988-11-09 | 1988-12-14 | Wellcome Found | Heterocyclic compounds |
| US5312961A (en) * | 1989-02-14 | 1994-05-17 | Elf Sanofi | 2-amino-7-hydroxytetralin carboxylalkyl ethers |
| GB8916479D0 (en) * | 1989-07-19 | 1989-09-06 | Glaxo Group Ltd | Chemical process |
| GB8916478D0 (en) * | 1989-07-19 | 1989-09-06 | Glaxo Group Ltd | Chemical process |
| GB8926417D0 (en) * | 1989-11-22 | 1990-01-10 | Wellcome Found | Heterocyclic compounds |
| US5514688A (en) * | 1990-09-14 | 1996-05-07 | Merrell Dow Pharmaceuticals Inc. | Carbocyclic adenosine analogs useful as immunosuppressants |
| US5470857A (en) * | 1990-09-14 | 1995-11-28 | Marion Merrell Dow Inc. | Carbocyclic nucleoside analogs useful as immunosuppressants |
| US5561134A (en) * | 1990-09-25 | 1996-10-01 | Rhone-Poulenc Rorer Pharmaceuticals Inc. | Compounds having antihypertensive, cardioprotective, anti-ischemic and antilipolytic properties |
| GB9108376D0 (en) * | 1991-04-19 | 1991-06-05 | Enzymatix Ltd | Cyclopentenes |
| US5206222A (en) * | 1991-05-22 | 1993-04-27 | Vanderbilt University | Methods for the reduction of myocardial reperfusion injury |
| US5723466A (en) * | 1991-12-06 | 1998-03-03 | Hoechst Marion Roussel, Inc. | Trans cyclopentanyl purine analogs useful as immunosuppressants |
| US5817660A (en) * | 1991-12-06 | 1998-10-06 | Hoechst Marion Roussel, Inc. | Trans cyclopentanyl purine analogs useful as immunosuppressants |
| US5817661A (en) * | 1991-12-06 | 1998-10-06 | Hoechst Marion Roussel, Inc. | Trans cyclopentanyl purine analogs useful as immunosuppressants |
| US5817672A (en) * | 1991-12-06 | 1998-10-06 | Hoechst Marion Roussel, Inc. | Trans cyclopentanyl purine analogs useful as immunosuppressants |
| FR2685918B1 (en) * | 1992-01-08 | 1995-06-23 | Union Pharma Scient Appl | NOVEL ADENOSINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. |
| AU3961493A (en) * | 1992-04-21 | 1993-11-18 | Chiroscience Limited | Chiral cyclopentene derivatives and their preparation |
| US5840923A (en) * | 1992-04-21 | 1998-11-24 | Chiroscience Limited | Chiral cyclopentene derivatives and their preparation |
| IT1254915B (en) * | 1992-04-24 | 1995-10-11 | Gloria Cristalli | ADENOSINE DERIVATIVES FOR ACTIVITY A2 AGONIST |
| EP0577558A2 (en) * | 1992-07-01 | 1994-01-05 | Ciba-Geigy Ag | Carbocyclic nucleosides having bicyclic rings, oligonucleotides therefrom, process for their preparation, their use and intermediates |
| GB9414208D0 (en) * | 1994-07-14 | 1994-08-31 | Glaxo Group Ltd | Compounds |
| WO1996019478A1 (en) * | 1994-12-19 | 1996-06-27 | Novartis Ag | 6'-substituted carbocyclic nucleosides |
| AU4343500A (en) | 1999-04-16 | 2000-11-02 | Schering Corporation | Use of azetidinone compounds |
| US6949640B2 (en) * | 2000-02-18 | 2005-09-27 | Southern Research Institute | Method for synthesizing 2-chloro-9-(2-fluoro-β-D-arabinofuranosyl)-9H-purin-6-amine |
| US20050033044A1 (en) | 2003-05-19 | 2005-02-10 | Bristol-Myers Squibb Pharma Company | Methods for preparing 2-alkynyladenosine derivatives |
| GT200500281A (en) | 2004-10-22 | 2006-04-24 | Novartis Ag | ORGANIC COMPOUNDS. |
| GB0500785D0 (en) * | 2005-01-14 | 2005-02-23 | Novartis Ag | Organic compounds |
| SI2013211T1 (en) | 2006-04-21 | 2012-07-31 | Novartis Ag | Purine derivatives for use as adenosin a2a receptor agonists |
| GB0607950D0 (en) | 2006-04-21 | 2006-05-31 | Novartis Ag | Organic compounds |
| EP1889846A1 (en) | 2006-07-13 | 2008-02-20 | Novartis AG | Purine derivatives as A2a agonists |
| EP1903044A1 (en) | 2006-09-14 | 2008-03-26 | Novartis AG | Adenosine Derivatives as A2A Receptor Agonists |
| CN103476415B (en) | 2010-11-16 | 2017-09-22 | 南加州大学 | For the CBP/ catenin antagonists for the Asymmetric division for strengthening adult stem cell |
| CN105061431B (en) * | 2015-07-28 | 2017-03-29 | 山东百诺医药股份有限公司 | 6‑N‑（2‑（Methyl mercapto）Ethyl）‑2‑（（3,3,3 trifluoro propyls）It is thio）9H purine and its preparation method and application |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2610985A1 (en) * | 1976-03-16 | 1977-09-29 | Byk Gulden Lomberg Chem Fab | (1)-Aminopurinyl-(1)-deoxyribofuranuronic acid medicaments - with circulatory, cardiac and metabolic activity |
| US4345984A (en) * | 1981-03-02 | 1982-08-24 | The Procter & Gamble Company | Novel prostaglandin analogues and process for making same |
| US4543255A (en) * | 1984-05-10 | 1985-09-24 | Southern Research Institute | Carbocyclic analogs of purine 2'-deoxyribofuranosides |
| US4742064A (en) * | 1985-09-10 | 1988-05-03 | Regents Of The University Of Minnesota | Antiviral carbocyclic analogs of xylofuranosylpurines |
-
1987
- 1987-11-09 IL IL84414A patent/IL84414A0/en unknown
- 1987-11-09 EP EP87810647A patent/EP0267878A1/en not_active Withdrawn
- 1987-11-11 FI FI874982A patent/FI874982A/en not_active IP Right Cessation
- 1987-11-12 PT PT86120A patent/PT86120B/en not_active IP Right Cessation
- 1987-11-12 CA CA000551656A patent/CA1288431C/en not_active Expired - Lifetime
- 1987-11-12 NZ NZ222527A patent/NZ222527A/en unknown
- 1987-11-12 DD DD87308972A patent/DD273833A5/en not_active IP Right Cessation
- 1987-11-13 DK DK596087A patent/DK596087A/en not_active Application Discontinuation
- 1987-11-13 NO NO874749A patent/NO166184C/en unknown
- 1987-11-13 PH PH36065A patent/PH25044A/en unknown
- 1987-11-13 ZA ZA878527A patent/ZA878527B/en unknown
- 1987-11-13 HU HU875070A patent/HU198489B/en unknown
- 1987-11-13 JP JP62285628A patent/JPS63135384A/en active Pending
- 1987-11-13 AU AU81193/87A patent/AU608258B2/en not_active Ceased
- 1987-11-23 KR KR870012780A patent/KR880006241A/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| NO166184B (en) | 1991-03-04 |
| AU608258B2 (en) | 1991-03-28 |
| ZA878527B (en) | 1988-05-16 |
| DK596087D0 (en) | 1987-11-13 |
| KR880006241A (en) | 1988-07-22 |
| DK596087A (en) | 1988-05-15 |
| NO166184C (en) | 1991-06-12 |
| FI874982A0 (en) | 1987-11-11 |
| DD273833A5 (en) | 1989-11-29 |
| CA1288431C (en) | 1991-09-03 |
| JPS63135384A (en) | 1988-06-07 |
| NO874749D0 (en) | 1987-11-13 |
| PT86120A (en) | 1987-12-01 |
| NO874749L (en) | 1988-05-16 |
| PH25044A (en) | 1991-01-28 |
| AU8119387A (en) | 1988-05-19 |
| IL84414A0 (en) | 1988-04-29 |
| EP0267878A1 (en) | 1988-05-18 |
| HU198489B (en) | 1989-10-30 |
| PT86120B (en) | 1990-08-31 |
| HUT45057A (en) | 1988-05-30 |
| FI874982A (en) | 1988-05-15 |
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