AU8119387A - N9-cyclopentyl-substituted adenine derivatives - Google Patents
N9-cyclopentyl-substituted adenine derivativesInfo
- Publication number
- AU8119387A AU8119387A AU81193/87A AU8119387A AU8119387A AU 8119387 A AU8119387 A AU 8119387A AU 81193/87 A AU81193/87 A AU 81193/87A AU 8119387 A AU8119387 A AU 8119387A AU 8119387 A AU8119387 A AU 8119387A
- Authority
- AU
- Australia
- Prior art keywords
- cyclopentyl
- adenine derivatives
- substituted adenine
- substituted
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/38—Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D303/46—Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals by amide or nitrile radicals
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Neurosurgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Vascular Medicine (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Psychiatry (AREA)
- Urology & Nephrology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US93132786A | 1986-11-14 | 1986-11-14 | |
US931327 | 1986-11-14 |
Publications (2)
Publication Number | Publication Date |
---|---|
AU8119387A true AU8119387A (en) | 1988-05-19 |
AU608258B2 AU608258B2 (en) | 1991-03-28 |
Family
ID=25460605
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU81193/87A Ceased AU608258B2 (en) | 1986-11-14 | 1987-11-13 | N9-cyclopentyl-substituted adenine derivatives |
Country Status (15)
Country | Link |
---|---|
EP (1) | EP0267878A1 (en) |
JP (1) | JPS63135384A (en) |
KR (1) | KR880006241A (en) |
AU (1) | AU608258B2 (en) |
CA (1) | CA1288431C (en) |
DD (1) | DD273833A5 (en) |
DK (1) | DK596087A (en) |
FI (1) | FI874982A (en) |
HU (1) | HU198489B (en) |
IL (1) | IL84414A0 (en) |
NO (1) | NO166184C (en) |
NZ (1) | NZ222527A (en) |
PH (1) | PH25044A (en) |
PT (1) | PT86120B (en) |
ZA (1) | ZA878527B (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU596400B2 (en) * | 1986-03-06 | 1990-05-03 | Takeda Chemical Industries Ltd. | Carbocyclic purine nucleosides, their production and use |
AU621664B2 (en) * | 1988-09-27 | 1992-03-19 | Merrell Dow Pharmaceuticals Inc. | Novel 2'-halomethylidene, 2'-ethenylidene and 2'-ethynyl adenosine derivatives |
AU635209B2 (en) * | 1988-06-06 | 1993-03-18 | Steven Albert Benner | Oligonucleotide analogs containing sulfur |
Families Citing this family (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5063233A (en) * | 1986-11-14 | 1991-11-05 | Ciba-Geigy Corporation | N9 -cyclopentyl-substituted adenine derivatives useful as adenosine receptor agonists |
US5015739A (en) * | 1988-04-22 | 1991-05-14 | Schering Corporation | Processes for preparation of cyclopentyl purine derivatives |
GB8813148D0 (en) * | 1988-06-03 | 1988-07-06 | Glaxo Group Ltd | Chemical compounds |
GB8826205D0 (en) * | 1988-11-09 | 1988-12-14 | Wellcome Found | Heterocyclic compounds |
US5312961A (en) * | 1989-02-14 | 1994-05-17 | Elf Sanofi | 2-amino-7-hydroxytetralin carboxylalkyl ethers |
GB8916479D0 (en) * | 1989-07-19 | 1989-09-06 | Glaxo Group Ltd | Chemical process |
GB8916478D0 (en) * | 1989-07-19 | 1989-09-06 | Glaxo Group Ltd | Chemical process |
GB8926417D0 (en) * | 1989-11-22 | 1990-01-10 | Wellcome Found | Heterocyclic compounds |
US5514688A (en) * | 1990-09-14 | 1996-05-07 | Merrell Dow Pharmaceuticals Inc. | Carbocyclic adenosine analogs useful as immunosuppressants |
US5470857A (en) * | 1990-09-14 | 1995-11-28 | Marion Merrell Dow Inc. | Carbocyclic nucleoside analogs useful as immunosuppressants |
US5561134A (en) * | 1990-09-25 | 1996-10-01 | Rhone-Poulenc Rorer Pharmaceuticals Inc. | Compounds having antihypertensive, cardioprotective, anti-ischemic and antilipolytic properties |
GB9108376D0 (en) * | 1991-04-19 | 1991-06-05 | Enzymatix Ltd | Cyclopentenes |
US5206222A (en) * | 1991-05-22 | 1993-04-27 | Vanderbilt University | Methods for the reduction of myocardial reperfusion injury |
US5723466A (en) * | 1991-12-06 | 1998-03-03 | Hoechst Marion Roussel, Inc. | Trans cyclopentanyl purine analogs useful as immunosuppressants |
US5817660A (en) * | 1991-12-06 | 1998-10-06 | Hoechst Marion Roussel, Inc. | Trans cyclopentanyl purine analogs useful as immunosuppressants |
US5817661A (en) * | 1991-12-06 | 1998-10-06 | Hoechst Marion Roussel, Inc. | Trans cyclopentanyl purine analogs useful as immunosuppressants |
US5817672A (en) * | 1991-12-06 | 1998-10-06 | Hoechst Marion Roussel, Inc. | Trans cyclopentanyl purine analogs useful as immunosuppressants |
FR2685918B1 (en) * | 1992-01-08 | 1995-06-23 | Union Pharma Scient Appl | NOVEL ADENOSINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. |
AU3961493A (en) * | 1992-04-21 | 1993-11-18 | Chiroscience Limited | Chiral cyclopentene derivatives and their preparation |
US5840923A (en) * | 1992-04-21 | 1998-11-24 | Chiroscience Limited | Chiral cyclopentene derivatives and their preparation |
IT1254915B (en) * | 1992-04-24 | 1995-10-11 | Gloria Cristalli | ADENOSINE DERIVATIVES FOR ACTIVITY A2 AGONIST |
EP0577558A2 (en) * | 1992-07-01 | 1994-01-05 | Ciba-Geigy Ag | Carbocyclic nucleosides having bicyclic rings, oligonucleotides therefrom, process for their preparation, their use and intermediates |
GB9414208D0 (en) * | 1994-07-14 | 1994-08-31 | Glaxo Group Ltd | Compounds |
WO1996019478A1 (en) * | 1994-12-19 | 1996-06-27 | Novartis Ag | 6'-substituted carbocyclic nucleosides |
AU4343500A (en) | 1999-04-16 | 2000-11-02 | Schering Corporation | Use of azetidinone compounds |
US6949640B2 (en) * | 2000-02-18 | 2005-09-27 | Southern Research Institute | Method for synthesizing 2-chloro-9-(2-fluoro-β-D-arabinofuranosyl)-9H-purin-6-amine |
US20050033044A1 (en) | 2003-05-19 | 2005-02-10 | Bristol-Myers Squibb Pharma Company | Methods for preparing 2-alkynyladenosine derivatives |
GT200500281A (en) | 2004-10-22 | 2006-04-24 | Novartis Ag | ORGANIC COMPOUNDS. |
GB0500785D0 (en) * | 2005-01-14 | 2005-02-23 | Novartis Ag | Organic compounds |
SI2013211T1 (en) | 2006-04-21 | 2012-07-31 | Novartis Ag | Purine derivatives for use as adenosin a2a receptor agonists |
GB0607950D0 (en) | 2006-04-21 | 2006-05-31 | Novartis Ag | Organic compounds |
EP1889846A1 (en) | 2006-07-13 | 2008-02-20 | Novartis AG | Purine derivatives as A2a agonists |
EP1903044A1 (en) | 2006-09-14 | 2008-03-26 | Novartis AG | Adenosine Derivatives as A2A Receptor Agonists |
CN103476415B (en) | 2010-11-16 | 2017-09-22 | 南加州大学 | For the CBP/ catenin antagonists for the Asymmetric division for strengthening adult stem cell |
CN105061431B (en) * | 2015-07-28 | 2017-03-29 | 山东百诺医药股份有限公司 | 6‑N‑(2‑(Methyl mercapto)Ethyl)‑2‑((3,3,3 trifluoro propyls)It is thio)9H purine and its preparation method and application |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2610985A1 (en) * | 1976-03-16 | 1977-09-29 | Byk Gulden Lomberg Chem Fab | (1)-Aminopurinyl-(1)-deoxyribofuranuronic acid medicaments - with circulatory, cardiac and metabolic activity |
US4345984A (en) * | 1981-03-02 | 1982-08-24 | The Procter & Gamble Company | Novel prostaglandin analogues and process for making same |
US4543255A (en) * | 1984-05-10 | 1985-09-24 | Southern Research Institute | Carbocyclic analogs of purine 2'-deoxyribofuranosides |
US4742064A (en) * | 1985-09-10 | 1988-05-03 | Regents Of The University Of Minnesota | Antiviral carbocyclic analogs of xylofuranosylpurines |
-
1987
- 1987-11-09 IL IL84414A patent/IL84414A0/en unknown
- 1987-11-09 EP EP87810647A patent/EP0267878A1/en not_active Withdrawn
- 1987-11-11 FI FI874982A patent/FI874982A/en not_active IP Right Cessation
- 1987-11-12 PT PT86120A patent/PT86120B/en not_active IP Right Cessation
- 1987-11-12 CA CA000551656A patent/CA1288431C/en not_active Expired - Lifetime
- 1987-11-12 NZ NZ222527A patent/NZ222527A/en unknown
- 1987-11-12 DD DD87308972A patent/DD273833A5/en not_active IP Right Cessation
- 1987-11-13 DK DK596087A patent/DK596087A/en not_active Application Discontinuation
- 1987-11-13 NO NO874749A patent/NO166184C/en unknown
- 1987-11-13 PH PH36065A patent/PH25044A/en unknown
- 1987-11-13 ZA ZA878527A patent/ZA878527B/en unknown
- 1987-11-13 HU HU875070A patent/HU198489B/en unknown
- 1987-11-13 JP JP62285628A patent/JPS63135384A/en active Pending
- 1987-11-13 AU AU81193/87A patent/AU608258B2/en not_active Ceased
- 1987-11-23 KR KR870012780A patent/KR880006241A/en not_active Application Discontinuation
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU596400B2 (en) * | 1986-03-06 | 1990-05-03 | Takeda Chemical Industries Ltd. | Carbocyclic purine nucleosides, their production and use |
AU635209B2 (en) * | 1988-06-06 | 1993-03-18 | Steven Albert Benner | Oligonucleotide analogs containing sulfur |
AU621664B2 (en) * | 1988-09-27 | 1992-03-19 | Merrell Dow Pharmaceuticals Inc. | Novel 2'-halomethylidene, 2'-ethenylidene and 2'-ethynyl adenosine derivatives |
Also Published As
Publication number | Publication date |
---|---|
NO166184B (en) | 1991-03-04 |
AU608258B2 (en) | 1991-03-28 |
ZA878527B (en) | 1988-05-16 |
DK596087D0 (en) | 1987-11-13 |
KR880006241A (en) | 1988-07-22 |
DK596087A (en) | 1988-05-15 |
NO166184C (en) | 1991-06-12 |
FI874982A0 (en) | 1987-11-11 |
DD273833A5 (en) | 1989-11-29 |
CA1288431C (en) | 1991-09-03 |
JPS63135384A (en) | 1988-06-07 |
NO874749D0 (en) | 1987-11-13 |
PT86120A (en) | 1987-12-01 |
NO874749L (en) | 1988-05-16 |
PH25044A (en) | 1991-01-28 |
IL84414A0 (en) | 1988-04-29 |
EP0267878A1 (en) | 1988-05-18 |
NZ222527A (en) | 1990-08-28 |
HU198489B (en) | 1989-10-30 |
PT86120B (en) | 1990-08-31 |
HUT45057A (en) | 1988-05-30 |
FI874982A (en) | 1988-05-15 |
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