CN1045791A - 使用核苷衍生物的协同组合物抑制人免疫缺陷病毒 - Google Patents

使用核苷衍生物的协同组合物抑制人免疫缺陷病毒 Download PDF

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Publication number
CN1045791A
CN1045791A CN90102298A CN90102298A CN1045791A CN 1045791 A CN1045791 A CN 1045791A CN 90102298 A CN90102298 A CN 90102298A CN 90102298 A CN90102298 A CN 90102298A CN 1045791 A CN1045791 A CN 1045791A
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CN
China
Prior art keywords
hiv
dideoxy
nucleoside derivates
ddi
cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN90102298A
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English (en)
Chinese (zh)
Inventor
维拉·布兰可芬
理查德·J·怀特
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Oncogen LP
Original Assignee
Oncogen LP
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oncogen LP filed Critical Oncogen LP
Publication of CN1045791A publication Critical patent/CN1045791A/zh
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN90102298A 1989-03-17 1990-03-17 使用核苷衍生物的协同组合物抑制人免疫缺陷病毒 Pending CN1045791A (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US32493489A 1989-03-17 1989-03-17
US324,934 1989-03-17
US40190889A 1989-09-01 1989-09-01
US401,908 1989-09-01

Publications (1)

Publication Number Publication Date
CN1045791A true CN1045791A (zh) 1990-10-03

Family

ID=26984692

Family Applications (1)

Application Number Title Priority Date Filing Date
CN90102298A Pending CN1045791A (zh) 1989-03-17 1990-03-17 使用核苷衍生物的协同组合物抑制人免疫缺陷病毒

Country Status (19)

Country Link
EP (1) EP0464137A4 (xx)
JP (1) JPH04504850A (xx)
KR (1) KR920700653A (xx)
CN (1) CN1045791A (xx)
AU (1) AU5351490A (xx)
CA (1) CA2050473A1 (xx)
DD (1) DD301787A9 (xx)
FI (1) FI914367A0 (xx)
GR (1) GR1000618B (xx)
HU (1) HU208254B (xx)
IL (1) IL93783A0 (xx)
NO (1) NO913659L (xx)
NZ (1) NZ232912A (xx)
OA (1) OA09555A (xx)
PL (1) PL284343A1 (xx)
PT (1) PT93449A (xx)
WO (1) WO1990011081A1 (xx)
YU (1) YU53790A (xx)
ZW (1) ZW3290A1 (xx)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0513917T4 (da) * 1991-05-16 2001-06-25 Glaxo Group Ltd Antivirale kombinationer indeholdende nukleosidanaloger
CA2335617C (en) * 1998-06-24 2009-12-15 Emory University Use of 3'-azido-2',3'-dideoxyuridine in combination with further anti-hiv drugs for the manufacture of a medicament for the treatment of hiv
AU2002255707A1 (en) 2001-03-15 2002-10-03 Trustees Of Boston College, The Selective anti-viral nucleoside chain terminators

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1987001284A1 (en) * 1985-08-26 1987-03-12 United States Of America, Represented By The Unite Inhibition of in vitro infectivity and cytopathic effect of htlv-iii/lav by 2',3'-dideoxynosine, 2',3'-dideoxyguanosine, or 2',3'-dideoxyadenosine
GB8712115D0 (en) * 1987-05-22 1987-06-24 Hoffmann La Roche Pyrimidine derivatives
US4837311A (en) * 1987-06-22 1989-06-06 Hoffman-La Roche Inc. Anti-retroviral compounds
NZ226672A (en) * 1987-10-30 1991-07-26 Hoffmann La Roche 6-amino-9-(2,3-dideoxy-2-fluoro-b-d-threopentofuranosyl)-9h-purine derivatives and pharmaceutical compositions
US4908440A (en) * 1987-11-12 1990-03-13 Bristol Myers Company 2',3'-dideoxy-2'-fluoroarabinopyrimidine nucleosides

Also Published As

Publication number Publication date
OA09555A (en) 1993-01-31
HUT57988A (en) 1992-01-28
PL284343A1 (en) 1991-06-03
GR1000618B (el) 1992-08-31
NO913659D0 (no) 1991-09-17
EP0464137A1 (en) 1992-01-08
ZW3290A1 (en) 1990-11-07
JPH04504850A (ja) 1992-08-27
CA2050473A1 (en) 1990-09-18
GR900100189A (en) 1990-07-31
YU53790A (sh) 1993-05-28
NO913659L (no) 1991-10-18
FI914367A0 (fi) 1991-09-17
HU208254B (en) 1993-09-28
PT93449A (pt) 1990-11-07
DD301787A9 (de) 1994-01-13
NZ232912A (en) 1992-06-25
KR920700653A (ko) 1992-08-10
AU5351490A (en) 1990-10-22
EP0464137A4 (en) 1992-01-15
IL93783A0 (en) 1990-12-23
WO1990011081A1 (en) 1990-10-04
HU902898D0 (en) 1991-12-30

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C06 Publication
PB01 Publication
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SE01 Entry into force of request for substantive examination
C01 Deemed withdrawal of patent application (patent law 1993)
WD01 Invention patent application deemed withdrawn after publication