EP0356964A3 - Méthode pour la détermination d'une substance de liaison spécifique - Google Patents
Méthode pour la détermination d'une substance de liaison spécifique Download PDFInfo
- Publication number
- EP0356964A3 EP0356964A3 EP19890115852 EP89115852A EP0356964A3 EP 0356964 A3 EP0356964 A3 EP 0356964A3 EP 19890115852 EP19890115852 EP 19890115852 EP 89115852 A EP89115852 A EP 89115852A EP 0356964 A3 EP0356964 A3 EP 0356964A3
- Authority
- EP
- European Patent Office
- Prior art keywords
- specific binding
- substance
- determination
- binding substance
- receptor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000126 substance Substances 0.000 title abstract 4
- 230000009870 specific binding Effects 0.000 title abstract 2
- 230000027455 binding Effects 0.000 abstract 2
- 230000004520 agglutination Effects 0.000 abstract 1
- 238000011534 incubation Methods 0.000 abstract 1
- 238000005259 measurement Methods 0.000 abstract 1
- 239000012488 sample solution Substances 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54306—Solid-phase reaction mechanisms
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6854—Immunoglobulins
- G01N33/6857—Antibody fragments
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Medicinal Chemistry (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE3829245 | 1988-08-29 | ||
DE3829245A DE3829245A1 (de) | 1988-08-29 | 1988-08-29 | Verfahren zur bestimmung einer spezifisch bindefaehigen substanz |
Publications (3)
Publication Number | Publication Date |
---|---|
EP0356964A2 EP0356964A2 (fr) | 1990-03-07 |
EP0356964A3 true EP0356964A3 (fr) | 1991-01-16 |
EP0356964B1 EP0356964B1 (fr) | 1995-01-18 |
Family
ID=6361800
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP89115852A Expired - Lifetime EP0356964B1 (fr) | 1988-08-29 | 1989-08-28 | Méthode pour la détermination d'une substance de liaison spécifique |
Country Status (9)
Country | Link |
---|---|
US (1) | US5362655A (fr) |
EP (1) | EP0356964B1 (fr) |
JP (1) | JPH0765998B2 (fr) |
KR (1) | KR920000056B1 (fr) |
AT (1) | ATE117433T1 (fr) |
AU (1) | AU607348B2 (fr) |
DE (2) | DE3829245A1 (fr) |
ES (1) | ES2068222T3 (fr) |
ZA (1) | ZA896535B (fr) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3915135A1 (de) * | 1989-05-09 | 1990-11-15 | Boehringer Mannheim Gmbh | Verfahren zum nachweis spezifisch bindefaehiger substanzen in koerperfluessigkeiten |
DE4009848A1 (de) * | 1990-03-27 | 1991-10-02 | Boehringer Mannheim Gmbh | Verfahren zum nachweis von phosphoryliertes tyrosin enthaltenden proteinen |
DE4020204A1 (de) * | 1990-06-25 | 1992-01-02 | Boehringer Mannheim Gmbh | Durchfuehrung eines homogenen immunoassays nach dem agglutinationsprinzip |
US6274325B1 (en) | 1990-06-25 | 2001-08-14 | Boehringer Mannheim Gmbh | Method for carrying out a homogeneous-immunoassay based on agglutination |
EP0510483A1 (fr) * | 1991-04-22 | 1992-10-28 | Boehringer Ingelheim Pharmaceuticals Inc. | Procédé pour la détection des virus |
DE4134833A1 (de) * | 1991-09-25 | 1993-04-01 | Boehringer Mannheim Gmbh | Verfahren zur bestimmung von fibrin |
WO1996022533A1 (fr) * | 1995-01-18 | 1996-07-25 | First Medical, Inc. | Procede pour immobiliser des haptenes sur un article de test |
DE19649390A1 (de) * | 1996-11-29 | 1998-06-04 | Boehringer Mannheim Gmbh | Antigenspezifischer IgG-Nachweis |
US20030003602A1 (en) * | 2001-03-07 | 2003-01-02 | Bernd Vogt | Homogeneous immunoassay method |
EP1239285A1 (fr) * | 2001-03-07 | 2002-09-11 | Roche Diagnostics GmbH | Méthode améliorée pour un procédé d'essai immunologique homogène |
US7939283B2 (en) * | 2001-11-01 | 2011-05-10 | Fisher Scientific Company L.L.C. | Analyte binding turbidity assay |
US20030109067A1 (en) * | 2001-12-06 | 2003-06-12 | Immunetech, Inc. | Homogeneous immunoassays for multiple allergens |
EP1321768A1 (fr) * | 2001-12-18 | 2003-06-25 | Roche Diagnostics GmbH | Diagnostic de l'endométriose à partir du flux menstruel |
US20050118727A1 (en) * | 2003-12-01 | 2005-06-02 | Carsten Schelp | Conjugates and their use in detection methods |
CA2547351A1 (fr) * | 2003-12-01 | 2005-07-07 | Dade Behring Marburg Gmbh | Procede de detection homogene |
WO2009072385A1 (fr) * | 2007-12-07 | 2009-06-11 | Alfresa Pharma Corporation | Procédé d'immunodosage d'échantillon à l'aide d'une réaction d'agrégation de microparticules et coffret de dosage |
JP2010053118A (ja) * | 2008-07-28 | 2010-03-11 | Fujifilm Corp | ビオチン化チロキシン |
KR101515020B1 (ko) * | 2013-11-13 | 2015-04-24 | 에스케이텔레콤 주식회사 | 햅텐 및 이에 결합하는 항체를 레퍼런스 항체로 이용하는 면역학적 측정 방법 및 상기 레퍼런스 항체를 이용한 면역학적 측정장치 |
CN107576806A (zh) * | 2017-09-30 | 2018-01-12 | 安徽伊普诺康生物技术股份有限公司 | 一种粒细胞集落刺激因子检测试剂盒及其使用方法 |
CN107748251A (zh) * | 2017-09-30 | 2018-03-02 | 安徽伊普诺康生物技术股份有限公司 | 一种粒细胞集落刺激因子检测试剂盒的制备方法 |
KR102161665B1 (ko) | 2019-10-25 | 2020-10-05 | 김일도 | 폐카본필터 재생 시스템 및 그 방법 |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2013211A (en) * | 1978-01-26 | 1979-08-08 | Technicon Instr | Immunoassays using f(ab')2 fragments |
EP0138297A1 (fr) * | 1983-09-30 | 1985-04-24 | Becton Dickinson and Company | Suspensions de particules pour l'immuno - agglutination |
EP0147848A2 (fr) * | 1984-01-02 | 1985-07-10 | Roche Diagnostics GmbH | Méthode pour la détermination d'un antigèn polyvalent et réactif |
WO1988005913A1 (fr) * | 1987-01-29 | 1988-08-11 | Cytosignet, Inc. | Detection d'un analyte dans des echantillons contenant des particules |
US4829011A (en) * | 1987-08-27 | 1989-05-09 | Biotrack, Inc. | Agglutination assay |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1451669A (en) * | 1974-01-02 | 1976-10-06 | Radiochemical Centre Ltd | Protein staining |
US4184849A (en) * | 1977-12-05 | 1980-01-22 | Technicon Instruments Corporation | Mixed agglutination |
JPS5510590A (en) * | 1978-05-04 | 1980-01-25 | Wellcome Found | Enzyme immunity quantity analysis |
US4289747A (en) * | 1978-12-26 | 1981-09-15 | E-Y Laboratories, Inc. | Immunological determination using lectin |
JPS56118672A (en) * | 1980-02-23 | 1981-09-17 | Ajinomoto Co Inc | Measuring method of antigen or antibody |
DE3425008A1 (de) * | 1984-07-06 | 1986-02-06 | Boehringer Mannheim Gmbh, 6800 Mannheim | Verfahren und vorrichtung zur durchfuehrung analytischer bestimmungen |
US4935339A (en) * | 1985-05-07 | 1990-06-19 | Nichols Institute Diagnostics | Delayed solid phase immunologic assay |
US4914040A (en) * | 1988-03-03 | 1990-04-03 | Boehringer Mannheim Gmbh | Reagent and method for determination of a polyvalent substance using an immunoaggregate |
-
1988
- 1988-08-29 DE DE3829245A patent/DE3829245A1/de not_active Withdrawn
-
1989
- 1989-08-22 US US07/396,860 patent/US5362655A/en not_active Expired - Lifetime
- 1989-08-22 AU AU40143/89A patent/AU607348B2/en not_active Ceased
- 1989-08-28 AT AT89115852T patent/ATE117433T1/de not_active IP Right Cessation
- 1989-08-28 ZA ZA896535A patent/ZA896535B/xx unknown
- 1989-08-28 ES ES89115852T patent/ES2068222T3/es not_active Expired - Lifetime
- 1989-08-28 EP EP89115852A patent/EP0356964B1/fr not_active Expired - Lifetime
- 1989-08-28 DE DE58908905T patent/DE58908905D1/de not_active Expired - Lifetime
- 1989-08-29 JP JP1220526A patent/JPH0765998B2/ja not_active Expired - Lifetime
- 1989-08-29 KR KR1019890012281A patent/KR920000056B1/ko not_active IP Right Cessation
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2013211A (en) * | 1978-01-26 | 1979-08-08 | Technicon Instr | Immunoassays using f(ab')2 fragments |
EP0138297A1 (fr) * | 1983-09-30 | 1985-04-24 | Becton Dickinson and Company | Suspensions de particules pour l'immuno - agglutination |
EP0147848A2 (fr) * | 1984-01-02 | 1985-07-10 | Roche Diagnostics GmbH | Méthode pour la détermination d'un antigèn polyvalent et réactif |
WO1988005913A1 (fr) * | 1987-01-29 | 1988-08-11 | Cytosignet, Inc. | Detection d'un analyte dans des echantillons contenant des particules |
US4829011A (en) * | 1987-08-27 | 1989-05-09 | Biotrack, Inc. | Agglutination assay |
Also Published As
Publication number | Publication date |
---|---|
AU607348B2 (en) | 1991-02-28 |
ATE117433T1 (de) | 1995-02-15 |
DE58908905D1 (de) | 1995-03-02 |
ZA896535B (en) | 1990-06-27 |
AU4014389A (en) | 1990-03-01 |
ES2068222T3 (es) | 1995-04-16 |
EP0356964B1 (fr) | 1995-01-18 |
KR920000056B1 (ko) | 1992-01-06 |
DE3829245A1 (de) | 1990-03-01 |
JPH0765998B2 (ja) | 1995-07-19 |
KR900003632A (ko) | 1990-03-26 |
EP0356964A2 (fr) | 1990-03-07 |
US5362655A (en) | 1994-11-08 |
JPH02107966A (ja) | 1990-04-19 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EP0356964A3 (fr) | Méthode pour la détermination d'une substance de liaison spécifique | |
EP0349988A3 (en) | Method to determine a specific substance capable of binding | |
CA2000545A1 (fr) | Procede et reactif pour la determination d'une substance pouvant etre particulierement liaisonnee | |
AU7044787A (en) | Internal references for use in analyte-receptor assays | |
CA2004878A1 (fr) | Appareil et methode pour le dosage sequentiel d'un produit a analyser dans un echantillon liquide | |
DE3587720D1 (de) | Testverfahren. | |
FI891012A (fi) | Menetelmä ja väline immuunikokeissa esiintyvien häiriötekijöiden kompensoimiseksi | |
EP0214847A3 (en) | Squarate dye conjugate, process for making it and its use in assay methods and kits | |
DE59410003D1 (de) | Synthetischer Standard für Immunoassays | |
EP0243655A3 (fr) | Procédé et réactif pour la détermination d'un partenaire réactionnel d'une réaction immunologique | |
ES2023868B3 (es) | Procedimiento de determinacion inmunometrico | |
EP0230934A3 (fr) | Anticorps monoclonal, procédé de mesure de protéine glucosylée utilisant cet anticorps monoclonal, et trousse à cet effet | |
EP0161107A3 (fr) | Méthode immunométrique pour la détermination d'un haptène | |
AU4440096A (en) | Competitive immunoassay using complexed analyte derivatives | |
EP0368208A3 (fr) | Méthode d'assai immunologique et trousse d'essai | |
AU7534287A (en) | Method for diagnostic immunoassay by solid phase separation | |
AU6205290A (en) | Method for the detection of analytes | |
EP0650054A3 (fr) | Procédé et dispositif d'obtention et de détection de substances réactives immunologiquement d'une phase gazeuse. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 19890828 |
|
AK | Designated contracting states |
Kind code of ref document: A2 Designated state(s): AT BE CH DE ES FR GB GR IT LI LU NL SE |
|
PUAL | Search report despatched |
Free format text: ORIGINAL CODE: 0009013 |
|
AK | Designated contracting states |
Kind code of ref document: A3 Designated state(s): AT BE CH DE ES FR GB GR IT LI LU NL SE |
|
17Q | First examination report despatched |
Effective date: 19921214 |
|
GRAA | (expected) grant |
Free format text: ORIGINAL CODE: 0009210 |
|
AK | Designated contracting states |
Kind code of ref document: B1 Designated state(s): AT BE CH DE ES FR GB GR IT LI LU NL SE |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: GR Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 19950118 |
|
REF | Corresponds to: |
Ref document number: 117433 Country of ref document: AT Date of ref document: 19950215 Kind code of ref document: T |
|
GBT | Gb: translation of ep patent filed (gb section 77(6)(a)/1977) |
Effective date: 19950128 |
|
REF | Corresponds to: |
Ref document number: 58908905 Country of ref document: DE Date of ref document: 19950302 |
|
ITF | It: translation for a ep patent filed | ||
REG | Reference to a national code |
Ref country code: ES Ref legal event code: FG2A Ref document number: 2068222 Country of ref document: ES Kind code of ref document: T3 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: SE Effective date: 19950418 |
|
ET | Fr: translation filed | ||
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: AT Payment date: 19950811 Year of fee payment: 7 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: GB Payment date: 19950817 Year of fee payment: 7 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: NL Payment date: 19950825 Year of fee payment: 7 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: LU Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 19950831 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: BE Payment date: 19951011 Year of fee payment: 7 |
|
PLBE | No opposition filed within time limit |
Free format text: ORIGINAL CODE: 0009261 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: NO OPPOSITION FILED WITHIN TIME LIMIT |
|
NLT2 | Nl: modifications (of names), taken from the european patent patent bulletin |
Owner name: BOEHRINGER MANNHEIM GMBH |
|
26N | No opposition filed | ||
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: AT Effective date: 19960828 Ref country code: GB Effective date: 19960828 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: BE Effective date: 19960831 |
|
BERE | Be: lapsed |
Owner name: BOEHRINGER MANNHEIM G.M.B.H. Effective date: 19960831 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: NL Effective date: 19970301 |
|
GBPC | Gb: european patent ceased through non-payment of renewal fee |
Effective date: 19960828 |
|
NLV4 | Nl: lapsed or anulled due to non-payment of the annual fee |
Effective date: 19970301 |
|
REG | Reference to a national code |
Ref country code: CH Ref legal event code: PFA Owner name: BOEHRINGER MANNHEIM GMBH Free format text: BOEHRINGER MANNHEIM GMBH#SANDHOFERSTRASSE 112-132 POSTFACH 31 01 20#D-68298 MANNHEIM (DE) -TRANSFER TO- BOEHRINGER MANNHEIM GMBH#SANDHOFERSTRASSE 112-132 POSTFACH 31 01 20#D-68298 MANNHEIM (DE) |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: DE Payment date: 20080829 Year of fee payment: 20 Ref country code: ES Payment date: 20080806 Year of fee payment: 20 Ref country code: CH Payment date: 20080708 Year of fee payment: 20 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: IT Payment date: 20080814 Year of fee payment: 20 Ref country code: FR Payment date: 20080807 Year of fee payment: 20 |
|
REG | Reference to a national code |
Ref country code: CH Ref legal event code: PL |
|
REG | Reference to a national code |
Ref country code: ES Ref legal event code: FD2A Effective date: 20090829 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: ES Free format text: LAPSE BECAUSE OF EXPIRATION OF PROTECTION Effective date: 20090829 |