EP0234471A3 - Pré-colonne chromatographique - Google Patents

Pré-colonne chromatographique Download PDF

Info

Publication number
EP0234471A3
EP0234471A3 EP87102162A EP87102162A EP0234471A3 EP 0234471 A3 EP0234471 A3 EP 0234471A3 EP 87102162 A EP87102162 A EP 87102162A EP 87102162 A EP87102162 A EP 87102162A EP 0234471 A3 EP0234471 A3 EP 0234471A3
Authority
EP
European Patent Office
Prior art keywords
column
chromatographic pre
chromatographic
sorbent filled
guard column
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP87102162A
Other languages
German (de)
English (en)
Other versions
EP0234471A2 (fr
Inventor
Stefan Dr. Wermuth
Günter Hauke
Klaus Kreher
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Patent GmbH
Original Assignee
Merck Patent GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent GmbH filed Critical Merck Patent GmbH
Publication of EP0234471A2 publication Critical patent/EP0234471A2/fr
Publication of EP0234471A3 publication Critical patent/EP0234471A3/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G01N30/6091—Cartridges
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/04—Preparation or injection of sample to be analysed
    • G01N30/06—Preparation
    • G01N30/08—Preparation using an enricher
    • G01N2030/085—Preparation using an enricher using absorbing precolumn
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G01N30/6004—Construction of the column end pieces
    • G01N30/6026—Fluid seals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G01N30/6004—Construction of the column end pieces
    • G01N30/603—Construction of the column end pieces retaining the stationary phase, e.g. Frits

Landscapes

  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
EP87102162A 1986-02-28 1987-02-16 Pré-colonne chromatographique Withdrawn EP0234471A3 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19863606474 DE3606474A1 (de) 1986-02-28 1986-02-28 Chromatographievorsaeule
DE3606474 1986-02-28

Publications (2)

Publication Number Publication Date
EP0234471A2 EP0234471A2 (fr) 1987-09-02
EP0234471A3 true EP0234471A3 (fr) 1989-05-10

Family

ID=6295125

Family Applications (1)

Application Number Title Priority Date Filing Date
EP87102162A Withdrawn EP0234471A3 (fr) 1986-02-28 1987-02-16 Pré-colonne chromatographique

Country Status (4)

Country Link
US (1) US4710289A (fr)
EP (1) EP0234471A3 (fr)
JP (1) JPS62206444A (fr)
DE (1) DE3606474A1 (fr)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2603990B1 (fr) * 1986-09-15 1988-12-16 Plastimarne Dispositif de detection d'analyse d'identification et de caracterisation par filtration et immunofiltration
DE3738691A1 (de) * 1987-11-13 1989-05-24 Chmiel Horst Verfahren und vorrichtung zur praeparativen fluessigkeitschromatographie bzw. adsorption
CN1040690C (zh) * 1992-09-03 1998-11-11 惠普公司 一种色谱用的固相提取柱
US5338448A (en) * 1992-10-16 1994-08-16 Sarasep, Inc. Method of preventing contamination of a chromatography column
US5667676A (en) * 1996-05-01 1997-09-16 Alaska; Andrew B. Side-packed chromatographic column
US5866008A (en) * 1997-02-11 1999-02-02 Shalon; Yehuda Method for packing and sealing chromatographic columns
US6036855A (en) * 1997-02-11 2000-03-14 Modcol Corporation Method and apparatus for packing and sealing chromatographic columns
US5893971A (en) * 1997-02-11 1999-04-13 Modcol Corporation Apparatus that maintains compression in a tube
US5863428A (en) * 1997-04-01 1999-01-26 Phenomenex Guard cartridge for chromatography
DE19718643C2 (de) * 1997-05-02 2000-02-24 Albin Maisch Chromatographievorsäule
US5951873A (en) * 1997-12-23 1999-09-14 Modcol Corporation Chromatographic device with piston locking mechanism and method of packing same
WO2002095390A1 (fr) * 2001-05-18 2002-11-28 Northwest University Colonne chromatographique remplie d'une substance tassee, son procede de production et ses applications
US20030205515A1 (en) * 2002-03-04 2003-11-06 Geoffrey Purdom Sanitary seal for modular chromatography columns
US6932904B2 (en) 2002-04-02 2005-08-23 Alltech Associates Inc. Chromatographic device and method of forming a chromatographic device
US7008532B2 (en) * 2002-04-12 2006-03-07 Alltech Associates Inc. Chromatographic device having an elongate rod and method of forming and chromatographic device
US6824678B2 (en) * 2003-02-06 2004-11-30 Robert D. Thompson Closure system for chromatography columns
GB2434556B (en) * 2004-08-19 2010-09-29 Waters Investments Ltd Devices, assemblies and systems for performing separations
US7563410B2 (en) * 2004-10-19 2009-07-21 Agilent Technologies, Inc. Solid phase extraction apparatus and method
US8377296B2 (en) * 2009-05-15 2013-02-19 Ge Healthcare Bio-Sciences Ab Filter holder in a chromatography column
EP2459291B1 (fr) * 2009-07-30 2018-03-14 F.Hoffmann-La Roche Ag Séparateur mobile de colonne de chromatographie
CN103339502B (zh) 2011-02-02 2016-02-17 霍夫曼-拉罗奇有限公司 色谱柱支撑体

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2930962A1 (de) * 1979-07-31 1981-02-19 Merck Patent Gmbh Chromatographiesaeule
FR2484858A1 (fr) * 1980-04-21 1981-12-24 Hitachi Chemical Co Ltd Avant-colonne et colonne a cartouche pour chromatographie en phase liquide
EP0068343A1 (fr) * 1981-06-19 1983-01-05 Ceskoslovenska akademie ved Colonne pour chromatographie liquide
DE3424787A1 (de) * 1983-07-07 1985-01-17 Ciba-Geigy Ag, Basel Saeule fuer die mitteldruck-fluessigchromatographie
US4565632A (en) * 1985-01-11 1986-01-21 Beckman Instruments, Inc. Chromatographic cartridge column system
DE8614341U1 (de) * 1986-05-27 1986-07-10 Merck Patent Gmbh, 6100 Darmstadt Chromatographievorsäule
EP0205002A1 (fr) * 1985-06-01 1986-12-17 MERCK PATENT GmbH Colonne chromatographique

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH465271A (de) * 1963-10-02 1968-11-15 Ceskoslovenska Akademie Ved Kolonnenverschluss für Säulenchromatograph
US3298527A (en) * 1965-05-17 1967-01-17 Wright John Lemon Chromatographic flow column
CH546088A (de) * 1971-12-07 1974-02-28 Merck Patent Gmbh Saeule fuer druck-chromatographie.
DE2626946A1 (de) * 1976-06-16 1977-12-29 Horst Krannich Saeulenkopf fuer die chromatographie in waessrigen und nichtwaessrigen loesungsmittelsystemen
US4283280A (en) * 1978-08-24 1981-08-11 Brownlee Labs, Inc. Cartridge type separation column and holder assembly for liquid chromatographs
US4309286A (en) * 1980-05-20 1982-01-05 Lenihan Jr Harry J Lower sealing means for chromatographic column
DE3021306A1 (de) * 1980-06-06 1981-12-24 Licentia Patent-Verwaltungs-Gmbh, 6000 Frankfurt Anordnung mit einem wenigstens zwei teilnehmern gemeinsamen datenspeicher
DE3143075A1 (de) * 1981-10-30 1983-05-11 Merck Patent Gmbh, 6100 Darmstadt Saeuleneinspannvorrichtung fuer die chromatographie"
ATE20829T1 (de) * 1982-04-28 1986-08-15 Duphar Int Res Vorsaeule zum vorkonzentrieren von durch chromatographie zu trennenden stoffen, sowie vorrichtung fuer ein fluessigkeitschromatographiesystem und kupplungsstueck fuer diese vorrichtung.
IL66551A (en) * 1982-08-15 1985-11-29 Cais Michael Method for moving-bed chromatography and device therefor
US4636316A (en) * 1985-01-11 1987-01-13 Beckman Instruments, Inc. Disposable column cartridge
US4655917A (en) * 1985-08-19 1987-04-07 Rainin Instrument Co. Modular liquid chromatography column apparatus

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2930962A1 (de) * 1979-07-31 1981-02-19 Merck Patent Gmbh Chromatographiesaeule
FR2484858A1 (fr) * 1980-04-21 1981-12-24 Hitachi Chemical Co Ltd Avant-colonne et colonne a cartouche pour chromatographie en phase liquide
EP0068343A1 (fr) * 1981-06-19 1983-01-05 Ceskoslovenska akademie ved Colonne pour chromatographie liquide
DE3424787A1 (de) * 1983-07-07 1985-01-17 Ciba-Geigy Ag, Basel Saeule fuer die mitteldruck-fluessigchromatographie
US4565632A (en) * 1985-01-11 1986-01-21 Beckman Instruments, Inc. Chromatographic cartridge column system
EP0205002A1 (fr) * 1985-06-01 1986-12-17 MERCK PATENT GmbH Colonne chromatographique
DE8614341U1 (de) * 1986-05-27 1986-07-10 Merck Patent Gmbh, 6100 Darmstadt Chromatographievorsäule

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
JOURNAL OF CHROMATOGRAPHY. Band 301, 1984, Seiten 325-334; C.E. GOEWIE et al.: "Optimization of Precolumn Design in Liquid Chromatography". *

Also Published As

Publication number Publication date
DE3606474A1 (de) 1987-09-17
JPS62206444A (ja) 1987-09-10
US4710289A (en) 1987-12-01
EP0234471A2 (fr) 1987-09-02

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RIN1 Information on inventor provided before grant (corrected)

Inventor name: KREHER, KLAUS

Inventor name: HAUKE, GUENTER

Inventor name: WERMUTH, STEFAN, DR.