EP0200579B1 - Vorrichtung zur Lagerung von Rohren in einem kryogenen Behälter - Google Patents

Vorrichtung zur Lagerung von Rohren in einem kryogenen Behälter Download PDF

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Publication number
EP0200579B1
EP0200579B1 EP86400479A EP86400479A EP0200579B1 EP 0200579 B1 EP0200579 B1 EP 0200579B1 EP 86400479 A EP86400479 A EP 86400479A EP 86400479 A EP86400479 A EP 86400479A EP 0200579 B1 EP0200579 B1 EP 0200579B1
Authority
EP
European Patent Office
Prior art keywords
tubes
drawer
drawers
liquid nitrogen
grating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
EP86400479A
Other languages
English (en)
French (fr)
Other versions
EP0200579A1 (de
Inventor
Daniel Delatte
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LAir Liquide SA pour lEtude et lExploitation des Procedes Georges Claude
Original Assignee
LAir Liquide SA pour lEtude et lExploitation des Procedes Georges Claude
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by LAir Liquide SA pour lEtude et lExploitation des Procedes Georges Claude filed Critical LAir Liquide SA pour lEtude et lExploitation des Procedes Georges Claude
Priority to AT86400479T priority Critical patent/ATE35048T1/de
Publication of EP0200579A1 publication Critical patent/EP0200579A1/de
Application granted granted Critical
Publication of EP0200579B1 publication Critical patent/EP0200579B1/de
Expired legal-status Critical Current

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Classifications

    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
    • F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
    • F25D25/00—Charging, supporting, and discharging the articles to be cooled
    • F25D25/005—Charging, supporting, and discharging the articles to be cooled using containers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L9/00—Supporting devices; Holding devices
    • B01L9/06—Test-tube stands; Test-tube holders

Definitions

  • the present invention relates to a device for storing in liquid nitrogen tubes having different stirrers, device of the type comprising a superposition of removable drawers sliding in a chassis, this chassis comprising at least one rack suitable for receiving at least two drawers . It applies in particular to the storage of biological products in liquid nitrogen.
  • the tubes intended for the cryogenic storage of biological products such as animal or human seeds normally have a standard diameter but different heights, corresponding to samples of 2 ml and 5 ml. It is therefore currently necessary to have two types of storage devices, one for each type of tube.
  • a known device of the aforementioned type, described in DE-A-2 528 152, is not suitable for immersion in liquid nitrogen, because if a drawer is removed, the tubes contained in the drawer located below are no longer held up.
  • the object of the invention is to provide a storage device offering great flexibility thanks to the possibility of storing simultaneously and in variable proportions in liquid nitrogen the two types of tubes.
  • the invention relates to a storage device of the aforementioned type, characterized in that the rack comprises a removable horizontal intermediate partition adapted to be placed between the two drawers and which, in this position, supports the upper drawer and retains the tubes contained in the lower drawer.
  • each drawer is provided, at an intermediate height, with a grid for positioning the tubes, this grid comprising, for each tube, a hole which can be freely traversed by it and surrounded by reliefs for lateral support of the tube. It is then advantageous that the grid is removable and rotatable.
  • the storage module 1 shown in the drawing is intended to hold a number of tubes 2, 3 for preserving biological products in a container (not shown) filled with liquid nitrogen.
  • a container not shown
  • several modules 1 are stacked and fixed to each other, for example by welding or clipping, to occupy the entire height of the container, the upper module being equipped with a handle.
  • the module 1 shown has, in plan, a rectangular shape, it can also have another shape, for example triangular, so that all the stacks of modules make the best use of the space available in the container.
  • the module 1 comprises a rack 4, two drawers 5 each equipped with a grid 6 (the upper drawer and the grids 6 have not been shown in FIG. 2, for the sake of clarity of the drawing), and a partition 7 All these elements are made of a plastic material adapted to withstand cryogenic temperatures.
  • the tubes 2 and 3 have a common diameter, but the tubes 3 have a height approximately twice that of the tubes 2. They are intended to store samples of 2 ml (tubes 2) and 5 ml (tubes 3) respectively.
  • the locker 4 is parallelepiped and open on its front face. Its upper and lower faces are full, and its three other faces largely perforated by pairs of windows 8 separated by horizontal members 9 located halfway up the rack. Each lateral member has an internal groove 10, and the rear member has a snap-in recess 11.
  • Each drawer 5 is open upwards. Its front face 12, of reduced height, has a central tab 13 for gripping. On its inner periphery, the drawer has a number of vertical ribs 14 extending approximately halfway up. Furthermore, although this is not shown, the drawer has at its bottom at least one opening for draining liquid nitrogen, and also external snap reliefs for keeping it in position in the rack.
  • each drawer Associated with each drawer is a grid 6, a corner of which is shown in FIG. 3.
  • This grid comprises a large number of circular trQUS 15 whose diameter is slightly greater than that of the tubes 2 and 3 - and, between these holes, a large number of cylindrical pins 16 arranged in a picot manner is slightly less than half that of a drawer.
  • the partition 7 is a rectangular plate, the lateral edges of which are adapted to slide in the grooves 10 of the rack and the rear edge of which has a latching relief 17 in the recess 11.
  • each tube 2 of 2 ml is socked.
  • the corresponding grid 6 is placed on the ribs 14, with the pins 16 facing downward, and the tubes 2 are placed in the hole 15.
  • each tube 2 is held in vertical position and can easily be grabbed by its upper part to be extracted.
  • the partition 7 is put in place, the lower drawer 5 is inserted under it, pressing on the lower bottom of the rack 4, and the upper drawer 5 is inserted above the partition, pressing on this one.
  • the height of the tubes is such that each rests on the bottom of the corresponding drawer and rises to a level slightly lower than the wall which surmounts it: the partition 7 for the lower tubes 2, the upper wall of the rack 4 for the upper 2 tubes.
  • the tubes 2 When all of the modules 1 are immersed in liquid nitrogen, the tubes 2 tend to float on this liquid and therefore to rise. They are retained vertically, one by the partition 7, the other by the upper wall of the crate, and laterally by the pins 16 (which, as a variant, could be replaced by cylindrical collars). It can be seen that one or the other of the drawers 5 can be extracted without disturbing the positioning of the tubes 2 of the other drawer, thanks to the double role of the partition 7: support of the upper drawer on the one hand, retained vertical of the lower tubes on the other hand.
  • the other mode of use of the module 1, used for the storage of tubes 3 of 5 ml, is illustrated in the right half of Figure 1: the upper drawer is removed, and the grid 6 of the lower drawer is supported on the ribs 14 of the latter, but this time with the pins 16 facing upwards.
  • the long tubes 3 are arranged in the holes 15 and extend from the bottom of the lower drawer to a location close to the upper wall of the rack 4. More precisely, the distance separating this wall from the upper end of the tubes 3 is significantly lower than that which separates the bottom of the drawer from the top of the pins 16.
  • the tubes 3 When the module is immersed in liquid nitrogen, the tubes 3 tend to float on this liquid and therefore to rise, but they are held vertically by the upper wall of the crate 4 and guided laterally by the pins 16. Thus, from again, the arrangement of the tubes is not disturbed.

Landscapes

  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Mechanical Engineering (AREA)
  • Thermal Sciences (AREA)
  • Combustion & Propulsion (AREA)
  • Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Filling Or Discharging Of Gas Storage Vessels (AREA)
  • Packages (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Sampling And Sample Adjustment (AREA)

Claims (4)

1. Vorrichtung zur Lagerung von Rohren (2, 3) in flüssigem Stickstoff, welche unterschiedliche Höhen haben, insbesondere zur Lagerung von biologischen Produkten in flüssigem Stickstoff, mit einem Schichten von herausziehbaren Schubladen (5), die in einem Gehäuse gleiten, welches mindestens ein Fachgestell (4) hat, welches zur Aufnahme von mindestens zwei Schubladen (5) geeignet ausgestaltet ist, dadurch gekennzeichnet, daß das Fachgestell eine horizontale, herausziehbare Zwischenwand (7) aufweist, die geeignet ist, um zwischen den zwei Schubladen (5) angeordnet zu werden, und die in dieser Position die obere Schublade stützt und die in der unteren Schublade enthaltenen Rohre hält.
2. Vorrichtung nach Anspruch 1, dadurch gekennzeichnet, daß jede Schublade (5) in einer Zwischenhöhe mit einem Gitter (6) zum Positionieren der Rohre (2, 3) versehen ist, wobei dieses Gitter für jedes Rohr ein Loch (15) hat, durch welches das Rohr frei hindurchgehen kann und welches durch erhabene Teile (16) zum seitlichen Halten des Rohres umgeben ist.
3. Vorrichtung nach Anspruch 2, dadurch gekennzeichnet, daß das Gitter (6) herausziehbar und zurückbewegbar ist.
4. Vorrichtung nach einem der Ansprüche 1 bis 3, dadurch gekennzeichnet, daß sie ein Schichten von Fachgestellen (4) aufweist, die aneinander befestigt sind, wobei das obere Fachgestell mit einem Griff versehen ist.
EP86400479A 1985-03-26 1986-03-07 Vorrichtung zur Lagerung von Rohren in einem kryogenen Behälter Expired EP0200579B1 (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AT86400479T ATE35048T1 (de) 1985-03-26 1986-03-07 Vorrichtung zur lagerung von rohren in einem kryogenen behaelter.

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8504458A FR2579733B1 (fr) 1985-03-26 1985-03-26 Dispositif de stockage de tubes dans un recipient cryogenique
FR8504458 1985-03-26

Publications (2)

Publication Number Publication Date
EP0200579A1 EP0200579A1 (de) 1986-11-05
EP0200579B1 true EP0200579B1 (de) 1988-06-08

Family

ID=9317575

Family Applications (1)

Application Number Title Priority Date Filing Date
EP86400479A Expired EP0200579B1 (de) 1985-03-26 1986-03-07 Vorrichtung zur Lagerung von Rohren in einem kryogenen Behälter

Country Status (8)

Country Link
US (1) US4665713A (de)
EP (1) EP0200579B1 (de)
AT (1) ATE35048T1 (de)
AU (1) AU576143B2 (de)
CA (1) CA1285780C (de)
DE (1) DE3660296D1 (de)
FR (1) FR2579733B1 (de)
ZA (1) ZA861973B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4023194A1 (de) * 1990-07-20 1992-01-23 Kodak Ag Vorrichtung mit mehreren einreihig angeordneten aufnahmen fuer mit fluessigkeit gefuellte behaelter
US5168725A (en) * 1990-08-24 1992-12-08 National Health Guard, Inc. Cryogenic storage of perishable fluids
FR2680658B1 (fr) * 1991-08-30 1993-11-19 Air Liquide Panier de rangement de boitiers individuels et conteneur cryogenique.
US20050029914A1 (en) * 2003-08-05 2005-02-10 Zhenming Wang Highly flexible and accessible freezer drawer rack
US7870748B2 (en) * 2005-02-25 2011-01-18 Byrne Kathleen H Method for controlled rate freezing and long term cryogenic storage
US8099967B2 (en) * 2008-04-10 2012-01-24 Yu Jia Portable rack carrier device and the method of use
US20090273259A1 (en) * 2008-04-30 2009-11-05 Newell Operating Company Mobile Storage Assembly
CN102213529B (zh) * 2011-06-03 2017-03-01 海尔集团公司 冰箱冷藏室结构和具有其的冰箱
KR102001929B1 (ko) * 2013-03-08 2019-10-01 엘지전자 주식회사 냉장고
CN110697220A (zh) * 2019-11-21 2020-01-17 江苏盐西新城教育产业项目开发有限公司 一种微生物实验专用器材存放装置
DE102019135693A1 (de) * 2019-12-23 2021-06-24 Aixinno Limited Aufbewahrungsvorrichtung für Pipettenspitzen
WO2021188646A1 (en) * 2020-03-17 2021-09-23 Nypro Inc. Fusion packaging
US20240016701A1 (en) * 2022-07-12 2024-01-18 Ats Automation Tooling Systems Inc. High-density sterile magazine

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US1665681A (en) * 1923-02-03 1928-04-10 Charles B Telling Ice-cream-brick container
US2988412A (en) * 1959-02-09 1961-06-13 Vue Chest Inc Stackable display case
US3151760A (en) * 1960-12-27 1964-10-06 Union Carbide Corp Container for the low temperature preservation of biological substances
US3113689A (en) * 1961-10-03 1963-12-10 Moussong Monika Clamping plates for small containers, particularly ampoules
US3184071A (en) * 1962-12-12 1965-05-18 Eastman Kodak Co Plastic case for containers
GB1058503A (en) * 1965-05-10 1967-02-15 Francis Greif Improvements in and relating to memorandum devices
US3306689A (en) * 1965-07-21 1967-02-28 Walter E Heller & Company Receptacle
US3379315A (en) * 1966-04-07 1968-04-23 Maryland Plastics Inc Test tube rack
US3362577A (en) * 1966-10-17 1968-01-09 Monroe J. Singer Beverage carriers
US3493873A (en) * 1966-11-22 1970-02-03 Electronic Associates Rate resolver circuitry with voltage limiting
US3593873A (en) * 1968-05-22 1971-07-20 Nl Wapen En Munitefabr Container for cylindrical articles
US3744665A (en) * 1971-06-14 1973-07-10 V Spoto Combination vial and test tube rack
BE788135A (fr) * 1971-08-30 1973-02-28 Union Carbide Corp Procede et dispositif de congelation rapide
US3940249A (en) * 1973-05-29 1976-02-24 Streck Laboratories, Inc. Laboratory testing procedure
DE2528152A1 (de) * 1975-06-24 1977-01-20 Ratiomed Gmbh Vorrichtung fuer die aufnahme von probetraegern
US4143764A (en) * 1976-09-20 1979-03-13 Moss Iii L Howard Shipper container for flasks
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DE2819678C2 (de) * 1978-05-05 1986-02-13 Stucki Kunststoffwerk Und Werkzeugbau Gmbh, 4902 Bad Salzuflen Transportkasten aus Kunststoff
FR2461216A1 (fr) * 1979-07-10 1981-01-30 Saelens Bernard Boites de rangement pour congelateurs
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US4377077A (en) * 1981-07-15 1983-03-22 Biotech Research Laboratories, Inc. Device and method for controlled freezing of cell cultures
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Also Published As

Publication number Publication date
EP0200579A1 (de) 1986-11-05
DE3660296D1 (en) 1988-07-14
ZA861973B (en) 1986-11-26
CA1285780C (fr) 1991-07-09
FR2579733B1 (fr) 1987-11-20
FR2579733A1 (fr) 1986-10-03
ATE35048T1 (de) 1988-06-15
AU576143B2 (en) 1988-08-11
US4665713A (en) 1987-05-19
AU5487186A (en) 1986-10-02

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