EP0105220B1 - Gerät zur Erzeugung von Bildern eines Untersuchungsobjektes mit magnetischer Kernresonanz - Google Patents

Gerät zur Erzeugung von Bildern eines Untersuchungsobjektes mit magnetischer Kernresonanz Download PDF

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Publication number
EP0105220B1
EP0105220B1 EP83108831A EP83108831A EP0105220B1 EP 0105220 B1 EP0105220 B1 EP 0105220B1 EP 83108831 A EP83108831 A EP 83108831A EP 83108831 A EP83108831 A EP 83108831A EP 0105220 B1 EP0105220 B1 EP 0105220B1
Authority
EP
European Patent Office
Prior art keywords
object under
under examination
calibration body
magnetic resonance
nuclear magnetic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
EP83108831A
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German (de)
English (en)
French (fr)
Other versions
EP0105220A1 (de
Inventor
Wilfried Dr. Loeffler
Arnulf Dr. Oppelt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Siemens AG
Original Assignee
Siemens AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Siemens AG filed Critical Siemens AG
Publication of EP0105220A1 publication Critical patent/EP0105220A1/de
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Publication of EP0105220B1 publication Critical patent/EP0105220B1/de
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/50—NMR imaging systems based on the determination of relaxation times, e.g. T1 measurement by IR sequences; T2 measurement by multiple-echo sequences
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/58—Calibration of imaging systems, e.g. using test probes, Phantoms; Calibration objects or fiducial markers such as active or passive RF coils surrounding an MR active material

Definitions

  • the invention relates to a device for generating images of an examination object with magnetic nuclear magnetic resonance, in which coils for applying magnetic fields to the examination object and for detecting the deflection of the atomic nuclei of the examination object from their equilibrium position are present by a high-frequency magnetic excitation pulse.
  • the hydrogen atom nuclei of an examination object can be deflected from a preferred direction, which is generated by a basic magnetic field, by means of a high-frequency excitation pulse, and that the atomic nuclei only spin back in after a certain time after the end of this excitation pulse level off the preferred direction.
  • the atomic nuclei precess at a frequency that depends on the strength of the basic magnetic field. If a field gradient is superimposed on this homogeneous basic magnetic field, so that the magnetic field distribution varies spatially, it is possible to locate the frequency measured in each case. It is also known that in this way and by changing the direction of the field gradient, slice images of the examination object can be made.
  • the excitation in one layer of the examination object takes place in that the basic magnetic field is influenced by a further field gradient in such a way that the atomic nuclei are only excited in this layer, because the excitation takes place only at a frequency that corresponds to the magnetic field in the desired one Layer is strictly assigned.
  • S is the measured signal and f is a function of the specified quantities, which varies depending on the measurement method.
  • p is the density and Tj, T 2 the relaxation times of the excited atomic nuclei.
  • c is a constant that characterizes the sensitivity of the apparatus.
  • the purpose of the present invention is to create a possibility for normalization and thus to compensate for the different sensitivity of the receiving coil and damping of the transmitting coil in a device of the type mentioned at the outset for the examination of patients.
  • this object is achieved in that the calibration body is designed in such a way that it at least partially encompasses the examination object during the measurement, so that it is at least partially cut by it during the measurement at each selected image plane.
  • a calibration body with defined values of p, T, and T 2 is attached to the edge of the measuring field, so that a simultaneous measurement of the examined layer and the calibration body and thus a normalization of the received signals is possible.
  • a calibration body expediently consists of aqueous solutions of a paramagnetic salt, the concentration of which can be used to set a tissue-like relaxation time.
  • the solutions are preferably located in tightly closed glass vessels to prevent evaporation of the water and thus a change in concentration.
  • the measurement values are advantageously corrected in such a way that the measured signal from the area of the calibration body serves as a measure of the sensitivity of the system and all measurement values from the area of the object to be recorded are converted to a constant sensitivity using a corresponding factor .
  • FIG. 1 shows a patient couch 2 mounted on a base 1 with a patient 3 who is in the interior of coils 4 of a device for generating images of an examination object magnetic resonance lies.
  • the coils 4 serve to apply magnetic fields to the patient 3 and to detect the deflection of the atomic nuclei of the patient 3 from their equilibrium position by means of a high-frequency magnetic excitation pulse. They are attached to a base 5.
  • FIG. 2 shows that a calibration body 6 is arranged in the interior of the coils 4 in such a way that it is at least partially cut by the patient 3 at each selected image plane when measuring the patient 3.
  • the calibration body 6 consists of three liquid-filled, straight, cylindrical glass tubes which are arranged at right angles to one another. This ensures for axial, coronary and sagittal layers that a glass tube is always cut through the examined plane.
  • the calibration body 7 shown in FIG. 3 consists of three liquid-filled curved glass tubes with a circular cross section and adapts to the spherical, usable measuring volume of the coils 4.
  • the levels spanned by the three curved tubes are perpendicular to each other. In this way, even with slice orientations that are rotated with respect to the axial, coronary and sagittal planes, it is ensured that a glass tube of the calibration body is always cut out at the edge of the measuring field under investigation and thus also measured.
  • FIG. 4 shows a calibration body 8 in the form of a liquid-filled, double-walled, cylindrical tube. This also ensures that areas of the calibration body are measured for all layer orientations and can thus be used for standardization.
  • the special measuring frequency used must be taken into account.
  • the effects of these errors on the functional dependency f, which are different for each measurement sequence, must be examined and suitable correction methods implemented. This is possible because the measured values of the calibration body allow the transmission coil damping to be calculated. It may be necessary to provide a subdivision of the calibration body into several chambers 9 (FIG. 5), which contain substances with different values for p, T, and T 2 , in order to allow an experimental separation of the receiver and transmitter coil damping.
  • Another advantage of the arrangement of a calibration body in the measuring field according to the invention is that a nuclear magnetic resonance signal can also be measured during the pauses in the examination, in which there is no patient in the measuring apparatus, in order, for example, to readjust the strength of the magnetic field accordingly.
  • the design of the calibration body according to FIG. 2 also makes it possible to distinguish which view of the measured layer is shown (from the front, back, top, bottom, right or left).

Landscapes

  • Physics & Mathematics (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • General Physics & Mathematics (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
EP83108831A 1982-09-22 1983-09-07 Gerät zur Erzeugung von Bildern eines Untersuchungsobjektes mit magnetischer Kernresonanz Expired EP0105220B1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3235113 1982-09-22
DE19823235113 DE3235113A1 (de) 1982-09-22 1982-09-22 Geraet zur erzeugung von bildern eines untersuchungsobjektes mit magnetischer kernresonanz

Publications (2)

Publication Number Publication Date
EP0105220A1 EP0105220A1 (de) 1984-04-11
EP0105220B1 true EP0105220B1 (de) 1986-05-14

Family

ID=6173881

Family Applications (1)

Application Number Title Priority Date Filing Date
EP83108831A Expired EP0105220B1 (de) 1982-09-22 1983-09-07 Gerät zur Erzeugung von Bildern eines Untersuchungsobjektes mit magnetischer Kernresonanz

Country Status (4)

Country Link
US (1) US4528510A (ja)
EP (1) EP0105220B1 (ja)
JP (1) JPS5964030A (ja)
DE (2) DE3235113A1 (ja)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0096487B1 (en) * 1982-06-09 1987-08-12 Picker International Limited Method and apparatus for monitoring movement of a body under nmr examination
NL8302721A (nl) * 1983-08-01 1985-03-01 Philips Nv Phantoom voor nmr apparatuur.
JPS60165951A (ja) * 1984-02-10 1985-08-29 株式会社東芝 磁気共鳴イメージング装置
GB8405065D0 (en) * 1984-02-27 1984-04-04 Picker Int Ltd Nuclear magnetic resonance imaging apparatus
JPS60222043A (ja) * 1984-04-20 1985-11-06 横河電機株式会社 核磁気共鳴による診断装置
IL72388A (en) * 1984-07-12 1988-07-31 Elscint Ltd Nmr imaging systems
US4618826A (en) * 1984-07-30 1986-10-21 U.K. Research Foundation Quality control phantom for use in computed tomographic imaging instruments and method of use
US4644276A (en) * 1984-09-17 1987-02-17 General Electric Company Three-dimensional nuclear magnetic resonance phantom
US4567894A (en) * 1984-11-09 1986-02-04 General Electric Company Hydraulically operated, mobile patient transport table useful with a magnetic resonance scanner
JPS61194338A (ja) * 1985-02-25 1986-08-28 Yokogawa Electric Corp 核磁気共鳴撮像装置の位相およびシエ−デイング補正方法
US4668915A (en) * 1985-03-15 1987-05-26 Honda Giken Kogyo Kabushiki Kaisha Non-uniform field magnetic resonance dual patient imaging system
DE3614142C2 (de) * 1985-04-26 1996-03-28 Toshiba Kawasaki Kk Verwendung eines Materials für die Diagnose durch Kernresonanz-Spektroskopie
US4716368A (en) * 1985-08-09 1987-12-29 Picker International, Inc. Magnetic resonance reconstruction and scanning techniques using known information, constraints, and symmetry relations
US4718431A (en) * 1985-10-22 1988-01-12 Siemens Aktiengesellschaft Surface coil with calibration substance for use in a nuclear magnetic resonance apparatus
JPS62153229A (ja) * 1985-12-27 1987-07-08 Nippon Oil Co Ltd 皮膚マ−カ−
US4769602A (en) * 1986-07-02 1988-09-06 Shell Oil Company Determining multiphase saturations by NMR imaging of multiple nuclides
IE61448B1 (en) * 1987-06-23 1994-11-02 Hafslund Nycomed Innovation Improvements in and relating to magnetic resonance imaging
WO1989004478A1 (en) * 1987-11-05 1989-05-18 University Of Queensland Magnetic field homogenization in nmr spectroscopy
JPH076765B2 (ja) * 1988-06-23 1995-01-30 株式会社日立メディコ 非破壊断面形状検査装置
US5178146A (en) * 1988-11-03 1993-01-12 Giese William L Grid and patient alignment system for use with MRI and other imaging modalities
US4888555A (en) * 1988-11-28 1989-12-19 The Board Of Regents, The University Of Texas Physiological phantom standard for NMR imaging and spectroscopy
US5603318A (en) 1992-04-21 1997-02-18 University Of Utah Research Foundation Apparatus and method for photogrammetric surgical localization
BE1007459A3 (nl) * 1993-08-24 1995-07-04 Philips Electronics Nv Magnetisch resonantie apparaat.
IT1282664B1 (it) * 1996-02-21 1998-03-31 Bracco Spa Dispositivo per la standardizzazione dell'intensita' di segnale nella tecnica di formazione di immagini a risonanza magnetica
EP1784654A1 (en) * 2004-08-25 2007-05-16 Philips Intellectual Property & Standards GmbH Mr method of determining local relaxation time values using calibrated phantom
RU2013121590A (ru) * 2010-10-13 2014-11-20 Конинклейке Филипс Электроникс Н.В. Фантом для мрт с множеством отделений для калибровки по т1

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0096487A1 (en) * 1982-06-09 1983-12-21 Picker International Limited Method and apparatus for monitoring movement of a body under NMR examination

Family Cites Families (9)

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GB1125481A (en) * 1964-09-07 1968-08-28 Newport Instr Ltd Improvements in or relating to methods and apparatus for examination and measurement by means of nuclear magnetic resonance phenomena
US3427532A (en) * 1966-02-14 1969-02-11 Varian Associates Nuclear magnetic resonance probe for spectrometers having an internal reference nuclei different than the nuclei under observation
US3501688A (en) * 1967-08-21 1970-03-17 Varian Associates Gyromagnetic resonance spectrometer programmed for automatic scan and calibration cycles
JPS5129678B1 (ja) * 1970-12-29 1976-08-26
US4050009A (en) * 1976-01-09 1977-09-20 The United States Of America As Represented By The Secretary Of The Army Spectrometer for external detection of magnetic and related double resonance
GB2037996B (en) * 1978-11-16 1983-07-20 Emi Ltd Imaging systems
GB2041537B (en) * 1979-01-25 1983-07-27 Emi Ltd Nmr Imaging systems
GB2043914B (en) * 1979-02-24 1982-12-22 Emi Ltd Imaging systems
JPS6051056B2 (ja) * 1980-06-13 1985-11-12 株式会社東芝 核磁気共鳴装置

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0096487A1 (en) * 1982-06-09 1983-12-21 Picker International Limited Method and apparatus for monitoring movement of a body under NMR examination

Also Published As

Publication number Publication date
US4528510A (en) 1985-07-09
JPS5964030A (ja) 1984-04-11
EP0105220A1 (de) 1984-04-11
DE3235113A1 (de) 1984-03-22
DE3363523D1 (en) 1986-06-19

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