EG24851A - Crystalline anticholinergic process for the preparation thereof for preparing a medicament - Google Patents

Crystalline anticholinergic process for the preparation thereof for preparing a medicament

Info

Publication number
EG24851A
EG24851A EG2002060698A EG2002060698A EG24851A EG 24851 A EG24851 A EG 24851A EG 2002060698 A EG2002060698 A EG 2002060698A EG 2002060698 A EG2002060698 A EG 2002060698A EG 24851 A EG24851 A EG 24851A
Authority
EG
Egypt
Prior art keywords
medicament
preparing
preparation
anticholinergic
crystalline
Prior art date
Application number
EG2002060698A
Other languages
English (en)
Inventor
Peter Sieger
Ulrike Werthmann
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Application granted granted Critical
Publication of EG24851A publication Critical patent/EG24851A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06—Oxygen atoms
    • C07D451/10—Oxygen atoms acylated by aliphatic or araliphatic carboxylic acids, e.g. atropine, scopolamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pulmonology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
EG2002060698A 2001-06-22 2002-06-19 Crystalline anticholinergic process for the preparation thereof for preparing a medicament EG24851A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10129710 2001-06-22
DE10215436 2002-04-08

Publications (1)

Publication Number Publication Date
EG24851A true EG24851A (en) 2010-10-27

Family

ID=26009556

Family Applications (1)

Application Number Title Priority Date Filing Date
EG2002060698A EG24851A (en) 2001-06-22 2002-06-19 Crystalline anticholinergic process for the preparation thereof for preparing a medicament

Country Status (37)

Country Link
EP (1) EP1401445B1 (enrdf_load_stackoverflow)
JP (1) JP2005504015A (enrdf_load_stackoverflow)
KR (2) KR101011353B1 (enrdf_load_stackoverflow)
CN (1) CN100586948C (enrdf_load_stackoverflow)
AR (1) AR037491A1 (enrdf_load_stackoverflow)
AT (1) ATE337006T1 (enrdf_load_stackoverflow)
AU (1) AU2002345016B2 (enrdf_load_stackoverflow)
BG (1) BG66303B1 (enrdf_load_stackoverflow)
BR (1) BR0210537A (enrdf_load_stackoverflow)
CA (1) CA2450961C (enrdf_load_stackoverflow)
CO (1) CO5550423A2 (enrdf_load_stackoverflow)
CY (1) CY1105223T1 (enrdf_load_stackoverflow)
CZ (1) CZ302786B6 (enrdf_load_stackoverflow)
DE (1) DE50207943D1 (enrdf_load_stackoverflow)
DK (1) DK1401445T3 (enrdf_load_stackoverflow)
EA (1) EA005813B1 (enrdf_load_stackoverflow)
EE (1) EE05316B1 (enrdf_load_stackoverflow)
EG (1) EG24851A (enrdf_load_stackoverflow)
ES (1) ES2271280T3 (enrdf_load_stackoverflow)
HR (1) HRP20031066B1 (enrdf_load_stackoverflow)
HU (1) HUP0400333A3 (enrdf_load_stackoverflow)
IL (2) IL159238A0 (enrdf_load_stackoverflow)
ME (1) ME00412B (enrdf_load_stackoverflow)
MX (1) MXPA03011718A (enrdf_load_stackoverflow)
MY (1) MY122779A (enrdf_load_stackoverflow)
NO (1) NO334301B1 (enrdf_load_stackoverflow)
NZ (1) NZ530690A (enrdf_load_stackoverflow)
PE (2) PE20030130A1 (enrdf_load_stackoverflow)
PL (1) PL208137B1 (enrdf_load_stackoverflow)
PT (1) PT1401445E (enrdf_load_stackoverflow)
RS (1) RS50441B (enrdf_load_stackoverflow)
SA (1) SA02230255B1 (enrdf_load_stackoverflow)
SI (1) SI1401445T1 (enrdf_load_stackoverflow)
SK (1) SK287262B6 (enrdf_load_stackoverflow)
TW (2) TW200617007A (enrdf_load_stackoverflow)
UY (1) UY27342A1 (enrdf_load_stackoverflow)
WO (1) WO2003000265A1 (enrdf_load_stackoverflow)

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DE102004048389A1 (de) 2004-10-01 2006-04-06 Boehringer Ingelheim Pharma Gmbh & Co. Kg Modifizierung von Oberflächen von Laktose als Hilfsstoff zur Verwendung für Pulverinhalativa
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KR20080012932A (ko) 2005-05-02 2008-02-12 베링거 인겔하임 인터내셔날 게엠베하 티오트로퓸 브로마이드의 신규한 결정형
DE102005030733A1 (de) 2005-07-01 2007-01-04 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Arzneimittelkombinationen zur Behandlung von Atemwegserkrankungen enthaltend langwirksame Beta-2-Agonisten und wenigstens einen weiteren Wirkstoff
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US20070086957A1 (en) * 2005-10-10 2007-04-19 Thierry Bouyssou Combination of medicaments for the treatment of respiratory diseases
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EP1847543A1 (de) 2006-04-19 2007-10-24 Boehringer Ingelheim Pharma GmbH & Co. KG Dihydrothienopyrimidine zur Behandlung von entzündlichen Erkrankungen
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WO2008017637A1 (de) 2006-08-07 2008-02-14 Boehringer Ingelheim International Gmbh Arzneimittelkombinationen zur behandlung von atemwegserkrankungen
UY30550A1 (es) 2006-08-22 2008-03-31 Boehringer Ingelheim Int Nuevos beta-agonistas enantioméricamente puros, procedimientos para su preparacion y su uso como medicamentos
GB0716026D0 (en) 2007-08-16 2007-09-26 Norton Healthcare Ltd An inhalable medicament
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EP2093219A1 (de) 2008-02-22 2009-08-26 Boehringer Ingelheim International Gmbh Kristalline, enantiomerenreine Salzform eines Betamimetikums und dessen Verwendung als Arzneimittel
PL2379525T3 (pl) 2008-12-19 2016-01-29 Centrexion Therapeutics Corp Cykliczne pirymidyno-4-karboksamidy jako antagoniści receptora CCR2 do leczenia stanów zapalnych, astmy oraz COPD
EP2403851B1 (en) 2009-03-06 2015-06-17 Mahmut Bilgic New crystalline forms of tiotropium bromide
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WO2011073155A1 (en) 2009-12-17 2011-06-23 Boehringer Ingelheim International Gmbh Novel antagonists for ccr2 and uses thereof
AU2011209274B8 (en) 2010-01-29 2015-08-13 Boehringer Ingelheim International Gmbh Substituted naphthyridines and their use as Syk kinase inhibitors
US8877745B2 (en) 2010-05-12 2014-11-04 Boehringer Ingelheim International Gmbh CCR2 receptor antagonists, method for producing the same, and use thereof as medicaments
EP2569295B1 (en) 2010-05-12 2014-11-19 Boehringer Ingelheim International GmbH New ccr2 receptor antagonists, method for producing the same, and use thereof as medicaments
US8841313B2 (en) 2010-05-17 2014-09-23 Boehringer Ingelheim International Gmbh CCR2 antagonists and uses thereof
WO2011147772A1 (en) 2010-05-25 2011-12-01 Boehringer Ingelheim International Gmbh Ccr2 receptor antagonists
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TR201007108A2 (tr) * 2010-08-25 2012-03-21 B�Lg�� Mahmut Yeni tiotropyum bromür kristali ve üretim yöntemi.@
EP2668177B1 (en) 2011-01-28 2014-10-22 Boehringer Ingelheim International GmbH Substituted pyridinyl-pyrimidines and their use as medicaments
TR201101897A2 (tr) 2011-02-28 2012-09-21 Bi̇lgi̇ç Mahmut Tiotropyum bromür içeren kristal madde
TR201102068A2 (tr) 2011-03-03 2012-09-21 Bi̇lgi̇ç Mahmut Tiotropyum bromür içeren kristal maddeler
TR201111589A2 (tr) * 2011-03-03 2012-09-21 Bi̇lgi̇ç Mahmut Tiotropyum bromür susuz kristal formu.
JP5786257B2 (ja) 2011-06-16 2015-09-30 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 新規の選択的ｃｃｒ２拮抗薬
JP5786258B2 (ja) 2011-07-15 2015-09-30 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 新規かつ選択的なｃｃｒ２拮抗薬
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CN106905314A (zh) 2011-11-25 2017-06-30 阿德弗里奥药品有限责任公司 用于制备取代的5‑氟‑1h‑吡唑并吡啶类化合物的方法
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Also Published As

Publication number Publication date
SI1401445T1 (sl) 2007-02-28
KR20040018285A (ko) 2004-03-02
EP1401445A1 (de) 2004-03-31
IL159238A (en) 2010-04-15
TWI261589B (en) 2006-09-11
CY1105223T1 (el) 2010-03-03
ATE337006T1 (de) 2006-09-15
MY122779A (en) 2006-05-31
EA200301293A1 (ru) 2004-08-26
CO5550423A2 (es) 2005-08-31
DE50207943D1 (de) 2006-10-05
NZ530690A (en) 2005-05-27
EA005813B1 (ru) 2005-06-30
CA2450961A1 (en) 2003-01-03
HUP0400333A3 (en) 2012-10-29
KR100971616B1 (ko) 2010-07-22
KR20090031638A (ko) 2009-03-26
RS50441B (sr) 2010-03-02
KR101011353B1 (ko) 2011-01-28
PL208137B1 (pl) 2011-03-31
ES2271280T3 (es) 2007-04-16
WO2003000265A1 (de) 2003-01-03
ME00412B (me) 2011-10-10
PE20030130A1 (es) 2003-04-02
PE20081305A1 (es) 2008-10-01
SK522004A3 (en) 2004-06-08
PL364489A1 (en) 2004-12-13
CN1520294A (zh) 2004-08-11
NO334301B1 (no) 2014-02-03
AU2002345016B2 (en) 2008-04-17
TW200617007A (en) 2006-06-01
HUP0400333A2 (hu) 2004-12-28
MXPA03011718A (es) 2004-12-06
EP1401445B1 (de) 2006-08-23
MEP62008A (en) 2011-05-10
BR0210537A (pt) 2004-06-22
DK1401445T3 (da) 2006-11-27
SK287262B6 (sk) 2010-04-07
EE200400029A (et) 2004-04-15
CZ302786B6 (cs) 2011-11-09
BG66303B1 (bg) 2013-03-29
CA2450961C (en) 2010-03-30
NO20035696D0 (no) 2003-12-19
PT1401445E (pt) 2006-10-31
IL159238A0 (en) 2004-06-01
HRP20031066B1 (en) 2011-10-31
CN100586948C (zh) 2010-02-03
YU99703A (sh) 2006-05-25
JP2005504015A (ja) 2005-02-10
HK1068540A1 (zh) 2005-04-29
SA02230255B1 (ar) 2006-10-31
UY27342A1 (es) 2003-02-28
AR037491A1 (es) 2004-11-17
BG108440A (bg) 2004-08-31
CZ2004120A3 (cs) 2004-05-12
HRP20031066A2 (en) 2004-04-30
EE05316B1 (et) 2010-08-16

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