EG20174A - Mixture of aliphatic alcohols of higher weight for treatment of hypercholesterolemia otheroesclerotic diseases and its obtention procedure from sugar cane wax - Google Patents

Mixture of aliphatic alcohols of higher weight for treatment of hypercholesterolemia otheroesclerotic diseases and its obtention procedure from sugar cane wax

Info

Publication number
EG20174A
EG20174A EG1493A EG1493A EG20174A EG 20174 A EG20174 A EG 20174A EG 1493 A EG1493 A EG 1493A EG 1493 A EG1493 A EG 1493A EG 20174 A EG20174 A EG 20174A
Authority
EG
Egypt
Prior art keywords
mixture
pct
hypercholesterolemia
treatment
aliphatic alcohols
Prior art date
Application number
EG1493A
Other languages
English (en)
Inventor
Abilio Laguna Grania
Original Assignee
Dalmer Lab Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dalmer Lab Sa filed Critical Dalmer Lab Sa
Application granted granted Critical
Publication of EG20174A publication Critical patent/EG20174A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/74Separation; Purification; Use of additives, e.g. for stabilisation
    • C07C29/88Separation; Purification; Use of additives, e.g. for stabilisation by treatment giving rise to a chemical modification of at least one compound
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/60Salicylic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/74Separation; Purification; Use of additives, e.g. for stabilisation
    • C07C29/76Separation; Purification; Use of additives, e.g. for stabilisation by physical treatment
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C31/00Saturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C31/02Monohydroxylic acyclic alcohols
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C31/00Saturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C31/02Monohydroxylic acyclic alcohols
    • C07C31/125Monohydroxylic acyclic alcohols containing five to twenty-two carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Reproductive Health (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)
  • Fats And Perfumes (AREA)
  • Medicinal Preparation (AREA)
EG1493A 1992-09-29 1993-01-09 Mixture of aliphatic alcohols of higher weight for treatment of hypercholesterolemia otheroesclerotic diseases and its obtention procedure from sugar cane wax EG20174A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CU92107A CU22229A1 (es) 1992-09-29 1992-09-29 Policosanol, una mezcla de alcoholes alifaticos primarios superiores para hipergregabilidad plaquetaria, los accidentes isquemicos, trombosis e incluso efectividad contra ulceras gastricas quimicamente inducidas y su proceso de obtencion de la caña de azucar. el tratamiento de complicaciones ateroscleroticas tales como la

Publications (1)

Publication Number Publication Date
EG20174A true EG20174A (en) 1997-08-31

Family

ID=5459372

Family Applications (1)

Application Number Title Priority Date Filing Date
EG1493A EG20174A (en) 1992-09-29 1993-01-09 Mixture of aliphatic alcohols of higher weight for treatment of hypercholesterolemia otheroesclerotic diseases and its obtention procedure from sugar cane wax

Country Status (19)

Country Link
US (2) US5663156A (fr)
EP (1) EP0619802B1 (fr)
JP (1) JP3602531B2 (fr)
KR (1) KR100269844B1 (fr)
CN (3) CN1736384B (fr)
AT (1) ATE172954T1 (fr)
AU (2) AU682462B2 (fr)
BR (1) BR9305652A (fr)
CA (1) CA2124578C (fr)
CU (1) CU22229A1 (fr)
DE (1) DE69321941T2 (fr)
DK (1) DK0619802T3 (fr)
EG (1) EG20174A (fr)
ES (1) ES2125973T3 (fr)
GR (1) GR3029280T3 (fr)
HK (2) HK1032356A1 (fr)
HU (2) HU0300408D0 (fr)
RU (1) RU2163229C2 (fr)
WO (1) WO1994007830A1 (fr)

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CU22412A1 (es) * 1993-11-09 1996-01-31 Dalmer Lab Sa Una mezcla natural compuesta por alcoholes alifaticos primarios superiores obtenidos de la cera de abejas para el tratamiento de las ulceras gastricas y duodenales que presenta tambien actividad antiinflamatoria
CU22723A1 (es) * 1997-04-02 2002-02-28 Dalmer Lab Sa Mezcla de ácidos grasos primarios de alto peso molecular obtenidos de la cera de cana de azúcar y sus usos farmacéuticos
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US6197832B1 (en) 1999-09-14 2001-03-06 Harlan Lee Sorkin, Jr. Composition for reducing serum cholesterol levels
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US7232574B1 (en) 1999-12-15 2007-06-19 Mcneil-Ppc, Inc. Long chain alcohols provided in edible oils
CN1091093C (zh) * 1999-12-30 2002-09-18 广东省食品工业研究所 高级脂肪醇脂肪酸酯及其用途
CN1100744C (zh) * 2000-04-30 2003-02-05 雷少华 一种由蔗蜡制取高级脂肪伯醇混合物的方法
US20030054978A1 (en) * 2001-08-31 2003-03-20 Babish John G. Arginine compositions for coordinate modification of multiple cardiovascular risk factors
US6683116B1 (en) * 2003-01-31 2004-01-27 Unigen Pharmaceuticals, Inc. Polycosanols from Ericerus pela wax
EP1503632A1 (fr) * 2002-05-02 2005-02-09 Volker Kuellmer Phytochimiques enrobes et agglomeres
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US7214394B2 (en) * 2002-05-31 2007-05-08 Archer-Daniels-Midland Company Policosanol compositions, extraction from novel sources, and uses thereof
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KR100590620B1 (ko) * 2002-09-13 2006-06-19 박유석 화분으로부터 고급알콜을 제조하는 방법
US20060127449A1 (en) * 2003-01-28 2006-06-15 Hargrove James L Method and composition for lowering cholesterol
US7034060B2 (en) * 2003-01-31 2006-04-25 Unigen Pharmaceuticals, Inc. Polycosanols from Ericerus pela wax
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US20050074443A1 (en) * 2003-10-03 2005-04-07 Treadwell Benjamin V. Methods of attenuating autoimmune disease and compositions useful therefor
US6890941B1 (en) * 2003-12-03 2005-05-10 Procaps S.A. Compositions containing HMG Co-A reductase inhibitors and policosanol
AP2006003832A0 (en) * 2004-01-20 2006-12-31 Panacea Biotec Ltd Pharmaceutical compositions comprising higher primary alcohols and ezetimibe and process of preparation thereof
AP2006003834A0 (en) * 2004-01-20 2006-12-31 Panacea Biotec Ltd Novel compositions comprising higher primary alcohols and nicottinic acid and process of preparationthereof
US20050267091A1 (en) * 2004-05-25 2005-12-01 Roger Berlin Compositions containing policosanol and niacin and/or niacin derivatives and their pharmaceutical uses
US20050267197A1 (en) * 2004-05-25 2005-12-01 Roger Berlin Compositions containing policosanol and HMG-Co-A reductase inhibitor and their pharmaceutical uses
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US20060020044A1 (en) * 2004-07-26 2006-01-26 Roger Berlin Methods and compositions for treating or preventing macular-degeneration related disorders
US20060020043A1 (en) * 2004-07-26 2006-01-26 Roger Berlin Methods and compositions for reducing C-reactive protein
US20060025486A1 (en) * 2004-07-27 2006-02-02 Roger Berlin Compositions containing policosanol and B vitamins and their pharmaceutical uses
US20060024383A1 (en) * 2004-07-27 2006-02-02 Roger Berlin Compositions containing policosanol and chromium and/or chromium salts and their pharmaceutical uses
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CN102795960B (zh) * 2012-08-08 2015-04-22 湖州圣涛生物技术有限公司 一种高纯度二十八烷醇、三十烷醇的规模化制备方法
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CN104557458A (zh) * 2014-12-24 2015-04-29 宜宾学院 一种从青蒿素生产废弃物中提取二十八烷醇的方法
CN106187677B (zh) * 2016-07-19 2019-03-26 北京颐方生物科技有限公司 一种以蔗蜡制备高级脂肪伯醇混合物的方法及应用
CN107332573B (zh) * 2017-07-25 2021-04-13 Oppo广东移动通信有限公司 一种射频电路、天线装置及电子设备
CN110108815B (zh) * 2019-05-24 2022-01-04 江西省科学院生物资源研究所 一种用于二十八烷醇预防肝损伤效果的体外评价方法
CU24638B1 (es) * 2020-02-03 2023-01-16 Centro Nac De Investigaciones Cientificas Suspensión oral con efecto antiulceroso y quimioprotector sobre el cáncer de colon
CN112716923B (zh) * 2021-01-13 2023-03-17 河北康泰药业有限公司 一种二十八元醇在制备治疗肺纤维化药物中的应用
CN113057941B (zh) * 2021-03-26 2022-06-17 中国林业科学研究院资源昆虫研究所 一种改善学习记忆的高级烷醇脂质体及其制备方法
CU20210060A7 (es) 2021-07-13 2023-02-13 Centro Nac De Investigaciones Cientificas Mezcla de compuestos con altos pesos moleculares, obtenida a partir de la cera de caña de azúcar (saccharum officinarum l.)
IT202100020228A1 (it) 2021-07-29 2023-01-29 Chromaleont Srl Metodo per l’estrazione di policosanoli da canapa industriale e relativa miscela.
CN115414333A (zh) * 2022-05-31 2022-12-02 湖北中古生物制药有限公司 一种多廿烷醇阿司匹林复方制剂及其制备方法

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Also Published As

Publication number Publication date
HU0300408D0 (en) 2003-04-28
US5856316A (en) 1999-01-05
CN1201731C (zh) 2005-05-18
CU22229A1 (es) 1996-01-31
CN1736384A (zh) 2006-02-22
CN1084844A (zh) 1994-04-06
BR9305652A (pt) 1996-11-19
DK0619802T3 (da) 1999-07-19
JP3602531B2 (ja) 2004-12-15
CA2124578C (fr) 2003-12-16
EP0619802A1 (fr) 1994-10-19
ES2125973T3 (es) 1999-03-16
WO1994007830A1 (fr) 1994-04-14
JPH07505414A (ja) 1995-06-15
AU711756B2 (en) 1999-10-21
CA2124578A1 (fr) 1994-04-14
HUT67607A (en) 1995-04-28
KR100269844B1 (ko) 2000-10-16
HK1087935A1 (en) 2006-10-27
CN1271577A (zh) 2000-11-01
US5663156A (en) 1997-09-02
CN1736384B (zh) 2010-05-26
GR3029280T3 (en) 1999-05-28
AU3493993A (en) 1994-04-26
DE69321941D1 (de) 1998-12-10
EP0619802B1 (fr) 1998-11-04
HU225050B1 (en) 2006-05-29
AU682462B2 (en) 1997-10-09
ATE172954T1 (de) 1998-11-15
AU5109298A (en) 1998-03-26
DE69321941T2 (de) 1999-06-10
HU9401938D0 (en) 1994-09-28
RU2163229C2 (ru) 2001-02-20
HK1032356A1 (en) 2001-07-20

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