EE200300519A - Meetod pioglitasooni kui suhkurtõvevastase aine saamiseks - Google Patents

Meetod pioglitasooni kui suhkurtõvevastase aine saamiseks

Info

Publication number
EE200300519A
EE200300519A EEP200300519A EEP200300519A EE200300519A EE 200300519 A EE200300519 A EE 200300519A EE P200300519 A EEP200300519 A EE P200300519A EE P200300519 A EEP200300519 A EE P200300519A EE 200300519 A EE200300519 A EE 200300519A
Authority
EE
Estonia
Prior art keywords
sup
formula
group
residue
general formula
Prior art date
Application number
EEP200300519A
Other languages
English (en)
Inventor
Halama Ales
Hejtm�nkov� Ludmila
Lustig Petr
Richter Jindrich
Srsnov� Lucie
Jirman Josef
Original Assignee
L�civa, a.s.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CZ20011501A external-priority patent/CZ20011501A3/cs
Priority claimed from CZ20011502A external-priority patent/CZ291364B6/cs
Application filed by L�civa, a.s. filed Critical L�civa, a.s.
Publication of EE200300519A publication Critical patent/EE200300519A/et

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Endocrinology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Saccharide Compounds (AREA)
EEP200300519A 2001-04-26 2002-04-25 Meetod pioglitasooni kui suhkurtõvevastase aine saamiseks EE200300519A (et)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CZ20011501A CZ20011501A3 (cs) 2001-04-26 2001-04-26 Způsob výroby meziproduktu pro výrobu antidiabetika
CZ20011502A CZ291364B6 (cs) 2001-04-26 2001-04-26 Způsob výroby antidiabetika
PCT/CZ2002/000024 WO2002088120A1 (en) 2001-04-26 2002-04-25 Method for obtaining pioglitazone as an antidiabetic agent

Publications (1)

Publication Number Publication Date
EE200300519A true EE200300519A (et) 2004-02-16

Family

ID=25746959

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200300519A EE200300519A (et) 2001-04-26 2002-04-25 Meetod pioglitasooni kui suhkurtõvevastase aine saamiseks

Country Status (11)

Country Link
US (1) US7009057B2 (et)
EP (1) EP1387843B1 (et)
AT (1) ATE355286T1 (et)
AU (1) AU2002311057A1 (et)
DE (1) DE60218449D1 (et)
EE (1) EE200300519A (et)
HU (1) HUP0400091A2 (et)
PL (1) PL363738A1 (et)
RU (1) RU2281285C2 (et)
SK (1) SK14452003A3 (et)
WO (1) WO2002088120A1 (et)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003272072A1 (en) 2002-07-16 2004-02-02 Cadila Healthcare Limited A process to prepare pioglitazone via several intermediates.
US8993773B2 (en) 2002-07-16 2015-03-31 Cadila Healthcare Limited Process to prepare pioglitazone via several novel intermediates
WO2004108721A1 (en) * 2003-04-01 2004-12-16 Sun Pharmaceutical Industries Limited Process for the preparation of 5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl] methyl]-2,4-thiazolidinedione
ES2219180B1 (es) 2003-05-09 2006-03-01 Medichem, S.A. Compuesto intermedio util para la preparacion de pioglitazona.
US7230016B2 (en) 2003-05-13 2007-06-12 Synthon Ip Inc. Pioglitazone salts, such as pioglitazone sulfate, and pharmaceutical compositions and processes using the same
US20050059708A1 (en) * 2003-05-13 2005-03-17 Karel Pospisilik Processes for making thiazolidinedione derivatives and compounds thereof
WO2005021542A2 (en) * 2003-08-28 2005-03-10 Ranbaxy Laboratories Limited Process for the preparation of pioglitazone
CN1319956C (zh) * 2003-09-12 2007-06-06 深圳市海粤门生物科技开发有限公司 一种噻唑烷二酮的衍生物及其药用制剂的制备方法和应用
EP1716144A2 (en) * 2004-02-20 2006-11-02 Synthon B.V. Processes for making pioglitazone and compounds of the processes
US7402713B2 (en) * 2006-03-07 2008-07-22 E.I. Du Pont De Nemours And Company Processes for conversion of tyrosine to p-hydroxystyrene and p-acetoxystyrene
PL2902026T3 (pl) 2006-03-16 2018-03-30 Metabolic Solutions Development Company Llc Analogi tiazolidynodionu do leczenia choroby metabolicznej pośredniczonej przez zapalenie
ES2388555T3 (es) 2006-03-16 2012-10-16 Metabolic Solutions Development Company Llc Análogos de tiazolidindiona
KR100791400B1 (ko) 2006-09-06 2008-01-07 동우신테크 주식회사 티아졸리딘디온 유도체의 제조방법
US8304441B2 (en) 2007-09-14 2012-11-06 Metabolic Solutions Development Company, Llc Thiazolidinedione analogues for the treatment of metabolic diseases
KR101537830B1 (ko) 2007-09-14 2015-07-17 메타볼릭 솔루션스 디벨롭먼트 컴퍼니, 엘엘씨 고혈압 치료용 티아졸리딘디온 유사체
WO2009148195A1 (en) * 2008-06-02 2009-12-10 Daebong Ls, Ltd. 5-(4-hydroxybenzyl)thiazolidine-2,4-dione as intermediate for synthesis of thiazolidinedione based compounds and process for preparing the same
WO2011084453A1 (en) 2009-12-15 2011-07-14 Metabolic Solutions Development Company Ppar-sparing thiazolidinedione salts for the treatment of metabolic diseases
CN108003090A (zh) * 2018-01-05 2018-05-08 白银亿尔精细化工有限公司 一种制备4-[2-(5-乙基-2-吡啶基)乙氧基]硝基苯的方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57209274A (en) * 1981-06-16 1982-12-22 Takeda Chem Ind Ltd Urea derivative, its preparation and its use
AR240698A1 (es) * 1985-01-19 1990-09-28 Takeda Chemical Industries Ltd Procedimiento para preparar compuestos de 5-(4-(2-(5-etil-2-piridil)-etoxi)benzil)-2,4-tiazolidindiona y sus sales
JPS62205054A (ja) * 1986-03-05 1987-09-09 Takeda Chem Ind Ltd 尿素誘導体
US5952509A (en) * 1996-06-27 1999-09-14 Takeda Chemical Industries, Ltd. Production of benzaldehyde compounds
JP4316787B2 (ja) * 2000-01-11 2009-08-19 壽製薬株式会社 エーテル又はアミド誘導体、その製法並びにそれを含有する糖尿病治療剤、

Also Published As

Publication number Publication date
ATE355286T1 (de) 2006-03-15
WO2002088120A1 (en) 2002-11-07
DE60218449D1 (de) 2007-04-12
EP1387843B1 (en) 2007-02-28
US20050043360A1 (en) 2005-02-24
AU2002311057A1 (en) 2002-11-11
SK14452003A3 (sk) 2004-04-06
EP1387843A1 (en) 2004-02-11
HUP0400091A2 (hu) 2004-06-28
US7009057B2 (en) 2006-03-07
WO2002088120B1 (en) 2004-02-26
RU2281285C2 (ru) 2006-08-10
RU2003134542A (ru) 2005-06-10
PL363738A1 (en) 2004-11-29

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