EE200200564A - Stavudiini sisaldavad toimeainet aeglustatult vabastavad graanulid - Google Patents

Stavudiini sisaldavad toimeainet aeglustatult vabastavad graanulid

Info

Publication number
EE200200564A
EE200200564A EEP200200564A EEP200200564A EE200200564A EE 200200564 A EE200200564 A EE 200200564A EE P200200564 A EEP200200564 A EE P200200564A EE P200200564 A EEP200200564 A EE P200200564A EE 200200564 A EE200200564 A EE 200200564A
Authority
EE
Estonia
Prior art keywords
sustained
granules containing
release granules
stavudine
containing stavudine
Prior art date
Application number
EEP200200564A
Other languages
English (en)
Estonian (et)
Inventor
Abramowitz Rober
M. O'donoghue Denise
B. Jain Nemichand
Original Assignee
Bristol-Myers Squibb Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol-Myers Squibb Company filed Critical Bristol-Myers Squibb Company
Publication of EE200200564A publication Critical patent/EE200200564A/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • A61K31/7072Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1617Organic compounds, e.g. phospholipids, fats
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Biophysics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
EEP200200564A 2000-03-30 2001-03-29 Stavudiini sisaldavad toimeainet aeglustatult vabastavad graanulid EE200200564A (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19358800P 2000-03-30 2000-03-30
PCT/US2001/010078 WO2001074329A2 (en) 2000-03-30 2001-03-29 Sustained release beadlets containing stavudine

Publications (1)

Publication Number Publication Date
EE200200564A true EE200200564A (et) 2004-06-15

Family

ID=22714247

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200200564A EE200200564A (et) 2000-03-30 2001-03-29 Stavudiini sisaldavad toimeainet aeglustatult vabastavad graanulid

Country Status (26)

Country Link
US (1) US7135465B2 (cs)
EP (1) EP1267879A2 (cs)
JP (1) JP2003528905A (cs)
KR (1) KR20030011805A (cs)
CN (1) CN1187052C (cs)
AR (1) AR027748A1 (cs)
AU (1) AU2001249591A1 (cs)
BG (1) BG107157A (cs)
BR (1) BR0109602A (cs)
CA (1) CA2404687A1 (cs)
CZ (1) CZ20023003A3 (cs)
EE (1) EE200200564A (cs)
GE (1) GEP20043285B (cs)
HU (1) HUP0302631A2 (cs)
IL (1) IL151475A0 (cs)
LT (1) LT5045B (cs)
LV (1) LV12939B (cs)
MX (1) MXPA02009534A (cs)
NO (1) NO20024645D0 (cs)
NZ (1) NZ522250A (cs)
PE (1) PE20011179A1 (cs)
PL (1) PL366089A1 (cs)
RU (1) RU2239435C2 (cs)
SK (1) SK12822002A3 (cs)
WO (1) WO2001074329A2 (cs)
ZA (1) ZA200207760B (cs)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY169670A (en) 2003-09-03 2019-05-08 Tibotec Pharm Ltd Combinations of a pyrimidine containing nnrti with rt inhibitors
US20060153908A1 (en) * 2002-06-27 2006-07-13 Brian Strong Spherical pellet formulations
EP2112920B1 (en) 2003-06-26 2018-07-25 Intellipharmaceutics Corp. Proton pump-inhibitor-containing capsules which comprise subunits differently structured for a delayed release of the active ingredient
US8394409B2 (en) 2004-07-01 2013-03-12 Intellipharmaceutics Corp. Controlled extended drug release technology
US20060024361A1 (en) * 2004-07-28 2006-02-02 Isa Odidi Disintegrant assisted controlled release technology
US10624858B2 (en) 2004-08-23 2020-04-21 Intellipharmaceutics Corp Controlled release composition using transition coating, and method of preparing same
CN100548309C (zh) * 2004-11-24 2009-10-14 东北制药总厂 司他夫定缓释片剂
TWI457136B (zh) 2005-04-04 2014-10-21 Tibotec Pharm Ltd Hiv-感染之預防
EP1898890A1 (en) * 2005-06-16 2008-03-19 Forest Laboratories, Inc. Modified and immediate release memantine bead formulation
AU2006286314A1 (en) * 2005-08-31 2007-03-08 Cipla Limited Pharmaceutical combinations containing lamivudine, stavudine and nevirapine
GB0525461D0 (en) 2005-12-15 2006-01-25 Archimedes Dev Ltd Pharmaceutical compositions
US10064828B1 (en) 2005-12-23 2018-09-04 Intellipharmaceutics Corp. Pulsed extended-pulsed and extended-pulsed pulsed drug delivery systems
EA014914B1 (ru) 2006-01-20 2011-02-28 Тиботек Фармасьютикалз Лтд. Долговременное лечение вич-инфекции
CN104825397A (zh) 2006-04-03 2015-08-12 伊萨·奥迪迪 含有机溶胶涂层的受控释放递送物件
EP2010162A4 (en) * 2006-04-03 2013-01-09 Isa Odidi COMPOSITION FOR DISPOSING A MEDICINAL PRODUCT
US10960077B2 (en) 2006-05-12 2021-03-30 Intellipharmaceutics Corp. Abuse and alcohol resistant drug composition
CL2008000746A1 (es) 2007-03-14 2008-09-22 Tibotec Pharm Ltd Composicion farmaceutica en solucion que comprende tmc278 y un polimero soluble en agua; proceso de preparacion de dicha composicion; y uso de un polvo que comprende tmc278 para tratar sida.
CN102319181B (zh) * 2011-09-08 2014-07-16 广东大华农动物保健品股份有限公司 一种微囊型动物药品的包被工艺
US20140271893A1 (en) * 2013-03-15 2014-09-18 Mcneil-Ppc, Inc. Coated phenylephrine particles and use thereof in pharmaceutical formulations
EP3169314A1 (en) * 2014-07-17 2017-05-24 Dow Global Technologies LLC Ethylcellulose dispersion and film
CN105511174A (zh) * 2016-01-05 2016-04-20 深圳市华星光电技术有限公司 液晶显示面板和显示装置

Family Cites Families (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4671963A (en) 1983-10-28 1987-06-09 Germino Felix J Stearate treated food products
US4670270A (en) 1984-05-07 1987-06-02 Germino Felix J Stearate treated food products
US4940556A (en) 1986-01-30 1990-07-10 Syntex (U.S.A.) Inc. Method of preparing long acting formulation
US4978655A (en) * 1986-12-17 1990-12-18 Yale University Use of 3'-deoxythymidin-2'-ene (3'deoxy-2',3'-didehydrothymidine) in treating patients infected with retroviruses
GB8707421D0 (en) * 1987-03-27 1987-04-29 Wellcome Found Pharmaceutical formulations
DE69231499T2 (de) 1991-12-30 2001-05-03 Fmc Corp., Philadelphia Zusammensetzung auf der basis von mikrokristalliner zellulose für die herstellung von kugelförmigen teilchen
US5472711A (en) 1992-07-30 1995-12-05 Edward Mendell Co., Inc. Agglomerated hydrophilic complexes with multi-phasic release characteristics
US5723490A (en) 1992-09-08 1998-03-03 Vertex Pharmaceuticals Incorporated THF-containing sulfonamide inhibitors of aspartyl protease
FI101039B (fi) 1992-10-09 1998-04-15 Eeva Kristoffersson Menetelmä lääkepellettien valmistamiseksi
US5869097A (en) 1992-11-02 1999-02-09 Alza Corporation Method of therapy comprising an osmotic caplet
GB9403449D0 (en) 1994-02-23 1994-04-13 Wellcome Found Therapeutic benzonitriles
JPH10500938A (ja) 1994-03-07 1998-01-27 バーテックス ファーマシューティカルズ インコーポレイテッド アスパラチルプロテアーゼインヒビターとしてのスルホンアミド誘導体
GB9417249D0 (en) * 1994-08-26 1994-10-19 Wellcome Found A novel salt
AU702422B2 (en) 1995-02-23 1999-02-18 Janssen Pharmaceutica N.V. Use of fused benzothiazoles as neuroprotectants
US6177460B1 (en) 1995-04-12 2001-01-23 The Procter & Gamble Company Method of treatment for cancer or viral infections
US5691372A (en) 1995-04-19 1997-11-25 Vertex Pharmaceuticals Incorporated Oxygenated-Heterocycle containing sulfonamide inhibitors of aspartyl protease
US5914332A (en) 1995-12-13 1999-06-22 Abbott Laboratories Retroviral protease inhibiting compounds
NZ501172A (en) 1995-12-15 2000-04-28 Cyropreservation Technologies Composition for organ cryopreservation comprising substituted amides
SE9600072D0 (sv) 1996-01-08 1996-01-08 Astra Ab New oral formulation of two active ingredients II
US5883252A (en) 1996-01-26 1999-03-16 Vertex Pharmaceuticals Incorporated Aspartyl protease inhibitors
US5766623A (en) 1996-03-25 1998-06-16 State Of Oregon Acting By And Through The Oregon State Board Of Higher Education On Behalf Of Oregon State University Compactable self-sealing drug delivery agents
US5849911A (en) 1996-04-22 1998-12-15 Novartis Finance Corporation Antivirally active heterocyclic azahexane derivatives
US5780055A (en) 1996-09-06 1998-07-14 University Of Maryland, Baltimore Cushioning beads and tablet comprising the same capable of forming a suspension
US5905068A (en) 1996-09-24 1999-05-18 Abbott Laboratories Retroviral protease inhibiting compounds
DE69735002T2 (de) 1996-10-25 2006-10-26 Shire Laboratories, Inc. Osmotisches Verabreichungssystem für lösliche Dosen
US5962462A (en) 1996-12-13 1999-10-05 Merck & Co., Inc. Spiro-substituted azacycles as modulators of chemokine receptor activity
US5919776A (en) 1996-12-20 1999-07-06 Merck & Co., Inc. Substituted aminoquinolines as modulators of chemokine receptor activity
US6124319A (en) 1997-01-21 2000-09-26 Merck & Co., Inc. 3,3-disubstituted piperidines as modulators of chemokine receptor activity
US6136827A (en) 1997-07-25 2000-10-24 Merck & Co., Inc. Cyclic amine modulations of chemokine receptor activity
WO1999007342A1 (en) 1997-08-11 1999-02-18 Alza Corporation Prolonged release active agent dosage form adapted for gastric retention
US6166037A (en) 1997-08-28 2000-12-26 Merck & Co., Inc. Pyrrolidine and piperidine modulators of chemokine receptor activity
DE69828635T2 (de) * 1997-09-19 2005-06-16 Shire Laboratories, Inc. Feste lösungskügelchen
US5904937A (en) 1997-10-03 1999-05-18 Fmc Corporation Taste masked pharmaceutical compositions
US6180634B1 (en) 1997-11-13 2001-01-30 Merck & Co., Inc. Combination therapy for the treatment of AIDS
US6013644A (en) 1997-12-12 2000-01-11 Merck & Co., Inc. Spiro-substituted azacycles as modulators of chemokine receptor activity
US6172061B1 (en) 1997-12-19 2001-01-09 Takeda Chemical Industries, Ltd. Pharmaceutical composition for antagonizing CCR5 comprising anilide derivative
US6140349A (en) 1998-02-02 2000-10-31 Merck & Co., Inc. Cyclic amine modulators of chemokine receptor activity
US7122207B2 (en) * 1998-05-22 2006-10-17 Bristol-Myers Squibb Company High drug load acid labile pharmaceutical composition
US6093743A (en) 1998-06-23 2000-07-25 Medinox Inc. Therapeutic methods employing disulfide derivatives of dithiocarbamates and compositions useful therefor
US6194391B1 (en) 1998-06-24 2001-02-27 Emory University 3′-azido-2′,3′-dideoxyuridine administration to treat HIV and related test protocol
CA2365495C (en) 1999-03-31 2007-01-02 The Procter & Gamble Company Viral treatment
US6136835A (en) 1999-05-17 2000-10-24 The Procter & Gamble Company Methods of treatment for viral infections

Also Published As

Publication number Publication date
PE20011179A1 (es) 2001-12-06
NZ522250A (en) 2004-09-24
CA2404687A1 (en) 2001-10-11
MXPA02009534A (es) 2003-05-14
PL366089A1 (en) 2005-01-24
LT2002099A (en) 2003-04-25
AU2001249591A1 (en) 2001-10-15
BR0109602A (pt) 2004-06-29
BG107157A (en) 2003-06-30
LT5045B (lt) 2003-08-25
CN1187052C (zh) 2005-02-02
ZA200207760B (en) 2004-01-30
SK12822002A3 (sk) 2003-02-04
RU2239435C2 (ru) 2004-11-10
WO2001074329A3 (en) 2002-05-10
RU2002126540A (ru) 2004-03-27
WO2001074329A2 (en) 2001-10-11
KR20030011805A (ko) 2003-02-11
CZ20023003A3 (cs) 2002-11-13
AR027748A1 (es) 2003-04-09
NO20024645L (no) 2002-09-27
US7135465B2 (en) 2006-11-14
IL151475A0 (en) 2003-04-10
JP2003528905A (ja) 2003-09-30
HUP0302631A2 (hu) 2003-11-28
CN1420774A (zh) 2003-05-28
LV12939B (en) 2003-04-20
GEP20043285B (en) 2004-07-26
NO20024645D0 (no) 2002-09-27
US20020002147A1 (en) 2002-01-03
EP1267879A2 (en) 2003-01-02

Similar Documents

Publication Publication Date Title
EE200200564A (et) Stavudiini sisaldavad toimeainet aeglustatult vabastavad graanulid
DE60125312D1 (de) Mikroarray
NO20026196L (no) Kinazolinditosylatsalt-forbindelser
NO20032585D0 (no) ABCA-1 forhöyende forbindelser
DK1619192T3 (da) Arylkondeserede azapolycykliske forbindelser
DE60125769D1 (de) Verbessertes elektroentionisierungssystem
AR028414A1 (es) Compuestos quimicos
DK1326832T3 (da) Kemiske forbindelser
DK1218009T3 (da) Quetiapingranulater
DE50108966D1 (de) Patrone
DE60110137D1 (de) Biochip
DE50109128D1 (de) Einlegesohle
ATE331046T1 (de) Magnesium enthaltendes entschwefelungsmittel
ID29697A (id) Tablet-tablet pengendali rayap
ATE372338T1 (de) Deshalogenverbindungen
NO20030303L (no) Kalsilytiske forbindelser
DE60132814D1 (de) Te
ATE283629T1 (de) Deltamethrinhaltiges, wasserdispergierbares granulat
NO20023508L (no) Kalsilyttiske forbindelser
NO20031837L (no) Kalsilytiske forbindelser
DE60120063D1 (de) Kassettenbehälter
DE50014876D1 (de) Achsmanschette
FI20002120A0 (fi) Sammutin
DE60120310D1 (de) Silberhalogenidemulsion
ATA8502000A (de) Einschraubventil