EE05319B1 - Akrloldistamtsiini derivaati sisaldav farmatseutiline kompositsioon, derivaadi kasutamine tuumorivastase ravimi valmistamiseks ning kombineeritud ravimpreparaat - Google Patents

Akrloldistamtsiini derivaati sisaldav farmatseutiline kompositsioon, derivaadi kasutamine tuumorivastase ravimi valmistamiseks ning kombineeritud ravimpreparaat

Info

Publication number
EE05319B1
EE05319B1 EEP200200681A EEP200200681A EE05319B1 EE 05319 B1 EE05319 B1 EE 05319B1 EE P200200681 A EEP200200681 A EE P200200681A EE P200200681 A EEP200200681 A EE P200200681A EE 05319 B1 EE05319 B1 EE 05319B1
Authority
EE
Estonia
Prior art keywords
derivative
acrylamine
preparation
tumor drug
pharmaceutical composition
Prior art date
Application number
EEP200200681A
Other languages
English (en)
Estonian (et)
Inventor
Cristina Rosa Geroni Maria
Cozzi Paolo
Beria Italo
Original Assignee
Pharmacia Italia S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Italia S.P.A. filed Critical Pharmacia Italia S.P.A.
Publication of EE200200681A publication Critical patent/EE200200681A/xx
Publication of EE05319B1 publication Critical patent/EE05319B1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
EEP200200681A 2000-06-23 2001-06-20 Akrloldistamtsiini derivaati sisaldav farmatseutiline kompositsioon, derivaadi kasutamine tuumorivastase ravimi valmistamiseks ning kombineeritud ravimpreparaat EE05319B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0015444.3A GB0015444D0 (en) 2000-06-23 2000-06-23 Combined therapy against tumors comprising substituted acryloyl distamycin derivatives and topoisomerase I and II inhibitors
PCT/EP2001/007059 WO2001097789A2 (en) 2000-06-23 2001-06-20 Pharmaceutical compositions comprising acryloyl distamycin derivatives and topoisomerase i and ii inhibitors

Publications (2)

Publication Number Publication Date
EE200200681A EE200200681A (et) 2004-06-15
EE05319B1 true EE05319B1 (et) 2010-08-16

Family

ID=9894285

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200200681A EE05319B1 (et) 2000-06-23 2001-06-20 Akrloldistamtsiini derivaati sisaldav farmatseutiline kompositsioon, derivaadi kasutamine tuumorivastase ravimi valmistamiseks ning kombineeritud ravimpreparaat

Country Status (27)

Country Link
US (1) US20030162722A1 (es)
EP (1) EP1292290B1 (es)
JP (1) JP2003535890A (es)
KR (1) KR100853955B1 (es)
CN (1) CN1241573C (es)
AT (1) ATE323483T1 (es)
AU (2) AU2001278463B2 (es)
BR (1) BR0111813A (es)
CA (1) CA2411172C (es)
CZ (1) CZ20024155A3 (es)
DE (1) DE60118914T2 (es)
DK (1) DK1292290T3 (es)
EA (1) EA006684B1 (es)
EE (1) EE05319B1 (es)
ES (1) ES2261448T3 (es)
GB (1) GB0015444D0 (es)
HK (1) HK1054334B (es)
HU (1) HUP0301257A2 (es)
IL (1) IL153177A0 (es)
MX (1) MXPA02012163A (es)
NO (1) NO329783B1 (es)
NZ (1) NZ523000A (es)
PL (1) PL200503B1 (es)
PT (1) PT1292290E (es)
SK (1) SK287549B6 (es)
WO (1) WO2001097789A2 (es)
ZA (1) ZA200209834B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0015447D0 (en) * 2000-06-23 2000-08-16 Pharmacia & Upjohn Spa Combined therapy against tumors comprising substituted acryloyl derivates and alkylating agents
GB0015444D0 (en) * 2000-06-23 2000-08-16 Pharmacia & Upjohn Spa Combined therapy against tumors comprising substituted acryloyl distamycin derivatives and topoisomerase I and II inhibitors
US20060084612A1 (en) * 2002-01-02 2006-04-20 Geroni Maria C Combined therapy against tumors comprising substituted acryloyl distamycin derivatives and protein kinase (serine/threonine kinase) inhibitors
CN100438913C (zh) * 2004-11-22 2008-12-03 山东蓝金生物工程有限公司 一种抗癌药物组合物
MD35Z (ro) * 2008-12-02 2010-01-31 Василе ЖОВМИР Metodă de apreciere a riscului dezvoltării carcinomului neinvaziv in situ al glandei mamare
MD24Z (ro) * 2008-12-02 2010-01-31 Василе ЖОВМИР Metodă de tratament diferenţiat al carcinomului neinvaziv al glandei mamare
MD23Z (ro) * 2008-12-02 2010-01-31 Василе ЖОВМИР Metodă de tratament diferenţiat al carcinomului lobular in situ neinvaziv al glandei mamare
MD36Z (ro) * 2008-12-02 2010-01-31 Василе ЖОВМИР Metodă de tratament diferenţiat al carcinomului ductal in situ neinvaziv al glandei mamare
AU2011274229A1 (en) 2010-07-02 2013-01-10 Angiochem Inc. Short and D-amino acid-containing polypeptides for therapeutic conjugates and uses thereof
CN109718228A (zh) * 2017-10-30 2019-05-07 沈阳药科大学 米托蒽醌的抗肿瘤淋巴转移作用及其药物制剂

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9615692D0 (en) * 1996-07-25 1996-09-04 Pharmacia Spa Acryloyl substituted distamycin derivatives, process for preparing them, and their use as antitumor and antiviral agents
GB9623522D0 (en) 1996-11-11 1997-01-08 Pharmacia & Upjohn Spa Benzoheterocycle distamycin derivatives process for preparing them and their use as antitumour and antiviral agents
GB9727524D0 (en) * 1997-12-31 1998-02-25 Pharmacia & Upjohn Spa Synergistic antitumor composition containing a biologically active ureido compound
GB9806692D0 (en) * 1998-03-27 1998-05-27 Pharmacia & Upjohn Spa Benzoheterocyclic distamycin derivatives, process for preparing them and their use as antitumour agents
GB0015444D0 (en) * 2000-06-23 2000-08-16 Pharmacia & Upjohn Spa Combined therapy against tumors comprising substituted acryloyl distamycin derivatives and topoisomerase I and II inhibitors

Also Published As

Publication number Publication date
DE60118914T2 (de) 2006-12-21
EA200300060A1 (ru) 2003-04-24
HK1054334A1 (en) 2003-11-28
EE200200681A (et) 2004-06-15
WO2001097789A3 (en) 2002-05-16
AU7846301A (en) 2002-01-02
DK1292290T3 (da) 2006-07-10
KR20030019448A (ko) 2003-03-06
US20030162722A1 (en) 2003-08-28
KR100853955B1 (ko) 2008-08-25
SK18332002A3 (sk) 2003-07-01
ZA200209834B (en) 2003-12-04
CZ20024155A3 (cs) 2003-04-16
CA2411172C (en) 2009-11-17
NO20026078D0 (no) 2002-12-18
EP1292290A2 (en) 2003-03-19
PL360297A1 (en) 2004-09-06
ES2261448T3 (es) 2006-11-16
BR0111813A (pt) 2003-05-20
NO20026078L (no) 2002-12-18
WO2001097789A2 (en) 2001-12-27
NO329783B1 (no) 2010-12-13
NZ523000A (en) 2005-12-23
CA2411172A1 (en) 2001-12-27
HUP0301257A2 (hu) 2003-08-28
SK287549B6 (sk) 2011-01-04
JP2003535890A (ja) 2003-12-02
PT1292290E (pt) 2006-08-31
DE60118914D1 (de) 2006-05-24
CN1437474A (zh) 2003-08-20
MXPA02012163A (es) 2003-04-25
EP1292290B1 (en) 2006-04-19
ATE323483T1 (de) 2006-05-15
HK1054334B (zh) 2006-09-22
AU2001278463B2 (en) 2006-02-23
EA006684B1 (ru) 2006-02-24
GB0015444D0 (en) 2000-08-16
CN1241573C (zh) 2006-02-15
IL153177A0 (en) 2003-06-24
PL200503B1 (pl) 2009-01-30

Similar Documents

Publication Publication Date Title
ATE261974T1 (de) Hoch-lipophile campothecin-derivate
WO2002057261A3 (en) Diaminothiazoles and their use as inhibitors of cyclin-dependent kinase
WO2003053368A3 (en) Chalcone derivatives and their use to treat diseases
ATE309786T1 (de) Liposomale antineoplastische arzneimittel und deren verwendungen
HUP0303271A2 (hu) Rapamycin felhasználása rák kezelésére alkalmas gyógyszerkészítmény elõállítására
CY1111693T1 (el) Αντιιικοι παραγοντες
WO2006011050A3 (en) Pyridine derivatives
MY141739A (en) Substituted quinazoline derivatives as inhibitors of aurora kinases
NO20072258L (no) Farmasøytiske sammensetninger omfattende et camptothecinderivat
YU87202A (sh) Derivati arilmetilamina koji se koriste kao inhibitori triptaze
EE05319B1 (et) Akrloldistamtsiini derivaati sisaldav farmatseutiline kompositsioon, derivaadi kasutamine tuumorivastase ravimi valmistamiseks ning kombineeritud ravimpreparaat
IL151198A0 (en) Tricyclic imidazopyridine derivatives and pharmaceutical compositions containing the same
TR200402070T4 (tr) Siklobüten-dion türevleri ve bunların damar sertliği tedavisinde kullanımı
MXPA02004441A (es) Derivados de isoxazol como inhibidores de la fosfodiesterasa.
AU2001296699A1 (en) Condensed pyrazindione derivatives as pde inhibitors
TR200302134T4 (tr) 2-metil-tiazolidin-2,4-dikarboksilik asit ve/veya bunun fizyolojik olarak uygun tuzlarının anti-kanser ajanları olarak kullanımı.
HUP0302629A2 (hu) Camptotechin és sztilbénszármazékok kombinációját tartalmazó gyógyszerkészítmények rák kezelésére
EE200200688A (et) Akrüloüüldistamütsiini derivaati, mikrotuubulivastast toimeainet ja/või antimetaboliiti sisaldav farmatseutiline kompositsioon, derivaadi kasutamine tuumorivastase ravimi valmistamiseks ning kombineeritud ravimpreparaat
MXPA02012209A (es) Terapia combinada contra tumores que comprende derivados de bistamicina acriloilo substituida y agentes de alquilacion.
IL150979A0 (en) 9-alkylamino-1-nitroacridine derivatives
UA81617C2 (en) Chalcone derivatives and their use
MY128457A (en) 2-aminocarbonyl-9h-purine derivatives

Legal Events

Date Code Title Description
GB1A Change in the ownership or in the address of the owner
KB4A Valid patent at the end of a year

Effective date: 20101231

MM4A Lapsed by not paying the annual fees

Effective date: 20110620