EE05249B1 - (E)-5-(2-bromovinl)-2'-desoksuridiini valmistamise meetod - Google Patents
(E)-5-(2-bromovinl)-2'-desoksuridiini valmistamise meetodInfo
- Publication number
- EE05249B1 EE05249B1 EEP200300402A EEP200300402A EE05249B1 EE 05249 B1 EE05249 B1 EE 05249B1 EE P200300402 A EEP200300402 A EE P200300402A EE P200300402 A EEP200300402 A EE P200300402A EE 05249 B1 EE05249 B1 EE 05249B1
- Authority
- EE
- Estonia
- Prior art keywords
- deoxidine
- bromovin
- uridine
- preparation
- deoxidine uridine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10109657A DE10109657A1 (de) | 2001-02-28 | 2001-02-28 | Verfahren zur Herstellung von (E)-5-(2-Bromvinyl)-2`-desoxyuridin |
| PCT/EP2002/001833 WO2002068443A1 (en) | 2001-02-28 | 2002-02-21 | Process for the preparation of (e)-5-(2-bromovinyl)-2'-deoxyuridine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EE200300402A EE200300402A (et) | 2003-12-15 |
| EE05249B1 true EE05249B1 (et) | 2009-12-15 |
Family
ID=7675814
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EEP200300402A EE05249B1 (et) | 2001-02-28 | 2002-02-21 | (E)-5-(2-bromovinl)-2'-desoksuridiini valmistamise meetod |
Country Status (32)
| Country | Link |
|---|---|
| US (1) | US6864366B2 (ko) |
| EP (1) | EP1363928B1 (ko) |
| JP (1) | JP2004521132A (ko) |
| KR (1) | KR100853280B1 (ko) |
| CN (1) | CN1219789C (ko) |
| AR (1) | AR032908A1 (ko) |
| AT (1) | ATE294810T1 (ko) |
| BG (1) | BG66333B1 (ko) |
| BR (1) | BRPI0207566B8 (ko) |
| CA (1) | CA2439319C (ko) |
| CZ (1) | CZ299318B6 (ko) |
| DE (2) | DE10109657A1 (ko) |
| DK (1) | DK1363928T3 (ko) |
| EA (1) | EA006156B1 (ko) |
| EE (1) | EE05249B1 (ko) |
| ES (1) | ES2239713T3 (ko) |
| HK (1) | HK1060134A1 (ko) |
| HR (1) | HRP20030671B1 (ko) |
| HU (1) | HU229136B1 (ko) |
| IL (2) | IL157573A0 (ko) |
| MA (1) | MA26267A1 (ko) |
| MX (1) | MXPA03007624A (ko) |
| MY (1) | MY133371A (ko) |
| PE (1) | PE20020892A1 (ko) |
| PL (1) | PL210150B1 (ko) |
| PT (1) | PT1363928E (ko) |
| RS (1) | RS50761B (ko) |
| SK (1) | SK287283B6 (ko) |
| TN (1) | TNSN03049A1 (ko) |
| UA (1) | UA75110C2 (ko) |
| WO (1) | WO2002068443A1 (ko) |
| ZA (1) | ZA200306639B (ko) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101066987B (zh) * | 2007-06-14 | 2010-05-19 | 上海交通大学 | 溴呋啶的制备方法 |
| RS62721B1 (sr) | 2011-03-01 | 2022-01-31 | NuCana plc | Farmaceutska formulacija koja sadrži fosforamidatni derivat 5-fluoro-2’-deoksiuridina za upotrebu u lečenju kancera |
| GB201715011D0 (en) | 2017-09-18 | 2017-11-01 | Nucana Biomed Ltd | Floxuridine synthesis |
| CN115043894A (zh) * | 2022-06-22 | 2022-09-13 | 华润双鹤药业股份有限公司 | 一种溴夫定起始物料异构体单晶及其制备方法和应用 |
| KR20240086637A (ko) | 2022-12-10 | 2024-06-18 | (주)일승 | Ptc 히터 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB215399A (en) | 1922-11-07 | 1924-05-07 | Frederic Valerius Hetzel | Improvements in sprocket-wheels |
| GB1601020A (en) * | 1978-04-24 | 1981-10-21 | Stichting Grega Vzw | 2'-deoxy-5 (2-halogenovinyl)-uridines |
| HU187736B (en) * | 1982-08-04 | 1986-02-28 | Mta Koezponti Kemiai Kutato Intezet,Hu | Process for producing /e/ -5-/2-bromovinyl/-2-comma above-deoxyuridine and o-acyl derivatives |
| DE59202433D1 (de) * | 1991-05-06 | 1995-07-13 | Ciba Geigy Ag | Verfahren zur Herstellung von Benzolsulfonamiden. |
-
2001
- 2001-02-28 DE DE10109657A patent/DE10109657A1/de not_active Withdrawn
-
2002
- 2002-02-21 KR KR1020037011176A patent/KR100853280B1/ko active IP Right Grant
- 2002-02-21 BR BR0207566-0 patent/BRPI0207566B8/pt not_active IP Right Cessation
- 2002-02-21 JP JP2002567953A patent/JP2004521132A/ja active Pending
- 2002-02-21 ES ES02722111T patent/ES2239713T3/es not_active Expired - Lifetime
- 2002-02-21 DK DK02722111T patent/DK1363928T3/da active
- 2002-02-21 US US10/468,901 patent/US6864366B2/en not_active Expired - Lifetime
- 2002-02-21 UA UA2003076955A patent/UA75110C2/uk unknown
- 2002-02-21 WO PCT/EP2002/001833 patent/WO2002068443A1/en active IP Right Grant
- 2002-02-21 MX MXPA03007624A patent/MXPA03007624A/es active IP Right Grant
- 2002-02-21 CN CNB028055764A patent/CN1219789C/zh not_active Expired - Lifetime
- 2002-02-21 CZ CZ20032295A patent/CZ299318B6/cs not_active IP Right Cessation
- 2002-02-21 PT PT02722111T patent/PT1363928E/pt unknown
- 2002-02-21 CA CA2439319A patent/CA2439319C/en not_active Expired - Lifetime
- 2002-02-21 AT AT02722111T patent/ATE294810T1/de active
- 2002-02-21 SK SK1064-2003A patent/SK287283B6/sk not_active IP Right Cessation
- 2002-02-21 PL PL363611A patent/PL210150B1/pl unknown
- 2002-02-21 DE DE60203998T patent/DE60203998T2/de not_active Expired - Lifetime
- 2002-02-21 IL IL15757302A patent/IL157573A0/xx unknown
- 2002-02-21 EE EEP200300402A patent/EE05249B1/xx unknown
- 2002-02-21 EP EP02722111A patent/EP1363928B1/en not_active Expired - Lifetime
- 2002-02-21 EA EA200300761A patent/EA006156B1/ru not_active IP Right Cessation
- 2002-02-21 HU HU0303323A patent/HU229136B1/hu unknown
- 2002-02-21 RS YUP-671/03A patent/RS50761B/sr unknown
- 2002-02-27 MY MYPI20020674A patent/MY133371A/en unknown
- 2002-02-27 PE PE2002000166A patent/PE20020892A1/es active IP Right Grant
- 2002-02-27 AR ARP020100708A patent/AR032908A1/es active IP Right Grant
-
2003
- 2003-07-08 TN TNPCT/EP2002/001833A patent/TNSN03049A1/en unknown
- 2003-07-22 MA MA27247A patent/MA26267A1/fr unknown
- 2003-08-25 BG BG108129A patent/BG66333B1/bg unknown
- 2003-08-25 HR HR20030671A patent/HRP20030671B1/xx not_active IP Right Cessation
- 2003-08-26 ZA ZA200306639A patent/ZA200306639B/en unknown
- 2003-08-26 IL IL157573A patent/IL157573A/en active IP Right Grant
-
2004
- 2004-05-05 HK HK04103150A patent/HK1060134A1/xx not_active IP Right Cessation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| KB4A | Valid patent at the end of a year |
Effective date: 20101231 |